flunitrazepam has been researched along with pentobarbital in 94 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 39 (41.49) | 18.7374 |
| 1990's | 41 (43.62) | 18.2507 |
| 2000's | 12 (12.77) | 29.6817 |
| 2010's | 2 (2.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Andics, A; Gogolák, G; Huck, S; Stumpf, C | 2 |
| Dubois-Primo, J; Govaerts, M | 1 |
| Ho, IK; Yu, S | 1 |
| Prince, RJ; Simmonds, MA | 3 |
| Bowers, BJ; Wehner, JM | 1 |
| Baghdoyan, HA; Carlson, BX; Hawkins, RA; Mans, AM | 1 |
| Gallaher, EJ; Phillips, TJ | 1 |
| Allan, AM; Draski, LJ; Mayes, GG | 1 |
| Harris, RA; McQuilkin, SJ | 1 |
| Farb, DH; Friedman, L; Gibbs, TT; Roca, DJ; Rozenberg, I; Schiller, GD | 1 |
| Ben-Ari, Y; Rovira, C | 1 |
| Cano, J; Machado, A; Ruano, D; Vitorica, J | 1 |
| Costa, E; Paul, SM; Pritchett, DB; Puia, G; Purdy, RH; Santi, MR; Seeburg, PH; Vicini, S | 1 |
| Allan, AM; Harris, RA | 1 |
| Bristow, DR; Martin, IL | 1 |
| Mehta, AK; Ticku, MK | 1 |
| Barnett, A; Biggio, G; Corda, MG; Giorgi, O; Longoni, B; Montaldo, S; Ongini, E | 1 |
| Backus, KH; Kettenmann, H; Schachner, M | 1 |
| Kubicki, S; Meyer, C; Röhmel, J | 1 |
| Fanelli, RJ; Iadarola, MJ; McNamara, JO; Wilson, WA | 1 |
| Richter, JA; Yamamura, HI | 1 |
| Chweh, AY; Swinyard, EA; Ulloque, RA; Wolf, HH | 1 |
| Lee, RJ; Lomax, P; McCabe, RT; Olsen, RW; Wamsley, JK | 1 |
| Komiskey, HL; Meyers, MB | 1 |
| Cohen, RM; Havoundjian, H; Paul, SM; Skolnick, P | 1 |
| Sweetnam, PM; Tallman, JF | 1 |
| Ambrose, F; Barbaz, B; Bittiger, H; Iyengar, S; Neale, RF; Petrack, B; Rinehart, RK; Steel, DJ; Williams, M; Wood, PL | 1 |
| Beadle, DJ; Benson, JA; Lees, G; Neumann, R | 1 |
| Demura, H; Miyazaki, M; Mizobe, T; Okuda, C; Sawa, T; Tanaka, H | 1 |
| Grabow, L; Hein, A; Hendrikx, B; Schilling, E; Thiel, W | 2 |
| Kaneko, T; Ozaki, S; Yamatsu, K | 1 |
| Brendle, A; Erwin, CW; Linnoila, M | 1 |
| Kangas, L; Kanto, J; Leppänen, T; Pakkanen, A | 1 |
| Chiu, TH; Rosenberg, HC | 1 |
| Harris, RA; Rohde, BH | 1 |
| Corriol, J; Guillaume, V; Papy, JJ | 1 |
| Cardinali, DP; Lowenstein, PR | 1 |
| Borea, PA; Karobath, M; Supavilai, P | 1 |
| Asano, T; Ogasawara, N | 1 |
| Fanelli, RJ; McNamara, JO; Valdes, F | 1 |
| Horst, WD; Kuhar, MJ; Mashal, RD; Niehoff, DL; O'Brien, RA; Palacios, JM | 1 |
| Fanelli, RJ; McNamara, JO | 1 |
| Burch, TP; Thyagarajan, R; Ticku, MK | 1 |
| Kuhar, MJ; Mashal, RD; Niehoff, DL | 1 |
| Braestrup, C; Honoré, T; Nielsen, M | 1 |
| Barnard, EA; Sigel, E | 1 |
| Decobert, M; Depoortere, H; Honoré, L | 1 |
| Kangas, L; Kanto, J; Leppänen, T | 1 |
| Bormann, J; Feigenspan, A | 1 |
| Nabeshima, A; Saito, T; Takahata, N; Toki, S | 1 |
| Ho, IK; Ito, T; Suzuki, T; Wellman, SE | 3 |
| Bormann, J; Feigenspan, A; Wässle, H | 1 |
| Abeliovich, A; Harris, RA; McQuilkin, SJ; Paylor, R; Tonegawa, S; Wehner, JM | 1 |
| Dunwiddie, TV; Harris, RA; Klein, RL; Mascia, MP; McQuilkin, SJ; Proctor, WR; Whatley, V; Whiting, PJ | 1 |
| Harris, BD; Moody, EJ; Skolnick, P; Wong, G | 1 |
| Belelli, D; Chen, R; Lambert, JJ; Lan, NC; Peters, JA; Reyes, A | 1 |
| Baghdoyan, HA; Carlson, BX | 1 |
| Ho, IK; Kimura, T; Miyaoka, T; Saunders, PA; Tseng, YT | 1 |
| Hadingham, KL; Harkness, PC; Horne, AL; Kemp, JA; Whiting, P | 1 |
| Ho, IK; Miyaoka, T; Tseng, YT | 1 |
| Fuchs, K; Sieghart, W; Slany, A; Zezula, J | 1 |
| Biggio, G; Ghiani, CA; Maciocco, E; Sanna, E; Serra, M; Tuligi, G | 1 |
| Bain, C; Garrett, EM; Hadingham, KL; Heavens, RP; Sirinathsinghji, DJ; Wafford, KA; Whiting, PJ | 1 |
| Brozowski, SJ; Hadingham, KL; Harris, RA; Whatley, VJ; Whiting, PJ | 1 |
| Allan, AM; Engel, SR; Gandet, EA; Jackson, KA | 1 |
