flunitrazepam has been researched along with chlorine in 131 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 58 (44.27) | 18.7374 |
| 1990's | 58 (44.27) | 18.2507 |
| 2000's | 15 (11.45) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Karobath, M; Supavilai, P | 3 |
| Ho, IK; Yu, S | 1 |
| Bowers, BJ; Wehner, JM | 2 |
| Kuriyama, K; Ueha, T | 2 |
| Blakeman, DP; Carter, DB; Hamilton, BJ; Im, HK; Im, WB; Jacobsen, EJ; Petke, JD; Pregenzer, JF | 1 |
| Allan, AM; Baier, LD; Zhang, X | 1 |
| Banerjee, PK; Depaulis, A; Hechler, V; Snead, OC; Vergnes, M | 1 |
| Buck, KJ; Harris, RA; McQuilkin, SJ | 1 |
| Harris, RA; Leidenheimer, NJ | 1 |
| Kellogg, CK; Primus, RJ | 2 |
| Harris, RA; McQuilkin, SJ | 1 |
| Chesley, S; Greenblatt, DJ; Lopez, F; Miller, LG; Schatzki, A; Shader, RI; Thompson, ML | 1 |
| Biggio, G; Concas, A; Foddi, C; Sanna, E; Serra, M | 1 |
| Biggio, G; Concas, A; Sanna, E; Santoro, G; Serra, M | 1 |
| Kuriyama, K; Taguchi, J | 1 |
| Buck, KJ; Harris, RA | 2 |
| Costa, E; Paul, SM; Pritchett, DB; Puia, G; Purdy, RH; Santi, MR; Seeburg, PH; Vicini, S | 1 |
| Barker, JL; Harrison, NL; Majewska, MD; Paul, SM; Schwartz, RD | 1 |
| Costa, E; Mienville, JM; Vicini, S | 2 |
| Havoundjian, H; Skolnick, P; Trullas, R | 1 |
| Barnard, EA; Bilbe, G; Houamed, K; Moss, SJ; Smart, TG; Van Renterghem, C | 1 |
| Cole, RJ; Eldefrawi, AT; Eldefrawi, ME; Gant, DB; Valdes, JJ | 1 |
| David, JA; Pinnock, RD; Sattelle, DB; Wafford, KA | 1 |
| McIntyre, TD; Skolnick, P; Trullas, R | 1 |
| Greenblatt, DJ; Miller, LG; Roy, RB; Shader, RI; Summer, WR | 1 |
| Canonaco, M; McEwen, BS; Pfaff, DW; Schwartz-Giblin, S | 1 |
| Allan, AM; Gallaher, EJ; Gionet, SE; Harris, RA | 1 |
| Mehta, AK; Ticku, MK | 1 |
| Evoniuk, G; Skolnick, P | 1 |
| Allan, AM; Harris, RA | 2 |
| Chiu, TH; Rosenberg, HC; Tietz, EI | 1 |
| Biggio, G; Cau, A; Corda, MG; Laudani, U; Longoni, B; Paci, S; Salvadori, S | 1 |
| Evoniuk, G; Moody, EJ; Skolnick, P | 1 |
| Lehoullier, PF; Ticku, MK | 1 |
| Ebner, J; Ferenci, P; Zimmermann, C | 1 |
| Barnes, EM; Hablitz, JJ; Tehrani, MH | 1 |
| Lopez, F; Miller, LG; Roy, RB; Weill, CL | 1 |
| Ikeda, M; Knapp, RJ; Malatynska, E; Yamamura, HI | 1 |
| Chang, YF; Gao, XM | 1 |
| Bechtel, WD; Ikeda, M; Malatynska, E; Weber, KH; Yamamura, HI | 1 |
| Ticku, MK | 1 |
| Barnett, A; Biggio, G; Corda, MG; Giorgi, O; Longoni, B; Montaldo, S; Ongini, E | 1 |
| Barnes, EM; Tehrani, MH | 1 |
| Gaver, A; Miller, LG; Roy, RB; Weill, CL | 1 |
| Abalis, IM; Eldefrawi, AT; Eldefrawi, ME | 1 |
| Concas, A; Morelli, M; Obata, T; Serra, M; Yamamura, HI | 1 |
| Gallager, DW; Marley, RJ | 1 |
| Kempner, ES; Paul, SM; Schwartz, RD; Skolnick, P; Thomas, JW | 1 |
| Maksay, G; Simonyi, M | 1 |
| Haefely, W; Möhler, H; Richards, JG; Schoch, P | 1 |
| Havoundjian, H; Paul, SM; Skolnick, P | 2 |
| Hammond, JR; Martin, IL | 1 |
| Havoundjian, H; Skolnick, P | 1 |
| Havoundjian, H; Paul, S; Skolnick, P; Trullas, R; Zamir, N | 1 |
| Barker, JL; Harrington, JW; Harrison, NL; Majewska, MD | 1 |
| Olsen, RW; Yang, JS | 1 |
| Drexler, G; Sieghart, W | 1 |
| Braunwalder, A; Cheney, DL; Loo, P; Wood, PL; Yokoyama, N | 1 |
| Dichter, MA; Snodgrass, SR; White, WF | 1 |
| Dehaven, R; Pong, SS; Wang, CC | 1 |
| Squires, RF | 1 |
| Asano, T; Ogasawara, N | 1 |
| Gee, KW; Yamamura, HI | 1 |
| Horton, RW; Prestwich, SA; Stapleton, SR | 1 |
| Braestrup, C; Hetmar, O; Nielsen, M | 1 |
| Lo, MM; Snyder, SH | 1 |
| Olsen, RW; Stephenson, FA | 1 |
| Braestrup, C; Honoré, T; Jensen, LH; Nielsen, M; Petersen, EN | 1 |
| Kato, R; Muraki, T; Yamazoe, Y | 1 |
| Grayson, DR; Harris, BT; Vicini, S; Zhu, WJ | 1 |
| Burnham, WM; Lôscher, W; Nobrega, JN; Richter, A | 1 |
| Abeliovich, A; Harris, RA; McQuilkin, SJ; Paylor, R; Tonegawa, S; Wehner, JM | 1 |
| Dunwiddie, TV; Harris, RA; Klein, RL; Mascia, MP; McQuilkin, SJ; Proctor, WR; Whatley, V; Whiting, PJ | 1 |
| Hirouchi, M; Ichida, T; Kuriyama, K; Narihara, R; Roberts, E | 1 |
| Inglefield, JR; Kellogg, CK; Sieghart, W | 1 |
| Inglefield, JR; Kellogg, CK | 1 |
| Allan, AM; Harris, RA; McQuilkin, SJ; Mihic, SJ; Whatley, VJ | 1 |
| Blandl, T; Kardos, J | 1 |
| Hu, XJ; Ticku, MK | 1 |
| Harris, RA; Klein, RL; McQuilkin, SJ; Sanna, E; Whiting, PJ | 1 |
| Moore, FL; Murray, TF; Orchinik, M | 1 |
| Ho, IK; Kimura, T; Miyaoka, T; Saunders, PA; Tseng, YT | 1 |
| Harris, RA; McQuilkin, SJ; Mihic, SJ; Whatley, VJ | 1 |
| Corda, MG; Driscoll, P; Escorihuela, RM; Giorgi, O; Lecca, D; Orlandi, M | 1 |
| Davies, MF; Loew, GH; Maguire, PA | 1 |
| Biggio, G; Concas, A; Dazzi, L; Maciocco, E; Mascia, MP; Ongini, E; Santoro, G | 1 |
| Dunn, SM; Thuynsma, RP | 1 |
| Liu, CC; Snead, OC | 1 |
| Harris, B; Skolnick, P; Wong, G | 1 |
| Harris, BD; Moody, EJ; Skolnick, P | 1 |
| Belonga, KL; Carter, DB; Im, HK; Im, WB; Jacobsen, EJ; Petke, JD; Sethy, VH; Stelzer, LS; Tang, AH; TenBrink, RE; VonVoigtlander, PF | 1 |
| Brozowski, SJ; Hadingham, KL; Harris, RA; Whatley, VJ; Whiting, PJ | 1 |
| Mehta, AK; Shank, RP | 1 |
| Allan, AM; Engel, SR; Gandet, EA; Jackson, KA | 1 |
| Hatta, S; Saito, T; Takahata, N; Toki, S | 1 |
| Kivastik, T; Liljequist, S; Pokk, P; Sobol, D; Zharkovsky, A | 1 |
