fluorine has been researched along with organophosphonates in 46 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (43.48) | 18.7374 |
| 1990's | 1 (2.17) | 18.2507 |
| 2000's | 12 (26.09) | 29.6817 |
| 2010's | 11 (23.91) | 24.3611 |
| 2020's | 2 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Yount, RG | 1 |
| Bonte, FJ; Graham, KD; Moore, JG; Parkey, RW | 1 |
| Csopak, H; Fölsch, G; Lilja, H; Lindman, B | 1 |
| Fordham, EW; Ryan, WG; Shirazi, PH | 1 |
| Broomfield, CA; Hackley, BE; Morrisett, JD | 1 |
| Berry, WK; Davies, DR; Gordon, JJ | 1 |
| Danenberg, PV; Santi, DV; Satterly, P | 1 |
| Bautovich, GJ; Genant, HK; Harper, PV; Lathrop, KA; Singh, M | 1 |
| Henkin, RE; Quinn, JL; Thrupkaew, AK | 1 |
| Ackerhalt, RE; Bakshi, S; Blau, M; Sondel, JA | 1 |
| Chase, R; Gillam, IC; Tener, GM | 1 |
| Dorrington, KJ; Hofmann, T | 1 |
| Francis, MD; Tofe, AJ | 1 |
| Castronovo, FP; Miller, SW; Pendergrass, HP; Potsaid, MS | 1 |
| Mildvan, AS; Nowak, T | 1 |
| Jethi, RK; Wadkins, CL | 1 |
| Coult, DB; Howells, DJ | 1 |
| Jović, R; Milosević, M | 1 |
| Briney, GC; Fellman, JD; Hafner, LS | 1 |
| Berry, WK; Davies, DR | 1 |
| Lei, PS; Mensa-Wilmot, K; Morris, JC; Shen, TY; Zhai, HX | 1 |
| Berkowitz, DB; Bose, M; Doukov, T; Pfannenstiel, TJ | 1 |
| Kondo, H; Nishimura, S; Sawa, M | 1 |
| Guillín, JJ; Ojea, V; Quintela, JM; Ruiz, M | 1 |
| de Medina, P; Ingrassia, LS; Mulliez, ME | 1 |
| Aoki, J; Arai, H; Hama, K; Mills, GB; Prestwich, GD; Qian, L; Shimizu, K; Takanezawa, Y; Umezu-Goto, M; Xu, Y; Yu, S | 1 |
| Gajewiak, J; Jiang, G; Prestwich, GD; Qian, L; Xu, Y | 1 |
| Cao, Y; Fuchigami, T; Hidaka, A; Tajima, T | 1 |
| Figueroa, R; Molander, GA | 1 |
| Boojamra, CG; Cihlar, T; Douglas, J; Grant, D; Hui, H; Lin, KY; Mackman, RL; Petrakovsky, O; Prasad, V; Ray, AS | 1 |
| Boojamra, CG; Cihlar, T; Douglas, J; Grant, D; Kim, CU; Mackman, RL; Markevitch, DY; Prasad, V; Ray, AS | 1 |
| Fernández de Trocóniz, G; Ochoa de Retana, AM; Oyarzabal, J; Palacios, F; Pascual, S | 1 |
| Bhadury, PS; Chen, Z; Hu, D; Jin, L; Song, B; Xue, W; Yang, S; Zhang, S; Zhang, Y | 1 |
| Batra, VK; Beard, WA; Goodman, MF; Kashemirov, BA; McKenna, CE; Oertell, K; Olah, GA; Pedersen, LC; Shock, DD; Surya Prakash, GK; Upton, TG; Wilson, SH; Zibinsky, M | 1 |
| Makhaeva, GF; Nenajdenko, VG; Serebryakova, OG; Sokolov, VB; Sokolova, NV | 1 |
| Chang, CM; Chen, CH; Chung, TW; Huang, YL; Liao, CC; Liaw, SH; Lin, CH; Shaw, GC; Sun, CM; Tsay, YG | 1 |
| Babusis, D; Boojamra, CG; Brown, B; Feng, JY; Hui, H; Lee, SK; Mackman, RL; Parrish, JP; Ray, AS; Shih, IH | 1 |
| Angelovski, G; Baranyai, Z; Botta, M; Hagberg, GE; Kálmán, FK; Krenzer, A; Logothetis, NK; Placidi, MP; Rogerson, AK; Tóth, I | 1 |
| Beier, P; Beran, P; Opekar, S; Pohl, R; Rulíšek, L | 1 |
| Feng, Z; Min, QQ; Xiao, YL; Zhang, B; Zhang, X | 1 |
