flunitrazepam has been researched along with propofol in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.03) | 18.7374 |
| 1990's | 21 (63.64) | 18.2507 |
| 2000's | 8 (24.24) | 29.6817 |
| 2010's | 3 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Prince, RJ; Simmonds, MA | 2 |
| Biggio, G; Concas, A; Gessa, GL; Peduto, VA; Santoro, G | 1 |
| D'Agostino, C; Fantera, A; Fegiz, A; Fioriti, A; Giancotti, C; Iannarone, C; Tellan, G | 1 |
| Biggio, G; Concas, A; Sanna, E; Santoro, G; Serra, M | 1 |
| Keller, I; Klasing, S; Madler, C; Schlund, M; Schwender, D | 1 |
| Amicucci, G; Ardigò, M; Candiani, A; Ferrazin, FR; Scipione, V; Zappa, S | 1 |
| Ardilouze, M; d'Athis, F; Dattez, C; Eledjam, JJ; Raulo, A; Rubio, C | 1 |
| Faber-Züllig, E; Klasing, S; Peter, K; Pöppel, E; Schwender, D | 1 |
| Faber-Züllig, E; Golling, W; Klasing, S; Peter, K; Pöppel, E; Schwender, D | 1 |
| Kaiser, A; Klasing, S; Peter, K; Pöppel, E; Schwender, D | 1 |
| Haessler, R; Klasing, S; Leppmeier, U; Peter, K; Rindfleisch, F; Schwender, D | 1 |
| Hecketsweiler, B; Kaeffer, N; Moore, N; Moritz, F; Oksenhendler, G; Papion, H; Petit, J; Winckler, C | 1 |
| Biggio, G; Ghiani, CA; Maciocco, E; Sanna, E; Serra, M; Tuligi, G | 1 |
| Bennett, PJ; Simmonds, MA | 1 |
| Simmonds, MA; Zhong, Y | 1 |
| Davies, PA; Hales, TG; Hanna, MC; Kirkness, EF | 1 |
| Haberstroh, J; Karzai, W; Müller, W; Priebe, HJ | 1 |
| Davies, M; Dunn, SM; Thuynsma, RP | 1 |
| Bruner, KR; Reynolds, JN | 1 |
| Fukuda, K; Ichinohe, T; Kaneko, Y; Kasahara, M; Mamiya, H; Noma, T | 1 |
| Ai, J; Kahnberg, P; Nielsen, M; Saederup, E; Squires, RF; Sterner, O; Witt, MR | 1 |
| Simmonds, MA; Sooksawate, T | 1 |
| Davies, PA; Hales, TG; Kirkness, EF | 1 |
| Asproni, B; Biggio, G; Busonero, F; Cerri, R; Maciocco, E; Mascia, MP; Pau, A; Sanna, E; Talani, G | 1 |
| Bujons, J; García, DA; Suñol, C; Vale, C | 1 |
| Bourgaux, C; Chanques, G; de La Coussaye, JE; Fabbro-Peray, P; Jaber, S; Lefrant, JY; Louart, G; Muller, L; Ripart, J | 1 |
| Betts, BA; Gill, N; Griffith, TN; Hall, AC; Humbert, DJ; Jenkins, A; Kelly, EW; Kotey, FO; Rowan, KC; Veneskey, KC; Watt, EE | 1 |
| Beynon, C; Hertle, DN; Neumann, JO; Sakowitz, OW; Sánchez-Porras, R; Santos, E; Unterberg, AW | 1 |
| Alderson, P; Lewis, SR; Schofield-Robinson, OJ; Smith, AF | 1 |
2 review(s) available for flunitrazepam and propofol
| Article | Year |
|---|---|
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
Propofol for the promotion of sleep in adults in the intensive care unit.