| Davies, PA; Hales, TG; Hanna, MC; Kirkness, EF | 1 |
| Belachew, S; Coucke, P; Goffin, F; Lefebvre, PP; Malgrange, B; Moonen, G; Rigo, JM; Van de Water, TR; Xhauflaire, G | 1 |
| Brozowski, S; Hadingham, K; Harris, RA; Mihic, SJ; Whiting, PJ | 1 |
| Simmonds, MA; Zhong, Y | 1 |
| Brozowski, S; Chuang, L; Hadingham, K; Harris, RA; Valenzuela, CF; Whiting, PJ | 1 |
| Davies, M; Dunn, SM; Thuynsma, RP | 1 |
| Dunwiddie, TV; Proctor, WR; Soldo, BL | 1 |
| Alkana, RL; Bolger, MB; Brinton, RD; Davies, DL; Finn, DA | 1 |
| Chistina Grobin, A; Devaud, LL; Inglefield, JR; Morrow, AL; Schwartz-Bloom, RD | 1 |
| Findlay, GS; Harris, RA; Harrison, NL; Ueno, S | 2 |
| France, CP; Gerak, LR; Harris, LS; Nader, MA; Patrick, GA; Winger, G; Woods, JH; Woolverton, WL | 1 |
| Baufreton, J; Bioulac, B; Dovero, S; Dufy, B; Garret, M; Taupignon, A | 1 |
| Alkana, RL; Bolger, MB; Davies, DL; McCauley, LD | 1 |
| Simmonds, MA; Sooksawate, T | 1 |
| Bäckström, T; Lundgren, P; Strömberg, J; Wang, M | 1 |
| Ariwodola, OJ; Weiner, JL | 1 |
| Asproni, B; Biggio, G; Busonero, F; Cerri, R; Maciocco, E; Mascia, MP; Pau, A; Sanna, E; Talani, G | 1 |
| Betts, BA; Gill, N; Griffith, TN; Hall, AC; Humbert, DJ; Jenkins, A; Kelly, EW; Kotey, FO; Rowan, KC; Veneskey, KC; Watt, EE | 1 |
| Gerak, LR | 1 |
| Contó, MB; de Carvalho, JG; Hipólide, DC; Venditti, MA | 1 |
1 review(s) available for flunitrazepam and pentobarbital
| Article | Year |
|---|---|
Drug effects on the EEG of various species of laboratory animals.
Topics: 5-Hydroxytryptophan; Amantadine; Animals; Antihypertensive Agents; Azabicyclo Compounds; Brain; Cats; Chlormethiazole; Clonidine; Diazepam; Electroencephalography; Flunitrazepam; Guanabenz; Guanfacine; Guanidines; Imidazoles; Male; Nitrazepam; Pentobarbital; Phenylacetates; Piperazines; Piracetam; Rats; Sodium Oxybate; Yohimbine | 1983 |
7 trial(s) available for flunitrazepam and pentobarbital
| Article | Year |
|---|---|
Double blind study of rectal flunitrazepam for pediatric premedication.
Topics: Adolescent; Anti-Anxiety Agents; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Female; Flunitrazepam; Humans; Infant; Male; Pentobarbital; Preanesthetic Medication; Rectum; Time Factors | 1979 |
[The 4 second sleep spindle periodicity].
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Cerebral Cortex; Double-Blind Method; Electroencephalography; Evoked Potentials; Flunitrazepam; Humans; Lorazepam; Methaqualone; Middle Aged; Pentobarbital; Periodicity; Random Allocation; Sleep Stages; Triazolam; Urea | 1986 |
[Equivalence of oral and intramuscular premedication. I. Oral versus intramuscular premedication].
Topics: Administration, Oral; Adolescent; Adult; Aged; Arousal; Droperidol; Drug Combinations; Female; Fentanyl; Flunitrazepam; Humans; Injections, Intramuscular; Male; Meperidine; Middle Aged; Pentobarbital; Preanesthetic Medication; Random Allocation | 1986 |
[Equivalence of oral and intramuscular premedication. II. Effect of various conventional premedication drugs].
Topics: Administration, Oral; Adolescent; Adult; Aged; Arousal; Attention; Droperidol; Drug Combinations; Female; Fentanyl; Flunitrazepam; Humans; Injections, Intramuscular; Male; Meperidine; Middle Aged; Pentobarbital; Preanesthetic Medication | 1986 |
Efficacy and side effects of flunitrazepam and pentobarbital in severely insomniac patients.
Topics: Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Female; Flunitrazepam; Humans; Male; Middle Aged; Motor Skills; Pentobarbital; Reaction Time; Sleep Initiation and Maintenance Disorders | 1982 |
Comparison of old and new types of premedications.