| Andersson, G; Enerbäck, C; Engel, JA; Söderpalm, B | 1 |
| Deitrich, RA; Liu, Y | 1 |
| Acquas, C; Biggio, G; Floris, C; Fontana, SN; Maciocco, E; Maira, G; Massa, F; Pau, D; Sanna, E; Tuveri, F | 1 |
| Chistina Grobin, A; Devaud, LL; Inglefield, JR; Morrow, AL; Schwartz-Bloom, RD | 1 |
| Crites, GJ; Goldenberg, R; Malatynska, E; Schindler, NL; Tunnicliff, G; Yochum, A | 1 |
| Crites, GJ; Goldenberg, R; Harrawood, D; Malatynska, E; Matheson, GK; Schindler, NL; Tunnicliff, G; Weinzapfel, D; Yochum, A | 1 |
| Fiacco, TT; Galler, JR; Rosene, DL; Shultz, PL; Shumsky, JS; Tonkiss, J; Vincitore, M | 1 |
| Betti, L; Bistocchi, M; Giannaccini, G; Gori, M; Lucacchini, A | 1 |
| Fiszer de Plazas, S; Pignataro, L | 1 |
| Baufreton, J; Bioulac, B; Dovero, S; Dufy, B; Garret, M; Taupignon, A | 1 |
| Alkana, RL; Bolger, MB; Davies, DL; McCauley, LD | 1 |
| Hodge, CW; Homanics, GE; Khisti, RT; Kralic, JE; Morrow, AL; O'Buckley, TK | 1 |
| Akesson, P; Engel, JA; Söderpalm, B; Svensson, AI | 1 |
| Bäckström, T; Lundgren, P; Strömberg, J; Wang, M | 1 |
| Chadda, R; Devaud, LL | 1 |
| Ducroc, R; Lacapere, JJ; Ostuni, MA; Papadopoulos, V; Péranzi, G; Tonon, MC | 1 |
| Hong, JT; Hwang, BY; Kwon, BM; Lee, SH; Lee, YS; Ma, Y; Oh, KW; Seo, JJ | 1 |
| Furtmueller, B; Furtmueller, R; Huck, S; Marder, M; Paladini, AC; Ramerstorfer, J; Sieghart, W; Wasowski, C | 1 |
| Frandsen, A; Pomés, A; Rodríguez-Farré, E; Sanfeliu, C; Schousboe, A; Suñol, C | 1 |
| Nabeshima, A; Saito, T; Takahata, N; Toki, S | 1 |
| Li, TK; Lumeng, L; McBride, WJ; Thielen, RJ | 1 |
| File, SE; Hogg, S; Mills, AD | 1 |
| Braun, D; Chmielewski, PA; Kane, JM; Miller, JA | 1 |
| Rodríguez-Farré, E; Suñol, C; Vale, C; Vilaró, MT | 1 |
| Cleton, A; Danhof, M; Ghijsen, W; Odman, J; Van der Graaf, PH; Voskuyl, R | 1 |
| Grobin, AC; Morrow, AL | 1 |
4 review(s) available for flunitrazepam and chlorine
| Article | Year |
|---|---|
Benzodiazepine receptors resolved.
Topics: Animals; Antibodies, Monoclonal; Autoradiography; Benzodiazepines; Benzodiazepinones; Bicuculline; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Chlorides; Clonazepam; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Histocytochemistry; Humans; Immunologic Techniques; Ionophores; Muscimol; Neurons; Radioisotopes; Radioligand Assay; Receptors, GABA-A; Spinal Cord; Synapses; Tissue Distribution | 1986 |
GABA receptors regulate the affinities of anions required for brain specific benzodiazepine binding.
Topics: Animals; Anions; Brain; Chlorides; Flunitrazepam; Organ Specificity; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A | 1981 |
Biochemical pharmacology of the GABA receptor-ionophore protein complex.
Topics: Animals; Brain; Chlorides; Flunitrazepam; Humans; Ion Channels; Ionophores; Kinetics; Muscimol; Nerve Tissue Proteins; Picrotoxin; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter; Sesterterpenes | 1983 |
Benzodiazepine receptor ligands with negative efficacy: chloride channel coupling.
Topics: Animals; Barbiturates; Brain; Carbolines; Chlorides; Flunitrazepam; Humans; Ion Channels; Ligands; Membranes; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
127 other study(ies) available for flunitrazepam and chlorine
| Article | Year |
|---|---|
Stimulation of benzodiazepine receptor binding by SQ 20009 is chloride-dependent and picrotoxin-sensitive.
Topics: Animals; Benzodiazepines; Brain; Chlorides; Etazolate; Flunitrazepam; In Vitro Techniques; Membranes; Nicotinic Acids; Picrotoxin; Rats; Receptors, Drug; Sodium Chloride; Stimulation, Chemical | 1979 |
Effects of acute pentobarbital administration on GABAA receptor-regulated chloride uptake in rat brain synaptoneurosomes.
Topics: Animals; Brain; Cerebellum; Cerebral Cortex; Chlorides; Flunitrazepam; Male; Muscimol; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes | 1992 |
Biochemical and behavioral effects of steroids on GABAA receptor function in long- and short-sleep mice.
Topics: Anesthetics; Animals; Behavior, Animal; Brain Chemistry; Chlorides; Desoxycorticosterone; Ethanol; Flunitrazepam; Male; Mice; Mice, Inbred Strains; Pentobarbital; Pregnanediones; Pregnenolone; Receptors, GABA-A; Sleep; Species Specificity; Steroids | 1992 |
Adrenalectomy and stress modulate GABAA receptor function in LS and SS mice.
Topics: Adrenalectomy; Animals; Brain; Cerebellum; Cerebral Cortex; Chlorides; Corticosterone; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Learning; Male; Mice; Mice, Inbred Strains; Receptors, GABA-A; Reference Values; Sleep; Stress, Psychological | 1992 |
Functional alterations in cerebral GABAA receptor complex associated with formation of alcohol dependence: analysis using GABA-dependent 36Cl- influx into neuronal membrane vesicles.
Topics: Administration, Inhalation; Alcohol Withdrawal Delirium; Alcoholism; Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; Muscimol; Neurons; Radioligand Assay; Receptors, GABA-A; Synaptic Membranes; Synaptic Vesicles | 1992 |
Characterization of functional interactions of imidazoquinoxaline derivatives with benzodiazepine-gamma-aminobutyric acidA receptors.
