flunitrazepam has been researched along with methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (51.85) | 18.7374 |
| 1990's | 10 (37.04) | 18.2507 |
| 2000's | 2 (7.41) | 29.6817 |
| 2010's | 1 (3.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cook, JM; Cox, ED; Diaz-Arauzo, H; Harris, B; Huang, Q; Ma, C; McKernan, R; Reddy, MS; Skolnick, P | 1 |
| Cook, JM; Dayer, CA; He, X; Huang, Q; Liu, R; Ma, C; McKernan, R; Wenger, GR; Yu, S | 1 |
| Buck, KJ; Harris, RA; McQuilkin, SJ | 1 |
| Ewert, M; Kettenmann, H; Kleingoor, C; Seeburg, PH; von Blankenfeld, G | 1 |
| Adojaan, A; Allikmets, L; Harro, J; Kiivet, RA; Rägo, L | 1 |
| Buck, KJ; Harris, RA | 2 |
| Ewert, M; Kettenmann, H; Pritchett, DB; Seeburg, PH; Sontheimer, H; von Blankenfeld, G; Ymer, S | 1 |
| Evoniuk, G; Skolnick, P | 2 |
| Costa, E; Mienville, JM; Vicini, S | 1 |
| Evoniuk, G; Moody, EJ; Skolnick, P | 1 |
| Cox, DH; Guidotti, A; Santi, MR | 1 |
| Harro, J; Kiivet, RA; Pŏld, M; Rägo, L | 1 |
| Sieghart, W | 1 |
| Maksay, G; Simonyi, M | 1 |
| Alho, H; Costa, E; Mienville, JM; Santi, MR; Vaccarino, FM; Vicini, S | 1 |
| Braestrup, C; Honoré, T; Nielsen, M | 2 |
| Braestrup, C; Tacke, U | 1 |
| Borea, PA; Karobath, M; Supavilai, P | 1 |
| Braestrup, C; Honoré, T; Jensen, LH; Nielsen, M; Petersen, EN | 1 |
| Ferenci, P; Herneth, A; Püspök, A; Steindl, P | 1 |
| Belachew, S; Coucke, P; Goffin, F; Lefebvre, PP; Malgrange, B; Moonen, G; Rigo, JM; Van de Water, TR; Xhauflaire, G | 1 |
| Bowery, BJ; Dawson, GR; Easter, A; Seabrook, GR | 1 |
| Bostwick, R; Chen, T; Huston, J; Knappenberger, K; Liu, J; Norris, T; Wood, M | 1 |
| Contó, MB; de Carvalho, JG; Hipólide, DC; Venditti, MA | 1 |
1 review(s) available for flunitrazepam and methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate
| Article | Year |
|---|---|
Benzodiazepine receptor ligands with negative efficacy: chloride channel coupling.
Topics: Animals; Barbiturates; Brain; Carbolines; Chlorides; Flunitrazepam; Humans; Ion Channels; Ligands; Membranes; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
26 other study(ies) available for flunitrazepam and methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate
| Article | Year |
|---|---|
Synthesis and evaluation of analogues of the partial agonist 6-(propyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester (6-PBC) and the full agonist 6-(benzyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester (Zk 93423)
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Binding, Competitive; Carbolines; Cell Line; Cerebral Cortex; Drug Design; GABA Agonists; Humans; Male; Mice; Muscle Relaxation; Rats; Receptors, GABA-A; Recombinant Proteins; Seizures; Structure-Activity Relationship | 1998 |
Pharmacophore/receptor models for GABA(A)/BzR subtypes (alpha1beta3gamma2, alpha5beta3gamma2, and alpha6beta3gamma2) via a comprehensive ligand-mapping approach.
Topics: Animals; Benzodiazepines; Carbolines; Cell Line; Columbidae; Conditioning, Operant; Crystallography, X-Ray; Humans; Indoles; Ligands; Male; Models, Molecular; Pyrimidines; Quinolones; Radioligand Assay; Receptors, GABA-A; Saimiri; Stereoisomerism; Structure-Activity Relationship | 2000 |
Modulation of gamma-aminobutyric acidA receptor-operated chloride channels by benzodiazepine inverse agonists is related to genetic differences in ethanol withdrawal seizure severity.
