fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether has been researched along with acetylcysteine in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anders, MW; Baggs, RB; Iyer, RA; Uttamsingh, V | 1 |
| Hoffman, GM; Jubert, C; Kharasch, ED; Spracklin, DK | 1 |
| Jubert, C; Kharasch, ED | 1 |
| Gul Altuntas, T; Kharasch, ED | 1 |
| Altuntas, TG; Kharasch, ED; Park, SB | 1 |
1 trial(s) available for fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether and acetylcysteine
| Article | Year |
|---|---|
Compound A uptake and metabolism to mercapturic acids and 3,3,3-trifluoro-2-fluoromethoxypropanoic acid during low-flow sevoflurane anesthesia: biomarkers for exposure, risk assessment, and interspecies comparison.
Topics: Acetylation; Acetylcysteine; Adult; Aged; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Cysteine; Elective Surgical Procedures; Ethers; Female; Gas Chromatography-Mass Spectrometry; Glutathione; Humans; Hydrocarbons, Fluorinated; Inactivation, Metabolic; Male; Methyl Ethers; Middle Aged; Propionates; Rats; Sevoflurane | 1999 |
4 other study(ies) available for fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether and acetylcysteine
| Article | Year |
|---|---|
Fate and toxicity of 2-(fluoromethoxy)-1,1,3,3,3-pentafluoro-1-propene (compound A)-derived mercapturates in male, Fischer 344 rats.
Topics: Acetylcysteine; Acyltransferases; Anesthetics, Inhalation; Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Cytosol; Dealkylation; Drug Contamination; Ethers; Hydrocarbons, Fluorinated; Kidney Diseases; Magnetic Resonance Spectroscopy; Male; Methyl Ethers; Rats; Rats, Inbred F344; Sevoflurane | 1998 |
Dose-dependent metabolism of fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (compound A), an anesthetic degradation product, to mercapturic acids and 3,3,3-trifluoro-2-(fluoromethoxy)propanoic acid in rats.
Topics: Acetylcysteine; Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Ethers; Hydrocarbons, Fluorinated; Male; Propionates; Rats; Rats, Inbred F344 | 1999 |
Biotransformation of L-cysteine S-conjugates and N-acetyl-L-cysteine S-conjugates of the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (compound A) in human kidney in vitro: interindividual variability in N-acety
Topics: Acetylation; Acetylcysteine; Anesthetics, Inhalation; Biotransformation; Cysteine; Ethers; Free Radical Scavengers; Humans; Hydrocarbons, Fluorinated; Kidney; Lyases; Methyl Ethers; Sevoflurane | 2002 |
Sulfoxidation of cysteine and mercapturic acid conjugates of the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (compound A).
Topics: Acetylcysteine; Anesthetics, Inhalation; Animals; Cysteine; Cytochrome P-450 Enzyme System; Ethers; Humans; Hydrocarbons, Fluorinated; Kidney; Methyl Ethers; Microsomes, Liver; Oxidation-Reduction; Rats; Sevoflurane; Sulfoxides | 2004 |