flunitrazepam has been researched along with methadone in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.11) | 18.7374 |
| 1990's | 4 (22.22) | 18.2507 |
| 2000's | 7 (38.89) | 29.6817 |
| 2010's | 5 (27.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Breimer, DD; de Boer, AG; van Hoogdalem, E | 1 |
| Adir, Y; Bitterman, H; Halpern, P; Nachum, Z | 1 |
| Bosshard, JP; Peters, G; Schwander, D | 1 |
| Camí, J; de Torres, S; Guerra, D; San, L; Solé, A; Ugena, B | 1 |
| Camí, J; Farré, M; Mas, M; Roset, PN; Terán, MT; Torrens, M | 1 |
| Bammer, G; Bell, JR; Masterman, SC; Mattick, RP; Morris, A; Young, MR | 1 |
| Baud, FJ; Borron, SW; Monier, C; Risède, P | 1 |
| Ator, NA; Griffiths, RR; Weerts, EM | 1 |
| Marchi, I; Rudaz, S; Selman, M; Veuthey, JL | 1 |
| Dervaux, A; Kanit, M; Laqueille, X; Launay, C | 1 |
| Castro, AL; Silvestre, A; Tarelho, S; Teixeira, HM | 1 |
| Bogdan, C; Kiss, B; Loghin, F; Pop, A | 1 |
| Daldrup, T; Lerch, O; Temme, O | 1 |
| Jandali, AR; Jung, FJ; Kamphuis, SJM; Sproedt, J | 1 |
4 review(s) available for flunitrazepam and methadone
| Article | Year |
|---|---|
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
Pharmacokinetics of rectal drug administration, Part I. General considerations and clinical applications of centrally acting drugs.
Topics: Administration, Rectal; Antiemetics; Atropine; Carbamazepine; Clonazepam; Delayed-Action Preparations; Diazepam; Flunitrazepam; Humans; Hydromorphone; Intestinal Absorption; Methadone; Methohexital; Midazolam; Morphine; Pharmacokinetics; Phenobarbital; Valproic Acid | 1991 |
[Abuse of alcohol and benzodiazepine during substitution therapy in heroin addicts: a review of the literature].
Topics: Adolescent; Adult; Alcoholism; Benzodiazepines; Buprenorphine; Clonazepam; Clorazepate Dipotassium; Comorbidity; Controlled Clinical Trials as Topic; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Ethanol; Euphoria; Flunitrazepam; Heroin Dependence; Humans; Metabolic Clearance Rate; Methadone; Narcotics; Substance-Related Disorders; Young Adult | 2009 |
[Compartment syndrome of the forearm after intra-arterial self-injection : With a mixture of methadone, flunitrazepam, saliva and water].
Topics: Adult; Compartment Syndromes; Debridement; Drug Users; Fasciotomy; Flunitrazepam; Forearm; Humans; Injections, Intra-Arterial; Male; Methadone; Saliva; Treatment Outcome; Water | 2018 |
2 trial(s) available for flunitrazepam and methadone
| Article | Year |
|---|---|
Abuse liability of flunitrazepam among methadone-maintained patients.
Topics: Adult; Anti-Anxiety Agents; Blood Pressure; Body Temperature; Cross-Over Studies; Double-Blind Method; Electrocardiography; Flunitrazepam; Heart Rate; Humans; Male; Methadone; Narcotics; Opioid-Related Disorders; Psychomotor Performance; Substance-Related Disorders; Surveys and Questionnaires | 1998 |
A pilot study of naltrexone-accelerated detoxification in opioid dependence.
Topics: Adolescent; Adult; Analgesics; Anti-Anxiety Agents; Clonidine; Conscious Sedation; Female; Flunitrazepam; Heroin; Heroin Dependence; Hormones; Humans; Male; Methadone; Middle Aged; Naltrexone; Narcotic Antagonists; Narcotics; Octreotide; Pilot Projects; Substance Withdrawal Syndrome; Time Factors | 1999 |
12 other study(ies) available for flunitrazepam and methadone
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Hyperbaric oxygen therapy for ischaemia of the hand due to intra-arterial injection of methadone and flunitrazepam.
Topics: Adult; Flunitrazepam; Hand; Humans; Hyperbaric Oxygenation; Injections, Intra-Arterial; Ischemia; Male; Methadone; Substance Abuse, Intravenous | 1991 |
[Oral preanesthetic medication in children].
Topics: Administration, Oral; Atropine; Child; Child Behavior; Child, Preschool; Flunitrazepam; Humans; Infant; Methadone; Preanesthetic Medication | 1989 |
Efficacy of clonidine and of methadone in the rapid detoxification of patients dependent on heroin.
Topics: Adolescent; Adult; Analysis of Variance; Anxiety; Blood Pressure; Clonidine; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Female; Flunitrazepam; Heart Rate; Heroin; Humans; Inactivation, Metabolic; Male; Methadone; Substance-Related Disorders | 1985 |
Flunitrazepam variably alters morphine, buprenorphine, and methadone lethality in the rat.
Topics: Animals; Anti-Anxiety Agents; Buprenorphine; Drug Interactions; Flunitrazepam; Injections, Intraperitoneal; Injections, Intravenous; Lethal Dose 50; Male; Methadone; Morphine; Narcotics; Rats; Rats, Sprague-Dawley | 2002 |
Self-injection of flunitrazepam alone and in the context of methadone maintenance in baboons.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Feeding Behavior; Flunitrazepam; GABA Modulators; Injections, Intravenous; Methadone; Opioid-Related Disorders; Papio; Self Administration | 2005 |
Evaluation of the influence of protein precipitation prior to on-line SPE-LC-API/MS procedures using multivariate data analysis.
Topics: Alanine; Blood Proteins; Chemical Precipitation; Cholecalciferol; Chromatography, Liquid; Flunitrazepam; Fluoxetine; Mass Spectrometry; Methadone; Multivariate Analysis; Online Systems; Pyrrolidines; Solid Phase Extraction | 2007 |
Simultaneous analysis of some club drugs in whole blood using solid phase extraction and gas chromatography-mass spectrometry.
Topics: Buprenorphine; Dextropropoxyphene; Flunitrazepam; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Ketamine; Limit of Detection; Methadone; Narcotics; Phencyclidine; Solid Phase Extraction | 2012 |
A rapid UPLC-MS/MS method for simultaneous determination of flunitrazepam, 7-aminoflunitrazepam, methadone and EDDP in human, rat and rabbit plasma.
Topics: Animals; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Female; Flunitrazepam; Humans; Male; Methadone; Pyrrolidines; Rabbits; Rats; Reproducibility of Results; Tandem Mass Spectrometry; Time Factors; Toxicity Tests | 2012 |
Comprehensive automation of the solid phase extraction gas chromatographic mass spectrometric analysis (SPE-GC/MS) of opioids, cocaine, and metabolites from serum and other matrices.
Topics: Acetamides; Analgesics, Opioid; Automation; Cocaine; Codeine; Flunitrazepam; Fluoroacetates; Gas Chromatography-Mass Spectrometry; Humans; Limit of Detection; Methadone; Morphine; Morphine Derivatives; Reproducibility of Results; Robotics; Solid Phase Extraction; Substance Abuse Detection; Trimethylsilyl Compounds | 2014 |