Topics: Administration, Oral; Anti-Anxiety Agents; Flunitrazepam; Humans; Injections, Intramuscular; Morphine; Pentobarbital; Preanesthetic Medication; Scopolamine | 1982 |
[Comparative study of the oral administration of flunitrazepam with oral pentobarbital and intramuscular administration of atropine and pethidine (meperidine) as premedication].
Topics: Administration, Oral; Adult; Atropine; Flunitrazepam; Humans; Injections, Intramuscular; Meperidine; Middle Aged; Pentobarbital; Preanesthetic Medication | 1984 |
86 other study(ies) available for flunitrazepam and pentobarbital
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
[Effect of combined application of halothane and some central depressants (author's transl)].
Topics: Anesthesia, Inhalation; Animals; Anti-Anxiety Agents; Diazepam; Drug Interactions; Flunitrazepam; Halothane; Male; Medazepam; Mice; Pentobarbital; Posture; Solvents | 1976 |
[Action of central depressants on the nitrous oxide anesthesia (author's transl)].
Topics: Anesthesia, Inhalation; Animals; Chlorpromazine; Dose-Response Relationship, Drug; Droperidol; Drug Interactions; Drug Synergism; Flunitrazepam; Male; Mice; Morphine; Nitrazepam; Nitrous Oxide; Pentobarbital; Tranquilizing Agents | 1975 |
Effects of acute pentobarbital administration on GABAA receptor-regulated chloride uptake in rat brain synaptoneurosomes.
Topics: Animals; Brain; Cerebellum; Cerebral Cortex; Chlorides; Flunitrazepam; Male; Muscimol; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes | 1992 |
5 beta-pregnan-3 beta-ol-20-one, a specific antagonist at the neurosteroid site of the GABAA receptor-complex.
Topics: Animals; Benzodiazepines; Binding, Competitive; Flunitrazepam; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Pentobarbital; Pregnanolone; Rats; Rats, Inbred Strains | 1992 |
Biochemical and behavioral effects of steroids on GABAA receptor function in long- and short-sleep mice.
Topics: Anesthetics; Animals; Behavior, Animal; Brain Chemistry; Chlorides; Desoxycorticosterone; Ethanol; Flunitrazepam; Male; Mice; Mice, Inbred Strains; Pentobarbital; Pregnanediones; Pregnenolone; Receptors, GABA-A; Sleep; Species Specificity; Steroids | 1992 |
Temperature and anion dependence of allosteric interactions at the gamma-aminobutyric acid-benzodiazepine receptor.
Topics: Animals; Anions; Binding, Competitive; Brain Chemistry; Drug Interactions; Flunitrazepam; Male; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Wistar; Receptors, GABA-A; Temperature | 1992 |
Propofol potentiates the binding of [3H]flunitrazepam to the GABAA receptor complex.
Topics: Animals; Binding, Competitive; Drug Synergism; Flunitrazepam; Male; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Wistar; Receptors, GABA-A; Tritium | 1992 |
Pentobarbital-enhanced [3H]flunitrazepam binding throughout the rat brain: an autoradiographic study.
Topics: Animals; Autoradiography; Behavior, Animal; Blood Pressure; Brain; Dose-Response Relationship, Drug; Evoked Potentials, Auditory; Evoked Potentials, Somatosensory; Flunitrazepam; Male; Pentobarbital; Posture; Rats; Receptors, GABA-A; Respiration | 1992 |
Locomotor responses to benzodiazepines, barbiturates and ethanol in diazepam-sensitive (DS) and -resistant (DR) mice.
Topics: Analysis of Variance; Animals; Diazepam; Dose-Response Relationship, Drug; Ethanol; Female; Flumazenil; Flunitrazepam; Male; Mice; Motor Activity; Pentobarbital; Phenobarbital | 1992 |
gamma-Aminobutyric acid-activated chloride channels in rats selectively bred for differential acute sensitivity to alcohol.
Topics: Alcohol Drinking; Animals; Chloride Channels; Diazepam; Female; Flunitrazepam; gamma-Aminobutyric Acid; Membrane Proteins; Muscimol; Pentobarbital; Phenobarbital; Phenotype; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Selection, Genetic | 1991 |
Factors affecting actions of ethanol on GABA-activated chloride channels.
Topics: Animals; Chlorides; Cold Temperature; Ethanol; Female; Flunitrazepam; gamma-Aminobutyric Acid; Ion Channels; Mice; Pentobarbital; Time Factors | 1990 |
gamma-Aminobutyric acidA receptor regulation in culture: altered allosteric interactions following prolonged exposure to benzodiazepines, barbiturates, and methylxanthines.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Allosteric Regulation; Animals; Barbital; Barbiturates; Brain; Caffeine; Cells, Cultured; Chick Embryo; Flumazenil; Flunitrazepam; Flurazepam; gamma-Aminobutyric Acid; Kinetics; Neurons; Pentobarbital; Receptors, GABA-A; Tetrodotoxin; Theophylline; Veratridine | 1990 |
Benzodiazepines do not potentiate GABA responses in neonatal hippocampal neurons.
Topics: Animals; Animals, Newborn; Drug Interactions; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Iontophoresis; Male; Midazolam; Neurons; Pentobarbital; Rats; Rats, Inbred Strains | 1991 |
Pharmacologic characterization of GABAA/benzodiazepine receptor in rat hippocampus during aging.
Topics: Aging; Animals; Binding Sites; Cerebellum; Cerebral Cortex; Culture Techniques; Drug Interactions; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Male; Muscimol; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1991 |
Neurosteroids act on recombinant human GABAA receptors.
