fluorescein-5-isothiocyanate has been researched along with methotrexate in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (17.86) | 18.7374 |
| 1990's | 2 (7.14) | 18.2507 |
| 2000's | 10 (35.71) | 29.6817 |
| 2010's | 8 (28.57) | 24.3611 |
| 2020's | 3 (10.71) | 2.80 |
| Authors | Studies |
|---|---|
| Daniel, J; Dyson, JE; McLaughlin, JB; Simmons, DM; Surrey, CR | 1 |
| Kerwar, SS; Webber, S; Whiteley, JM | 1 |
| Midoux, P; Monsigny, M; Roche, AC | 1 |
| Ishizaki, Y; Nishiya, I; Nunokawa, S; Saitoh, S; Yamashita, K | 1 |
| Henderson, GB; Russell, A; Whiteley, JM | 1 |
| Horie, T; Masubuchi, Y; Nakamaru, M | 1 |
| Dixkens, C; Hameister, H; Keller, T; Posseckert, G | 1 |
| Awazu, S; Fuwa, T; Horie, T; Itakura, Y | 1 |
| Barlési, F; Clerc, T; D'journo, B; Doddoli, C; Ghez, O; Robitail, S; Thomas, P | 1 |
| Baker, JR; Bielinska, A; Kotlyar, A; Kukowska-Latallo, JF; Majoros, IJ; Myc, A; Thomas, TP | 1 |
| Baker, JR; Islam, MT; Majoros, IJ | 1 |
| Gunduz, U; Gurhan, I; Hasirci, N; Muvaffak, A | 1 |
| Deutsch, M; Herman, S; Zurgil, N | 1 |
| Baker, JR; Majoros, IJ; Mehta, CB; Thomas, TP | 1 |
| Davidson, HJ; Freeman, LC; Iwamoto, T; Malreddy, P; Martin, J; Schultz, BD; Tomich, JM | 1 |
| Coran, AG; Karry, R; Lurie, M; Mogilner, JG; Shaoul, R; Shteinberg, D; Sukhotnik, I; Ure, BM | 1 |
| Hamada, K; Horie, T; Ito, K; Maeda, T; Miyazono, Y; Sekine, S | 1 |
| Baker, JR | 1 |
| Hamada, K; Horie, T; Sekine, S; Shitara, Y | 1 |
| Mori, N; Murakami, T; Yokooji, T | 1 |
| Galan, J; Hans, M; Hu, L; Iliuk, A; Tao, WA | 1 |
| Belmonte, L; Beutheu Youmba, S; Bôle-Feysot, C; Boukhettala, N; Coëffier, M; Déchelotte, P; Galas, L | 1 |
| Ahadi, F; Atyabi, F; Borougeni, AT; Dinarvand, R; Ghahremani, MH; Mansoori, P; Nouri, F; Ostad, SN; Taheri, A | 1 |
| Chen, Z; Du, LB; He, Z; Huang, SP; Jia, HY; Leng, ZH; Li, YC; Liu, Y; Zhou, JW; Zhuang, QF | 1 |
| Chen, Y; Li, B; Li, Z; Xu, W; Zhang, C | 1 |
| Ai, Y; Ding, M; Gao, J; Liang, Q; Wang, C; Wang, J; Wang, Y; Xie, R; Xiong, J; Zheng, W | 1 |
| Harada, T; Ito, K; Kasaoka, S; Kurakazu, T; Tanaka, Y | 1 |
| Dai, J; Li, D; Liang, L; Liu, J; Ren, J; Yang, C; Yu, J; Zhang, L | 1 |
1 review(s) available for fluorescein-5-isothiocyanate and methotrexate
| Article | Year |
|---|---|
Dendrimer-based nanoparticles for cancer therapy.