Topics: Animals; Benzodiazepines; Carbolines; Chloride Channels; Chlorides; Convulsants; Ethanol; Flunitrazepam; Genetic Predisposition to Disease; Male; Membrane Proteins; Mice; Mice, Inbred Strains; Muscimol; Receptors, GABA-A; Seizures; Substance Withdrawal Syndrome | 1991 |
Inverse but not full benzodiazepine agonists modulate recombinant alpha 6 beta 2 gamma 2 GABAA receptors in transfected human embryonic kidney cells.
Topics: Action Potentials; Azides; Benzodiazepines; Carbolines; Cells, Cultured; Ethanol; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Kidney; Receptors, GABA-A; Recombinant Proteins; Transfection | 1991 |
Stress-protection action of beta-phenyl(GABA): involvement of central and peripheral type benzodiazepine binding sites.
Topics: Animals; Behavior, Animal; Benzodiazepinones; Blood Proteins; Carbolines; Drug Combinations; Female; Flunitrazepam; gamma-Aminobutyric Acid; Male; Premedication; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stress, Physiological; Time Factors | 1990 |
Benzodiazepine agonist and inverse agonist actions on GABAA receptor-operated chloride channels. I. Acute effects of ethanol.
Topics: Animals; Benzodiazepines; Brain; Carbolines; Chloride Channels; Chlorides; Convulsants; Ethanol; Flumazenil; Flunitrazepam; Injections, Intraperitoneal; Male; Membrane Proteins; Mice; Mice, Inbred ICR; Tritium | 1990 |
Benzodiazepine agonist and inverse agonist actions on GABAA receptor-operated chloride channels. II. Chronic effects of ethanol.
Topics: Animals; Azides; Benzodiazepines; Brain; Carbolines; Chloride Channels; Chlorides; Convulsants; Ethanol; Flunitrazepam; GABA Antagonists; Male; Membrane Proteins; Mice; Mice, Inbred ICR; Pyridazines; Receptors, GABA-A; Substance Withdrawal Syndrome; Tritium | 1990 |
Differential benzodiazepine pharmacology of mammalian recombinant GABAA receptors.
Topics: Carbolines; Cells, Cultured; DNA; Flunitrazepam; Humans; Kidney; Membrane Potentials; Receptors, GABA-A; Recombinant Proteins | 1990 |
Anion regulation of agonist and inverse agonist binding to benzodiazepine receptors.
Topics: Animals; Anions; Bromides; Carbolines; Cell Membrane; Cell Membrane Permeability; Cerebral Cortex; Chlorides; Flunitrazepam; Fluorides; gamma-Aminobutyric Acid; Iodides; Ion Channels; Male; Phospholipases A; Phospholipases A2; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stress, Physiological | 1988 |
Chloride channel modulation through the benzodiazepine recognition site.
Topics: Animals; Bicuculline; Carbolines; Cells, Cultured; Chlorides; Convulsants; Flumazenil; Flunitrazepam; Ion Channels; Neurons; Receptors, GABA-A | 1988 |
Ultraviolet irradiation selectively disrupts the gamma-aminobutyric acid/benzodiazepine receptor-linked chloride ionophore.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Chloride Channels; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Proteins; Rats; Rats, Inbred Strains; Receptors, GABA-A; Ultraviolet Rays | 1989 |
Heterogeneity of gamma-aminobutyric acid/benzodiazepine/beta-carboline receptor complex in rat spinal cord.
Topics: Animals; Bicuculline; Binding, Competitive; Carbolines; Cerebellum; Diazepam; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Receptors, GABA-A; Spinal Cord; Synaptic Membranes | 1988 |
Picrate and niflumate block anion modulation of radioligand binding to the gamma-aminobutyric acid/benzodiazepine receptor complex.
Topics: Animals; Anions; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Flunitrazepam; Male; Nicotinic Acids; Niflumic Acid; Picrates; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1988 |
Behavioral differences in an elevated plus-maze: correlation between anxiety and decreased number of GABA and benzodiazepine receptors in mouse cerebral cortex.
Topics: Animals; Anxiety; Brain; Carbolines; Cerebral Cortex; Diazepam; Exploratory Behavior; Flunitrazepam; Male; Mice; Muscimol; Receptors, GABA-A | 1988 |
Benzodiazepine receptors: multiple receptors or multiple conformations?
