Page last updated: 2024-08-23

fluorides and methoxyflurane

fluorides has been researched along with methoxyflurane in 114 studies

Research

Studies (114)

TimeframeStudies, this research(%)All Research%
pre-1990106 (92.98)18.7374
1990's5 (4.39)18.2507
2000's1 (0.88)29.6817
2010's0 (0.00)24.3611
2020's2 (1.75)2.80

Authors

AuthorsStudies
Ivanetich, KM; Lucas, SA; Marsh, JA1
Hays, RM; Levine, RD; Levine, SD; Worthington, RE1
Bell, LE; Hitt, BA; Mazze, RI1
Cumming, M; Palahniuk, RJ2
Bonetti, E; Bonora, M; Cetrullo, C; Novello, F1
Larsen, ER; Malek, RS; McCarty, LP1
Caughey, GH; Kosek, JC; Mazze, RI; Rice, SA1
Brunson, DB; McGrath, CJ; Stowe, CM1
Dahlgren, BE2
Beard, AG; Clark, RB; Thompson, DS1
Beppu, WJ; Hitt, BA; Mazze, RI1
Cummings, JR; Jaramillo, J1
Inoue, T; Kou, S; Okuaki, A; Suzuki, M1
Hitt, BA; Mazze, RI1
Sakai, T; Takaori, M1
Hadler, NM; Klemmer, PJ1
Arthaud, LE; Loomis, TA1
Carter, JR; Kauker, ML; North, WC; Roman, RJ1
Pedersoli, WM1
Barclay, DL; Beard, AG; Clark, RB; Thompson, DS1
Calimlim, JF; Freeman, RB; Kumazawa, T; Merin, RG; Samuelson, PN; Taves, DR1
Fiserova-Bergerova, V2
Authier, L; Brodeur, J; Côté, MG; Geadah, D; Paquin, P; Yamauchi, M1
Mazze, RI2
Batra, MS; Dunkley, M; McCaughey, TJ; Thomson, C1
Peterson, C; Stoelting, RK1
de Carlini, C; Weiss, V2
Madura, JA; Peterson, C; Stoelting, RK; Young, SR1
de Carlini, Ch; Weiss, V1
Beppu, WJ; Cook, TL; Hitt, BA; Kosek, JC; Mazze, RI1
Cousins, MJ; Greenstein, LR; Hitt, BA; Mazze, RI1
Fiserova-Bergerova, V; Holaday, DA; Yoshimura, N1
Adler, L; Brown, BR; Thompson, MF1
Ciarlone, AE; Fry, BW1
Liu, J1
London, RE; Perlman, ME; Selinsky, BS1
Eger, EI; Johnson, BH; Koblin, DD; Konopka, K; Waskell, L1
Conney, AH; Pantuck, CB; Pantuck, EJ1
Phythyon, JM; Shaheen, O; Shay, S; Sweetman, BJ; Uetrecht, J; Wood, AJ; Wood, M1
Ciarlone, AE; Coalson, BE; Fry, BW1
Cousins, MJ; Hall, PD; Ilsley, AH; Jenner, MA; Plummer, JL1
Creasser, C; Stoelting, RK1
Anderson, NB; Cascorbi, HF1
Coldwell, BB; Hirsch, GH; Pakuts, AP; Solomonraj, G1
Akera, T; Brody, TM; Dworin, JZ; Tobin, T1
Schuck, SL; Shulman, A1
Rosenberg, PH; Wahlström, T1
Cousins, MJ; Hitt, BA; Mazze, RI1
Cousins, MJ; Mazze, RI7
Cousins, MJ; Hitt, BA; Kosek, JC; Love, FV; Mazze, RI1
Mäkeläinen, A; Rosenberg, P1
Fleming, PJ; Murray, WJ1
Cousins, MJ; Kosek, JC; Mazze, RI3
Baur, O; Girard-Longhini, C; Roux, J; Turbellier, JM1
Garcia, DA; Hetrick, WD; Siker, ES; Wolfson, B1
Fry, BW; Merin, RG; Taves, DR1
Dobkin, AB; Levy, AA1
Hamilton, WF; Robertson, GS3
Wilson, J1
Barr, GA; Cousins, MJ; Kosek, JC; Mazze, RI2
Berman, ML; Bochantin, J; Hagler, K; Lowe, HJ1
Brechtelsbauer, H; Finsterer, U; Kramer, K; Prucksunand, P; Witzgall, H1
Clubb, RJ; Tobey, RE1
Van Dyke, RA; Wood, CL1
Barr, GA; Cousins, MJ; Hitt, BA; Kosek, JC; Mazze, RI1
Fry, BW; Taves, DR1
Shen, YW; Taves, DR1
Barr, GA; Cousins, MJ; Mazze, RI1
Creasser, CW; Krishna, G; Peterson, C; Stoelting, RK1
Bastron, RD; Kaloyanides, GJ1
Frascino, JA1
Cousins, MJ; Mazze, RI; Nishimura, TG1
Hodgkinson, A; Marshall, RW; Wilson, J1
Hook, JB1
Cousins, MJ; Mazze, RI; Trudell, JR1
Freeman, RB; Fry, BW; Gillies, AJ; Taves, DR2
Holaday, DA; Rudofsky, S; Treuhaft, PS1
Chenoweth, MB1
Ball, GL; Corbett, TH1
Cousins, MJ; Hall, P; Plummer, JL1
Van Dyke, RA1
Ciarlone, AE; Faircloth, RE; Fry, BW1
Poppers, PJ1
Baden, JM; Mazze, RI; Rice, SA1
Madelian, V; Warren, W1
Blitt, CD; Brown, BR; Gandolfi, AJ; Soltis, JJ1
Gonzales, J; Waskell, L1
Fleming, JT; Pedersoli, WM1
Hankins, DC; Kharasch, ED; Thummel, KE1
Kharasch, ED; Thummel, KE1
Bosch, T1
Kusume, Y1
NEAL, MJ; ROBSON, JM1
Allison, SJ; Chase, JG; Docherty, PD; Pons, D2

Reviews

7 review(s) available for fluorides and methoxyflurane

ArticleYear
Renal toxicity of anaesthetics: with specific reference to the nephrotoxicity of methoxyflurane.
    Canadian Anaesthetists' Society journal, 1973, Volume: 20, Issue:1

    Topics: Acid-Base Equilibrium; Acute Kidney Injury; Adjuvants, Anesthesia; Biotransformation; Enzyme Induction; Fluorides; Humans; Hydrogen-Ion Concentration; Kidney; Kidney Concentrating Ability; Methoxyflurane; Oxalates; Phenobarbital; Prospective Studies; Time Factors