Topics: Benzodiazepines; Cell Line, Transformed; Cell Membrane Permeability; Chlorides; Desoxycorticosterone; Electric Conductivity; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Kidney; Membrane Potentials; Pentobarbital; Pregnanolone; Receptors, GABA-A; Recombinant Proteins; Transfection | 1990 |
Sensitivity to ethanol hypnosis and modulation of chloride channels does not cosegregate with pentobarbital sensitivity in HS mice.
Topics: Animals; Arousal; Brain; Chloride Channels; Chlorides; Dose-Response Relationship, Drug; Drug Tolerance; Ethanol; Flunitrazepam; Ion Channels; Male; Membrane Proteins; Mice; Muscimol; Pentobarbital; Receptors, GABA-A; Sleep Stages | 1989 |
Solubilisation of the gamma-aminobutyric acid/benzodiazepine receptor from rat cerebellum: optimal preservation of the modulatory responses by natural brain lipids.
Topics: Animals; Cerebellum; Cholesterol Esters; Cholic Acids; Flunitrazepam; gamma-Aminobutyric Acid; Glycine max; Lipids; Male; Pentobarbital; Phospholipids; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A; Solubility; Solutions; Synaptic Membranes | 1987 |
Characteristics of flunitrazepam binding to intact primary cultured spinal cord neurons and its modulation by GABAergic drugs.
Topics: Animals; Benzodiazepines; Binding, Competitive; Carbolines; Cells, Cultured; Embryo, Mammalian; Etazolate; Etomidate; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Mice; Mice, Inbred C57BL; Muscimol; Neurons; Pentobarbital; Receptors, GABA-A; Spinal Cord | 1987 |
gamma-Aminobutyric acid and pentobarbital enhance 2-[3H]oxoquazepam binding to type I benzodiazepine recognition sites in rat and human brain.
Topics: Adult; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Brain; Chlorides; Drug Synergism; Female; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tritium | 1988 |
Effect of benzodiazepines and pentobarbital on the GABA-induced depolarization in cultured astrocytes.
Topics: Animals; Astrocytes; Benzodiazepines; Benzodiazepinones; Brain; Cells, Cultured; Flunitrazepam; gamma-Aminobutyric Acid; Membrane Potentials; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1988 |
Comparison of the effects of diphenylbarbituric acid, phenobarbital, pentobarbital and secobarbital on GABA-mediated inhibition and benzodiazepine binding.
Topics: Animals; Benzodiazepines; Electrophysiology; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Male; Pentobarbital; Phenobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Secobarbital; Time Factors | 1985 |
Effects of pentobarbital on t-[35S]butylbicyclophosphorothionate and [3H]flunitrazepam binding to membrane-bound and solubilized preparations from rat forebrain.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cholic Acids; Flunitrazepam; Kinetics; Pentobarbital; Rats; Receptors, GABA-A; Receptors, Neurotransmitter; Solubility; Temperature | 1985 |
Effect of picrotoxinin on benzodiazepine receptor binding.
Topics: Animals; Brain; Cerebellum; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Male; Membranes; Mice; Pentobarbital; Picrotoxin; Receptors, GABA-A; Sesterterpenes | 1985 |
Benzodiazepine/gamma-aminobutyric acid receptor deficit in the midbrain of the seizure-susceptible gerbil.
Topics: Animals; Bicuculline; Diazepam; Disease Models, Animal; Flunitrazepam; Gerbillinae; Mesencephalon; Muscimol; Pentobarbital; Receptors, GABA-A; Seizures | 1985 |
Aging: effect on the interaction of ethanol and pentobarbital with the benzodiazepine-GABA receptor-ionophore complex.
Topics: Aging; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Ethanol; Flunitrazepam; gamma-Aminobutyric Acid; Ionophores; Kinetics; Male; Pentobarbital; Rats; Rats, Inbred F344; Receptors, GABA-A; Temperature | 1985 |
Differential sensitivity of "central" and "peripheral" type benzodiazepine receptors to phospholipase A2.
Topics: Animals; Benzodiazepinones; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Cerebral Cortex; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Kidney; Male; Myocardium; Pentobarbital; Phospholipases; Phospholipases A; Phospholipases A2; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1986 |
Regional difference in brain benzodiazepine receptor carbohydrates.
Topics: Acetylglucosaminidase; Animals; Asparagine; Benzodiazepinones; Brain Chemistry; Carbohydrates; Electrophoresis, Polyacrylamide Gel; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Male; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Molecular Weight; Muscimol; Neuraminidase; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sialic Acids; Tritium | 1986 |
Benzodiazepine interactions with central thyroid-releasing hormone binding sites: characterization and physiological significance.
Topics: Amygdala; Animals; Benzodiazepines; Brain; Cerebral Cortex; Chlordiazepoxide; Corpus Striatum; Cyclic GMP; Flunitrazepam; Kinetics; Male; Membranes; Midazolam; Pentobarbital; Pyrazoles; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Thyrotropin-Releasing Hormone; Sleep; Thiazolidines; Thyrotropin; Thyrotropin-Releasing Hormone | 1986 |
Responses to GABA by isolated insect neuronal somata: pharmacology and modulation by a benzodiazepine and a barbiturate.
Topics: Animals; Chemical Phenomena; Chemistry; Flunitrazepam; gamma-Aminobutyric Acid; Ganglia; Grasshoppers; In Vitro Techniques; Pentobarbital; Receptors, GABA-A; Species Specificity; Vertebrates | 1987 |
Suppression of the pressor effect of centrally administered thyrotropin-releasing hormone under halothane, pentobarbital and flunitrazepam anaesthesia.
