fluorides has been researched along with guanosine 5'-o-(3-thiotriphosphate) in 153 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 26 (16.99) | 18.7374 |
1990's | 113 (73.86) | 18.2507 |
2000's | 14 (9.15) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Gruenert, DC; Kizer, N; Schwiebert, EM; Stanton, BA | 1 |
Buccione, R; Downs, SM; Eppig, JJ | 1 |
Ganfornina, MD; López-Barneo, J | 1 |
Biondi, C; Buzzi, M; Campi, AL; Cavallaro, R; Ferretti, ME; Pareschi, MC | 1 |
Elmslie, KS; Jones, SW; Kammermeier, PJ | 1 |
Caron, MG; Hausdorff, WP; Kurose, H; Lefkowitz, RJ; Linder, ME; Luttrell, DK; Parsons, SJ; Pitcher, JA | 1 |
Gallin, EK; McKinney, LC | 1 |
Alafuzoff, I; Cowburn, RF; Fowler, CJ; O'Neill, C; Ravid, R; Winblad, B | 1 |
Kreis, TE; Robinson, MS | 1 |
Kawase, T; Van Breemen, C | 1 |
Kahn, RA; Melançon, P; Taylor, TC | 1 |
Dees, C; Hekman, M; Münch, G; Palm, D | 1 |
Boland, R; Coso, O; De Boland, AR; Flawia, M | 1 |
Furuya, W; Grinstein, S | 1 |
Comerford, JG; Dawson, AP | 1 |
Ambudkar, IS; Baum, BJ; Horn, VJ | 1 |
Donaldson, JG; Kahn, RA; Klausner, RD; Lippincott-Schwartz, J | 1 |
Donaldson, JG; Klausner, RD; Lippincott-Schwartz, J | 1 |
Cerione, RA; Phillips, WJ | 1 |
Cahalan, MD; McCloskey, MA | 1 |
Andersson, T; Bengtsson, T; Särndahl, E; Stendahl, O | 1 |
Fennell, DF; Kurrus, JA; McIntyre, TM; Prescott, SM; Whatley, RE; Zimmerman, GA | 1 |
Berti-Mattera, L; Chang, CH; Douglas, J; Hopfer, U; Sims, C; Zhou, J | 1 |
Gerritsen, ME; Mannix, RJ | 1 |
Teitelbaum, I | 1 |
de Laat, SW; Lambrechts, AC; Moolenaar, WH; Remorie, R; Tertoolen, LG; Tilly, BC | 1 |
LaBelle, EF; Murray, BM | 1 |
Csongor, J; Fóris, G; Fülöp, T; Leövey, A; Varga, Z | 1 |
Kirkwood, A; Lisman, JE; Weiner, D | 1 |
Boyer, JL; Downes, CP; Evans, T; Harden, TK; Northup, JK; Waldo, GL | 1 |
Bar-Nachum, S; Minke, B; Rubinstein, CT; Selinger, Z | 1 |
Balch, WE; Beckers, CJ | 1 |
Kondo, K; Kozawa, O; Oiso, Y; Takatsuki, K | 1 |
Boulias, C; Moscarello, MA | 1 |
Cockcroft, S; Geny, B; Stutchfield, J | 1 |
Fein, A; Szuts, EZ; Wood, SF | 1 |
Gleason, ML; Glick, BS; Malhotra, V; Melançon, P; Orci, L; Rothman, JE; Serafini, T; Weidman, PJ | 1 |
Aussel, C; Fehlmann, M; Ferrua, B; Mary, D; Pelassy, C; Peyron, JF | 1 |
Casteels, R; De Smedt, H; Missiaen, L; Vrolix, M; Wuytack, F | 1 |
Manning, DR; Nakada, MT; Woolkalis, MJ | 1 |
Brandt, DR; Ross, EM | 1 |
Akard, LP; English, D; Gabig, TG; Schell, MJ | 1 |
Hasegawa-Sasaki, H; Lutz, F; Sasaki, T | 1 |
Greiner, C; Jakobs, KH | 1 |
Sternweis, PC | 1 |
Gierschik, P; Spiegel, AM | 1 |
Dudai, Y; Zvi, S | 1 |
Goldhammer, A; Wolff, J | 1 |
Gilman, AG; Northup, JK; Smigel, MD | 1 |
Gilman, AG; Northup, JK; Smigel, MD; Sternweis, PC | 1 |
Corson, DW; Fein, A; Walthall, WW | 1 |
Bokoch, GM; Gilman, AG; Katada, T; Northup, JK; Smigel, M; Ui, M | 1 |
Corson, DW; Fein, A | 1 |
Kaznacheyeva, EV; Kiselyov, KI; Kuryshev, YA; Mamin, AG; Mozhayeva, GN; Naumov, AP | 1 |
Amaral, J; Behar, J; Biancani, P; Chen, Q; Harnett, KM; Yu, P | 1 |
Aunis, D; Bader, MF; Vitale, N | 1 |
Freemont, PS; Newman, RH; Rozengurt, E; Seckl, MJ | 1 |
Mironneau, C; Neuilly, G; Pelet, C; Rakotoarisoa, L | 1 |
Gandy, S; Greengard, P; Xu, H | 1 |
Biondi, C; Buzzi, M; Cavallaro, R; Fabbri, E; Ferretti, ME; Vesce, G | 1 |
Ambudkar, IS; Baum, BJ; Roth, GS; Sawaki, K | 1 |
Bubis, M; Zisapel, N | 1 |
Fujishiro, N; Imanaga, I; Inoue, M | 1 |
Díaz, A; Domínguez, L; Fornés, MW; Mayorga, LS | 1 |
Copenhaver, PF; Horgan, AM; Lagrange, MT | 1 |
Fujita, A; Hata, F; Nakajima, H; Nishio, H; Takeuchi, T | 1 |
Brown, DA; Gibb, AJ; Marsh, SJ; Stansfeld, CE | 1 |
Narula, N; Stow, JL | 1 |
Hicks, JL; Salter, MW | 1 |
Berridge, MJ; Petersen, CC | 1 |
Enomoto, K; Maeno, T | 1 |
Imanaga, I; Inoue, M | 1 |
Khurana, ML; Pandey, KN | 1 |
Harding, G; Jacobs, AA; Klein, JB; McLeish, KR; Scherzer, JA | 1 |
Berón, W; Colombo, MI; Mayorga, LS; Stahl, PD | 1 |
Gilman, AG; Kleuss, C; Lee, E; Raw, AS; Sprang, SR | 1 |
Arkinstall, S; Chabert, C; Chollet, A; Edgerton, MD | 1 |
Birnbaumer, L; Codina, J | 1 |
Carmeliet, E; Ito, H; Vereecke, J | 1 |
Hamm, HE; Lambright, DG; Noel, JP; Sigler, PB; Sondek, J | 1 |
Dubyak, GR; Kusner, DJ | 1 |
Berghuis, AM; Coleman, DE; Gilman, AG; Lee, E; Linder, ME; Sprang, SR | 1 |
De Boer, AH; Korthout, HA; Prins, HB; Van der Hoeven, PC; Van der Molen, GW | 1 |
Ausiello, DA; de Almeida, JB; Doherty, J; Stow, JL | 1 |
Kessels, GC; Niessen, HW; Verhoeven, AJ | 1 |
Inanobe, A; Katada, T; Kurachi, Y; Terzic, A; Tung, RT | 1 |
Akhtar, RA; Choi, MW | 1 |
Alexandropoulos, K; Foster, DA; Jiang, H; Song, J | 1 |
Chabre, M; Chardin, P; Faurobert, E; Otto-Bruc, A | 1 |
Jungermann, K; Miura, H; Neuschäfer-Rube, F; Püschel, GP | 1 |
Boyett, MR; Honjo, H; Kirby, MS; Yu, XJ; Zang, WJ | 1 |
Jope, RS; Powers, R; Song, L | 1 |
Aebischer, CP; Jörg, A; Pasche, I | 1 |
Hayashi, J; Liu, P; Wen, M | 1 |
Mattera, R; McConnell, BK; Wilkins, PL; Xing, M | 1 |
Cannon, SD; Walsh, KB; Wilson, SP | 1 |
Bosenberg, MW; Massagué, J; Pandiella, A | 1 |
Hager, R; Rooney, TA; Stubbs, CD; Thomas, AP | 1 |
Andersson, T; Bokoch, GM; Särndahl, E; Stendahl, O | 1 |
Bleasdale, JE; Justen, JM; Nidy, EG; Sam, LM; Smith, RJ | 1 |
Gilman, AG; Hepler, JR; Kozasa, T; Rhee, SG; Simon, MI; Smrcka, AV; Sternweis, PC | 1 |
Carter, LL; Redelmeier, TE; Schmid, SL; Woollenweber, LA | 1 |
Diehl, AM; Levine, MA; Samy, S; Wand, GS; Wolfgang, D | 1 |
Augustine, GJ; Doroshenko, PA; Hess, SD | 1 |
Harden, TK; Maurice, DH; Morris, AJ; Nicholas, RA; Waldo, GL | 1 |
Rupnik, M; Zorec, R | 1 |
Lemon, SC; Long, KJ; Walsh, KB; Wilson, SP | 1 |
Baldassare, JJ; Henderson, P; Padfield, PJ; Panesar, N | 1 |
Andersson, T; Bokoch, GM; Boulay, F; Särndahl, E; Stendahl, O | 1 |
Parekh, AB | 1 |
Emans, N; Verkman, AS | 1 |
Hong, W; Lowe, SL; Wong, SH | 1 |
Boland, R; de Boland, AR; Morelli, S | 1 |
Berman, DM; Gilman, AG; Kozasa, T | 1 |
Maeda, S; Miwa, Y; Saeki, M; Saito, K; Yamaji, A | 1 |
Bourne, HR; Chi, P; Garcia, PD; Herzmark, P; Kingsley, C; Lichtarge, O; Onrust, R | 1 |
Anderson, TJ; Gleeson, PA; Griffiths, G; Matheson, F; Stow, JL; Toh, BH | 1 |
Delmas, P; Gola, M | 1 |
Andreoli, V; Buratta, S; Iorio, A; Mozzi, R | 1 |
Fujihara, H; Gong, MC; Somlyo, AP; Somlyo, AV; Walker, LA | 1 |
Cleves, AE; Clift-O'Grady, L; Kelly, RB | 1 |
Hammond, HK; Insel, PA; Ping, P | 1 |
Boron, WF; Davis, BA; Hogan, EM | 1 |
Danon, A; Rimon, G; Rosenstock, M | 1 |
Barritt, GJ; Fernando, KC; Gregory, RB | 1 |
Berger, HA; Travis, SM; Welsh, MJ | 1 |
Alpert, J; Colodzin, R; Koutsos, M; McHale, NL; Mooney, JJ; Samson, JA; Schildkraut, JJ | 1 |
Padfield, PJ; Panesar, N | 1 |
Bollag, G; Gilman, AG; Hart, MJ; Jiang, X; Kozasa, T; Singer, WD; Sternweis, PC; Sternweis, PM | 1 |
Bollag, G; Gilman, AG; Hart, MJ; Jiang, X; Kozasa, T; Roscoe, W; Singer, WD; Sternweis, PC | 1 |
Matalon, R; Warner, DR; Weinstein, LS; Weng, G; Yu, S | 1 |
Bau, MY; Bloom, GS; Conrad, PA; Fullerton, AT | 1 |
del Saz, EG; Kobayashi, T; Okada, T; Seguchi, H; Zinchuk, VS | 1 |
Jones, KA; Kai, T; Warner, DO | 1 |
Romanowski, R; Warner, DR; Weinstein, LS; Yu, S | 1 |
Brown, EJ; Chung, J; Dimitry, J; Frazier, WA; Gao, AG; Lindberg, FP; Linder, ME | 1 |