1973
Biotransformation of enflurane (Ethrane) and isoflurane (Forane).
    International anesthesiology clinics, 1974,Summer, Volume: 12, Issue:2

    Topics: Anesthesia, Inhalation; Anesthetics; Animals; Biotransformation; Ethers; Fluorides; Half-Life; Halothane; Humans; Hydrocarbons, Fluorinated; Hydrocarbons, Halogenated; Kidney; Liver; Methoxyflurane

1974
Biotransformation of methoxyflurane.
    International anesthesiology clinics, 1974,Summer, Volume: 12, Issue:2

    Topics: Anesthesia, Inhalation; Animals; Biotransformation; Carbon Dioxide; Carbon Radioisotopes; Chemical and Drug Induced Liver Injury; Chlorine; Enzyme Induction; Fluorides; Fluorine; Humans; Kidney; Kidney Tubules, Proximal; Liver; Methoxyflurane; Microscopy, Electron; Mitochondrial Swelling; Oxalates; Pharmacogenetics; Radioisotopes; Rats

1974
Volatile anaesthetic metabolism and acute toxicity.
    Quarterly reviews on drug metabolism and drug interactions, 1982, Volume: 4, Issue:1

    Topics: Animals; Biotransformation; Dose-Response Relationship, Drug; Enflurane; Fluoride Poisoning; Fluorides; Halothane; Humans; Isoflurane; Kidney; Liver; Methoxyflurane; Methyl Ethers; Models, Biological

1982
Hepatic drug metabolism and anesthesia.
    Der Anaesthesist, 1980, Volume: 29, Issue:2

    Topics: Acute Kidney Injury; Anesthetics; Aryl Hydrocarbon Hydroxylases; Biphenyl Compounds; Carcinogens; Cytochrome P-450 Enzyme System; Enzyme Induction; Fluorides; Halothane; Humans; Liver; Methoxyflurane; Methylcholanthrene; Phenobarbital

1980
[Nephrotoxicity and fluoride from the viewpoint of the nephrologist].
    Der Anaesthesist, 1996, Volume: 45 Suppl 1

    Topics: Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Ethers; Fluorides; Humans; Kidney; Metabolic Clearance Rate; Methoxyflurane; Methyl Ethers; Rats; Rats, Inbred F344; Sevoflurane

1996
Serum fluoride levels in ambulance staff after commencement of methoxyflurane administration compared to meta-analysis results for the general public.
    International journal of occupational medicine and environmental health, 2021, Dec-13, Volume: 34, Issue:6

    Topics: Adult; Ambulances; Fluorides; Humans; Kidney; Methoxyflurane; Observational Studies as Topic

2021

Trials

3 trial(s) available for fluorides and methoxyflurane

ArticleYear
Serum cholinesterase activity following the use of methoxyflurane in obstetrics.
    Anesthesiology, 1977, Volume: 47, Issue:6

    Topics: Anesthesia, Obstetrical; Cesarean Section; Cholinesterases; Clinical Trials as Topic; Female; Fluorides; Humans; Methoxyflurane; Nitrous Oxide; Pregnancy

1977
Biodegradation of halothane, enflurane and methoxyflurane.
    British journal of anaesthesia, 1978, Volume: 50, Issue:8

    Topics: Adult; Aged; Anesthesia, Inhalation; Biotransformation; Enflurane; Female; Fluorides; Halothane; Humans; Male; Methoxyflurane; Methyl Ethers; Middle Aged; Time Factors

1978
Renal function after methoxyflurane and halothane anesthesia.
    JAMA, 1973, Feb-05, Volume: 223, Issue:6

    Topics: Adult; Analysis of Variance; Anesthesia, General; Blood Urea Nitrogen; Diuresis; Fluorides; Halothane; Hematocrit; Humans; Kidney; Male; Methoxyflurane; Oxalates; Potassium; Preanesthetic Medication; Sodium; Uric Acid

1973

Other Studies

104 other study(ies) available for fluorides and methoxyflurane

ArticleYear
Enflurane and methoxyflurane. Their interaction with hepatic cytochrome P-450 in vitro.
    Biochemical pharmacology, 1979, Mar-15, Volume: 28, Issue:6

    Topics: Animals; Cytochrome P-450 Enzyme System; Enflurane; Fluorides; In Vitro Techniques; Kinetics; Liver; Male; Methoxyflurane; Methyl Ethers; Metyrapone; Microsomes, Liver; NADP; Oxidation-Reduction; Proadifen; Rats

1979
Selective inhibition of osmotic water flow by general anesthetics to toad urinary bladder.
    The Journal of clinical investigation, 1976, Volume: 58, Issue:4

    Topics: Anesthetics; Animals; Anura; Biological Transport; Body Water; Cyclic AMP; Female; Fluorides; Halothane; Methohexital; Methoxyflurane; Osmosis; Permeability; Phenytoin; Urea; Urinary Bladder; Vasopressins

1976
The influence of age on the distribution, metabolism and excretion of methoxyflurane in Fischer 344 rats: a possible relationship to nephrotoxicity.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 195, Issue:1

    Topics: Aging; Anesthesia; Animals; Carbon Dioxide; Fluorides; Hydrogen-Ion Concentration; Kidney Diseases; Male; Methoxyflurane; Microsomes, Liver; Osmolar Concentration; Oxidoreductases; Oxygen; Rats; Rats, Inbred F344

1975
RNA-synthesis in rat kidneys after fluorinated anesthetics or inorganic fluoride administration.
    Experientia, 1979, Jan-15, Volume: 35, Issue:1

    Topics: Animals; Depression, Chemical; Enflurane; Fluorides; Halothane; Kidney; Kidney Diseases; Male; Methoxyflurane; Rats; RNA

1979
The effects of deuteration on the metabolism of halogenated anesthetics in the rat.
    Anesthesiology, 1979, Volume: 51, Issue:2

    Topics: Alanine Transaminase; Anesthetics; Animals; Bromides; Chemical Phenomena; Chemistry, Physical; Chloroform; Deuterium; Enflurane; Fluorides; Halothane; Male; Methoxyflurane; Oxidation-Reduction; Rats; Trifluoroacetic Acid

1979
Effect of phenytoin (DPH) treatment on methoxyflurane metabolism in rats.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 210, Issue:2

    Topics: Anesthetics; Animals; Drug Interactions; Enflurane; Ethers; Fluorides; Hydrocarbons, Fluorinated; In Vitro Techniques; Isoflurane; Kidney; Kinetics; Liver; Male; Methoxyflurane; Microsomes, Liver; Phenobarbital; Phenytoin; Rats