Topics: Animals; Blood Pressure; Depression, Chemical; Flunitrazepam; Halothane; Injections, Intraventricular; Male; Pentobarbital; Rats; Rats, Inbred Strains; Thyrotropin-Releasing Hormone | 1988 |
[Combined effect of flunitrazepam on activities of anesthetics and analgesics in mice and rats (author's transl)].
Topics: Analgesics; Anesthetics; Animals; Anti-Anxiety Agents; Droperidol; Drug Combinations; Drug Synergism; Fentanyl; Flunitrazepam; Halothane; Ketamine; Male; Mice; Morphine; Pentazocine; Pentobarbital; Rats; Rats, Inbred Strains; Thiopental | 1981 |
Comparison of the kinetics of [3H]diazepam and [3H]flunitrazepam binding to cortical synaptosomal membranes.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Cerebral Cortex; Diazepam; Filtration; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Male; Pentobarbital; Rats; Rats, Inbred Strains; Sodium Chloride; Synaptic Membranes | 1982 |
GABA and flunitrazepam binding to neuroblastoma cell membranes--effects of growth conditions, ethanol and pentobarbital.
Topics: Anti-Anxiety Agents; Binding, Competitive; Cell Line; Culture Media; Culture Techniques; Ethanol; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Kinetics; Neuroblastoma; Pentobarbital; Receptors, Cell Surface; Receptors, GABA-A | 1982 |
[A safe technic for anesthesia of the rabbit].
Topics: Anesthesia; Animals; Anti-Anxiety Agents; Flunitrazepam; Injections, Intramuscular; Injections, Subcutaneous; Pentobarbital; Preanesthetic Medication; Rabbits | 1982 |
Characterization of flunitrazepam and beta-carboline high affinity binding in bovine pineal gland.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Binding Sites; Carbolines; Cattle; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Indoles; Kinetics; Pentobarbital; Pineal Gland; Rats; Species Specificity | 1983 |
Differential modulation of etazolate or pentobarbital enhanced [3H] muscimol binding by benzodiazepine agonists and inverse agonists.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Binding, Competitive; Carbolines; Cell Membrane; Cerebral Cortex; Convulsants; Etazolate; Flumazenil; Flunitrazepam; Kinetics; Muscimol; Nicotinic Acids; Oxazoles; Pentobarbital; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Chloride-dependent stimulation of GABA and benzodiazepine receptor binding by pentobarbital.
Topics: Animals; Brain; Cattle; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Pentobarbital; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A | 1981 |
Barbiturate and GABA receptors coupled to benzodiazepine receptors in rat hippocampal formation: a radiohistochemical study.
Topics: Animals; Autoradiography; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Histocytochemistry; Male; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter | 1981 |
Binding of a radiolabeled triazolopyridazine to a subtype of benzodiazepine receptor in the rat cerebellum.
Topics: Animals; Anions; Cerebellum; Flunitrazepam; gamma-Aminobutyric Acid; Male; Pentobarbital; Pyrazoles; Pyridazines; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, GABA-A | 1982 |
Kindled seizures result in decreased responsiveness of benzodiazepine receptors to gamma-aminobutyric acid (GABA).
Topics: Animals; Flunitrazepam; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Seizures; Sodium Chloride | 1983 |
Group-selective reagent modification of the benzodiazepine-gamma-aminobutyric acid receptor-ionophore complex reveals that low-affinity gamma-aminobutyric acid receptors stimulate benzodiazepine binding.
Topics: Animals; Benzodiazepines; Cell Membrane; Cerebellum; Cerebral Cortex; Diazepam; Diazonium Compounds; Diethyl Pyrocarbonate; Flunitrazepam; Hippocampus; Male; Muscimol; Pentobarbital; Rats; Receptors, Cell Surface; Receptors, GABA-A; Sulfanilic Acids | 1983 |
Benzodiazepine receptors: preferential stimulation of Type 1 receptors by pentobarbital.
Topics: Animals; Cerebellum; Cerebral Cortex; Flunitrazepam; In Vitro Techniques; Male; Pentobarbital; Pyridazines; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Barbiturate shift as a tool for determination of efficacy of benzodiazepine-receptor ligands.
Topics: Animals; Benzodiazepines; Brain; Carbolines; Convulsants; Flunitrazepam; In Vitro Techniques; Ionophores; Ligands; Pentobarbital; Rats; Receptors, Cell Surface; Receptors, GABA-A; Sodium Chloride; Synaptic Membranes | 1984 |
A gamma-aminobutyric acid/benzodiazepine receptor complex from bovine cerebral cortex. Improved purification with preservation of regulatory sites and their interactions.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cerebral Cortex; Cholic Acids; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Methods; Muscimol; Pentobarbital; Receptors, Cell Surface; Receptors, GABA-A; Solubility | 1984 |
Differential pharmacology of GABAA and GABAC receptors on rat retinal bipolar cells.
Topics: Animals; Bicuculline; Binding Sites; Cells, Cultured; Chickens; Chloride Channels; Dose-Response Relationship, Drug; Flunitrazepam; GABA Antagonists; GABA-A Receptor Antagonists; Hexachlorocyclohexane; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Pyridazines; Rats; Rats, Wistar; Receptors, GABA; Receptors, GABA-A; Retina; Sesterterpenes; Signal Transduction | 1994 |
[Changes in GABAA/benzodiazepine receptor complex function in the pentobarbital-dependent rat. II: Strain differences between Lewis and Wistar-Kyoto rats].