Warner, DR; Weinstein, LS | 1 |
Hidalgo, J; Martín, ME; Vega, FM; Velasco, A | 1 |
Fleming, N; Li, L | 1 |
Hamm, HE; Skiba, NP; Thomas, TO | 1 |
Tse, A; Tse, FW | 1 |
Quinton, PM; Reddy, MM; Sun, D | 1 |
Behe, CI; De Vries, L; Gist Farquhar, M; Kimple, RJ; Morris, RA; Siderovski, DP; Tronchère, H | 1 |
Cismowski, MJ; Draper, E; Metodiev, M; Stone, DE | 1 |
Ashford, AE; Cole, L; Davies, D; Hyde, GJ | 1 |
Brito, M; Guzmán, L; Hinrichs, MV; Olate, J; Romo, X; Soto, X | 1 |
Jones, KA; Perkins, WJ; Warner, DO; Yoshimura, H | 1 |
Hamm, HE; Hubbell, WL; Medkova, M; Preininger, AM; Van Eps, N; Yu, NJ | 1 |
Durieux, ME; Hahnenkamp, K; Herroeder, S; Hoenemann, CW; Hollmann, MW; Kurz, KS; Struemper, D | 1 |
Kimple, RJ; Siderovski, DP; Willard, FS | 1 |
Eto, M; Luo, S; Matthew, JD; Somlyo, AP; Somlyo, AV; Stevenson, AS | 1 |
Denson, DD; Eaton, DC; Li, J; Wang, X | 1 |
Cerione, RA; Pereira, R | 1 |
1 review(s) available for fluorides and guanosine 5'-o-(3-thiotriphosphate)
Article | Year |
---|---|
Mechanisms of guanine nucleotide-mediated regulation of adenylate cyclase activity.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Bacterial Toxins; Cell Membrane; Cyclic AMP; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hormones; Humans; Kinetics; Mice; Rabbits; Rats; Receptors, Cell Surface; Thionucleotides; Virulence Factors, Bordetella | 1984 |
1 trial(s) available for fluorides and guanosine 5'-o-(3-thiotriphosphate)
Article | Year |
---|---|
Signal transduction by platelet adenylate cyclase: alterations in depressed patients may reflect impairment in the coordinated integration of cellular signals (coincidence detection).
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adult; Aluminum Compounds; Blood Platelets; Depressive Disorder; Dinoprostone; Female; Fluorides; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Male; Prostaglandin D2; Psychiatric Status Rating Scales; Signal Transduction | 1998 |
151 other study(ies) available for fluorides and guanosine 5'-o-(3-thiotriphosphate)
Article | Year |
---|---|
GTP-binding proteins inhibit cAMP activation of chloride channels in cystic fibrosis airway epithelial cells.
Topics: Aluminum; Aluminum Compounds; Cell Line; Cell Line, Transformed; Cells, Cultured; Chloride Channels; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelium; Fluorides; Fluorine; Genotype; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Ion Channels; Membrane Potentials; Membrane Proteins; Mutation; Pertussis Toxin; Respiratory Physiological Phenomena; Respiratory System; Thionucleotides; Virulence Factors, Bordetella | 1992 |
Modulation of meiotic arrest in mouse oocytes by guanyl nucleotides and modifiers of G-proteins.
Topics: Adenylate Cyclase Toxin; Aluminum; Aluminum Compounds; Animals; Bucladesine; Cells, Cultured; Cholera Toxin; Female; Fluorides; Follicle Stimulating Hormone; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hypoxanthine; Hypoxanthines; Mice; Mice, Inbred C57BL; Microinjections; Oogenesis; Ovarian Follicle; Pertussis Toxin; Virulence Factors, Bordetella; Zona Pellucida | 1992 |
Potassium channel types in arterial chemoreceptor cells and their selective modulation by oxygen.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channels; Carotid Body; Chemoreceptor Cells; Electric Conductivity; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Oxygen; Potassium Channels; Rabbits; Sodium Channels; Time Factors | 1992 |
Adenylate cyclase from Hirudo medicinalis segmental ganglia: modulation by physiological and non-physiological agents.
Topics: Adenylyl Cyclases; Animals; Fluorides; Ganglia; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Leeches; Serotonin; Thionucleotides | 1992 |
Calcium current modulation in frog sympathetic neurones: L-current is relatively insensitive to neurotransmitters.
Topics: Aluminum; Aluminum Compounds; Animals; Calcium Channels; Dose-Response Relationship, Drug; Fluorides; Ganglia, Sympathetic; Gonadotropin-Releasing Hormone; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Neurotransmitter Agents; Nifedipine; Norepinephrine; omega-Conotoxin GVIA; Peptides, Cyclic; Rana catesbeiana | 1992 |
Tyrosine phosphorylation of G protein alpha subunits by pp60c-src.
Topics: Animals; Fluorides; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Conformation; Proto-Oncogene Proteins pp60(c-src); Signal Transduction; Structure-Activity Relationship; Tyrosine | 1992 |
G-protein activators induce a potassium conductance in murine macrophages.
Topics: 4-Aminopyridine; Aluminum; Aluminum Compounds; Animals; Cells, Cultured; Electric Conductivity; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Kinetics; Macrophages; Mice; Pertussis Toxin; Potassium; Potassium Channels; Quinidine; Virulence Factors, Bordetella | 1992 |
Adenylyl cyclase activity in postmortem human brain: evidence of altered G protein mediation in Alzheimer's disease.
Topics: Adenylyl Cyclases; Aged; Aged, 80 and over; Aging; Aluminum; Aluminum Compounds; Alzheimer Disease; Brain; Cadaver; Colforsin; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Reference Values; Time Factors | 1992 |
Recruitment of coat proteins onto Golgi membranes in intact and permeabilized cells: effects of brefeldin A and G protein activators.
Topics: Adaptor Protein Complex alpha Subunits; Adaptor Protein Complex gamma Subunits; Adaptor Proteins, Vesicular Transport; Aluminum; Aluminum Compounds; Blotting, Western; Brefeldin A; Cell Line; Coatomer Protein; Cyclopentanes; Fluorides; Fluorine; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Microscopy, Fluorescence; Microtubule-Associated Proteins; Proteins | 1992 |
Aluminum fluoride induces a reversible Ca2+ sensitization in alpha-toxin-permeabilized vascular smooth muscle.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aluminum; Aluminum Compounds; Animals; Bacterial Toxins; Calcium; Egtazic Acid; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hemolysin Proteins; In Vitro Techniques; Isoquinolines; Muscle, Smooth, Vascular; Piperazines; Rabbits; Vasoconstriction | 1992 |
Two distinct members of the ADP-ribosylation factor family of GTP-binding proteins regulate cell-free intra-Golgi transport.
Topics: ADP-Ribosylation Factor 1; ADP-Ribosylation Factors; Aluminum; Aluminum Compounds; Biological Transport; Brefeldin A; Cell-Free System; Cyclopentanes; Fluorides; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Viral Proteins | 1992 |
Multisite contacts involved in coupling of the beta-adrenergic receptor with the stimulatory guanine-nucleotide-binding regulatory protein. Structural and functional studies by beta-receptor-site-specific synthetic peptides.
Topics: Aluminum; Aluminum Compounds; Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Dihydroalprenolol; Erythrocyte Membrane; Fluorides; Fluorine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Models, Molecular; Molecular Sequence Data; Oligopeptides; Peptides; Protein Conformation; Receptors, Adrenergic, beta; Turkeys | 1991 |
A guanine nucleotide-binding protein mediates 1,25-dihydroxy-vitamin D-3-dependent rapid stimulation of Ca2+ uptake in skeletal muscle.