| Sirin, GS; Zhang, Y | 1 |
| Baxter, NJ; Bhattasali, D; Blackburn, GM; Bowler, MW; Cliff, MJ; Forget, SM; Jakeman, DL; Jin, Y; Pellegrini, E; Waltho, JP | 1 |
| Hong, JH; Kim, E; Kim, S | 1 |
| Bertani, F; Dalcanale, E; Pedrini, A | 1 |
| Aydın, EB; Sezgintürk, MK | 1 |
| Am Ende, CW; Bellenger, J; Butler, TW; Devraj Majmudar, J; Dutra, JK; Fisher, EL; Foley, TL; Huang, Z; Lachapelle, EA; Mahapatra, S; Ogilvie, K | 1 |
3 review(s) available for fluorine and organophosphonates
| Article | Year |
|---|---|
ATP analogs.
Topics: Adenosine Triphosphate; Binding Sites; Calcium; Chromium; Cobalt; Enzymes; Fluorescence; Fluorine; Formycins; Hydrogen-Ion Concentration; Magnesium; Manganese; Mercury; Organophosphonates; Phosphoric Acids; Ribose; Structure-Activity Relationship; Sulfhydryl Compounds; Sulfuric Acids; Thiocyanates | 1975 |
Bone scanning in evaluation of Paget's disease of bone.
Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Bone Neoplasms; Carcinoma, Bronchogenic; Diagnosis, Differential; Female; Fibrous Dysplasia of Bone; Fluorine; Fractures, Bone; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Organophosphonates; Osteitis Deformans; Osteoarthropathy, Primary Hypertrophic; Osteomyelitis; Plicamycin; Prostatic Neoplasms; Radioisotopes; Radionuclide Imaging; Sarcoma, Ewing; Technetium; Tuberculosis, Osteoarticular | 1974 |
New metabolically stabilized analogues of lysophosphatidic acid: agonists, antagonists and enzyme inhibitors.
Topics: Enzyme Inhibitors; Fluorine; Humans; Hydroxides; Lysophospholipids; Molecular Structure; Organophosphonates | 2005 |
43 other study(ies) available for fluorine and organophosphonates
| Article | Year |
|---|---|
Distributions of several agents useful in imaging myocardial infarcts.
Topics: Animals; Bone and Bones; Diphosphates; Dogs; Fluorine; Liver; Lung; Myocardial Infarction; Myocardium; Organophosphonates; Phosphates; Radioisotopes; Radionuclide Imaging; Technetium | 1975 |
19-F NMR studies of the binding of a fluorine-labeled phosphonate ion to E. coli alkaline phosphatase.
Topics: Alkaline Phosphatase; Binding Sites; Escherichia coli; Fluorine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Manganese; Organophosphonates; Protein Binding; Zinc | 1975 |
A new spin label specific for the active site of serine enzymes.
Topics: Acetylcholinesterase; Animals; Binding Sites; Brain Chemistry; Cattle; Cell Membrane; Chemical Phenomena; Chemistry; Chymotrypsin; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Erythrocytes; Fluorine; Free Radicals; Humans; Nerve Endings; Organophosphonates; Piperidines; Rats; Serine | 1969 |
Protection of animals against soman (1,2,2-trimethylpropyl methylphosphono-fluoridate) by pretreatment with some other organophosphorus compounds, followed by oxime and atropine.