1979
Serum and urine inorganic fluoride concentrations and urine oxalate concentrations following methoxyflurane anesthesia in the dog.
    American journal of veterinary research, 1979, Volume: 40, Issue:2

    Topics: Anesthesia; Animals; Dogs; Female; Fluorides; Male; Methoxyflurane; Osmolar Concentration; Oxalates; Time Factors

1979
Fluoride concentrations in urine of delivery ward personnel following exposure to low concentrations of methoxyflurane.
    Journal of occupational medicine. : official publication of the Industrial Medical Association, 1979, Volume: 21, Issue:9

    Topics: Anesthesia, Obstetrical; Delivery, Obstetric; Environmental Exposure; Evaluation Studies as Topic; Female; Fluorides; Hospital Departments; Humans; Methoxyflurane; Obstetrics and Gynecology Department, Hospital; Occupational Medicine; Pregnancy; Sweden; Workforce

1979
Renal function in newborns and mothers exposed to methoxyflurane analgesia for labor and delivery.
    Anesthesiology, 1979, Volume: 51, Issue:5

    Topics: Anesthesia, Obstetrical; Blood Urea Nitrogen; Creatinine; Female; Fluorides; Humans; Infant, Newborn; Kidney; Labor, Obstetric; Methoxyflurane; Pregnancy; Uric Acid

1979
Metabolism of synthane: comparison with in vivo and in vitro defluorination of other halogenated hydrocarbon anaesthetics.
    British journal of anaesthesia, 1979, Volume: 51, Issue:9

    Topics: Anesthesia, Inhalation; Anesthetics; Animals; Biotransformation; Enflurane; Ether; Ethyl Ethers; Fluorides; Halothane; Hydrocarbons, Fluorinated; In Vitro Techniques; Isoflurane; Male; Methoxyflurane; Microsomes, Liver; Rats

1979
Assessment of the anaesthetic and metabolic activities of dioxychlorane, a new halogenated volatile anaesthetic agent.
    British journal of anaesthesia, 1979, Volume: 51, Issue:11

    Topics: Anesthetics; Animals; Body Weight; Cerebral Cortex; Dioxolanes; Dioxoles; Drinking; Eating; Electroencephalography; Enflurane; Fluorides; Halothane; Male; Methoxyflurane; Rats; Urination

1979
[Inorganic fluoride concentration after methoxyflurane and halothane anesthesia].
    Masui. The Japanese journal of anesthesiology, 1977, Volume: 26, Issue:3

    Topics: Adult; Anesthesia, Inhalation; Female; Fluorides; Halothane; Humans; Male; Methoxyflurane; Middle Aged

1977
Effect of enzyme induction on nephrotoxicity of halothane-related compounds.
    Environmental health perspectives, 1977, Volume: 21

    Topics: Anesthetics; Animals; Biotransformation; Enflurane; Environmental Exposure; Enzyme Induction; Fluorides; Halothane; Humans; Isoflurane; Kidney Diseases; Methoxyflurane; Phenobarbital; Rats

1977
Urinary fluoride concentration in mothers and neonates after methoxyflurane-nitrous oxide analgesia during labour.
    Acta pharmaceutica Suecica, 1978, Volume: 15, Issue:3

    Topics: Anesthesia, Inhalation; Anesthesia, Obstetrical; Female; Fluorides; Humans; Infant, Newborn; Ions; Methoxyflurane; Nitrous Oxide; Pregnancy; Volatilization

1978
Subacute fluorosis: a consequence of abuse of an organofluoride anesthetic.
    Annals of internal medicine, 1978, Volume: 89, Issue:5 Pt 1

    Topics: Acute Disease; Adult; Bone and Bones; Chronic Disease; Female; Fluorides; Humans; Hypertension; Kidney Diseases; Methoxyflurane; Osteosclerosis; Periostitis; Substance-Related Disorders

1978
Methoxyflurane-induced nephrotoxicity: influence of food intake on some biochemical indicators of renal function in Fischer 344 rats.
    Toxicology and applied pharmacology, 1978, Volume: 45, Issue:3

    Topics: Animals; Body Weight; Diuresis; Drinking; Eating; Female; Fluorides; Kidney Diseases; Kidney Function Tests; Methoxyflurane; Osmolar Concentration; Oxygen; Rats; Rats, Inbred F344

1978
Renal tubular site of action of fluoride in Fischer 344 rats.
    Anesthesiology, 1977, Volume: 46, Issue:4

    Topics: Animals; Fluorides; Glomerular Filtration Rate; Kidney Tubules; Male; Mannitol; Methoxyflurane; Osmolar Concentration; Rats; Rats, Inbred F344; Sodium

1977
Serum fluoride concentration, renal, and hepatic function test results in dogs with methoxyflurane anesthesia.
    American journal of veterinary research, 1977, Volume: 38, Issue:7

    Topics: Anesthesia, Inhalation; Animals; Diuresis; Dogs; Female; Fluorides; Kidney; Kidney Function Tests; Liver; Liver Function Tests; Male; Methoxyflurane; Sulfobromophthalein

1977
Maternal and neonatal plasma inorganic fluoride levels after methoxyflurane analgesia for labor and delivery.
    Anesthesiology, 1976, Volume: 45, Issue:1

    Topics: Anesthesia, Inhalation; Anesthesia, Obstetrical; Blood Urea Nitrogen; Creatinine; Female; Fetal Blood; Fluorides; Humans; Infant, Newborn; Methoxyflurane; Pregnancy

1976
Toxicity following methoxyflurane anaesthesia. IV. The role of obesity and the effect of low dose anaesthesia on fluoride metabolism and renal function.
    Canadian Anaesthetists' Society journal, 1976, Volume: 23, Issue:5

    Topics: Anesthesia; Female; Fluorides; Humans; Kidney; Male; Meperidine; Methoxyflurane; Obesity; Tubocurarine; Uric Acid

1976
Fluoride in bone of rats anesthetized during gestation with enflurane or methoxyflurane.
    Anesthesiology, 1976, Volume: 45, Issue:5

    Topics: Anesthesia, Inhalation; Animals; Biotransformation; Bone and Bones; Enflurane; Female; Fetus; Fluorides; Gestational Age; Maternal-Fetal Exchange; Methoxyflurane; Methyl Ethers; Osteogenesis; Pregnancy; Rats

1976
Influence of phenobarbital pretreatment on methoxyflurane and sodium fluoride nephropathy in Fischer 344 Rats.
    Toxicology and applied pharmacology, 1976, Volume: 37, Issue:2

    Topics: Animals; Fluorides; Kidney Diseases; Male; Methoxyflurane; Phenobarbital; Rats; Rats, Inbred F344

