fluorides has been researched along with guanosine diphosphate in 94 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 14 (14.89) | 18.7374 |
1990's | 50 (53.19) | 18.2507 |
2000's | 26 (27.66) | 29.6817 |
2010's | 3 (3.19) | 24.3611 |
2020's | 1 (1.06) | 2.80 |
Authors | Studies |
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Cassel, D; Eckstein, F; Levkovitz, H; Lowe, M; Selinger, Z | 1 |
Gruenert, DC; Kizer, N; Schwiebert, EM; Stanton, BA | 1 |
Biondi, C; Buzzi, M; Campi, AL; Cavallaro, R; Ferretti, ME; Pareschi, MC | 1 |
Brown, KO; Hepler, JR; Smrcka, AV; Sternweis, PC | 1 |
Cerione, RA; Phillips, WJ | 1 |
Andersson, T; Bengtsson, T; Särndahl, E; Stendahl, O | 1 |
Fennell, DF; Kurrus, JA; McIntyre, TM; Prescott, SM; Whatley, RE; Zimmerman, GA | 1 |
Teitelbaum, I | 1 |
Antonny, B; Bigay, J; Chabre, M | 1 |
Kirkwood, A; Lisman, JE; Weiner, D | 1 |
Carlier, MF; Didry, D; Pantaloni, D; Simon, C | 1 |
Carlier, MF; Combeau, C | 1 |
Bigay, J; Chabre, M; Deterre, P; Pfister, C | 2 |
Ramkumar, V; Stiles, GL | 1 |
Hasegawa-Sasaki, H; Lutz, F; Sasaki, T | 1 |
Beiderman, B; Bourne, HR; Masters, SB; Miller, RT; Sullivan, KA | 1 |
Aurbach, GD; Downs, RW; Reen, S; Singer, M; Spiegel, AM | 1 |
Bourne, HR; Farfel, Z; Johnson, GL; Kaslow, HR | 1 |
Kempner, E; Lad, PM; Nielsen, TB; Preston, MS; Rodbell, M; Schlegel, W | 1 |
Goldhammer, A; Wolff, J | 1 |
Birnbaumer, L; Iyengar, R | 1 |
Cerione, RA; Erickson, JW; Mittal, R | 1 |
Fujishiro, N; Imanaga, I; Inoue, M | 1 |
Bobkov, AA; Levitsky, DI | 1 |
Hicks, JL; Salter, MW | 1 |
Enomoto, K; Maeno, T | 1 |
Frangos, JA; Jo, H; Kuchan, MJ | 1 |
Birnbaumer, L; Codina, J | 1 |
Hamm, HE; Lambright, DG; Noel, JP; Sigler, PB; Sondek, J | 1 |
Makhlouf, GM; Murthy, KS | 1 |
Berghuis, AM; Coleman, DE; Gilman, AG; Lee, E; Linder, ME; Sprang, SR | 1 |
Inanobe, A; Katada, T; Kurachi, Y; Terzic, A; Tung, RT | 1 |
Alexandropoulos, K; Foster, DA; Jiang, H; Song, J | 1 |
Chabre, M; Chardin, P; Faurobert, E; Otto-Bruc, A | 1 |
Bosenberg, MW; Massagué, J; Pandiella, A | 1 |
Antonny, B; Bigay, J; Chabre, M; Higashijima, T; Sukumar, M | 1 |
Carter, LL; Redelmeier, TE; Schmid, SL; Woollenweber, LA | 1 |
Augustine, GJ; Doroshenko, PA; Hess, SD | 1 |
Carlier, MF; Melki, R | 1 |
Rupnik, M; Zorec, R | 1 |
Ahmadian, MR; Goody, RS; Mittal, R; Wittinghofer, A | 1 |
Andersson, T; Bokoch, GM; Boulay, F; Särndahl, E; Stendahl, O | 1 |
Parekh, AB | 1 |
Berman, DM; Gilman, AG; Kozasa, T | 1 |
Bourne, HR; Chi, P; Garcia, PD; Herzmark, P; Kingsley, C; Lichtarge, O; Onrust, R | 1 |
Delmas, P; Gola, M | 1 |
Berman, DM; Gilman, AG; Sprang, SR; Tesmer, JJ | 1 |
Ahmadian, MR; Kabsch, W; Lautwein, A; Scheffzek, K; Schmitz, F; Wiesmüller, L; Wittinghofer, A | 1 |
Díaz, JF; Engelborghs, Y; Sillen, A | 1 |
Andersson, T; Dimitrijevic, I; Eckerdal, J; Zheng, L | 1 |
Sprang, SR | 1 |
Bollag, G; Gilman, AG; Hart, MJ; Jiang, X; Kozasa, T; Singer, WD; Sternweis, PC; Sternweis, PM | 1 |
Bollag, G; Gilman, AG; Hart, MJ; Jiang, X; Kozasa, T; Roscoe, W; Singer, WD; Sternweis, PC | 1 |
Matalon, R; Warner, DR; Weinstein, LS; Weng, G; Yu, S | 1 |
Caplow, M; Shanks, J | 1 |
Zhang, B; Zheng, Y | 1 |
Eccleston, JF; Graham, DL; Lowe, PN | 1 |
Romanowski, R; Warner, DR; Weinstein, LS; Yu, S | 1 |
Warner, DR; Weinstein, LS | 1 |
Díaz, JF; Engelborghs, Y; Kuppens, S | 1 |
Geyer, M; Herrmann, C; Praefcke, GJ; Robert Kalbitzer, H; Schwemmle, M | 1 |
Coleman, DE; Sprang, SR | 1 |
Chung, CW; Eccleston, JF; Graham, DL; Lowe, PN | 1 |
Díaz, JF; Engelborghs, Y; Escalona, MM; Kuppens, S | 1 |
Fukamizu, A; Haga, T; Ishida, J; Kimura, S; Moroi, K; Nishiyama, M; Sekiya, S; Shibasaki, T; Usui, H; Zhou, J | 1 |
Hamm, HE; Skiba, NP; Thomas, TO | 1 |
Brown, FD; Donaldson, JG; Foroni, L; Hsu, VW; Jackson, TR; Miura, K; Nie, Z; Randazzo, PA; Sun, J | 1 |
Li, H; Wu, G; Yang, Z | 1 |
Brothers, GM; De Vries, L; Farquhar, MG; Fischer, T; Siderovski, DP; Strockbine, B; Tronchère, H | 1 |
Ahmadian, MR; Barbieri, JT; Buchwald, G; Pederson, KJ; Wittinghofer, A; Wolf, E; Würtele, M | 1 |
Quinton, PM; Reddy, MM; Sun, D | 1 |
Galán, JE; Stebbins, CE | 1 |
Behe, CI; De Vries, L; Gist Farquhar, M; Kimple, RJ; Morris, RA; Siderovski, DP; Tronchère, H | 1 |
Miller, HP; Panda, D; Wilson, L | 1 |
Aebi, U; Haener, M; Haller, O; Kochs, G | 1 |
Ashford, AE; Cole, L; Davies, D; Hyde, GJ | 1 |
