flumazenil has been researched along with zopiclone in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (38.71) | 18.7374 |
| 1990's | 5 (16.13) | 18.2507 |
| 2000's | 9 (29.03) | 29.6817 |
| 2010's | 5 (16.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Byrnes, JJ; Greenblatt, DJ; Miller, LG | 1 |
| Blanchard, JC; Boireau, A; Doble, A; Dubedat, P; Laduron, PM | 1 |
| Ahmad, Z; Ebden, P; Herepath, M | 1 |
| Kumasaka, Y; Ueki, S; Yamamoto, T | 1 |
| Nagatani, T; Sugihara, T; Ueki, S; Yamamoto, T | 1 |
| Barrett, JE; Brady, LS; Mansbach, RS; Stanley, JA; Witkin, JM | 1 |
| Ator, NA; Griffiths, RR | 1 |
| Spealman, RD; Wettstein, JG | 2 |
| Ueki, S; Yamamoto, T | 1 |
| Spealman, RD | 1 |
| Ferrario, P; Hafner, B; Mantegazza, P; Zambotti, F; Zecca, L; Zonta, N | 1 |
| Conci, F; Ferrario, P; Hafner, B; Mantegazza, P; Tammiso, R; Zambotti, F; Zecca, L; Zonta, N | 1 |
| Macdonald, RL; Skerritt, JH | 1 |
| Goldberg, ME; Malick, JB; Patel, JB; Salama, AI | 1 |
| Biggio, G; Concas, A; Cuccheddu, T; Maciocco, E; Santoro, G; Serra, M | 1 |
| Carter, DB; Hamilton, BJ; Im, HK; Im, WB; Vonvoigtlander, PF | 1 |
| Cuparencu, B; Horák, A; Horák, J | 1 |
| Paz, L; Peter, Y; Pick, CG; Toren, P; Weizman, R | 1 |
| France, CP; Jerussi, TP; McMahon, LR | 1 |
| Haga, C | 1 |
| Burkhart, KK; Cienki, JJ; Donovan, JW | 1 |
| Deng, JF; Yang, CC | 1 |
| Allen, MS; Brian Nofsinger, J; Hopkins, SC; Koch, P; Varney, MA | 1 |
| Gunja, N | 1 |
| Cimolai, N | 1 |
2 review(s) available for flumazenil and zopiclone
| Article | Year |
|---|---|
Novel non-benzodiazepine anxiolytics.
Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Benzodiazepines; Benzodiazepinones; Conflict, Psychological; Flumazenil; Flunitrazepam; Hypnotics and Sedatives; Mice; Piperazines; Pyrazoles; Pyridazines; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
The clinical and forensic toxicology of Z-drugs.
Topics: Acetamides; Azabicyclo Compounds; Coma; Drug Overdose; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; Humans; Hypnotics and Sedatives; Piperazines; Pyridines; Pyrimidines; Zolpidem | 2013 |
29 other study(ies) available for flumazenil and zopiclone
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Benzodiazepine receptor binding of nonbenzodiazepines in vivo: alpidem, zolpidem and zopiclone.
Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Brain; Cerebellum; Cerebral Cortex; Dose-Response Relationship, Drug; Flumazenil; Hippocampus; Hypnotics and Sedatives; Imidazoles; Male; Mice; Mice, Inbred Strains; Piperazines; Pyridines; Receptors, GABA-A; Reference Values; Zolpidem | 1992 |
Preferential decrease in dopamine utilization in prefrontal cortex by zopiclone, diazepam and zolpidem in unstressed rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Azabicyclo Compounds; Cerebral Cortex; Corpus Striatum; Diazepam; Dopamine; Flumazenil; Male; Piperazines; Pyridines; Rats; Rats, Inbred Strains; Stress, Physiological; Zolpidem | 1990 |
Diagnostic utility of flumazenil in coma with suspected poisoning.
Topics: Azabicyclo Compounds; Coma; Flumazenil; Humans; Hypnotics and Sedatives; Male; Middle Aged; Piperazines; Suicide, Attempted | 1991 |
Behavioral analysis of zopiclone on the basis of their discriminative stimulus properties in the rat.
Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Behavior, Animal; Benzodiazepines; Bicuculline; Discrimination Learning; Dose-Response Relationship, Drug; Flumazenil; Hypnotics and Sedatives; Male; Muscimol; Naphthyridines; Pentylenetetrazole; Piperazines; Piperidines; Rats; Rats, Inbred WKY; Ritanserin; Serotonin Antagonists; Sulfur Compounds | 1989 |
The effect of agonists at the GABA-benzodiazepine-receptor-complex on the proconflict effect induced by beta-CCM and pentetrazol in rats.
Topics: Aminooxyacetic Acid; Animals; Azabicyclo Compounds; Carbolines; Conflict, Psychological; Convulsants; Diazepam; Flumazenil; Hypnotics and Sedatives; Male; Pentylenetetrazole; Phenobarbital; Piperazines; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1988 |
Behavioral studies with anxiolytic drugs. II. Interactions of zopiclone with ethyl-beta-carboline-3-carboxylate and Ro 15-1788 in squirrel monkeys.
Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Behavior, Animal; Benzodiazepinones; Carbolines; Chlordiazepoxide; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Female; Flumazenil; Food; Male; Piperazines; Punishment; Receptors, GABA-A; Saimiri | 1986 |
Discriminative stimulus effects of atypical anxiolytics in baboons and rats.
Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Benzodiazepinones; Buspirone; Discrimination Learning; Flumazenil; Isoxazoles; Lorazepam; Male; Papio; Piperazines; Pyrazoles; Pyridazines; Pyrimidines; Quinolines; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1986 |
Behavioral effects of zopiclone, CL 218,872 and diazepam in squirrel monkeys: antagonism by Ro 15-1788 and CGS 8216.
Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Benzodiazepinones; Conditioning, Operant; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Male; Piperazines; Pyrazoles; Pyridazines; Saimiri | 1986 |
A new method for screening anxiolytic drugs in rats.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Azabicyclo Compounds; Diazepam; Drug Evaluation, Preclinical; Flumazenil; Male; Models, Psychological; Piperazines; Rats; Rats, Inbred WKY | 1987 |
Discriminative-stimulus effects of midazolam in squirrel monkeys: comparison with other drugs and antagonism by Ro 15-1788.
Topics: Animals; Azabicyclo Compounds; Barbital; Benzodiazepines; Benzodiazepinones; Buspirone; Caffeine; Chlordiazepoxide; Cinanserin; Clozapine; Conditioning, Operant; Cyproheptadine; Diazepam; Diphenhydramine; Discrimination Learning; Electroshock; Flumazenil; Male; Midazolam; Muscimol; Nordazepam; Pentobarbital; Piperazines; Pyridazines; Pyrimidines; Saimiri; Tripelennamine | 1985 |
Behavioral effects of the pyrazoloquinoline CGS 9896: agonist and antagonist actions in squirrel monkeys.
Topics: Animals; Azabicyclo Compounds; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Flumazenil; Lorazepam; Male; Piperazines; Pyrazoles; Saimiri | 1987 |
Modification of GABA turnover in the striatum and hippocampus of the rat after zopiclone.
Topics: Aminooxyacetic Acid; Animals; Azabicyclo Compounds; Benzodiazepinones; Corpus Striatum; Flumazenil; gamma-Aminobutyric Acid; Hippocampus; Hypnotics and Sedatives; Kinetics; Male; Piperazines; Rats; Rats, Inbred Strains | 1987 |
Zopiclone potentiates the antinociceptive effect of morphine in rats.
Topics: Animals; Azabicyclo Compounds; Benzodiazepines; Benzodiazepinones; Drug Synergism; Flumazenil; Hypnotics and Sedatives; Male; Morphine; Pain; Pain Measurement; Piperazines; Rats; Rats, Inbred Strains; Sensory Thresholds | 1987 |
Benzodiazepine receptor ligand actions on GABA responses. Benzodiazepines, CL 218872, zopiclone.
Topics: Animals; Azabicyclo Compounds; Benzodiazepines; Benzodiazepinones; Cells, Cultured; Drug Interactions; Flumazenil; gamma-Aminobutyric Acid; Ligands; Mice; Neurons; Piperazines; Pyridazines; Receptors, Cell Surface; Receptors, GABA-A; Spinal Cord | 1984 |
The effect of cyclopyrrolones on GABAA receptor function is different from that of benzodiazepines.
Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Benzodiazepines; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorides; Chlorine; Flumazenil; Hypnotics and Sedatives; Kinetics; Male; Mice; Mice, Inbred Strains; Muscimol; Naphthyridines; Piperazines; Radioisotopes; Receptors, GABA-A; Sulfur Compounds; Sulfur Radioisotopes; Tritium | 1994 |
Potentiation of gamma-aminobutyric acid-induced chloride currents by various benzodiazepine site agonists with the alpha 1 gamma 2, beta 2 gamma 2 and alpha 1 beta 2 gamma 2 subtypes of cloned gamma-aminobutyric acid type A receptors.
Topics: Anti-Anxiety Agents; Azabicyclo Compounds; Benzodiazepines; Binding Sites; Cells, Cultured; Chloride Channels; Cloning, Molecular; Drug Synergism; Flumazenil; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Imidazoles; Kidney; Kinetics; Membrane Potentials; Piperazines; Pyridazines; Pyridines; Receptors, GABA-A; Triazolam | 1993 |
Acute effects of zopiclone on blood glucose level and serum lipids in hyperlipidemic rats. Interactions with PK 11195 and flumazenil.
Topics: Animals; Azabicyclo Compounds; Blood Glucose; Central Nervous System; Cholesterol; Flumazenil; GABA Modulators; Hyperlipidemias; Hypnotics and Sedatives; Isoquinolines; Lipids; Male; Peripheral Nervous System; Piperazines; Polyethylene Glycols; Rats; Rats, Wistar; Receptors, GABA-A; Triglycerides | 2000 |
Behavioral effects of agents active at the gamma-aminobutyric acid receptor complex in the staircase paradigm.
Topics: Acetates; Adjuvants, Immunologic; Amines; Animals; Anti-Anxiety Agents; Anxiety; Azabicyclo Compounds; Behavior, Animal; Brain; Clonazepam; Cyclohexanecarboxylic Acids; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Exploratory Behavior; Flumazenil; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Mice; Mice, Inbred ICR; Motor Activity; Neurons; Piperazines; Receptors, GABA-A | 2001 |
Stereoselective discriminative stimulus effects of zopiclone in rhesus monkeys.
Topics: Administration, Oral; Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Modulators; GABA-A Receptor Antagonists; Macaca mulatta; Male; Midazolam; Piperazines; Stereoisomerism; Substance Withdrawal Syndrome | 2003 |
[Poisonings with benzodiazepine-like drugs].
Topics: Acetamides; Antidotes; Azabicyclo Compounds; Flumazenil; Humans; Hypnotics and Sedatives; Norway; Piperazines; Poisoning; Pyridines; Pyrimidines; Zolpidem | 2003 |
Zopiclone overdose responsive to flumazenil.
Topics: Adult; Antidotes; Azabicyclo Compounds; Bradycardia; Central Nervous System Depressants; Charcoal; Chromatography, Liquid; Electrocardiography; Flumazenil; Humans; Male; Piperazines; Suicide, Attempted | 2005 |
Utility of flumazenil in zopiclone overdose.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidotes; Azabicyclo Compounds; Drug Overdose; Female; Flumazenil; GABA Modulators; Humans; Hypnotics and Sedatives; Male; Middle Aged; Piperazines; Retrospective Studies; Suicide, Attempted; Young Adult | 2008 |
In vivo saturation binding of GABA-A receptor ligands to estimate receptor occupancy using liquid chromatography/tandem mass spectrometry.
Topics: Algorithms; Animals; Azabicyclo Compounds; Binding Sites; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Flumazenil; Fluorobenzenes; GABA Agonists; GABA Modulators; Hypnotics and Sedatives; In Vitro Techniques; Indicators and Reagents; Ligands; Male; Mice; Models, Statistical; Piperazines; Pyridines; Receptors, GABA-A; Stereoisomerism; Tandem Mass Spectrometry; Triazoles; Zolpidem | 2009 |
Zopiclone overdose and flumazenil rescue.
Topics: Azabicyclo Compounds; Benzodiazepines; Drug Overdose; Flumazenil; Humans; Piperazines | 2017 |