Topics: Adult; Dyssomnias; Flunitrazepam; Humans; Hypnotics and Sedatives; Intensive Care Units; Midazolam; Propofol; Randomized Controlled Trials as Topic; Sleep | 2018 |
7 trial(s) available for flunitrazepam and propofol
| Article | Year |
|---|---|
[Acoustic evoked potentials of medium latency and intraoperative wakefulness during anesthesia maintenance using propofol, isoflurane and flunitrazepam/fentanyl].
Topics: Adult; Anesthesia, General; Evoked Potentials, Auditory; Fentanyl; Flunitrazepam; Humans; Intraoperative Period; Isoflurane; Middle Aged; Propofol; Wakefulness | 1991 |
Motor signs of wakefulness during general anaesthesia with propofol, isoflurane and flunitrazepam/fentanyl and midlatency auditory evoked potentials.
Topics: Adult; Anesthesia, Epidural; Anesthesia, General; Cough; Evoked Potentials, Auditory; Female; Fentanyl; Flunitrazepam; Hemodynamics; Humans; Isoflurane; Middle Aged; Motor Neurons; Movement; Propofol; Statistics as Topic; Wakefulness | 1994 |
Effects of surgical stimulation on midlatency auditory evoked potentials during general anaesthesia with propofol/fentanyl, isoflurane/fentanyl and flunitrazepam/fentanyl.
Topics: Anesthesia, General; Anesthetics; Cardiac Surgical Procedures; Dermatologic Surgical Procedures; Evoked Potentials, Auditory; Fentanyl; Flunitrazepam; Hemodynamics; Humans; Isoflurane; Propofol; Sternum | 1994 |
Midlatency auditory evoked potentials and explicit and implicit memory in patients undergoing cardiac surgery.
Topics: Aged; Anesthesia, General; Awareness; Cardiac Surgical Procedures; Dose-Response Relationship, Drug; Evoked Potentials, Auditory, Brain Stem; Female; Fentanyl; Flunitrazepam; Humans; Intraoperative Period; Isoflurane; Male; Memory; Memory, Short-Term; Middle Aged; Monitoring, Intraoperative; Propofol | 1994 |
Anaesthesia for coronary artery bypass grafting: opioid-analgesia combined with either flunitrazepam, propofol or isoflurane.
Topics: Adult; Aged; Analgesia; Anesthesia, General; Blood Pressure; Coronary Artery Bypass; Electrocardiography; Evoked Potentials, Auditory; Female; Fentanyl; Flunitrazepam; Heart Rate; Hemodynamics; Humans; Isoflurane; Male; Middle Aged; Propofol; Prospective Studies; Reaction Time; Stroke Volume | 1993 |
Metabolic effects of propofol and flunitrazepam given for sedation after aortic surgery.
Topics: Aortic Aneurysm, Abdominal; Blood Pressure; Energy Metabolism; Flunitrazepam; Humans; Norepinephrine; Oxygen Consumption; Postoperative Care; Propofol; Time Factors | 1993 |
Pain following intravenous administration of sedative agents: a comparison of propofol with three benzodiazepines.
Topics: Adult; Analysis of Variance; Anesthetics, Intravenous; Anesthetics, Local; Anti-Anxiety Agents; Cross-Over Studies; Diazepam; Double-Blind Method; Drug Combinations; Female; Flunitrazepam; Humans; Injections, Intravenous; Lidocaine; Male; Midazolam; Pain; Pain Measurement; Propofol; Prospective Studies | 1998 |
24 other study(ies) available for flunitrazepam and propofol
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Temperature and anion dependence of allosteric interactions at the gamma-aminobutyric acid-benzodiazepine receptor.
Topics: Animals; Anions; Binding, Competitive; Brain Chemistry; Drug Interactions; Flunitrazepam; Male; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Wistar; Receptors, GABA-A; Temperature | 1992 |
Propofol potentiates the binding of [3H]flunitrazepam to the GABAA receptor complex.
Topics: Animals; Binding, Competitive; Drug Synergism; Flunitrazepam; Male; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Wistar; Receptors, GABA-A; Tritium | 1992 |
Biochemical and electrophysiologic evidence that propofol enhances GABAergic transmission in the rat brain.