Eccleston, JF; Gamblin, SJ; Graham, DL; Grime, GW; Lowe, PN; Marsh, M; Rittinger, K; Smerdon, SJ | 1 |
Brito, M; Guzmán, L; Hinrichs, MV; Olate, J; Romo, X; Soto, X | 1 |
Hamm, HE; Hubbell, WL; Medkova, M; Preininger, AM; Van Eps, N; Yu, NJ | 1 |
González, JM; Mingorance, J; Rivas, G; Tadros, M; Vélez, M; Vicente, M | 1 |
Cerione, RA; Pereira, R | 1 |
Jehl, M; Nayak, SK; Ross, EM; Tang, W; Tu, Y; Woodson, J | 1 |
Chardin, P; Franco, M; Klein, S; Luton, F | 1 |
Coon, JS; Focia, PJ; Freymann, DM; Gawronski-Salerno, J | 1 |
Arshavsky, VY; Blaesius, R; Fredericks, Z; Johnston, CA; Kuhlman, B; Lobanova, ES; Low, J; Ramer, JK; Shavkunov, AS; Siderovski, DP; Willard, FS | 1 |
Hwang, KY; Kim, EE; Ko, YG; Lee, WH; Nam, KH; Rhee, KH | 1 |
Cheng, HC; Gayler, KR; Gunawardana, D | 1 |
Frank, J; Gursky, R; Kjeldgaard, M; Nilsson, J; Nissen, P; Sengupta, J | 1 |
Gasper, R; Gotthardt, K; Meyer, S; Sirajuddin, M; Wittinghofer, A | 1 |
Acharya, S; Chappie, JS; Dyda, F; Leonard, M; Schmid, SL | 1 |
Ash, MR; Guss, JM; Jormakka, M; Maher, MJ | 1 |
Ataide, SF; Ban, N; Schmitz, N; Shan, SO; Shen, K; Voigts-Hoffmann, F | 1 |
Guo, X; Hu, J; Lou, Z; Qi, Y; Rao, Z; Yan, L; Yu, C; Zhao, J | 1 |
2 review(s) available for fluorides and guanosine diphosphate
Article | Year |
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Genetic analysis of hormone-sensitive adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cholera Toxin; Cyclic AMP; Fluorides; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hormones; Humans; Magnesium; Mice; Models, Biological; Receptors, Adrenergic, beta | 1980 |
It takes two to tango: regulation of G proteins by dimerization.
Topics: Aluminum Compounds; Animals; Binding Sites; Dimerization; Fluorides; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Models, Molecular; Plant Proteins; Protein Structure, Quaternary | 2009 |
92 other study(ies) available for fluorides and guanosine diphosphate
Article | Year |
---|---|
Guanosine 5'-O-(2-thiodiphosphate). An inhibitor of adenylate cyclase stimulation by guanine nucleotides and fluoride ions.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Erythrocyte Membrane; Fluorides; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Liver; Parotid Gland; Propranolol; Rats; Thionucleotides; Turkeys | 1979 |
GTP-binding proteins inhibit cAMP activation of chloride channels in cystic fibrosis airway epithelial cells.
Topics: Aluminum; Aluminum Compounds; Cell Line; Cell Line, Transformed; Cells, Cultured; Chloride Channels; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelium; Fluorides; Fluorine; Genotype; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Ion Channels; Membrane Potentials; Membrane Proteins; Mutation; Pertussis Toxin; Respiratory Physiological Phenomena; Respiratory System; Thionucleotides; Virulence Factors, Bordetella | 1992 |
Adenylate cyclase from Hirudo medicinalis segmental ganglia: modulation by physiological and non-physiological agents.
Topics: Adenylyl Cyclases; Animals; Fluorides; Ganglia; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Leeches; Serotonin; Thionucleotides | 1992 |
Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq.
Topics: Aluminum; Aluminum Compounds; Animals; Calcium; Cattle; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanosine Diphosphate; In Vitro Techniques; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Substrate Specificity | 1991 |
Labeling of the beta gamma subunit complex of transducin with an environmentally sensitive cysteine reagent. Use of fluorescence spectroscopy to monitor transducin subunit interactions.
Topics: Aluminum; Aluminum Compounds; Anilino Naphthalenesulfonates; Animals; Cattle; Cysteine; Fluorides; Fluorine; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Kinetics; Macromolecular Substances; Rhodopsin; Rod Cell Outer Segment; Spectrometry, Fluorescence; Sulfhydryl Reagents; Transducin | 1991 |
Involvement of GTP-binding proteins in actin polymerization in human neutrophils.
Topics: Actins; Aluminum; Aluminum Compounds; Aminoquinolines; Calcium; Cytosol; Fluorescent Dyes; Fluorides; Fluorine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Humans; In Vitro Techniques; Kinetics; Macromolecular Substances; Neutrophils; Thionucleotides; Type C Phospholipases | 1990 |
Synthesis of platelet-activating factor by endothelial cells. The role of G proteins.
