flunitrazepam has been researched along with ro 20-1815 in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.63) | 18.7374 |
| 1990's | 7 (18.42) | 18.2507 |
| 2000's | 17 (44.74) | 29.6817 |
| 2010's | 13 (34.21) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Johnston, GA; Maddalena, DJ | 1 |
| Karplus, M; So, SS | 1 |
| Aubert, C; Cano, JP; Coassolo, P; Sumirtapura, YC | 1 |
| Cirimele, V; Kintz, P; Mangin, P; Staub, C | 1 |
| He, W; Parissis, N | 1 |
| Angermaier, L; Deinl, I; Franzelius, C; Machbert, G | 1 |
| Deitermann, D; Feeley, B; Kaleciak, K; Kronstrand, R; Lewis, D; Moore, C; Negrusz, A; Niedbala, RS | 1 |
| Brenneisen, R; ElSohly, MA; Feng, S; Salamone, SJ | 1 |
| Janicak, PG; Kern, JL; Le, NL; Levy, NA; Moore, CM; Negrusz, A; Palaparthy, R; Poiser, KR; Stockham, TL | 1 |
| Hinkel, KB; Janicak, PG; Moore, CM; Negrusz, A; Stockham, TL; Strong, MJ; Verma, M | 1 |
| Chen, CH; Cheng, WJ; Huang, TY; Li, JH; Lin, DL; Liu, C; Liu, RH; Tsay, WI; Wang, PH; Wu, TG | 1 |
| Tan, JY; Wu, YH; Xia, Y | 1 |
| Busto, UE; Gafni, I; Kaplan, HL; Sellers, EM; Tyndale, RF | 1 |
| Hayashi, T; Honda, K; Iino, M; Inoue, H; Masui, S; Matoba, R; Murai, T; Nakatome, M; Shinozuka, T; Tanaka, E; Terada, M; Watanabe, R | 1 |
| Druid, H; Kronstrand, R; Nyström, I; Strandberg, J | 1 |
| Elian, AA; Hackett, J | 1 |
| Briellmann, TA; Dussy, FE; Hamberg, C | 1 |
| Lord, HL; Pawliszyn, J; Rajabi, M; Safari, S | 1 |
| Chen, CH; Chen, YL; Lin, DL; Liu, RH; Yin, RM | 1 |
| Hsieh, YZ; Huang, CW; Jen, HP; Wang, RD | 1 |
| Katagi, M; Miki, A; Tsuchihashi, H; Zaitsu, K | 1 |
| Baud, FJ; Borron, SW; Bouchonnet, S; Debray, M; Declèves, X; Duarte, T; Megarbane, B; Milan, N; Perrin, B; Pirnay, S; Ricordel, I; Risède, P | 1 |
| Adachi, N; Ameno, K; Hishida, S; Kasuda, S; Kinoshita, H; Matsui, K; Minami, T; Nishiguchi, M; Ohtsu, N; Ouchi, H; Takahashi, M; Yoshida, S | 1 |
| Bassindale, A; Guthery, B; Morgan, GH; Pillinger, CT | 1 |
| Bai, HY; Chen, WS; Fuh, MR; Lin, TY; Melwanki, MB | 1 |
| Gunn, J; Kriger, S; Terrell, AR | 1 |
| Bai, HY; Chan, SA; Fuh, MR; Lin, SL | 1 |
| Kintz, P | 1 |
| Hatano, A; Makita, R; Nagao, M; Namera, A; Saruwatari, T; Shiraishi, H | 1 |
| Chen, YJ; Fuh, MR; Ho, YC; Lin, CC; Lu, YW; Tseng, MC | 1 |
| Castro, AL; Silvestre, A; Tarelho, S; Teixeira, HM | 1 |
| Bogdan, C; Kiss, B; Loghin, F; Pop, A | 1 |
| Dulaurent, S; Gaulier, JM; Lachâtre, G; Maublanc, J; Morichon, J | 1 |
| Daldrup, T; Lerch, O; Temme, O | 1 |
| Gonmori, K; Hasegawa, K; Minakata, K; Nozawa, H; Suzuki, O; Watanabe, K; Wurita, A; Yamagishi, I | 1 |
| Fuh, MR; Lin, SL; Liu, HY; Wu, YR | 1 |
| Bellaish, E; Koren, G; Maman, K | 1 |
| Liu, Y; Lu, J; Qiao, J; Qin, S; Wang, Y; Xin, G; Xu, D; Xu, Z; Zhang, W; Zhang, Y | 1 |
1 trial(s) available for flunitrazepam and ro 20-1815
| Article | Year |
|---|---|
GC-MS determination of flunitrazepam and its major metabolite in whole blood and plasma.