Topics: Adenylate Cyclase Toxin; Aluminum; Animals; Biological Transport; Calcitriol; Calcium; Calcium Channels; Chickens; Cholera Toxin; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Male; Muscles; Nifedipine; Pertussis Toxin; Sarcolemma; Signal Transduction; Time Factors; Virulence Factors, Bordetella | 1991 |
Tyrosine phosphorylation and oxygen consumption induced by G proteins in neutrophils.
Topics: Adenine Nucleotides; Alkaloids; Aluminum; Aluminum Compounds; Fluorides; Fluorine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; In Vitro Techniques; Kinetics; Neutrophils; Oxygen Consumption; Pertussis Toxin; Phosphorylation; Phosphotyrosine; Protein Kinase C; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine; Virulence Factors, Bordetella | 1991 |
Fluoroaluminate treatment of rat liver microsomes inhibits GTP-dependent vesicle fusion.
Topics: Aluminum; Aluminum Compounds; Animals; Calcium; Fluorides; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Membrane Fusion; Microsomes, Liver; Polyethylene Glycols; Rats | 1991 |
High affinity quinuclidinyl benzilate binding to rat parotid membranes requires muscarinic receptor. G protein interactions.
Topics: Aluminum; Aluminum Compounds; Animals; Cell Membrane; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Magnesium; Male; Parotid Gland; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Sodium Fluoride | 1991 |
Binding of ARF and beta-COP to Golgi membranes: possible regulation by a trimeric G protein.
Topics: ADP-Ribosylation Factors; Aluminum; Aluminum Compounds; Animals; Biological Transport; Brefeldin A; CHO Cells; Coatomer Protein; Cricetinae; Cyclopentanes; Endoplasmic Reticulum; Fluorides; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Intracellular Membranes; Microtubule-Associated Proteins | 1991 |
Guanine nucleotides modulate the effects of brefeldin A in semipermeable cells: regulation of the association of a 110-kD peripheral membrane protein with the Golgi apparatus.
Topics: Adenosine Triphosphate; Aluminum; Aluminum Compounds; Animals; Brefeldin A; Cell Membrane Permeability; Cells, Cultured; Cyclopentanes; Cytosol; Fluorides; Fluorine; Golgi Apparatus; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Membrane Proteins; Molecular Weight | 1991 |
Labeling of the beta gamma subunit complex of transducin with an environmentally sensitive cysteine reagent. Use of fluorescence spectroscopy to monitor transducin subunit interactions.
Topics: Aluminum; Aluminum Compounds; Anilino Naphthalenesulfonates; Animals; Cattle; Cysteine; Fluorides; Fluorine; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Kinetics; Macromolecular Substances; Rhodopsin; Rod Cell Outer Segment; Spectrometry, Fluorescence; Sulfhydryl Reagents; Transducin | 1991 |
G protein control of potassium channel activity in a mast cell line.
Topics: Aluminum; Aluminum Compounds; Animals; Cell Line; Fluorides; Fluorine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Leukemia, Basophilic, Acute; Mast Cells; Neural Conduction; Potassium Channels; Rats; Thionucleotides | 1990 |
Involvement of GTP-binding proteins in actin polymerization in human neutrophils.
Topics: Actins; Aluminum; Aluminum Compounds; Aminoquinolines; Calcium; Cytosol; Fluorescent Dyes; Fluorides; Fluorine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Humans; In Vitro Techniques; Kinetics; Macromolecular Substances; Neutrophils; Thionucleotides; Type C Phospholipases | 1990 |
Synthesis of platelet-activating factor by endothelial cells. The role of G proteins.
Topics: Aluminum; Aluminum Compounds; Animals; Biological Transport, Active; Calcium; Cattle; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Fluorides; Fluorine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Humans; Kinetics; Neutrophils; Platelet Activating Factor; Sodium Fluoride; Thionucleotides | 1990 |
Proximal tubular epithelial cells possess a novel 42-kilodalton guanine nucleotide-binding regulatory protein.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Aluminum; Aluminum Compounds; Animals; Cell Membrane; Cholera Toxin; Colforsin; Epithelium; Fluorides; Fluorine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kidney Tubules, Proximal; Kinetics; Male; Microvilli; Molecular Weight; NAD; Parathyroid Hormone; Pertussis Toxin; Rabbits; Virulence Factors, Bordetella | 1990 |
G-proteins and phospholipase activation in endothelial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Triphosphate; Aluminum; Aluminum Compounds; Animals; Cells, Cultured; Dinoprostone; Endothelium, Vascular; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Pertussis Toxin; Phosphatidylinositols; Phospholipases A; Phospholipases A2; Rabbits; Virulence Factors, Bordetella | 1990 |
The epidermal growth factor receptor is coupled to a phospholipase A2-specific pertussis toxin-inhibitable guanine nucleotide-binding regulatory protein in cultured rat inner medullary collecting tubule cells.
Topics: Adenosine Diphosphate Ribose; Aluminum; Aluminum Compounds; Animals; Calcium; Cells, Cultured; Dinoprostone; Epidermal Growth Factor; ErbB Receptors; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Kidney Medulla; Kidney Tubules; Kidney Tubules, Collecting; Kinetics; Pertussis Toxin; Phosphatidylinositols; Phospholipases; Phospholipases A; Phospholipases A2; Rats; Tetradecanoylphorbol Acetate; Thionucleotides; Virulence Factors, Bordetella | 1990 |
Histamine-H1-receptor-mediated phosphoinositide hydrolysis, Ca2+ signalling and membrane-potential oscillations in human HeLa carcinoma cells.
Topics: Aluminum; Aluminum Compounds; Calcium; Chromatography, High Pressure Liquid; Diglycerides; Enzyme Activation; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; HeLa Cells; Histamine; Humans; Hydrolysis; Kinetics; Membrane Potentials; Periodicity; Phosphatidylinositols; Potassium Channels; Receptors, Histamine H1; Signal Transduction; Thionucleotides; Type C Phospholipases | 1990 |
G protein control of inositol lipids in intact vascular smooth muscle.
Topics: Aluminum; Aluminum Compounds; Animals; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Inositol Phosphates; Muscle, Smooth, Vascular; Norepinephrine; Pertussis Toxin; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Rats; Thionucleotides; Virulence Factors, Bordetella | 1990 |
Age related impairment in phosphatidylinositol breakdown of polymorphonuclear granulocytes.
Topics: Adult; Aged; Aging; Aluminum; Aluminum Compounds; Chloroquine; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; N-Formylmethionine Leucyl-Phenylalanine; Neomycin; Neutrophils; Phosphatidylinositols; Thionucleotides; Virulence Factors, Bordetella | 1989 |
An estimate of the number of G regulator proteins activated per excited rhodopsin in living Limulus ventral photoreceptors.
Topics: Animals; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Horseshoe Crabs; Light; Photoreceptor Cells; Retinal Pigments; Rhodopsin; Thionucleotides; Time Factors; Vision, Ocular | 1989 |
Modification of AlF-4- and receptor-stimulated phospholipase C activity by G-protein beta gamma subunits.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Aluminum; Aluminum Compounds; Animals; Brain; Cattle; Colforsin; Enzyme Activation; Erythrocyte Membrane; Female; Fluorides; Fluorine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Kinetics; Macromolecular Substances; Placenta; Pregnancy; Receptors, Purinergic; Thionucleotides; Turkeys; Type C Phospholipases | 1989 |
Chemically induced retinal degeneration in the rdgB (retinal degeneration B) mutant of Drosophila.
Topics: Animals; Darkness; Drosophila melanogaster; Electrophysiology; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Mutation; Nerve Degeneration; Retina | 1989 |
Calcium and GTP: essential components in vesicular trafficking between the endoplasmic reticulum and Golgi apparatus.
Topics: Aluminum; Aluminum Compounds; Animals; Biological Transport; Calcium; Cell Line; Cytosol; Endoplasmic Reticulum; Fluorides; Golgi Apparatus; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hydrolysis; Kinetics; Membrane Glycoproteins; Thionucleotides; Vesicular stomatitis Indiana virus; Viral Envelope Proteins | 1989 |
Ca2+ influx stimulated by vasopressin is mediated by phosphoinositide hydrolysis in rat smooth muscle cells.
Topics: Animals; Arginine Vasopressin; Calcium; Cell Membrane; Cyclic AMP; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Inositol Phosphates; Muscle, Smooth, Vascular; Neomycin; Pertussis Toxin; Phosphatidylinositols; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Receptors, Vasopressin; Sugar Phosphates; Thionucleotides; Virulence Factors, Bordetella | 1989 |
Guanine nucleotides stimulate hydrolysis of phosphatidyl inositol bis phosphate in human myelin membranes.
Topics: Adenosine Diphosphate Ribose; Aluminum; Aluminum Compounds; Cell Membrane; Fluorides; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Hydrolysis; Myelin Proteins; Myelin Sheath; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phosphoric Diester Hydrolases; Thionucleotides; Tritium | 1989 |
Phorbol ester inhibits polyphosphoinositide phosphodiesterase activity stimulated by either Ca2+, fluoride or GTP analogue in HL60 membranes and in permeabilized HL60 cells.
Topics: Calcium; Cell Membrane; Cell Membrane Permeability; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Protein Kinase C; Tetradecanoylphorbol Acetate; Thionucleotides; Tumor Cells, Cultured | 1989 |
Inositol trisphosphate production in squid photoreceptors. Activation by light, aluminum fluoride, and guanine nucleotides.
Topics: Aluminum; Aluminum Compounds; Animals; Decapodiformes; Fluorides; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Light; Photoreceptor Cells; Sugar Phosphates; Thionucleotides | 1989 |
Involvement of GTP-binding "G" proteins in transport through the Golgi stack.
