Compounds > fluorine
Page last updated: 2024-08-22

fluorine and vigabatrin

fluorine has been researched along with vigabatrin in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pan, Y; Qiu, J; Silverman, RB1
Lu, H; Silverman, RB1
Groves, AP; Juncosa, JI; Silverman, RB; Xia, G1

Other Studies

3 other study(ies) available for fluorine and vigabatrin

ArticleYear
Design, synthesis, and biological activity of a difluoro-substituted, conformationally rigid vigabatrin analogue as a potent gamma-aminobutyric acid aminotransferase inhibitor.
    Journal of medicinal chemistry, 2003, Dec-04, Volume: 46, Issue:25

    Topics: 4-Aminobutyrate Transaminase; Amino Acids; Cyclopentanes; Drug Design; Fluorine; Molecular Conformation; Structure-Activity Relationship; Vigabatrin

2003
Fluorinated conformationally restricted gamma-aminobutyric acid aminotransferase inhibitors.
    Journal of medicinal chemistry, 2006, Dec-14, Volume: 49, Issue:25

    Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Aza Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cyclopentanes; Fluorine; Heptanes; Kinetics; Molecular Conformation; Stereoisomerism; Structure-Activity Relationship; Swine; Vigabatrin

2006
Probing the steric requirements of the γ-aminobutyric acid aminotransferase active site with fluorinated analogues of vigabatrin.
    Bioorganic & medicinal chemistry, 2013, Feb-15, Volume: 21, Issue:4

    Topics: 4-Aminobutyrate Transaminase; Anticonvulsants; Binding Sites; Catalytic Domain; Fluorine; gamma-Aminobutyric Acid; Molecular Docking Simulation; Vigabatrin

2013