fluorine has been researched along with deoxycytidine in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (23.53) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 7 (41.18) | 29.6817 |
| 2010's | 3 (17.65) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Eifinger, FF; Köhler, F | 1 |
| Brox, LW; Hendler, SS; LePage, GA; Shannahoff, DH | 1 |
| Omori, K; Sasaki, H | 1 |
| Cooper, GM; Greer, S | 1 |
| Edzes, HT; Noordhuis, P; Peters, GJ; Vermorken, JB | 1 |
| Hansen, HH; Kristjansen, PE; Quistorff, B; Spang-Thomsen, M | 1 |
| Cheng, YC; Chu, CK; Chun, BK; Schinazi, RF | 1 |
| Blackstock, AW; Case, LD; Hess, SM; Lightfoot, H; Mitchell, BS; Mukherji, SK; Swarts, SG; Tepper, JE | 1 |
| Heerschap, A; Kamm, YJ; Klomp, DW; Punt, CJ; van Laarhoven, HW | 1 |
| Chung, YL; Griffiths, JR; Harris, AL; Judson, IR; Leach, MO; Leek, R; Stubbs, M; Troy, H | 1 |
| Chu, CK; Du, J; Hassan, AE; Lostia, S; Ma, T; McBrayer, TR; Otto, MJ; Pankiewicz, KW; Patterson, SE; Schinazi, RF; Shi, J; Stuyver, LJ; Tharnish, PM; Watanabe, KA | 1 |
| Heerschap, A; Kamm, Y; Klomp, D; Scheenen, T; van Laarhoven, H | 1 |
| Chun, BK; Cleary, D; Du, J; Khan, N; Rachakonda, S; Ross, BS; Shi, J; Sofia, MJ; Stec, W; Wang, P | 1 |
| Bapiro, TE; Cook, N; Frese, KK; Goldgraben, MA; Griffiths, JR; Jacobetz, MA; Jodrell, DI; Madhu, B; Olive, KP; Richards, FM; Smith, DM; Tuveson, DA | 1 |
| Brown, K; Dixey, M; Linclau, B; Weymouth-Wilson, A | 1 |
| Cavaliere, A; Probst, KC; Slusarczyk, M; Westwell, AD | 1 |
| Carell, T; Kaminska, E; Korytiaková, E; Ponkkonen, E; Schelter, F; Schiffers, S; Schön, A | 1 |
1 review(s) available for fluorine and deoxycytidine
| Article | Year |
|---|---|
Fluorinated nucleosides as an important class of anticancer and antiviral agents.
Topics: Antineoplastic Agents; Antiviral Agents; Deoxycytidine; Fluorine; Fluorouracil; Gemcitabine; HIV; Neoplasms; Nucleoside Transport Proteins; Nucleosides; Positron-Emission Tomography | 2017 |
16 other study(ies) available for fluorine and deoxycytidine
| Article | Year |
|---|---|
[Comparative teratological studies with organic fluroine compounds, their bases and amines].
Topics: Abnormalities, Drug-Induced; Amines; Animals; Deoxycytidine; Female; Fluorides; Fluorides, Topical; Fluorine; Fluorouracil; Mice; Pregnancy | 1977 |
Studies on the growth inhibition and metabolism of 2'-deoxy-2'-fluorocytidine in cultured human lymphoblasts.
Topics: Carbon Radioisotopes; Cell Division; Cell Line; Cells, Cultured; Cytidine; Deoxycytidine; Deoxyribonucleosides; DNA, Neoplasm; Fluorine; Humans; Leukemia, Lymphoid; Tritium | 1974 |
The influence of single or fractionated doses of 5-fluoro-2'-deoxycytidine teratogenicity in mice.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Deoxycytidine; Deoxyribonucleosides; Ectromelia; Female; Fetal Death; Fetus; Fluorine; Gestational Age; Maternal-Fetal Exchange; Mice; Mice, Inbred ICR; Pregnancy | 1973 |
The effect of inhibition of cytidine deaminase by tetrahydrouridine on the utilization of deoxycytidine and 5-bromodeoxycytidine for deoxyribonucleic acid synthesis.
Topics: Adenocarcinoma; Aminohydrolases; Animals; Bone Marrow; Bromine; Cytidine; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; DNA; DNA, Neoplasm; Female; Fluorine; Intestine, Small; Lymphoma; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasms, Experimental; Spleen; Testis; Tritium; Uridine | 1973 |
Determination of the antimetabolite Gemcitabine (2',2'-difluoro-2'-deoxycytidine) and of 2',2'-difluoro-2'-deoxyuridine by 19F nuclear magnetic resonance spectroscopy.