Topics: Aluminum; Aluminum Compounds; Animals; Biological Transport; Cell Line; Cell-Free System; Fluorides; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Intracellular Membranes; Membrane Glycoproteins; Microscopy, Electron; Thionucleotides; Vesicular stomatitis Indiana virus; Viral Envelope Proteins; Viral Matrix Proteins | 1987 |
Inhibition and activation of interleukin 2 synthesis by direct modification of guanosine triphosphate-binding proteins.
Topics: Antigens, Differentiation, T-Lymphocyte; Calcimycin; CD3 Complex; Cell Line; Cholera Toxin; Cyclic AMP; Diglycerides; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Inositol Phosphates; Interleukin-2; Lymphocyte Activation; Pertussis Toxin; Phytohemagglutinins; T-Lymphocytes; Thionucleotides; Virulence Factors, Bordetella | 1988 |
AlF4- reversibly inhibits 'P'-type cation-transport ATPases, possibly by interacting with the phosphate-binding site of the ATPase.
Topics: Adenosine Triphosphatases; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Beryllium; Binding Sites; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Cell Membrane; Chlorides; Deferoxamine; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoenzymes; Magnesium; Magnesium Chloride; Nitrophenols; Organophosphorus Compounds; Phosphates; Sodium Fluoride; Sodium-Potassium-Exchanging ATPase; Swine; Thionucleotides | 1988 |
Alterations in components of adenylate cyclase associated with transformation of chicken embryo fibroblasts by Rous sarcoma virus.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Chick Embryo; Cholera Toxin; Colforsin; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Pertussis Toxin; Thionucleotides; Virulence Factors, Bordetella | 1986 |
Effect of Al3+ plus F- on the catecholamine-stimulated GTPase activity of purified and reconstituted Gs.
Topics: Aluminum; Animals; Catecholamines; Fluorides; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Liver; Phosphoric Monoester Hydrolases; Phosphorus Radioisotopes; Rabbits; Thionucleotides | 1986 |
Regulation of neutrophil NADPH oxidase activation in a cell-free system by guanine nucleotides and fluoride. Evidence for participation of a pertussis and cholera toxin-insensitive G protein.
Topics: Cell-Free System; Cholera Toxin; Chromatography, Gel; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Magnesium; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Pertussis Toxin; Receptors, Formyl Peptide; Receptors, Immunologic; Superoxides; Thionucleotides; Time Factors; Virulence Factors, Bordetella | 1987 |
Pathway of phospholipase C activation initiated with platelet-derived growth factor is different from that initiated with vasopressin and bombesin.
Topics: Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Bombesin; Calcium; Cell Membrane Permeability; Cells, Cultured; Chlorides; Enzyme Activation; Fluorides; Fluorine; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Platelet-Derived Growth Factor; Rats; Saponins; Sodium Fluoride; Thionucleotides; Type C Phospholipases; Vasopressins | 1988 |
Guanine nucleotide-independent inhibition of adenylate cyclase by a stimulatory hormone.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Alprostadil; Cell Membrane; Colforsin; Ethylmaleimide; Fluorides; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Thionucleotides; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1988 |
The purified alpha subunits of Go and Gi from bovine brain require beta gamma for association with phospholipid vesicles.
Topics: Aluminum; Animals; Brain Chemistry; Cattle; Centrifugation, Density Gradient; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Macromolecular Substances; Magnesium; Phospholipids; Thionucleotides | 1986 |
Chymotrypsin selectively decreases forskolin stimulation of adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Chymotrypsin; Colforsin; Erythrocyte Membrane; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Kinetics; Thionucleotides; Turkeys | 1985 |
Multiple defects in the activity of adenylate cyclase from the Drosophila memory mutant rutabaga.
Topics: Abdomen; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Calcium; Colforsin; Diterpenes; Drosophila melanogaster; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Head; Memory; Mutation; Octopamine; Thionucleotides; Thorax | 1985 |
Interactions of fluoride and guanine nucleotides with thyroid adenylate cyclase.
Topics: Adenylate Kinase; Adenylyl Imidodiphosphate; Animals; Cattle; Enzyme Activation; Fluorides; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Phosphotransferases; Sodium Fluoride; Thionucleotides; Thyroid Gland | 1982 |
Characteristics of the guanine nucleotide-binding regulatory component of adenylate cyclase.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Blood Proteins; Cell Membrane; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Mathematics; Receptors, Cell Surface; Thionucleotides | 1982 |
The subunits of the stimulatory regulatory component of adenylate cyclase. Resolution of the activated 45,000-dalton (alpha) subunit.
Topics: Adenylyl Cyclases; Aluminum; Animals; Chromatography, Gel; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Macromolecular Substances; Magnesium; Molecular Weight; Rabbits; Receptors, Cell Surface; Thionucleotides | 1983 |
Chemical excitation of Limulus photoreceptors. II. Vanadate, GTP-gamma-S, and fluoride prolong excitation evoked by dim flashes of light.
Topics: Animals; Evoked Potentials, Visual; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Horseshoe Crabs; Models, Biological; Phosphoric Monoester Hydrolases; Photic Stimulation; Photoreceptor Cells; Stimulation, Chemical; Thionucleotides; Vanadates; Vanadium | 1983 |
Excitation of Limulus photoreceptors by vanadate and by a hydrolysis-resistant analog of guanosine triphosphate.
Topics: Action Potentials; Adenylyl Cyclases; Animals; Carrier Proteins; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Horseshoe Crabs; Photoreceptor Cells; Thionucleotides; Vanadates; Vanadium | 1981 |
ATP-operated calcium-permeable channels activated via a guanine nucleotide-dependent mechanism in rat macrophages.
Topics: Adenosine Triphosphate; Animals; Calcium Channels; Cations; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Ion Channels; Macrophages; Male; Rats; Rats, Wistar | 1995 |
Direct G protein activation reverses impaired CCK signaling in human gallbladders with cholesterol stones.
Topics: Aluminum Compounds; Calmodulin; Cholecystokinin; Cholelithiasis; Cholesterol; Diglycerides; Dose-Response Relationship, Drug; Female; Fluorides; Gallbladder; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inositol 1,4,5-Trisphosphate; Male; Middle Aged; Muscle Contraction; Signal Transduction; Sincalide | 1995 |
Distinct heterotrimeric GTP-binding-proteins act in series to control the exocytotic machinery in chromaffin cells.
Topics: Adenosine Triphosphate; Aluminum Compounds; Amino Acid Sequence; Animals; Calcium; Cattle; Chromaffin System; Exocytosis; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Molecular Sequence Data; Norepinephrine; Oligopeptides; Peptides; Protein Conformation; Pyrrolidonecarboxylic Acid; Substance P; Wasp Venoms | 1994 |
Substance P-related antagonists inhibit vasopressin and bombesin but not 5'-3-O-(thio)triphosphate-stimulated inositol phosphate production in Swiss 3T3 cells.
Topics: 3T3 Cells; Aluminum Compounds; Amino Acid Sequence; Animals; Bombesin; Cell Line, Transformed; Dose-Response Relationship, Drug; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Inositol Phosphates; Liver; Mice; Molecular Sequence Data; Peptide Fragments; Rats; Substance P; Vasopressins | 1995 |
Angiotensin II receptor subtypes and contractile responses in portal vein smooth muscle.
Topics: Angiotensin II; Animals; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Horses; Ligands; Male; Muscle Contraction; Muscle, Smooth, Vascular; Portal Vein; Protease Inhibitors; Rats; Rats, Wistar; Receptors, Angiotensin | 1995 |
Regulated formation of Golgi secretory vesicles containing Alzheimer beta-amyloid precursor protein.
Topics: Aluminum Compounds; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Biological Transport, Active; Cell-Free System; Enzyme Activation; Fluorides; Golgi Apparatus; Guanosine 5'-O-(3-Thiotriphosphate); Humans; PC12 Cells; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats | 1995 |
Olfactory transduction mechanisms in sheep.
Topics: Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Epithelium; Ethylamines; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Inositol Phosphates; Kinetics; Odorants; Olfactory Mucosa; Sheep; Signal Transduction; Smell | 1995 |
Decreased m3-muscarinic and alpha 1-adrenergic receptor stimulation of PIP2 hydrolysis in parotid gland membranes from aged rats: defect in activation of G alpha q/11.
Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Aging; Aluminum Compounds; Animals; Carbachol; Dose-Response Relationship, Drug; Epinephrine; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hydrolysis; Isoenzymes; Membranes; Muscarinic Agonists; Parotid Gland; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phospholipase C beta; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Adrenergic, alpha-1; Receptors, Muscarinic; Receptors, Neurotransmitter; Signal Transduction; Type C Phospholipases | 1995 |
Facilitation and inhibition of G-protein regulated protein secretion by melatonin.
Topics: Aluminum Compounds; Animals; Cholera Toxin; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Melatonin; Mice; Neoplasm Proteins; Tumor Cells, Cultured | 1995 |
Mg2+-dependent phosphatase as an inhibitory mediator of the nonselective cation current induced by aluminum fluoride in guinea-pig chromaffin cells.
Topics: Aluminum Compounds; Animals; Cations; Chromaffin System; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guinea Pigs; Ion Channels; Magnesium; Muscarine; Muscarinic Agonists; Patch-Clamp Techniques; Phosphoprotein Phosphatases; Protein Phosphatase 2C | 1995 |
Reagents that activate GTP-binding proteins trigger the acrosome reaction in human spermatozoa.