Topics: Animals; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chloride Channels; Dose-Response Relationship, Drug; Flunitrazepam; gamma-Aminobutyric Acid; Male; Membrane Proteins; Propofol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Transmission | 1991 |
[Total intravenous anesthesia (TIVA): clinical comparison of 2 pharmacologic combinations: flunitrazepam-droperidol-fentanyl and propofol-droperidol-fentanyl].
Topics: Adult; Anesthesia, Intravenous; Droperidol; Female; Fentanyl; Flunitrazepam; Humans; Male; Middle Aged; Propofol | 1991 |
Neurochemical action of the general anaesthetic propofol on the chloride ion channel coupled with GABAA receptors.
Topics: Anesthetics; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Chlorides; Flunitrazepam; Male; Membrane Proteins; Muscimol; Propofol; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1991 |
[Sedation in spontaneous respiration in children during radiologic tests].
Topics: Child, Preschool; Conscious Sedation; Female; Flunitrazepam; Humans; Infant; Male; Propofol; Radiography; Respiration | 1990 |
[Sedation with high epidural anesthesia in digestive surgery. Propofol versus flunitrazepam-enflurane].
Topics: Anesthesia Recovery Period; Anesthesia, Epidural; Anesthetics; Digestive System Surgical Procedures; Enflurane; Flunitrazepam; Humans; Phenols; Propofol | 1987 |
Biochemical evaluations of the effects of loreclezole and propofol on the GABAA receptor in rat brain.
Topics: Anesthetics; Animals; Anticonvulsants; Brain; Bridged Bicyclo Compounds, Heterocyclic; Diazepam; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; Hypnotics and Sedatives; In Vitro Techniques; Male; Muscimol; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sulfur Radioisotopes; Triazoles; Tritium | 1996 |
The influence of membrane cholesterol on the GABAA receptor.
Topics: Animals; Brain; Cerebellum; Cerebral Cortex; Cholesterol; Dose-Response Relationship, Drug; Drug Interactions; Flunitrazepam; GABA Agents; Liposomes; Male; Muscimol; Pregnanolone; Propofol; Rats; Rats, Wistar; Receptors, GABA-A; Spinal Cord; Synaptic Membranes | 1996 |
Pharmacological characterisation of multiple components in the enhancement by pregnanolone and propofol of [3H]flunitrazepam binding to GABAA receptors.
Topics: Anesthetics, Intravenous; Animals; Bicuculline; Flunitrazepam; GABA Agonists; GABA Modulators; In Vitro Techniques; Male; Muscimol; Pregnanolone; Progesterone; Propofol; Rats; Rats, Wistar; Receptors, GABA-A; Synaptic Membranes | 1996 |
Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit.
Topics: Amino Acid Sequence; Anesthetics, Intravenous; Animals; Bicuculline; Brain; Cell Line; Consensus Sequence; DNA, Complementary; Flumazenil; Flunitrazepam; GABA Agents; gamma-Aminobutyric Acid; Humans; Molecular Sequence Data; Muscimol; Pentobarbital; Picrotoxin; Pregnanolone; Propofol; Rats; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Transfection | 1997 |
Rapid increase in inspired desflurane concentration does not elicit a hyperdynamic circulatory response in the pig.
Topics: Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Pressure; Catecholamines; Desflurane; Epinephrine; Female; Flunitrazepam; GABA Modulators; Heart Rate; Hemodynamics; Isoflurane; Male; Neuromuscular Nondepolarizing Agents; Preanesthetic Medication; Propofol; Swine; Time Factors; Vecuronium Bromide | 1997 |
Effects of propofol and pentobarbital on ligand binding to GABAA receptors suggest a similar mechanism of action.
