flumazenil and vigabatrin

flumazenil has been researched along with vigabatrin in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's2 (18.18)18.2507
2000's4 (36.36)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, EA; Kaminsky-Russ, K; Martin, JV; Mendelson, WB; Mullen, KD1
Porter, RJ1
Bottlaender, M; Brouillet, E; Fuseau, C; Mazière, M; Schmid, L1
Fujita, M; Hyder, F; Innis, RB; Mattson, RH; Petroff, OA; Rajeevan, N; Rothman, DL; Seibyl, JP; Verhoeff, NP; Zoghbi, SS1
Jutila, L; Kälviäinen, R; Lamusuo, S; Lehikoinen, P; Någren, K; Oikonen, V; Partanen, K; Pitkänen, A; Rinne, JO; Ruottinen, HM; Vainio, P; Vapalahti, M; Ylinen, A1
Adamec, RE1
Chugani, DC; Chugani, HT; Janisse, J; Juhász, C; Muzik, O; Shen, C1

Reviews

1 review(s) available for flumazenil and vigabatrin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for flumazenil and vigabatrin

ArticleYear
[11 C]Flumazenil binding in the medial temporal lobe in patients with temporal lobe epilepsy: correlation with hippocampal MR volumetry, T2 relaxometry, and neuropathology.
    Neurology, 2000, Jun-27, Volume: 54, Issue:12

    Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepines; Epilepsy, Temporal Lobe; Female; Flumazenil; GABA Modulators; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Temporal Lobe; Tomography, Emission-Computed; Treatment Outcome; Valproic Acid; Vigabatrin

2000

Other Studies

9 other study(ies) available for flumazenil and vigabatrin

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Evidence for the presence of a benzodiazepine receptor binding substance in cerebrospinal fluid of a rabbit model of hepatic encephalopathy.
    Metabolic brain disease, 1989, Volume: 4, Issue:4

    Topics: Aminocaproates; Animals; Binding, Competitive; Flumazenil; GABA-A Receptor Antagonists; Galactosamine; Hepatic Encephalopathy; Hypoxanthine; Hypoxanthines; Male; Rabbits; Radioligand Assay; Receptors, GABA-A; Vigabatrin

1989
Mechanisms of action of new antiepileptic drugs.
    Epilepsia, 1989, Volume: 30 Suppl 1

    Topics: Acetamides; Acetates; Amines; Aminocaproates; Aminopyridines; Anti-Anxiety Agents; Anticonvulsants; Aspartic Acid; Benzodiazepines; Benzodiazepinones; Clobazam; Cyclohexanecarboxylic Acids; Dibenzocycloheptenes; Dizocilpine Maleate; Epilepsy; Felbamate; Flumazenil; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Imidazoles; Lamotrigine; Phenylcarbamates; Propylene Glycols; Receptors, GABA-A; Triazines; Vigabatrin

1989
Vigabatrin modulates benzodiazepine receptor activity in vivo: a positron emission tomography study in baboon.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 276, Issue:3

    Topics: Animals; Diazepam; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flumazenil; gamma-Aminobutyric Acid; Linear Models; Male; Papio; Radioligand Assay; Receptors, GABA-A; Tomography, Emission-Computed; Vigabatrin

1996
Effects of vigabatrin on the GABAergic system as determined by [123I]iomazenil SPECT and GABA MRS.
    Epilepsia, 1999, Volume: 40, Issue:10

    Topics: Adult; Anticonvulsants; Female; Flumazenil; Humans; Iodine Radioisotopes; Magnetic Resonance Spectroscopy; Male; Middle Aged; Occipital Lobe; Receptors, GABA; Tomography, Emission-Computed, Single-Photon; Vigabatrin

1999
Evidence that long-lasting potentiation of amygdala efferents in the right hemisphere underlies pharmacological stressor (FG-7142) induced lasting increases in anxiety-like behaviour: role of GABA tone in initiation of brain and behavioural changes.
    Journal of psychopharmacology (Oxford, England), 2000, Volume: 14, Issue:4

    Topics: Aggression; Amygdala; Animals; Anticonvulsants; Anxiety; Behavior, Animal; Brain Chemistry; Carbolines; Cats; Efferent Pathways; Flumazenil; Functional Laterality; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Hypothalamus, Middle; Male; Predatory Behavior; Rats; Receptors, GABA-A; Stress, Psychological; Vigabatrin; Vocalization, Animal

2000
Prolonged vigabatrin treatment modifies developmental changes of GABA(A)-receptor binding in young children with epilepsy.
    Epilepsia, 2001, Volume: 42, Issue:10

    Topics: Age Factors; Brain; Brain Mapping; Carbon Radioisotopes; Child; Child, Preschool; Epilepsy; Female; Flumazenil; Humans; Infant; Male; Neuronal Plasticity; Radioligand Assay; Receptors, GABA-A; Tomography, Emission-Computed; Vigabatrin

2001