Topics: Animals; Antineoplastic Agents; Capillary Permeability; Carrier Proteins; Contrast Media; Dendrimers; DNA; Drug Carriers; Drug Delivery Systems; Drug Design; Fluorescein-5-isothiocyanate; Folate Receptors, GPI-Anchored; Humans; KB Cells; Methotrexate; Mice; Mice, Nude; Models, Molecular; Nanoparticles; Neoplasms; Receptors, Cell Surface; Tissue Distribution; Xenograft Model Antitumor Assays | 2009 |
27 other study(ies) available for fluorescein-5-isothiocyanate and methotrexate
| Article | Year |
|---|---|
Effects of hyperthermia, irradiation, and cytotoxic drugs on fluorescein isothiocyanate staining intensity for flow cytofluorometry.
Topics: Antineoplastic Agents; Cell Cycle; Cell Line; Cell Nucleus; Cell Survival; Computers; Doxorubicin; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluoresceins; Hot Temperature; Humans; Kinetics; Methotrexate; Proteins; Staining and Labeling; Thiocyanates | 1987 |
Synthesis and efficient isolation procedure for gamma-linked fluorescein methotrexate.
Topics: Animals; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, High Pressure Liquid; Fluorescein-5-isothiocyanate; Fluoresceins; Folic Acid Antagonists; Liver; Methotrexate; Rats; Spectrum Analysis; Structure-Activity Relationship; Thiocyanates | 1986 |
Uptake of neoglycoproteins via membrane lectin(s) of L1210 cells evidenced by quantitative flow cytofluorometry and drug targeting.
Topics: Animals; Cell Membrane; Cell Survival; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluoresceins; Fluorescent Dyes; Glycated Serum Albumin; Glycation End Products, Advanced; Hydrogen-Ion Concentration; Lectins; Leukemia L1210; Methotrexate; Mice; Serum Albumin; Thiocyanates | 1984 |
[Cell functions of cultured human choriocarcinoma following the administration of methotrexate (author's transl)].
Topics: Cell Cycle; Cells, Cultured; Choriocarcinoma; Chorionic Gonadotropin; DNA, Neoplasm; Female; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluoresceins; Humans; Methotrexate; Pregnancy; Thiocyanates; Trophoblastic Neoplasms; Uterine Neoplasms | 1981 |
A fluorescent derivative of methotrexate as an intracellular marker for dihydrofolate reductase in L1210 cells.
Topics: Animals; Biological Transport; Drug Resistance; Fluorescein-5-isothiocyanate; Fluoresceins; Fluorescent Dyes; Folic Acid Antagonists; Kinetics; Leukemia L1210; Methotrexate; Mice; Protein Binding; Thiocyanates | 1980 |
Docosahexaenoic acid exhibits a potent protection of small intestine from methotrexate-induced damage in mice.
Topics: Animals; Antimetabolites, Antineoplastic; Body Weight; Dextrans; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Fluorescein-5-isothiocyanate; Intestinal Absorption; Intestinal Diseases; Intestine, Small; Male; Methotrexate; Mice; Vitamin A | 1998 |
Structural analysis of the amplified IFN-beta and DHFR genes in a Chinese hamster ovary cell line using multicolour FISH analysis.
Topics: Animals; Blotting, Southern; CHO Cells; Chromosome Mapping; Cricetinae; DNA Probes; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Gene Amplification; Humans; In Situ Hybridization, Fluorescence; Interferon-beta; Karyotyping; Methotrexate; Recombinant Proteins; Tetrahydrofolate Dehydrogenase; Xanthenes | 1998 |
Alleviation by garlic of antitumor drug-induced damage to the intestine.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Dextrans; Fluorescein-5-isothiocyanate; Fluorouracil; Garlic; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Male; Methotrexate; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar | 2001 |
In vitro and in vivo methotrexate disposition in alveolar macrophages: comparison of pharmacokinetic parameters of two formulations.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Survival; Excipients; Flow Cytometry; Fluorescein-5-isothiocyanate; Injections, Spinal; Liposomes; Macrophages; Male; Methotrexate; Pulmonary Alveoli; Radioimmunoassay; Rats; Rats, Wistar; Tissue Distribution | 2005 |
Targeting and inhibition of cell growth by an engineered dendritic nanodevice.