Topics: Animals; Bicuculline; Brain; Chlorine; Ethanol; Female; Flunitrazepam; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Lew; Rats, Inbred WKY; Receptors, GABA-A; Substance-Related Disorders | 1995 |
Changes in [3H]flunitrazepam binding in the brain of rats made tolerant to and dependent upon pentobarbital.
Topics: Animals; Brain; Drug Tolerance; Flunitrazepam; Injections, Intraventricular; Male; Pentobarbital; Radioligand Assay; Rats; Rats, Sprague-Dawley; Substance-Related Disorders; Tissue Distribution; Tritium | 1995 |
Pharmacology of GABA receptor Cl- channels in rat retinal bipolar cells.
Topics: Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Chloride Channels; Flunitrazepam; gamma-Aminobutyric Acid; Ion Channels; Membrane Potentials; Membrane Proteins; Neurons; Pentobarbital; Photoreceptor Cells; Picrotoxin; Pregnanediones; Rats; Receptors, GABA-A; Sesterterpenes; Strychnine | 1993 |
Mutant mice lacking the gamma isoform of protein kinase C show decreased behavioral actions of ethanol and altered function of gamma-aminobutyrate type A receptors.
Topics: Animals; Base Sequence; Body Temperature; Cerebellum; Cerebral Cortex; Chlorides; DNA Primers; Ethanol; Female; Flunitrazepam; Isoenzymes; Male; Mice; Mice, Mutant Strains; Molecular Sequence Data; Pentobarbital; Polymerase Chain Reaction; Posture; Protein Kinase C; Receptors, GABA-A; Reflex | 1995 |
Ethanol increases GABAA responses in cells stably transfected with receptor subunits.
Topics: Animals; Cattle; Cells, Cultured; Chloride Channels; Chlorides; Dose-Response Relationship, Drug; Ethanol; Flunitrazepam; Mice; Pentobarbital; Receptors, GABA-A; Transfection | 1995 |
Different subunit requirements for volatile and nonvolatile anesthetics at gamma-aminobutyric acid type A receptors.
Topics: Anesthetics; Binding Sites; Cell Line; Flunitrazepam; Halothane; Humans; Isoflurane; Pentobarbital; Pregnanediones; Receptors, GABA-A | 1995 |
Cloning and functional expression of a Drosophila gamma-aminobutyric acid receptor.
Topics: Amino Acid Sequence; Animals; Base Sequence; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cloning, Molecular; Convulsants; DNA Primers; DNA, Complementary; Drosophila melanogaster; Female; Flunitrazepam; gamma-Aminobutyric Acid; Gene Expression; Macromolecular Substances; Molecular Sequence Data; Muscimol; Oocytes; Pentobarbital; Picrotoxin; Polymerase Chain Reaction; Receptors, GABA; Receptors, GABA-A; Transcription, Genetic; Xenopus laevis | 1994 |
Pentobarbital differentially enhances the affinity of [3H]flunitrazepam binding across brain regions.
Topics: Animals; Binding Sites; Brain; Flunitrazepam; Male; Pentobarbital; Rats; Receptors, GABA; Receptors, GABA-A | 1994 |
Binding characteristics of [3H]flunitrazepam in pentobarbital-withdrawal rats.
Topics: Animals; Cell Membrane; Cerebral Ventricles; Chlorides; Cholic Acids; Flunitrazepam; Frontal Lobe; Infusions, Parenteral; Kinetics; Male; Pentobarbital; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Substance Withdrawal Syndrome; Tritium | 1994 |
The influence of the gamma 2L subunit on the modulation of responses to GABAA receptor activation.
Topics: Anesthetics; Animals; Fibroblasts; Flunitrazepam; gamma-Aminobutyric Acid; L Cells; Mice; Pentobarbital; Pregnanediones; Receptors, GABA-A; Recombinant Proteins; Transfection | 1993 |
Region-specific changes of GABAA receptors by tolerance to and dependence upon pentobarbital.
Topics: Animals; Body Temperature; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Corpus Striatum; Drug Tolerance; Flunitrazepam; Frontal Lobe; In Vitro Techniques; Injections, Intraventricular; Male; Muscimol; Pentobarbital; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Substance-Related Disorders; Sulfur Radioisotopes; Synaptic Membranes | 1993 |
Allosteric modulation of [3H]flunitrazepam binding to recombinant GABAA receptors.
Topics: Allosteric Regulation; Animals; Binding, Competitive; Cell Line; Cerebellum; Dose-Response Relationship, Drug; Etomidate; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Kidney; Pentobarbital; Radioligand Assay; Rats; Receptors, GABA-A | 1995 |
Biochemical evaluations of the effects of loreclezole and propofol on the GABAA receptor in rat brain.
Topics: Anesthetics; Animals; Anticonvulsants; Brain; Bridged Bicyclo Compounds, Heterocyclic; Diazepam; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; Hypnotics and Sedatives; In Vitro Techniques; Male; Muscimol; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sulfur Radioisotopes; Triazoles; Tritium | 1996 |
Cloning of cDNAs encoding the human gamma-aminobutyric acid type A receptor alpha 6 subunit and characterization of the pharmacology of alpha 6-containing receptors.
