flunitrazepam has been researched along with morphine in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (22.22) | 18.7374 |
| 1990's | 14 (38.89) | 18.2507 |
| 2000's | 9 (25.00) | 29.6817 |
| 2010's | 5 (13.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Heermann, J | 1 |
| Andics, A; Gogolák, G; Huck, S; Stumpf, C | 1 |
| Gibert-Rahola, J; Maldonado, R; Micó, JA; Valverde, O | 2 |
| Calvo, P; Fernandez-Lopez, A; Gomez, T; Soria, C | 1 |
| Chesley, S; Greenblatt, DJ; Lopez, F; Miller, LG; Schatzki, A; Shader, RI; Thompson, ML | 1 |
| Breimer, DD; de Boer, AG; van Hoogdalem, E | 1 |
| Back, DJ; Eagling, VA; Macleod, R; Sim, SM | 1 |
| Hofmann, M; Kleemann, PP | 1 |
| Daubländer, M; Lipp, M | 1 |
| Tephly, TR; Thomassin, J | 1 |
| Hole, K; Rosland, JH | 1 |
| Bjørneboe, A; Bjørneboe, GE; Bugge, A; Drevon, CA; Gjerde, H; Mørland, J | 1 |
| Laqua, F; Prager, J; Tolksdorf, W | 1 |
| Gibert-Rahola, J; Leonsegui, I; Maldonado, R; Micó, JA; Saavedra, MC | 1 |
| Kaneko, T; Ozaki, S; Yamatsu, K | 1 |
| Kangas, L; Kanto, J; Leppänen, T; Pakkanen, A | 1 |
| Dimai, W; Gattiker, R | 1 |
| Lamarche, J | 1 |
| Boldt, J; Hempelmann, G; Hofmann, HC; Thiel, A; Wulf, K; Zickmann, B | 1 |
| Chugani, HT; Engel, J; Rocha, L; Tatsukawa, K | 1 |
| Ackermann, RF; Engel, J; Rocha, L | 1 |
| Finley, B; Franklin, R; King, C | 1 |
| Baudry, F; Douceron, H; Hassnaoui, S; Marc, B; Vaquero, P; Zerrouki, L | 1 |
| Baud, FJ; Borron, SW; Monier, C; Risède, P | 1 |
| Druid, H; Kronstrand, R; Nyström, I; Strandberg, J | 1 |
| Loscalzo, LM; Marder, M; Paladini, AC; Wasowski, C | 1 |
| Gerak, LR | 1 |
| Kintz, P | 1 |
| Chen, YJ; Fuh, MR; Ho, YC; Lin, CC; Lu, YW; Tseng, MC | 1 |
| Daldrup, T; Lerch, O; Temme, O | 1 |
2 review(s) available for flunitrazepam and morphine
| Article | Year |
|---|---|
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
Pharmacokinetics of rectal drug administration, Part I. General considerations and clinical applications of centrally acting drugs.
Topics: Administration, Rectal; Antiemetics; Atropine; Carbamazepine; Clonazepam; Delayed-Action Preparations; Diazepam; Flunitrazepam; Humans; Hydromorphone; Intestinal Absorption; Methadone; Methohexital; Midazolam; Morphine; Pharmacokinetics; Phenobarbital; Valproic Acid | 1991 |
2 trial(s) available for flunitrazepam and morphine
| Article | Year |
|---|---|
[Oral premedication before ENT interventions with local anesthesia. Effect profile of midazolam, flunitrazepam and morphine sulfate in comparison with placebo].
Topics: Administration, Oral; Adult; Aged; Anesthesia, Local; Clinical Trials as Topic; Double-Blind Method; Flunitrazepam; Humans; Midazolam; Middle Aged; Morphine; Preanesthetic Medication; Random Allocation; Tonsillectomy | 1988 |
Comparison of old and new types of premedications.
Topics: Administration, Oral; Anti-Anxiety Agents; Flunitrazepam; Humans; Injections, Intramuscular; Morphine; Pentobarbital; Preanesthetic Medication; Scopolamine | 1982 |
32 other study(ies) available for flunitrazepam and morphine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
[Flunitrazepam with anterograde amnesia and reduction of blood pressure before local anaesthesia without intubation in 3000 ENT operations (author's transl)].
Topics: Administration, Oral; Anesthesia, Local; Anti-Anxiety Agents; Atropine; Blood Pressure; Flunitrazepam; Humans; Injections, Intravenous; Morphine; Otorhinolaryngologic Diseases; Preanesthetic Medication; Sensation | 1979 |
[Action of central depressants on the nitrous oxide anesthesia (author's transl)].
Topics: Anesthesia, Inhalation; Animals; Chlorpromazine; Dose-Response Relationship, Drug; Droperidol; Drug Interactions; Drug Synergism; Flunitrazepam; Male; Mice; Morphine; Nitrazepam; Nitrous Oxide; Pentobarbital; Tranquilizing Agents | 1975 |
Changes in benzodiazepine-receptor activity modify morphine withdrawal syndrome in mice.