Topics: Aluminum; Aluminum Compounds; Animals; Biological Transport, Active; Calcium; Cattle; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Fluorides; Fluorine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Humans; Kinetics; Neutrophils; Platelet Activating Factor; Sodium Fluoride; Thionucleotides | 1990 |
The epidermal growth factor receptor is coupled to a phospholipase A2-specific pertussis toxin-inhibitable guanine nucleotide-binding regulatory protein in cultured rat inner medullary collecting tubule cells.
Topics: Adenosine Diphosphate Ribose; Aluminum; Aluminum Compounds; Animals; Calcium; Cells, Cultured; Dinoprostone; Epidermal Growth Factor; ErbB Receptors; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Kidney Medulla; Kidney Tubules; Kidney Tubules, Collecting; Kinetics; Pertussis Toxin; Phosphatidylinositols; Phospholipases; Phospholipases A; Phospholipases A2; Rats; Tetradecanoylphorbol Acetate; Thionucleotides; Virulence Factors, Bordetella | 1990 |
A novel magnesium-dependent mechanism for the activation of transducin by fluoride.
Topics: Aluminum; Aluminum Compounds; Animals; Beryllium; Cattle; Enzyme Activation; Fluorides; Guanosine Diphosphate; Kinetics; Magnesium; Rod Cell Outer Segment; Spectrometry, Fluorescence; Transducin | 1990 |
An estimate of the number of G regulator proteins activated per excited rhodopsin in living Limulus ventral photoreceptors.
Topics: Animals; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Horseshoe Crabs; Light; Photoreceptor Cells; Retinal Pigments; Rhodopsin; Thionucleotides; Time Factors; Vision, Ocular | 1989 |
Mechanism of GTP hydrolysis in tubulin polymerization: characterization of the kinetic intermediate microtubule-GDP-Pi using phosphate analogues.
Topics: Animals; Beryllium; Brain; Fluorides; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Kinetics; Macromolecular Substances; Mathematics; Microtubules; Models, Theoretical; Phosphates; Structure-Activity Relationship; Swine; Tubulin | 1989 |
Characterization of the aluminum and beryllium fluoride species bound to F-actin and microtubules at the site of the gamma-phosphate of the nucleotide.
Topics: Actins; Adenosine Diphosphate; Aluminum; Aluminum Compounds; Animals; Beryllium; Fluorides; Guanine Nucleotides; Guanosine Diphosphate; Microtubules; Muscles; Rabbits | 1989 |
Fluoride complexes of aluminium or beryllium act on G-proteins as reversibly bound analogues of the gamma phosphate of GTP.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Aluminum; Aluminum Compounds; Animals; Beryllium; Cattle; Fluorides; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Photoreceptor Cells; Protein Binding; Rod Cell Outer Segment | 1987 |
The new positive inotrope sulmazole inhibits the function of guanine nucleotide regulatory proteins by affecting GTP turnover.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipose Tissue; Animals; Cardiotonic Agents; Cholera Toxin; Colforsin; Cyclic AMP; Fluorides; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Pertussis Toxin; Rats; Rats, Inbred Strains; Virulence Factors, Bordetella | 1988 |
Pathway of phospholipase C activation initiated with platelet-derived growth factor is different from that initiated with vasopressin and bombesin.
Topics: Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Bombesin; Calcium; Cell Membrane Permeability; Cells, Cultured; Chlorides; Enzyme Activation; Fluorides; Fluorine; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Platelet-Derived Growth Factor; Rats; Saponins; Sodium Fluoride; Thionucleotides; Type C Phospholipases; Vasopressins | 1988 |
A mutation that prevents GTP-dependent activation of the alpha chain of Gs.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Aluminum; Aluminum Compounds; Animals; Binding Sites; Cell Membrane; DNA; Fluorides; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Lymphoma; Magnesium; Mice; Mutation; Protein Conformation; Trypsin; Tumor Cells, Cultured | 1988 |
Fluoroaluminates activate transducin-GDP by mimicking the gamma-phosphate of GTP in its binding site.
Topics: Aluminum; Aluminum Compounds; Animals; Binding Sites; Cattle; Fluorides; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Light; Membrane Proteins; Phosphates; Photoreceptor Cells; Rod Cell Outer Segment; Sodium Fluoride; Thionucleotides; Transducin | 1985 |
Fluoride stimulation of adenylate cyclase is dependent on the guanine nucleotide regulatory protein.
Topics: Adenylyl Cyclases; Animals; Enzyme Activation; Erythrocyte Membrane; Erythrocytes; Fluorides; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Monophosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Membrane Proteins; Temperature; Turkeys | 1980 |
Structure of the turkey erythrocyte adenylate cyclase system.
Topics: Adenylyl Cyclases; Animals; Benzyl Alcohols; Erythrocytes; Fluorides; Guanosine Diphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Molecular Weight; Pindolol; Protein Binding; Receptors, Adrenergic, beta; Turkeys | 1981 |
Interactions of fluoride and guanine nucleotides with thyroid adenylate cyclase.
Topics: Adenylate Kinase; Adenylyl Imidodiphosphate; Animals; Cattle; Enzyme Activation; Fluorides; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Phosphotransferases; Sodium Fluoride; Thionucleotides; Thyroid Gland | 1982 |
Hysteretic activation of adenylyl cyclases. I. Effect of Mg ion on the rate of activation by guanine nucleotides and fluoride.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Fluorides; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Liver; Magnesium; Rats; Sodium Fluoride | 1981 |
Aluminum fluoride activation of bovine transducin induces two distinct conformational changes in the alpha subunit.
Topics: Aluminum Compounds; Animals; Cattle; Energy Transfer; Eosine Yellowish-(YS); Fluoresceins; Fluorescent Dyes; Fluorides; Guanosine Diphosphate; Kinetics; Macromolecular Substances; Protein Conformation; Spectrometry, Fluorescence; Transducin | 1994 |
Mg2+-dependent phosphatase as an inhibitory mediator of the nonselective cation current induced by aluminum fluoride in guinea-pig chromaffin cells.
Topics: Aluminum Compounds; Animals; Cations; Chromaffin System; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guinea Pigs; Ion Channels; Magnesium; Muscarine; Muscarinic Agonists; Patch-Clamp Techniques; Phosphoprotein Phosphatases; Protein Phosphatase 2C | 1995 |
Differential scanning calorimetric study of the complexes of myosin subfragment 1 with nucleoside diphosphates and vanadate or beryllium fluoride.
