flunitrazepam has been researched along with pk 11195 in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (30.77) | 18.7374 |
| 1990's | 19 (48.72) | 18.2507 |
| 2000's | 5 (12.82) | 29.6817 |
| 2010's | 2 (5.13) | 24.3611 |
| 2020's | 1 (2.56) | 2.80 |
| Authors | Studies |
|---|---|
| Bendinelli, S; Castellano, S; Cosconati, S; Costa, B; Da Pozzo, E; Da Settimo, F; Greco, G; Martini, C; Milite, C; Novellino, E; Pugliesi, I; Rizzetto, E; Sbardella, G; Stefancich, G; Taliani, S | 1 |
| Baglini, E; Barresi, E; Costa, B; Da Pozzo, E; Da Settimo, F; Martini, C; Robello, M; Salerno, S; Taliani, S | 1 |
| Gavish, M; Katz, Y; Weizman, A; Weizman, R | 1 |
| Brodie, MJ; Larkin, JG; Scobie, G; Thompson, GG | 1 |
| Amiri, Z; Burstein, O; Edoute, Y; Gavish, M; Katz, Y; Lochner, A; Weizman, R | 1 |
| De Luca, C; De Medici, D; Massotti, M | 1 |
| Becker, DP; Black, KL; Ikezaki, K; Payne, BA; Santori, EM; Smith, ML; Toga, AW | 1 |
| Calandra, RS; Calvo, DJ; Medina, JH; Ritta, MN | 1 |
| Gavish, M; Katz, Y | 1 |
| Gavish, M; Weizman, R | 1 |
| Black, KL; Ikezaki, K; Toga, AW | 1 |
| Fares, F; Gavish, M; Pick, CG; Weizman, A; Yanai, J | 1 |
| Arbilla, S; Langer, SZ | 1 |
| Ciliax, BJ; Mancini, WR; Olson, JM; Young, AB | 1 |
| Becker, D; Gavish, M; Tanne, Z; Weizman, R | 1 |
| Gavish, M; Okun, F; Weizman, A; Youdim, MB | 1 |
| Ciliax, BJ; McKeever, P; Penney, JB; Starosta-Rubinstein, S; Young, AB | 1 |
| Lafaille, F; Lal, S; Nair, NP; Quirion, R; Suranyi-Cadotte, B | 1 |
| Junck, L; Mancini, WR; Olson, JM; Penney, JB; Young, AB | 1 |
| Haumont, J; Lenfant, M; Zavala, F | 1 |
| Cascio, C; Guarneri, P; Guarneri, R; Papadopoulos, V; Piccoli, F | 1 |
| Niles, LP; Tenn, CC | 1 |
| Dalezios, Y; Matsokis, N; Valcana, T | 1 |
| Ruggieri, MR; Smyth, RJ; Uhlman, EJ | 1 |
| Beauchemin, V; Dennis, T; Lavoie, N | 1 |
| Alenfall, J; Batra, S | 1 |
| Amiri, Z; Bar-Ami, S; Fares, F; Gavish, M; Weizman, A | 1 |
| Giannaccini, G; Lucacchini, A; Martini, C; Piccolino, M; Strettoi, E | 1 |
| Nakamoto, Y; Shiotani, T; Watabe, S; Yoshii, M | 1 |
| Anzini, M; Basile, AS; Bruni, G; Cappelli, A; Giorgi, G; Langer, T; Romeo, MR; Vomero, S | 1 |
| Bessler, H; Caspi, B; Gavish, M; Rehavi, M; Weizman, A | 1 |
| Chaki, S; Nagamine, M; Nakazato, A; Ogawa, S; Okubo, T; Okuyama, S; Suzuki, Y; Tomisawa, K; Yoshikawa, R | 1 |
| Bono, F; Herbert, JM; Lamarche, I; Le Fur, G; Prabonnaud, V | 1 |
| Biggio, G; Busonero, F; Mascia, MP; Mostallino, MC; Pisu, MG; Talani, G | 1 |
| Biggio, G; Chiarelotto, G; Dall'Acqua, S; Ferlin, MG; Maciocco, E; Mascia, MP; Pisu, MG | 1 |
| Hajós, G; Kardos, J; Nyikos, L; Riedl, Z; Szárics, E | 1 |
| Lopes, DV; Mendonça-Silva, DL; Noël, F; Thibaut, JP | 1 |
| Ducroc, R; Lacapere, JJ; Ostuni, MA; Papadopoulos, V; Péranzi, G; Tonon, MC | 1 |
| Elbim, C; Fasseu, M; Issop, L; Lacapere, JJ; Ostuni, MA; Papadopoulos, V; Péranzi, G; Walker, F | 1 |
1 review(s) available for flunitrazepam and pk 11195
| Article | Year |
|---|---|
An update into the medicinal chemistry of translocator protein (TSPO) ligands.
