Compounds > fluorine
Page last updated: 2024-08-22

fluorine and gamma-aminobutyric acid

fluorine has been researched along with gamma-aminobutyric acid in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Silverman, RB; Wang, Z1
Nikolic, D; Silverman, RB; Van Breemen, RB; Wang, Z; Yuan, H1
Groves, AP; Juncosa, JI; Silverman, RB; Xia, G1
Borisova, T; Dudarenko, M; Gerus, I; Haufe, G; Kukhar, V; Mironets, R; Pozdnyakova, N; Shaitanova, E1

Other Studies

4 other study(ies) available for fluorine and gamma-aminobutyric acid

ArticleYear
Syntheses and evaluation of fluorinated conformationally restricted analogues of GABA as potential inhibitors of GABA aminotransferase.
    Bioorganic & medicinal chemistry, 2006, Apr-01, Volume: 14, Issue:7

    Topics: 4-Aminobutyrate Transaminase; Animals; Brain; Enzyme Inhibitors; Fluorine; gamma-Aminobutyric Acid; Molecular Conformation; Stereoisomerism; Structure-Activity Relationship; Swine

2006
(+/-)-(1S,2R,5S)-5-Amino-2-fluorocyclohex-3-enecarboxylic acid. A potent GABA aminotransferase inactivator that irreversibly inhibits via an elimination-aromatization pathway.
    Biochemistry, 2006, Dec-05, Volume: 45, Issue:48

    Topics: 4-Aminobutyrate Transaminase; Amino Acids, Cyclic; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Enzyme Activation; Enzyme Inhibitors; Fluorine; gamma-Aminobutyric Acid; Molecular Structure

2006
Probing the steric requirements of the γ-aminobutyric acid aminotransferase active site with fluorinated analogues of vigabatrin.
    Bioorganic & medicinal chemistry, 2013, Feb-15, Volume: 21, Issue:4

    Topics: 4-Aminobutyrate Transaminase; Anticonvulsants; Binding Sites; Catalytic Domain; Fluorine; gamma-Aminobutyric Acid; Molecular Docking Simulation; Vigabatrin

2013
Synthesis of new fluorinated analogs of GABA, Pregabalin bioisosteres, and their effects on [(3)H]GABA uptake by rat brain nerve terminals.
    Bioorganic & medicinal chemistry, 2015, Aug-01, Volume: 23, Issue:15

    Topics: Animals; Brain; Fluorine; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Male; Pregabalin; Rats; Rats, Wistar; Synaptosomes; Tritium

2015