Topics: Animals; Anti-Anxiety Agents; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chloride Channels; Chlorides; Chlorine; Cloning, Molecular; Drug Interactions; Electrophysiology; Flunitrazepam; GABA-A Receptor Antagonists; Kinetics; Male; Membrane Proteins; Models, Chemical; Molecular Conformation; Oxadiazoles; Quinoxalines; Radioisotopes; Rats; Rats, Inbred Strains; Receptors, GABA-A; Structure-Activity Relationship; Synaptosomes; Tritium | 1992 |
Effects of lorazepam tolerance and withdrawal on GABAA receptor-operated chloride channels.
Topics: Animals; Appetite Depressants; Binding Sites; Brain; Carbolines; Chloride Channels; Chlorides; Diazepam; Drug Interactions; Ethanol; Flunitrazepam; Ion Channels; Lorazepam; Male; Membrane Proteins; Mice; Mice, Inbred ICR; Phenobarbital; Receptors, GABA-A | 1992 |
The GABAA receptor complex in experimental absence seizures in rat: an autoradiographic study.
Topics: Animals; Autoradiography; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Chlorides; Convulsants; Epilepsy, Absence; Flunitrazepam; GABA-A Receptor Antagonists; Ion Channels; Ionophores; Male; Membrane Proteins; Muscimol; Organ Specificity; Pyramidal Tracts; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A; Sulfur Radioisotopes; Tritium | 1992 |
Ethanol-induced alterations in the function of cerebral GABAA receptor complex: effect on GABA-dependent 36Cl- influx into cerebral membrane vesicles.
Topics: Animals; Brain; Chloride Channels; Chlorides; Culture Techniques; Dose-Response Relationship, Drug; Ethanol; Flunitrazepam; Isoquinolines; Membrane Proteins; Mice; Muscimol; Radioligand Assay; Receptors, GABA-A; Synaptic Membranes; Synaptic Vesicles | 1991 |
Modulation of gamma-aminobutyric acidA receptor-operated chloride channels by benzodiazepine inverse agonists is related to genetic differences in ethanol withdrawal seizure severity.
Topics: Animals; Benzodiazepines; Carbolines; Chloride Channels; Chlorides; Convulsants; Ethanol; Flunitrazepam; Genetic Predisposition to Disease; Male; Membrane Proteins; Mice; Mice, Inbred Strains; Muscimol; Receptors, GABA-A; Seizures; Substance Withdrawal Syndrome | 1991 |
A transient osmotic permeabilization method for the introduction of impermeant molecules into functional brain membrane vesicles.
Topics: Alkaline Phosphatase; Animals; Capsules; Carbon Radioisotopes; Cell Membrane; Cell Membrane Permeability; Chloride Channels; Chlorides; Chlorine; Concanavalin A; Flunitrazepam; Hypotonic Solutions; Membrane Proteins; Mice; Mice, Inbred ICR; Muscimol; Pyridazines; Radioisotope Dilution Technique; Radioisotopes; Receptors, Concanavalin A; Receptors, GABA-A; Sucrose; Tritium | 1991 |
Gonadal status and pubertal age influence the responsiveness of the benzodiazepine/GABA receptor complex to environmental challenge in male rats.
Topics: Aging; Animals; Cerebral Cortex; Chlorides; Flunitrazepam; Handling, Psychological; Male; Orchiectomy; Rats; Receptors, GABA-A; Reference Values; Sexual Maturation; Stress, Psychological; Tritium | 1991 |
Factors affecting actions of ethanol on GABA-activated chloride channels.
Topics: Animals; Chlorides; Cold Temperature; Ethanol; Female; Flunitrazepam; gamma-Aminobutyric Acid; Ion Channels; Mice; Pentobarbital; Time Factors | 1990 |
Chronic morphine administration augments benzodiazepine binding and GABAA receptor function.
Topics: Animals; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Chlorine; Flunitrazepam; In Vitro Techniques; Ion Channels; Male; Mice; Morphine; Muscimol; Naltrexone; Radioisotopes; Receptors, GABA-A; Sulfur Radioisotopes | 1990 |
Experience influences environmental modulation of function at the benzodiazepine (BZD)/GABA receptor chloride channel complex.
Topics: Animals; Anxiety; Cell Membrane; Cerebral Cortex; Chloride Channels; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; Ion Channels; Male; Membrane Proteins; Rats; Rats, Inbred Strains; Receptors, GABA-A; Social Environment | 1991 |
Failure of gamma-hydroxybutyrate to alter the function of the GABAA receptor complex in the rat cerebral cortex.
Topics: Animals; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorides; Diazepam; Flunitrazepam; In Vitro Techniques; Ion Channels; Isoniazid; Male; Nerve Tissue Proteins; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sodium Oxybate; Synaptic Transmission | 1991 |
Neurochemical action of the general anaesthetic propofol on the chloride ion channel coupled with GABAA receptors.
Topics: Anesthetics; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Chlorides; Flunitrazepam; Male; Membrane Proteins; Muscimol; Propofol; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1991 |
Functional modulation of cerebral gamma-aminobutyric acidA receptor/benzodiazepine receptor/chloride ion channel complex with ethyl beta-carboline-3-carboxylate: presence of independent binding site for ethyl beta-carboline-3-carboxylate.
Topics: Animals; Baclofen; Binding Sites; Brain; Carbolines; Cells, Cultured; Chloride Channels; Chlorides; Drug Interactions; Flunitrazepam; Male; Membrane Proteins; Mice; Muscimol; Receptors, GABA-A; Tritium | 1990 |
Benzodiazepine agonist and inverse agonist actions on GABAA receptor-operated chloride channels. I. Acute effects of ethanol.
Topics: Animals; Benzodiazepines; Brain; Carbolines; Chloride Channels; Chlorides; Convulsants; Ethanol; Flumazenil; Flunitrazepam; Injections, Intraperitoneal; Male; Membrane Proteins; Mice; Mice, Inbred ICR; Tritium | 1990 |
Benzodiazepine agonist and inverse agonist actions on GABAA receptor-operated chloride channels. II. Chronic effects of ethanol.
Topics: Animals; Azides; Benzodiazepines; Brain; Carbolines; Chloride Channels; Chlorides; Convulsants; Ethanol; Flunitrazepam; GABA Antagonists; Male; Membrane Proteins; Mice; Mice, Inbred ICR; Pyridazines; Receptors, GABA-A; Substance Withdrawal Syndrome; Tritium | 1990 |
Neurosteroids act on recombinant human GABAA receptors.
Topics: Benzodiazepines; Cell Line, Transformed; Cell Membrane Permeability; Chlorides; Desoxycorticosterone; Electric Conductivity; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Kidney; Membrane Potentials; Pentobarbital; Pregnanolone; Receptors, GABA-A; Recombinant Proteins; Transfection | 1990 |
Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor.
Topics: 20-alpha-Dihydroprogesterone; Animals; Binding, Competitive; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Chlorides; Desoxycorticosterone; Drug Synergism; Flunitrazepam; Hippocampus; In Vitro Techniques; Ion Channels; Progesterone; Rats; Receptors, GABA-A; Spinal Cord | 1986 |
Flunitrazepam action on the GABA-Cl ionophore complex in rat cortical neurons in culture: a patch-clamp study.
