Page last updated: 2024-08-18

fluorodeoxyuridylate and uracil

fluorodeoxyuridylate has been researched along with uracil in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's6 (66.67)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fujimaki, M; Kurokawa, M; Kuroki, Y; Ochiai, H; Okamoto, M; Tazawa, K; Yamashita, I1
Goulian, M; Ingraham, HA; Tseng, BY1
Santi, DV1
Hirano, K; Kanehira, E; Kawakami, K; Kawashima, S; Nagasato, A; Omura, K; Shirasaka, T; Tawaraya, K; Watanabe, S; Watanabe, Y1
Adachi, I; Hashimoto, T; Ishida, F; Kawakami, K; Matsu, T; Omura, K; Watanabe, Y1
Fujimaki, M; Katuyama, S; Kuroki, Y; Okamoto, M; Sakamoto, T; Tazawa, K; Yamashita, I1
Adamowicz, L; Leś, A; Rode, W1
Erdélyi-Tóth, V; Jeney, A; Katona, C; Kovács, P; Kralovánszky, J; Noordhuis, P; Otvös, L; Pandi, E; Peters, GJ; Van der Wilt, CL1
de Carvalho, AI; Gomes, J; Günther Sillero, MA; Martins, S; Pérez-Zúñiga, F; Sillero, A; Silles, E1

Reviews

1 review(s) available for fluorodeoxyuridylate and uracil

ArticleYear
Perspective on the design and biochemical pharmacology of inhibitors of thymidylate synthetase.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:2

    Topics: Antineoplastic Agents; Deoxyuracil Nucleotides; Deoxyuridine; Fluorodeoxyuridylate; Fluorouracil; Methotrexate; Methyltransferases; Protein Binding; Structure-Activity Relationship; Thymidylate Synthase; Uracil

1980

Other Studies

8 other study(ies) available for fluorodeoxyuridylate and uracil

ArticleYear
[Antitumor activity of T-506, a novel synthetic FUDR derivative, on murine colon cancer and its hepatic metastasis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:8

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Floxuridine; Fluorodeoxyuridylate; Liver Neoplasms; Mice; Mice, Inbred BALB C; Tegafur; Uracil

1991
Mechanism for exclusion of 5-fluorouracil from DNA.
    Cancer research, 1980, Volume: 40, Issue:4

    Topics: Deoxyuracil Nucleotides; DNA; Fluorodeoxyuridylate; Fluorouracil; In Vitro Techniques; N-Glycosyl Hydrolases; Pyrophosphatases; Uracil

1980
The number of 5-fluoro-2'-deoxyuridine-5'-monophosphate binding sites and reduced folate pool in human colorectal carcinoma tissues: changes after tegafur and uracil treatment.
    Cancer research, 1995, Sep-01, Volume: 55, Issue:17

    Topics: Base Sequence; Binding Sites; Colorectal Neoplasms; Fluorodeoxyuridylate; Humans; Molecular Sequence Data; RNA, Messenger; Tegafur; Tetrahydrofolates; Thymidylate Synthase; Uracil

1995
[Changes of the number of FdUMP binding sites of thymidylate synthase and folate pools in human colorectal carcinomas following the administration of tegafur and uracil: preliminary report].
    Nihon Geka Gakkai zasshi, 1993, Volume: 94, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Binding Sites; Colorectal Neoplasms; Fluorodeoxyuridylate; Folic Acid; Humans; Tegafur; Thymidylate Synthase; Uracil

1993
Inhibitory effects of fluorinated pyrimidines, 5'-DFUR, UFT and T-506, in a model of hepatic metastasis of mouse colon 26 adenocarcinoma-assessment of inhibitory activity and adverse reactions at the maximum tolerated dose.
    Clinical & experimental metastasis, 1997, Volume: 15, Issue:3

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Body Weight; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Combinations; Female; Floxuridine; Fluorodeoxyuridylate; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Tegafur; Uracil

1997
Modeling of reaction steps relevant to deoxyuridylate (dUMP) enzymatic methylation and thymidylate synthase mechanism-based inhibition.
    Journal of biomolecular structure & dynamics, 1998, Volume: 15, Issue:4

    Topics: Algorithms; Cysteine; Deoxycytidine Monophosphate; Deoxyuracil Nucleotides; Fluorodeoxyuridylate; Methylation; Models, Chemical; Quantum Theory; Sulfhydryl Compounds; Tetrahydrofolates; Thymidylate Synthase; Uracil; Water

1998
5-ethyl-2'-deoxyuridine, a modulator of both antitumour action and pharmacokinetics of 5-fluorouracil.
    Journal of cancer research and clinical oncology, 1999, Volume: 125, Issue:12

    Topics: Animals; Antimetabolites, Antineoplastic; Area Under Curve; Colonic Neoplasms; Deoxyuridine; Dose-Response Relationship, Drug; Drug Synergism; Fluorodeoxyuridylate; Fluorouracil; Male; Metabolic Clearance Rate; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Time Factors; Treatment Outcome; Uracil; Uridine

1999
Synthesis of FUDP-N-acetylglucosamine and FUDP-glucose in Saccharomyces cerevisiae cells treated with 5-fluorouracil.
    FEMS yeast research, 2008, Volume: 8, Issue:2

    Topics: Aerobiosis; Alkaline Phosphatase; Antimetabolites; Chromatography, Liquid; Culture Media; Fermentation; Fluorodeoxyuridylate; Fluorouracil; Magnetic Resonance Spectroscopy; Microbial Viability; Phosphodiesterase I; Saccharomyces cerevisiae; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrum Analysis; Uracil; Uridine Diphosphate Glucose; Uridine Diphosphate Glucose Dehydrogenase; Uridine Diphosphate N-Acetylglucosamine

2008