Topics: Acrosome; Aluminum Compounds; Amino Acid Sequence; Calcimycin; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Intercellular Signaling Peptides and Proteins; Male; Molecular Sequence Data; Peptides; Reference Values; Spermatozoa; Wasp Venoms | 1995 |
Developmental expression of G proteins in a migratory population of embryonic neurons.
Topics: Aluminum Compounds; Animals; Cell Differentiation; Cell Movement; Cells, Cultured; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Immunoblotting; Immunohistochemistry; Intestines; Moths; Neurons; Type C Phospholipases | 1994 |
Involvement of heterotrimeric GTP-binding protein and rho protein, but not protein kinase C, in agonist-induced Ca2+ sensitization of skinned muscle of guinea pig vas deferens.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Aluminum Compounds; Animals; Botulinum Toxins; Calcium; Escin; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Peptides; Phorbol 12,13-Dibutyrate; Protein Kinase C; rho GTP-Binding Proteins; Vas Deferens | 1995 |
Identification of M-channels in outside-out patches excised from sympathetic ganglion cells.
Topics: Aluminum; Aluminum Compounds; Animals; Barium; Electric Conductivity; Electrophysiology; Fluorides; Fluorine; Ganglia, Sympathetic; Guanosine 5'-O-(3-Thiotriphosphate); Ion Channel Gating; Ion Channels; Kinetics; Reaction Time | 1993 |
Distinct coated vesicles labeled for p200 bud from trans-Golgi network membranes.
Topics: Aluminum Compounds; Animals; Brefeldin A; Cell Line; Coated Pits, Cell-Membrane; Coatomer Protein; Cyclopentanes; Cytosol; Fluorescent Antibody Technique; Fluorides; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Insecta; Kidney; Liver; Membrane Proteins; Microscopy, Immunoelectron; Microtubule-Associated Proteins; Phosphoproteins; Protein Binding; Protein Synthesis Inhibitors; Rats | 1995 |
ATP causes release of intracellular Ca2+ via the phospholipase C beta/IP3 pathway in astrocytes from the dorsal spinal cord.
Topics: Adenosine Triphosphate; Aluminum Compounds; Animals; Astrocytes; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Cells, Cultured; Egtazic Acid; Estrenes; Fetus; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Heparin; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Isoenzymes; Patch-Clamp Techniques; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Spinal Cord; Terpenes; Thapsigargin; Thionucleotides; Time Factors; Type C Phospholipases | 1995 |
G-protein regulation of capacitative calcium entry may be mediated by protein kinases A and C in Xenopus oocytes.
Topics: Adenylyl Cyclases; Aluminum Compounds; Animals; Calcium; Chloride Channels; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dibutyryl Cyclic GMP; Enzyme Activation; Female; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Oocytes; Protein Kinase C; Tetradecanoylphorbol Acetate; Type C Phospholipases; Xenopus laevis | 1995 |
Modification of frequency augmentation-potentiation by GTP gamma S in the frog neuromuscular junction.
Topics: Action Potentials; Aluminum Compounds; Animals; Cell Line; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Neuromuscular Junction; Ranidae; Thionucleotides | 1995 |
Phosphatase is responsible for run down, and probably G protein-mediated inhibition of inwardly rectifying K+ currents in guinea pig chromaffin cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Alkaline Phosphatase; Aluminum Compounds; Animals; Chromaffin System; Down-Regulation; Electrophysiology; Female; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Guinea Pigs; Isoquinolines; Marine Toxins; Membrane Potentials; Oxazoles; Patch-Clamp Techniques; Phosphoprotein Phosphatases; Phosphorylation; Piperazines; Potassium Channel Blockers; Potassium Channels; Protein Phosphatase 1; Sulfonamides | 1995 |
Catalytic activation of guanylate cyclase/atrial natriuretic factor receptor by combined effects of ANF and GTP gamma S in plasma membranes of Leydig tumor cells: involvement of G-proteins.
Topics: Aluminum Compounds; Animals; Atrial Natriuretic Factor; Benzalkonium Compounds; Cell Membrane; Dose-Response Relationship, Drug; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylate Cyclase; Intercellular Signaling Peptides and Proteins; Leydig Cell Tumor; Mice; Nucleotides; Peptides; Rats; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Tumor Cells, Cultured; Wasp Venoms | 1995 |
TNF-alpha stimulates increased plasma membrane guanine nucleotide binding protein activity in polymorphonuclear leukocytes.
Topics: Cell Membrane; Cholera Toxin; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Humans; In Vitro Techniques; Neutrophils; Pertussis Toxin; Phospholipase D; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Signal Transduction; Superoxides; Time Factors; Tumor Necrosis Factor-alpha; Virulence Factors, Bordetella | 1995 |
In vitro reconstitution of phagosome-endosome fusion: evidence for regulation by heterotrimeric GTPases.
Topics: Aluminum Compounds; Cell Line; Cholera Toxin; Endosomes; Fluorides; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Intracellular Membranes; Macromolecular Substances; Membrane Fusion; NAD; Phagosomes; Potassium Chloride | 1995 |
Mechanism of GTP hydrolysis by G-protein alpha subunits.
Topics: Aluminum Compounds; Amino Acid Sequence; Base Sequence; Conserved Sequence; DNA; Escherichia coli; Fluorides; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Hydrolysis; Kinetics; Macromolecular Substances; Magnesium; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phosphorus Radioisotopes; Proto-Oncogene Proteins p21(ras); Recombinant Proteins; Signal Transduction; Time Factors | 1994 |
Palmitoylation but not the extreme amino-terminus of Gq alpha is required for coupling to the NK2 receptor.
Topics: Aluminum Compounds; Animals; Cell Line; Cytidine Diphosphate Diglycerides; Detergents; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Mutagenesis; Palmitic Acid; Palmitic Acids; Plasmids; Receptors, Neurokinin-2; Recombinant Proteins; Solubility; Structure-Activity Relationship; Transfection; Type C Phospholipases | 1994 |
Requirement for intramolecular domain interaction in activation of G protein alpha subunit by aluminum fluoride and GDP but not by GTP gamma S.
Topics: Aluminum Compounds; Amino Acid Sequence; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Molecular Sequence Data | 1994 |
Mode of regulation by G protein of the ATP-sensitive K+ channel in guinea-pig ventricular cell membrane.
Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Aluminum Compounds; Animals; Cells, Cultured; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Heart; Heart Ventricles; Kinetics; Potassium Channels; Time Factors | 1994 |
GTPase mechanism of Gproteins from the 1.7-A crystal structure of transducin alpha-GDP-AIF-4.
Topics: Aluminum Compounds; Animals; Cattle; Computer Graphics; Crystallography, X-Ray; Fluorides; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Hydrolysis; Mutagenesis; Protein Conformation; Transducin; Water | 1994 |
Guanosine 5'-[gamma-thio]triphosphate induces membrane localization of cytosol-independent phospholipase D activity in a cell-free system from U937 promonocytic leucocytes.
Topics: Adenosine Triphosphate; Aluminum Compounds; Calcium; Cell Line; Cell Membrane; Cell Membrane Permeability; Cell-Free System; Cytosol; Drug Synergism; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Humans; Monocytes; Phospholipase D | 1994 |
Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis.
Topics: Aluminum Compounds; Arginine; Binding Sites; Catalysis; Computer Graphics; Crystallography, X-Ray; Fluorides; Glutamine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Helix-Loop-Helix Motifs; Hydrogen Bonding; Hydrolysis; Models, Molecular; Protein Conformation; Protein Structure, Secondary | 1994 |
Aluminum fluoride and magnesium, activators of heterotrimeric GTP-binding proteins, affect high-affinity binding of the fungal toxin fusicoccin to the fusicoccin-binding protein in oat root plasma membranes.
Topics: Acetone; Aluminum Compounds; Binding Sites; Cell Membrane; Edible Grain; Fluorides; Glucosides; Glycosides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Magnesium; Plant Proteins; Receptors, Cell Surface; Signal Transduction; Sodium Fluoride | 1994 |
Binding of the cytosolic p200 protein to Golgi membranes is regulated by heterotrimeric G proteins.
Topics: Aluminum Compounds; Animals; Cell Compartmentation; Coatomer Protein; Cytosol; Fluorescent Antibody Technique; Fluorides; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Intercellular Signaling Peptides and Proteins; Intracellular Membranes; Kidney; Liver; Microsomes; Microtubule-Associated Proteins; Peptides; Pertussis Toxin; Protein Binding; Rats; Swine; Virulence Factors, Bordetella; Wasp Venoms | 1993 |
Fluoride prevents degranulation of the azurophilic and specific granules in electropermeabilized neutrophils.
Topics: Antigens, CD; Antigens, Neoplasm; Cell Adhesion Molecules; Cell Degranulation; Ethers, Cyclic; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Membrane Glycoproteins; Neutrophils; Okadaic Acid; Permeability; Platelet Membrane Glycoproteins; Tetraspanin 30 | 1994 |
G proteins activate ATP-sensitive K+ channels by antagonizing ATP-dependent gating.
Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Aluminum Compounds; Animals; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guinea Pigs; Inosine Diphosphate; Ion Channel Gating; Potassium Channels; Thionucleotides; Uridine Diphosphate | 1994 |
Activation of phospholipase D by guanosine 5'[gamma-thio]triphosphate and AlF4- in bovine corneal epithelial cells.
Topics: Aluminum Compounds; Animals; Cattle; Cells, Cultured; Cornea; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Epithelial Cells; Epithelium; Fluorides; Glycerophospholipids; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Microsomes; Myristic Acid; Myristic Acids; Phorbol 12,13-Dibutyrate; Phosphatidic Acids; Phospholipase D | 1994 |
Evidence that v-Src-induced phospholipase D activity is mediated by a G protein.