Topics: Animals; Bicuculline; Cerebral Cortex; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; Ion Channels; Neurons; Osmolar Concentration; Rats | 1986 |
Stress-induced changes in t-[35S]butylbicyclophosphorothionate binding to gamma-aminobutyric acid-gated chloride channels are mimicked by in vitro occupation of benzodiazepine receptors.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cerebral Cortex; Chlorides; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Ion Channels; Kinetics; Male; Membranes; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stress, Physiological; Swimming | 1987 |
Functional expression in the Xenopus oocyte of messenger ribonucleic acids encoding brain neurotransmitter receptors: further characterisation of the implanted GABA receptor.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chick Embryo; Chlorides; Cloning, Molecular; DNA; Dose-Response Relationship, Drug; Flunitrazepam; gamma-Aminobutyric Acid; Gene Expression Regulation; Glycosylation; Ion Channels; Oocytes; Poly A; Receptors, GABA-A; RNA; RNA, Messenger; Xenopus | 1987 |
Action of tremorgenic mycotoxins on GABAA receptor.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Electric Organ; Flunitrazepam; In Vitro Techniques; Ion Channels; Male; Muscimol; Mycotoxins; Rats; Rats, Inbred Strains; Receptors, GABA-A; Torpedo; Tremor | 1987 |
GABA receptors on the cell-body membrane of an identified insect motor neuron.
Topics: Androstanes; Animals; Azasteroids; Bicuculline; Chlorides; Cockroaches; Dibenzazepines; Dose-Response Relationship, Drug; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Ion Channels; Male; Membrane Potentials; Microelectrodes; Motor Neurons; Nipecotic Acids; Periplaneta; Picrotoxin; Receptors, GABA-A | 1988 |
Differences in the biophysical properties of the benzodiazepine/gamma-aminobutyric acid receptor chloride channel complex in the long-sleep and short-sleep mouse lines.
Topics: Animals; Azides; Benzodiazepines; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; Heart; Ion Channels; Male; Mice; Mice, Mutant Strains; Receptors, GABA-A; Sleep | 1988 |
Chronic benzodiazepine administration. II. Discontinuation syndrome is associated with upregulation of gamma-aminobutyric acidA receptor complex binding and function.
Topics: Animals; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorides; Drug Tolerance; Flumazenil; Flunitrazepam; Ion Channels; Lorazepam; Male; Mice; Motor Activity; Muscimol; Receptors, GABA-A; Time Factors | 1988 |
Effects of in vivo estradiol and progesterone on tritiated flunitrazepam binding in rat spinal cord.
Topics: Animals; Autoradiography; Chlorides; Estradiol; Estrus; Female; Flunitrazepam; Ion Channels; Ovariectomy; Progesterone; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord | 1988 |
Genetic selection for benzodiazepine ataxia produces functional changes in the gamma-aminobutyric acid receptor chloride channel complex.
Topics: Animals; Ataxia; Chlorides; Diazepam; Ethanol; Flunitrazepam; Ion Channels; Isoxazoles; Mice; Muscimol; Phenobarbital; Receptors, GABA-A; Time Factors | 1988 |
Developmental aspects of benzodiazepine receptors and GABA-gated chloride channels in primary cultures of spinal cord neurons.
Topics: Animals; Cells, Cultured; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; Ion Channels; Kinetics; Mice; Mice, Inbred C57BL; Receptors, GABA-A; Spinal Cord; Time Factors | 1988 |
Anion regulation of agonist and inverse agonist binding to benzodiazepine receptors.
Topics: Animals; Anions; Bromides; Carbolines; Cell Membrane; Cell Membrane Permeability; Cerebral Cortex; Chlorides; Flunitrazepam; Fluorides; gamma-Aminobutyric Acid; Iodides; Ion Channels; Male; Phospholipases A; Phospholipases A2; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stress, Physiological | 1988 |
Chloride channel modulation through the benzodiazepine recognition site.
Topics: Animals; Bicuculline; Carbolines; Cells, Cultured; Chlorides; Convulsants; Flumazenil; Flunitrazepam; Ion Channels; Neurons; Receptors, GABA-A | 1988 |
Sensitivity to ethanol hypnosis and modulation of chloride channels does not cosegregate with pentobarbital sensitivity in HS mice.
Topics: Animals; Arousal; Brain; Chloride Channels; Chlorides; Dose-Response Relationship, Drug; Drug Tolerance; Ethanol; Flunitrazepam; Ion Channels; Male; Membrane Proteins; Mice; Muscimol; Pentobarbital; Receptors, GABA-A; Sleep Stages | 1989 |
Genetic differences in coupling of benzodiazepine receptors to chloride channels.
Topics: Animals; Cerebral Cortex; Chloride Channels; Chlorides; Ethanol; Flunitrazepam; Ion Channels; Male; Membrane Proteins; Mice; Muscimol; Receptors, GABA-A; Sleep | 1989 |
Regional GABA/benzodiazepine receptor/chloride channel coupling after acute and chronic benzodiazepine treatment.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Bicuculline; Brain; Chlorides; Diazepam; Flunitrazepam; Flurazepam; gamma-Aminobutyric Acid; Ion Channels; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stimulation, Chemical | 1989 |
Distribution and pharmacological properties of the GABAA/benzodiazepine/chloride ionophore receptor complex in the brain of the fish Anguilla anguilla.
Topics: Anguilla; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Convulsants; Flunitrazepam; gamma-Aminobutyric Acid; Ionophores; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, GABA-A; Tissue Distribution | 1989 |
Ultraviolet irradiation selectively disrupts the gamma-aminobutyric acid/benzodiazepine receptor-linked chloride ionophore.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Chloride Channels; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Proteins; Rats; Rats, Inbred Strains; Receptors, GABA-A; Ultraviolet Rays | 1989 |
The pharmacological properties of GABA receptor-coupled chloride channels using 36Cl-influx in cultured spinal cord neurons.
Topics: Animals; Cells, Cultured; Chloride Channels; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; Membrane Proteins; Mice; Mice, Inbred C57BL; Receptors, GABA-A; Spinal Cord | 1989 |
Cerebral glutamine metabolism: study of modulatory effects of glutamine on gamma-aminobutyric acid-ergic neurotransmission.
Topics: Animals; Biological Transport; Brain; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; Glutamine; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes | 1989 |
Chronic exposure of developing cortical neurons to GABA down-regulates GABA/benzodiazepine receptors and GABA-gated chloride currents.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Chick Embryo; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; Membrane Potentials; Neural Inhibition; Receptors, GABA-A | 1989 |
Persistent alterations in GABAA receptor binding and function after prenatal lorazepam administration in the chick.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chick Embryo; Chickens; Chlorides; Female; Flunitrazepam; Lorazepam; Muscimol; Pregnancy; Prenatal Exposure Delayed Effects; Radioligand Assay; Receptors, GABA-A | 1989 |
Amoxapine inhibition of GABA-stimulated chloride conductance: investigations of potential sites of activity.
Topics: Amoxapine; Animals; Cerebral Cortex; Chlorides; Dibenzoxazepines; Dose-Response Relationship, Drug; Flumazenil; Flunitrazepam; GABA Antagonists; Ligands; Male; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1989 |
Enhancement of benzodiazepine receptor binding by L-lysine is chloride-dependent and due to increase in binding affinity.
Topics: Animals; Cattle; Chlorides; Flunitrazepam; In Vitro Techniques; Kinetics; Lysine; Pentylenetetrazole; Picrotoxin; Receptors, GABA-A; Sesterterpenes; Synaptic Membranes | 1989 |
Relative efficacies of 1,4-diazepines on GABA-stimulated chloride influx in rat brain vesicles.
Topics: Animals; Anti-Anxiety Agents; Azepines; Cell Membrane; Cerebral Cortex; Chlorides; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1989 |
Behavioral and functional studies indicate a role for GABAAergic transmission in the actions of ethanol.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Chlorides; Ethanol; Flunitrazepam; Male; Mice; Mice, Inbred C57BL; Picrotoxin; Rats; Receptors, GABA-A; Seizures; Spinal Cord | 1987 |
gamma-Aminobutyric acid and pentobarbital enhance 2-[3H]oxoquazepam binding to type I benzodiazepine recognition sites in rat and human brain.