1976
Methoxyflurane nephropathy.
    Environmental health perspectives, 1976, Volume: 15

    Topics: Age Factors; Animals; Child; Dose-Response Relationship, Drug; Fluorides; Gentamicins; Humans; Kidney Diseases; Kidney Tubules; Methoxyflurane; Oxalates; Rats

1976
Effect of methoxyflurane on renal concentrating power.
    Canadian Anaesthetists' Society journal, 1975, Volume: 22, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Creatinine; Dose-Response Relationship, Drug; Fasting; Female; Fluorides; Humans; Kidney Concentrating Ability; Male; Methoxyflurane; Middle Aged; Osmolar Concentration; Time Factors; Water-Electrolyte Balance

1975
Methoxyflurane anesthesia in pediatric patients: evaluation of anesthetic metabolism and renal function.
    Anesthesiology, 1975, Volume: 42, Issue:1

    Topics: Anesthesia, Inhalation; Child; Fluorides; Humans; Kidney; Methoxyflurane

1975
Placental transfer of fluoride during methoxyflurane anaesthesia for cesarean section.
    Experientia, 1975, Mar-15, Volume: 31, Issue:3

    Topics: Anesthesia, Obstetrical; Cesarean Section; Female; Fetus; Fluorides; Humans; Infant, Newborn; Maternal-Fetal Exchange; Methoxyflurane; Placenta; Pregnancy

1975
Anesthetic biotransformation and renal function in obese patients during and after methoxyflurane or halothane anesthesia.
    Anesthesiology, 1975, Volume: 42, Issue:4

    Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Inhalation; Biopsy, Needle; Biotransformation; Fatty Liver; Fluorides; Halothane; Humans; Kidney; Kidney Function Tests; Liver; Methoxyflurane; Nitrous Oxide; Obesity; Oxalates; Uric Acid

1975
Methyoxuflurane and serum fluoride concentrations during anaesthesia and postoperative renal function.
    Der Anaesthesist, 1975, Volume: 24, Issue:2

    Topics: Adult; Aged; Anesthesia, General; Anesthesia, Obstetrical; Blood Pressure; Creatinine; Female; Fluorides; Humans; Hysterectomy; Kidney; Metabolic Clearance Rate; Methoxyflurane; Middle Aged; Osmolar Concentration; Time Factors; Water-Electrolyte Balance

1975
Plasma fluoride levels following obstetrical use of methoxyflurane.
    Canadian Anaesthetists' Society journal, 1975, Volume: 22, Issue:3

    Topics: Adult; Anesthesia, Inhalation; Anesthesia, Obstetrical; Apgar Score; Cesarean Section; Dose-Response Relationship, Drug; Female; Fluorides; Humans; Infant, Newborn; Maternal-Fetal Exchange; Methoxyflurane; Pregnancy

1975
[Renal effects and metabolism of sevoflurane in Fisher 3444 rats: an in-vivo and in-vitro comparison with methoxyflurane].
    Anesthesiology, 1975, Volume: 43, Issue:1

    Topics: Anesthesia, Inhalation; Anesthetics; Animals; Biotransformation; Blood Urea Nitrogen; Dose-Response Relationship, Drug; Ethers; Fluorides; Hydrocarbons, Fluorinated; Kidney; Male; Methoxyflurane; Microsomes, Liver; Osmolar Concentration; Rats; Rats, Inbred F344; Sodium

1975
Metabolism and renal effects of enflurane in man.
    Anesthesiology, 1976, Volume: 44, Issue:1

    Topics: Animals; Blood Pressure; Enflurane; Fluorides; Humans; Infusions, Parenteral; Kidney; Male; Methoxyflurane; Methyl Ethers; Osmolar Concentration; Rats; Rats, Inbred F344

1976
Metabolism of methoxyflurane in man.
    Anesthesiology, 1976, Volume: 44, Issue:5

    Topics: Acetates; Adult; Anesthesia, Inhalation; Female; Fluorides; Fluorine; Humans; Male; Methoxyflurane; Middle Aged; Oxalates

1976
Kinetics of methoxyflurane biotransformation with reference to substrate inhibition.
    Anesthesiology, 1976, Volume: 44, Issue:5

    Topics: Anesthesia, Inhalation; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Enzyme Induction; Fluorides; In Vitro Techniques; Kinetics; Male; Methoxyflurane; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred F344

1976
Perdeuteration of methoxyflurane reduces production of fluorometabolites in mice.
    Research communications in chemical pathology and pharmacology, 1990, Volume: 69, Issue:2

    Topics: Animals; Body Weight; Fluorides; Kidney Diseases; Male; Methoxyflurane; Mice; Postural Balance; Reflex

1990
[The fluoride metabolism of fluorinated anesthetics in cardiopulmonary bypass operation].
    Zhonghua yi xue za zhi, 1988, Volume: 68, Issue:7

    Topics: Adolescent; Anesthesia, Inhalation; Cardiopulmonary Bypass; Child; Enflurane; Female; Fluorides; Halothane; Humans; Isoflurane; Male; Methoxyflurane

1988
In vivo nuclear magnetic resonance studies of hepatic methoxyflurane metabolism. II. A reevaluation of hepatic metabolic pathways.
    Molecular pharmacology, 1988, Volume: 33, Issue:5

    Topics: Animals; Dichloroacetic Acid; Fluorides; Liver; Magnetic Resonance Spectroscopy; Methoxyflurane; Oxalates; Rats

1988
I-653 resists degradation in rats.
    Anesthesia and analgesia, 1988, Volume: 67, Issue:6

    Topics: Anesthetics; Animals; Biotransformation; Desflurane; Drug Interactions; Ethanol; Fluorides; Halothane; Isoflurane; Methoxyflurane; Phenobarbital; Rats; Rats, Inbred Strains

1988
Effect of streptozotocin-induced diabetes in the rat on the metabolism of fluorinated volatile anesthetics.
    Anesthesiology, 1987, Volume: 66, Issue:1

    Topics: Anesthesia, Inhalation; Anesthetics; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Experimental; Enflurane; Fluorides; Halothane; Insulin; Isoflurane; Male; Methoxyflurane; Microsomes, Liver; Rats; Rats, Inbred F344

1987
The effect of cimetidine on anesthetic metabolism and toxicity.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:5

    Topics: Alanine Transaminase; Anesthesia, Inhalation; Animals; Biotransformation; Bromides; Cimetidine; Drug Interactions; Enflurane; Fluorides; Halothane; Liver; Male; Methoxyflurane; Oxygen; Rats; Rats, Inbred F344; Rats, Inbred Strains