Topics: Adenosine Diphosphate; Beryllium; Calorimetry, Differential Scanning; Cytidine Diphosphate; Fluorides; Guanosine Diphosphate; Inosine Diphosphate; Myosin Subfragments; Nucleotides; Protein Conformation; Thermodynamics; Uridine Diphosphate; Vanadates | 1995 |
ATP causes release of intracellular Ca2+ via the phospholipase C beta/IP3 pathway in astrocytes from the dorsal spinal cord.
Topics: Adenosine Triphosphate; Aluminum Compounds; Animals; Astrocytes; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Cells, Cultured; Egtazic Acid; Estrenes; Fetus; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Heparin; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Isoenzymes; Patch-Clamp Techniques; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Spinal Cord; Terpenes; Thapsigargin; Thionucleotides; Time Factors; Type C Phospholipases | 1995 |
Modification of frequency augmentation-potentiation by GTP gamma S in the frog neuromuscular junction.
Topics: Action Potentials; Aluminum Compounds; Animals; Cell Line; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Neuromuscular Junction; Ranidae; Thionucleotides | 1995 |
Role of G proteins in shear stress-mediated nitric oxide production by endothelial cells.
Topics: Aluminum Compounds; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Fluorides; GTP-Binding Proteins; Guanosine Diphosphate; Humans; Nitric Oxide; Osmolar Concentration; Pertussis Toxin; Stress, Mechanical; Thionucleotides; Virulence Factors, Bordetella | 1994 |
Requirement for intramolecular domain interaction in activation of G protein alpha subunit by aluminum fluoride and GDP but not by GTP gamma S.
Topics: Aluminum Compounds; Amino Acid Sequence; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Molecular Sequence Data | 1994 |
GTPase mechanism of Gproteins from the 1.7-A crystal structure of transducin alpha-GDP-AIF-4.
Topics: Aluminum Compounds; Animals; Cattle; Computer Graphics; Crystallography, X-Ray; Fluorides; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Hydrolysis; Mutagenesis; Protein Conformation; Transducin; Water | 1994 |
Fluoride activates G protein-dependent and -independent pathways in dispersed intestinal smooth muscle cells.
Topics: Animals; Biological Transport; Calcium; Cell Membrane Permeability; Cells, Cultured; Diglycerides; Fluorides; GTP-Binding Proteins; Guanosine Diphosphate; Guinea Pigs; Inositol Phosphates; Intestines; Muscle Contraction; Muscle, Smooth; Protein Kinase C; Thionucleotides | 1994 |
Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis.
Topics: Aluminum Compounds; Arginine; Binding Sites; Catalysis; Computer Graphics; Crystallography, X-Ray; Fluorides; Glutamine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Helix-Loop-Helix Motifs; Hydrogen Bonding; Hydrolysis; Models, Molecular; Protein Conformation; Protein Structure, Secondary | 1994 |
G proteins activate ATP-sensitive K+ channels by antagonizing ATP-dependent gating.
Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Aluminum Compounds; Animals; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guinea Pigs; Inosine Diphosphate; Ion Channel Gating; Potassium Channels; Thionucleotides; Uridine Diphosphate | 1994 |
Evidence that v-Src-induced phospholipase D activity is mediated by a G protein.
Topics: 3T3 Cells; Adenine Nucleotides; Aluminum Compounds; Animals; Arachidonic Acid; Avian Sarcoma Viruses; Benzoquinones; Cell Line, Transformed; Cholera Toxin; Enzyme Induction; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Kinetics; Lactams, Macrocyclic; Mice; Mice, Inbred BALB C; Myristic Acid; Myristic Acids; Oncogene Protein pp60(v-src); Phosphatidylcholines; Phospholipase D; Protein-Tyrosine Kinases; Quinones; Rifabutin; Tetradecanoylphorbol Acetate; Thionucleotides; Virulence Factors, Bordetella | 1994 |
Tryptophan W207 in transducin T alpha is the fluorescence sensor of the G protein activation switch and is involved in the effector binding.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Aluminum Compounds; Amino Acid Sequence; Animals; Baculoviridae; DNA Mutational Analysis; Enzyme Activation; Fluorescence; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Models, Molecular; Molecular Sequence Data; Moths; Protein Conformation; Recombinant Proteins; Rod Cell Outer Segment; Sequence Homology, Amino Acid; Signal Transduction; Transducin; Tryptophan | 1993 |
Activated release of membrane-anchored TGF-alpha in the absence of cytosol.
Topics: Aluminum; Aluminum Compounds; Animals; Cell Membrane; Cell Membrane Permeability; CHO Cells; Cricetinae; Fluorides; Fluorine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Kinetics; Protein Kinase C; Protein Precursors; Protein Processing, Post-Translational; Rats; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thionucleotides; Transfection; Transforming Growth Factor alpha | 1993 |
The mechanism of aluminum-independent G-protein activation by fluoride and magnesium. 31P NMR spectroscopy and fluorescence kinetic studies.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adenylyl Cyclases; Aluminum; Animals; Cattle; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanosine Diphosphate; In Vitro Techniques; Kinetics; Magnesium; Magnetic Resonance Spectroscopy; Recombinant Proteins; Spectrometry, Fluorescence; Transducin; Tryptophan | 1993 |
Multiple GTP-binding proteins participate in clathrin-coated vesicle-mediated endocytosis.
Topics: Aluminum; Aluminum Compounds; Amino Acid Sequence; Coated Pits, Cell-Membrane; Endocytosis; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Humans; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Molecular Sequence Data; Peptides; Receptors, Transferrin; Thionucleotides; Tumor Cells, Cultured; Wasp Venoms | 1993 |
A functional role for GTP-binding proteins in synaptic vesicle cycling.
Topics: Aluminum; Aluminum Compounds; Animals; Calcium; Decapodiformes; Fluorides; Fluorine; Ganglia; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; In Vitro Techniques; Kinetics; Models, Neurological; Nerve Endings; Signal Transduction; Synaptic Vesicles; Thionucleotides; Time Factors | 1993 |
Thermodynamics of tubulin polymerization into zinc sheets: assembly is not regulated by GTP hydrolysis.