Topics: Amino Acid Sequence; Animals; Anti-Anxiety Agents; Anticonvulsants; Apoptosis; Benzimidazoles; Benzodiazepines; Cell Proliferation; Diazepam; Humans; Imidazoles; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial ADP, ATP Translocases; Mitochondrial Membranes; Mitochondrial Permeability Transition Pore; Oxidative Stress; Protein Binding; Pyridines; Quinolines; Receptors, GABA; Structure-Activity Relationship; Voltage-Dependent Anion Channels | 2021 |
38 other study(ies) available for flunitrazepam and pk 11195
| Article | Year |
|---|---|
Synthesis and biological evaluation of 4-phenylquinazoline-2-carboxamides designed as a novel class of potent ligands of the translocator protein.
Topics: Animals; Binding, Competitive; Carrier Proteins; Cell Line, Tumor; Cell Survival; Inhibitory Concentration 50; Molecular Structure; Quinazolines; Rats; Receptors, GABA-A; Structure-Activity Relationship | 2012 |
Disulfiram and diethyldithiocarbamate are competitive inhibitors at the peripheral benzodiazepine receptor.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Disulfiram; Ditiocarb; Flunitrazepam; Isoquinolines; Kidney; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1992 |
Central and peripheral benzodiazepine receptors in rat brain and platelets: effects of treatment with diazepam and clobazam.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Blood Platelets; Brain; Clobazam; Diazepam; Drug Tolerance; Flunitrazepam; Injections, Intraperitoneal; Isoquinolines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1992 |
Testosterone and cyproterone acetate modulate peripheral but not central benzodiazepine receptors in rats.
Topics: Androgen Antagonists; Animals; Central Nervous System; Cyproterone; Cyproterone Acetate; Down-Regulation; Flunitrazepam; Hypophysectomy; Isoquinolines; Male; Peripheral Nerves; Rats; Rats, Inbred Strains; Receptors, GABA-A; Testosterone; Up-Regulation | 1991 |
Relative efficacies of benzodiazepine receptor agonists in affecting red nucleus electrical activity in rabbits.
Topics: Animals; Bicuculline; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Flunitrazepam; Imidazoles; Isoquinolines; Male; Pentylenetetrazole; Pyridazines; Pyridines; Rabbits; Receptors, GABA-A; Red Nucleus; Zolpidem | 1990 |
Three-dimensional comparison of peripheral benzodiazepine binding and histological findings in rat brain tumor.
Topics: Animals; Brain Neoplasms; Female; Flunitrazepam; Glioma; Isoquinolines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tomography, Emission-Computed | 1990 |
Peripheral-type benzodiazepine receptors are highly concentrated in mitochondrial membranes of rat testicular interstitial cells.
Topics: Animals; Benzodiazepinones; Binding, Competitive; Diazepam; Flunitrazepam; Intracellular Membranes; Isoquinolines; Kinetics; Leydig Cells; Male; Mitochondria; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1990 |
Laudanosine does not displace receptor-specific ligands from the benzodiazepinergic or muscarinic receptors.
Topics: Animals; Benzodiazepinones; Cerebral Cortex; Flunitrazepam; Isoquinolines; Kidney; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Muscarinic; Seizures | 1989 |
Effects of chronic chlorpromazine treatment on peripheral benzodiazepine binding sites in heart, kidney, and cerebral cortex of rats.