Topics: Amitriptyline; Animals; Atropine; Bromides; Carbamates; Cholinesterase Inhibitors; Diphosphates; Drug Antagonism; Female; Fluorine; Guinea Pigs; Hydroxamic Acids; Isoflurophate; Lethal Dose 50; Nitrates; Nitrophenols; Nitroso Compounds; Organophosphonates; Organophosphorus Compounds; Orphenadrine; Oximes; Parasympatholytics; Physostigmine; Poisoning; Pyridinium Compounds; Rabbits; Rats; Salicylates; Scopolamine; Species Specificity; Sulfonic Acids; Sulfuric Acids; Thiazoles; Time Factors | 1971 |
Phenylalanyl transfer ribonucleic acid synthetase from Escherichia coli. Reaction parameters and order of substrate addition.
Topics: Acylation; Adenosine; Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Amino Alcohols; Carbon Isotopes; Catalysis; Diphosphates; Escherichia coli; Ethanol; Fluorine; Kinetics; Magnesium; Models, Chemical; Nucleosides; Organophosphonates; Oxidation-Reduction; Periodic Acid; Phenylalanine; Phosphorus Isotopes; Protein Binding; RNA, Transfer; Sodium Chloride; Structure-Activity Relationship | 1971 |
Bone-seeking radionuclides: an in vivo study of factors affecting skeletal uptake.
Topics: Albumins; Animals; Autoradiography; Bone and Bones; Cerium Isotopes; Femur; Fluorine; Humans; Indium; Isotopes; Knee; Male; Organophosphonates; Osteogenesis; Radioisotopes; Radionuclide Imaging; Rats; Regional Blood Flow; Rickets; Strontium Radioisotopes; Technetium; Tibia; Tin; Vitamin D; Vitamin D Deficiency | 1974 |
False negative bone scans in disseminated metastatic disease.
Topics: Adenocarcinoma; Aged; Bone Diseases; Bone Neoplasms; Breast Neoplasms; Carcinoma; False Negative Reactions; Female; Fluorine; Humans; Lumbar Vertebrae; Male; Middle Aged; Neoplasm Metastasis; Organophosphonates; Pelvis; Prostatic Neoplasms; Radiography; Radioisotopes; Radionuclide Imaging; Ribs; Technetium; Thoracic Vertebrae | 1974 |
A comparative study of three 99mTc-labeled phosphorus compounds and 18F-fluoride for skeletal imaging.
Topics: Animals; Bone and Bones; Bone Neoplasms; Fluorides; Fluorine; Freeze Drying; Humans; Kidney; Liver; Lung; Male; Muscles; Neoplasm Metastasis; Organophosphonates; Phosphates; Rabbits; Radioisotopes; Radionuclide Imaging; Spleen; Technetium | 1974 |
Changes in levels of amino acid acceptors in tRNA from Escherichia coli grown under various conditions.
Topics: Amino Acyl-tRNA Synthetases; Aminobutyrates; Carbon Radioisotopes; Chromatography, DEAE-Cellulose; Densitometry; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Fluorine; Mutation; Organophosphonates; Phenylalanine; RNA, Bacterial; RNA, Transfer; Spectrophotometry, Ultraviolet; Temperature; Threonine; Time Factors; Transfer RNA Aminoacylation; Tyrosine; Valine | 1974 |
Effects of ionic strength on the circular dichroism spectrum of chymotrypsin.
Topics: Acetates; Chemical Phenomena; Chemistry; Chlorides; Chymotrypsin; Chymotrypsinogen; Circular Dichroism; Fluorine; Isoleucine; Kinetics; Lithium; Macromolecular Substances; Nitric Oxide; Organophosphonates; Osmolar Concentration; Phosphoric Acids; Sodium; Sodium Chloride; Tryptophan; Ultracentrifugation; Ultraviolet Rays | 1973 |
Optimization of the ratio of stannous tin: ethane-1-hydroxy-1, 1-diphosphonate for bone scanning with 99mTc-pertechnetate.