1986
The effect of cimetidine on the formation of methoxyflurane fluorometabolites in mice.
    Research communications in chemical pathology and pharmacology, 1985, Volume: 49, Issue:2

    Topics: Animals; Cimetidine; Dose-Response Relationship, Drug; Drug Interactions; Fluorides; Liver Circulation; Male; Methoxyflurane; Mice; Mice, Inbred ICR

1985
Hepatic and renal effects of prolonged exposure of rats to 50 p.p.m. methoxyflurane.
    Acta pharmacologica et toxicologica, 1985, Volume: 57, Issue:3

    Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Fatty Liver; Fluorides; Halothane; Kidney Diseases; Male; Methoxyflurane; Organ Size; Rats; Rats, Inbred F344; Time Factors

1985
Serum inorganic fluoride concentrations during and after halothane, fluroxene, and methoxyflurane anesthesia in man.
    Anesthesiology, 1973, Volume: 39, Issue:5

    Topics: Adult; Aged; Ethers; Fluorides; Halothane; Humans; Methoxyflurane; Middle Aged; Nitrous Oxide; Preanesthetic Medication; Thiamylal; Time Factors

1973
Effects of methoxyflurane and two metabolites on sodium transport in the toad bladder.
    Anesthesiology, 1974, Volume: 40, Issue:4

    Topics: Animals; Biological Transport, Active; Biotransformation; Bufo marinus; Depression, Chemical; Edetic Acid; Fluorides; Kidney Failure, Chronic; Methoxyflurane; Oxalates; Sodium; Stimulation, Chemical; Urinary Bladder; Urine

1974
Editorial: Methoxyflurane nephrotoxicity.
    British medical journal, 1974, May-04, Volume: 2, Issue:5913

    Topics: Anesthesia; Enzyme Inhibitors; Fluorides; Humans; Kidney Diseases; Methoxyflurane; Oxalates

1974
Effects of methoxyflurane and inorganic fluoride on renal function.
    Research communications in chemical pathology and pharmacology, 1973, Volume: 6, Issue:3

    Topics: Aminohippuric Acids; Animals; Blood Urea Nitrogen; Carbon Radioisotopes; Fluorides; Gluconeogenesis; Glycerol; Kidney; Kidney Cortex; Kidney Function Tests; Kidney Tubules, Proximal; Male; Methoxyflurane; Niacinamide; Oxygen Consumption; Rats; Rats, Inbred Strains; Tetracycline; Time Factors

1973
Fluoride nephropathy: lack of direct involvement of renal ATPase.
    Canadian journal of physiology and pharmacology, 1974, Volume: 52, Issue:3

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Fluorides; Kidney; Kidney Diseases; Magnesium; Male; Methoxyflurane; Microsomes; Potassium; Rats; Rats, Inbred Strains; Sodium; Time Factors

1974
A study of the central action of flurothyl and methoxyflurane.
    The Australian journal of experimental biology and medical science, 1971, Volume: 49, Issue:5

    Topics: Animals; Bemegride; Central Nervous System; Central Nervous System Stimulants; Chemical Phenomena; Chemistry; Cycloheximide; Depression, Chemical; Ethers; Female; Fluorides; Hypnotics and Sedatives; Male; Methoxyflurane; Mice; Neurons; Pentobarbital; Pregnanediones; Reticular Formation; Stimulation, Chemical; Synapses; Trimethadione

1971
Renal and hepatic toxicity of methoxyflurane in combination with tetracycline or oxytetracycline treatment in rats.
    Acta pharmacologica et toxicologica, 1974, Volume: 34, Issue:1

    Topics: Alanine Transaminase; Anesthesia, Inhalation; Animals; Depression, Chemical; Diuresis; Drug Synergism; Ethanol; Female; Fluorides; Halothane; Injections, Intraperitoneal; Kidney; Liver; Methoxyflurane; Oxalates; Oxytetracycline; Rats; Tetracycline; Time Factors; Uric Acid; Vasopressins

1974
Effect of enzyme induction with phenobarbital on the in vivo and in vitro defluorination of isoflurane and methoxyflurane.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 190, Issue:3

    Topics: Animals; Enzyme Induction; Ethers; Fluorides; Fluorine; Hydrocarbons, Fluorinated; Male; Methoxyflurane; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Time Factors

1974
Letter: Methoxyflurane nephrotoxicity.
    British medical journal, 1974, Aug-24, Volume: 3, Issue:5929

    Topics: Animals; Disease Models, Animal; Enzyme Induction; Fluorides; Humans; Kidney Concentrating Ability; Kidney Diseases; Methoxyflurane; Sodium; Urine

1974
The etiology of methoxyflurane nephrotoxicity.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 190, Issue:3

    Topics: Animals; Fluorides; Kidney; Kidney Diseases; Kidney Tubules, Proximal; Liver; Male; Methoxyflurane; Microscopy, Electron; Mitochondria; Mitochondrial Swelling; Osmolar Concentration; Oxalates; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains

1974
The effects of halothane and methoxyflurane metabolites on lipolysis in vitro.
    Acta anaesthesiologica Scandinavica, 1974, Volume: 18, Issue:2

    Topics: Acetaldehyde; Acetates; Adipose Tissue; Animals; Dose-Response Relationship, Drug; Ethanol; Fatty Acids, Nonesterified; Fluorides; Glycerol; Halothane; Hydrocarbons, Fluorinated; In Vitro Techniques; Male; Methoxyflurane; Norepinephrine; Propranolol; Rats; Stimulation, Chemical

1974
Defluorination of methoxyflurane during anesthesia: comparison of man with other species.
    Anesthesiology, 1972, Volume: 37, Issue:6

    Topics: Anesthesia; Animals; Cattle; Dogs; Fluorides; Guinea Pigs; Haplorhini; Methoxyflurane; Mice; Rats

1972
The morphology and pathogenesis of nephrotoxicity following methoxyflurane (penthrane) anesthesia. An experimental model in rats.
    Laboratory investigation; a journal of technical methods and pathology, 1972, Volume: 27, Issue:6

    Topics: Acute Kidney Injury; Anesthesia, Inhalation; Animals; Disease Models, Animal; Fluoride Poisoning; Fluorides; Kidney Cortex; Kidney Tubules; Kidney Tubules, Proximal; Male; Methoxyflurane; Mitochondrial Swelling; Rats; Time Factors

1972
[Methoxyflurane and renal function].
    Cahiers d'anesthesiologie, 1972, Volume: 20, Issue:8

    Topics: Adult; Anesthesia, Inhalation; Fluoride Poisoning; Fluorides; Humans; Kidney Failure, Chronic; Male; Methoxyflurane