Topics: Animals; Cerebral Cortex; Chlorpromazine; Flunitrazepam; Isoquinolines; Kidney; Male; Myocardium; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1989 |
Imaging of brain tumors using peripheral benzodiazepine receptor ligands.
Topics: Animals; Autoradiography; Brain Neoplasms; Clonazepam; Female; Flunitrazepam; Glioma; Image Processing, Computer-Assisted; Isoquinolines; Ligands; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1989 |
Chronic phenobarbital administration affects GABA and benzodiazepine receptors in the brain and periphery.
Topics: Animals; Brain Chemistry; Flunitrazepam; Hippocampus; In Vitro Techniques; Isoquinolines; Kidney; Male; Membranes; Mice; Muscimol; Myocardium; Olfactory Bulb; Peripheral Nerves; Phenobarbital; Receptors, GABA-A | 1989 |
Imidazopyridines as a tool for the characterization of benzodiazepine receptors: a proposal for a pharmacological classification as omega receptor subtypes.
Topics: Animals; Brain Chemistry; Flunitrazepam; GABA-A Receptor Antagonists; Imidazoles; In Vitro Techniques; Isoquinolines; Kidney; Ligands; Pyridazines; Pyridines; Rats; Receptors, GABA-A; Spinal Cord; Terminology as Topic; Zolpidem | 1988 |
Presence of peripheral-type benzodiazepine binding sites on human erythrocyte membranes.
Topics: Benzodiazepinones; Clonazepam; Convulsants; Erythrocyte Membrane; Flunitrazepam; Humans; In Vitro Techniques; Isoquinolines; Kinetics; Monoamine Oxidase; Receptors, GABA-A | 1988 |
Effect of chronic haloperidol treatment on peripheral benzodiazepine binding sites in cerebral cortex of rats.
Topics: Animals; Cerebral Cortex; Flunitrazepam; Haloperidol; Heart; Isoquinolines; Male; Myocardium; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1988 |
Modulatory effects of thyroxine treatment on central and peripheral benzodiazepine receptors in the rat.
Topics: Animals; Cerebral Cortex; Flunitrazepam; Hyperthyroidism; Isoquinolines; Kidney; Male; Myocardium; Rats; Rats, Inbred Strains; Receptors, GABA-A; Testis; Thyroxine | 1986 |
Imaging of a glioma using peripheral benzodiazepine receptor ligands.
Topics: Adrenal Gland Neoplasms; Animals; Flunitrazepam; Glioma; Humans; Isoquinolines; Kidney; Mice; Mice, Nude; Neoplasm Transplantation; Neuroblastoma; Pheochromocytoma; Radionuclide Imaging; Rats; Rats, Inbred Strains; Receptors, GABA-A; Transplantation, Heterologous; Tritium | 1987 |
Coexistence of central and peripheral benzodiazepine binding sites in the human pineal gland.
Topics: Aged; Benzodiazepinones; Binding, Competitive; Cell Membrane; Clonazepam; Female; Flumazenil; Flunitrazepam; Humans; Isoquinolines; Male; Middle Aged; Pineal Gland; Receptors, GABA-A | 1987 |
Isoquinoline and peripheral-type benzodiazepine binding in gliomas: implications for diagnostic imaging.
Topics: Benzodiazepines; Benzodiazepinones; Brain Neoplasms; Cells, Cultured; Flunitrazepam; Glioma; Humans; Isoquinolines; Kinetics; Tomography, Emission-Computed | 1988 |
Interaction of benzodiazepines with mouse macrophages.
Topics: Animals; Anti-Anxiety Agents; Antibody Formation; Female; Flunitrazepam; In Vitro Techniques; Isoquinolines; Macrophages; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Receptors, GABA-A | 1984 |
gamma-Aminobutyric acid type A/benzodiazepine receptors regulate rat retina neurosteroidogenesis.
Topics: Animals; Flunitrazepam; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; In Vitro Techniques; Isoquinolines; Kinetics; Male; Neuroglia; Neurotransmitter Agents; Pregnenolone; Rats; Rats, Wistar; Receptors, GABA-A; Retina; Steroids; Synaptic Transmission | 1995 |
Central-type benzodiazepine receptors mediate the antidopaminergic effect of clonazepam and melatonin in 6-hydroxydopamine lesioned rats: involvement of a GABAergic mechanism.