Topics: Aluminum; Aluminum Compounds; Animals; Beryllium; Brain; Colchicine; Fluorides; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Microscopy, Electron; Polymers; Rats; Subtilisins; Swine; Temperature; Thermodynamics; Tubulin; Zinc | 1993 |
Intracellular Cl- modulates Ca2+-induced exocytosis from rat melanotrophs through GTP-binding proteins.
Topics: Aluminum Compounds; Animals; Calcium; Cells, Cultured; Chlorides; Cytosol; Electrophysiology; Exocytosis; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Melanocytes; Patch-Clamp Techniques; Pertussis Toxin; Rats; Thionucleotides; Virulence Factors, Bordetella | 1995 |
Formation of a transition-state analog of the Ras GTPase reaction by Ras-GDP, tetrafluoroaluminate, and GTPase-activating proteins.
Topics: Aluminum Compounds; Amino Acid Sequence; Fluorides; GTP Phosphohydrolases; GTPase-Activating Proteins; Guanosine Diphosphate; Molecular Sequence Data; Mutagenesis; Neurofibromin 1; Proteins; ras GTPase-Activating Proteins; ras Proteins; Spectrometry, Fluorescence | 1996 |
Direct or C5a-induced activation of heterotrimeric Gi2 proteins in human neutrophils is associated with interaction between formyl peptide receptors and the cytoskeleton.
Topics: Aluminum Compounds; Complement C5a; Cytoskeleton; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Thionucleotides | 1996 |
Nonhydrolyzable analogues of GTP activate a new Na+ current in a rat mast cell line.
Topics: Animals; Biological Transport; Cell Membrane Permeability; Cell Polarity; Electric Conductivity; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hydrolysis; Mast Cells; Patch-Clamp Techniques; Rats; Second Messenger Systems; Sodium; Sodium Channels; Thionucleotides; Tumor Cells, Cultured | 1996 |
The GTPase-activating protein RGS4 stabilizes the transition state for nucleotide hydrolysis.
Topics: Aluminum Compounds; Animals; Fluorides; GTP Phosphohydrolases; GTP-Binding Proteins; GTPase-Activating Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Kinetics; Mammals; Proteins; Recombinant Proteins; RGS Proteins | 1996 |
Receptor and betagamma binding sites in the alpha subunit of the retinal G protein transducin.
Topics: Aluminum Compounds; Animals; Binding Sites; COS Cells; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Models, Molecular; Mutation; Phenotype; Protein Conformation; Retinaldehyde; Rhodopsin; Rod Cell Outer Segment; Transducin | 1997 |
Exotoxin-insensitive G proteins mediate synaptically evoked muscarinic sodium current in rabbit sympathetic neurones.
Topics: Animals; Cells, Cultured; Cholera Toxin; Electrophysiology; Exotoxins; Fluorides; Ganglia, Sympathetic; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Membrane Potentials; Muscarinic Agonists; Patch-Clamp Techniques; Pertussis Toxin; Rabbits; Receptors, Muscarinic; Sodium Channels; Sympathetic Nervous System; Synapses; Thionucleotides; Virulence Factors, Bordetella | 1997 |
Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysis.
Topics: Aluminum Compounds; Amino Acid Sequence; Animals; Binding Sites; Crystallography, X-Ray; Fluorides; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Magnesium; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Conformation; Proteins; Rats; RGS Proteins | 1997 |
The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants.
Topics: Aluminum Compounds; Amino Acid Sequence; Binding Sites; Catalysis; Cell Transformation, Neoplastic; Crystallography, X-Ray; Enzyme Activation; Fluorides; GTP Phosphohydrolases; GTP-Binding Proteins; GTPase-Activating Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Models, Molecular; Molecular Sequence Data; Mutation; Protein Conformation; Protein Structure, Secondary; Proteins; ras GTPase-Activating Proteins; ras Proteins; Signal Transduction | 1997 |
Equilibrium and kinetic study of the conformational transition toward the active state of p21Ha-ras, induced by the binding of BeF3- to the GDP-bound state, in the absence of GTPase-activating proteins.
Topics: Anions; Beryllium; Flow Injection Analysis; Fluorides; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Models, Chemical; Mutation; Phosphates; Protein Conformation; Proto-Oncogene Proteins p21(ras); Recombinant Proteins; Spectrometry, Fluorescence | 1997 |
Chemotactic peptide-induced activation of Ras in human neutrophils is associated with inhibition of p120-GAP activity.
Topics: Adaptor Proteins, Signal Transducing; Calcium; Fluorides; GRB2 Adaptor Protein; GTP-Binding Protein alpha Subunits, Gi-Go; GTPase-Activating Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neurofibromin 1; Neutrophils; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Precipitin Tests; Protein-Tyrosine Kinases; Proteins; ras GTPase-Activating Proteins; ras Proteins; Signal Transduction; Son of Sevenless Proteins; Type C Phospholipases; Virulence Factors, Bordetella | 1997 |
GAP into the breach.
Topics: Aluminum Compounds; Binding Sites; Catalysis; Crystallography, X-Ray; Fluorides; GTP Phosphohydrolases; GTP-Binding Proteins; GTPase-Activating Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Models, Molecular; Protein Conformation; Protein Structure, Secondary; Proteins; ras GTPase-Activating Proteins; ras Proteins; RGS Proteins | 1997 |
p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13.
Topics: Aluminum Compounds; Amino Acid Sequence; Animals; Fluorides; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, G12-G13; GTP-Binding Proteins; Guanine Nucleotide Exchange Factors; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Humans; Hydrolysis; Molecular Sequence Data; Proteins; Recombinant Fusion Proteins; Sequence Alignment; Signal Transduction | 1998 |
Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13.
Topics: Aluminum Compounds; Animals; COS Cells; Fluorides; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, G12-G13; GTP-Binding Proteins; Guanine Nucleotide Exchange Factors; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Proteins; Recombinant Fusion Proteins; Recombinant Proteins; Signal Transduction | 1998 |
A novel mutation in the switch 3 region of Gsalpha in a patient with Albright hereditary osteodystrophy impairs GDP binding and receptor activation.