Topics: Adult; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Brain; Chlorides; Drug Synergism; Female; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tritium | 1988 |
GABA down-regulates the GABA/benzodiazepine receptor complex in developing cerebral neurons.
Topics: Animals; Brain; Cells, Cultured; Chick Embryo; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Receptors, GABA-A | 1988 |
Lorazepam administration during embryonic development alters GABAA receptor binding and function.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chick Embryo; Chlorides; Embryonic and Fetal Development; Flunitrazepam; Lorazepam; Receptors, GABA-A; Subcellular Fractions | 1988 |
Actions of avermectin B1a on the gamma-aminobutyric acidA receptor and chloride channels in rat brain.
Topics: Animals; Bicuculline; Binding, Competitive; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Chlorides; Dose-Response Relationship, Drug; Flunitrazepam; Ivermectin; Kinetics; Male; Membrane Proteins; Muscimol; Rats; Receptors, GABA-A | 1986 |
Modulation of GABA-stimulated chloride influx into membrane vesicles from rat cerebral cortex by benzodiazepines and nonbenzodiazepines.
Topics: Animals; Anti-Anxiety Agents; Cell Membrane; Cerebral Cortex; Chlorides; Clonazepam; Diazepam; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Rats; Rats, Inbred Strains | 1988 |
Chronic diazepam treatment produces regionally specific changes in GABA-stimulated chloride influx.
Topics: Animals; Cerebellum; Cerebral Cortex; Chlorides; Diazepam; Flunitrazepam; gamma-Aminobutyric Acid; Male; Membranes; Rats; Rats, Inbred Strains | 1989 |
Radiation inactivation studies of the benzodiazepine/gamma-aminobutyric acid/chloride ionophore receptor complex.
Topics: Animals; Barbiturates; Benzodiazepines; Benzodiazepinones; Binding Sites; Brain; Carbolines; Cell Membrane; Chlorides; Diazepam; Flumazenil; Flunitrazepam; Ionophores; Male; Molecular Weight; Muscimol; Picrotoxin; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
Benzodiazepine anticonvulsants accelerate and beta-carboline convulsants decelerate the kinetics of [35S]TBPS binding at the chloride ionophore.
Topics: Animals; Anticonvulsants; Benzodiazepines; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Carbolines; Chlorides; Convulsants; Flunitrazepam; In Vitro Techniques; Ionophores; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Membranes | 1985 |
Acute, stress-induced changes in the benzodiazepine/gamma-aminobutyric acid receptor complex are confined to the chloride ionophore.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bromides; Cerebral Cortex; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Iodides; Ionophores; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stress, Physiological; Sulfur Radioisotopes; Swimming; Tritium | 1986 |
Rapid, stress-induced modification of the benzodiazepine receptor-coupled chloride ionophore.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorides; Flunitrazepam; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stimulation, Chemical; Stress, Physiological; Swimming; Temperature | 1986 |
Solubilization of the benzodiazepine/gamma-aminobutyric acid receptor complex: comparison of the detergents octylglucopyranoside and 3-[(3-cholamidopropyl)-dimethylammonio]1-propanesulfonate (CHAPS).
Topics: Animals; Carbolines; Cerebellum; Chlorides; Cholic Acids; Drug Stability; Flunitrazepam; gamma-Aminobutyric Acid; Glucosides; Glycosides; Male; Phospholipids; Pyrazoles; Rats; Receptors, GABA-A; Solubility; Synaptic Membranes | 1986 |
A quantitative relationship between Cl- enhanced [3H]flunitrazepam and [35S]t-butylbicyclophosphorothionate binding to the benzodiazepine/GABA receptor chloride ionophore complex.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cerebral Cortex; Chlorides; Flunitrazepam; In Vitro Techniques; Male; Phospholipases A; Phospholipases A2; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stimulation, Chemical | 1986 |
Environmentally-induced modification of the benzodiazepine/GABA receptor coupled chloride ionophore.
Topics: Animals; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Convulsants; Environment; Flunitrazepam; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stress, Physiological; Swimming | 1987 |
Structure-activity relationships for steroid interaction with the gamma-aminobutyric acidA receptor complex.
Topics: Animals; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Desoxycorticosterone; Electric Conductivity; Ethanol; Evoked Potentials; Flunitrazepam; Muscimol; Pregnanes; Progesterone; Rats; Rats, Inbred Strains; Receptors, GABA-A; Steroids; Structure-Activity Relationship | 1987 |
gamma-Aminobutyric acid receptor-regulated 36Cl- flux in mouse cortical slices.
Topics: Androstanes; Animals; Azasteroids; Barbiturates; Cerebral Cortex; Chlorides; Dose-Response Relationship, Drug; Electrophysiology; Flunitrazepam; Male; Mathematics; Mice; Muscimol; Receptors, GABA-A | 1987 |
Evidence for association of a high affinity avermectin binding site with the benzodiazepine receptor.
Topics: Animals; Binding Sites; Binding, Competitive; Cell Membrane; Cerebellar Cortex; Chlorides; Flunitrazepam; In Vitro Techniques; Ivermectin; Lactones; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Sesterterpenes; Temperature | 1984 |
In vitro characterization of benzodiazepine receptor agonists, antagonists, inverse agonists and agonist/antagonists.
Topics: Animals; Brain; Chlorides; Etazolate; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Muscimol; Rats; Receptors, GABA-A | 1984 |
Benzodiazepine binding and interactions with the GABA receptor complex in living cultures of rat cerebral cortex.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Binding, Competitive; Cells, Cultured; Cerebral Cortex; Chlorides; Diazepam; Fetus; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Membrane Potentials; Neurons; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1981 |
Action of pyrazolopyridines as modulators of [3H]flunitrazepam binding to the gaba/benzodiazepine receptor complex of the cerebellum.
Topics: Animals; Anti-Anxiety Agents; Bicuculline; Binding Sites; Cerebellum; Chlorides; Etazolate; Flunitrazepam; Isoxazoles; Male; Muscimol; Nicotinic Acids; Pyrazoles; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Tritium | 1981 |
Stimulation of benzodiazepine binding to rat brain membranes and solubilized receptor complex by avermectin B1a and gamma-aminobutyric acid.
Topics: Animals; Anthelmintics; Anti-Anxiety Agents; Bicuculline; Brain; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; Ion Channels; Ivermectin; Lactones; Male; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Synaptic Membranes | 1981 |
The effect of temperature and chloride ions on the stimulation of [3H]flunitrazepam binding by the muscimol analogues THIP and piperidine-4-sulfonic acid.
Topics: Animals; Anti-Anxiety Agents; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Oxazoles; Piperidines; Rats; Stimulation, Chemical; Temperature; Tritium | 1980 |
Chloride-dependent stimulation of GABA and benzodiazepine receptor binding by pentobarbital.
Topics: Animals; Brain; Cattle; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Pentobarbital; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A | 1981 |
A novel pyrazoloquinoline that interacts with brain benzodiazepine receptors: characterization of some in vitro and in vivo properties of CGS 9896.
Topics: Animals; Anticonvulsants; Brain; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, GABA-A | 1982 |
Regional heterogeneity of benzodiazepine binding sites in rat brain.
Topics: Animals; Binding, Competitive; Brain; Carbolines; Cerebellum; Chlorides; Diazepam; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Kinetics; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1982 |
Decreased number of benzodiazepine receptors in frontal cortex of rat brain following long-term lithium treatment.
