fluorodeoxyuridylate has been researched along with methotrexate in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (82.35) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gaumont, Y; Hsiao, MC; Kalman, TI; Kisliuk, RL; Nair, IG; Nair, MG; Nanavati, NT | 1 |
| Chabner, BA; Donehower, RC; Myers, CE | 1 |
| Haurani, FI | 1 |
| Kisliuk, RL; Sharma, RK; Verma, SP; Wallach, DF | 1 |
| Harrap, KR; Jackson, RC | 1 |
| Briand, C; Gilli, R; Lopez, C; Sari, JC | 1 |
| Dunlap, RB; Zapf, JW | 1 |
| Almersjö, O; Berne, MH; Frösing, R; Gustavsson, BG; Spears, PC | 1 |
| Bertino, JR; Fernandes, DJ; Moroson, BA | 1 |
| Kimura, K; Tanaka, M; Yoshida, S | 1 |
| Bailey, BD; Bowen, D; Guernsey, LA | 1 |
| Bruice, TW; Garrett, C; Santi, DV; Wataya, Y | 1 |
| Dunlap, RB; Ellis, PD; Lewis, CA | 1 |
| Bertino, JR; Fernandes, DJ; Mini, E | 1 |
| Santi, DV | 1 |
| Braakhuis, BJ; De Jong, M; Peters, GJ; Pinedo, HM; Smid, K; Van der Wilt, CL | 1 |
| Jansen, G; Peters, GJ; Pinedo, HM; Telleman, F; van der Wilt, CL; van Triest, B | 1 |
1 review(s) available for fluorodeoxyuridylate and methotrexate
| Article | Year |
|---|---|
Perspective on the design and biochemical pharmacology of inhibitors of thymidylate synthetase.
Topics: Antineoplastic Agents; Deoxyuracil Nucleotides; Deoxyuridine; Fluorodeoxyuridylate; Fluorouracil; Methotrexate; Methyltransferases; Protein Binding; Structure-Activity Relationship; Thymidylate Synthase; Uracil | 1980 |
16 other study(ies) available for fluorodeoxyuridylate and methotrexate
| Article | Year |
|---|---|
Folate analogues. 26. Syntheses and antifolate activity of 10-substituted derivatives of 5,8-dideazafolic acid and of the poly-gamma-glutamyl metabolites of N10-propargyl-5,8-dideazafolic acid (PDDF).
Topics: Animals; Chemical Phenomena; Chemistry; Folic Acid; Folic Acid Antagonists; Lacticaseibacillus casei; Leukemia L1210; Quinazolines; Streptococcus; Structure-Activity Relationship; Thymidylate Synthase | 1986 |
New developments on the mechanisms of action of antineoplastic drugs.
Topics: Antineoplastic Agents; Bleomycin; Doxorubicin; Drug Interactions; Drug Synergism; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Humans; Methotrexate | 1979 |
Inhibition of thymidylate synthetase of the human lymphocytes.
Topics: Deoxyuracil Nucleotides; Fluorodeoxyuridylate; Humans; Kinetics; Leucovorin; Lymphocytes; Methotrexate; Methyltransferases; Thymidylate Synthase | 1979 |
Study of thymidylate synthetase-function by laser Raman spectroscopy.
Topics: Binding Sites; Drug Resistance, Microbial; Fluorodeoxyuridylate; Lacticaseibacillus casei; Lasers; Methotrexate; Methyltransferases; Protein Binding; Protein Conformation; Scattering, Radiation; Spectrophotometry, Infrared; Spectrum Analysis; Tetrahydrofolates; Thymidylate Synthase | 1975 |
Enzyme kinetics and combination chemotherapy: an appraisal of current concepts.
Topics: Antimetabolites; Cell Line; Cell-Free System; Cells, Cultured; Drug Therapy, Combination; Enzyme Inhibitors; Enzymes; Fluorodeoxyuridylate; Fluorouracil; Folic Acid Antagonists; Kinetics; Macromolecular Substances; Methotrexate; Models, Biological | 1975 |
Thermodynamic study of the interaction of methotrexate, its metabolites, and new antifolates with thymidylate synthase: influence of FdUMP.