Topics: Anti-Anxiety Agents; Benzophenones; Flunitrazepam; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Substance Abuse Detection; Time Factors | 1999 |
37 other study(ies) available for flunitrazepam and ro 20-1815
| Article | Year |
|---|---|
Prediction of receptor properties and binding affinity of ligands to benzodiazepine/GABAA receptors using artificial neural networks.
Topics: Binding Sites; Ligands; Neural Networks, Computer; Predictive Value of Tests; Receptors, GABA-A; Structure-Activity Relationship | 1995 |
Genetic neural networks for quantitative structure-activity relationships: improvements and application of benzodiazepine affinity for benzodiazepine/GABAA receptors.
Topics: Algorithms; Benzodiazepines; Models, Genetic; Nerve Net; Protein Binding; Receptors, GABA-A; Structure-Activity Relationship | 1996 |
Determination of 7-amino-flunitrazepam (Ro 20-1815) and 7-amino-desmethylflunitrazepam (Ro 5-4650) in plasma by high-performance liquid chromatography and fluorescence detection.
Topics: Animals; Anti-Anxiety Agents; Chromatography, High Pressure Liquid; Flunitrazepam; Fluorescamine; Humans; Macaca mulatta; Spectrometry, Fluorescence | 1982 |
Testing human hair for flunitrazepam and 7-amino-flunitrazepam by GC/MS-NCI.
Topics: Flunitrazepam; GABA Modulators; Gas Chromatography-Mass Spectrometry; Hair; Humans; Substance Abuse Detection | 1997 |
Simultaneous determination of flunitrazepam and its metabolites in plasma and urine by HPLC/DAD after solid phase extraction.
Topics: Chromatography, High Pressure Liquid; Flunitrazepam; Humans; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet; Triazolam | 1997 |
Simple high-performance liquid chromatographic column-switching technique for the on-line immunoaffinity extraction and analysis of flunitrazepam and its main metabolites in urine.
Topics: Anti-Anxiety Agents; Centrifugation; Chromatography, High Pressure Liquid; Flunitrazepam; Humans; Hydrogen-Ion Concentration; Immunosorbent Techniques; Kinetics; Sensitivity and Specificity | 1997 |
Highly sensitive micro-plate enzyme immunoassay screening and NCI-GC-MS confirmation of flunitrazepam and its major metabolite 7-aminoflunitrazepam in hair.
Topics: Anti-Anxiety Agents; Autopsy; Benzodiazepines; Emergency Medical Services; Flunitrazepam; Gas Chromatography-Mass Spectrometry; Hair; Humans; Immunoenzyme Techniques; Rape; Reproducibility of Results; Sensitivity and Specificity; Suicide, Attempted | 1999 |
Elimination of 7-aminoflunitrazepam and flunitrazepam in urine after a single dose of Rohypnol.
Topics: Adult; Anti-Anxiety Agents; Female; Flunitrazepam; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Immunoassay; Male; Middle Aged; Rape; Time Factors | 2000 |
Deposition of 7-aminoflunitrazepam and flunitrazepam in hair after a single dose of Rohypnol.
Topics: Adult; Anti-Anxiety Agents; Female; Flunitrazepam; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Male; Middle Aged; Rape | 2001 |
Improved screen and confirmation test of 7-aminoflunitrazepam in urine specimens for monitoring flunitrazepam (Rohypnol) exposure.
Topics: Anti-Anxiety Agents; Cross Reactions; Dose-Response Relationship, Drug; Drug Monitoring; Efficiency; Enzyme-Linked Immunosorbent Assay; Flunitrazepam; Gas Chromatography-Mass Spectrometry; Humans; Mass Screening; Substance Abuse Detection | 2002 |
[Determination of 7-aminoflunitrazepam, the major metabolite of flunitrazepam in urine by high performance thin-layer chromatography].
Topics: Chromatography, Thin Layer; Flunitrazepam; Fluorescamine; Humans; Indicators and Reagents | 2002 |
The role of cytochrome P450 2C19 activity in flunitrazepam metabolism in vivo.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2C19; Female; Flunitrazepam; Humans; Male; Middle Aged; Mixed Function Oxygenases | 2003 |
Simultaneous determination of flunitrazepam and 7-aminoflunitrazepam in human serum by ion trap gas chromatography-tandem mass spectrometry.
Topics: Anti-Anxiety Agents; Flunitrazepam; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Molecular Structure; Sensitivity and Specificity | 2003 |
Screening for drugs of abuse in hair with ion spray LC-MS-MS.