Topics: Adenylyl Cyclases; Adult; Alanine; Aluminum Compounds; Amino Acid Sequence; Arginine; Base Sequence; Binding Sites; Cloning, Molecular; Erythrocyte Membrane; Escherichia coli; Exons; Female; Fibrous Dysplasia, Polyostotic; Fluorides; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Male; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Polymerase Chain Reaction; Protein Biosynthesis; Protein Structure, Secondary; Receptors, Cell Surface; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Tryptophan | 1998 |
Microtubule dynamic instability does not result from stabilization of microtubules by tubulin-GDP-Pi subunits.
Topics: Animals; Beryllium; Cattle; Fluorides; Guanosine Diphosphate; Microtubules; Models, Biological; Phosphates; Protein Binding; Protein Processing, Post-Translational; Tubulin | 1998 |
Negative regulation of Rho family GTPases Cdc42 and Rac2 by homodimer formation.
Topics: Aluminum Compounds; cdc42 GTP-Binding Protein, Saccharomyces cerevisiae; Cell Cycle Proteins; Dimerization; Fluorides; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Humans; ortho-Aminobenzoates; rac GTP-Binding Proteins; ras Proteins; rhoA GTP-Binding Protein; Sequence Alignment; Signal Transduction; Spectrometry, Fluorescence | 1998 |
The conserved arginine in rho-GTPase-activating protein is essential for efficient catalysis but not for complex formation with Rho.GDP and aluminum fluoride.
Topics: Alanine; Aluminum Compounds; Arginine; Catalysis; Conserved Sequence; Fluorides; GTP Phosphohydrolases; GTP-Binding Proteins; GTPase-Activating Proteins; Guanosine Diphosphate; Guanylyl Imidodiphosphate; Humans; Lysine; Macromolecular Substances; ortho-Aminobenzoates; Protein Binding; Rho Factor | 1999 |
Mutagenesis of the conserved residue Glu259 of Gsalpha demonstrates the importance of interactions between switches 2 and 3 for activation.
Topics: Aluminum Compounds; Animals; Base Sequence; Cattle; Conserved Sequence; DNA Primers; Fluorides; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Kinetics; Magnesium; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Recombinant Proteins | 1999 |
A mutation in the heterotrimeric stimulatory guanine nucleotide binding protein alpha-subunit with impaired receptor-mediated activation because of elevated GTPase activity.
Topics: Adenylyl Cyclases; Aluminum Compounds; Amino Acid Substitution; Animals; Arginine; Cattle; Cloning, Molecular; Escherichia coli; Fibrous Dysplasia, Polyostotic; Fluorides; Glutamine; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Isoproterenol; Kinetics; Macromolecular Substances; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Protein Structure, Secondary; Recombinant Proteins | 1999 |
Characterization of the hinges of the effector loop in the reaction pathway of the activation of ras-proteins. Kinetics of binding of beryllium trifluoride to V29G and I36G mutants of Ha-ras-p21.
Topics: Beryllium; Fluorides; Glycine; Guanosine Diphosphate; Humans; Isoleucine; Kinetics; Point Mutation; Protein Binding; Protein Conformation; Proto-Oncogene Proteins p21(ras); Thermodynamics; Valine | 1999 |
Nucleotide-binding characteristics of human guanylate-binding protein 1 (hGBP1) and identification of the third GTP-binding motif.
Topics: Aluminum Compounds; Binding Sites; Binding, Competitive; Calorimetry; DNA-Binding Proteins; Fluorides; Fluorometry; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Monophosphate; Guanosine Triphosphate; Humans; Kinetics; Magnetic Resonance Spectroscopy; Mutation; Recombinant Proteins; Thermodynamics | 1999 |
Reaction dynamics of G-protein catalyzed hydrolysis of GTP as viewed by X-ray crystallographic snapshots of Gi alpha 1.
Topics: Aluminum Compounds; Binding Sites; Crystallography, X-Ray; Fluorides; GTP Phosphohydrolases; GTP-Binding Proteins; GTPase-Activating Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Hydrogen Bonding; Models, Molecular; Protein Binding; Protein Conformation; Proteins; Signal Transduction | 1999 |
Magnesium fluoride-dependent binding of small G proteins to their GTPase-activating proteins.
Topics: Aluminum; Fluorides; GTPase-Activating Proteins; Guanosine Diphosphate; Kinetics; Magnesium Chloride; Magnesium Compounds; Magnetic Resonance Spectroscopy; Monomeric GTP-Binding Proteins; Neurofibromin 1; Protein Binding; Protein Conformation; Proteins; ras Proteins; rhoB GTP-Binding Protein; Sodium Fluoride; X-Ray Diffraction | 1999 |
Role of the switch II region in the conformational transition of activation of Ha-ras-p21.
Topics: Beryllium; Binding Sites; Catalytic Domain; Fluorides; Guanosine Diphosphate; Humans; In Vitro Techniques; Kinetics; Mutagenesis, Site-Directed; Protein Conformation; Proto-Oncogene Proteins p21(ras); Recombinant Proteins; Thermodynamics | 2000 |
RGS domain in the amino-terminus of G protein-coupled receptor kinase 2 inhibits Gq-mediated signaling.
Topics: Aluminum Compounds; Angiotensin II; beta-Adrenergic Receptor Kinases; Calcium; Cell Line; Cyclic AMP-Dependent Protein Kinases; Endothelin-1; Fluorides; Fura-2; GTP-Binding Protein Regulators; GTP-Binding Proteins; Guanosine Diphosphate; Humans; Plasmids; Signal Transduction; Transfection | 2000 |
G alpha t/G alpha i1 chimeras used to define structural basis of specific functions of G alpha t.
Topics: Aluminum Compounds; Amino Acid Substitution; Cloning, Molecular; Escherichia coli; Fluorides; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Kinetics; Models, Molecular; Polymerase Chain Reaction; Protein Conformation; Protein Structure, Secondary; Recombinant Fusion Proteins; Restriction Mapping; Transducin | 2000 |
ACAPs are arf6 GTPase-activating proteins that function in the cell periphery.