Topics: Animals; Bone and Bones; Female; Fluorides; Fluorine; Organophosphonates; Radioisotopes; Radionuclide Imaging; Rats; Technetium | 1974 |
Technetium 99m labeled diphosphonate bone scanning in Paget's disease.
Topics: Bone and Bones; Fluorine; Humans; Injections, Intravenous; Organophosphonates; Osteitis Deformans; Radioisotopes; Radionuclide Imaging; Technetium; Time Factors | 1974 |
Nuclear magnetic resonance studies of the function of potassium in the mechanism of pyruvate kinase.
Topics: Animals; Binding Sites; Deuterium; Fluorine; Glycolates; Lactates; Magnetic Resonance Spectroscopy; Manganese; Methanol; Muscles; Organophosphonates; Phosphoenolpyruvate; Phosphoric Acids; Potassium; Protein Binding; Protein Conformation; Pyruvate Kinase; Pyruvates; Rabbits; Stereoisomerism; Structure-Activity Relationship | 1972 |
Studies of the mechanism of biological calcification. II. Evidence for a multi-step mechanism of calcification by tendon matrix.
Topics: Acetates; Animals; Calcification, Physiologic; Calcium; Calcium Isotopes; Catalysis; Collagen; Fluorine; Magnesium; Methylation; Organophosphonates; Phosphates; Phosphorus Isotopes; Tendons | 1971 |
Ions of the rare earths as possible reactivators of acetylcholinesterase inhibited by some organophosphorus compounds.
Topics: Acetylcholinesterase; Animals; Catalysis; Cattle; Chemical Phenomena; Chemistry; Cholinesterase Inhibitors; Enzyme Activation; Erythrocytes; Fluorine; Insecticides; Lanthanum; Organophosphate Poisoning; Organophosphonates; Organophosphorus Compounds; Phosphorus Isotopes; Poisoning; Pralidoxime Compounds; Sulfonic Acids; Yttrium | 1971 |
Inhibitory action of soman and some cholinolytics on the uptake of oxygen in the brain of rats and mice.
Topics: Animals; Atropine; Benactyzine; Brain; Cerebral Cortex; Cholinesterase Inhibitors; Cyclopentanes; Esters; Fluorine; Male; Medulla Oblongata; Mice; Organophosphonates; Oxygen Consumption; Parasympatholytics; Rats | 1970 |
Cyclohexyl alkylphosphonofluoridates.
Topics: Cyclohexanes; Fluorine; Organophosphonates | 1970 |
The use of carbamates and atropine in the protection of animals against poisoning by 1,2,2-trimethylpropyl methylphosphonofluoridate.
Topics: Animals; Atropine; Carbamates; Chickens; Cholinesterase Inhibitors; Dogs; Esters; Female; Fluorine; Guinea Pigs; Male; Mice; Neostigmine; Organophosphate Poisoning; Organophosphonates; Physostigmine; Poisoning; Pyridinium Compounds; Rabbits; Rats; Species Specificity; Time Factors | 1970 |
Inhibition of GPI phospholipase C from Trypanosoma brucei by fluoro-inositol dodecylphosphonates.
Topics: Animals; Dose-Response Relationship, Drug; Fluorine; Glycosylphosphatidylinositol Diacylglycerol-Lyase; Inositol; Models, Chemical; Organophosphonates; Organophosphorus Compounds; Phosphatidylinositol Diacylglycerol-Lyase; Structure-Activity Relationship; Trypanosoma brucei brucei; Type C Phospholipases | 1998 |
alpha-fluorinated phosphonates as substrate mimics for glucose 6-phosphate dehydrogenase: the CHF stereochemistry matters.
Topics: Crystallography, X-Ray; Fluorine; Glucose-6-Phosphate; Glucosephosphate Dehydrogenase; Kinetics; Leuconostoc; Models, Molecular; Molecular Conformation; Organophosphonates; Stereoisomerism; Substrate Specificity | 2000 |
Encounter with unexpected collagenase-1 selective inhibitor: switchover of inhibitor binding pocket induced by fluorine atom.