Topics: Animals; Azides; Behavior, Animal; Benzodiazepines; Benzodiazepinones; Flumazenil; Flunitrazepam; Male; Mice; Morphine; Receptors, GABA-A; Substance Withdrawal Syndrome | 1992 |
[3H]-flunitrazepam binding after morphine treatment and under abstinence syndrome.
Topics: Animals; Autoradiography; Brain; Flunitrazepam; Hippocampus; Male; Morphine; Organ Specificity; Pyramidal Tracts; Rats; Rats, Inbred Strains; Receptors, GABA-A; Reference Values; Substance Withdrawal Syndrome; Tritium | 1991 |
Chronic morphine administration augments benzodiazepine binding and GABAA receptor function.
Topics: Animals; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Chlorine; Flunitrazepam; In Vitro Techniques; Ion Channels; Male; Mice; Morphine; Muscimol; Naltrexone; Radioisotopes; Receptors, GABA-A; Sulfur Radioisotopes | 1990 |
In vitro inhibition studies of the glucuronidation of 3'-azido-3'-deoxythymidine catalysed by human liver UDP-glucuronosyl transferase.
Topics: Acquired Immunodeficiency Syndrome; Diazepam; Didanosine; Dose-Response Relationship, Drug; Flunitrazepam; Glucuronosyltransferase; Humans; Kinetics; Microsomes, Liver; Morphine; Naproxen; Zidovudine | 1992 |
[Free fatty acids as an indicator of preoperative stress and effects of premedication with flunitrazepam, morphine and promethazine on blood fatty acid level].
Topics: Adolescent; Adult; Anxiety; Face; Fatty Acids, Nonesterified; Female; Flunitrazepam; Humans; Male; Maxilla; Middle Aged; Morphine; Preanesthetic Medication; Promethazine; Sex Factors; Stress, Physiological | 1991 |
[Premedication and analgesic dose procedures in dental medicine].
Topics: Anesthesia, Dental; Anesthesia, Local; Buprenorphine; Clorazepate Dipotassium; Diazepam; Flunitrazepam; Humans; Lorazepam; Meperidine; Midazolam; Morphine; Oxazepam; Pain; Pentazocine; Pirinitramide; Preanesthetic Medication | 1991 |
Photoaffinity labeling of rat liver microsomal morphine UDP-glucuronosyltransferase by [3H]flunitrazepam.
Topics: Affinity Labels; Animals; Female; Flunitrazepam; Glucuronosyltransferase; Microsomes, Liver; Molecular Weight; Morphine; Rats; Rats, Inbred Strains; Ultraviolet Rays | 1990 |
1,4-Benzodiazepines antagonize opiate-induced antinociception in mice.
Topics: Analgesia; Animals; Buprenorphine; Diazepam; Dose-Response Relationship, Drug; Fentanyl; Flunitrazepam; Male; Mice; Midazolam; Morphine; Narcotic Antagonists; Psychomotor Performance | 1990 |
A retrospective study of drugged driving in Norway.
Topics: Adolescent; Adult; Age Factors; Amphetamine; Automobile Driving; Diazepam; Dronabinol; Ethanol; Female; Flunitrazepam; Humans; Male; Meprobamate; Middle Aged; Morphine; Norway; Retrospective Studies; Substance-Related Disorders; Toluene | 1987 |
Comparative study in mice of flunitrazepam vs. diazepam on morphine withdrawal syndrome.
Topics: Animals; Behavior, Animal; Diazepam; Flunitrazepam; Male; Mice; Mice, Inbred Strains; Morphine; Morphine Dependence; Naloxone; Substance Withdrawal Syndrome | 1988 |
[Combined effect of flunitrazepam on activities of anesthetics and analgesics in mice and rats (author's transl)].
Topics: Analgesics; Anesthetics; Animals; Anti-Anxiety Agents; Droperidol; Drug Combinations; Drug Synergism; Fentanyl; Flunitrazepam; Halothane; Ketamine; Male; Mice; Morphine; Pentazocine; Pentobarbital; Rats; Rats, Inbred Strains; Thiopental | 1981 |
[Intravenous narcotics in cardiac surgery].
Topics: Anesthesia, Intravenous; Blood Pressure; Cardiac Surgical Procedures; Fentanyl; Flunitrazepam; Heart Rate; Humans; Morphine; Narcotics; Preanesthetic Medication | 1981 |
[Proposal of dispensary pharmacists to improve current practices of substitution. Self-substitution and prescribed substitution].
Topics: Buprenorphine; Codeine; Family Practice; Flunitrazepam; Heroin Dependence; Humans; Morphine; Pharmacists; Self Medication; Substance-Related Disorders | 1994 |
[Topographic changes in cerebral electric activity after premedication with flunitrazepam].
Topics: Administration, Oral; Adult; Aged; Anesthesia, General; Brain Mapping; Cerebral Cortex; Coronary Artery Bypass; Delta Rhythm; Dose-Response Relationship, Drug; Electroencephalography; Flunitrazepam; Humans; Injections, Intramuscular; Male; Middle Aged; Morphine; Preanesthetic Medication; Signal Processing, Computer-Assisted; Theta Rhythm | 1994 |
Benzodiazepine receptor binding following chronic treatment with naloxone, morphine and met-enkephalin in normal rats.