Topics: 3T3 Cells; Actins; ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Aluminum Compounds; Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Carrier Proteins; Cell Membrane; Cell Surface Extensions; Conserved Sequence; Cytoplasm; Cytoskeleton; Fluorides; GTPase-Activating Proteins; Guanosine Diphosphate; HeLa Cells; Humans; Mice; Molecular Sequence Data; Multigene Family; Phosphatidic Acids; Phosphatidylinositol 4,5-Diphosphate; Platelet-Derived Growth Factor; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity | 2000 |
Arabidopsis RopGAPs are a novel family of rho GTPase-activating proteins that require the Cdc42/Rac-interactive binding motif for rop-specific GTPase stimulation.
Topics: Aluminum Compounds; Arabidopsis; Binding Sites; Binding, Competitive; cdc42 GTP-Binding Protein; DNA, Complementary; Fluorides; GTPase-Activating Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Mutation; Protein Binding; Sequence Alignment; Sequence Analysis, DNA; Sequence Deletion | 2000 |
Activator of G protein signaling 3 is a guanine dissociation inhibitor for Galpha i subunits.
Topics: Aluminum Compounds; Amino Acid Motifs; Amino Acid Sequence; Animals; Cell Fractionation; Fluorides; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Guanine; Guanine Nucleotide Dissociation Inhibitors; Guanosine Diphosphate; Heterotrimeric GTP-Binding Proteins; Molecular Sequence Data; Rats; Tissue Distribution | 2000 |
How the Pseudomonas aeruginosa ExoS toxin downregulates Rac.
Topics: Aluminum Compounds; Amino Acid Sequence; Bacterial Toxins; Binding Sites; Catalysis; Crystallography, X-Ray; Down-Regulation; Fluorides; GTPase-Activating Proteins; Guanosine Diphosphate; Histidine Kinase; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Folding; Protein Kinases; Protein Structure, Secondary; Protein Structure, Tertiary; Pseudomonas aeruginosa; rac GTP-Binding Proteins; Sequence Alignment; Structure-Activity Relationship | 2001 |
Apical heterotrimeric g-proteins activate CFTR in the native sweat duct.
Topics: Adenosine Triphosphate; Adult; Aluminum Compounds; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Heterotrimeric GTP-Binding Proteins; Humans; Immunohistochemistry; In Vitro Techniques; Male; Mutation; Sodium Channels; Sodium-Potassium-Exchanging ATPase; Sweat Glands | 2001 |
Modulation of host signaling by a bacterial mimic: structure of the Salmonella effector SptP bound to Rac1.
Topics: Aluminum Compounds; Amino Acid Sequence; Amino Acid Substitution; Bacterial Proteins; Binding Sites; cdc42 GTP-Binding Protein; Crystallography, X-Ray; Dimerization; Evolution, Molecular; Fluorides; GTPase-Activating Proteins; Guanosine Diphosphate; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Mutation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Tyrosine Phosphatases; rac1 GTP-Binding Protein; Recombinant Fusion Proteins; Salmonella typhimurium; Sequence Alignment; Signal Transduction | 2000 |
RGS12 and RGS14 GoLoco motifs are G alpha(i) interaction sites with guanine nucleotide dissociation inhibitor Activity.
Topics: Aluminum Compounds; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Biosensing Techniques; Cloning, Molecular; Escherichia coli; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Heterotrimeric GTP-Binding Proteins; Kinetics; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligopeptides; Open Reading Frames; Rats; Recombinant Proteins; RGS Proteins; Signal Transduction; Surface Plasmon Resonance | 2001 |
Determination of the size and chemical nature of the stabilizing "cap" at microtubule ends using modulators of polymerization dynamics.
Topics: Aluminum Compounds; Animals; Beryllium; Binding Sites; Brain Chemistry; Cattle; Fluorides; Guanosine Diphosphate; Guanosine Triphosphate; Male; Microscopy, Video; Microtubules; Phosphates; Phosphorus Radioisotopes; Polymers; Sea Urchins; Spermatozoa; Thermodynamics; Tubulin | 2002 |
Self-assembly of human MxA GTPase into highly ordered dynamin-like oligomers.
Topics: Aluminum Compounds; Dimerization; Dynamins; Escherichia coli; Fluorides; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Microscopy, Electron; Myxovirus Resistance Proteins; Protein Binding; Protein Conformation; Proteins; Recombinant Proteins; Salts | 2002 |
Regulators of GTP-binding proteins cause morphological changes in the vacuole system of the filamentous fungus, Pisolithus tinctorius.
Topics: Aluminum Compounds; Basidiomycota; Brefeldin A; Cytoskeleton; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Hyphae; Protein Synthesis Inhibitors; Thionucleotides; Transport Vesicles; Vacuoles | 2002 |
MgF(3)(-) as a transition state analog of phosphoryl transfer.
Topics: Aluminum Compounds; Fluorides; Guanosine Diphosphate; Magnesium Compounds; Models, Molecular; Phosphorus; rho GTP-Binding Proteins; Spectrometry, X-Ray Emission | 2002 |
S111N mutation in the helical domain of human Gs(alpha) reduces its GDP/GTP exchange rate.
Topics: Adenylyl Cyclases; Aluminum Compounds; Amino Acid Substitution; Asparagine; Fluorides; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Humans; Models, Molecular; Point Mutation; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Cell Surface; Serine; Trypsin | 2002 |
The myristoylated amino terminus of Galpha(i)(1) plays a critical role in the structure and function of Galpha(i)(1) subunits in solution.
Topics: Aluminum Compounds; Cysteine; DNA Primers; Electron Spin Resonance Spectroscopy; Electrophoresis, Polyacrylamide Gel; Fluorescent Dyes; Fluorides; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Models, Molecular; Mutagenesis, Site-Directed; Myristic Acid; Protein Binding; Protein Conformation; Spin Labels; Structure-Activity Relationship; Sulfhydryl Compounds | 2003 |
Visualization of single Escherichia coli FtsZ filament dynamics with atomic force microscopy.
