Page last updated: 2024-08-18

fluorodeoxyuridylate and raltitrexed

fluorodeoxyuridylate has been researched along with raltitrexed in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (66.67)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Peters, GJ; Pinedo, HM; Telleman, F; van der Wilt, CL; van Triest, B1
Hekmat-Nejad, M; Rathod, PK1
Dabrowska, M; Michalski, R; Pawelczak, K; Rode, W; Wranicz, M; ZieliƱski, Z1
Jansen, G; Peters, GJ; Pinedo, HM; Telleman, F; van der Wilt, CL; van Triest, B1
Antony, S; Gmeiner, WH; Kohlhagen, G; Liao, ZY; Pommier, Y; Sordet, O; Zhang, HL1
Bijnsdorp, IV; Comijn, EM; Gmeiner, WH; Padron, JM; Peters, GJ1

Other Studies

6 other study(ies) available for fluorodeoxyuridylate and raltitrexed

ArticleYear
Cross-resistance to thymidylate synthase inhibitors in P-glycoprotein and non-P-glycoprotein cell lines.
    Advances in experimental medicine and biology, 1994, Volume: 370

    Topics: Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Squamous Cell; Cell Cycle; Cell Line; Clone Cells; Doxorubicin; Drug Resistance, Multiple; Fluorodeoxyuridylate; Fluorouracil; Humans; Lung Neoplasms; Quinazolines; Thiophenes; Thymidylate Synthase; Tumor Cells, Cultured

1994
Kinetics of Plasmodium falciparum thymidylate synthase: interactions with high-affinity metabolites of 5-fluoroorotate and D1694.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:7

    Topics: Animals; Antimalarials; Enzyme Inhibitors; Fluorodeoxyuridylate; Kinetics; Orotic Acid; Plasmodium falciparum; Quinazolines; Thiophenes; Thymidylate Synthase

1996
Trichinella spiralis thymidylate synthase: developmental pattern, isolation, molecular properties, and inhibition by substrate and cofactor analogues.
    Biochemical and biophysical research communications, 1996, Nov-12, Volume: 228, Issue:2

    Topics: Animals; Chromatography, Affinity; Enzyme Inhibitors; Fluorodeoxyuridylate; Folic Acid; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Humans; Kinetics; Larva; Liver; Liver Regeneration; Muscles; Quinazolines; Rats; Structure-Activity Relationship; Thiophenes; Thymidylate Synthase; Trichinella spiralis

1996
Cross-resistance to antifolates in multidrug resistant cell lines with P-glycoprotein or multidrug resistance protein expression.
    Biochemical pharmacology, 1997, Jun-15, Volume: 53, Issue:12

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Division; Drug Resistance, Multiple; Fluorodeoxyuridylate; Fluorouracil; Folic Acid Antagonists; Gene Expression Regulation; Humans; Indoles; Isoindoles; Methotrexate; Peptide Synthases; Polymerase Chain Reaction; Quinazolines; RNA, Messenger; Thiophenes; Thymidylate Synthase; Tumor Cells, Cultured

1997
A novel polypyrimidine antitumor agent FdUMP[10] induces thymineless death with topoisomerase I-DNA complexes.
    Cancer research, 2005, Jun-01, Volume: 65, Issue:11

    Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Death; DNA Damage; DNA Topoisomerases, Type I; DNA, Neoplasm; DNA, Single-Stranded; Drug Screening Assays, Antitumor; Fluorodeoxyuridylate; Fluorouracil; Leukemia P388; Mice; Quinazolines; Thiophenes; Thymidine; Thymidylate Synthase; Topoisomerase I Inhibitors

2005
Mechanisms of action of FdUMP[10]: metabolite activation and thymidylate synthase inhibition.
    Oncology reports, 2007, Volume: 18, Issue:1

    Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Fluorodeoxyuridylate; Fluorouracil; Folic Acid Antagonists; Glutamates; Guanine; Mammary Neoplasms, Experimental; Mice; Molecular Structure; Pemetrexed; Quinazolines; Thiophenes; Thymidylate Synthase; Tumor Cells, Cultured

2007