Topics: Animals; Apomorphine; Behavior, Animal; Bicuculline; Clonazepam; Corpus Striatum; Dopamine Agonists; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Isoquinolines; Male; Melatonin; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1995 |
Interaction between [3H]flunitrazepam and [3H]GABA binding in the cerebellum of reeler mice.
Topics: Animals; Binding, Competitive; Carrier Proteins; Cerebellum; Flunitrazepam; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Isoquinolines; Membrane Proteins; Membrane Transport Proteins; Mice; Mice, Neurologic Mutants; Models, Neurological; Nerve Tissue Proteins; Organic Anion Transporters; Protein Binding; Receptors, GABA-A; Up-Regulation | 1995 |
Identification and characterization of a high-affinity peripheral-type benzodiazepine receptor in rabbit urinary bladder.
Topics: Animals; Flumazenil; Flunitrazepam; GABA-A Receptor Antagonists; Isoquinolines; Male; Muscle Contraction; Muscle, Smooth; Rabbits; Receptors, GABA-A; Urinary Bladder | 1994 |
Quantitative autoradiographic studies of the effects of bilateral olfactory bulbectomy in the rat brain: central- and peripheral-type benzodiazepine receptors.
Topics: Animals; Autoradiography; Behavior, Animal; Brain Chemistry; Flumazenil; Flunitrazepam; Isoquinolines; Male; Olfactory Bulb; Peripheral Nervous System; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1994 |
Characterization of peripheral benzodiazepine receptors in rat prostatic adenocarcinoma.
Topics: Adenocarcinoma; Animals; Benzodiazepinones; Binding, Competitive; Diazepam; Flunitrazepam; Isoquinolines; Male; Mesoporphyrins; Microsomes; Mitochondria; Neoplasm Transplantation; Prostatic Neoplasms; Rats; Receptors, GABA-A | 1994 |
Long-term testosterone or diethylstilbestrol treatment affects gamma-aminobutyric acid and central-type benzodiazepine receptors but not peripheral-type benzodiazepine receptors in the female rat brain.
Topics: Animals; Brain; Cerebellum; Diethylstilbestrol; Female; Flunitrazepam; In Vitro Techniques; Isoquinolines; Membranes; Muscimol; Parietal Lobe; Peripheral Nervous System; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Testosterone | 1993 |
The peripheral-type benzodiazepine receptor ligands [3H]Ro 5-4864 and [3H]PK 11195 bind to the retina of rabbit, but not of turtle.
Topics: Animals; Benzodiazepinones; Flunitrazepam; Isoquinolines; Ligands; Rabbits; Receptors, GABA-A; Retina; Tritium; Turtles | 1993 |
Peripheral-type benzodiazepine receptors in association with epileptic seizures in EL mice.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Binding Sites; Cell Fractionation; Convulsants; Epilepsy; Flunitrazepam; GABA-A Receptor Agonists; Isoquinolines; Membrane Proteins; Mice; Mice, Mutant Strains; Mitochondria; Pentylenetetrazole; Prosencephalon; Receptors, GABA-A; Tritium | 1996 |
Molecular basis of peripheral vs central benzodiazepine receptor selectivity in a new class of peripheral benzodiazepine receptor ligands related to alpidem.
Topics: Animals; Anti-Anxiety Agents; Binding, Competitive; Cerebral Cortex; Drug Design; Flunitrazepam; Imidazoles; Isoquinolines; Models, Molecular; Protein Conformation; Pyridines; Rats; Receptors, GABA-A; Structure-Activity Relationship | 1996 |
Significant inhibition of spontaneous IgA secretion by selective peripheral-type benzodiazepine receptor ligands.
Topics: Anti-Anxiety Agents; Antibody-Producing Cells; B-Lymphocytes; Clonazepam; Diazepam; Flunitrazepam; GABA-A Receptor Antagonists; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Isoquinolines; Lymphocyte Activation | 1997 |
Neuropharmacological profile of peripheral benzodiazepine receptor agonists, DAA1097 and DAA1106.