Topics: Amides; Binding Sites; Collagenases; Enzyme Inhibitors; Fluorine; Humans; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Models, Molecular; Organophosphonates; Protein Binding; Structure-Activity Relationship; Substrate Specificity | 2002 |
Stereoselective synthesis of alpha-monofluorinated phosphonate mimetics of naturally occurring phosphoserine and phosphothreonine, via electrophilic fluorination of lithiated bis-lactim ethers.
Topics: Crystallography, X-Ray; Ethers; Fluorine; Indicators and Reagents; Lactams; Organophosphonates; Phosphoserine; Phosphothreonine; Stereoisomerism | 2002 |
Synthesis of the first stable phosphonamide transition state analogue.
Topics: Acylation; Amides; Amines; Amino Acids; Anti-Bacterial Agents; Drug Design; Esters; Fluorine; Molecular Conformation; Organophosphonates; Organophosphorus Compounds; Peptide Hydrolases; Stereoisomerism | 2003 |
Structure-activity relationships of fluorinated lysophosphatidic acid analogues.
Topics: Animals; Calcium; Cell Line; Cell Line, Tumor; Chemotaxis; Fluorine; Humans; Insecta; Ligands; Lysophospholipids; Mitogen-Activated Protein Kinase Kinases; Organophosphonates; Phosphoric Monoester Hydrolases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Lysophosphatidic Acid; Stereoisomerism; Structure-Activity Relationship | 2005 |
Electrochemical partial fluorination of organic compounds. 80. Synthesis of cyclic alpha-arylthio-alpha-monofluorophosphonate esters.
Topics: Cyclization; Electrochemistry; Esters; Fluorine; Models, Chemical; Molecular Structure; Organophosphonates | 2005 |
Synthesis of unsaturated organotrifluoroborates via Wittig and Horner-Wadsworth-Emmons olefination.
Topics: Alkenes; Borates; Fluorine; Magnetic Resonance Spectroscopy; Molecular Structure; Organophosphonates; Potassium | 2006 |
Synthesis and anti-HIV activity of 2'-fluorine modified nucleoside phosphonates: analogs of GS-9148.
Topics: Anti-HIV Agents; Fluorine; Guanosine; Humans; Molecular Structure; Nucleosides; Organophosphonates; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Zidovudine | 2008 |
Synthesis and anti-HIV activity of GS-9148 (2'-Fd4AP), a novel nucleoside phosphonate HIV reverse transcriptase inhibitor.
Topics: Anti-HIV Agents; DNA, Mitochondrial; Fluorine; Guanosine; HIV Reverse Transcriptase; Humans; Molecular Structure; Nucleosides; Organophosphonates; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Zidovudine | 2008 |
Synthesis of fluoroalkylated beta-aminophosphonates and pyridines from primary beta-enaminophosphonates.
Topics: Alkylation; Fluorine; Magnetic Resonance Spectroscopy; Organophosphonates; Pyridines; Spectrometry, Mass, Electrospray Ionization | 2008 |
An effective route to fluorine containing asymmetric alpha-aminophosphonates using chiral Bronsted acid catalyst.
Topics: Acids; Acrolein; Catalysis; Fluorides; Fluorine; Imines; Molecular Structure; Organophosphonates; Phosphites; Thermodynamics | 2009 |
Synthesis and biological evaluation of fluorinated deoxynucleotide analogs based on bis-(difluoromethylene)triphosphoric acid.
Topics: Crystallography, X-Ray; DNA; Fluorine; Hydrogen Bonding; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Organophosphonates; RNA | 2010 |
Synthesis and testing of trifluoromethyl-containing phosphonate-peptide conjugates as inhibitors of serine hydrolases.
Topics: Carboxylesterase; Catalysis; Cholinesterase Inhibitors; Click Chemistry; Enzyme Activation; Fluorine; Inhibitory Concentration 50; Molecular Structure; Organophosphonates; Peptides; Serine Proteinase Inhibitors | 2011 |
Qualitative analysis of the fluorophosphonate-based chemical probes using the serine hydrolases from mouse liver and poly-3-hydroxybutyrate depolymerase (PhaZ) from Bacillus thuringiensis.