Topics: 3T3 Cells; Adenine Nucleotides; Aluminum Compounds; Animals; Arachidonic Acid; Avian Sarcoma Viruses; Benzoquinones; Cell Line, Transformed; Cholera Toxin; Enzyme Induction; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Kinetics; Lactams, Macrocyclic; Mice; Mice, Inbred BALB C; Myristic Acid; Myristic Acids; Oncogene Protein pp60(v-src); Phosphatidylcholines; Phospholipase D; Protein-Tyrosine Kinases; Quinones; Rifabutin; Tetradecanoylphorbol Acetate; Thionucleotides; Virulence Factors, Bordetella | 1994 |
Tryptophan W207 in transducin T alpha is the fluorescence sensor of the G protein activation switch and is involved in the effector binding.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Aluminum Compounds; Amino Acid Sequence; Animals; Baculoviridae; DNA Mutational Analysis; Enzyme Activation; Fluorescence; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Models, Molecular; Molecular Sequence Data; Moths; Protein Conformation; Recombinant Proteins; Rod Cell Outer Segment; Sequence Homology, Amino Acid; Signal Transduction; Transducin; Tryptophan | 1993 |
Inhibition by the protein kinase C activator 4 beta-phorbol 12-myristate 13-acetate of the prostaglandin F2 alpha-mediated and noradrenaline-mediated but not glucagon-mediated activation of glycogenolysis in rat liver.
Topics: Aluminum Compounds; Animals; Dinoprost; Enzyme Activation; Fluorides; Glucagon; Glucose; Glycogen; Guanosine 5'-O-(3-Thiotriphosphate); Inositol 1,4,5-Trisphosphate; Lactates; Lactic Acid; Liver; Male; Norepinephrine; Phosphorylases; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1993 |
On the role of G protein activation and phosphorylation in desensitization to acetylcholine in guinea-pig atrial cells.
Topics: Acetylcholine; Aluminum Compounds; Animals; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Heart; Heart Atria; Myocardium; Phosphorylation; Temperature | 1993 |
Agonist-induced, GTP-dependent phosphoinositide hydrolysis in postmortem human brain membranes.
Topics: Adenosine Triphosphate; Aged; Aluminum Compounds; Brain; Calcium; Carbachol; Cell Membrane; Cycloleucine; Female; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Histamine; Humans; Hydrolysis; Male; Neurotoxins; Phosphatidylinositols; Pilocarpine; Postmortem Changes; Second Messenger Systems; Serotonin; Type C Phospholipases | 1994 |
Nanomolar arachidonic acid influences the respiratory burst in eosinophils and neutrophils induced by GTP-binding protein. A comparative study of the respiratory burst in bovine eosinophils and neutrophils.
Topics: Aluminum Compounds; Animals; Arachidonic Acid; Cattle; Doxorubicin; Enzyme Activation; Enzyme Induction; Eosinophils; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Luminescent Measurements; Luminol; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phospholipases A; Phospholipases A2; Respiratory Burst; Staphylococcus aureus; Type C Phospholipases | 1993 |
Guanine nucleotide-binding protein stimulates arachidonic acid metabolism in TEA3A1 thymic epithelial cells by stimulating release and inhibiting incorporation of arachidonic acid.
Topics: Aluminum Compounds; Animals; Arachidonic Acid; Blotting, Western; Cell Line; Diglycerides; Dinoprostone; Epithelial Cells; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Phospholipases A; Phospholipases A2; Phospholipids; Protein Kinase C; Rats; Thymus Gland; Type C Phospholipases | 1993 |
Regulation of phospholipase A2 activity in undifferentiated and neutrophil-like HL60 cells. Linkage between impaired responses to agonists and absence of protein kinase C-dependent phosphorylation of cytosolic phospholipase A2.
Topics: Adenosine Triphosphate; Aluminum Compounds; Arachidonic Acid; Blotting, Western; Bucladesine; Calcimycin; Calcium; Cell Differentiation; Cell Line; Cytosol; Electrophoresis, Polyacrylamide Gel; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; Leukemia, Promyelocytic, Acute; Neutrophils; Phospholipases A; Phospholipases A2; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
A G protein-activated K+ current in bovine adrenal chromaffin cells: possible regulatory role in exocytosis.
Topics: Adrenal Glands; Aluminum Compounds; Animals; Calcium; Catecholamines; Cattle; Cells, Cultured; Chromaffin Granules; Exocytosis; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Potassium Channels | 1994 |
Activated release of membrane-anchored TGF-alpha in the absence of cytosol.
Topics: Aluminum; Aluminum Compounds; Animals; Cell Membrane; Cell Membrane Permeability; CHO Cells; Cricetinae; Fluorides; Fluorine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Kinetics; Protein Kinase C; Protein Precursors; Protein Processing, Post-Translational; Rats; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thionucleotides; Transfection; Transforming Growth Factor alpha | 1993 |
Halothane regulates G-protein-dependent phospholipase C activity in turkey erythrocyte membranes.
Topics: Aluminum; Aluminum Compounds; Animals; Enzyme Activation; Erythrocyte Membrane; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Halothane; Inositol Phosphates; Kinetics; Membrane Lipids; Signal Transduction; Turkeys; Type C Phospholipases | 1993 |
Stimulus-induced dissociation of alpha subunits of heterotrimeric GTP-binding proteins from the cytoskeleton of human neutrophils.
Topics: Cell Membrane Permeability; Cytoskeleton; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Protein Conformation; Signal Transduction; Virulence Factors, Bordetella | 1993 |
Transmembrane signaling in human polymorphonuclear neutrophils: 15(S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid modulates receptor agonist-triggered cell activation.
Topics: Aluminum; Aluminum Compounds; Calcium; Cell Degranulation; Cell Membrane; Cyclic AMP; Fluorides; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Intercellular Signaling Peptides and Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptides; Protein Kinase C; Respiratory Burst; Signal Transduction; Wasp Venoms | 1993 |
Purification and characterization of recombinant G16 alpha from Sf9 cells: activation of purified phospholipase C isozymes by G-protein alpha subunits.
Topics: Aluminum; Animals; Cell Line; Chromatography, Ion Exchange; Cloning, Molecular; Enzyme Activation; Fluorides; Gene Transfer Techniques; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Isoenzymes; Kinetics; Macromolecular Substances; Magnesium; Moths; Recombinant Proteins; Restriction Mapping; Tumor Cells, Cultured; Type C Phospholipases | 1993 |
Multiple GTP-binding proteins participate in clathrin-coated vesicle-mediated endocytosis.
Topics: Aluminum; Aluminum Compounds; Amino Acid Sequence; Coated Pits, Cell-Membrane; Endocytosis; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Humans; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Molecular Sequence Data; Peptides; Receptors, Transferrin; Thionucleotides; Tumor Cells, Cultured; Wasp Venoms | 1993 |
Chronic ethanol treatment increases expression of inhibitory G-proteins and reduces adenylylcyclase activity in the central nervous system of two lines of ethanol-sensitive mice.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Brain; Cell Membrane; Cerebellum; Colforsin; Corticotropin-Releasing Hormone; Ethanol; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Mice; Mice, Mutant Strains; Pertussis Toxin; Signal Transduction; Virulence Factors, Bordetella | 1993 |
A functional role for GTP-binding proteins in synaptic vesicle cycling.
Topics: Aluminum; Aluminum Compounds; Animals; Calcium; Decapodiformes; Fluorides; Fluorine; Ganglia; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; In Vitro Techniques; Kinetics; Models, Neurological; Nerve Endings; Signal Transduction; Synaptic Vesicles; Thionucleotides; Time Factors | 1993 |
Identification of G alpha 11 as the phospholipase C-activating G-protein of turkey erythrocytes.
Topics: Aluminum; Aluminum Compounds; Amino Acid Sequence; Animals; Baculoviridae; Base Sequence; Chromatography, High Pressure Liquid; DNA; Enzyme Activation; Erythrocytes; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Molecular Sequence Data; Moths; Recombinant Proteins; Sequence Homology, Amino Acid; Transfection; Turkeys; Type C Phospholipases | 1993 |
Intracellular Cl- modulates Ca2+-induced exocytosis from rat melanotrophs through GTP-binding proteins.
Topics: Aluminum Compounds; Animals; Calcium; Cells, Cultured; Chlorides; Cytosol; Electrophysiology; Exocytosis; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Melanocytes; Patch-Clamp Techniques; Pertussis Toxin; Rats; Thionucleotides; Virulence Factors, Bordetella | 1995 |
Stimulatory regulation of the large-conductance, calcium-activated potassium channel by G proteins in bovine adrenal chromaffin cells.
Topics: Adrenal Medulla; Aluminum Compounds; Animals; Calcium; Cattle; Cell Membrane; Cells, Cultured; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Homeostasis; Ion Channel Gating; Kinetics; Large-Conductance Calcium-Activated Potassium Channels; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Calcium-Activated; Time Factors; Virulence Factors, Bordetella | 1996 |
Differential effects of G-protein activators on 5-hydroxytryptamine and platelet-derived growth factor release from streptolysin-O-permeabilized human platelets.
Topics: Aluminum Compounds; Bacterial Proteins; Blood Platelets; Calcium; Cell Membrane Permeability; Cytoplasmic Granules; Diglycerides; Egtazic Acid; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; L-Lactate Dehydrogenase; Phosphatidic Acids; Platelet-Derived Growth Factor; Serotonin; Streptolysins | 1996 |
Direct or C5a-induced activation of heterotrimeric Gi2 proteins in human neutrophils is associated with interaction between formyl peptide receptors and the cytoskeleton.
Topics: Aluminum Compounds; Complement C5a; Cytoskeleton; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Thionucleotides | 1996 |
Nonhydrolyzable analogues of GTP activate a new Na+ current in a rat mast cell line.