Topics: Antineoplastic Agents; Cell Proliferation; Drug Carriers; Drug Delivery Systems; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Folic Acid; Humans; KB Cells; Methotrexate; Nanostructures; Polyamines | 2005 |
HPLC analysis of PAMAM dendrimer based multifunctional devices.
Topics: Chromatography, High Pressure Liquid; Dendrimers; Drug Delivery Systems; Fluorescein-5-isothiocyanate; Folic Acid; Methotrexate; Nanotechnology; Polyamines | 2005 |
Preparation and characterization of a biodegradable drug targeting system for anticancer drug delivery: microsphere-antibody conjugate.
Topics: Antibodies; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cell Line, Tumor; Cross-Linking Reagents; Drug Delivery Systems; Drug Stability; Excipients; Female; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Fluorouracil; Gelatin; Glutaral; Humans; Methotrexate; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Microspheres; Particle Size; Serum Albumin, Bovine | 2005 |
Low dose methotrexate induces apoptosis with reactive oxygen species involvement in T lymphocytic cell lines to a greater extent than in monocytic lines.
Topics: Acetylcysteine; Annexin A5; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Antioxidants; Apoptosis; Arthritis, Rheumatoid; Biological Assay; Cell Line, Tumor; Cell Proliferation; Cell Survival; Enzyme Inhibitors; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Immunosuppressive Agents; Jurkat Cells; Leukocytes; Methotrexate; Monocytes; Oxidative Stress; Propidium; Reactive Oxygen Species; T-Lymphocytes; Tetrazolium Salts; Thiazoles; Time Factors; U937 Cells | 2005 |
Poly(amidoamine) dendrimer-based multifunctional engineered nanodevice for cancer therapy.
Topics: Acetylation; Antineoplastic Agents; Dendrimers; Drug Carriers; Epoxy Compounds; Fluorescein-5-isothiocyanate; Folic Acid; Methotrexate; Nanostructures; Polyamines; Propanols | 2005 |
NC-1059: a channel-forming peptide that modulates drug delivery across in vitro corneal epithelium.
Topics: Cell Line, Transformed; Cell Membrane Permeability; Dextrans; Dose-Response Relationship, Drug; Electric Conductivity; Epithelium, Corneal; Fluorescein; Fluorescein-5-isothiocyanate; Humans; Ion Channels; Ion Transport; Membrane Potentials; Methotrexate; Peptides; Tight Junctions; Time Factors; Tissue Scaffolds | 2009 |
Leptin accelerates enterocyte turnover during methotrexate-induced intestinal mucositis in a rat.
Topics: Animals; Annexin A5; Apoptosis; bcl-2-Associated X Protein; Caco-2 Cells; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Enterocytes; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Ileum; Intestinal Mucosa; Jejunum; Leptin; Male; Methotrexate; Mucositis; Organ Size; Random Allocation; Rats; Rats, Sprague-Dawley; Recovery of Function; RNA, Messenger; Time Factors | 2009 |
Oxidative stress and enhanced paracellular permeability in the small intestine of methotrexate-treated rats.
Topics: Acetylcysteine; Animals; Antimetabolites, Antineoplastic; Body Weight; Dextrans; Fluorescein-5-isothiocyanate; Free Radical Scavengers; Glutathione; Injections, Intraperitoneal; Injections, Intravenous; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Male; Methotrexate; Oxidative Stress; Permeability; Rats; Rats, Wistar; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances; Time Factors | 2010 |
Zonula Occludens-1 alterations and enhanced intestinal permeability in methotrexate-treated rats.
Topics: Animals; Antimetabolites, Antineoplastic; Blotting, Western; Dextrans; Fluorescein-5-isothiocyanate; Immunohistochemistry; Immunoprecipitation; Inflammation; Intestinal Mucosa; Intestine, Small; Luminescence; Male; Membrane Proteins; Methotrexate; Permeability; Phosphoproteins; Phosphorylation; Rats; Rats, Wistar; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Tight Junctions; Tyrosine; Zonula Occludens-1 Protein | 2010 |
Study on absorption sites of quinidine and methotrexate in rat intestine.