1972
Renal responses to "light" methoxyflurane anesthesia.
    Anesthesiology, 1973, Volume: 38, Issue:1

    Topics: Adult; Anesthesia, Inhalation; Blood Urea Nitrogen; Creatinine; Female; Fluorides; Halothane; Humans; Kidney; Male; Methoxyflurane; Middle Aged; Osmolar Concentration; Sodium; Time Factors

1973
Fluorometabolites of methoxyflurane: serum concentrations and renal clearances.
    Anesthesiology, 1973, Volume: 38, Issue:1

    Topics: Adolescent; Adult; Female; Fluorides; Humans; Kidney; Male; Methoxyflurane; Middle Aged; Time Factors; Urine

1973
Strain differences in metabolism and susceptibility to the nephrotoxic effects of methoxyflurane in rats.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 184, Issue:2

    Topics: Anesthesia, Inhalation; Animals; Blood Urea Nitrogen; Fluorides; Kidney; Kidney Diseases; Kidney Tubules, Proximal; Male; Methoxyflurane; Microscopy, Electron; Rats; Rats, Inbred Strains; Sodium; Time Factors

1973
Blood serum fluoride levels with methoxyflurane anaesthesia.
    Canadian Anaesthetists' Society journal, 1973, Volume: 20, Issue:1

    Topics: Anesthesia, Inhalation; Female; Fluorides; Halothane; Humans; Intubation, Intratracheal; Male; Methoxyflurane; Middle Aged; Nitrous Oxide; Preanesthetic Medication; Time Factors

1973
Methoxyflurane and renal function.
    British journal of anaesthesia, 1973, Volume: 45, Issue:1

    Topics: Chlorides; Colostomy; Creatinine; Fluorides; Halothane; Humans; Kidney; Kidney Function Tests; Methoxyflurane; Osmolar Concentration; Phenoperidine; Potassium; Sodium; Uric Acid; Urinary Catheterization

1973
Methoxyflurane in Caesarean section.
    British journal of anaesthesia, 1973, Volume: 45, Issue:2

    Topics: Anesthesia, Obstetrical; Cesarean Section; Female; Fluorides; Humans; Kidney; Methoxyflurane; Nitrous Oxide; Oxalates; Oxygen; Pregnancy; Umbilical Cord

1973
An animal model for combined methoxyflurane and gentamicin nephrotoxicity.
    British journal of anaesthesia, 1973, Volume: 45, Issue:4

    Topics: Anesthesia; Animals; Blood Urea Nitrogen; Drug Synergism; Fluorides; Gentamicins; Kidney; Kidney Diseases; Kidney Tubules, Proximal; Male; Methoxyflurane; Microscopy, Electron; Osmolar Concentration; Rats; Sodium

1973
Combined nephrotoxicity of gentamicin and methoxyflurane anaesthesia in man. A case report.
    British journal of anaesthesia, 1973, Volume: 45, Issue:4

    Topics: Anesthesia, Inhalation; Blood Urea Nitrogen; Body Weight; Creatinine; Drug Synergism; Fluorides; Gentamicins; Humans; Kidney Diseases; Male; Methoxyflurane; Middle Aged; Osmolar Concentration; Postoperative Complications; Uric Acid; Urine; Vasopressins; Water-Electrolyte Balance

1973
A comparison of the renal effects of isoflurane and methoxyflurane in Fischer 344 rats.
    Anesthesiology, 1973, Volume: 38, Issue:6

    Topics: Anesthesia, Inhalation; Anesthetics; Animals; Atmosphere Exposure Chambers; Carbon Dioxide; Chlorine; Dose-Response Relationship, Drug; Ethers; Fluorides; Fluorine; Hematuria; Hydrocarbons, Halogenated; Hydrogen-Ion Concentration; Kidney; Methods; Methoxyflurane; Osmolar Concentration; Oxygen; Rats; Rats, Inbred F344; Time Factors; Urine

1973
Changes of fluoride content in bone: an index of drug defluorination in vivo.
    Anesthesiology, 1973, Volume: 38, Issue:4

    Topics: Anesthetics; Animals; Biotransformation; Body Weight; Bone and Bones; Chlorine; Drug Interactions; Ethanol; Ethers; Female; Fluoridation; Fluorides; Fluorine; Furans; Halothane; Hydrocarbons, Halogenated; Lethal Dose 50; Male; Methoxyflurane; Methyl Ethers; Mice; Mice, Inbred C57BL; Microsomes, Liver; Phenobarbital; Pregnancy; Proadifen; Rats; Time Factors

1973
Uptake and elimination of methoxyflurane as influenced by enzyme induction in the rat.
    Anesthesiology, 1973, Volume: 38, Issue:4

    Topics: Anesthesia, Inhalation; Animals; Chlorine; Drug Interactions; Enzyme Induction; Fluorides; Kidney; Liver; Male; Methoxyflurane; Microsomes, Liver; Phenobarbital; Proadifen; Radioisotopes; Rats; Time Factors

1973
[Changes in the renal function of dogs during and following methoxyflurane anesthesia].
    Der Anaesthesist, 1973, Volume: 22, Issue:7

    Topics: Anesthesia, Inhalation; Animals; Blood Pressure; Diuresis; Dogs; Fluorides; Glomerular Filtration Rate; Kidney; Kidney Concentrating Ability; Kidney Function Tests; Methoxyflurane; Natriuresis; Urea

1973
Metabolism of methoxyflurane: release of inorganic fluoride in human and rat hepatic microsomes.
    Anesthesiology, 1973, Volume: 39, Issue:6

    Topics: Animals; Biotransformation; Chlorine; Enzyme Induction; Fluorides; Formaldehyde; Humans; Hydrogen-Ion Concentration; Male; Methoxyflurane; Methylcholanthrene; Microsomes, Liver; Nitrous Oxide; Phenobarbital; Rats; Tetracycline

1973
Methoxyflurane anaesthesia for caesarean section and renal function.
    Der Anaesthesist, 1973, Volume: 22, Issue:11

    Topics: Anesthesia, Obstetrical; Cesarean Section; Creatinine; Female; Fluorides; Humans; Kidney; Methoxyflurane; Postoperative Care; Pregnancy; Time Factors; Water-Electrolyte Balance

1973
A comparison of the renal effects and metabolism of enflurane and methoxyflurane in Fischer 344 rats.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 188, Issue:1

    Topics: Anesthetics; Animals; Blood Gas Analysis; Enzyme Induction; Fluorides; Hydrocarbons, Halogenated; Hydrogen-Ion Concentration; Kidney; Kidney Concentrating Ability; Male; Methoxyflurane; Methyl Ethers; Microscopy, Electron; Osmolar Concentration; Phenobarbital; Potassium; Rats; Rats, Inbred Strains; Sodium; Statistics as Topic; Time Factors; Vasopressins