Topics: Animals; Biological Transport; Cell Membrane Permeability; Cell Polarity; Electric Conductivity; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hydrolysis; Mast Cells; Patch-Clamp Techniques; Rats; Second Messenger Systems; Sodium; Sodium Channels; Thionucleotides; Tumor Cells, Cultured | 1996 |
Real-time fluorescence measurement of cell-free endosome fusion: regulation by second messengers.
Topics: Adenosine Triphosphate; Aluminum Compounds; Animals; Biophysical Phenomena; Biophysics; Boron Compounds; Calmodulin; Cattle; Cell Line; Cell-Free System; Cricetinae; Cyclic AMP; Cytosol; Endosomes; Ethylmaleimide; Fluorescent Dyes; Fluorides; Fluorometry; Guanosine 5'-O-(3-Thiotriphosphate); Membrane Fusion; Protein Kinases; Second Messenger Systems | 1996 |
The mammalian ARF-like protein 1 (Arl1) is associated with the Golgi complex.
Topics: ADP-Ribosylation Factors; Aluminum Compounds; Amino Acid Sequence; Animals; Antibodies; Base Sequence; Blotting, Northern; Brefeldin A; Cell Line; Cell Nucleus; CHO Cells; Cloning, Molecular; Cricetinae; Cyclopentanes; DNA, Complementary; Fluorides; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); L Cells; LLC-PK1 Cells; Mammals; Mice; Molecular Sequence Data; Nocodazole; Rabbits; Rats; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Swine | 1996 |
1,25(OH)2-vitamin D3 stimulation of phospholipases C and D in muscle cells involves extracellular calcium and a pertussis-sensitive G protein.
Topics: Aluminum Compounds; Animals; Arachidonic Acid; Calcitriol; Calcium; Calcium Channel Blockers; Chick Embryo; Diglycerides; Fluorides; Glycerol; Glycerophospholipids; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Muscles; Pertussis Toxin; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylinositol 4,5-Diphosphate; Phospholipase D; Type C Phospholipases; Virulence Factors, Bordetella | 1996 |
The GTPase-activating protein RGS4 stabilizes the transition state for nucleotide hydrolysis.
Topics: Aluminum Compounds; Animals; Fluorides; GTP Phosphohydrolases; GTP-Binding Proteins; GTPase-Activating Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Kinetics; Mammals; Proteins; Recombinant Proteins; RGS Proteins | 1996 |
Effect of morphine on secretion of amylase from isolated parotid acini.
Topics: Affinity Labels; Aluminum Compounds; Amylases; Animals; Azides; Bacterial Toxins; Bucladesine; Cyclic AMP; Fluorides; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hemolysin Proteins; In Vitro Techniques; Morphine; Neurotoxins; Parotid Gland; Rats; Rats, Sprague-Dawley | 1996 |
Receptor and betagamma binding sites in the alpha subunit of the retinal G protein transducin.
Topics: Aluminum Compounds; Animals; Binding Sites; COS Cells; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Models, Molecular; Mutation; Phenotype; Protein Conformation; Retinaldehyde; Rhodopsin; Rod Cell Outer Segment; Transducin | 1997 |
p230 is associated with vesicles budding from the trans-Golgi network.
Topics: Aluminum Compounds; Animals; Autoantibodies; Autoantigens; Brefeldin A; Cell Line; Cyclopentanes; Dogs; Fluorides; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); HeLa Cells; Humans; Membrane Proteins; Microscopy, Electron | 1996 |
Exotoxin-insensitive G proteins mediate synaptically evoked muscarinic sodium current in rabbit sympathetic neurones.
Topics: Animals; Cells, Cultured; Cholera Toxin; Electrophysiology; Exotoxins; Fluorides; Ganglia, Sympathetic; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Membrane Potentials; Muscarinic Agonists; Patch-Clamp Techniques; Pertussis Toxin; Rabbits; Receptors, Muscarinic; Sodium Channels; Sympathetic Nervous System; Synapses; Thionucleotides; Virulence Factors, Bordetella | 1997 |
Different mechanisms regulate phosphatidylserine synthesis in rat cerebral cortex.
Topics: Aluminum Compounds; Animals; Cerebral Cortex; Female; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Mice; Phosphatidylserines; Rats; Rats, Sprague-Dawley | 1997 |
Down-regulation of G-protein-mediated Ca2+ sensitization in smooth muscle.
Topics: Aluminum Compounds; Animals; Antifungal Agents; Bacterial Toxins; Calcium; Detergents; Down-Regulation; Endothelins; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hemolysin Proteins; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Myosin Light Chains; Phenylephrine; Phorbol 12,13-Dibutyrate; Phosphoric Monoester Hydrolases; Phosphorylation; Portal Vein; Precipitin Tests; Protein Kinase C; Proto-Oncogene Proteins p21(ras); Pyrans; Rabbits; rhoA GTP-Binding Protein; Solubility; Spiro Compounds; Time Factors | 1997 |
ATP-dependent formation of free synaptic vesicles from PC12 membranes in vitro.
Topics: Adenosine Triphosphate; Aluminum Compounds; Animals; Brefeldin A; Cell-Free System; Cyclopentanes; Cytosol; Enzyme-Linked Immunosorbent Assay; Ethylmaleimide; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; PC12 Cells; Protein Synthesis Inhibitors; Rats; Synaptic Vesicles; Temperature | 1997 |
Cardiac G-protein receptor kinase activity: effect of a beta-adrenergic receptor antagonist.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Aluminum Compounds; Animals; Binding, Competitive; Bisoprolol; Colforsin; Enzyme Activation; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoproterenol; Myocardium; Receptor Protein-Tyrosine Kinases; Receptors, Adrenergic, beta; Swine | 1998 |
Intracellular Cl- dependence of Na-H exchange in barnacle muscle fibers under normotonic and hypertonic conditions.
Topics: Aluminum Compounds; Animals; Chlorides; Cholera Toxin; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Hypertonic Solutions; Intracellular Membranes; Muscle Fibers, Skeletal; Reference Values; Sodium-Hydrogen Exchangers; Thoracica | 1997 |
Prostaglandin H synthase: protein synthesis-independent regulation in bovine aortic endothelial cells.
Topics: Aluminum Compounds; Animals; Aorta; Aspirin; Cattle; Cells, Cultured; Cycloheximide; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dactinomycin; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Fibroblast Growth Factor 2; Fluorides; Genistein; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Isoenzymes; Kinetics; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Sodium Fluoride; Sulfonamides; Time Factors; Vanadates | 1997 |
Protein kinase A regulates the disposition of Ca2+ which enters the cytoplasmic space through store-activated Ca2+ channels in rat hepatocytes by diverting inflowing Ca2+ to mitochondria.
Topics: Adenosine Triphosphate; Aluminum Compounds; Animals; Bucladesine; Calcium; Calcium Channels; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoplasm; Enzyme Inhibitors; Fluorides; Genistein; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Liver; Mitochondria, Liver; Rats; Thapsigargin; Vasopressins | 1998 |
Fluoride stimulates cystic fibrosis transmembrane conductance regulator Cl- channel activity.
Topics: 3T3 Cells; Animals; Cystic Fibrosis Transmembrane Conductance Regulator; Cytosol; Enzyme Activation; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Mice; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Phosphoric Monoester Hydrolases | 1998 |
The two phases of regulated exocytosis in permeabilized pancreatic acini are modulated differently by heterotrimeric G-proteins.
Topics: Adenosine Triphosphate; Aluminum Compounds; Amylases; Animals; Calcium; Cell Membrane Permeability; Cells, Cultured; Exocytosis; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Pancreas; Protein Conformation; ras Proteins; Rats; Type C Phospholipases | 1998 |
p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13.
Topics: Aluminum Compounds; Amino Acid Sequence; Animals; Fluorides; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, G12-G13; GTP-Binding Proteins; Guanine Nucleotide Exchange Factors; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Humans; Hydrolysis; Molecular Sequence Data; Proteins; Recombinant Fusion Proteins; Sequence Alignment; Signal Transduction | 1998 |
Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13.
Topics: Aluminum Compounds; Animals; COS Cells; Fluorides; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, G12-G13; GTP-Binding Proteins; Guanine Nucleotide Exchange Factors; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Proteins; Recombinant Fusion Proteins; Recombinant Proteins; Signal Transduction | 1998 |
A novel mutation in the switch 3 region of Gsalpha in a patient with Albright hereditary osteodystrophy impairs GDP binding and receptor activation.
Topics: Adenylyl Cyclases; Adult; Alanine; Aluminum Compounds; Amino Acid Sequence; Arginine; Base Sequence; Binding Sites; Cloning, Molecular; Erythrocyte Membrane; Escherichia coli; Exons; Female; Fibrous Dysplasia, Polyostotic; Fluorides; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Male; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Polymerase Chain Reaction; Protein Biosynthesis; Protein Structure, Secondary; Receptors, Cell Surface; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Tryptophan | 1998 |
In vitro reconstitution of microtubule plus end-directed, GTPgammaS-sensitive motility of Golgi membranes.
Topics: Adenylyl Imidodiphosphate; Aluminum Compounds; Animals; Chlamydomonas reinhardtii; Cholera Toxin; Cytosol; Flagella; Fluorides; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Intracellular Membranes; Liver; Microscopy, Electron; Microscopy, Video; Microsomes, Liver; Microtubules; Movement; Rats; Virulence Factors, Bordetella | 1998 |
Intracellular dynamics of alkaline phosphatase-containing granules in electropermeabilized human neutrophils.
