Compounds > flunitrazepam

flunitrazepam and omeprazole

flunitrazepam has been researched along with omeprazole in 7 studies

Research

Studies (7)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (14.29)	18.2507
2000's	5 (71.43)	29.6817
2010's	1 (14.29)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Li, Y; Li, YH; Wang, YH; Yang, L; Yang, SL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Klíma, J; Macek, J; Ptácek, P	1
Kilicarslan, T; Sellers, EM	1
Greenblatt, DJ; Hesse, LM; Shader, RI; Venkatakrishnan, K; von Moltke, LL	1

Other Studies

7 other study(ies) available for flunitrazepam and omeprazole

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism. Bioorganic & medicinal chemistry letters, 2005, Sep-15, Volume: 15, Issue:18 Topics: Computational Biology; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Molecular Structure; Principal Component Analysis; Pyrrolizidine Alkaloids; Quantitative Structure-Activity Relationship; Reproducibility of Results; Substrate Specificity; Venlafaxine Hydrochloride	2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Determination of omeprazole in human plasma by high-performance liquid chromatography. Journal of chromatography. B, Biomedical sciences and applications, 1997, Feb-07, Volume: 689, Issue:1 Topics: Chromatography, High Pressure Liquid; Drug Stability; Flunitrazepam; Humans; Indicators and Reagents; Omeprazole; Pentanols; Reproducibility of Results; Sensitivity and Specificity; Solvents; Toluene	1997
Lack of interaction of buprenorphine with flunitrazepam metabolism. The American journal of psychiatry, 2000, Volume: 157, Issue:7 Topics: Buprenorphine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dealkylation; DNA, Complementary; Drug Interactions; Flunitrazepam; Humans; Microsomes, Liver; Mixed Function Oxygenases; Omeprazole	2000
CYP3A4 is the major CYP isoform mediating the in vitro hydroxylation and demethylation of flunitrazepam. Drug metabolism and disposition: the biological fate of chemicals, 2001, Volume: 29, Issue:2 Topics: Anti-Anxiety Agents; Benzoflavones; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Flunitrazepam; Humans; Hydroxylation; Isoenzymes; Ketoconazole; Kinetics; Methylation; Microsomes, Liver; Mixed Function Oxygenases; Omeprazole; Quinidine; Ritonavir; Sulfaphenazole; Transfection	2001