fluorouracil and 10-hydroxycamptothecin

fluorouracil has been researched along with 10-hydroxycamptothecin in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's1 (7.14)18.2507
2000's10 (71.43)29.6817
2010's1 (7.14)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Chen, Y; Ding, J; Gao, H; Huang, M; Li, C; Lu, W; Shen, H; Sun, J; Zhang, X1
Tang, HF; Yi, YH; Zhang, SY1
Shen, ZM; Wang, XW; Xu, B; Yang, JL; Yu, WJ1
Li, N; Ou, Q; Shen, B; Wang, H; Yu, B; Zhang, H; Zheng, M1
Agrawal, S; Nan, L; Wang, H; Yu, D; Zhang, R1
Agrawal, S; Lindsey, JR; Nan, L; Wang, H; Yu, D; Zhang, R1
Chen, ZH; Feng, B1
Ji, J; Ji, YB; Lin, YZ; Liu, BY; Yuan, F; Zhang, J; Zhu, ZG1
Cai, W; Chen, JP; Li, XY; Wu, XY; Yao, DF; Yu, JW; Yu, ZJ; Yuan, HX; Yuan, Y1
Feng, LF; Lei, XY; Liao, DF; Tang, SS; Zhong, M; Zhu, BY1
Cai, X; Guo, YW; Lin, F; Sun, YJ; Tang, LN; Tang, XC; Yao, Y; Zhang, W; Zhao, H1
Chen, P; Lin, F; Sun, Y; Tang, L; Yao, Y; Zhao, H1
Chen, SZ; Shang, BY; Shang, Y; Zhen, YS1
Ding, D; Gao, F; Han, D; Jin, C; Li, J; Li, Y; Lv, C; Sun, Y; Tan, W; Wang, R; Xie, S; Yang, C1

Trials

1 trial(s) available for fluorouracil and 10-hydroxycamptothecin

ArticleYear
Evaluation of HCPTd1,d14-double passaged intervening chemotherapy protocol for hepatocellular carcinoma.
    World journal of gastroenterology, 2005, Sep-07, Volume: 11, Issue:33

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Hepatic Artery; Humans; Liver Neoplasms; Male; Middle Aged; Portal Vein; Treatment Outcome

2005

Other Studies

13 other study(ies) available for fluorouracil and 10-hydroxycamptothecin

ArticleYear
Synthesis and antitumor activity of 7-ethyl-9-alkyl derivatives of camptothecin.
    Bioorganic & medicinal chemistry letters, 2005, Apr-15, Volume: 15, Issue:8

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Humans

2005
Bioactive triterpene glycosides from the sea cucumber Holothuria fuscocinerea.
    Journal of natural products, 2006, Volume: 69, Issue:10

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Glycosides; Humans; Molecular Structure; Sea Cucumbers; Triterpenes

2006
[Cytotoxicity of hydroxycamptothecin and four other antineoplastic agents on KB cells].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1987, Volume: 8, Issue:1

    Topics: Alkaloids; Amaryllidaceae Alkaloids; Antineoplastic Agents, Phytogenic; Camptothecin; Colony-Forming Units Assay; Fluorouracil; Harringtonines; Homoharringtonine; Humans; Indolizines; KB Cells; Vincristine

1987
The influence of the p53 gene on the in vitro chemosensitivity of colorectal cancer cells.
    Journal of cancer research and clinical oncology, 1999, Volume: 125, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Apoptosis; Camptothecin; Colorectal Neoplasms; Drug Resistance, Neoplasm; Female; Fluorouracil; Genes, p53; Humans; Male; Middle Aged; Mutation; Retrospective Studies

1999
Antisense anti-MDM2 oligonucleotides as a novel therapeutic approach to human breast cancer: in vitro and in vivo activities and mechanisms.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:11

    Topics: Animals; Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Camptothecin; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA, Antisense; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Humans; Mice; Mice, Nude; Mutation; Neoplasm Transplantation; Nuclear Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2001
Anti-tumor efficacy of a novel antisense anti-MDM2 mixed-backbone oligonucleotide in human colon cancer models: p53-dependent and p53-independent mechanisms.
    Molecular medicine (Cambridge, Mass.), 2002, Volume: 8, Issue:4

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Camptothecin; Colorectal Neoplasms; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Mice; Mice, Nude; Neoplasm Proteins; Neoplasm Transplantation; Nuclear Proteins; Oligonucleotides, Antisense; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Survival Rate; Treatment Outcome; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2002
[Effect of the change of caspase-3 activity on the neoadjuvant chemotherapy-induced apoptosis of large-intestinal carcinoma cells].
    Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University, 2003, Volume: 28, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Caspase 3; Caspases; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged

2003
[Antitumor effects of chemotherapeutic drugs on fresh human gastric cancer cells and their relationships to expressions of P-glycoprotein and glutathione S transferase-pi].
    Ai zheng = Aizheng = Chinese journal of cancer, 2005, Volume: 24, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Camptothecin; Cell Nucleus; Cisplatin; Cytoplasm; Doxorubicin; Drug Resistance, Neoplasm; Female; Fluorouracil; Glutathione S-Transferase pi; Humans; Male; Middle Aged; Mitomycin; Stomach Neoplasms; Tumor Cells, Cultured

2005
Bcl-2 siRNA induced apoptosis and increased sensitivity to 5-fluorouracil and HCPT in HepG2 cells.
    Journal of drug targeting, 2006, Volume: 14, Issue:1

    Topics: Antimetabolites, Antineoplastic; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Camptothecin; Caspase 3; Caspases; Cell Line, Tumor; Drug Delivery Systems; Drug Synergism; Flow Cytometry; Fluorouracil; Genes, bcl-2; Humans; Liver Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Tetrazolium Salts; Thiazoles

2006
Oxaliplatin plus hydroxycamptothecine versus oxaliplatin plus 5-fluorouracil and leucovorin in treatment of advanced colorectal cancer.
    Chinese medical journal, 2006, Nov-05, Volume: 119, Issue:21

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Survival Rate; Treatment Outcome

2006
Combined chemotherapy of hydroxycampothecin with oxaliplatin as an adjuvant treatment for human colorectal cancer.
    The Tohoku journal of experimental medicine, 2008, Volume: 215, Issue:3

    Topics: Adjuvants, Pharmaceutic; Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Cell Line, Tumor; Colorectal Neoplasms; Female; Fluorouracil; Humans; Leucovorin; Male; Mice; Middle Aged; Neoplasm Transplantation; Organoplatinum Compounds; Oxaliplatin

2008
[Lidamycin inhibits the proliferation of HERG K+ channel highly expressing cancer cells and shows synergy with anticancer drugs].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2011, Volume: 46, Issue:11

    Topics: Aminoglycosides; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Drug Synergism; Enediynes; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluorouracil; HT29 Cells; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Xenograft Model Antitumor Assays

2011
Construction of Bispecific Aptamer-Drug Conjugate by a Hybrid Chemical and Biological Approach.
    Bioconjugate chemistry, 2020, 05-20, Volume: 31, Issue:5

    Topics: Aminobenzoates; Aptamers, Nucleotide; Camptothecin; Cell Line, Tumor; Fluorouracil; Humans; Oligopeptides; Pharmaceutical Preparations

2020