Topics: Adsorption; Aluminum Compounds; Aluminum Silicates; Chemical Phenomena; Chemistry, Physical; Escherichia coli; Escherichia coli Proteins; Fluorides; Guanosine Diphosphate; Guanosine Triphosphate; Hydrogen-Ion Concentration; Microscopy, Atomic Force; Polymers; Solutions | 2005 |
A switch 3 point mutation in the alpha subunit of transducin yields a unique dominant-negative inhibitor.
Topics: Aluminum Compounds; Animals; Arginine; Catalysis; Cattle; Chromatography, High Pressure Liquid; Cyclic GMP; Dose-Response Relationship, Drug; Fluorides; Genes, Dominant; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Models, Biological; Models, Molecular; Mutation; Nucleotides; Point Mutation; Protein Conformation; Recombinant Fusion Proteins; Recombinant Proteins; Retina; Rhodopsin; Signal Transduction; Spectrometry, Fluorescence; Time Factors; Transducin; Trypsin | 2005 |
Gbetagamma inhibits Galpha GTPase-activating proteins by inhibition of Galpha-GTP binding during stimulation by receptor.
Topics: Aluminum Compounds; Animals; Bacterial Proteins; Binding Sites; Catalysis; Cell Line; Escherichia coli; Eye Proteins; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Fluorides; Green Fluorescent Proteins; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; GTP-Binding Protein Regulators; GTPase-Activating Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Inhibitory Concentration 50; Insecta; Kinetics; Luminescent Proteins; Mutation; Phosphoproteins; Protein Binding; RGS Proteins; Spectrometry, Fluorescence; Type C Phospholipases | 2006 |
Role of the Arf6 GDP/GTP cycle and Arf6 GTPase-activating proteins in actin remodeling and intracellular transport.
Topics: Actins; ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Aluminum Compounds; Animals; Biological Transport; Cell Line; Cricetinae; Cytoskeleton; Fluorides; GTPase-Activating Proteins; Guanosine Diphosphate; HeLa Cells; Humans; Mutation; Phospholipids; Protein Binding; Recombinant Proteins | 2006 |
Structure of a GDP:AlF4 complex of the SRP GTPases Ffh and FtsY, and identification of a peripheral nucleotide interaction site.
Topics: Aluminum Compounds; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Dimerization; Fluorides; Fluorometry; GTP Phosphohydrolases; Guanosine Diphosphate; Guanosine Triphosphate; Magnesium; Models, Molecular; Molecular Conformation; Protein Binding; Receptors, Cytoplasmic and Nuclear; RNA, Bacterial; Signal Recognition Particle; Thermus | 2006 |
Minimal determinants for binding activated G alpha from the structure of a G alpha(i1)-peptide dimer.
Topics: Aluminum Compounds; Amino Acid Sequence; Amino Acid Substitution; Bacterial Proteins; Crystallography, X-Ray; Dimerization; Fluorides; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine Diphosphate; Humans; Luminescent Proteins; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Structure, Secondary; Recombinant Fusion Proteins; RGS Proteins; Structure-Activity Relationship | 2006 |
Expression, purification, and preliminary X-ray crystallographic analysis of the complex of G(alphai3)-RGS5 from human with GDP/Mg2+)/AlF4-.
Topics: Aluminum Compounds; Crystallography, X-Ray; Fluorides; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Guanosine Diphosphate; Humans; Magnesium; Molecular Sequence Data; Multiprotein Complexes; RGS Proteins; Second Messenger Systems | 2006 |
Identification of functional domains in Arabidopsis thaliana mRNA decapping enzyme (AtDcp2).
Topics: Amino Acid Motifs; Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Computational Biology; Endoribonucleases; Escherichia coli; Fluorides; Glutamic Acid; Guanosine Diphosphate; Histidine; Lysine; Molecular Sequence Data; Mutation; Phosphines; Protein Structure, Tertiary; Recombinant Fusion Proteins; RNA, Messenger; Sequence Deletion | 2008 |
Visualization of the eEF2-80S ribosome transition-state complex by cryo-electron microscopy.
Topics: Aluminum Compounds; Cryoelectron Microscopy; Fluorides; Fungal Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Models, Molecular; Peptide Elongation Factor 2; Protein Structure, Tertiary; Ribosomes | 2008 |
G domain dimerization controls dynamin's assembly-stimulated GTPase activity.
Topics: Aluminum Compounds; Amino Acid Sequence; Biocatalysis; Catalytic Domain; Conserved Sequence; Crystallography, X-Ray; Dynamin I; Enzyme Activation; Fluorides; GTP Phosphohydrolases; Guanosine Diphosphate; Humans; Hydrolysis; Models, Molecular; Protein Multimerization; Protein Structure, Quaternary; Protein Structure, Tertiary; Sodium | 2010 |
The initiation of GTP hydrolysis by the G-domain of FeoB: insights from a transition-state complex structure.
Topics: Aluminum Compounds; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Biocatalysis; Cation Transport Proteins; Crystallography, X-Ray; Fluorides; GTP Phosphohydrolases; Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Models, Molecular; Molecular Sequence Data; Mutation; Potassium; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Streptococcus thermophilus; Substrate Specificity; Threonine; Water | 2011 |
The structural basis of FtsY recruitment and GTPase activation by SRP RNA.
Topics: Aluminum Compounds; Bacterial Proteins; Base Sequence; Catalytic Domain; Escherichia coli; Escherichia coli Proteins; Fluorides; GTP Phosphohydrolase Activators; GTP Phosphohydrolases; Guanosine Diphosphate; Hydrolysis; Molecular Sequence Data; Receptors, Cytoplasmic and Nuclear; RNA; RNA, Bacterial; Sequence Analysis, DNA; Signal Recognition Particle | 2013 |
Structural insights into G domain dimerization and pathogenic mutation of OPA1.
Topics: Beryllium; Binding Sites; Cloning, Molecular; Crystallography, X-Ray; Escherichia coli; Fluorides; Gene Expression; Genetic Vectors; GTP Phosphohydrolases; Guanosine Diphosphate; Humans; Liposomes; Magnesium; Models, Molecular; Mutation; Optic Atrophy; Potassium; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Multimerization; Recombinant Proteins | 2020 |