1974
Changes in serum uric acid related to the dose of methoxyflurane.
    British journal of anaesthesia, 1974, Volume: 46, Issue:1

    Topics: Anesthesia, General; Dose-Response Relationship, Drug; Fluorides; Halothane; Humans; Kidney Diseases; Kidney Tubules, Distal; Methoxyflurane; Time Factors; Uric Acid

1974
Maternal and fetal fluorometabolite concentrations after exposure to methoxyflurane.
    American journal of obstetrics and gynecology, 1974, May-15, Volume: 119, Issue:2

    Topics: Adult; Anesthesia, Obstetrical; Episiotomy; Female; Fluorides; Humans; Infant, Newborn; Maternal-Fetal Exchange; Methoxyflurane; Pregnancy; Retrospective Studies; Time Factors; Umbilical Cord

1974
Fluoride concentrations in the human placenta and maternal and cord blood.
    American journal of obstetrics and gynecology, 1974, May-15, Volume: 119, Issue:2

    Topics: Female; Fluorides; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Infant, Newborn; Maternal-Fetal Exchange; Methods; Methoxyflurane; Placenta; Pregnancy; Umbilical Cord

1974
Renal effects and metabolism of isoflurane in man.
    Anesthesiology, 1974, Volume: 40, Issue:6

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthetics; Biotransformation; Dose-Response Relationship, Drug; Ethers; Fluorides; Glomerular Filtration Rate; Halothane; Humans; Hydrocarbons, Fluorinated; Kidney; Male; Methoxyflurane; Middle Aged; Regional Blood Flow; Urine; Vasopressins

1974
Methoxyflurane metabolism and renal function after methoxyflurane analgesia during labor and delivery.
    Anesthesiology, 1974, Volume: 41, Issue:1

    Topics: Analgesia; Anesthesia, Inhalation; Anesthesia, Obstetrical; Creatinine; Female; Fluorides; Humans; Kidney; Kidney Function Tests; Methoxyflurane; Osmolar Concentration

1974
Changes in urine osmolality and urine fluoride concentrations following methoxyflurane anaesthesia.
    British journal of anaesthesia, 1974, Volume: 46, Issue:2

    Topics: Anesthesia, General; Dose-Response Relationship, Drug; Fluorides; Halothane; Humans; Kidney Diseases; Methoxyflurane; Osmolar Concentration; Time Factors; Urine

1974
Effect of methoxyflurane on PAH uptake by rabbit kidney slices.
    The American journal of physiology, 1974, Volume: 227, Issue:2

    Topics: Aminohippuric Acids; Animals; Depression, Chemical; Dose-Response Relationship, Drug; Fluorides; In Vitro Techniques; Kidney; Methoxyflurane; Potassium; Rabbits; Sodium; Water

1974
Effect of inorganic fluoride on the renal concentrating mechanism. Possible nephrotoxicity in man.
    The Journal of laboratory and clinical medicine, 1972, Volume: 79, Issue:2

    Topics: Animals; Body Water; Diuresis; Dogs; Fluorides; Glomerular Filtration Rate; Humans; Kidney; Kidney Concentrating Ability; Mannitol; Methoxyflurane; Natriuresis; Osmolar Concentration; Potassium; Technetium

1972
Renal effects of low-dose methoxyflurane with cardiopulmonary bypass.
    Anesthesiology, 1972, Volume: 36, Issue:3

    Topics: Adjuvants, Anesthesia; Anesthesia, General; Blood Urea Nitrogen; Creatinine; Extracorporeal Circulation; Fluorides; Halothane; Heart Diseases; Humans; Kidney Concentrating Ability; Kidney Diseases; Male; Methoxyflurane; Morphine; Osmolar Concentration; Potassium; Sodium; Uric Acid

1972
Nephrotoxicity from methoxyfluorane.
    British medical journal, 1972, Mar-25, Volume: 1, Issue:5803

    Topics: Animals; Drug Synergism; Fluorides; Humans; Kidney; Kidney Diseases; Methoxyflurane; Rats

1972
Excretion of methoxyflurane metabolites.
    British medical journal, 1972, Jun-03, Volume: 2, Issue:5813

    Topics: Anesthesia, Inhalation; Female; Fluorides; Humans; Kidney; Methoxyflurane; Oxalates; Pregnancy

1972
Dose-related methoxyflurane nephrotoxicity in rats: a biochemical and pathologic correlation.
    Anesthesiology, 1972, Volume: 36, Issue:6

    Topics: Animals; Fluorides; Hydrogen-Ion Concentration; Hypernatremia; Kidney; Kidney Tubules; Male; Methoxyflurane; Microscopy, Electron; Polyuria; Rats; Rats, Inbred Strains; Urea; Vasopressins; Water-Electrolyte Balance

1972
Fluoride and methoxyflurane nephropathy.
    Anesthesiology, 1971, Volume: 35, Issue:3

    Topics: Acute Kidney Injury; Anesthesia, Inhalation; Biotransformation; Fluorides; Humans; Kidney; Methoxyflurane; Oxalates

1971
Methoxyflurane metabolism and renal dysfunction: clinical correlation in man.
    Anesthesiology, 1971, Volume: 35, Issue:3

    Topics: Acute Kidney Injury; Anesthesia, Inhalation; Biotransformation; Fluorides; Humans; Male; Methoxyflurane; Oxalates

1971
Methoxyflurane anesthesia.
    Archives of pathology, 1971, Volume: 92, Issue:6

    Topics: Biotransformation; Fluorides; Humans; Kidney Calculi; Kidney Diseases; Methoxyflurane; Oxalates

1971
Toxicity following methoxyflurane anesthesia. II. Fluoride concentrations in nephrotoxicity.
    JAMA, 1970, Oct-05, Volume: 214, Issue:1

    Topics: Acute Kidney Injury; Anesthesia, General; Cholecystectomy; Electrophoresis; Fluoride Poisoning; Fluorides; Humans; Kidney; Metabolic Clearance Rate; Methoxyflurane; Obesity; Oxalates; Polyuria; Postoperative Complications

1970
Toxicity following methoxyflurane anesthesia. 3. Hemodialysis of metabolites.
    JAMA, 1970, Oct-05, Volume: 214, Issue:1

    Topics: Anesthesia, General; Blood Flow Velocity; Child; Female; Fluorides; Humans; Methoxyflurane; Nephrectomy; Postoperative Complications; Renal Dialysis; Splenectomy

1970
The metabolic degradation of methoxyflurane in man.
    Anesthesiology, 1970, Volume: 33, Issue:6

    Topics: Acetates; Aged; Anesthesia, Inhalation; Carbon Dioxide; Carbon Isotopes; Chlorides; Chromatography, Gas; Female; Fluorides; Humans; Intubation, Intratracheal; Male; Methoxyflurane; Middle Aged; Time Factors

1970
Chronic toxicity of inhalational anaesthetics.
    Annals of the Royal College of Surgeons of England, 1971, Volume: 48, Issue:2

    Topics: Animals; Body Weight; Ethyl Ethers; Fluorides; Fluoroacetates; Guinea Pigs; Halothane; Humans; Liver; Methoxyflurane; Rabbits; Rats

1971
Statement regarding the role of methoxyflurane in the production of renal dysfunction.
    Anesthesiology, 1971, Volume: 34, Issue:6

    Topics: Acute Kidney Injury; Adipose Tissue; Animals; Fluorides; Humans; Kidney Tubules; Methoxyflurane; Muscle Relaxants, Central; Nitrous Oxide; Preanesthetic Medication; Rats; Vasopressins

1971
Chronic exposure to methoxyflurane: a possible occupational hazard to anesthesiologists.
    Anesthesiology, 1971, Volume: 34, Issue:6

    Topics: Air; Anesthesia, Inhalation; Anesthesiology; Chromatography, Gas; Environmental Exposure; Fluorides; Humans; Methoxyflurane; Occupational Diseases; Operating Rooms; Poisoning; Protective Devices; Time Factors

1971
Enflurane, isoflurane, and methoxyflurane metabolism in rat hepatic microsomes from ethanol-treated animals.
    Anesthesiology, 1983, Volume: 58, Issue:3

    Topics: Anesthetics; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Enflurane; Ethanol; Fluorides; Isoflurane; Male; Methoxyflurane; Microsomes, Liver; Rats; Rats, Inbred Strains

1983
Early appearance of methoxyflurane fluorometabolites in mice.
    Pharmacology and therapeutics in dentistry, 1980, Volume: 5, Issue:3-4

    Topics: Animals; Biotransformation; Fluorides; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Methoxyflurane; Mice; Oils; Postural Balance; Zea mays

1980
Deuterated methoxyflurane anesthesia and renal function in Fischer 344 rats.
    Anesthesiology, 1982, Volume: 56, Issue:3

    Topics: Anesthesia; Animals; Deuterium; Enzyme Induction; Fluorides; Kidney; Kidney Diseases; Male; Methoxyflurane; Phenobarbital; Rats; Rats, Inbred F344

1982
Defluorination of methoxyflurane by glutathione and coenzyme B12.
    Research communications in chemical pathology and pharmacology, 1982, Volume: 36, Issue:3

    Topics: Cobamides; Fluorides; Glutathione; Methoxyflurane

1982
Extrahepatic biotransformation of halothane and enflurane.
    Anesthesia and analgesia, 1981, Volume: 60, Issue:3

    Topics: Anaerobiosis; Animals; Benzphetamine; Biotransformation; Chromatography, Gas; Enflurane; Fluorides; Halothane; Kidney; Lung; Male; Methoxyflurane; Microsomes; Microsomes, Liver; Rabbits; Trichloroethylene

1981
Dependence of microsomal methoxyflurane O-demethylation on cytochrome P-450 reductase and the stoichiometry of fluoride ion and formaldehyde release.
    Anesthesia and analgesia, 1982, Volume: 61, Issue:7

    Topics: Animals; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Dealkylation; Fluorides; Formaldehyde; In Vitro Techniques; Male; Methoxyflurane; Microsomes, Liver; Models, Chemical; Rabbits; Rats; Rats, Inbred F344

1982
Serum inorganic fluoride and renal function in dogs after methoxyflurane anesthesia, tetracycline treatment, and surgical manipulation.
    American journal of veterinary research, 1980, Volume: 41, Issue:12

    Topics: Anesthesia, Inhalation; Animals; Blood Urea Nitrogen; Creatinine; Dogs; Fluorides; Kidney; Laparotomy; Methoxyflurane; Tetracycline

1980
Human kidney methoxyflurane and sevoflurane metabolism. Intrarenal fluoride production as a possible mechanism of methoxyflurane nephrotoxicity.
    Anesthesiology, 1995, Volume: 82, Issue:3

    Topics: Cytochrome P-450 Enzyme System; Ethers; Fluorides; Humans; In Vitro Techniques; Isoenzymes; Kidney; Kidney Diseases; Methoxyflurane; Methyl Ethers; Microsomes; Sevoflurane; Substrate Specificity

1995
Identification of cytochrome P450 2E1 as the predominant enzyme catalyzing human liver microsomal defluorination of sevoflurane, isoflurane, and methoxyflurane.
    Anesthesiology, 1993, Volume: 79, Issue:4

    Topics: Anesthetics; Animals; Biotransformation; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Ethers; Fluorides; Fluorine; Humans; Isoflurane; Kinetics; Male; Methoxyflurane; Methyl Ethers; Microsomes, Liver; Oxidoreductases, N-Demethylating; Rats; Sevoflurane

1993
[Inorganic fluoride concentrations and their sequential changes in the five layers of the kidney in rabbits after sevoflurane or methoxyflurane anesthesia].
    Masui. The Japanese journal of anesthesiology, 1999, Volume: 48, Issue:11

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Fluorides; Kidney; Male; Methoxyflurane; Methyl Ethers; Rabbits; Sevoflurane

1999
ANALGESIC PROPERTIES OF SUB-ANAESTHETIC DOSES OF FLUORINATED ANAESTHETICS IN THE MOUSE.
    British journal of pharmacology and chemotherapy, 1965, Volume: 24

    Topics: Analgesics; Analgesics, Non-Narcotic; Anesthesia; Anesthesia, Inhalation; Anesthetics; Animals; Antipyretics; Fluorides; Methoxyflurane; Mice; Nitrous Oxide; Pharmacology; Research; Sulfur; Toxicology

1965
Methoxyflurane revisited: tale of an anesthetic from cradle to grave.
    Anesthesiology, 2006, Volume: 105, Issue:4

    Topics: Anesthesiology; Anesthetics, Inhalation; Animals; Fluorides; History, 20th Century; Humans; Kidney Diseases; Methoxyflurane; Oxalic Acid; Rats

2006
Serum fluoride levels following commencement of methoxyflurane for patient analgesia in an ambulance service.
    British journal of anaesthesia, 2020, Volume: 125, Issue:6

    Topics: Ambulances; Analgesia; Fluorides; Humans; Methoxyflurane

2020