Topics: Amphetamines; Anti-Anxiety Agents; Central Nervous System Stimulants; Chromatography, Liquid; Cocaine; Cotinine; Diazepam; Dopamine Uptake Inhibitors; Drug Overdose; Flunitrazepam; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Morphine; Morphine Derivatives; Narcotics; Nicotine; Nicotinic Agonists; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection | 2004 |
Extraction and analysis of flunitrazepam/7-aminoflunitrazepam in blood and urine by LC-PDA and GC-MS using butyl SPE columns.
Topics: Anti-Anxiety Agents; Chromatography, High Pressure Liquid; Flunitrazepam; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Nitrazepam | 2006 |
Quantification of benzodiazepines in whole blood and serum.
Topics: Anti-Anxiety Agents; Benzodiazepines; Chromatography, High Pressure Liquid; Flunitrazepam; Flurazepam; Forensic Toxicology; Humans; Mass Spectrometry; Midazolam; Molecular Structure; Serum | 2006 |
Development of immunoaffinity solid phase microextraction probes for analysis of sub ng/mL concentrations of 7-aminoflunitrazepam in urine.
Topics: Algorithms; Antibodies; Antibodies, Monoclonal; Buffers; Calibration; Chromatography, Affinity; Chromatography, Liquid; Flunitrazepam; Humans; Hypnotics and Sedatives; Immunochemistry; Immunoglobulin G; Indicators and Reagents; Oxazepam; Reproducibility of Results | 2006 |
Performance characteristics of 7-aminoflunitrazepam specific enzyme-linked immunosorbent assays.
Topics: Anti-Anxiety Agents; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Flunitrazepam; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Reproducibility of Results; Sensitivity and Specificity; Substance Abuse Detection; Workplace | 2005 |
Sweeping technique combined with micellar electrokinetic chromatography for the simultaneous determination of flunitrazepam and its major metabolites.
Topics: Anti-Anxiety Agents; Buffers; Calibration; Cetrimonium; Cetrimonium Compounds; Chromatography, Micellar Electrokinetic Capillary; Flunitrazepam; Humans; Hydrogen-Ion Concentration; Reproducibility of Results; Sensitivity and Specificity | 2006 |
Long-term stability of various drugs and metabolites in urine, and preventive measures against their decomposition with special attention to filtration sterilization.
Topics: Adolescent; Adult; Amphetamine; Central Nervous System Agents; Cocaine; Dopamine Uptake Inhibitors; Drug Stability; Estazolam; Female; Filtration; Flunitrazepam; Forensic Toxicology; Humans; Hydrolysis; Indicators and Reagents; Male; Methamphetamine; Middle Aged; Morphine Derivatives; Nitrazepam; Sodium Azide; Sterilization; Urine | 2008 |
Buprenorphine alters desmethylflunitrazepam disposition and flunitrazepam toxicity in rats.
Topics: Analgesics, Opioid; Animals; Biotransformation; Buprenorphine; Carbon Dioxide; Drug Interactions; Flunitrazepam; GABA Modulators; Hydrogen-Ion Concentration; Infusions, Intravenous; Male; Oxygen; Pulmonary Ventilation; Rats; Rats, Sprague-Dawley; Respiratory Insufficiency | 2008 |
A fatal case due to combined toxicity of psychotropic drugs.
Topics: Adult; Anti-Anxiety Agents; Brain Edema; Female; Flunitrazepam; Forensic Toxicology; Gastrointestinal Contents; Heart Arrest; Humans; Paroxetine; Pulmonary Edema; Selective Serotonin Reuptake Inhibitors; Trazodone | 2008 |
The detection of various opiates and benzodiazepines by comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry.
Topics: Acetamides; Benzodiazepines; Chromatography, Gas; Flunitrazepam; Fluoroacetates; Heroin; Humans; Linear Models; Models, Chemical; Opiate Alkaloids; Organosilicon Compounds; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Software; Solid Phase Extraction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substance Abuse Detection; Trifluoroacetic Acid; User-Computer Interface | 2009 |
Determination of 7-aminoflunitrazepam in urine by dispersive liquid-liquid microextraction with liquid chromatography-electrospray-tandem mass spectrometry.
Topics: Anti-Anxiety Agents; Chromatography, Liquid; Flunitrazepam; Spectrometry, Mass, Electrospray Ionization | 2009 |
Simultaneous determination and quantification of 12 benzodiazepines in serum or whole blood using UPLC/MS/MS.
Topics: Alprazolam; Benzodiazepines; Chlordiazepoxide; Chromatography, Liquid; Clonazepam; Flunitrazepam; Humans; Lorazepam; Midazolam; Nordazepam; Oxazepam; Reproducibility of Results; Tandem Mass Spectrometry | 2010 |
Characterization and evaluation of two-dimensional microfluidic chip-HPLC coupled to tandem mass spectrometry for quantitative analysis of 7-aminoflunitrazepam in human urine.