Topics: Allosteric Site; Anesthetics, Intravenous; Animals; Azides; Benzodiazepines; Brain; Cattle; Flunitrazepam; GABA Agonists; In Vitro Techniques; Ligands; Membranes; Muscimol; Pentobarbital; Propofol; Receptors, GABA-A | 1998 |
Propofol modulation of [3H]flunitrazepam binding to GABAA receptors in guinea pig cerebral cortex.
Topics: Anesthetics, Intravenous; Animals; Anti-Anxiety Agents; Binding, Competitive; Cerebral Cortex; Drug Synergism; Flunitrazepam; GABA Modulators; Guinea Pigs; Male; Propofol; Receptors, GABA-A; Tritium | 1998 |
Honokiol and magnolol increase the number of [3H] muscimol binding sites three-fold in rat forebrain membranes in vitro using a filtration assay, by allosterically increasing the affinities of low-affinity sites.
Topics: Allosteric Regulation; Androstanes; Animals; Azasteroids; Binding Sites; Biphenyl Compounds; Cell Membrane; Central Nervous System Depressants; Cerebellum; Diflunisal; Drugs, Chinese Herbal; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Kinetics; Lignans; Muscimol; Picrotoxin; Propofol; Prosencephalon; Rats; Receptors, GABA-A; Tritium | 1999 |
Influence of membrane cholesterol on modulation of the GABA(A) receptor by neuroactive steroids and other potentiators.
Topics: Animals; Cell Membrane; Cholesterol; Dose-Response Relationship, Drug; Drug Synergism; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pentobarbital; Pregnanolone; Pregnenolone; Propofol; Rats; Rats, Wistar; Receptors, GABA-A | 2001 |
Evidence for the formation of functionally distinct alphabetagammaepsilon GABA(A) receptors.
Topics: Anesthetics, Intravenous; Cell Line; Drug Synergism; Electric Conductivity; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; Humans; Ion Channels; Propofol; Protein Isoforms; Receptors, GABA-A | 2001 |
Ethyl 2-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-4-imidazolecarboxylate is a novel positive modulator of GABAA receptors.
Topics: Animals; Binding, Competitive; Cell Membrane; Cerebral Cortex; Diazepam; Dose-Response Relationship, Drug; Etomidate; Female; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; Glycine; Humans; Hydrocarbons, Halogenated; Imidazoles; Male; Membrane Potentials; Oocytes; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glycine; Receptors, Serotonin, 5-HT3; Serotonin; Tritium; Xenopus laevis | 2005 |
Allosteric positive interaction of thymol with the GABAA receptor in primary cultures of mouse cortical neurons.
Topics: Anesthetics, Intravenous; Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Chloride Channels; Computer Simulation; Female; Flunitrazepam; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; L-Lactate Dehydrogenase; Mice; Models, Molecular; Models, Neurological; Muscimol; Neurons; Neurotoxins; Pregnancy; Propidium; Propofol; Receptors, GABA-A; Thymol | 2006 |
Impact of the use of propofol remifentanil goal-directed sedation adapted by nurses on the time to extubation in mechanically ventilated ICU patients: the experience of a French ICU.
Topics: Anesthetics, Intravenous; Flunitrazepam; France; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Intensive Care Units; Midazolam; Pain Measurement; Piperidines; Propofol; Remifentanil; Respiration, Artificial; Survival Rate; Treatment Outcome | 2008 |
Menthol shares general anesthetic activity and sites of action on the GABA(A) receptor with the intravenous agent, propofol.
Topics: Anesthetics, General; Anesthetics, Intravenous; Animals; Cyclohexanols; Flumazenil; Flunitrazepam; Menthol; Pentobarbital; Pregnanolone; Propofol; Receptors, GABA-A; Xenopus | 2008 |
Use of GABAergic sedatives after subarachnoid hemorrhage is associated with worse outcome-preliminary findings.
Topics: Adult; Aged; Brain; Conscious Sedation; Female; Flunitrazepam; GABA Modulators; Glasgow Coma Scale; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Propofol; Regeneration; Retrospective Studies; Subarachnoid Hemorrhage | 2016 |