Topics: Calorimetry; Fluorodeoxyuridylate; Folic Acid Antagonists; Methotrexate; Thermodynamics; Thymidylate Synthase | 1990 |
A rapid, reliable, and convenient method for the purification of thymidylate synthase from amethopterin-resistant Lactobacillus casei.
Topics: Chromatography, Affinity; Chromatography, Agarose; Drug Resistance, Microbial; Electrophoresis; Fluorodeoxyuridylate; Kinetics; Lacticaseibacillus casei; Methotrexate; Protein Binding; Thymidylate Synthase | 1989 |
Sequential methotrexate/5-FU: FdUMP formation and TS inhibition in a transplantable rodent colon adenocarcinoma.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Deoxyuracil Nucleotides; Drug Interactions; Female; Fluorodeoxyuridylate; Fluorouracil; Kinetics; Male; Methotrexate; Neoplasm Transplantation; Rats; Rats, Inbred Strains; Thymidylate Synthase | 1986 |
The role of methotrexate and dihydrofolate polyglutamates in the enhancement of fluorouracil action by methotrexate.
Topics: Animals; Cell Line; Cell Survival; Drug Administration Schedule; Drug Therapy, Combination; Fluorodeoxyuridylate; Fluorouracil; Folic Acid; Folic Acid Antagonists; Leukemia L1210; Methotrexate; Mice; Polyglutamic Acid; Pteroylpolyglutamic Acids; Thymidylate Synthase | 1981 |
Enhancement of the incorporation of 5-fluorodeoxyuridylate into DNA of HL-60 cells by metabolic modulations.
Topics: Cell Line; Deoxyuracil Nucleotides; DNA Replication; DNA, Neoplasm; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Humans; Kinetics; Leukemia, Myeloid, Acute; Methotrexate; Thymidine; Tritium | 1983 |
Rate-limiting steps in the interactions of fluoropyrimidines and methotrexate.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; Deoxyuridine; DNA, Neoplasm; Drug Interactions; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Methotrexate; Mice; Neoplasm Proteins; RNA, Neoplasm; Thymidine Monophosphate | 1984 |
Use of secondary alpha-hydrogen isotope effects in reactions of pyrimidine nucleoside/nucleotide metabolism: thymidylate synthetase.
Topics: Carbon Radioisotopes; Drug Resistance, Microbial; Fluorodeoxyuridylate; Isotope Labeling; Kinetics; Lacticaseibacillus casei; Methotrexate; Methyltransferases; Structure-Activity Relationship; Thymidylate Synthase; Tritium | 1980 |
Fluorine-19 nuclear magnetic resonance characterization of ternary complexes of folate derivatives, 5-fluorodeoxyuridylate and Lactobacillus.
Topics: Aminopterin; Binding Sites; Deoxyuracil Nucleotides; Fluorodeoxyuridylate; Folic Acid; Folic Acid Antagonists; Lacticaseibacillus casei; Magnetic Resonance Spectroscopy; Methotrexate; Methyltransferases; Protein Binding; Structure-Activity Relationship; Tetrahydrofolates; Thymidylate Synthase | 1981 |
Sequential methotrexate and 5-fluorouracil: mechanisms of synergy.
Topics: Animals; Biotransformation; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Fluorodeoxyuridylate; Fluorouracil; Folic Acid; Humans; Methotrexate; Mice; Neoplasm Transplantation; Sarcoma, Experimental; Thymidylate Synthase; Time Factors | 1983 |
Addition of leucovorin in modulation of 5-fluorouracil with methotrexate: potentiating or reversing effect?
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Cell Division; Female; Fluorodeoxyuridylate; Fluorouracil; Humans; Leucovorin; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Tumor Cells, Cultured | 1995 |
Cross-resistance to antifolates in multidrug resistant cell lines with P-glycoprotein or multidrug resistance protein expression.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Division; Drug Resistance, Multiple; Fluorodeoxyuridylate; Fluorouracil; Folic Acid Antagonists; Gene Expression Regulation; Humans; Indoles; Isoindoles; Methotrexate; Peptide Synthases; Polymerase Chain Reaction; Quinazolines; RNA, Messenger; Thiophenes; Thymidylate Synthase; Tumor Cells, Cultured | 1997 |