Topics: Animals; Benzodiazepines; Brain; Cerebral Cortex; Chlorides; Flunitrazepam; Kinetics; Lithium; Lithium Chloride; Lysergic Acid Diethylamide; Male; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Tissue Distribution | 1983 |
Two distinct solubilized benzodiazepine receptors: differential modulation by ions.
Topics: Animals; Anions; Brain; Cations, Divalent; Cattle; Chlorides; Female; Flunitrazepam; gamma-Aminobutyric Acid; Hot Temperature; Oxidation-Reduction; Receptors, Cell Surface; Receptors, GABA-A; Solubility | 1983 |
Inhibition of benzodiazepine and GABA receptor binding by amino-gamma-carbolines and other amino acid pyrolysate mutagens.
Topics: Animals; Binding, Competitive; Carbolines; Chlorides; Diazepam; Flunitrazepam; Harmine; Indoles; Ion Channels; Kinetics; Male; Mice; Mice, Inbred Strains; Muscimol; Mutagens; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Seizures | 1984 |
NMDA-mediated modulation of gamma-aminobutyric acid type A receptor function in cerebellar granule neurons.
Topics: Animals; Cells, Cultured; Cerebellum; Chlorides; Flunitrazepam; Furosemide; gamma-Aminobutyric Acid; Ion Channel Gating; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Potassium; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Zinc | 1995 |
Alterations in the brain GABAA/benzodiazepine receptor-chloride ionophore complex in a genetic model of paroxysmal dystonia: a quantitative autoradiographic analysis.
Topics: Animals; Autoradiography; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Cricetinae; Dystonia; Flunitrazepam; Ionophores; Male; Models, Genetic; Muscimol; Radiography; Receptors, GABA-A | 1995 |
Mutant mice lacking the gamma isoform of protein kinase C show decreased behavioral actions of ethanol and altered function of gamma-aminobutyrate type A receptors.
Topics: Animals; Base Sequence; Body Temperature; Cerebellum; Cerebral Cortex; Chlorides; DNA Primers; Ethanol; Female; Flunitrazepam; Isoenzymes; Male; Mice; Mice, Mutant Strains; Molecular Sequence Data; Pentobarbital; Polymerase Chain Reaction; Posture; Protein Kinase C; Receptors, GABA-A; Reflex | 1995 |
Ethanol increases GABAA responses in cells stably transfected with receptor subunits.
Topics: Animals; Cattle; Cells, Cultured; Chloride Channels; Chlorides; Dose-Response Relationship, Drug; Ethanol; Flunitrazepam; Mice; Pentobarbital; Receptors, GABA-A; Transfection | 1995 |
Effects of thyroxine and its related compounds on cerebral GABA receptors: inhibitory action on benzodiazepine recognition site in GABAA receptor complex.
Topics: Animals; Benzodiazepines; Binding Sites; Brain; Chlorides; Dextrothyroxine; Dose-Response Relationship, Drug; Fenclonine; Flunitrazepam; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; In Vitro Techniques; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Synaptic Membranes; Thyroxine; Triiodothyronine | 1994 |
Immunohistochemical and neurochemical evidence for GABAA receptor heterogeneity between the hypothalamus and cortex.
Topics: Animals; Cerebral Cortex; Chlorides; Diazepam; Flunitrazepam; gamma-Aminobutyric Acid; Hypothalamus; Male; Rats; Receptors, GABA-A | 1994 |
Hypothalamic GABAA receptor blockade modulates cerebral cortical systems sensitive to acute stressors.
Topics: Animals; Behavior, Animal; Bicuculline; Brain Chemistry; Cerebral Cortex; Chlorides; Dopamine; Flunitrazepam; Frontal Lobe; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Male; Rats; Stress, Psychological | 1994 |
Gamma-aminobutyric acidA receptor function is inhibited by microtubule depolymerization.
Topics: Animals; Biological Transport; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Chlorides; Colchicine; Convulsants; Dose-Response Relationship, Drug; Flunitrazepam; Histones; Humans; Lumicolchicines; Membranes; Mice; Microtubules; Muscimol; Nocodazole; Paclitaxel; Phosphorylation; Receptors, GABA-A; Vinblastine; Xenopus | 1994 |
Inhibition of a gamma aminobutyric acid A receptor by caffeine.
Topics: Animals; Caffeine; Cerebral Cortex; Chlorides; Chlorine; Dantrolene; Flunitrazepam; GABA-A Receptor Antagonists; In Vitro Techniques; Kinetics; Male; Membranes; Radioisotopes; Rats; Rats, Wistar | 1994 |
Development pattern of the GABAA-benzodiazepine receptor ionophore complex in primary cultures of cortical neurons.
Topics: Affinity Labels; Animals; Azides; Benzodiazepines; Cells, Cultured; Cerebral Cortex; Chlorides; Flumazenil; Flunitrazepam; Mice; Mice, Inbred C57BL; Muscimol; Neurons; Receptors, GABA-A | 1994 |
Effects of 5-HT3 receptor antagonists on binding and function of mouse and human GABAA receptors.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Flumazenil; Flunitrazepam; Humans; Indazoles; Indoles; Male; Mice; Mice, Inbred ICR; Receptors, GABA-A; Serotonin Antagonists; Tropanes; Tropisetron; Xenopus laevis | 1994 |
Steroid modulation of GABAA receptors in an amphibian brain.
Topics: Animals; Autoradiography; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Chlorides; Convulsants; Corticosterone; Flunitrazepam; Kinetics; Male; Mammals; Neurons; Pregnanolone; Pregnenolone; Rats; Receptors, GABA-A; Salamandridae; Species Specificity; Steroids; Sulfur Radioisotopes; Synaptosomes; Tritium | 1994 |
Binding characteristics of [3H]flunitrazepam in pentobarbital-withdrawal rats.
Topics: Animals; Cell Membrane; Cerebral Ventricles; Chlorides; Cholic Acids; Flunitrazepam; Frontal Lobe; Infusions, Parenteral; Kinetics; Male; Pentobarbital; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Substance Withdrawal Syndrome; Tritium | 1994 |
beta-Lumicolchicine interacts with the benzodiazepine binding site to potentiate GABAA receptor-mediated currents.
Topics: Animals; Benzodiazepines; Binding Sites; Binding, Competitive; Cerebral Cortex; Chlorides; DNA, Complementary; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Kinetics; Lumicolchicines; Mice; Mice, Inbred ICR; Oocytes; Receptors, GABA-A; Xenopus laevis | 1994 |
GABAergic and dopaminergic transmission in the brain of Roman high-avoidance and Roman low-avoidance rats.
Topics: Amygdala; Animals; Avoidance Learning; Benzazepines; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cerebral Cortex; Chlorides; Convulsants; Corpus Striatum; Dopamine; Emotions; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Kinetics; Male; Nucleus Accumbens; Organ Specificity; Prefrontal Cortex; Rats; Rats, Mutant Strains; Receptors, Dopamine D1; Species Specificity; Synaptic Transmission | 1994 |
Zinc selectively inhibits flux through benzodiazepine-insensitive gamma-aminobutyric acid chloride channels in cortical and cerebellar microsacs.
Topics: Animals; Benzodiazepines; Cerebellum; Cerebral Cortex; Chloride Channels; Chlorides; Chlorine; Drug Synergism; Flumazenil; Flunitrazepam; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Kinetics; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Stimulation, Chemical; Tritium; Zinc | 1993 |
Anticonvulsant doses of 2-chloro-N6-cyclopentyladenosine, an adenosine A1 receptor agonist, reduce GABAergic transmission in different areas of the mouse brain.
