flunitrazepam has been researched along with alprazolam in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (26.32) | 18.7374 |
| 1990's | 3 (15.79) | 18.2507 |
| 2000's | 7 (36.84) | 29.6817 |
| 2010's | 3 (15.79) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Li, Y; Li, YH; Wang, YH; Yang, L; Yang, SL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Ahmed, T; Cook, JM; Golani, LK; Mondal, P; Pandey, KP; Rezvanian, S; Sharmin, D; Witkin, JM; Yeunus Mian, M | 1 |
| Beck, O; Borg, S; Hjemdahl, P; Lafolie, P; Odelius, G; Wirbing, P | 1 |
| Clow, A; Glover, V; Sandler, M | 1 |
| Cho, MJ; Haynes, LC; Sethy, VH | 1 |
| Harris, DW; Sethy, VH | 2 |
| Jenck, F; Martin, JR; Moreau, JL | 1 |
| Hemmersbach, P; Ragnar Norli, H; Rasmussen, KE; Reubsaet, KJ | 1 |
| Cook, JM; Lelas, S; Rowlett, JK; Spealman, RD; Yin, W | 1 |
| Loscalzo, LM; Marder, M; Paladini, AC; Wasowski, C | 1 |
| Galetin, A; Hallifax, D; Houston, JB | 1 |
| Marchi, I; Rudaz, S; Schappler, J; Veuthey, JL | 1 |
| Gunn, J; Kriger, S; Terrell, AR | 1 |
| Constantino, L; Dias, C; Dias, M; Soveral, G; Testa, B | 1 |
19 other study(ies) available for flunitrazepam and alprazolam
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism.
Topics: Computational Biology; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Molecular Structure; Principal Component Analysis; Pyrrolizidine Alkaloids; Quantitative Structure-Activity Relationship; Reproducibility of Results; Substrate Specificity; Venlafaxine Hydrochloride | 2005 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
Rationalizing the binding and α subtype selectivity of synthesized imidazodiazepines and benzodiazepines at GABAA receptors by using molecular docking studies.
Topics: Alprazolam; Benzodiazepines; Chlorine; Diazepam; gamma-Aminobutyric Acid; Ion Channels; Ligands; Molecular Docking Simulation; Receptors, GABA; Receptors, GABA-A | 2022 |
Detection of benzodiazepine intake in therapeutic doses by immunoanalysis of urine: two techniques evaluated and modified for improved performance.
Topics: Adult; Alprazolam; Benzodiazepines; Chlordiazepoxide; False Negative Reactions; Flunitrazepam; Fluorescence Polarization Immunoassay; Humans; Immunoenzyme Techniques; Lorazepam; Male; Middle Aged; Nitrazepam; Triazolam | 1992 |
Triazolam, an anomalous benzodiazepine receptor ligand: in vitro characterization of alprazolam and triazolam binding.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Carbolines; Clonazepam; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Triazolam | 1985 |
Sequentially labile water-soluble prodrugs of alprazolam.
Topics: Alprazolam; Animals; Benzodiazepines; Binding, Competitive; Blood; Brain; Dosage Forms; Female; Flunitrazepam; Humans; Hydrolysis; In Vitro Techniques; Male; Mice; Receptors, GABA-A; Solubility; Water | 1986 |
Determination of biological activity of alprazolam, triazolam and their metabolites.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Benzodiazepines; Binding, Competitive; Brain; Diazepam; Flunitrazepam; Kinetics; Male; Membranes; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, GABA-A; Triazolam | 1982 |
Benzodiazepine receptor number after acute administration of alprazolam and diazepam.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Benzodiazepines; Binding, Competitive; Brain; Diazepam; Flunitrazepam; In Vitro Techniques; Kinetics; Male; Membranes; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, GABA-A | 1982 |
Three more benzodiazepines.
Topics: Alprazolam; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Bromazepam; Flunitrazepam; Humans; Sleep Initiation and Maintenance Disorders | 1983 |
Precipitated withdrawal in squirrel monkeys after repeated daily oral administration of alprazolam, diazepam, flunitrazepam or oxazepam.
Topics: Administration, Oral; Alprazolam; Animals; Behavior, Animal; Diazepam; Dose-Response Relationship, Drug; Drug Tolerance; Female; Flumazenil; Flunitrazepam; Male; Muscle Relaxation; Oxazepam; Saimiri; Sleep; Substance Withdrawal Syndrome; Substance-Related Disorders; Tremor | 1995 |
Determination of benzodiazepines in human urine and plasma with solvent modified solid phase micro extraction and gas chromatography; rationalisation of method development using experimental design strategies.
Topics: Alprazolam; Anti-Anxiety Agents; Benzodiazepines; Chromatography, Gas; Diazepam; Flunitrazepam; Humans; Hydrogen-Ion Concentration; Models, Chemical; Nordazepam; Oxazepam; Research Design | 1998 |
Discriminative stimulus effects of zolpidem in squirrel monkeys: role of GABA(A)/alpha1 receptors.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Benzodiazepines; Carbolines; Discrimination Learning; Dose-Response Relationship, Drug; Flunitrazepam; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; Injections, Intravenous; Male; Pyridazines; Pyridines; Receptors, GABA-A; Saimiri; Zolpidem | 2003 |
Opioid receptors are involved in the sedative and antinociceptive effects of hesperidin as well as in its potentiation with benzodiazepines.
Topics: Acetic Acid; Alprazolam; Analgesics; Animals; Behavior, Animal; Benzodiazepines; Dose-Response Relationship, Drug; Drug Synergism; Flunitrazepam; Hesperidin; Hypnotics and Sedatives; Injections, Intraperitoneal; Male; Mice; Morphine; Motor Activity; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Receptors, Opioid | 2008 |
Prediction of metabolic clearance using fresh human hepatocytes: comparison with cryopreserved hepatocytes and hepatic microsomes for five benzodiazepines.
Topics: Alprazolam; Benzodiazepines; Cell Survival; Cells, Cultured; Cryopreservation; Cytochrome P-450 CYP3A; Diazepam; Flunitrazepam; Hepatocytes; Humans; Metabolic Clearance Rate; Microsomes, Liver; Midazolam; Substrate Specificity; Triazolam | 2008 |
Development and validation of a liquid chromatography-atmospheric pressure photoionization-mass spectrometry method for the quantification of alprazolam, flunitrazepam, and their main metabolites in haemolysed blood.
Topics: Alprazolam; Anti-Anxiety Agents; Chromatography, Liquid; Flunitrazepam; Humans; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2009 |
Simultaneous determination and quantification of 12 benzodiazepines in serum or whole blood using UPLC/MS/MS.
Topics: Alprazolam; Benzodiazepines; Chlordiazepoxide; Chromatography, Liquid; Clonazepam; Flunitrazepam; Humans; Lorazepam; Midazolam; Nordazepam; Oxazepam; Reproducibility of Results; Tandem Mass Spectrometry | 2010 |
Screening of the inhibitory effect of xenobiotics on alcohol metabolism using S9 rat liver fractions.
Topics: Alcohol Dehydrogenase; Alprazolam; Animals; Cimetidine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Ethanol; Flunitrazepam; Fomepizole; Inhibitory Concentration 50; Liver; Pyrazoles; Rats; Rats, Wistar; Ribosomal Protein S9; Ribosomal Proteins; Tramadol; Xenobiotics | 2012 |