flunitrazepam and brotizolam

flunitrazepam has been researched along with brotizolam in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19906 (46.15)18.7374
1990's1 (7.69)18.2507
2000's4 (30.77)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Hirouchi, M; Kohno, Y; Kuriyama, K; Mizutani, H1
Bechtel, WD; Ikeda, M; Malatynska, E; Weber, KH; Yamamura, HI1
Danneberg, P1
Bechtel, WD; Ensinger, HA; Mierau, J1
Hare, SA; Sonnenfeld, ED1
Findeisen, P; Goetzke, E; Welbers, IB1
Ahmad, F; Goetzke, E; Köster, J; Rittmeyer, P1
Katoh, H; Ozawa, K; Yoshii, M1
Araki, H; Cui, R; Li, B; Suemaru, K; Tanaka, M; Watanabe, S1
Ameno, K; Jamal, M; Kinoshita, H; Kumihashi, M; Ohkubo, E; Tanaka, N1

Trials

3 trial(s) available for flunitrazepam and brotizolam

ArticleYear
A controlled trial of brotizolam versus flunitrazepam as a hypnotic.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1983, Aug-20, Volume: 64, Issue:8

    Topics: Anti-Anxiety Agents; Azepines; Clinical Trials as Topic; Female; Flunitrazepam; Humans; Hypnotics and Sedatives; Preoperative Care; Random Allocation; Sleep

1983
Efficacy and tolerance: comparative studies with brotizolam and flunitrazepam.
    British journal of clinical pharmacology, 1983, Volume: 16 Suppl 2

    Topics: Adult; Aged; Azepines; Clinical Trials as Topic; Double-Blind Method; Drug Tolerance; Female; Flunitrazepam; Humans; Hypnotics and Sedatives; Male; Middle Aged; Random Allocation; Sleep Wake Disorders

1983
Brotizolam as a pre-operative hypnotic.
    British journal of clinical pharmacology, 1983, Volume: 16 Suppl 2

    Topics: Adolescent; Adult; Aged; Azepines; Clinical Trials as Topic; Double-Blind Method; Drug Tolerance; Female; Flunitrazepam; Humans; Hypnotics and Sedatives; Male; Middle Aged; Premedication; Preoperative Care; Random Allocation

1983

Other Studies

10 other study(ies) available for flunitrazepam and brotizolam

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Characteristics of the association of brotizolam, a thieno-triazolo diazepine derivative, with the benzodiazepine receptor: a selective and high affinity ligand of the central type I benzodiazepine receptor.
    Japanese journal of pharmacology, 1992, Volume: 59, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Azepines; Brain; Dose-Response Relationship, Drug; Flunitrazepam; Hypnotics and Sedatives; In Vitro Techniques; Nitrazepam; Pyridazines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord; Synaptic Membranes; Tritium

1992
Relative efficacies of 1,4-diazepines on GABA-stimulated chloride influx in rat brain vesicles.
    Life sciences, 1989, Volume: 45, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Azepines; Cell Membrane; Cerebral Cortex; Chlorides; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1989
Effects of brotizolam and other diazepines on respiration.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:3A

    Topics: Anesthesia; Animals; Anti-Anxiety Agents; Azepines; Cats; Chloralose; Female; Flunitrazepam; Hypnotics and Sedatives; Male; Respiration; Triazolam; Urethane

1986
Biochemical studies with the new thienotriazolo-diazepine brotizolam.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:3A

    Topics: Animals; Azepines; Binding, Competitive; Biogenic Amines; Diazepam; Dopamine; Flunitrazepam; Homovanillic Acid; Hypnotics and Sedatives; In Vitro Techniques; Male; Rats; Receptors, Drug; Receptors, GABA-A; Synaptosomes

1986
[Comparative study of drug efficacy and drug additives between generic drugs and original drugs].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2007, Volume: 127, Issue:12

    Topics: Adjuvants, Pharmaceutic; Animals; Azepines; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drugs, Generic; Flunitrazepam; Hypnotics and Sedatives; Male; Mice; Therapeutic Equivalency; Triazolam

2007
Behavioral pharmacological properties after recovery from the loss of righting reflex induced by benzodiazepine receptor agonists in mice.
    Methods and findings in experimental and clinical pharmacology, 2008, Volume: 30, Issue:8

    Topics: Animals; Azepines; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Flunitrazepam; GABA Agonists; GABA-A Receptor Agonists; Hypnotics and Sedatives; Ketanserin; Male; Mice; Mice, Inbred Strains; Pyridines; Reflex; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Time Factors; Zolpidem

2008
A case of drowning whilst under the influence of brotizolam, flunitrazepam and ethanol.
    Soudni lekarstvi, 2011, Volume: 56, Issue:1

    Topics: Aged; Alcoholic Intoxication; Anti-Anxiety Agents; Azepines; Central Nervous System Depressants; Drowning; Drug Overdose; Ethanol; Female; Flunitrazepam; Forensic Medicine; Humans; Hypnotics and Sedatives

2011