Topics: Amino Acid Sequence; Animals; Antisense Elements (Genetics); Autoradiography; Base Sequence; Cerebellar Cortex; Cloning, Molecular; DNA Primers; DNA, Complementary; Female; Flunitrazepam; gamma-Aminobutyric Acid; Humans; In Situ Hybridization; Kinetics; L Cells; Ligands; Macromolecular Substances; Membrane Potentials; Mice; Molecular Sequence Data; Oocytes; Pentobarbital; Polymerase Chain Reaction; Pregnanolone; Rats; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Transfection; Xenopus laevis | 1996 |
An autoradiographic study of [3H]flunitrazepam binding sites in the brain of rat made tolerant to and dependent on pentobarbital.
Topics: Animals; Autoradiography; Binding Sites; Brain; Drug Tolerance; Flunitrazepam; Male; Pentobarbital; Rats; Rats, Sprague-Dawley; Tissue Distribution | 1996 |
Microtubule depolymerization inhibits ethanol-induced enhancement of GABAA responses in stably transfected cells.
Topics: Animals; Cattle; Cell Line; Chlorides; Colchicine; Ethanol; Flunitrazepam; Humans; Mice; Microtubules; Muscimol; Pentobarbital; Polymers; Receptor Aggregation; Receptors, GABA-A; Transfection | 1996 |
Effect of in vivo administration of anesthetics on GABAA receptor function.
Topics: Anesthesia; Anesthetics; Anesthetics, Inhalation; Animals; Brain; Carbon Dioxide; Chlorides; Ethanol; Flunitrazepam; GABA Modulators; Methoxyflurane; Mice; Mice, Inbred ICR; Pentobarbital; Receptors, GABA | 1996 |
Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit.
Topics: Amino Acid Sequence; Anesthetics, Intravenous; Animals; Bicuculline; Brain; Cell Line; Consensus Sequence; DNA, Complementary; Flumazenil; Flunitrazepam; GABA Agents; gamma-Aminobutyric Acid; Humans; Molecular Sequence Data; Muscimol; Pentobarbital; Picrotoxin; Pregnanolone; Propofol; Rats; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Transfection | 1997 |
Diazepam-insensitive GABAA receptors on postnatal spiral ganglion neurones in culture.
Topics: Animals; Animals, Newborn; Baclofen; Bicuculline; Carbolines; Cells, Cultured; Convulsants; Diazepam; Flunitrazepam; gamma-Aminobutyric Acid; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Spiral Ganglion; Zinc | 1997 |
Ethanol, flunitrazepam, and pentobarbital modulation of GABAA receptors expressed in mammalian cells and Xenopus oocytes.
Topics: Animals; Cattle; Cell Line, Transformed; Chloride Channels; Dose-Response Relationship, Drug; Ethanol; Flunitrazepam; Gene Expression; Humans; Mice; Muscimol; Oocytes; Pentobarbital; Protein Processing, Post-Translational; Receptors, GABA-A; Xenopus | 1997 |
Interactions between loreclezole, chlormethiazole and pentobarbitone at GABA(A) receptors: functional and binding studies.
Topics: Animals; Anticonvulsants; Bicuculline; Chlormethiazole; Flunitrazepam; In Vitro Techniques; Male; Medulla Oblongata; Pentobarbital; Rats; Rats, Wistar; Receptors, GABA-A; Triazoles | 1997 |
Adaptation of gamma-aminobutyric acid type A receptors to alcohol exposure: studies with stably transfected cells.
Topics: Animals; Cells, Cultured; Drug Tolerance; Ethanol; Flunitrazepam; Humans; Mice; Muscimol; Pentobarbital; Pregnanolone; Protein Kinase C; Receptors, GABA-A; Transfection; Zinc | 1998 |
Effects of propofol and pentobarbital on ligand binding to GABAA receptors suggest a similar mechanism of action.
Topics: Allosteric Site; Anesthetics, Intravenous; Animals; Azides; Benzodiazepines; Brain; Cattle; Flunitrazepam; GABA Agonists; In Vitro Techniques; Ligands; Membranes; Muscimol; Pentobarbital; Propofol; Receptors, GABA-A | 1998 |
Ethanol selectively enhances the hyperpolarizing component of neocortical neuronal responses to locally applied GABA.
Topics: Animals; Central Nervous System Depressants; Electrophysiology; Ethanol; Flunitrazepam; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Male; Membrane Potentials; Neocortex; Neurons; Pentobarbital; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synapses | 1998 |
Autoradiographic study of [3H]flunitrazepam binding sites in the subnuclei of the thalamus of rats rendered tolerant to and dependent on pentobarbital.
Topics: Animals; Autoradiography; Binding Sites; Drug Tolerance; Flunitrazepam; GABA Modulators; Hypnotics and Sedatives; Male; Pentobarbital; Radionuclide Imaging; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Substance-Related Disorders; Thalamic Nuclei; Tissue Distribution; Tritium | 1998 |
In vivo and in vitro hyperbaric studies in mice suggest novel sites of action for ethanol.
Topics: Allosteric Regulation; Analysis of Variance; Animals; Diazepam; Ethanol; Flunitrazepam; GABA Modulators; Hyperbaric Oxygenation; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Pentobarbital; Pregnanolone; Receptors, GABA-A | 1999 |
Fluorescence imaging of GABAA receptor-mediated intracellular [Cl-] in P19-N cells reveals unique pharmacological properties.