Topics: Animals; Bacillus thuringiensis; Blotting, Western; Carboxylic Ester Hydrolases; Chemistry Techniques, Analytical; Electrophoresis, Polyacrylamide Gel; Fluorine; Liver; Mass Spectrometry; Mice; Molecular Probes; Organophosphonates; Serine Proteases | 2012 |
Evaluation of 2'-α-fluorine modified nucleoside phosphonates as potential inhibitors of HCV polymerase.
Topics: Antiviral Agents; Cell Line; DNA-Directed RNA Polymerases; Drug Evaluation, Preclinical; Fluorine; Hepacivirus; Humans; Organophosphonates; Ribonucleosides; Virus Replication | 2013 |
Aryl-phosphonate lanthanide complexes and their fluorinated derivatives: investigation of their unusual relaxometric behavior and potential application as dual frequency 1H/19F MRI probes.
Topics: Fluorine; Gadolinium; Lanthanoid Series Elements; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Organophosphonates | 2013 |
Diethyl fluoronitromethylphosphonate: synthesis and application in nucleophilic fluoroalkyl additions.
Topics: Aldehydes; Alkylation; Fluorine; Halogenation; Ketones; Nitro Compounds; Organophosphonates; Stereoisomerism; Sulfones | 2014 |
Palladium-catalyzed difluoroalkylation of aryl boronic acids: a new method for the synthesis of aryldifluoromethylated phosphonates and carboxylic acid derivatives.
Topics: Boronic Acids; Carboxylic Acids; Catalysis; Electron Transport; Electrons; Fluorine; Organophosphonates; Palladium | 2014 |
How is acetylcholinesterase phosphonylated by soman? An ab initio QM/MM molecular dynamics study.
Topics: Acetylcholinesterase; Fluorine; Molecular Dynamics Simulation; Molecular Structure; Organophosphonates; Quantum Theory; Serine; Soman | 2014 |
α-Fluorophosphonates reveal how a phosphomutase conserves transition state conformation over hexose recognition in its two-step reaction.
Topics: Bacterial Proteins; Catalysis; Crystallography, X-Ray; Fluorine; Glucose-6-Phosphate; Glucosephosphates; Hexoses; Isomerism; Kinetics; Lactococcus lactis; Magnesium; Models, Molecular; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Organophosphonates; Phosphoglucomutase; Protein Conformation; Recombinant Proteins; Static Electricity; Thermodynamics | 2014 |
Synthesis and antiretroviral activity of novel 4'-fluoro-5'-deoxyphosphonic acid carbocyclic nucleoside analogs.
Topics: Acids, Carbocyclic; Anti-HIV Agents; Drug Design; Fluorine; Glyceraldehyde; Guanine; HIV-1; Organophosphonates; Purine Nucleotides; Structure-Activity Relationship | 2014 |
Fluorinated Tetraphosphonate Cavitands.
Topics: Calixarenes; Cations; Ethers, Cyclic; Fluorine; Halogenation; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Molecular Structure; Organophosphonates; Phenylalanine; Resorcinols; Sarcosine | 2018 |
Ultrasensitive detection of interleukin 1α using 3-phosphonopropionic acid modified FTO surface as an effective platform for disposable biosensor fabrication.
Topics: Antibodies, Immobilized; Biosensing Techniques; Disposable Equipment; Fluorine; Humans; Interleukin-1alpha; Limit of Detection; Organophosphonates; Propionates; Saliva; Surface Properties; Tin Compounds | 2021 |
Fluorophosphonates on-Demand: A General and Simplified Approach toward Fluorophosphonate Synthesis.
Topics: Adipocytes; Fluorine; Humans; Organophosphonates; Polymers; Serine Endopeptidases; Solid-Phase Synthesis Techniques | 2021 |