Topics: Antimetabolites, Antineoplastic; Deoxycytidine; Floxuridine; Fluorine; Gemcitabine; Humans; Magnetic Resonance Spectroscopy | 1993 |
Intratumoral pharmacokinetic analysis by 19F-magnetic resonance spectroscopy and cytostatic in vivo activity of gemcitabine (dFdC) in two small cell lung cancer xenografts.
Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Small Cell; Deoxycytidine; Fluorine; Gemcitabine; Humans; Lung Neoplasms; Magnetic Resonance Spectroscopy; Mice; Mice, Nude; Neoplasm Transplantation | 1993 |
Synthesis of 2',3'-dideoxy-3'-fluoro-L-ribonucleosides as potential antiviral agents from D-sorbitol.
Topics: Antiviral Agents; Deoxycytidine; Dideoxynucleosides; Fluorine; Hepatitis B virus; Sorbitol; Stereoisomerism | 2000 |
Tumor uptake and elimination of 2',2'-difluoro-2'-deoxycytidine (gemcitabine) after deoxycytidine kinase gene transfer: correlation with in vivo tumor response.
Topics: Animals; Cell Division; Chromatography, High Pressure Liquid; Cytidine Triphosphate; Deoxycytidine; Deoxycytidine Kinase; Female; Fluorine; Gemcitabine; Gene Expression Regulation, Enzymologic; Gene Transfer Techniques; HT29 Cells; Humans; Magnetic Resonance Spectroscopy; Mice; Mice, Nude; Neoplasms, Experimental; Xenograft Model Antitumor Assays | 2001 |
In vivo monitoring of capecitabine metabolism in human liver by 19fluorine magnetic resonance spectroscopy at 1.5 and 3 Tesla field strength.
Topics: Aged; Antimetabolites, Antineoplastic; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Female; Floxuridine; Fluorine; Fluorouracil; Humans; Liver; Liver Neoplasms; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prodrugs | 2003 |
Noninvasive measurements of capecitabine metabolism in bladder tumors overexpressing thymidine phosphorylase by fluorine-19 magnetic resonance spectroscopy.
Topics: Animals; Antimetabolites, Antineoplastic; Capecitabine; Cell Line, Tumor; Deoxycytidine; DNA, Complementary; Fluorine; Fluorouracil; Humans; Immunohistochemistry; Magnetic Resonance Spectroscopy; Mice; Mice, Nude; Phantoms, Imaging; Temperature; Thymidine Phosphorylase; Time Factors; Urinary Bladder Neoplasms | 2004 |
Synthesis and in vitro anti-HCV activity of beta-D- and 1-2'-deoxy-2'-fluororibonucleosides.
Topics: Animals; Antiviral Agents; Cattle; Cell Line; Chemistry, Pharmaceutical; Deoxycytidine; Diarrhea Viruses, Bovine Viral; Drug Design; Fluorides; Fluorine; Hepacivirus; Humans; Hydrofluoric Acid; In Vitro Techniques; Liver; Models, Chemical; Molecular Biology; Potassium Compounds; Pyrimidine Nucleosides; Ribonucleosides; RNA; RNA, Ribosomal; Stereoisomerism | 2005 |
Quantitative 19F MR spectroscopy at 3 T to detect heterogeneous capecitabine metabolism in human liver.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Fluorine; Fluorouracil; Humans; Liver; Magnetic Resonance Spectroscopy | 2007 |
An efficient and diastereoselective synthesis of PSI-6130: a clinically efficacious inhibitor of HCV NS5B polymerase.
Topics: Antiviral Agents; Carbon; Chemistry, Organic; Chemistry, Pharmaceutical; Chromatography; Deoxycytidine; Drug Design; Fluorine; Glyceraldehyde; Glycosylation; Lactones; Models, Chemical; Phosphoranes; Stereoisomerism; Viral Nonstructural Proteins | 2009 |
A novel method for quantification of gemcitabine and its metabolites 2',2'-difluorodeoxyuridine and gemcitabine triphosphate in tumour tissue by LC-MS/MS: comparison with (19)F NMR spectroscopy.
Topics: Animals; Antineoplastic Agents; Calibration; Cytidine Triphosphate; Deoxycytidine; Disease Models, Animal; Floxuridine; Fluorine; Gemcitabine; Humans; Magnetic Resonance Spectroscopy; Mice; Reference Standards; Tandem Mass Spectrometry | 2011 |
The synthesis of gemcitabine.
Topics: Carbohydrates; Deoxycytidine; Fluorine; Gemcitabine; Halogenation; Humans; Molecular Structure; Neoplasms; Stereoisomerism | 2014 |
Analysis of an Active Deformylation Mechanism of 5-Formyl-deoxycytidine (fdC) in Stem Cells.
Topics: Animals; Cell Line; Chromatography, High Pressure Liquid; Deoxycytidine; Dioxygenases; Fluorine; Humans; Isomerism; Mice; Oxidation-Reduction; Stem Cells; Tandem Mass Spectrometry | 2020 |