Topics: Anti-Anxiety Agents; Chromatography, High Pressure Liquid; Flunitrazepam; Humans; Microfluidic Analytical Techniques; Solid Phase Extraction; Tandem Mass Spectrometry | 2010 |
Segmental hair analysis can demonstrate external contamination in postmortem cases.
Topics: Adolescent; Adult; Aged, 80 and over; Anti-Anxiety Agents; Antipsychotic Agents; Bromazepam; Buprenorphine; Decontamination; Female; Flunitrazepam; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Hair; Humans; Male; Methylene Chloride; Morphine; N-Methyl-3,4-methylenedioxyamphetamine; Narcotics; Phenothiazines; Solvents; Sweating | 2012 |
Acute intoxication caused by overdose of flunitrazepam and triazolam: high concentration of metabolites detected at autopsy examination.
Topics: Anti-Anxiety Agents; Chromatography, High Pressure Liquid; Drug Overdose; Female; Flunitrazepam; Forensic Toxicology; Humans; Mass Spectrometry; Middle Aged; Triazolam | 2012 |
Nanoparticle-assisted MALDI-TOF MS combined with seed-layer surface preparation for quantification of small molecules.
Topics: Analytic Sample Preparation Methods; Chemical Fractionation; Feasibility Studies; Flunitrazepam; Gentisates; Limit of Detection; Linear Models; Magnetics; Molecular Weight; Morphine; Nanoparticles; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Surface Properties; Tandem Mass Spectrometry; Urinalysis | 2011 |
Simultaneous analysis of some club drugs in whole blood using solid phase extraction and gas chromatography-mass spectrometry.
Topics: Buprenorphine; Dextropropoxyphene; Flunitrazepam; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Ketamine; Limit of Detection; Methadone; Narcotics; Phencyclidine; Solid Phase Extraction | 2012 |
A rapid UPLC-MS/MS method for simultaneous determination of flunitrazepam, 7-aminoflunitrazepam, methadone and EDDP in human, rat and rabbit plasma.
Topics: Animals; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Female; Flunitrazepam; Humans; Male; Methadone; Pyrrolidines; Rabbits; Rats; Reproducibility of Results; Tandem Mass Spectrometry; Time Factors; Toxicity Tests | 2012 |
Identification and quantification of 35 psychotropic drugs and metabolites in hair by LC-MS/MS: application in forensic toxicology.
Topics: Chromatography, High Pressure Liquid; Clonazepam; Flunitrazepam; Forensic Toxicology; Hair; Humans; Limit of Detection; Psychotropic Drugs; Tandem Mass Spectrometry | 2015 |
Comprehensive automation of the solid phase extraction gas chromatographic mass spectrometric analysis (SPE-GC/MS) of opioids, cocaine, and metabolites from serum and other matrices.
Topics: Acetamides; Analgesics, Opioid; Automation; Cocaine; Codeine; Flunitrazepam; Fluoroacetates; Gas Chromatography-Mass Spectrometry; Humans; Limit of Detection; Methadone; Morphine; Morphine Derivatives; Reproducibility of Results; Robotics; Solid Phase Extraction; Substance Abuse Detection; Trimethylsilyl Compounds | 2014 |
Postmortem distribution of flunitrazepam and its metabolite 7-aminoflunitrazepam in body fluids and solid tissues in an autopsy case: Usefulness of bile for their detection.
Topics: Adipose Tissue; Aged; Autopsy; Bile; Body Fluids; Chromatography, Liquid; Female; Flunitrazepam; Homicide; Humans; Postmortem Changes; Tandem Mass Spectrometry; Time Factors | 2015 |
Quantification of 7-aminoflunitrazepam in human urine by polymeric monolith-based capillary liquid chromatography coupled to tandem mass spectrometry.
Topics: Chromatography, Liquid; Flunitrazepam; Humans; Liquid-Liquid Extraction; Methacrylates; Polymers; Tandem Mass Spectrometry | 2018 |
Withdrawn: Hair Analysis for Drug-Facilitated Crime: The Critical Role of Hair Growth Rate.
Topics: Crime; Female; Flunitrazepam; Forensic Toxicology; GABA Modulators; Hair; Hair Dyes; Humans; Male; Substance Abuse Detection | 2019 |
Characterization and tentative identification of new flunitrazepam metabolites in authentic human urine specimens using liquid chromatography-Q exactive-HF hybrid quadrupole-Orbitrap-mass spectrometry (LC-QE-HF-MS).
Topics: Chromatography, High Pressure Liquid; Flunitrazepam; Glucuronides; Humans; Hydroxylation; Metabolic Networks and Pathways; Metabolome; Oxidation-Reduction; Solid Phase Extraction; Tandem Mass Spectrometry | 2019 |