flumazenil has been researched along with ro 5-4864 in 69 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 41 (59.42) | 18.7374 |
| 1990's | 21 (30.43) | 18.2507 |
| 2000's | 4 (5.80) | 29.6817 |
| 2010's | 3 (4.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bendinelli, S; Castellano, S; Cosconati, S; Costa, B; Da Pozzo, E; Da Settimo, F; Greco, G; Martini, C; Milite, C; Novellino, E; Pugliesi, I; Rizzetto, E; Sbardella, G; Stefancich, G; Taliani, S | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Järvinen, A; Männistö, PT; Rägo, L | 1 |
| Bitran, D; Ison, JR; Kellogg, CK; Sullivan, AT | 1 |
| Da-Cunha, C; Ferreira, MB; Izquierdo, I; Jerusalinsky, D; Medina, JH; Wolfman, C | 1 |
| Izquierdo, I; Medina, JH; Pereira, ME | 1 |
| Elgoyhen, AB; Kazanietz, MG | 1 |
| Knudsen, J; Nielsen, M | 1 |
| Berkovich, A; Campagnone, M; Guidotti, A; Hensley, P; McPhie, P | 1 |
| Hashemi, FS; Niles, LP | 1 |
| Adler-Graschinsky, E; Elgoyhen, B | 1 |
| Brouillet, E; Chavoix, C; de la Sayette, V; Dodd, RH; Fournier, D; Guibert, B; Hantraye, P; Khalili-Varasteh, M; Kunimoto, M; Naquet, R | 1 |
| Griffin, K; Hong, T; Levy, JV | 1 |
| Chiesi, M; Erne, P; Fulbright, J; Hermsmeyer, K; Longoni, S | 1 |
| Berg, DK; McEachern, AE | 1 |
| Daval, JL; Deckert, J; