fluorides has been researched along with guanosine triphosphate in 252 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 165 (65.48) | 18.7374 |
| 1990's | 64 (25.40) | 18.2507 |
| 2000's | 19 (7.54) | 29.6817 |
| 2010's | 4 (1.59) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Craven, PA; DeRubertis, FR | 1 |
| Cooper, B; Gregerman, RI; Partilla, JS | 1 |
| Anderson, HJ; Gilman, AG; Haga, T; Ross, EM | 1 |
| Johnson, RA; Welden, J | 1 |
| Atkinson, MM; Herman, WS; Sheppard, JR | 1 |
| Christophe, J; Dehaye, J; Winand, J | 1 |
| Lin, C; Lin, MC; Whitlock, JP | 1 |
| Hamet, P; Johnson, RA; Pilkis, SJ | 1 |
| Hanoune, J; Mavier, P | 1 |
| Finn, FM; Hofmann, K; Montibeller, JA; Ushijima, Y | 1 |
| Londos, C; Rodbell, M | 1 |
| Hosey, MM; Tao, M | 1 |
| Hupka, AL; Sweat, FW; Wincek, TJ | 1 |
| Bennett, V; Cuatrecasas, P; Jacobs, S | 2 |
| Glossmanm, H | 1 |
| Helmreich, EJ; Pfeuffer, T; Zenner, HP | 1 |
| Chlapowski, FJ | 1 |
| Poupon, R | 1 |
| Chayoth, R; Field, JB; Shuman, SJ; Zor, U | 1 |
| Johnson, DG; Thompson, WJ; Williams, RH | 2 |
| Guellaen, G; Hanoune, J; Lacombe, ML; Rene, E | 1 |
| Ahren, K; Koch, Y; Lamprecht, SA; Lindner, HR; Salomon, Y; Zor, U | 1 |
| Burke, G; Friedman, Y; Lang, M | 1 |
| Tomasi, V | 1 |
| Gilman, AG; Ross, EM | 1 |
| Drummond, GI; Snyder, FF | 1 |
| Cassel, D; Pfeuffer, T | 1 |
| Bird, SJ; Maguire, ME | 1 |
| Berman, MF; Lin, MC; Welton, AF | 1 |
| Burgess, WH; Gilman, AG; Howlett, AC; Kretsinger, RH | 1 |
| Anderson, WB; Jaworski, CJ | 1 |
| Ezra, E; Lindner, HR; Salomon, Y | 1 |
| Bourne, HR; Farfel, Z; Johnson, GL; Kaslow, HR | 2 |
| Korenman, SG; Krall, JF | 1 |
| Betuel, H; Cille, Y; Deviller, P | 1 |
| de Jonge, HR | 1 |
| Clement-Cormier, YC; Greengard, P; Kerabian, JW; Parrish, RG; Petzold, GL | 1 |
| Rodbell, M | 3 |
| Bourne, HR; Johnson, GL; Kaslow, HR | 1 |
| Cuatrecasas, P; Hebdon, M; Le Vine, H; Sahyoun, N; Schmitges, CJ | 1 |
| Helmreich, EJ; Levitzki, A | 1 |
| Cheung, WY; Lynch, TJ; Tallant, EA | 1 |
| Cuatrecasas, P; Le Vine, H; Sahyoun, N; Schmitges, CJ | 1 |
| Hickey, AR; Lefkowitz, RJ; Limbird, LE | 1 |
| Johnson, CL; Whitsett, JA | 1 |
| Cassel, D; Eckstein, F; Levkovitz, H; Lowe, M; Selinger, Z | 1 |
| Ayanoglu, G; Mansour, JM; Mansour, TE; Renart, MF | 1 |
| Borghi, C; Giachetti, A; Nicosia, S; Said, SI | 1 |
| Engelhard, VH; Glaser, M; Storm, DR | 1 |
| Dove, JL; Lyman, EM; Sribney, M | 1 |
| Christophe, J; Svoboda, M | 1 |
| Alpert, BE; Schlondorff, D; Yoo, P | 1 |
| Ganguly, U; Greenough, WB | 1 |
| Bennett, V; Cuatrecasas, P | 1 |
| Hanoune, J; Pecker, F | 1 |
| Kather, H; Simon, B | 1 |
| Gregerman, RI; Kalish, MI; Katz, MS; Piñeyro, MA | 1 |
| Ayad, SR; Foster, SJ | 1 |
| Jard, S; Le Bars, NC; Roy, C | 1 |
| Christophe, J; Dehaye, JP; Winand, J | 1 |
| Bhalla, RC; Habhab, O; Halmi, NS | 1 |
| Kimura, N; Nagata, N; Nakane, K | 1 |
| Sweat, FW; Wincek, TJ | 2 |
| Neer, EJ | 1 |
| Franks, DJ | 1 |
| Criss, WE; Pradhan, TK; Wolff, J | 1 |
| Lefkowitz, RJ | 1 |
| Hanoune, J; Lacombe, ML; Pecker, F | 1 |
| Cook, GH; Wolff, J | 2 |
| Buccione, R; Downs, SM; Eppig, JJ | 1 |
| Biondi, C; Buzzi, M; Campi, AL; Cavallaro, R; Ferretti, ME; Pareschi, MC | 1 |
| Johnson, WC; Palczewski, K; Riazance-Lawrence, JH | 1 |
| Cassel, D; Donaldson, JG; Kahn, RA; Klausner, RD | 1 |
| Bitran, J; Hsiao, JK; Manji, HK; Moses, F; Potter, WZ; Risby, ED; Zhou, DF | 1 |
| Hamel, E; Kenney, S; Lin, CM; Skehan, P | 1 |
| Anderson, FL; Bristow, MR; Feldman, AM; Hershberger, RE; Kimball, JA; Wynn, JR | 1 |
| Comerford, JG; Dawson, AP | 1 |
| Bourne, HR; Jones, DT; Masters, SB; Reed, RR | 1 |
| Cahalan, MD; McCloskey, MA | 1 |
| Andersson, T; Bengtsson, T; Särndahl, E; Stendahl, O | 1 |
| Fennell, DF; Kurrus, JA; McIntyre, TM; Prescott, SM; Whatley, RE; Zimmerman, GA | 1 |
| Teitelbaum, I | 1 |
| de Laat, SW; Lambrechts, AC; Moolenaar, WH; Remorie, R; Tertoolen, LG; Tilly, BC | 1 |
| LaBelle, EF; Murray, BM | 1 |
| Gutierrez, GE; Katz, MS; Mundy, GR | 1 |
| Csongor, J; Fóris, G; Fülöp, T; Leövey, A; Varga, Z | 1 |
| Kirkwood, A; Lisman, JE; Weiner, D | 1 |
| Boyer, JL; Downes, CP; Evans, T; Harden, TK; Northup, JK; Waldo, GL | 1 |
| Ozawa, H; Rasenick, MM | 1 |
| Balch, WE; Beckers, CJ | 1 |
| Kondo, K; Kozawa, O; Oiso, Y; Takatsuki, K | 1 |
| Boulias, C; Moscarello, MA | 1 |
| Cockcroft, S; Geny, B; Stutchfield, J | 1 |
| Aussel, C; Dallanegra, A; Fehlmann, M; Pelassy, C | 1 |
| Fein, A; Szuts, EZ; Wood, SF | 1 |
| Carlier, MF; Didry, D; Pantaloni, D; Simon, C | 1 |
| Gleason, ML; Glick, BS; Malhotra, V; Melançon, P; Orci, L; Rothman, JE; Serafini, T; Weidman, PJ | 1 |
| Bigay, J; Chabre, M; Deterre, P; Pfister, C | 2 |
| Aussel, C; Fehlmann, M; Ferrua, B; Mary, D; Pelassy, C; Peyron, JF | 1 |
| Casteels, R; De Smedt, H; Missiaen, L; Vrolix, M; Wuytack, F | 1 |
| Ramkumar, V; Stiles, GL | 1 |
| Fluharty, SJ; Granneman, JG; MacKenzie, RG; Stricker, EM; Zigmond, MJ | 1 |
| Boland, SR; Katz, MS; Schmidt, SJ | 1 |
| Bollack, C; Helwig, JJ; Judes, C; Mandel, P | 1 |
| Lees, M; Smith, G; Turnberg, L; Warhurst, G | 1 |
| Bilezikian, JP; Feigin, AS; Owens, JM; Shane, E; Yeh, M | 1 |
| Birnbaumer, L; Caron, MG; Cerione, RA; Codina, J; Hildebrandt, JD; Iyengar, R; Lefkowitz, RJ; Mattera, R; Rojas, FJ; Sunyer, T | 1 |
| Manning, DR; Nakada, MT; Woolkalis, MJ | 1 |
| Brandt, DR; Ross, EM | 1 |
| Akard, LP; English, D; Gabig, TG; Schell, MJ | 1 |
| Hasegawa-Sasaki, H; Lutz, F; Sasaki, T | 1 |
| Greiner, C; Jakobs, KH | 1 |
| Sternweis, PC | 1 |
| Humphreys, WG; Macdonald, TL | 1 |
| Beiderman, B; Bourne, HR; Masters, SB; Miller, RT; Sullivan, KA | 1 |
| Luduena, RF; Manso-Martínez, R; Palomares, R; Prasad, V | 1 |
| Ageeva, OG; Chesnokova, LS; Ivashkin, VT; Konicheva, TL; Vasil'ev, VIu | 1 |
| Gierschik, P; Spiegel, AM | 1 |
| Dudai, Y; Zvi, S | 1 |
| Moore, WV; Wolff, J | 1 |
| Gorbach, SL; Kantor, HS; Tao, P | 1 |
| Howell, SL; Montague, W | 1 |
| Franks, DJ; Stansfield, DA | 1 |
| Harwood, JP; Krishna, G | 1 |
| Birnbaumer, L | 1 |
| Aurbach, GD; Spiegel, AM | 1 |
| Jarett, L; Rahmanian, M | 1 |
| Bockaert, J; Jard, S; Roy, C | 1 |
| Deery, DJ; Howell, SL | 1 |
| Harwood, JP; Lin, MC; Londos, C; Rodbell, M; Salomon, Y; Schramm, M; Wolff, J | 1 |
| Goldstein, ES; Snyder, LA | 1 |
| Culp, W; Hardesty, B; Irvin, J; Obrig, T | 1 |
| Aurbach, GD; Bilezikian, JP | 1 |
| Birnbaumer, L; Pohl, SL; Rodbell, M; Sundby, F | 1 |
| Laszlo, AH; Scotto, JM; Soifer, D | 1 |
| Dumont, JE; Matsuzaki, S | 1 |
| Chambaut, AM; Hanoune, J; Leray, F | 1 |
| Cogniaux, J | 1 |
| Rosen, MR; Triner, L; Verosky, M; Vulliemoz, Y | 1 |
| Barr, RE; LeGrand, RD; Walkenbach, RJ | 1 |
| Essenberg, RC; Sauer, JR; Schmidt, SP | 1 |
| Birnbaumer, L; Codina, J; Hildebrandt, J; Iyengar, R; Manclark, CR; Sekura, RD; Sunyer, T | 1 |
| Cros, GH; Katz, S; McNeill, JH | 1 |
| Koschel, K | 1 |
| Larriba, G; Leal, F; Ruiz-Herrera, J; Villanueva, JR | 1 |
| Ezra, E; Salomon, Y | 1 |
| Aurbach, GD; Downs, RW; Reen, S; Singer, M; Spiegel, AM | 1 |
| Lad, PM; Nielsen, TB; Preston, MS; Rodbell, M | 1 |
| Bhat, MK; Birnbaumer, L; Iyengar, R; Riser, ME | 1 |
| Ambesi-Impiombato, FS; De Wolf, MJ; Kohn, LD; Vitti, P | 1 |
| Aurbach, GD | 1 |
| Goldhammer, A; Wolff, J | 1 |
| Aurbach, GD; Downs, RW; Krawietz, W; Spiegel, AM | 1 |
| Daveloose, D; Garnier, J; Salesse, R | 1 |
| Gilman, AG; Northup, JK; Smigel, MD | 1 |
| Maguire, ME | 1 |
| Agli, B; Giudicelli, Y; Lacasa, D | 1 |
| Gilman, AG; Northup, JK; Smigel, MD; Sternweis, PC | 1 |
| Corson, DW; Fein, A; Walthall, WW | 1 |
| Attramadal, H; Hansson, V; Jahnsen, T; Le Gac, F | 1 |
| Bokoch, GM; Gilman, AG; Katada, T; Northup, JK; Smigel, M; Ui, M | 1 |
| Burke, G; Crowell, D; Friedman, Y; Wilger, J | 1 |
| Corson, DW; Fein, A | 1 |
| Johnson, RA | 1 |
| Gilman, AG; Northup, JK; Ross, EM; Schleifer, LS; Smigel, MD; Sternweis, PC | 1 |
| Drummond, GI; Nambi, P | 1 |
| Avdonin, PV; Panchenko, MP; Tkachuk, VA | 1 |
| Cantau, B; Guillon, G; Jard, S | 1 |
| Aurbach, GD; Downs, RW; Krawietz, W; Levine, MA; Marx, SJ; Reen, SA; Singer, MJ; Spiegel, AM; Woodard, CJ | 1 |
| Birnbaumer, L; Iyengar, R | 1 |
| Fishman, PH; Hagmann, J | 1 |
| Cook, GH; Goldhammer, A; Wolff, J | 1 |
| Lydon, NB; Stansfield, DA; Young, JL | 1 |
| Kaznacheyeva, EV; Kiselyov, KI; Kuryshev, YA; Mamin, AG; Mozhayeva, GN; Naumov, AP | 1 |
| Biondi, C; Buzzi, M; Cavallaro, R; Fabbri, E; Ferretti, ME; Vesce, G | 1 |
| Fujishiro, N; Imanaga, I; Inoue, M | 1 |
| Fujita, A; Hata, F; Nakajima, H; Nishio, H; Takeuchi, T | 1 |
| Kehoe, J | 1 |
| Gilman, AG; Kleuss, C; Lee, E; Raw, AS; Sprang, SR | 1 |
| Lau, C; Seidler, FJ; Slotkin, TA | 1 |
| Berghuis, AM; Coleman, DE; Gilman, AG; Lee, E; Linder, ME; Sprang, SR | 1 |
| De Boer, AH; Korthout, HA; Prins, HB; Van der Hoeven, PC; Van der Molen, GW | 1 |
| Inanobe, A; Katada, T; Kurachi, Y; Terzic, A; Tung, RT | 1 |
| Cassel, D; Donaldson, JG; Finazzi, D; Klausner, RD | 1 |
| McCook, EC; Seidler, FJ; Slotkin, TA | 1 |
| Chabre, M; Chardin, P; Faurobert, E; Otto-Bruc, A | 1 |
| Jope, RS; Powers, R; Song, L | 1 |
| Fasolato, C; Hoth, M; Penner, R | 1 |
| Carter, LL; Redelmeier, TE; Schmid, SL; Woollenweber, LA | 1 |
| Augustine, GJ; Doroshenko, PA; Hess, SD | 1 |
| Carlier, MF; Melki, R | 1 |
| Hall, JL; Hamilton, CD; Roth, DA; Stanley, WC; White, CD | 1 |
| Parekh, AB | 1 |
| Matzel, LD; Rogers, RF; Talk, AC | 1 |
| Berman, DM; Gilman, AG; Kozasa, T | 1 |
| Maeda, S; Miwa, Y; Saeki, M; Saito, K; Yamaji, A | 1 |
| Iwasa, T; Kikkawa, S; Nakagawa, M; Tominaga, K; Tsuda, M | 1 |
| Giannuzzi, CE; Seidler, FJ; Slotkin, TA | 1 |
| Berman, DM; Gilman, AG; Sprang, SR; Tesmer, JJ | 1 |
| Ichida, S; Imoto, K; Tahara, M; Wada, T; Zhang, YA | 1 |
| Ahmadian, MR; Kabsch, W; Lautwein, A; Scheffzek, K; Schmitz, F; Wiesmüller, L; Wittinghofer, A | 1 |
| Artemyev, NO; Lipkin, VM; Natochin, M | 1 |
| Díaz, JF; Engelborghs, Y; Sillen, A | 1 |
| Andersson, T; Dimitrijevic, I; Eckerdal, J; Zheng, L | 1 |
| Boyett, MR; Shui, Z; Zang, WJ | 1 |
| Cerione, RA; Hoffman, GR; Nassar, N; Oswald, RE | 1 |
| Barritt, GJ; Fernando, KC; Gregory, RB | 1 |
| Sprang, SR | 1 |
| Cortese, JD | 1 |
| Berlot, CH; Grishina, G | 1 |
| Brügger, B; Eberle, H; Gerdes, HH; Gkantiragas, I; Helms, JB; Helms-Brons, D; Nickel, W; Nürnberg, B; Wieland, FT | 1 |
| Bollag, G; Gilman, AG; Hart, MJ; Jiang, X; Kozasa, T; Singer, WD; Sternweis, PC; Sternweis, PM | 1 |
| Bollag, G; Gilman, AG; Hart, MJ; Jiang, X; Kozasa, T; Roscoe, W; Singer, WD; Sternweis, PC | 1 |
| McCook, EC; Seidler, FJ; Slotkin, TA; Zhang, J | 1 |
| Artemyev, NO; Granovsky, AE; Natochin, M | 1 |
| Zhang, B; Zheng, Y | 1 |
| Brown, EJ; Chung, J; Dimitry, J; Frazier, WA; Gao, AG; Lindberg, FP; Linder, ME | 1 |
| Arthur, JM; Collinsworth, GP; Gettys, TW; Raymond, JR | 1 |
| Geyer, M; Herrmann, C; Praefcke, GJ; Robert Kalbitzer, H; Schwemmle, M | 1 |
| Coleman, DE; Sprang, SR | 1 |
| Ryle, MJ; Seefeldt, LC | 1 |
| Clabecq, A; Darchen, F; Henry, JP | 1 |
| Li, H; Wu, G; Yang, Z | 1 |
| Quinton, PM; Reddy, MM; Sun, D | 1 |
| Cismowski, MJ; Draper, E; Metodiev, M; Stone, DE | 1 |
| Lomax, TL; Perdue, DO | 1 |
| Miller, HP; Panda, D; Wilson, L | 1 |
| Aebi, U; Haener, M; Haller, O; Kochs, G | 1 |
| Brito, M; Guzmán, L; Hinrichs, MV; Olate, J; Romo, X; Soto, X | 1 |
| Chakrabarti, PP; Daumke, O; Vetter, IR; Weyand, M; Wittinghofer, A | 1 |
| Eto, M; Luo, S; Matthew, JD; Somlyo, AP; Somlyo, AV; Stevenson, AS | 1 |
| González, JM; Mingorance, J; Rivas, G; Tadros, M; Vélez, M; Vicente, M | 1 |
| Cresswell, P; Lu, YE; Modiano, N | 1 |
| Cerione, RA; Pereira, R | 1 |
| Jehl, M; Nayak, SK; Ross, EM; Tang, W; Tu, Y; Woodson, J | 1 |
| Coon, JS; Focia, PJ; Freymann, DM; Gawronski-Salerno, J | 1 |
| Eathiraj, S; Lambright, DG; Munson, M; Pan, X | 1 |
| Benharouga, M; Biard, J; De Keukeleire, B; Micoud, J | 1 |
| Frank, J; Gursky, R; Kjeldgaard, M; Nilsson, J; Nissen, P; Sengupta, J | 1 |
| Gasper, R; Gotthardt, K; Meyer, S; Sirajuddin, M; Wittinghofer, A | 1 |
| Ash, MR; Guss, JM; Jormakka, M; Maher, MJ | 1 |
| Benvin, NM; Byrnes, LJ; O'Donnell, JP; Singh, A; Sondermann, H; Szeto, K; Zipfel, WR | 1 |
| Ermolenko, DN; Farah, E; Salsi, E | 1 |
| Feng, W; Kong, R; Lou, J; Ren, J; Wu, JY; Yi, F; Zhu, L | 1 |
9 review(s) available for fluorides and guanosine triphosphate
| Article | Year |
|---|---|
Hormone-receptor--adenylate cyclase interactions.
Topics: Adenylyl Cyclases; Animals; Cholera Toxin; Enzyme Activation; Fluorides; Guanosine Triphosphate; Kinetics; Membrane Fluidity; Receptors, Cyclic AMP | 1979 |
Regulation of hormone receptors and adenylyl cyclases by guanine nucleotide binding N proteins.
Topics: Adenylyl Cyclases; Animals; Colforsin; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Triphosphate; Hormones; Humans; Hydrolysis; Kinetics; Magnesium; Molecular Weight; Nucleotides; Protein Conformation; Rats; Receptors, Cell Surface | 1985 |
Hormone-sensitive adenylyl cyclases. Useful models for studying hormone receptor functions in cell-free systems.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Calcium; Cations, Divalent; Cell Membrane; Cell-Free System; Epinephrine; Fluorides; Glucagon; Guanosine Triphosphate; Kidney Medulla; Kinetics; Liver; Luteinizing Hormone; Models, Biological; Propranolol; Prostaglandins; Receptors, Cell Surface; Secretin; Thyrotropin; Vasopressins | 1973 |
Mechanisms in the vectorial receptor-adenylate cyclase signal transduction.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cell Line; Fluorides; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Lymphoma; Magnesium; Mice; Models, Biological; Molecular Weight; Receptors, Cell Surface | 1984 |
Genetic analysis of hormone-sensitive adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cholera Toxin; Cyclic AMP; Fluorides; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hormones; Humans; Magnesium; Mice; Models, Biological; Receptors, Adrenergic, beta | 1980 |
Polypeptide and amine hormone regulation of adenylate cyclase.
Topics: Adenosine Diphosphate; Adenylyl Cyclases; Animals; Cholera Toxin; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Receptors, Adrenergic, beta; Receptors, Cell Surface; Receptors, Glucagon; Receptors, Parathyroid Hormone | 1982 |
Mechanisms of guanine nucleotide-mediated regulation of adenylate cyclase activity.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Bacterial Toxins; Cell Membrane; Cyclic AMP; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hormones; Humans; Kinetics; Mice; Rabbits; Rats; Receptors, Cell Surface; Thionucleotides; Virulence Factors, Bordetella | 1984 |
Nobel Lecture. Signal transduction: evolution of an idea.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Cross-Linking Reagents; Detergents; Fluorides; Glucagon; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Liver; Models, Biological; Nobel Prize; Receptors, Cell Surface; Second Messenger Systems; Signal Transduction | 1995 |
It takes two to tango: regulation of G proteins by dimerization.
Topics: Aluminum Compounds; Animals; Binding Sites; Dimerization; Fluorides; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Models, Molecular; Plant Proteins; Protein Structure, Quaternary | 2009 |
243 other study(ies) available for fluorides and guanosine triphosphate
| Article | Year |
|---|---|
Properties of the guanylate cyclase-guanosine 3':5'-monophosphate system of rat renal cortex. Activation of guanylate cyclase and calcium-independent modulation of tissue guanosine 3':5'-monophosphate by sodium azide.
Topics: Animals; Azides; Calcium; Carbachol; Cyclic GMP; Enzyme Activation; Fluorides; Guanosine Triphosphate; Guanylate Cyclase; Kidney Cortex; Kinetics; Magnesium; Male; Manganese; Rats; Tetracaine | 1976 |
Human fat cell adenylate cyclase. Enzyme characterization and guanine nucleotide effects on epinephrine responsiveness in cell membranes.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Adult; Cell Membrane; Epinephrine; Female; Fluorides; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Humans; Hydrogen-Ion Concentration; Magnesium; Male; Temperature | 1976 |
Adenylate cyclase permanently uncoupled from hormone receptors in a novel variant of S49 mouse lymphoma cells.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Bacterial Toxins; Binding, Competitive; Cell Line; Cyclic AMP; Fluorides; Guanosine Triphosphate; Isoproterenol; Karyotyping; Lymphoma; Mice; Mutation; Prostaglandins E; Receptors, Adrenergic; Receptors, Adrenergic, beta; Vibrio cholerae | 1977 |
Characteristics of the enzymatic hydrolysis of 5'-adenylylimidodiphosphate: implications for the study of adenylate cyclase.
Topics: Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Adenylyl Cyclases; Adenylyl Imidodiphosphate; Animals; Cations, Divalent; Cell Membrane; Dithiothreitol; Edetic Acid; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hydrogen-Ion Concentration; Kinetics; Liver; Rats; Temperature; Uridine Diphosphate Glucose | 1977 |
An octopamine-sensitive adenylate cyclase in the central nervous system of Limulus polyphemus.
Topics: Adenylyl Cyclases; Animals; Central Nervous System; Enzyme Activation; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Horseshoe Crabs; Kinetics; Octopamine | 1977 |
Proceedings: Regulation of adenylate cyclase activity in the 25000 X g sediment of adipose tissue from obese-hyperglycemic (ob/ob) mice from Bar Harbor.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Drug Synergism; Ethanol; Fluorides; Guanine Nucleotides; Guanosine Triphosphate; Isoproterenol; Male; Mice; Mice, Obese; Prostaglandins E | 1976 |
Reduction of GTP activation of adenylate cyclase system by its coupling to hormone receptor.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Butyrates; Cell Membrane; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; HeLa Cells; Humans; Isoproterenol; Kinetics; Receptors, Cyclic AMP | 1979 |
Liver membrane adenylate cyclase. Synergistic effects of anions on fluoride, glucagon, and guanyl nucleotide stimulation.
Topics: Adenosine Triphosphatases; Adenylyl Cyclases; Animals; Anions; Azides; Cell Membrane; Cyanides; Enzyme Activation; Fluorides; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Kinetics; Liver; Rats | 1975 |
Adenylate cyclase from rat-liver plasma membrane: inhibition by mersalyl and other mercurial derivatives.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Animals; Cell Membrane; Chloromercuribenzoates; Dose-Response Relationship, Drug; Enzyme Activation; Female; Fluorides; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Magnesium; Mercaptoethanol; Mercury; Mersalyl; Organomercury Compounds; Organometallic Compounds; Rats | 1975 |
Adenylate cyclase system of bovine adrenal plasma membranes.
Topics: Adenosine Triphosphatases; Adenylyl Cyclases; Adrenal Cortex; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Calcium; Cattle; Cell Membrane; Chelating Agents; Fluorides; Guanosine Triphosphate; Kinetics; Ouabain; Temperature; Theophylline | 1975 |
Multiple inhibitory and activating effects of nucleotides and magnesium on adrenal adenylate cyclase.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Fluorides; Guanine Nucleotides; Guanosine Triphosphate; Kinetics; Magnesium; Male; Purine Nucleotides; Pyrimidine Nucleotides; Rats | 1975 |
Effect of 5'guanylylimidodiphosphate on prostaglandin- and fluoride- sensitive adenylate cyclase of rabbit red blood cells.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Dose-Response Relationship, Drug; Enzyme Activation; Erythrocytes; Fluorides; Guanine Nucleotides; Guanosine Triphosphate; Imides; Kinetics; Phosphoric Diester Hydrolases; Prostaglandins E; Rabbits; Time Factors | 1975 |
Stimulation of adenylate cyclase from isolated hepatocytes and Kupffer cells.
Topics: Adenylyl Cyclases; Animals; Calcium; Fluorides; Glucagon; Guanosine Triphosphate; Hyaluronoglucosaminidase; In Vitro Techniques; Iron; Isoproterenol; Kupffer Cells; Liver; Male; Microbial Collagenase; Microscopy, Phase-Contrast; Peptides; Perfusion; Prostaglandins E; Rats; Secretin | 1975 |
Irreversible stimulation of adenylate cyclase activity of fat cell membranes of phosphoramidate and phosphonate analogs of GTP.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Aniline Compounds; Animals; Binding, Competitive; Cell Membrane; Diphosphates; Dithiothreitol; Edetic Acid; Fluorides; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Hydroxylamines; Isoproterenol; Mercury; Organometallic Compounds; Phosphates; Rats; Sodium | 1975 |
Adrenal cortex adenylate cyclase: solubilization of adenylate cyclase and guanyl nucleotide binding sites.
Topics: Adenylyl Cyclases; Adrenal Cortex; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Binding Sites; Cattle; Cell Membrane; Enzyme Activation; Fluorides; Guanosine Triphosphate; Polyethylene Glycols; Receptors, Cell Surface; Solubility; Stimulation, Chemical | 1975 |
Signal transfer from hormone receptor to adenylate cyclase.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Binding Sites; Calcium; Catecholamines; Cell Membrane; Enzyme Activation; Fluorides; Glucagon; Guanosine Triphosphate; Insulin; Kinetics; Lipids; Liver; Magnesium; Membranes; Myocardium; Protein Binding; Rabbits; Rats; Receptors, Cell Surface | 1976 |
Adenylate cyclase and phosphodiesterase in transitional epithelium of the urinary bladder.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Cell Fractionation; Cell-Free System; Cytosol; Drug Interactions; Epinephrine; Epithelium; Fluorides; Guanosine Triphosphate; Kinetics; Male; Membranes; Phosphoric Diester Hydrolases; Prostaglandins E; Rabbits; Stimulation, Chemical; Urinary Bladder | 1976 |
Activity of human adenylate cyclase from human fat cell membranes.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Adult; Aged; Animals; Cell Membrane; Cyclic AMP; Cytosine Nucleotides; Enzyme Activation; Epinephrine; Fluorides; Glucagon; Guanosine Triphosphate; Humans; Middle Aged; Rats | 1975 |
Exposure of thyroid slices to thyroid-stimulating hormone induces refractoriness of the cyclic AMP system to subsequent hormone stimulation.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cattle; Cyclic AMP; Dogs; Fluorides; Guanosine Triphosphate; Humans; In Vitro Techniques; Kinetics; Prostaglandins E; Puromycin; Sheep; Species Specificity; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 1976 |
Hormonal regulation of pancreatic islet adenyl cyclase.
Topics: Adenylyl Cyclases; Adrenocorticotropic Hormone; Animals; Cell Membrane; Cholecystokinin; Fluorides; Glucagon; Growth Hormone; Guanosine Triphosphate; Insulin; Islets of Langerhans; Isoproterenol; Kinetics; Male; Phentolamine; Propranolol; Prostaglandins E; Rats; Secretin | 1976 |
Transformation of the beta2 adrenoceptor in normal rat liver into a beta1 type in Zajdela hepatoma.
Topics: Adenylyl Cyclases; Animals; Carcinoma, Hepatocellular; Catecholamines; Enzyme Activation; Epinephrine; Female; Fluorides; Glucagon; Guanosine Triphosphate; Liver; Liver Neoplasms; Neoplasms, Experimental; Rats; Receptors, Adrenergic | 1976 |
Mechanism of hormonally induced refractoriness of ovarian adenylate cyclase to luteinizing hormone and prostaglandin E.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Binding Sites; Chorionic Gonadotropin; Cyclic AMP; Cycloheximide; Dactinomycin; Female; Fluorides; Guanine Nucleotides; Guanosine Triphosphate; Luteinizing Hormone; Ovarian Follicle; Prostaglandins E; Protein Binding; Rats | 1977 |
Inhibition of thyroid adenylate cyclase by thyroid hormone: a possible locus for the "short-loop" negative feedback phenomenon.
Topics: Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Animals; Bucladesine; Cattle; Cell Membrane; Feedback; Fluorides; Guanosine Triphosphate; Inosine Nucleotides; Mice; Ornithine Decarboxylase; Prostaglandins E; Prostaglandins F; Rats; Thyroid Gland; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine | 1977 |
Prostaglandin E1 as an intercellular regulator of cyclic AMP levels.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cyclic AMP; Epinephrine; Fluorides; Glucagon; Guanosine Triphosphate; Inflammation; Liver; Lymphocytes; Phospholipases; Prostaglandins E; Rats; Receptors, Cell Surface; Receptors, Prostaglandin; Trypsin | 1976 |
Reconstitution of catecholamine-sensitive adenylate cyclase activity: interactions of solubilized components with receptor-replete membranes.
Topics: Adenylyl Cyclases; Binding, Competitive; Catecholamines; Cell Membrane; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; L Cells; Mutation; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1977 |
Activation and stabilization of cardiac adenylate cyclase by GTP analog and fluoride.
Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hot Temperature; In Vitro Techniques; Kinetics; Magnesium; Myocardium; Rabbits | 1978 |
Mechanism of cholera toxin action: covalent modification of the guanyl nucleotide-binding protein of the adenylate cyclase system.
Topics: Adenosine Diphosphate Sugars; Adenylyl Cyclases; Allosteric Site; Animals; Carrier Proteins; Cholera Toxin; Columbidae; Enzyme Activation; Erythrocyte Membrane; Fluorides; Guanosine Triphosphate; Humans; NAD; Ribose | 1978 |
The agonist-specific effect of magnesium ion on binding by beta-adrenergic receptors in S49 lymphoma cells. Interaction of GTP and magnesium in adenylate cyclase activation.
Topics: Adenylyl Cyclases; Cell Line; Cell Membrane; Enzyme Activation; Fluorides; Guanosine Triphosphate; Isoproterenol; Kinetics; Lymphoma; Magnesium; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1978 |
Essential role of GTP in the expression of adenylate cyclase activity after cholera toxin treatment.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Enzyme Activation; Fluorides; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Liver; NAD; Peptide Fragments; Rats | 1978 |
S49 lymphoma wild type and variant clones contain normal calcium dependent regulator.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Calcium; Calmodulin; Carrier Proteins; Cell Line; Clone Cells; Enzyme Activation; Fluorides; Guanosine Triphosphate; Isoproterenol; Lymphoma; Neoplasms, Experimental | 1978 |
Isoproterenol-induced desensitization of adenylate cyclase responsiveness in a cell-free system.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Cyclic AMP; Fluorides; Guanosine Triphosphate; Isoproterenol; Kidney; Kinetics; Prostaglandins E; Rats | 1979 |
Lutropin induced desensitization of rat ovarian adenylate cyclase: a GTP-dependent process.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Female; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Luteinizing Hormone; Ovary; Rats; Receptors, Cell Surface | 1979 |
Adenylate cyclase assembled in vitro: cholera toxin substrates determine different patterns of regulation by isoproterenol and guanosine 5'-triphosphate.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Erythrocyte Membrane; Fluorides; Guanine Nucleotides; Guanosine Triphosphate; Humans; In Vitro Techniques; Isoproterenol; Kinetics; Lymphoma; Mice; Neoplasms, Experimental; Receptors, Adrenergic, beta; Turkeys | 1979 |
Regulation of uterine smooth muscle cell beta-adrenergic catecholamine-sensitive adenylate cyclase by Mg2+ and guanylyl nucleotide.
Topics: Adenylyl Cyclases; Animals; Enzyme Activation; Female; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Magnesium; Male; Muscle, Smooth; Myometrium; Rats; Receptors, Adrenergic, beta; Uterus | 1979 |
Guanyl cyclase activity of human blood lymphocytes.
Topics: Cations, Divalent; Chromatography, Thin Layer; Concanavalin A; Fluorides; Guanosine Triphosphate; Guanylate Cyclase; Humans; Kinetics; Lectins; Lymphocytes; Manganese; Phosphoenolpyruvate; Ribonucleotides; Subcellular Fractions; Time Factors | 1975 |
Properties of guanylate cyclase and levels of cyclic GMP in rat small intestinal villous and crypt cells.
Topics: Adenine Nucleotides; Alloxan; Amino Acids; Animals; Anti-Bacterial Agents; Carboxylic Acids; Cyclic GMP; Epinephrine; Fluorides; Glucose; Guanosine Triphosphate; Guanylate Cyclase; Intestinal Mucosa; Intestine, Small; Kinetics; Manganese; Oxaloacetates; Phosphoenolpyruvate; Polyethylene Glycols; Prostaglandins; Rats; Theophylline | 1975 |
Characterization of a dopamine-sensitive adenylate cyclase in the rat caudate nucleus.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cations, Divalent; Caudate Nucleus; Cell Nucleus; Cyclic AMP; Cytosol; Dopamine; Egtazic Acid; Fluorides; Fluphenazine; Guanosine Triphosphate; Hydrogen-Ion Concentration; Magnesium; Male; Manganese; Microsomes; Mitochondria; Myelin Sheath; Nerve Endings; Phosphorus Radioisotopes; Rats; Temperature | 1975 |
On the mechanism of activation of fat cell adenylate cyclase by guanine nucleotides. An explanation for the biphasic inhibitory and stimulatory effects of the nucleotides and the role of hormones.
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Cell Membrane; Enzyme Activation; Epinephrine; Fluorides; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Hydrogen-Ion Concentration; Kinetics; Magnesium; Rats; Time Factors | 1975 |
Reconstitution of cholera toxin-activated adenylate cyclase.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Binding Sites; Cell Line; Cholera Toxin; Enzyme Activation; Ethylmaleimide; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Macromolecular Substances; Mutation | 1978 |
Properties of the interaction of fluoride- and guanylyl-5'-imidodiphosphate-regulatory proteins with adenylate cyclase.
Topics: Adenylyl Cyclases; Enzyme Activation; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Magnesium; Membrane Proteins; Sodium Fluoride | 1978 |
Rat brain adenylate cyclase. Further studies on its stimulation by a Ca2+-binding protein.
Topics: Adenylyl Cyclases; Animals; Brain; Calcium; Carrier Proteins; Egtazic Acid; Enzyme Activation; Fluorides; Guanine Nucleotides; Guanosine Triphosphate; Kinetics; Rats | 1977 |
Molecular resolution and reconstitution of the GPP (NH) P and NAF sensitive adenylate cyclase system.
Topics: Adenylyl Cyclases; Animals; Brain; Edetic Acid; Enzyme Activation; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Magnesium; Male; Rats | 1977 |
Unique uncoupling of the frog erythrocyte adenylate cyclase system by manganese. Loss of hormone and guanine nucleotide-sensitive enzyme activities without loss of nucleotide-sensitive, high affinity agonist binding.
Topics: Adenylyl Cyclases; Animals; Anura; Erythrocyte Membrane; Erythrocytes; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Magnesium; Manganese; Prostaglandins E | 1979 |
Adenylate cyclase from human decidua parietalis.
Topics: Adenylyl Cyclases; Amnion; Chorion; Decidua; Dose-Response Relationship, Drug; Epinephrine; Ethanol; Female; Fluorides; Guanosine Triphosphate; Humans; In Vitro Techniques; Pregnancy; Prostaglandins | 1979 |
Guanosine 5'-O-(2-thiodiphosphate). An inhibitor of adenylate cyclase stimulation by guanine nucleotides and fluoride ions.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Erythrocyte Membrane; Fluorides; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Liver; Parotid Gland; Propranolol; Rats; Thionucleotides; Turkeys | 1979 |
Fluoride and guanosine nucleotide activated adenylate cyclase from Fasciola hepatica: reconstitution after inactivation.
Topics: Adenylyl Cyclases; Animals; Enzyme Activation; Ethylmaleimide; Fasciola hepatica; Fluorides; Guanosine Triphosphate; Kinetics; Thionucleotides | 1979 |
Adenylate cyclase of rat pituitary gland: stimulation by vasoactive intestinal polypeptide (VIP).
Topics: Adenylyl Cyclases; Animals; Enzyme Activation; Fluorides; Gastrointestinal Hormones; Guanosine Triphosphate; Kinetics; Male; Norepinephrine; Pituitary Gland; Prostaglandins E; Rats; Vasoactive Intestinal Peptide | 1979 |
Negative cooperativity exhibited by prostaglandin E1 stimulated adenylate cyclase in LM cells.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Dose-Response Relationship, Drug; Fluorides; Guanosine Triphosphate; Kinetics; Magnesium; Mice; Prostaglandins E | 1978 |
Studies on the synthesis of CDP-diacylglycerol: stimulation by GTP and inhibition by ATP and fluoride.
Topics: Adenosine Triphosphate; Animals; Cytidine Diphosphate Diglycerides; Enzyme Activation; Fluorides; Guanosine Triphosphate; Kinetics; Microsomes, Liver; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Phospholipids; Rats; Ribonucleotides | 1977 |
The monovalent anions chloride and azide as potent activators of NaF- and p(NH)ppG-stimulation of pancreatic adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Azides; Cell Membrane; Dose-Response Relationship, Drug; Enzyme Activation; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Pancreas; Rats; Sodium Chloride; Sodium Fluoride | 1978 |
Stimulation of adenylate cyclase in isolated rat glomeruli by prostaglandins.
Topics: Adenylyl Cyclases; Alkaline Phosphatase; Animals; Dose-Response Relationship, Drug; Enzyme Activation; Fluorides; Guanosine Triphosphate; Kidney Glomerulus; Kidney Tubules; Male; Parathyroid Hormone; Prostaglandins; Prostaglandins E; Rats | 1978 |
Effect of fluoride & 5' guanylyl imidodiphosphate on cholera toxin-treated cell.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Cholera Toxin; Epinephrine; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Male; Rats | 1978 |
Mechanism of action of Vibrio cholerae enterotoxin. Effects on adenylate cyclase of toad and rat erythrocyte plasma membranes.
Topics: Adenylyl Cyclases; Animals; Bufo marinus; Cell Membrane; Enterotoxins; Enzyme Activation; Epinephrine; Erythrocytes; Fluorides; Guanosine Triphosphate; Humans; Isoproterenol; Kinetics; Magnesium; Protein Binding; Rats; Vibrio cholerae | 1975 |
Activation of epinephrine-sensitive adenylate cyclase in rat liver by cytosolic protein-nucleotide complex.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cytosol; Enzyme Activation; Epinephrine; Female; Fluorides; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Proteins; Rats | 1977 |
Epinephrine-sensitive adenylate cyclase of human fat cell ghosts: stablilzation of enzyme activity by fluoride and nucleotides.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adipose Tissue; Cell Membrane; Epinephrine; Fluorides; Guanine Nucleotides; Guanosine Triphosphate; Humans; Nucleotides | 1977 |
Epinephrine-and glucagon-sensitive adenylate cyclases of rat liver during aging. Evidence for membrane instability associated with increased enzymatic activity.
Topics: Adenylyl Cyclases; Aging; Animals; Cell Membrane; Dose-Response Relationship, Drug; Epinephrine; Female; Fluorides; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Male; Rats; Sex Factors | 1977 |
Adenylate cyclase activity from normal, malignant and somatic cell hybrid, effect of PGE1, NaF and guanyl nucleotides.
Topics: Adenylyl Cyclases; Cell Line; Enzyme Activation; Fluorides; Guanosine Triphosphate; Hybrid Cells; Kinetics; Prostaglandins E; Sodium Fluoride | 1977 |
Vasopressin-sensitive kidney adenylate cyclase. Differential effects of monovalent ions on stimulation by fluoride, vasopressin and guanylyl 5'-imidodiphosphate.
Topics: Adenylyl Cyclases; Animals; Azides; Cations, Monovalent; Enzyme Activation; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kidney; Kidney Medulla; Kinetics; Oxytocin; Swine; Temperature; Thiocyanates; Vasopressins | 1977 |
Adenylate cyclase activity in hepatic plasma membranes from obese-hyperglycaemic mice [proceedings].
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Fluorides; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hyperglycemia; Liver; Mice; Mice, Obese | 1977 |
Adenylate cyclase activity of normal and goitrous rat thyroids.
Topics: Adenylyl Cyclases; Animals; Calcium; Fluorides; Goiter; Guanosine Triphosphate; Kinetics; Magnesium; Male; Manganese; Propylthiouracil; Prostaglandins E; Rats; Thyroid Gland | 1977 |
Activation by GTP of liver adenylate cyclase in the presence of high concentrations of ATP.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Fluorides; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Rats | 1976 |
Effects of prostaglandins and catecholamines on rat spleen adenylate cyclase in vitro.
Topics: Adenylyl Cyclases; Enzyme Activation; Fluorides; Guanosine Triphosphate; Isoproterenol; Kinetics; Prostaglandins E; Prostaglandins F; Spleen | 1976 |
Two soluble forms of guanosine 5'-(beta,gamma-imino)triphosphate and fluoride-activated adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Dogs; Drug Stability; Enzyme Activation; Fluorides; Guanosine Triphosphate; Isoenzymes; Kidney; Kinetics; Solubility | 1976 |
Cholera toxin and adenylate cyclase: properties of the activated enzyme in liver plasma membranes.
Topics: Adenylyl Cyclases; Animals; Bacterial Toxins; Cell Membrane; Enzyme Activation; Epinephrine; Fluorides; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Magnesium; Male; Mice; Prostaglandins E; Vibrio cholerae | 1976 |
Regulation of adenylate cyclase in two rat liver cell lines, 3C4 and 62.
Topics: Adenylyl Cyclases; Animals; Cell Line; Culture Media; Epinephrine; Fluorides; Glucagon; Guanosine Triphosphate; Kinetics; Prostaglandins A; Prostaglandins E; Rats | 1976 |
Activation of adenylate cyclase by phosphoramidate and phosphonate analogs of GTP: possible role of covalent enzyme-substrate intermediates in the mechanism of hormonal activation.
Topics: Adenylyl Cyclases; Adipose Tissue; Amides; Animals; Chromatography, Affinity; Enzyme Activation; Fluorides; Glucagon; Guanosine Triphosphate; Isoproterenol; Kinetics; Male; Organophosphonates; Rats | 1975 |
Catecholamine stimulated myocardial adenylate cyclase: effects of nucleotides.
Topics: Adenosine Monophosphate; Adenylyl Cyclases; Animals; Cell Membrane; Deoxyribonucleotides; Dogs; Fluorides; Guanine Nucleotides; Guanosine Triphosphate; Heart; Inosine Nucleotides; Isoproterenol; Kinetics; Myocardium; Propranolol; Ribonucleotides; Time Factors | 1975 |
The epinephrine-sensitive adenylate cyclase of rat liver plasma membranes. Role of guanyl nucleotides.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Epinephrine; Female; Fluorides; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Kinetics; Liver; Magnesium; Rats; Structure-Activity Relationship | 1975 |
Charge effects in the activation of adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Cattle; Cell Membrane; Enzyme Activation; Fluorides; Guanosine Triphosphate; Kinetics; Lysine; Magnesium; Muramidase; Peptides; Potassium Chloride; Prostaglandins E; Ribonucleases; Spermidine; Spermine; Thyroid Gland; Thyrotropin | 1975 |
Modulation of meiotic arrest in mouse oocytes by guanyl nucleotides and modifiers of G-proteins.
Topics: Adenylate Cyclase Toxin; Aluminum; Aluminum Compounds; Animals; Bucladesine; Cells, Cultured; Cholera Toxin; Female; Fluorides; Follicle Stimulating Hormone; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hypoxanthine; Hypoxanthines; Mice; Mice, Inbred C57BL; Microinjections; Oogenesis; Ovarian Follicle; Pertussis Toxin; Virulence Factors, Bordetella; Zona Pellucida | 1992 |
Adenylate cyclase from Hirudo medicinalis segmental ganglia: modulation by physiological and non-physiological agents.
Topics: Adenylyl Cyclases; Animals; Fluorides; Ganglia; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Leeches; Serotonin; Thionucleotides | 1992 |
Structural properties of arrestin studied by chemical modification and circular dichroism.
Topics: Adenosine Triphosphate; Animals; Antigens; Arrestin; Calcium Chloride; Cattle; Circular Dichroism; Cysteine; Dithionitrobenzoic Acid; Eye Proteins; Fluorides; Guanosine Triphosphate; Kinetics; Potassium; Potassium Chloride; Potassium Compounds; Protein Conformation | 1992 |
ADP-ribosylation factor, a small GTP-binding protein, is required for binding of the coatomer protein beta-COP to Golgi membranes.
Topics: Adenosine Diphosphate Ribose; ADP-Ribosylation Factors; Animals; CHO Cells; Coatomer Protein; Cricetinae; Fluorides; Golgi Apparatus; GTP-Binding Proteins; Guanosine Triphosphate; In Vitro Techniques; Intracellular Membranes; Macromolecular Substances; Membrane Proteins; Microtubule-Associated Proteins; Protein Binding | 1992 |
The mechanisms of action of lithium. II. Effects on adenylate cyclase activity and beta-adrenergic receptor binding in normal subjects.
Topics: Adenylyl Cyclases; Adult; Affect; Blood Platelets; Cesium; Female; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Lithium; Lithium Carbonate; Lymphocytes; Male; Nerve Tissue Proteins; Norepinephrine; Prospective Studies; Receptors, Adrenergic, beta; Second Messenger Systems; Serotonin; Signal Transduction | 1991 |
Highly variable effects of beryllium and beryllium fluoride on tubulin polymerization under different reaction conditions: comparison of assembly reactions dependent on microtubule-associated proteins, glycerol, dimethyl sulfoxide, and glutamate.
Topics: Animals; Beryllium; Brain; Cattle; Dimethyl Sulfoxide; Fluorides; Glutamates; Glutamic Acid; Glycerol; Guanosine Triphosphate; Kinetics; Macromolecular Substances; Magnesium Sulfate; Microtubule-Associated Proteins; Sodium Fluoride; Tubulin | 1991 |
Mr 40,000 and Mr 39,000 pertussis toxin substrates are increased in surgically denervated dog ventricular myocardium.
Topics: 5'-Nucleotidase; Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Catecholamines; Colforsin; Dogs; Female; Fluorides; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Heart; In Vitro Techniques; Male; Manganese; Membranes; Muscle Denervation; Myocardium; Pertussis Toxin; Phosphorus Radioisotopes; Receptors, Adrenergic, beta; Virulence Factors, Bordetella | 1991 |
Fluoroaluminate treatment of rat liver microsomes inhibits GTP-dependent vesicle fusion.
Topics: Aluminum; Aluminum Compounds; Animals; Calcium; Fluorides; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Membrane Fusion; Microsomes, Liver; Polyethylene Glycols; Rats | 1991 |
Biochemical characterization of three stimulatory GTP-binding proteins. The large and small forms of Gs and the olfactory-specific G-protein, Golf.
Topics: Adenylyl Cyclases; Aluminum; Aluminum Compounds; Animals; Cell Line; Cell Membrane; Central Nervous System; Cholera Toxin; DNA; Enzyme Activation; Fluorides; Fluorine; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Kinetics; Ligands; Macromolecular Substances; Molecular Weight; Olfactory Pathways; Rats; Signal Transduction | 1990 |
G protein control of potassium channel activity in a mast cell line.
Topics: Aluminum; Aluminum Compounds; Animals; Cell Line; Fluorides; Fluorine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Leukemia, Basophilic, Acute; Mast Cells; Neural Conduction; Potassium Channels; Rats; Thionucleotides | 1990 |
Involvement of GTP-binding proteins in actin polymerization in human neutrophils.
Topics: Actins; Aluminum; Aluminum Compounds; Aminoquinolines; Calcium; Cytosol; Fluorescent Dyes; Fluorides; Fluorine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Humans; In Vitro Techniques; Kinetics; Macromolecular Substances; Neutrophils; Thionucleotides; Type C Phospholipases | 1990 |
Synthesis of platelet-activating factor by endothelial cells. The role of G proteins.
Topics: Aluminum; Aluminum Compounds; Animals; Biological Transport, Active; Calcium; Cattle; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Fluorides; Fluorine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Humans; Kinetics; Neutrophils; Platelet Activating Factor; Sodium Fluoride; Thionucleotides | 1990 |
The epidermal growth factor receptor is coupled to a phospholipase A2-specific pertussis toxin-inhibitable guanine nucleotide-binding regulatory protein in cultured rat inner medullary collecting tubule cells.
Topics: Adenosine Diphosphate Ribose; Aluminum; Aluminum Compounds; Animals; Calcium; Cells, Cultured; Dinoprostone; Epidermal Growth Factor; ErbB Receptors; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Kidney Medulla; Kidney Tubules; Kidney Tubules, Collecting; Kinetics; Pertussis Toxin; Phosphatidylinositols; Phospholipases; Phospholipases A; Phospholipases A2; Rats; Tetradecanoylphorbol Acetate; Thionucleotides; Virulence Factors, Bordetella | 1990 |
Histamine-H1-receptor-mediated phosphoinositide hydrolysis, Ca2+ signalling and membrane-potential oscillations in human HeLa carcinoma cells.
Topics: Aluminum; Aluminum Compounds; Calcium; Chromatography, High Pressure Liquid; Diglycerides; Enzyme Activation; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; HeLa Cells; Histamine; Humans; Hydrolysis; Kinetics; Membrane Potentials; Periodicity; Phosphatidylinositols; Potassium Channels; Receptors, Histamine H1; Signal Transduction; Thionucleotides; Type C Phospholipases | 1990 |
G protein control of inositol lipids in intact vascular smooth muscle.
Topics: Aluminum; Aluminum Compounds; Animals; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Inositol Phosphates; Muscle, Smooth, Vascular; Norepinephrine; Pertussis Toxin; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Rats; Thionucleotides; Virulence Factors, Bordetella | 1990 |
Alterations in hormone-sensitive adenylate cyclase of cloned rat osteosarcoma cells during long-term culture.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Bone Neoplasms; Calcitonin; Dinoprostone; Fluorides; Guanosine Triphosphate; Hormones; Isoproterenol; Osteosarcoma; Parathyroid Hormone; Rats; Tumor Cells, Cultured | 1986 |
Age related impairment in phosphatidylinositol breakdown of polymorphonuclear granulocytes.
Topics: Adult; Aged; Aging; Aluminum; Aluminum Compounds; Chloroquine; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; N-Formylmethionine Leucyl-Phenylalanine; Neomycin; Neutrophils; Phosphatidylinositols; Thionucleotides; Virulence Factors, Bordetella | 1989 |
An estimate of the number of G regulator proteins activated per excited rhodopsin in living Limulus ventral photoreceptors.
Topics: Animals; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Horseshoe Crabs; Light; Photoreceptor Cells; Retinal Pigments; Rhodopsin; Thionucleotides; Time Factors; Vision, Ocular | 1989 |
Modification of AlF-4- and receptor-stimulated phospholipase C activity by G-protein beta gamma subunits.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Aluminum; Aluminum Compounds; Animals; Brain; Cattle; Colforsin; Enzyme Activation; Erythrocyte Membrane; Female; Fluorides; Fluorine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Kinetics; Macromolecular Substances; Placenta; Pregnancy; Receptors, Purinergic; Thionucleotides; Turkeys; Type C Phospholipases | 1989 |
Coupling of the stimulatory GTP-binding protein Gs to rat synaptic membrane adenylate cyclase is enhanced subsequent to chronic antidepressant treatment.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Antidepressive Agents, Tricyclic; Cerebral Cortex; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney Medulla; Liver; Male; Rats; Rats, Inbred Strains; Signal Transduction; Synaptic Membranes | 1989 |
Calcium and GTP: essential components in vesicular trafficking between the endoplasmic reticulum and Golgi apparatus.
Topics: Aluminum; Aluminum Compounds; Animals; Biological Transport; Calcium; Cell Line; Cytosol; Endoplasmic Reticulum; Fluorides; Golgi Apparatus; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hydrolysis; Kinetics; Membrane Glycoproteins; Thionucleotides; Vesicular stomatitis Indiana virus; Viral Envelope Proteins | 1989 |
Ca2+ influx stimulated by vasopressin is mediated by phosphoinositide hydrolysis in rat smooth muscle cells.
Topics: Animals; Arginine Vasopressin; Calcium; Cell Membrane; Cyclic AMP; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Inositol Phosphates; Muscle, Smooth, Vascular; Neomycin; Pertussis Toxin; Phosphatidylinositols; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Receptors, Vasopressin; Sugar Phosphates; Thionucleotides; Virulence Factors, Bordetella | 1989 |
Guanine nucleotides stimulate hydrolysis of phosphatidyl inositol bis phosphate in human myelin membranes.
Topics: Adenosine Diphosphate Ribose; Aluminum; Aluminum Compounds; Cell Membrane; Fluorides; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Hydrolysis; Myelin Proteins; Myelin Sheath; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phosphoric Diester Hydrolases; Thionucleotides; Tritium | 1989 |
Phorbol ester inhibits polyphosphoinositide phosphodiesterase activity stimulated by either Ca2+, fluoride or GTP analogue in HL60 membranes and in permeabilized HL60 cells.
Topics: Calcium; Cell Membrane; Cell Membrane Permeability; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Protein Kinase C; Tetradecanoylphorbol Acetate; Thionucleotides; Tumor Cells, Cultured | 1989 |
Inhibition of phosphatidylserine synthesis induced by triggering CD2 or the CD3-TCR complex in a human T cell line. Relationships with G proteins and receptors modulation.
Topics: Antibodies, Monoclonal; Antigens, CD; Cell Line; Cholera Toxin; Fluorides; Guanosine Triphosphate; Humans; Lymphocyte Activation; Phosphatidylserines; Receptors, Antigen, T-Cell; T-Lymphocytes; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1989 |
Inositol trisphosphate production in squid photoreceptors. Activation by light, aluminum fluoride, and guanine nucleotides.
Topics: Aluminum; Aluminum Compounds; Animals; Decapodiformes; Fluorides; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Light; Photoreceptor Cells; Sugar Phosphates; Thionucleotides | 1989 |
Mechanism of GTP hydrolysis in tubulin polymerization: characterization of the kinetic intermediate microtubule-GDP-Pi using phosphate analogues.
Topics: Animals; Beryllium; Brain; Fluorides; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Kinetics; Macromolecular Substances; Mathematics; Microtubules; Models, Theoretical; Phosphates; Structure-Activity Relationship; Swine; Tubulin | 1989 |
Involvement of GTP-binding "G" proteins in transport through the Golgi stack.
Topics: Aluminum; Aluminum Compounds; Animals; Biological Transport; Cell Line; Cell-Free System; Fluorides; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Intracellular Membranes; Membrane Glycoproteins; Microscopy, Electron; Thionucleotides; Vesicular stomatitis Indiana virus; Viral Envelope Proteins; Viral Matrix Proteins | 1987 |
Fluoride complexes of aluminium or beryllium act on G-proteins as reversibly bound analogues of the gamma phosphate of GTP.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Aluminum; Aluminum Compounds; Animals; Beryllium; Cattle; Fluorides; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Photoreceptor Cells; Protein Binding; Rod Cell Outer Segment | 1987 |
Inhibition and activation of interleukin 2 synthesis by direct modification of guanosine triphosphate-binding proteins.
Topics: Antigens, Differentiation, T-Lymphocyte; Calcimycin; CD3 Complex; Cell Line; Cholera Toxin; Cyclic AMP; Diglycerides; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Inositol Phosphates; Interleukin-2; Lymphocyte Activation; Pertussis Toxin; Phytohemagglutinins; T-Lymphocytes; Thionucleotides; Virulence Factors, Bordetella | 1988 |
AlF4- reversibly inhibits 'P'-type cation-transport ATPases, possibly by interacting with the phosphate-binding site of the ATPase.
Topics: Adenosine Triphosphatases; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Beryllium; Binding Sites; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Cell Membrane; Chlorides; Deferoxamine; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoenzymes; Magnesium; Magnesium Chloride; Nitrophenols; Organophosphorus Compounds; Phosphates; Sodium Fluoride; Sodium-Potassium-Exchanging ATPase; Swine; Thionucleotides | 1988 |
The new positive inotrope sulmazole inhibits the function of guanine nucleotide regulatory proteins by affecting GTP turnover.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipose Tissue; Animals; Cardiotonic Agents; Cholera Toxin; Colforsin; Cyclic AMP; Fluorides; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Pertussis Toxin; Rats; Rats, Inbred Strains; Virulence Factors, Bordetella | 1988 |
Neural control of adenylate cyclase responsiveness in brown adipose tissue.
Topics: Adenylyl Cyclases; Adipose Tissue, Brown; Animals; Cold Temperature; Fluorides; Guanosine Triphosphate; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Tyrosine 3-Monooxygenase | 1985 |
Developmental changes of beta-adrenergic receptor-linked adenylate cyclase of rat liver.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Binding Sites; Colforsin; Diterpenes; Female; Fluorides; Growth Inhibitors; Guanosine Triphosphate; Iodine Radioisotopes; Liver; Male; Pindolol; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta; Stimulation, Chemical | 1985 |
Isoproterenol-sensitive adenylate cyclase in glomeruli isolated from young and adult rat renal cortex.
Topics: Adenylyl Cyclases; Aging; Alkaline Phosphatase; Animals; Enzyme Activation; Fluorides; gamma-Glutamyltransferase; Guanine Nucleotides; Guanosine Triphosphate; In Vitro Techniques; Isoproterenol; Kidney Cortex; Kidney Glomerulus; Kidney Tubules; Male; Potassium; Potassium Compounds; Propranolol; Rats; Rats, Inbred Strains | 1985 |
Evidence that PGE2 stimulates intestinal epithelial cell adenylate cyclase by a receptor-mediated mechanism.
Topics: Adenylyl Cyclases; Animals; Colforsin; Dinoprostone; Enzyme Activation; Fluorides; Guanosine Triphosphate; In Vitro Techniques; Intestinal Mucosa; Polidocanol; Polyethylene Glycols; Prostaglandins E; Rats; Receptors, Prostaglandin; Receptors, Prostaglandin E; Stimulation, Chemical | 1987 |
Cytosol activator protein from rat reticulocytes requires the stimulatory guanine nucleotide-binding protein for its actions on adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cytosol; Dinoprostone; Enzyme Activation; Erythrocyte Membrane; Fluorides; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Iodocyanopindolol; Isoproterenol; Lymphoma; Pindolol; Prostaglandins E; Proteins; Rats; Receptors, Adrenergic, beta; Reticulocytes | 1985 |
Alterations in components of adenylate cyclase associated with transformation of chicken embryo fibroblasts by Rous sarcoma virus.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Chick Embryo; Cholera Toxin; Colforsin; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Pertussis Toxin; Thionucleotides; Virulence Factors, Bordetella | 1986 |
Effect of Al3+ plus F- on the catecholamine-stimulated GTPase activity of purified and reconstituted Gs.
Topics: Aluminum; Animals; Catecholamines; Fluorides; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Liver; Phosphoric Monoester Hydrolases; Phosphorus Radioisotopes; Rabbits; Thionucleotides | 1986 |
Regulation of neutrophil NADPH oxidase activation in a cell-free system by guanine nucleotides and fluoride. Evidence for participation of a pertussis and cholera toxin-insensitive G protein.
Topics: Cell-Free System; Cholera Toxin; Chromatography, Gel; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Magnesium; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Pertussis Toxin; Receptors, Formyl Peptide; Receptors, Immunologic; Superoxides; Thionucleotides; Time Factors; Virulence Factors, Bordetella | 1987 |
Pathway of phospholipase C activation initiated with platelet-derived growth factor is different from that initiated with vasopressin and bombesin.
Topics: Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Bombesin; Calcium; Cell Membrane Permeability; Cells, Cultured; Chlorides; Enzyme Activation; Fluorides; Fluorine; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Platelet-Derived Growth Factor; Rats; Saponins; Sodium Fluoride; Thionucleotides; Type C Phospholipases; Vasopressins | 1988 |
Guanine nucleotide-independent inhibition of adenylate cyclase by a stimulatory hormone.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Alprostadil; Cell Membrane; Colforsin; Ethylmaleimide; Fluorides; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Thionucleotides; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1988 |
The purified alpha subunits of Go and Gi from bovine brain require beta gamma for association with phospholipid vesicles.
Topics: Aluminum; Animals; Brain Chemistry; Cattle; Centrifugation, Density Gradient; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Macromolecular Substances; Magnesium; Phospholipids; Thionucleotides | 1986 |
The effects on tubulin polymerization and associated guanosine triphosphate hydrolysis of aluminum ion, fluoride and fluoroaluminate species.
Topics: Aluminum; Animals; Cattle; Fluorides; Fluorine; GTP-Binding Proteins; Guanosine Triphosphate; Hydrolysis; Magnesium; Microtubules; Polymers; Tubulin | 1988 |
A mutation that prevents GTP-dependent activation of the alpha chain of Gs.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Aluminum; Aluminum Compounds; Animals; Binding Sites; Cell Membrane; DNA; Fluorides; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Lymphoma; Magnesium; Mice; Mutation; Protein Conformation; Trypsin; Tumor Cells, Cultured | 1988 |
Mechanism of endogenous phosphorylation of microtubule proteins during GTP-induced microtubule assembly and implications for stability of the assembled structures.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cattle; Cerebral Cortex; Fluorides; Guanosine Triphosphate; Kinetics; Microtubule Proteins; Microtubules; Phosphates; Phosphorylation | 1987 |
[Characteristics of histamine-sensitive adenyl cyclase from cells of the gastric mucosa of the rat].
Topics: Adenosine; Adenylyl Cyclases; Animals; Calcium; Fluorides; Gastric Mucosa; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Histamine; Magnesium; Manganese; Rats | 1986 |
Fluoroaluminates activate transducin-GDP by mimicking the gamma-phosphate of GTP in its binding site.
Topics: Aluminum; Aluminum Compounds; Animals; Binding Sites; Cattle; Fluorides; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Light; Membrane Proteins; Phosphates; Photoreceptor Cells; Rod Cell Outer Segment; Sodium Fluoride; Thionucleotides; Transducin | 1985 |
Chymotrypsin selectively decreases forskolin stimulation of adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Chymotrypsin; Colforsin; Erythrocyte Membrane; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Kinetics; Thionucleotides; Turkeys | 1985 |
Multiple defects in the activity of adenylate cyclase from the Drosophila memory mutant rutabaga.
Topics: Abdomen; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Calcium; Colforsin; Diterpenes; Drosophila melanogaster; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Head; Memory; Mutation; Octopamine; Thionucleotides; Thorax | 1985 |
Thyroid-stimulating hormone binding to beef thyroid membranes. Relation to adenylate cyclase activity.
Topics: Adenylyl Cyclases; Animals; Antimetabolites; Binding Sites; Cations, Divalent; Cations, Monovalent; Cattle; Cell Membrane; Centrifugation, Density Gradient; Chlorpromazine; Drug Stability; Fluorides; Gramicidin; Guanosine Triphosphate; Hydrogen-Ion Concentration; Inosine Nucleotides; Iodine Radioisotopes; Kinetics; Macromolecular Substances; Protein Binding; Pyridines; Receptors, Cell Surface; Thyroid Gland; Thyrotropin; Time Factors; Tritium; Valinomycin | 1974 |
Stimulation of intestinal adenyl cyclase by Escherichia coli enterotoxin: comparison of strains from an infant and an adult with diarrhea.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adult; Animals; Cholera; Cyclic AMP; Cyclic GMP; Diarrhea; Diarrhea, Infantile; Enterotoxins; Epithelial Cells; Epithelium; Escherichia coli Infections; Fluorides; Guanosine Triphosphate; Guanylate Cyclase; Humans; Infant; Intestinal Mucosa; Phosphoric Diester Hydrolases; Phosphorus Radioisotopes; Prostaglandins; Temperature; Tritium | 1974 |
Adenylate cyclase activity in isolated rat islets of Langerhans. Effects of agents which alter rates of insulin secretion.
Topics: Adenylyl Cyclases; Animals; Arginine; Epinephrine; Fluorides; Glucagon; Glucose; Glyburide; Guanosine Triphosphate; Hydrogen-Ion Concentration; In Vitro Techniques; Islets of Langerhans; Isoproterenol; Kinetics; Leucine; Male; Norepinephrine; Nucleotides; Phenoxybenzamine; Phosphorus Radioisotopes; Potassium; Propranolol; Prostaglandins; Rats; Xylitol | 1973 |
Adenyl cyclase and "ATPase" in rat corpus luteum. I. Some properties of the enzymes.
Topics: Adenosine Triphosphatases; Adenylyl Cyclases; Animals; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Thin Layer; Corpus Luteum; Cyclic AMP; Drug Combinations; Enzyme Activation; Female; Fluorides; Guanosine Triphosphate; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Magnesium; Nucleotidases; Phosphoric Monoester Hydrolases; Rats; Subcellular Fractions; Tritium | 1971 |
Requirement for guanosine triphosphate in the prostaglandin activation of adenylate cyclase of platelet membranes.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Adenylyl Cyclases; Binding Sites; Blood Platelets; Chemical Phenomena; Chemistry; Cyclic AMP; Enzyme Activation; Fluorides; Guanosine Triphosphate; Humans; Imides; Membranes; Phosphorus Isotopes; Prostaglandins; Structure-Activity Relationship; Tritium | 1972 |
The problem of identifying the glucagon receptor.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Binding Sites; Cell Membrane; Cyclic AMP; Enzyme Activation; Fluorides; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Models, Biological; Rats; Receptors, Cell Surface | 1973 |
Regulation of adenylyl cyclase from isolated pancretic islets by prostaglandins and guanosine 5'-triphosphate.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cyclic AMP; Drug Synergism; Enzyme Activation; Fluorides; Guanosine Triphosphate; Islets of Langerhans; Kinetics; Male; Membranes; Phosphoric Diester Hydrolases; Phosphorus Radioisotopes; Prostaglandins; Rats; Sodium; Structure-Activity Relationship; Tritium | 1974 |
Binding of 5'-guanylyl-imidodiphosphate to turkey erythrocyte membranes and effects on beta-adrenergic-activated adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Cell Membrane; Chromatography, Ion Exchange; Erythrocytes; Fluorides; Guanine Nucleotides; Guanosine Triphosphate; Imides; Isoproterenol; Kinetics; Norepinephrine; Phentolamine; Phosphorus Radioisotopes; Propranolol; Protein Binding; Receptors, Drug; Tritium; Turkeys | 1974 |
Activation of rat adipocyte plasma membrane adenylate cyclase by sodium azide.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adipose Tissue; Animals; Azides; Cell Membrane; Enzyme Activation; Epinephrine; Fluorides; Guanosine Triphosphate; Rats | 1974 |
Oxytocin-sensitive adenylate cyclase in frog bladder epithelial cells. Role of calcium, nucleotides, and other factors in hormonal stimulation.
Topics: Acetates; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Anura; Binding Sites; Calcium; Epithelial Cells; Epithelium; Fluorides; Glycols; Guanosine Triphosphate; Hydrogen-Ion Concentration; Kinetics; Magnesium; Oxytocin; Phosphorus Isotopes; Protein Denaturation; Rana esculenta; Stimulation, Chemical; Tritium; Urinary Bladder | 1972 |
Rat anterior pituitary adenyl cyclase activity. GTP requirement of prostaglandin E1 and E2 and synthetic luteinising hormone-releasing hormone activation.
Topics: Adenylyl Cyclases; Animals; Fluorides; Gonadotropin-Releasing Hormone; Guanosine Triphosphate; In Vitro Techniques; Kinetics; Male; Osmolar Concentration; Phosphorus Radioisotopes; Pituitary Gland; Prostaglandins; Proteins; Rats; Stimulation, Chemical; Time Factors | 1973 |
5'-Guanylylimidodiphosphate, a potent activator of adenylate cyclase systems in eukaryotic cells.
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenal Gland Neoplasms; Adrenal Glands; Allosteric Regulation; Animals; Anura; Cattle; Cell Line; Cell Membrane; Enzyme Activation; Epinephrine; Erythrocytes; Escherichia coli; Fluorides; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Liver; Propranolol; Rats; Salmon; Stimulation, Chemical; Thyroid Gland | 1974 |
A cell-free system for protein synthesis from newly fertilized eggs of Drosophila melanogaster.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Cations, Monovalent; Cell-Free System; Cyclohexanecarboxylic Acids; Dithiothreitol; Drosophila melanogaster; Electrophoresis, Disc; Fluorides; Guanosine Triphosphate; Hydrogen-Ion Concentration; Kinetics; Leucine; Magnesium; Phosphoenolpyruvate; Potassium; Protein Biosynthesis; Subcellular Fractions; Tritium | 1972 |
Activation of thyroid membrane adenylate cyclase by purine nucleotides.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding Sites; Cattle; Cell Membrane; Enzyme Activation; Fluorides; Guanosine Triphosphate; Inosine Nucleotides; Long-Acting Thyroid Stimulator; Nucleotides; Phosphorus Isotopes; Potassium; Prostaglandins; Purine Nucleotides; Thyroid Gland; Thyrotropin; Tritium; Xanthines | 1973 |
The stimulation of hepatic adenylate cyclase by prostaglandin E1.
Topics: Adenylyl Cyclases; Aluminum; Animals; Chromatography; Chromatography, Ion Exchange; Dogs; Enzyme Activation; Fluorides; Glucagon; Guanosine Triphosphate; Kinetics; Liver; Mice; Phosphorus Radioisotopes; Prostaglandins; Rabbits; Rats; Species Specificity | 1973 |
The effect of sodium fluoride, edeine, and cycloheximide on peptide synthesis with reticulocyte ribosomes.
Topics: Amino Acid Sequence; Animals; Anti-Bacterial Agents; Carbon Radioisotopes; Cephalosporins; Cycloheximide; Fluorides; Fusidic Acid; Guanosine Triphosphate; Kinetics; Leucine; Peptide Biosynthesis; Peptides; Polyamines; Protein Biosynthesis; Rabbits; Reticulocytes; Ribosomes; RNA, Transfer; Time Factors; Tritium; Ultracentrifugation; Valine | 1973 |
The effects of nucleotides on the expression of beta-adrenergic adenylate cyclase activity in membranes from turkey erythrocytes.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Catecholamines; Cell Membrane; Erythrocytes; Fluorides; Guanosine Triphosphate; Inosine Nucleotides; Isoproterenol; Kinetics; Nucleotides; Phentolamine; Phosphorus Radioisotopes; Propranolol; Protein Binding; Receptors, Adrenergic; Turkeys | 1974 |
The glucagon-sensitive adenylate cyclase system in plasma membranes of rat liver. VII. Hormonal stimulation: reversibility and dependence on concentration of free hormone.
Topics: Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Allosteric Regulation; Animals; Binding Sites; Cell Membrane; Drug Synergism; Fluorides; Glucagon; Guanosine Triphosphate; Histidine; Iodine Isotopes; Liver; Osmolar Concentration; Phosphorus Isotopes; Rats; Structure-Activity Relationship; Time Factors | 1972 |
Enzymatic activity in tubulin preparations. I. Intrinsic protein kinase activity in lyophilized preparations of tubulin from porcine brain.
Topics: Adenosine Triphosphate; Animals; Brain; Caseins; Colchicine; Electrophoresis; Fluorides; Guanosine Triphosphate; Histones; Hydrogen-Ion Concentration; Kinetics; Microtubules; Nerve Tissue Proteins; Phosphorus Isotopes; Phosphotransferases; Sodium Dodecyl Sulfate; Swine; Urea; Vinblastine | 1972 |
Effect of calcium ion on horse parathyroid gland adenyl cyclase.
Topics: Acetates; Adenylyl Cyclases; Animals; Calcium; Chromatography, Ion Exchange; Enzyme Activation; Epinephrine; Fluorides; Glycols; Guanosine Triphosphate; Horses; Kinetics; Magnesium; Parathyroid Glands; Phosphates; Phosphorus Isotopes; Potassium Chloride; Prostaglandins; Protein Binding; Tritium | 1972 |
Role of GTP in epinephrine and glucagon activation of adenyl cyclase of liver plasma membrane.
Topics: Adenylyl Cyclases; Adrenal Glands; Animals; Cell Membrane; Enzyme Activation; Epinephrine; Female; Fluorides; Glucagon; Guanosine Triphosphate; In Vitro Techniques; Liver; Phosphorus Isotopes; Rats; Tritium | 1972 |
Interaction between Sindbis virus RNA and ribosomes from chick fibroblasts.
Topics: Adenosine Triphosphate; Animals; Arboviruses; Cells, Cultured; Centrifugation, Density Gradient; Chick Embryo; Cyclohexanecarboxylic Acids; Detergents; Fibroblasts; Fluorides; Guanosine Triphosphate; Ribosomes; RNA, Transfer; RNA, Viral; Sindbis Virus; Sodium; Tritium; Uridine | 1971 |
Developmental changes in adenylate cyclase activity in canine myocardium.
Topics: Adenylyl Cyclases; Age Factors; Animals; Cyclic AMP; Dogs; Epinephrine; Female; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Male; Myocardium | 1984 |
Characterization of adenylate cyclase activity in bovine and human corneal epithelium.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cattle; Cornea; Epithelium; Fluorides; Guanosine Triphosphate; Humans; Propranolol; Prostaglandins; Timolol | 1980 |
A dopamine sensitive adenylate cyclase in the salivary glands of Amblyomma americanum (L.).
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Calcium; Dopamine; Female; Fluorides; Guanosine Triphosphate; Magnesium; Salivary Glands; Ticks | 1982 |
Inhibition of cyclic AMP accumulation in dog heart washed particle preparations by aprotinine.
Topics: Animals; Aprotinin; Cyclic AMP; Depression, Chemical; Dogs; Epinephrine; Fluorides; Guanosine Triphosphate; In Vitro Techniques; Myocardium; Trypsin | 1980 |
A hormone-independent rise of adenosine 3',5'-monophosphate desensitizes coupling of beta-adrenergic receptors to adenylate cyclase in rat glioma C6-cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Carrier Proteins; Cholera Toxin; Cyclic AMP; Dihydroalprenolol; Fluorides; Glioma; Guanosine Triphosphate; Isoproterenol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1980 |
An examination of factors affecting the instability of Saccharomyces cerevisiae glucan synthetase in cell free extracts.
Topics: Edetic Acid; Enzyme Activation; Fluorides; Glucosyltransferases; Guanosine Triphosphate; Kinetics; Magnesium; Membrane Proteins; Saccharomyces cerevisiae; Schizosaccharomyces pombe Proteins; Sodium Fluoride; Sucrose; Temperature | 1984 |
Mechanism of desensitization of adenylate cyclase in lutropin. GTP-dependent uncoupling of the receptor.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Chorionic Gonadotropin; Drug Stability; Female; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Luteinizing Hormone; Ovary; Rats; Receptors, Cell Surface | 1980 |
Fluoride stimulation of adenylate cyclase is dependent on the guanine nucleotide regulatory protein.
Topics: Adenylyl Cyclases; Animals; Enzyme Activation; Erythrocyte Membrane; Erythrocytes; Fluorides; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Monophosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Membrane Proteins; Temperature; Turkeys | 1980 |
Characteristics of the guanine nucleotide regulatory component of adenylate cyclase in human erythrocyte membranes.
Topics: Adenylyl Cyclases; Animals; Chemical Phenomena; Chemistry; Cholera Toxin; Erythrocyte Membrane; Erythrocytes; Ethylmaleimide; Fluorides; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Mice; Molecular Weight; NAD; Protein Binding; Rats; Receptors, Adrenergic, beta; Turkeys | 1980 |
Receptor-specific desensitization of the S49 lymphoma cell adenylyl cyclase. Unaltered behavior of the regulatory component.
Topics: Adenylyl Cyclases; Animals; Cell Line; Enzyme Activation; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Lymphoma; Magnesium; Mice; Neoplasms, Experimental; Prostaglandins E; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1981 |
Thyroid membrane ADP ribosyltransferase activity. Stimulation by thyrotropin and activity in functioning and nonfunctioning rat thyroid cells in culture.
Topics: Adenosine Triphosphate; ADP Ribose Transferases; Animals; Cattle; Cell Line; Cell Membrane; Fluorides; Guanosine Triphosphate; Kinetics; NAD+ Nucleosidase; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases; Rats; Thyroid Gland; Thyrotropin | 1981 |
Interactions of fluoride and guanine nucleotides with thyroid adenylate cyclase.
Topics: Adenylate Kinase; Adenylyl Imidodiphosphate; Animals; Cattle; Enzyme Activation; Fluorides; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Phosphotransferases; Sodium Fluoride; Thionucleotides; Thyroid Gland | 1982 |
Vanadate stimulates adenylate cyclase via the guanine nucleotide regulatory protein by a mechanism differing from that of fluoride.
Topics: Adenylyl Cyclases; Animals; Cholera Toxin; Erythrocyte Membrane; Fluorides; GTP-Binding Proteins; Guanosine Triphosphate; Receptors, Cell Surface; Turkeys; Vanadates; Vanadium | 1982 |
Modulation of adenylate cyclase activity by the physical state of pigeon erythrocyte membrane. 2. Fluidity-controlled coupling between the subunits of the adenylate cyclase system.
Topics: 1-Octanol; Adenylyl Cyclases; Animals; Chlorpromazine; Columbidae; Electron Spin Resonance Spectroscopy; Enzyme Activation; Erythrocyte Membrane; Erythrocytes; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Membrane Fluidity; Octanols | 1982 |
Characteristics of the guanine nucleotide-binding regulatory component of adenylate cyclase.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Blood Proteins; Cell Membrane; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Mathematics; Receptors, Cell Surface; Thionucleotides | 1982 |
Magnesium regulation of the beta-receptor-adenylate cyclase complex. II. Sc3+ as a Mg2 antagonist.
Topics: Adenylyl Cyclase Inhibitors; Animals; Binding Sites; Fluorides; Guanosine Triphosphate; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Lanthanum; Magnesium; Mice; Receptors, Adrenergic; Receptors, Adrenergic, beta; Scandium | 1982 |
Effects of experimental insulin-dependent diabetes on the beta-adrenergic-receptor-coupled adenylate-cyclase system and lipolysis in fat cells of the rat.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Cyclic AMP; Diabetes Mellitus, Experimental; Fluorides; Guanosine Triphosphate; Insulin; Isoproterenol; Lipolysis; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1983 |
The subunits of the stimulatory regulatory component of adenylate cyclase. Resolution of the activated 45,000-dalton (alpha) subunit.
Topics: Adenylyl Cyclases; Aluminum; Animals; Chromatography, Gel; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Macromolecular Substances; Magnesium; Molecular Weight; Rabbits; Receptors, Cell Surface; Thionucleotides | 1983 |
Chemical excitation of Limulus photoreceptors. II. Vanadate, GTP-gamma-S, and fluoride prolong excitation evoked by dim flashes of light.
Topics: Animals; Evoked Potentials, Visual; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Horseshoe Crabs; Models, Biological; Phosphoric Monoester Hydrolases; Photic Stimulation; Photoreceptor Cells; Stimulation, Chemical; Thionucleotides; Vanadates; Vanadium | 1983 |
Beta-adrenergic regulation of Sertoli cell adenylyl cyclase: desensitization by homologous hormone.
Topics: Adenylyl Cyclases; Animals; Bucladesine; Cyclic AMP; Dose-Response Relationship, Drug; Fluorides; Follicle Stimulating Hormone; Guanosine Triphosphate; Isoproterenol; Kinetics; Male; Rats; Receptors, Adrenergic, beta; Sertoli Cells | 1984 |
Effects of proteolytic enzymes and protease inhibitors on bovine thyroid adenylate cyclase activity.
Topics: Adenylyl Cyclases; Animals; Cations, Divalent; Cattle; Cell Membrane; Cholera Toxin; Chymotrypsin; Endopeptidases; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Papain; Protease Inhibitors; Thyroid Gland; Thyrotropin; Trypsin | 1983 |
Excitation of Limulus photoreceptors by vanadate and by a hydrolysis-resistant analog of guanosine triphosphate.
Topics: Action Potentials; Adenylyl Cyclases; Animals; Carrier Proteins; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Horseshoe Crabs; Photoreceptor Cells; Thionucleotides; Vanadates; Vanadium | 1981 |
Changes in pH sensitivity of adenylate cyclase specifically induced by fluoride and vanadate.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Enzyme Activation; Fluorides; Glucagon; Guanosine Triphosphate; Hydrogen-Ion Concentration; Liver; Magnesium; Manganese; Rats; Sodium Fluoride; Vanadates; Vanadium | 1982 |
Purification of the regulatory component of adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cholera Toxin; Fluorides; Guanosine Triphosphate; Liver; Macromolecular Substances; Molecular Weight; NAD; Rabbits | 1980 |
Proteolysis of skeletal muscle adenylate cyclase. Destruction and reconstitution of fluoride and guanylnucleotide sensitivity.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Ethylmaleimide; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Muscles; Rabbits; Sodium Fluoride; Subtilisins | 1980 |
[Effects of GTP and NaF on rabbit heart adenylate cyclase activated by guanyl-5'-ilimidodiphosphate].
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Enzyme Activation; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Myocardium; Rabbits; Sodium Fluoride | 1980 |
Effects of thiol-protecting reagents on the size of solubilized adenylate cyclase and on its ability to be stimulated by guanyl nucleotides and fluoride.
Topics: Adenylyl Cyclases; Animals; Brain; Chromatography, Gel; Fluorides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kidney Medulla; Liver; Mercaptoethanol; Octoxynol; Polyethylene Glycols; Rats; Sodium Fluoride; Solubility; Swine; Ultracentrifugation | 1981 |
The role of guanine nucleotides in regulation of adenylate cyclase activity.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cholera Toxin; Enzyme Activation; Erythrocyte Membrane; Erythrocytes; Fluorides; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Pseudohypoparathyroidism; Rats; Reticulocytes; Turkeys | 1981 |
Hysteretic activation of adenylyl cyclases. I. Effect of Mg ion on the rate of activation by guanine nucleotides and fluoride.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Fluorides; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Liver; Magnesium; Rats; Sodium Fluoride | 1981 |
Modulation of adenylate cyclase in intact macrophages by microtubules. Opposing actions of colchicine and chemotactic factor.
Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Cholera Toxin; Colchicine; Fluorides; Guanosine Triphosphate; Guinea Pigs; Isoproterenol; Macrophages; Male; Methionine; Microtubules; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Prostaglandins E; Vinblastine | 1980 |
Preactivation as a determinant for the size of thyroid adenylate cyclase.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Cattle; Cell Membrane; Cholera Toxin; Enzyme Activation; Fluorides; Guanosine Triphosphate; Manganese; Molecular Weight; Thyroid Gland | 1980 |
Activation of bovine luteal adenylate cyclase by human choriogonadotropin in vitro: persistence of the activated state following preactivation and washing [proceedings].
Topics: Adenylyl Cyclases; Animals; Cattle; Cell Membrane; Chorionic Gonadotropin; Corpus Luteum; Enzyme Activation; Female; Fluorides; Guanosine Triphosphate | 1980 |
ATP-operated calcium-permeable channels activated via a guanine nucleotide-dependent mechanism in rat macrophages.
Topics: Adenosine Triphosphate; Animals; Calcium Channels; Cations; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Ion Channels; Macrophages; Male; Rats; Rats, Wistar | 1995 |
Olfactory transduction mechanisms in sheep.
Topics: Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Epithelium; Ethylamines; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Inositol Phosphates; Kinetics; Odorants; Olfactory Mucosa; Sheep; Signal Transduction; Smell | 1995 |
Mg2+-dependent phosphatase as an inhibitory mediator of the nonselective cation current induced by aluminum fluoride in guinea-pig chromaffin cells.
Topics: Aluminum Compounds; Animals; Cations; Chromaffin System; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guinea Pigs; Ion Channels; Magnesium; Muscarine; Muscarinic Agonists; Patch-Clamp Techniques; Phosphoprotein Phosphatases; Protein Phosphatase 2C | 1995 |
Involvement of heterotrimeric GTP-binding protein and rho protein, but not protein kinase C, in agonist-induced Ca2+ sensitization of skinned muscle of guinea pig vas deferens.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Aluminum Compounds; Animals; Botulinum Toxins; Calcium; Escin; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Peptides; Phorbol 12,13-Dibutyrate; Protein Kinase C; rho GTP-Binding Proteins; Vas Deferens | 1995 |
Glutamate activates a K+ conductance increase in Aplysia neurons that appears to be independent of G proteins.
Topics: Animals; Aplysia; Beryllium; Cholinergic Agonists; Dialysis; Electric Conductivity; Excitatory Amino Acid Agonists; Fluorides; Glutamic Acid; GTP-Binding Proteins; Guanosine Triphosphate; Neurons; Pertussis Toxin; Potassium; Virulence Factors, Bordetella | 1994 |
Mechanism of GTP hydrolysis by G-protein alpha subunits.
Topics: Aluminum Compounds; Amino Acid Sequence; Base Sequence; Conserved Sequence; DNA; Escherichia coli; Fluorides; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Hydrolysis; Kinetics; Macromolecular Substances; Magnesium; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phosphorus Radioisotopes; Proto-Oncogene Proteins p21(ras); Recombinant Proteins; Signal Transduction; Time Factors | 1994 |
Beta-adrenergic receptor overexpression in the fetal rat: distribution, receptor subtypes, and coupling to adenylate cyclase activity via G-proteins.
Topics: Adenylyl Cyclases; Analysis of Variance; Animals; Autoradiography; Fetus; Fluorides; Gene Expression Regulation, Developmental; Gestational Age; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Tissue Distribution | 1994 |
Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis.
Topics: Aluminum Compounds; Arginine; Binding Sites; Catalysis; Computer Graphics; Crystallography, X-Ray; Fluorides; Glutamine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Helix-Loop-Helix Motifs; Hydrogen Bonding; Hydrolysis; Models, Molecular; Protein Conformation; Protein Structure, Secondary | 1994 |
Aluminum fluoride and magnesium, activators of heterotrimeric GTP-binding proteins, affect high-affinity binding of the fungal toxin fusicoccin to the fusicoccin-binding protein in oat root plasma membranes.
Topics: Acetone; Aluminum Compounds; Binding Sites; Cell Membrane; Edible Grain; Fluorides; Glucosides; Glycosides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Magnesium; Plant Proteins; Receptors, Cell Surface; Signal Transduction; Sodium Fluoride | 1994 |
G proteins activate ATP-sensitive K+ channels by antagonizing ATP-dependent gating.
Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Aluminum Compounds; Animals; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guinea Pigs; Inosine Diphosphate; Ion Channel Gating; Potassium Channels; Thionucleotides; Uridine Diphosphate | 1994 |
Aluminum fluoride acts on the reversibility of ARF1-dependent coat protein binding to Golgi membranes.
Topics: ADP-Ribosylation Factor 1; ADP-Ribosylation Factors; Aluminum Compounds; Animals; Cattle; CHO Cells; Coatomer Protein; Cricetinae; Cytosol; Fluorides; Golgi Apparatus; GTP-Binding Proteins; Guanosine Triphosphate; Hydrolysis; Membrane Proteins; Protein Binding | 1994 |
Glucocorticoids regulate the development of intracellular signaling: enhanced forebrain adenylate cyclase catalytic subunit activity after fetal dexamethasone exposure.
Topics: Adenylyl Cyclases; Aging; Analysis of Variance; Animals; Body Weight; Colforsin; Dexamethasone; Female; Fluorides; Gestational Age; GTP-Binding Proteins; Guanosine Triphosphate; Macromolecular Substances; Maternal-Fetal Exchange; Membrane Proteins; Pregnancy; Prosencephalon; Rats; Rats, Sprague-Dawley; Weight Gain | 1993 |
Tryptophan W207 in transducin T alpha is the fluorescence sensor of the G protein activation switch and is involved in the effector binding.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Aluminum Compounds; Amino Acid Sequence; Animals; Baculoviridae; DNA Mutational Analysis; Enzyme Activation; Fluorescence; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Models, Molecular; Molecular Sequence Data; Moths; Protein Conformation; Recombinant Proteins; Rod Cell Outer Segment; Sequence Homology, Amino Acid; Signal Transduction; Transducin; Tryptophan | 1993 |
Agonist-induced, GTP-dependent phosphoinositide hydrolysis in postmortem human brain membranes.
Topics: Adenosine Triphosphate; Aged; Aluminum Compounds; Brain; Calcium; Carbachol; Cell Membrane; Cycloleucine; Female; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Histamine; Humans; Hydrolysis; Male; Neurotoxins; Phosphatidylinositols; Pilocarpine; Postmortem Changes; Second Messenger Systems; Serotonin; Type C Phospholipases | 1994 |
A GTP-dependent step in the activation mechanism of capacitative calcium influx.
Topics: Aluminum Compounds; Animals; Biological Transport; Calcium; Calcium Channels; Cell Membrane; Egtazic Acid; Fluorides; Guanosine Triphosphate; Indicators and Reagents; Inositol 1,4,5-Trisphosphate; Ion Channel Gating; Ionomycin; Rats; Tumor Cells, Cultured | 1993 |
Multiple GTP-binding proteins participate in clathrin-coated vesicle-mediated endocytosis.
Topics: Aluminum; Aluminum Compounds; Amino Acid Sequence; Coated Pits, Cell-Membrane; Endocytosis; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Humans; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Molecular Sequence Data; Peptides; Receptors, Transferrin; Thionucleotides; Tumor Cells, Cultured; Wasp Venoms | 1993 |
A functional role for GTP-binding proteins in synaptic vesicle cycling.
Topics: Aluminum; Aluminum Compounds; Animals; Calcium; Decapodiformes; Fluorides; Fluorine; Ganglia; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; In Vitro Techniques; Kinetics; Models, Neurological; Nerve Endings; Signal Transduction; Synaptic Vesicles; Thionucleotides; Time Factors | 1993 |
Thermodynamics of tubulin polymerization into zinc sheets: assembly is not regulated by GTP hydrolysis.
Topics: Aluminum; Aluminum Compounds; Animals; Beryllium; Brain; Colchicine; Fluorides; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Microscopy, Electron; Polymers; Rats; Subtilisins; Swine; Temperature; Thermodynamics; Tubulin; Zinc | 1993 |
Adrenergic desensitization in left ventricle from streptozotocin diabetic swine.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aluminum; Animals; Blood Glucose; Colforsin; Cyclic AMP; Cytosol; Diabetes Mellitus, Experimental; Fluorides; GTP-Binding Proteins; Guanosine Triphosphate; Heart Ventricles; Insulin; Isoproterenol; Receptors, Adrenergic, beta; Sarcolemma; Signal Transduction; Streptozocin; Swine; Swine, Miniature | 1995 |
Nonhydrolyzable analogues of GTP activate a new Na+ current in a rat mast cell line.
Topics: Animals; Biological Transport; Cell Membrane Permeability; Cell Polarity; Electric Conductivity; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hydrolysis; Mast Cells; Patch-Clamp Techniques; Rats; Second Messenger Systems; Sodium; Sodium Channels; Thionucleotides; Tumor Cells, Cultured | 1996 |
Bidirectional regulation of neuronal potassium currents by the G-protein activator aluminum fluoride as a function of intracellular calcium concentration.
Topics: Aluminum Compounds; Animals; Calcium; Electrophysiology; Fluorides; Ganglia, Invertebrate; GTP-Binding Proteins; Guanosine Triphosphate; In Vitro Techniques; Ion Channel Gating; Iontophoresis; Membrane Potentials; Mollusca; Neurons; Patch-Clamp Techniques; Photoreceptor Cells; Potassium Channels | 1996 |
The GTPase-activating protein RGS4 stabilizes the transition state for nucleotide hydrolysis.
Topics: Aluminum Compounds; Animals; Fluorides; GTP Phosphohydrolases; GTP-Binding Proteins; GTPase-Activating Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Kinetics; Mammals; Proteins; Recombinant Proteins; RGS Proteins | 1996 |
Effect of morphine on secretion of amylase from isolated parotid acini.
Topics: Affinity Labels; Aluminum Compounds; Amylases; Animals; Azides; Bacterial Toxins; Bucladesine; Cyclic AMP; Fluorides; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hemolysin Proteins; In Vitro Techniques; Morphine; Neurotoxins; Parotid Gland; Rats; Rats, Sprague-Dawley | 1996 |
Simple purification and functional reconstitution of octopus photoreceptor Gq, which couples rhodopsin to phospholipase C.
Topics: Aluminum Compounds; Amino Acid Sequence; Animals; Brain; Cattle; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanosine Triphosphate; Light; Liposomes; Molecular Sequence Data; Octopodiformes; Photoreceptor Cells, Invertebrate; Protein Binding; Protein Conformation; Rhodopsin; Sequence Analysis; Sequence Homology, Amino Acid; Type C Phospholipases | 1996 |
Beta-adrenoceptor control of cardiac adenylyl cyclase during development: agonist pretreatment in the neonate uniquely causes heterologous sensitization, not desensitization.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Female; Fluorides; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Male; Myocardium; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta | 1995 |
Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysis.
Topics: Aluminum Compounds; Amino Acid Sequence; Animals; Binding Sites; Crystallography, X-Ray; Fluorides; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Magnesium; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Conformation; Proteins; Rats; RGS Proteins | 1997 |
Relationship between specific binding of 125I-omega-conotoxin GVIA and GTP binding protein: effects of the GTP analogues, mastoparan and A1F4-.
Topics: Aluminum Compounds; Animals; Brain; Chickens; Fluorides; GTP-Binding Proteins; Guanosine Triphosphate; Intercellular Signaling Peptides and Proteins; Iodine Radioisotopes; omega-Conotoxin GVIA; Peptides; Wasp Venoms | 1997 |
The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants.
Topics: Aluminum Compounds; Amino Acid Sequence; Binding Sites; Catalysis; Cell Transformation, Neoplastic; Crystallography, X-Ray; Enzyme Activation; Fluorides; GTP Phosphohydrolases; GTP-Binding Proteins; GTPase-Activating Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Models, Molecular; Molecular Sequence Data; Mutation; Protein Conformation; Protein Structure, Secondary; Proteins; ras GTPase-Activating Proteins; ras Proteins; Signal Transduction | 1997 |
Interaction of human retinal RGS with G-protein alpha-subunits.
Topics: Aluminum Compounds; Animals; Cattle; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Eye Proteins; Fluorides; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Protein Binding; Protein Conformation; Recombinant Fusion Proteins; RGS Proteins; Rod Cell Outer Segment; Transducin; Trypsin | 1997 |
Equilibrium and kinetic study of the conformational transition toward the active state of p21Ha-ras, induced by the binding of BeF3- to the GDP-bound state, in the absence of GTPase-activating proteins.
Topics: Anions; Beryllium; Flow Injection Analysis; Fluorides; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Models, Chemical; Mutation; Phosphates; Protein Conformation; Proto-Oncogene Proteins p21(ras); Recombinant Proteins; Spectrometry, Fluorescence | 1997 |
Chemotactic peptide-induced activation of Ras in human neutrophils is associated with inhibition of p120-GAP activity.
Topics: Adaptor Proteins, Signal Transducing; Calcium; Fluorides; GRB2 Adaptor Protein; GTP-Binding Protein alpha Subunits, Gi-Go; GTPase-Activating Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neurofibromin 1; Neutrophils; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Precipitin Tests; Protein-Tyrosine Kinases; Proteins; ras GTPase-Activating Proteins; ras Proteins; Signal Transduction; Son of Sevenless Proteins; Type C Phospholipases; Virulence Factors, Bordetella | 1997 |
ATP-dependent desensitization of the muscarinic K+ channel in rat atrial cells.
Topics: Acetylcholine; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Electrophysiology; Fluorides; Guanosine Triphosphate; Heart Atria; Male; Myocardium; Patch-Clamp Techniques; Phosphoric Monoester Hydrolases; Phosphorylation; Potassium Channels; Rats; Receptors, Muscarinic; Vanadates; Zinc | 1997 |
Fluoride activation of the Rho family GTP-binding protein Cdc42Hs.
Topics: Aluminum Compounds; cdc42 GTP-Binding Protein; Cell Cycle Proteins; Chromatography, Gel; Fluorescence Polarization; Fluorides; GTP-Binding Proteins; GTPase-Activating Proteins; Guanosine Triphosphate; Hydrolysis; Magnetic Resonance Spectroscopy; Protein Binding; Proteins; ras GTPase-Activating Proteins | 1998 |
Protein kinase A regulates the disposition of Ca2+ which enters the cytoplasmic space through store-activated Ca2+ channels in rat hepatocytes by diverting inflowing Ca2+ to mitochondria.
Topics: Adenosine Triphosphate; Aluminum Compounds; Animals; Bucladesine; Calcium; Calcium Channels; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoplasm; Enzyme Inhibitors; Fluorides; Genistein; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Liver; Mitochondria, Liver; Rats; Thapsigargin; Vasopressins | 1998 |
GAP into the breach.
Topics: Aluminum Compounds; Binding Sites; Catalysis; Crystallography, X-Ray; Fluorides; GTP Phosphohydrolases; GTP-Binding Proteins; GTPase-Activating Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Models, Molecular; Protein Conformation; Protein Structure, Secondary; Proteins; ras GTPase-Activating Proteins; ras Proteins; RGS Proteins | 1997 |
Stimulation of rat liver mitochondrial fusion by an outer membrane-derived aluminum fluoride-sensitive protein fraction.
Topics: Aluminum Compounds; Animals; Cell Compartmentation; Fluorides; GTP-Binding Proteins; Guanosine Triphosphate; Intracellular Membranes; Liver; Membrane Fusion; Microscopy, Confocal; Mitochondria; Rats; Signal Transduction | 1998 |
Mutations at the domain interface of GSalpha impair receptor-mediated activation by altering receptor and guanine nucleotide binding.
Topics: Adenylyl Cyclases; Aluminum Compounds; Binding, Competitive; Enzyme Activation; Fluorides; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Iodocyanopindolol; Isoproterenol; Models, Molecular; Mutation; Pindolol; Protein Binding; Protein Structure, Secondary; Receptors, Adrenergic, beta; Transfection; Tumor Cells, Cultured | 1998 |
A putative heterotrimeric G protein inhibits the fusion of COPI-coated vesicles. Segregation of heterotrimeric G proteins from COPI-coated vesicles.
Topics: Aluminum Compounds; Animals; Cell Line; Chromogranins; Coated Vesicles; Coatomer Protein; Detergents; Fluorides; Golgi Apparatus; Green Fluorescent Proteins; GTP-Binding Proteins; Guanosine Triphosphate; Luminescent Proteins; Membrane Fusion; Membrane Proteins; Microscopy, Fluorescence; Protein Conformation; Solubility; Transfection | 1998 |
p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13.
Topics: Aluminum Compounds; Amino Acid Sequence; Animals; Fluorides; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, G12-G13; GTP-Binding Proteins; Guanine Nucleotide Exchange Factors; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Humans; Hydrolysis; Molecular Sequence Data; Proteins; Recombinant Fusion Proteins; Sequence Alignment; Signal Transduction | 1998 |
Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13.
Topics: Aluminum Compounds; Animals; COS Cells; Fluorides; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, G12-G13; GTP-Binding Proteins; Guanine Nucleotide Exchange Factors; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Proteins; Recombinant Fusion Proteins; Recombinant Proteins; Signal Transduction | 1998 |
Glucocorticoid-targeting of the adenylyl cyclase signaling pathway in the cerebellum of young vs. aged rats.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Anti-Inflammatory Agents; Cerebellum; Colforsin; Dexamethasone; Fluorides; Glucocorticoids; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Kidney; Male; Manganese; Rats; Rats, Sprague-Dawley; Signal Transduction | 1998 |
Identification of effector residues on photoreceptor G protein, transducin.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Aluminum Compounds; Amino Acid Sequence; Animals; Cattle; Fluorides; GTP Phosphohydrolases; GTPase-Activating Proteins; Guanosine Triphosphate; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Protein Structure, Secondary; Proteins; Structure-Activity Relationship; Transducin | 1998 |
Negative regulation of Rho family GTPases Cdc42 and Rac2 by homodimer formation.
Topics: Aluminum Compounds; cdc42 GTP-Binding Protein, Saccharomyces cerevisiae; Cell Cycle Proteins; Dimerization; Fluorides; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Humans; ortho-Aminobenzoates; rac GTP-Binding Proteins; ras Proteins; rhoA GTP-Binding Protein; Sequence Alignment; Signal Transduction; Spectrometry, Fluorescence | 1998 |
The thrombospondin receptor integrin-associated protein (CD47) functionally couples to heterotrimeric Gi.
Topics: Aluminum Compounds; Antigens, CD; Carrier Proteins; CD47 Antigen; Cyclic AMP; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Membrane Proteins; Peptide Fragments; Precipitin Tests; Protein Binding; Receptors, Vitronectin; Thrombospondins; Tumor Cells, Cultured | 1999 |
Agonist-induced translocation of Gq/11alpha immunoreactivity directly from plasma membrane in MDCK cells.
Topics: Aluminum Compounds; Animals; Biological Transport; Bradykinin; Cell Line; Cell Membrane; Dogs; Fluorescent Antibody Technique; Fluorides; GTP-Binding Proteins; Guanosine Triphosphate; Kidney; Microscopy, Confocal | 1999 |
Nucleotide-binding characteristics of human guanylate-binding protein 1 (hGBP1) and identification of the third GTP-binding motif.
Topics: Aluminum Compounds; Binding Sites; Binding, Competitive; Calorimetry; DNA-Binding Proteins; Fluorides; Fluorometry; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Monophosphate; Guanosine Triphosphate; Humans; Kinetics; Magnetic Resonance Spectroscopy; Mutation; Recombinant Proteins; Thermodynamics | 1999 |
Reaction dynamics of G-protein catalyzed hydrolysis of GTP as viewed by X-ray crystallographic snapshots of Gi alpha 1.
Topics: Aluminum Compounds; Binding Sites; Crystallography, X-Ray; Fluorides; GTP Phosphohydrolases; GTP-Binding Proteins; GTPase-Activating Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Hydrogen Bonding; Models, Molecular; Protein Binding; Protein Conformation; Proteins; Signal Transduction | 1999 |
Hydrolysis of nucleoside triphosphates other than ATP by nitrogenase.
Topics: Adenosine Triphosphate; Aluminum Compounds; Azotobacter vinelandii; Bacterial Proteins; Clostridium; Dithionite; Fluorides; Guanosine Triphosphate; Inosine Triphosphate; Kinetics; Molybdoferredoxin; Nitrogenase; Nucleotides; Oxidation-Reduction; Oxidoreductases; Uridine Triphosphate | 2000 |
Biochemical characterization of Rab3-GTPase-activating protein reveals a mechanism similar to that of Ras-GAP.
Topics: Aluminum Compounds; Amino Acid Sequence; Animals; Arginine; Binding Sites; Calcium; Calmodulin; Catalysis; Fluorides; GTP-Binding Proteins; GTPase-Activating Proteins; Guanine Nucleotides; Guanosine Triphosphate; Kinetics; Molecular Sequence Data; Mutation; Protein Binding; rab3 GTP-Binding Proteins; rab3A GTP-Binding Protein; ras GTPase-Activating Proteins; Recombinant Fusion Proteins; Sequence Alignment; Substrate Specificity; Thermodynamics | 2000 |
Arabidopsis RopGAPs are a novel family of rho GTPase-activating proteins that require the Cdc42/Rac-interactive binding motif for rop-specific GTPase stimulation.
Topics: Aluminum Compounds; Arabidopsis; Binding Sites; Binding, Competitive; cdc42 GTP-Binding Protein; DNA, Complementary; Fluorides; GTPase-Activating Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Mutation; Protein Binding; Sequence Alignment; Sequence Analysis, DNA; Sequence Deletion | 2000 |
Apical heterotrimeric g-proteins activate CFTR in the native sweat duct.
Topics: Adenosine Triphosphate; Adult; Aluminum Compounds; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Heterotrimeric GTP-Binding Proteins; Humans; Immunohistochemistry; In Vitro Techniques; Male; Mutation; Sodium Channels; Sodium-Potassium-Exchanging ATPase; Sweat Glands | 2001 |
Biochemical analysis of yeast G(alpha) mutants that enhance adaptation to pheromone.
Topics: Adaptation, Physiological; Alleles; Aluminum Compounds; Amino Acid Substitution; Binding Sites; Chromatography, Affinity; Down-Regulation; Fluorides; GTP-Binding Protein alpha Subunits; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Heterotrimeric GTP-Binding Proteins; Histidine; Models, Molecular; Mutation; Pheromones; Protein Binding; Receptors, Mating Factor; Receptors, Peptide; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Transcription Factors | 2001 |
Characterization of GTP binding and hydrolysis in plasma membranes of zucchini.
Topics: Aluminum; Cell Membrane; Detergents; Fluorides; GTP Phosphohydrolases; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Triphosphate; Hydrolysis; Hypocotyl; Magnesium; Membrane Proteins; Protein Binding; Signal Transduction; Vegetables | 1992 |
Determination of the size and chemical nature of the stabilizing "cap" at microtubule ends using modulators of polymerization dynamics.
Topics: Aluminum Compounds; Animals; Beryllium; Binding Sites; Brain Chemistry; Cattle; Fluorides; Guanosine Diphosphate; Guanosine Triphosphate; Male; Microscopy, Video; Microtubules; Phosphates; Phosphorus Radioisotopes; Polymers; Sea Urchins; Spermatozoa; Thermodynamics; Tubulin | 2002 |
Self-assembly of human MxA GTPase into highly ordered dynamin-like oligomers.
Topics: Aluminum Compounds; Dimerization; Dynamins; Escherichia coli; Fluorides; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Microscopy, Electron; Myxovirus Resistance Proteins; Protein Binding; Protein Conformation; Proteins; Recombinant Proteins; Salts | 2002 |
S111N mutation in the helical domain of human Gs(alpha) reduces its GDP/GTP exchange rate.
Topics: Adenylyl Cyclases; Aluminum Compounds; Amino Acid Substitution; Asparagine; Fluorides; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Humans; Models, Molecular; Point Mutation; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Cell Surface; Serine; Trypsin | 2002 |
The GTPase-activating protein Rap1GAP uses a catalytic asparagine.
Topics: Adenosine Diphosphate; Aluminum Compounds; Asparagine; Binding Sites; Catalysis; Catalytic Domain; Crystallography, X-Ray; Fluorides; GTPase-Activating Proteins; Guanosine Triphosphate; Humans; Hydrolysis; Models, Molecular; Mutation; Protein Conformation; rap1 GTP-Binding Proteins; Repressor Proteins; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins | 2004 |
Uncoupling of GPCR and RhoA-induced Ca2+-sensitization of chicken amnion smooth muscle lacking CPI-17.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aluminum Compounds; Amnion; Animals; Bacterial Toxins; Calcium; Chickens; Cyclic GMP; Enzyme Activation; Enzyme Inhibitors; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Muscle Contraction; Muscle Proteins; Muscle, Smooth; Myosin-Light-Chain Phosphatase; Phosphoprotein Phosphatases; Phosphoproteins; Protein Phosphatase 1; Protein Subunits; Receptors, G-Protein-Coupled; rhoA GTP-Binding Protein; Signal Transduction; Vasoconstrictor Agents | 2004 |
Visualization of single Escherichia coli FtsZ filament dynamics with atomic force microscopy.
Topics: Adsorption; Aluminum Compounds; Aluminum Silicates; Chemical Phenomena; Chemistry, Physical; Escherichia coli; Escherichia coli Proteins; Fluorides; Guanosine Diphosphate; Guanosine Triphosphate; Hydrogen-Ion Concentration; Microscopy, Atomic Force; Polymers; Solutions | 2005 |
Golgi targeting of human guanylate-binding protein-1 requires nucleotide binding, isoprenylation, and an IFN-gamma-inducible cofactor.
Topics: Alkyl and Aryl Transferases; Aluminum Compounds; Blotting, Western; Cell Fractionation; Cloning, Molecular; Farnesyltranstransferase; Fluorescent Antibody Technique; Fluorides; Genetic Vectors; Golgi Apparatus; GTP-Binding Proteins; Guanosine Triphosphate; HeLa Cells; Humans; Immunoprecipitation; Interferon-gamma; Methionine; Mutagenesis; Mutation; Protein Prenylation; Protein Transport; Retroviridae; Transduction, Genetic | 2005 |
A switch 3 point mutation in the alpha subunit of transducin yields a unique dominant-negative inhibitor.
Topics: Aluminum Compounds; Animals; Arginine; Catalysis; Cattle; Chromatography, High Pressure Liquid; Cyclic GMP; Dose-Response Relationship, Drug; Fluorides; Genes, Dominant; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Models, Biological; Models, Molecular; Mutation; Nucleotides; Point Mutation; Protein Conformation; Recombinant Fusion Proteins; Recombinant Proteins; Retina; Rhodopsin; Signal Transduction; Spectrometry, Fluorescence; Time Factors; Transducin; Trypsin | 2005 |
Gbetagamma inhibits Galpha GTPase-activating proteins by inhibition of Galpha-GTP binding during stimulation by receptor.
Topics: Aluminum Compounds; Animals; Bacterial Proteins; Binding Sites; Catalysis; Cell Line; Escherichia coli; Eye Proteins; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Fluorides; Green Fluorescent Proteins; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; GTP-Binding Protein Regulators; GTPase-Activating Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Inhibitory Concentration 50; Insecta; Kinetics; Luminescent Proteins; Mutation; Phosphoproteins; Protein Binding; RGS Proteins; Spectrometry, Fluorescence; Type C Phospholipases | 2006 |
Structure of a GDP:AlF4 complex of the SRP GTPases Ffh and FtsY, and identification of a peripheral nucleotide interaction site.
Topics: Aluminum Compounds; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Dimerization; Fluorides; Fluorometry; GTP Phosphohydrolases; Guanosine Diphosphate; Guanosine Triphosphate; Magnesium; Models, Molecular; Molecular Conformation; Protein Binding; Receptors, Cytoplasmic and Nuclear; RNA, Bacterial; Signal Recognition Particle; Thermus | 2006 |
TBC-domain GAPs for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism.
Topics: Aluminum Compounds; Animals; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Fluorides; GTPase-Activating Proteins; Guanosine Triphosphate; Hydrolysis; Models, Molecular; Mutation; Protein Structure, Tertiary; rab GTP-Binding Proteins; Saccharomyces cerevisiae Proteins; Static Electricity; Structure-Activity Relationship; Substrate Specificity | 2006 |
Endoplasmic reticulum-associated degradation of mutant CFTR requires a guanine nucleotide-sensitive step.
Topics: Adenosine Triphosphate; Aluminum Compounds; Animals; Cell Line; Cricetinae; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Fluorides; Guanosine Triphosphate; Humans; Mutation; Proteasome Endopeptidase Complex; Receptors, Antigen, T-Cell, alpha-beta; Sensitivity and Specificity | 2008 |
Visualization of the eEF2-80S ribosome transition-state complex by cryo-electron microscopy.
Topics: Aluminum Compounds; Cryoelectron Microscopy; Fluorides; Fungal Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Models, Molecular; Peptide Elongation Factor 2; Protein Structure, Tertiary; Ribosomes | 2008 |
The initiation of GTP hydrolysis by the G-domain of FeoB: insights from a transition-state complex structure.
Topics: Aluminum Compounds; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Biocatalysis; Cation Transport Proteins; Crystallography, X-Ray; Fluorides; GTP Phosphohydrolases; Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Models, Molecular; Molecular Sequence Data; Mutation; Potassium; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Streptococcus thermophilus; Substrate Specificity; Threonine; Water | 2011 |
Structural basis for conformational switching and GTP loading of the large G protein atlastin.
Topics: Aluminum Compounds; Chromatography, Gel; Crystallography; Dimerization; Endoplasmic Reticulum; Fluorescence Resonance Energy Transfer; Fluorides; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Hydrolysis; Kinetics; Membrane Proteins; Models, Molecular; Protein Conformation | 2013 |
EF-G Activation by Phosphate Analogs.
Topics: Aluminum Compounds; Boranes; Fluorides; GTP Phosphohydrolases; Guanosine Triphosphate; Hydrolysis; Peptide Elongation Factor G; Phosphates; Protein Biosynthesis; Ribosomes; RNA, Messenger; RNA, Transfer | 2016 |
Noncanonical Myo9b-RhoGAP Accelerates RhoA GTP Hydrolysis by a Dual-Arginine-Finger Mechanism.
Topics: Arginine; Catalysis; Catalytic Domain; Fluorides; GTPase-Activating Proteins; Guanosine Triphosphate; Humans; Hydrolysis; Magnesium Compounds; Myosins; Protein Binding; rho GTP-Binding Proteins; rhoA GTP-Binding Protein | 2016 |