Topics: Adenosine; Animals; Anticonvulsants; Behavior, Animal; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Convulsants; Depression, Chemical; Diazepam; Dose-Response Relationship, Drug; Flunitrazepam; gamma-Aminobutyric Acid; Isoniazid; Male; Mice; Mice, Inbred Strains; Purinergic P1 Receptor Antagonists; Receptors, GABA; Receptors, Purinergic P1; Seizures; Sulfur Radioisotopes; Synaptic Transmission; Tritium; Xanthines | 1993 |
Reconstitution of purified GABAA receptors: ligand binding and chloride transporting properties.
Topics: Animals; Bicuculline; Biological Transport; Brain Chemistry; Cattle; Chlorides; Chromatography, Affinity; Dose-Response Relationship, Drug; Flow Injection Analysis; Flunitrazepam; Ligands; Liposomes; Membrane Proteins; Muscimol; Picrotoxin; Quinolinium Compounds; Receptors, GABA-A | 1994 |
GABAA receptor function in the gamma-hydroxybutyrate model of generalized absence seizures.
Topics: Aminocaproates; Animals; Anticonvulsants; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Chlorine; Convulsants; Electroencephalography; Epilepsy, Absence; Flunitrazepam; In Vitro Techniques; Kinetics; Male; Muscimol; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sodium Oxybate; Synaptosomes; Vigabatrin | 1993 |
Neurochemical actions of inhalational anesthetics at the GABAA receptor complex.
Topics: Administration, Inhalation; Animals; Cerebral Cortex; Chlorides; Enflurane; Flunitrazepam; Halothane; Isoflurane; Male; Mice; Receptors, GABA-A | 1993 |
Stereospecific actions of the inhalation anesthetic isoflurane at the GABAA receptor complex.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Flunitrazepam; In Vitro Techniques; Isoflurane; Male; Mice; Receptors, GABA-A; Stereoisomerism; Sulfur Radioisotopes | 1993 |
High-affinity partial agonist imidazo[1,5-a]quinoxaline amides, carbamates, and ureas at the gamma-aminobutyric acid A/benzodiazepine receptor complex.
Topics: Animals; Anxiety; Benzodiazepines; Binding, Competitive; Brain; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Flunitrazepam; GABA Agonists; GABA Antagonists; Molecular Conformation; Molecular Structure; Oxadiazoles; Pentylenetetrazole; Quinoxalines; Rats; Receptors, GABA-A | 1996 |
Microtubule depolymerization inhibits ethanol-induced enhancement of GABAA responses in stably transfected cells.
Topics: Animals; Cattle; Cell Line; Chlorides; Colchicine; Ethanol; Flunitrazepam; Humans; Mice; Microtubules; Muscimol; Pentobarbital; Polymers; Receptor Aggregation; Receptors, GABA-A; Transfection | 1996 |
Characterization of a benzodiazepine receptor site with exceptionally high affinity for Ro 15-4513 in the rat CNS.
Topics: Affinity Labels; Animals; Anti-Anxiety Agents; Azides; Benzodiazepines; Binding Sites; Binding, Competitive; Central Nervous System; Cerebellum; Chlorides; Dose-Response Relationship, Drug; Flumazenil; Flunitrazepam; GABA Modulators; Hippocampus; Imidazoles; Male; Pyridines; Rats; Rats, Wistar; Receptors, GABA-A; Spinal Cord; Tritium | 1995 |
Effect of in vivo administration of anesthetics on GABAA receptor function.
Topics: Anesthesia; Anesthetics; Anesthetics, Inhalation; Animals; Brain; Carbon Dioxide; Chlorides; Ethanol; Flunitrazepam; GABA Modulators; Methoxyflurane; Mice; Mice, Inbred ICR; Pentobarbital; Receptors, GABA | 1996 |
Diazepam physical dependence and withdrawal in rats is associated with alteration in GABAA receptor function.
Topics: Animals; Benzodiazepines; Cerebral Cortex; Chloride Channels; Chlorides; Diazepam; Flumazenil; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; Male; Rats; Rats, Inbred F344; Receptors, GABA-A; Substance Withdrawal Syndrome; Substance-Related Disorders | 1996 |
Is upregulation of benzodiazepine receptors a compensatory reaction to reduced GABAergic tone in the brain of stressed mice?
Topics: Animals; Brain; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Receptors, GABA-A; Stress, Physiological; Thiopental; Up-Regulation | 1996 |
In vivo administration of the 5-HT1A receptor agonist 8-OH-DPAT interferes with brain GABA(A)/benzodiazepine receptor complexes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cerebral Cortex; Chlorides; Diazepam; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; Male; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Synaptosomes | 1997 |
Role of GABA in the actions of ethanol in rats selectively bred for ethanol sensitivity.
Topics: Alcoholic Intoxication; Animals; Behavior, Animal; Central Nervous System Depressants; Chlorides; Ethanol; Female; Flunitrazepam; GABA Agents; gamma-Aminobutyric Acid; Male; Rats; Receptors, GABA; Sleep; Time Factors | 1998 |
Molecular and neurochemical evaluation of the effects of etizolam on GABAA receptors under normal and stress conditions.
Topics: Acetylcholine; Animals; Anti-Anxiety Agents; Binding, Competitive; Chlorides; Diazepam; Electrophysiology; Electroshock; Flunitrazepam; GABA Modulators; Hippocampus; Humans; In Vitro Techniques; Ligands; Male; Microdialysis; Oocytes; Patch-Clamp Techniques; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recombinant Proteins; Stress, Psychological; Xenopus laevis | 1999 |
Fluorescence imaging of GABAA receptor-mediated intracellular [Cl-] in P19-N cells reveals unique pharmacological properties.
Topics: Animals; Central Nervous System Depressants; Chlorides; Diazepam; DNA Primers; Ethanol; Flunitrazepam; Fluorescent Dyes; GABA Agonists; GABA Modulators; Gene Expression; Mice; Muscimol; Neoplastic Stem Cells; Neuroglia; Pentobarbital; Pregnanolone; Quinolinium Compounds; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tritium | 1999 |
The GABA(A) receptor complex as a target for fluoxetine action.
Topics: Animals; Chlorides; Dose-Response Relationship, Drug; Flunitrazepam; Fluoxetine; gamma-Aminobutyric Acid; Ion Transport; Male; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Selective Serotonin Reuptake Inhibitors; Tritium | 1999 |
Effects of treatment with GABA(A) receptor subunit antisense oligodeoxynucleotides on GABA-stimulated 36Cl- influx in the rat cerebral cortex.
Topics: Animals; Base Sequence; Bicuculline; Cerebral Cortex; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; Male; Oligodeoxyribonucleotides, Antisense; Open Reading Frames; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction | 2000 |
Chlordiazepoxide-induced spatial learning deficits: dose-dependent differences following prenatal malnutrition.
Topics: Animals; Anti-Anxiety Agents; Body Weight; Chlordiazepoxide; Chlorides; Dose-Response Relationship, Drug; Female; Flunitrazepam; Gene Expression Regulation, Developmental; Learning Disabilities; Motor Activity; Pregnancy; Pregnancy Complications; Protein Deficiency; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2000 |
[3H]Ro 15-1788 binding sites to brain membrane of the saltwater Mugil cephalus.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Carbolines; Cell Membrane; Chlorides; Diazepam; Female; Fishes; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Imidazoles; Ionophores; Male; Pyridines; Receptors, GABA-A; Synaptosomes; Tritium; Zolpidem | 2001 |
In ovo chronic neurosteroid treatment affects the function and allosteric interactions of GABA(A) receptor modulatory sites.