Topics: Administration, Oral; Animals; Antimalarials; Biological Availability; Carrier Proteins; Dextrans; Duodenum; Fluorescein-5-isothiocyanate; Folic Acid Antagonists; Gastric Emptying; Hydrogen-Ion Concentration; Ileum; Intestinal Absorption; Jejunum; Male; Methotrexate; Molecular Weight; Quinidine; Rats; Rats, Sprague-Dawley | 2010 |
Identification of drug targets in vitro and in living cells by soluble-nanopolymer-based proteomics.
Topics: Amino Acid Sequence; Cell Line, Tumor; Dendrimers; Drug Discovery; Fluorescein-5-isothiocyanate; Humans; Methotrexate; Microscopy, Fluorescence; Molecular Sequence Data; Nanotechnology; Proteomics; Tandem Mass Spectrometry; Tetrahydrofolate Dehydrogenase | 2011 |
Methotrexate modulates tight junctions through NF-κB, MEK, and JNK pathways.
Topics: Animals; Apoptosis; Caco-2 Cells; Cell Membrane Permeability; Claudin-1; Dextrans; Fluorescein-5-isothiocyanate; Humans; Intestinal Mucosa; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Signaling System; Membrane Proteins; Methotrexate; NF-kappa B; Occludin; Rats; Rats, Sprague-Dawley; Tight Junctions | 2012 |
Targeted delivery of methotrexate to tumor cells using biotin functionalized methotrexate-human serum albumin conjugated nanoparticles.
Topics: Antineoplastic Agents; Biotin; Cell Survival; Drug Stability; Flow Cytometry; Fluorescein-5-isothiocyanate; HeLa Cells; Humans; Inhibitory Concentration 50; Methotrexate; Microscopy, Fluorescence; Nanoconjugates; Particle Size; Serum Albumin | 2011 |
Polyamidoamine dendrimer conjugated chitosan nanoparticles for the delivery of methotrexate.
Topics: Animals; Antineoplastic Agents; Biological Transport; Cell Line, Tumor; Cell Survival; Chitosan; Dendrimers; Drug Carriers; Fluorescein-5-isothiocyanate; Intracellular Space; Methotrexate; Mice; Nanoparticles; Platelet Aggregation | 2013 |
Self-assembled lysozyme/carboxymethylcellulose nanogels for delivery of methotrexate.
Topics: Carboxymethylcellulose Sodium; Cell Survival; Drug Delivery Systems; Drug Liberation; Dynamic Light Scattering; Endocytosis; Fluorescein-5-isothiocyanate; Hep G2 Cells; Humans; Hydrophobic and Hydrophilic Interactions; MCF-7 Cells; Methotrexate; Muramidase; Nanogels; Nephelometry and Turbidimetry; Particle Size; Polyethylene Glycols; Polyethyleneimine; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared | 2015 |
Nitrite-Responsive Hydrogel: Smart Drug Release Depending on the Severity of the Nitric Oxide-Related Disease.
Topics: Acrylic Resins; Animals; Arthritis, Experimental; Biocompatible Materials; Cell Survival; Cytokines; Drug Carriers; Drug Liberation; Elastic Modulus; Fluorescein-5-isothiocyanate; Hydrogels; Lipopolysaccharides; Macrophages; Male; Methotrexate; Mice; Nitric Oxide; Nitrites; Rats; RAW 264.7 Cells | 2020 |
Intraluminal Behavior of Various Transporter Substrates in the Rat Gastrointestinal Tract.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Carrier Proteins; Cephalexin; Dextrans; Fluorescein-5-isothiocyanate; Intestinal Absorption; Male; Methotrexate; Rats; Rats, Sprague-Dawley; Saquinavir | 2021 |
Layered double hydroxides - poloxamer 188 nanocomposites based on exfoliation reassembling for improved cellular uptake and controlled delivery of methotrexate.
Topics: Fluorescein-5-isothiocyanate; Hydroxides; Methotrexate; Nanocomposites; Poloxamer | 2023 |