Topics: Acetamides; Anesthesia; Animals; Anti-Anxiety Agents; Benzodiazepinones; Brain; Buspirone; Cell Membrane; Diazepam; Exploratory Behavior; Flunitrazepam; GABA Modulators; GABA-A Receptor Agonists; Hexobarbital; Isoquinolines; Male; Mice; Mice, Inbred ICR; Mitochondria; Motor Activity; Phenyl Ethers | 1999 |
Peripheral benzodiazepine receptor agonists exhibit potent antiapoptotic activities.
Topics: Apoptosis; Benzodiazepinones; Clonazepam; Diazepam; Flunitrazepam; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Humans; Isoquinolines; Jurkat Cells; Kinetics; Ligands; Receptors, GABA-A; Transfection; Tumor Necrosis Factor-alpha; U937 Cells | 1999 |
Inhibition by miltirone of up-regulation of GABAA receptor alpha4 subunit mRNA by ethanol withdrawal in hippocampal neurons.
Topics: Animals; Binding, Competitive; Cells, Cultured; Central Nervous System Depressants; Cerebral Cortex; DNA, Complementary; Electrophysiology; Ethanol; Flunitrazepam; GABA Antagonists; Hippocampus; Isoquinolines; Male; Neurons; Oocytes; Patch-Clamp Techniques; Phenanthrenes; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA Probes; RNA, Messenger; Substance Withdrawal Syndrome; Tranquilizing Agents; Xenopus laevis | 2004 |
Novel anellated pyrazoloquinolin-3-ones: synthesis and in vitro BZR activity.
Topics: Animals; Brain; Female; Flunitrazepam; GABA Modulators; Humans; Isoquinolines; Male; Oocytes; Pyrazoles; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recombinant Proteins; Structure-Activity Relationship; Xenopus laevis | 2005 |
Interaction of novel condensed triazine derivatives with central and peripheral type benzodiazepine receptors: synthesis, in vitro pharmacology and modelling.
Topics: Animals; Binding, Competitive; Central Nervous System; Cerebral Cortex; Chromatography, Thin Layer; Flunitrazepam; GABA Modulators; In Vitro Techniques; Isoquinolines; Magnetic Resonance Spectroscopy; Male; Models, Molecular; Peripheral Nervous System; Point Mutation; Prosencephalon; Rats; Rats, Wistar; Receptors, GABA-A; Spectrophotometry, Infrared; Structure-Activity Relationship; Synaptic Membranes; Triazines | 2006 |
Characterization of two classes of benzodiazepine binding sites in Schistosoma mansoni.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Binding Sites; Clonazepam; Diazepam; Flunitrazepam; GABA Agonists; GABA Modulators; Inhibitory Concentration 50; Isoquinolines; Ligands; Male; Pyridines; Rats; Rats, Wistar; Receptors, GABA-A; Schistosoma mansoni; Synaptosomes; Temperature; Time Factors; Tritium; Zolpidem | 2007 |
Translocator protein (18 kDa) ligand PK 11195 induces transient mitochondrial Ca2+ release leading to transepithelial Cl- secretion in HT-29 human colon cancer cells.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Calcium; Cell Line, Tumor; Chlorides; Colonic Neoplasms; Cyclosporine; Enzyme Inhibitors; Flunitrazepam; GABA Modulators; Gene Expression Regulation, Neoplastic; Humans; Isoquinolines; Ligands; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Neoplasm Proteins; Nitrobenzoates; Receptors, GABA; Sodium-Potassium-Chloride Symporters | 2007 |
Overexpression of translocator protein in inflammatory bowel disease: potential diagnostic and treatment value.
Topics: Animals; Antineoplastic Agents; Benzodiazepinones; Carrier Proteins; Case-Control Studies; Colitis; Colon; Colonic Neoplasms; Cytokines; Dextran Sulfate; Enterocytes; Flunitrazepam; GABA Modulators; Humans; Hypolipidemic Agents; Immunoenzyme Techniques; Inflammatory Bowel Diseases; Isoquinolines; Male; Mitochondria; Rats; Rats, Wistar; Receptors, GABA; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2010 |