Topics: Allosteric Regulation; Animals; Chick Embryo; Chloride Channels; Chlorides; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; Ion Transport; Nerve Tissue Proteins; Optic Lobe, Nonmammalian; Pregnanolone; Receptors, GABA-A; Signal Transduction; Specific Pathogen-Free Organisms; Synaptic Membranes; Synaptic Transmission | 2001 |
Activation of GABA(A) receptors in subthalamic neurons in vitro: properties of native receptors and inhibition mechanisms.
Topics: Animals; Bicarbonates; Bicuculline; Chlorides; Diazepam; Electrophysiology; Flunitrazepam; GABA Agonists; GABA Antagonists; GABA Modulators; Membrane Potentials; Muscimol; Neural Inhibition; Neurons; Organ Culture Techniques; Pentobarbital; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Sesterterpenes; Subthalamic Nucleus | 2001 |
Pressure-sensitive and -insensitive coupling in gamma-aminobutyric acid(A) receptors.
Topics: Animals; Atmospheric Pressure; Chlorides; Chlorine; Flunitrazepam; GABA Modulators; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Pentobarbital; Pregnanolone; Radioisotopes; Receptors, GABA-A; Synaptosomes | 2001 |
GABA(A) receptor alpha-1 subunit deletion alters receptor subtype assembly, pharmacological and behavioral responses to benzodiazepines and zolpidem.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Benzodiazepines; Chlorides; Diazepam; Exploratory Behavior; Female; Flunitrazepam; GABA Agonists; GABA Modulators; Gene Deletion; Hypnotics and Sedatives; Male; Mice; Mice, Knockout; Motor Activity; Muscimol; Postural Balance; Pyridines; Radioligand Assay; Receptors, GABA-A; Seizures; Zolpidem | 2002 |
Testosterone treatment induces behavioral disinhibition in adult male rats.
Topics: Androgens; Animals; Behavior, Animal; Central Nervous System Depressants; Chlorides; Dose-Response Relationship, Drug; Drinking; Drug Implants; Electroshock; Ethanol; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; Genitalia, Male; In Vitro Techniques; Inhibition, Psychological; Male; Motivation; Organ Size; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptosomes; Testosterone | 2003 |
Allopregnanolone-stimulated GABA-mediated chloride ion flux is inhibited by 3beta-hydroxy-5alpha-pregnan-20-one (isoallopregnanolone).
Topics: Animals; Cerebral Cortex; Chlorides; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Osmolar Concentration; Pentobarbital; Pregnanolone; Rats; Rats, Wistar | 2003 |
Differential effects of mild repeated restraint stress on behaviors and GABA(A) receptors in male and female rats.
Topics: Animals; Behavior, Animal; Binding, Competitive; Cerebral Cortex; Chlorides; Corticosterone; Female; Flunitrazepam; gamma-Aminobutyric Acid; Male; Maze Learning; Motor Activity; Ovariectomy; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Restraint, Physical; Seizures; Sex Factors; Stress, Psychological; Tritium | 2005 |
Translocator protein (18 kDa) ligand PK 11195 induces transient mitochondrial Ca2+ release leading to transepithelial Cl- secretion in HT-29 human colon cancer cells.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Calcium; Cell Line, Tumor; Chlorides; Colonic Neoplasms; Cyclosporine; Enzyme Inhibitors; Flunitrazepam; GABA Modulators; Gene Expression Regulation, Neoplastic; Humans; Isoquinolines; Ligands; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Neoplasm Proteins; Nitrobenzoates; Receptors, GABA; Sodium-Potassium-Chloride Symporters | 2007 |
Anxiolytic-like effects of obovatol isolated from Magnolia obovata: involvement of GABA/benzodiazepine receptors complex.
Topics: Animals; Anti-Anxiety Agents; Anti-Infective Agents; Anxiety; Biphenyl Compounds; Chlorides; Flunitrazepam; GABA Modulators; Magnolia; Male; Mice; Mice, Inbred ICR; Motor Activity; Phenyl Ethers; Postural Balance; Receptors, GABA-A | 2007 |
6,3'-Dinitroflavone is a low efficacy modulator of GABA(A) receptors.
Topics: Animals; Anti-Anxiety Agents; Cell Line; Chlorides; Female; Flavonoids; Flumazenil; Flunitrazepam; GABA Modulators; Humans; Oocytes; Patch-Clamp Techniques; Protein Binding; Protein Subunits; Receptors, GABA-A; Transfection; Xenopus | 2008 |
Lindane cytotoxicity in cultured neocortical neurons is ameliorated by GABA and flunitrazepam.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cell Survival; Cells, Cultured; Cerebral Cortex; Chloride Channels; Chlorine; Convulsants; Flunitrazepam; gamma-Aminobutyric Acid; Hexachlorocyclohexane; Mice; Neurons; Potassium; Receptors, GABA | 1994 |
[Changes in GABAA/benzodiazepine receptor complex function in the pentobarbital-dependent rat. II: Strain differences between Lewis and Wistar-Kyoto rats].
Topics: Animals; Bicuculline; Brain; Chlorine; Ethanol; Female; Flunitrazepam; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Lew; Rats, Inbred WKY; Receptors, GABA-A; Substance-Related Disorders | 1995 |
Housing conditions alter GABAA receptor of alcohol-preferring and -nonpreferring rats.
Topics: Alcohol Drinking; Animals; Chlorine; Flunitrazepam; gamma-Aminobutyric Acid; Male; Radioisotopes; Rats; Receptors, GABA-A; Social Isolation | 1993 |
Differences in benzodiazepine binding in quail selectively bred for differences in tonic immobility.
Topics: Animals; Anti-Anxiety Agents; Azides; Benzodiazepines; Brain; Chlorine; Coturnix; Diazepam; Ethanol; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Motor Activity; Radioisotopes; Receptors, GABA-A | 1996 |
The enhancement of muscimol-stimulated 36C1 influx by the antispastic 5-aryl-3-(alkylsulfonyl)-4H-1,2,4-triazole (MDL 27,531) in rat brain membrane vesicles.
Topics: Animals; Brain Chemistry; Chloride Channels; Chlorine; Flunitrazepam; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Ion Channel Gating; Male; Membranes; Muscimol; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Triazoles | 1995 |
Effects of the conformationally restricted GABA analogues, cis- and trans-4-aminocrotonic acid, on GABA neurotransmission in primary neuronal cultures.
Topics: Animals; Binding Sites; Cells, Cultured; Cerebellum; Chlorine; Crotonates; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; Neocortex; Rats; Receptors, GABA-A; Receptors, Presynaptic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stereoisomerism | 1999 |
Mechanism-based modeling of functional adaptation upon chronic treatment with midazolam.
Topics: Adaptation, Physiological; Animals; Biological Transport; Brain Chemistry; Chlorine; Dose-Response Relationship, Drug; Electroencephalography; Flunitrazepam; GABA Agonists; GABA Modulators; Male; Midazolam; Models, Biological; Muscimol; Radioligand Assay; Rats; Rats, Wistar; Receptors, GABA-A; Tritium | 2000 |
3Alpha-hydroxy-5alpha-pregnan-20-one levels and GABA(A) receptor-mediated 36Cl(-) flux across development in rat cerebral cortex.
Topics: Allosteric Regulation; Animals; Animals, Newborn; Anti-Anxiety Agents; Biological Transport; Cerebral Cortex; Chlorine; Desoxycorticosterone; Female; Flunitrazepam; GABA Agonists; GABA Modulators; Labor, Obstetric; Male; Muscimol; Pregnancy; Pregnanolone; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sex Characteristics | 2001 |