Topics: Animals; Brain; Densitometry; Enkephalin, Methionine; Flunitrazepam; Injections, Intraperitoneal; Injections, Intraventricular; Male; Morphine; Naloxone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1993 |
Study of the mechanisms involved in behavioral changes induced by flunitrazepam in morphine withdrawal.
Topics: Animals; Behavior, Animal; Dogs; Dose-Response Relationship, Drug; Flunitrazepam; Male; Mice; Mice, Inbred Strains; Morphine; Prazosin; Propranolol; Substance Withdrawal Syndrome | 1995 |
Effects of chronic morphine pretreatment on amygdaloid kindling development, postictal seizure and suppression and benzodiazepine receptor binding in rats.
Topics: Amygdala; Animals; Autoradiography; Brain; Flunitrazepam; GABA Modulators; Hippocampus; Kindling, Neurologic; Male; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures | 1996 |
The glucuronidation of morphine by dog liver microsomes: identification of morphine-6-O-glucuronide.
Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Enzyme Inhibitors; Flunitrazepam; Glucuronosyltransferase; Humans; Male; Microsomes, Liver; Morphine; Morphine Derivatives | 2000 |
Sexual assault under benzodiazepine submission in a Paris suburb.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Benzodiazepines; Cocaine; Dronabinol; Estazolam; Female; Flunitrazepam; Humans; Hypnotics and Sedatives; Immunoassay; Lorazepam; Male; Morphine; Narcotics; Nitrazepam; Paris; Rape; Retrospective Studies; Substance-Related Disorders; Temazepam; Time Factors; Triazolam | 2000 |
Flunitrazepam variably alters morphine, buprenorphine, and methadone lethality in the rat.
Topics: Animals; Anti-Anxiety Agents; Buprenorphine; Drug Interactions; Flunitrazepam; Injections, Intraperitoneal; Injections, Intravenous; Lethal Dose 50; Male; Methadone; Morphine; Narcotics; Rats; Rats, Sprague-Dawley | 2002 |
Screening for drugs of abuse in hair with ion spray LC-MS-MS.
Topics: Amphetamines; Anti-Anxiety Agents; Central Nervous System Stimulants; Chromatography, Liquid; Cocaine; Cotinine; Diazepam; Dopamine Uptake Inhibitors; Drug Overdose; Flunitrazepam; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Morphine; Morphine Derivatives; Narcotics; Nicotine; Nicotinic Agonists; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection | 2004 |
Opioid receptors are involved in the sedative and antinociceptive effects of hesperidin as well as in its potentiation with benzodiazepines.
Topics: Acetic Acid; Alprazolam; Analgesics; Animals; Behavior, Animal; Benzodiazepines; Dose-Response Relationship, Drug; Drug Synergism; Flunitrazepam; Hesperidin; Hypnotics and Sedatives; Injections, Intraperitoneal; Male; Mice; Morphine; Motor Activity; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Receptors, Opioid | 2008 |
Selective changes in sensitivity to benzodiazepines, and not other positive GABA(A) modulators, in rats receiving flunitrazepam chronically.
Topics: Animals; Benzodiazepines; Binding Sites; Dose-Response Relationship, Drug; Drug Tolerance; Flunitrazepam; Ketamine; Male; Midazolam; Morphine; Pentobarbital; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reinforcement Schedule; Substance-Related Disorders | 2009 |
Segmental hair analysis can demonstrate external contamination in postmortem cases.
Topics: Adolescent; Adult; Aged, 80 and over; Anti-Anxiety Agents; Antipsychotic Agents; Bromazepam; Buprenorphine; Decontamination; Female; Flunitrazepam; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Hair; Humans; Male; Methylene Chloride; Morphine; N-Methyl-3,4-methylenedioxyamphetamine; Narcotics; Phenothiazines; Solvents; Sweating | 2012 |
Nanoparticle-assisted MALDI-TOF MS combined with seed-layer surface preparation for quantification of small molecules.
Topics: Analytic Sample Preparation Methods; Chemical Fractionation; Feasibility Studies; Flunitrazepam; Gentisates; Limit of Detection; Linear Models; Magnetics; Molecular Weight; Morphine; Nanoparticles; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Surface Properties; Tandem Mass Spectrometry; Urinalysis | 2011 |
Comprehensive automation of the solid phase extraction gas chromatographic mass spectrometric analysis (SPE-GC/MS) of opioids, cocaine, and metabolites from serum and other matrices.
Topics: Acetamides; Analgesics, Opioid; Automation; Cocaine; Codeine; Flunitrazepam; Fluoroacetates; Gas Chromatography-Mass Spectrometry; Humans; Limit of Detection; Methadone; Morphine; Morphine Derivatives; Reproducibility of Results; Robotics; Solid Phase Extraction; Substance Abuse Detection; Trimethylsilyl Compounds | 2014 |