Topics: Animals; Binding Sites; Brain; Brain Chemistry; Carbolines; Chemical Phenomena; Chemistry; Flunitrazepam; Humans; Kinetics; Models, Chemical; Molecular Conformation; Pyridazines; Radioligand Assay; Rats; Receptors, GABA-A | 1985 |
Benzodiazepine anticonvulsants accelerate and beta-carboline convulsants decelerate the kinetics of [35S]TBPS binding at the chloride ionophore.
Topics: Animals; Anticonvulsants; Benzodiazepines; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Carbolines; Chlorides; Convulsants; Flunitrazepam; In Vitro Techniques; Ionophores; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Membranes | 1985 |
Modulation of gamma-aminobutyric acid-mediated inhibitory synaptic currents in dissociated cortical cell cultures.
Topics: Animals; Bicuculline; Carbolines; Cells, Cultured; Cerebral Cortex; Electric Conductivity; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Membrane Potentials; Neural Inhibition; Rats; Synapses | 1986 |
Specific 3H-DMCM binding to a non-benzodiazepine binding site after silver ion treatment of rat brain membranes.
Topics: Animals; Benzodiazepines; Binding Sites; Binding, Competitive; Brain; Carbolines; Flunitrazepam; In Vitro Techniques; Indoles; Membranes; Midazolam; Nerve Tissue Proteins; Protein Binding; Rats; Receptors, GABA-A; Silver | 1984 |
A study on benzodiazepine receptor binding in audiogenic seizure-susceptible rats.
Topics: Acoustic Stimulation; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Convulsants; Diazepam; Female; Flunitrazepam; In Vitro Techniques; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures | 1984 |
Differential modulation of etazolate or pentobarbital enhanced [3H] muscimol binding by benzodiazepine agonists and inverse agonists.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Binding, Competitive; Carbolines; Cell Membrane; Cerebral Cortex; Convulsants; Etazolate; Flumazenil; Flunitrazepam; Kinetics; Muscimol; Nicotinic Acids; Oxazoles; Pentobarbital; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Barbiturate shift as a tool for determination of efficacy of benzodiazepine-receptor ligands.
Topics: Animals; Benzodiazepines; Brain; Carbolines; Convulsants; Flunitrazepam; In Vitro Techniques; Ionophores; Ligands; Pentobarbital; Rats; Receptors, Cell Surface; Receptors, GABA-A; Sodium Chloride; Synaptic Membranes | 1984 |
Hepatic encephalopathy in rats with thioacetamide-induced acute liver failure is not mediated by endogenous benzodiazepines.
Topics: Animals; Azides; Benzodiazepines; Carbolines; Convulsants; Flunitrazepam; Hepatic Encephalopathy; Liver Failure, Acute; Male; Rats; Rats, Sprague-Dawley; Thioacetamide | 1993 |
Diazepam-insensitive GABAA receptors on postnatal spiral ganglion neurones in culture.
Topics: Animals; Animals, Newborn; Baclofen; Bicuculline; Carbolines; Cells, Cultured; Convulsants; Diazepam; Flunitrazepam; gamma-Aminobutyric Acid; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Spiral Ganglion; Zinc | 1997 |
Modulation of long-term potentiation in CA1 region of mouse hippocampal brain slices by GABAA receptor benzodiazepine site ligands.
Topics: Animals; Carbolines; Convulsants; Dizocilpine Maleate; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Flumazenil; Flunitrazepam; GABA-A Receptor Agonists; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Mice; Quinolones; Receptors, GABA-A | 1997 |
A high-throughput functional assay for characterization of gamma-aminobutyric acid(A) channel modulators using cryopreserved transiently transfected cells.
Topics: Carbolines; Cell Culture Techniques; Cell Line; Cell Membrane; Cryopreservation; Diazepam; DNA; Dose-Response Relationship, Drug; Drug Discovery; Flumazenil; Flunitrazepam; Fluorescent Dyes; Fluorobenzenes; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Membrane Potentials; Receptors, GABA-A; Reproducibility of Results; Spectrometry, Fluorescence; Transfection; Triazoles; Tritium | 2008 |
Rats with different thresholds for DMCM-induced clonic convulsions differ in the sleep-time of diazepam and [(3)H]-Ro 15-4513 binding.
Topics: Animals; Anticonvulsants; Autoradiography; Azides; Benzodiazepines; Carbolines; Convulsants; Diazepam; Differential Threshold; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Flunitrazepam; GABA Modulators; Male; Pentobarbital; Rats; Rats, Wistar; Reaction Time; Seizures; Sleep; Statistics, Nonparametric; Tritium | 2012 |