Topics: Alkaline Phosphatase; Aluminum Compounds; Botulinum Toxins; Cytoplasmic Granules; Egtazic Acid; Fluorescent Antibody Technique, Indirect; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hydrogen Peroxide; Microscopy, Electron; Microtubules; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nocodazole; Permeability; Pertussis Toxin; Superoxides; Up-Regulation; Virulence Factors, Bordetella | 1998 |
Halothane attenuates calcium sensitization in airway smooth muscle by inhibiting G-proteins.
Topics: Acetylcholine; ADP Ribose Transferases; Aluminum Compounds; Anesthetics, Inhalation; Animals; Botulinum Toxins; Calcium; Dogs; Escin; Female; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Halothane; In Vitro Techniques; Isometric Contraction; Male; Muscle, Smooth; Trachea | 1998 |
Mutagenesis of the conserved residue Glu259 of Gsalpha demonstrates the importance of interactions between switches 2 and 3 for activation.
Topics: Aluminum Compounds; Animals; Base Sequence; Cattle; Conserved Sequence; DNA Primers; Fluorides; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Kinetics; Magnesium; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Recombinant Proteins | 1999 |
The thrombospondin receptor integrin-associated protein (CD47) functionally couples to heterotrimeric Gi.
Topics: Aluminum Compounds; Antigens, CD; Carrier Proteins; CD47 Antigen; Cyclic AMP; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Membrane Proteins; Peptide Fragments; Precipitin Tests; Protein Binding; Receptors, Vitronectin; Thrombospondins; Tumor Cells, Cultured | 1999 |
A mutation in the heterotrimeric stimulatory guanine nucleotide binding protein alpha-subunit with impaired receptor-mediated activation because of elevated GTPase activity.
Topics: Adenylyl Cyclases; Aluminum Compounds; Amino Acid Substitution; Animals; Arginine; Cattle; Cloning, Molecular; Escherichia coli; Fibrous Dysplasia, Polyostotic; Fluorides; Glutamine; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Isoproterenol; Kinetics; Macromolecular Substances; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Protein Structure, Secondary; Recombinant Proteins | 1999 |
Trimeric G proteins modulate the dynamic interaction of PKAII with the Golgi complex.
Topics: Aluminum Compounds; Animals; Brefeldin A; Cattle; COS Cells; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Fluorescent Antibody Technique; Fluorides; Golgi Apparatus; Guanosine 5'-O-(3-Thiotriphosphate); Heterotrimeric GTP-Binding Proteins; Intercellular Signaling Peptides and Proteins; Intracellular Membranes; Male; Peptides; Protein Binding; Temperature; Wasp Venoms | 1999 |
Aluminum fluoride inhibits phospholipase D activation by a GTP-binding protein-independent mechanism.
Topics: ADP-Ribosylation Factor 1; Aluminum Compounds; Animals; Enzyme Activation; Enzyme Inhibitors; Fluorides; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Male; Oleic Acid; Phospholipase D; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Submandibular Gland | 1999 |
G alpha t/G alpha i1 chimeras used to define structural basis of specific functions of G alpha t.
Topics: Aluminum Compounds; Amino Acid Substitution; Cloning, Molecular; Escherichia coli; Fluorides; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Kinetics; Models, Molecular; Polymerase Chain Reaction; Protein Conformation; Protein Structure, Secondary; Recombinant Fusion Proteins; Restriction Mapping; Transducin | 2000 |
Stimulation of Ca(2+)-independent exocytosis in rat pituitary gonadotrophs by G-protein.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aluminum Compounds; Animals; Calcium; Calcium-Transporting ATPases; Cyclic AMP; Cytoplasmic Granules; Cytosol; Egtazic Acid; Enzyme Inhibitors; Exocytosis; Fluorides; Fluorometry; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Male; Patch-Clamp Techniques; Photolysis; Pituitary Gland, Anterior; Protein Kinase C; Rats; Staurosporine | 2000 |
Apical heterotrimeric g-proteins activate CFTR in the native sweat duct.
Topics: Adenosine Triphosphate; Adult; Aluminum Compounds; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Heterotrimeric GTP-Binding Proteins; Humans; Immunohistochemistry; In Vitro Techniques; Male; Mutation; Sodium Channels; Sodium-Potassium-Exchanging ATPase; Sweat Glands | 2001 |
RGS12 and RGS14 GoLoco motifs are G alpha(i) interaction sites with guanine nucleotide dissociation inhibitor Activity.
Topics: Aluminum Compounds; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Biosensing Techniques; Cloning, Molecular; Escherichia coli; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Heterotrimeric GTP-Binding Proteins; Kinetics; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligopeptides; Open Reading Frames; Rats; Recombinant Proteins; RGS Proteins; Signal Transduction; Surface Plasmon Resonance | 2001 |
Biochemical analysis of yeast G(alpha) mutants that enhance adaptation to pheromone.
Topics: Adaptation, Physiological; Alleles; Aluminum Compounds; Amino Acid Substitution; Binding Sites; Chromatography, Affinity; Down-Regulation; Fluorides; GTP-Binding Protein alpha Subunits; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Heterotrimeric GTP-Binding Proteins; Histidine; Models, Molecular; Mutation; Pheromones; Protein Binding; Receptors, Mating Factor; Receptors, Peptide; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Transcription Factors | 2001 |
Regulators of GTP-binding proteins cause morphological changes in the vacuole system of the filamentous fungus, Pisolithus tinctorius.
Topics: Aluminum Compounds; Basidiomycota; Brefeldin A; Cytoskeleton; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Hyphae; Protein Synthesis Inhibitors; Thionucleotides; Transport Vesicles; Vacuoles | 2002 |
S111N mutation in the helical domain of human Gs(alpha) reduces its GDP/GTP exchange rate.
Topics: Adenylyl Cyclases; Aluminum Compounds; Amino Acid Substitution; Asparagine; Fluorides; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Humans; Models, Molecular; Point Mutation; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Cell Surface; Serine; Trypsin | 2002 |
Dual effects of hexanol and halothane on the regulation of calcium sensitivity in airway smooth muscle.
Topics: Aluminum Compounds; Anesthetics, Inhalation; Animals; Calcium; Cell Membrane Permeability; Dogs; Female; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Halothane; Hexanols; In Vitro Techniques; Isometric Contraction; Male; Muscle, Smooth; Myosin Light Chains; Pertussis Toxin; Phosphorylation; Receptors, Muscarinic; Respiratory System; Type C Phospholipases | 2003 |
The myristoylated amino terminus of Galpha(i)(1) plays a critical role in the structure and function of Galpha(i)(1) subunits in solution.
Topics: Aluminum Compounds; Cysteine; DNA Primers; Electron Spin Resonance Spectroscopy; Electrophoresis, Polyacrylamide Gel; Fluorescent Dyes; Fluorides; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Models, Molecular; Mutagenesis, Site-Directed; Myristic Acid; Protein Binding; Protein Conformation; Spin Labels; Structure-Activity Relationship; Sulfhydryl Compounds | 2003 |
Time-dependent inhibition of G protein-coupled receptor signaling by local anesthetics.
Topics: Aluminum Compounds; Anesthetics, Local; Animals; Chloride Channels; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Lysophospholipids; Phosphoric Monoester Hydrolases; Platelet Activating Factor; Protein Kinase C; Receptors, Cell Surface; Signal Transduction; Time Factors; Xenopus laevis | 2004 |
Purification and in vitro functional analyses of RGS12 and RGS14 GoLoco motif peptides.
Topics: Aluminum Compounds; Amino Acid Sequence; Animals; Base Sequence; Fluorescence Resonance Energy Transfer; Fluorides; GTP-Binding Protein alpha Subunits; Guanosine 5'-O-(3-Thiotriphosphate); Molecular Sequence Data; Peptides; Rats; Recombinant Fusion Proteins; RGS Proteins; Sequence Alignment; Spectrometry, Fluorescence | 2004 |
Uncoupling of GPCR and RhoA-induced Ca2+-sensitization of chicken amnion smooth muscle lacking CPI-17.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aluminum Compounds; Amnion; Animals; Bacterial Toxins; Calcium; Chickens; Cyclic GMP; Enzyme Activation; Enzyme Inhibitors; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Muscle Contraction; Muscle Proteins; Muscle, Smooth; Myosin-Light-Chain Phosphatase; Phosphoprotein Phosphatases; Phosphoproteins; Protein Phosphatase 1; Protein Subunits; Receptors, G-Protein-Coupled; rhoA GTP-Binding Protein; Signal Transduction; Vasoconstrictor Agents | 2004 |
Activation of BK channels in GH3 cells by a c-PLA2-dependent G-protein signaling pathway.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aluminum Compounds; Animals; Arachidonic Acids; Calcium; Cell Line, Tumor; Drug Interactions; Enzyme Inhibitors; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Ion Channel Gating; Isoproterenol; Membrane Potentials; Models, Biological; Oligodeoxyribonucleotides, Antisense; Patch-Clamp Techniques; Phospholipases A; Phospholipases A2; Picrotoxin; Pituitary Gland; Potassium Channels, Calcium-Activated; Propranolol; Rats; Signal Transduction; Time Factors | 2005 |
A switch 3 point mutation in the alpha subunit of transducin yields a unique dominant-negative inhibitor.
Topics: Aluminum Compounds; Animals; Arginine; Catalysis; Cattle; Chromatography, High Pressure Liquid; Cyclic GMP; Dose-Response Relationship, Drug; Fluorides; Genes, Dominant; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Models, Biological; Models, Molecular; Mutation; Nucleotides; Point Mutation; Protein Conformation; Recombinant Fusion Proteins; Recombinant Proteins; Retina; Rhodopsin; Signal Transduction; Spectrometry, Fluorescence; Time Factors; Transducin; Trypsin | 2005 |