Topics: Animals; Central Nervous System Depressants; Chlorides; Diazepam; DNA Primers; Ethanol; Flunitrazepam; Fluorescent Dyes; GABA Agonists; GABA Modulators; Gene Expression; Mice; Muscimol; Neoplastic Stem Cells; Neuroglia; Pentobarbital; Pregnanolone; Quinolinium Compounds; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tritium | 1999 |
Allosteric modulation in spontaneously active mutant gamma-aminobutyric acid(A) receptors [corrected].
Topics: Allosteric Regulation; Amino Acid Substitution; Animals; Bicuculline; Cells, Cultured; Female; Flunitrazepam; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Mutagenesis, Site-Directed; Oocytes; Pentobarbital; Picrotoxin; Protein Structure, Tertiary; Receptors, GABA-A; Steroids; Xenopus laevis | 2000 |
Behavioral effects of flunitrazepam: reinforcing and discriminative stimulus effects in rhesus monkeys and prevention of withdrawal signs in pentobarbital-dependent rats.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Discrimination Learning; Female; Flunitrazepam; GABA Modulators; Macaca mulatta; Male; Pentobarbital; Reinforcement, Psychology; Substance Withdrawal Syndrome; Substance-Related Disorders | 2001 |
Allosteric modulation in spontaneously active mutant gamma-aminobutyric acidA receptors.
Topics: Allosteric Regulation; Animals; Bicuculline; Electric Conductivity; Female; Flunitrazepam; GABA Antagonists; GABA Modulators; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Pregnanolone; Protein Isoforms; Receptors, GABA-A; Xenopus laevis | 2001 |
Activation of GABA(A) receptors in subthalamic neurons in vitro: properties of native receptors and inhibition mechanisms.
Topics: Animals; Bicarbonates; Bicuculline; Chlorides; Diazepam; Electrophysiology; Flunitrazepam; GABA Agonists; GABA Antagonists; GABA Modulators; Membrane Potentials; Muscimol; Neural Inhibition; Neurons; Organ Culture Techniques; Pentobarbital; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Sesterterpenes; Subthalamic Nucleus | 2001 |
Pressure-sensitive and -insensitive coupling in gamma-aminobutyric acid(A) receptors.
Topics: Animals; Atmospheric Pressure; Chlorides; Chlorine; Flunitrazepam; GABA Modulators; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Pentobarbital; Pregnanolone; Radioisotopes; Receptors, GABA-A; Synaptosomes | 2001 |
Influence of membrane cholesterol on modulation of the GABA(A) receptor by neuroactive steroids and other potentiators.
Topics: Animals; Cell Membrane; Cholesterol; Dose-Response Relationship, Drug; Drug Synergism; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pentobarbital; Pregnanolone; Pregnenolone; Propofol; Rats; Rats, Wistar; Receptors, GABA-A | 2001 |
Allopregnanolone-stimulated GABA-mediated chloride ion flux is inhibited by 3beta-hydroxy-5alpha-pregnan-20-one (isoallopregnanolone).
Topics: Animals; Cerebral Cortex; Chlorides; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Osmolar Concentration; Pentobarbital; Pregnanolone; Rats; Rats, Wistar | 2003 |
Ethanol potentiation of GABAergic synaptic transmission may be self-limiting: role of presynaptic GABA(B) receptors.
Topics: Animals; Autoreceptors; Baclofen; Bicuculline; Central Nervous System Depressants; Electric Stimulation; Electrophysiology; Ethanol; Flunitrazepam; GABA-A Receptor Antagonists; Hippocampus; In Vitro Techniques; Male; Morpholines; Neural Inhibition; Pentobarbital; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission | 2004 |
Ethyl 2-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-4-imidazolecarboxylate is a novel positive modulator of GABAA receptors.
Topics: Animals; Binding, Competitive; Cell Membrane; Cerebral Cortex; Diazepam; Dose-Response Relationship, Drug; Etomidate; Female; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; Glycine; Humans; Hydrocarbons, Halogenated; Imidazoles; Male; Membrane Potentials; Oocytes; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glycine; Receptors, Serotonin, 5-HT3; Serotonin; Tritium; Xenopus laevis | 2005 |
Menthol shares general anesthetic activity and sites of action on the GABA(A) receptor with the intravenous agent, propofol.
Topics: Anesthetics, General; Anesthetics, Intravenous; Animals; Cyclohexanols; Flumazenil; Flunitrazepam; Menthol; Pentobarbital; Pregnanolone; Propofol; Receptors, GABA-A; Xenopus | 2008 |
Selective changes in sensitivity to benzodiazepines, and not other positive GABA(A) modulators, in rats receiving flunitrazepam chronically.
Topics: Animals; Benzodiazepines; Binding Sites; Dose-Response Relationship, Drug; Drug Tolerance; Flunitrazepam; Ketamine; Male; Midazolam; Morphine; Pentobarbital; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reinforcement Schedule; Substance-Related Disorders | 2009 |
Rats with different thresholds for DMCM-induced clonic convulsions differ in the sleep-time of diazepam and [(3)H]-Ro 15-4513 binding.
Topics: Animals; Anticonvulsants; Autoradiography; Azides; Benzodiazepines; Carbolines; Convulsants; Diazepam; Differential Threshold; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Flunitrazepam; GABA Modulators; Male; Pentobarbital; Rats; Rats, Wistar; Reaction Time; Seizures; Sleep; Statistics, Nonparametric; Tritium | 2012 |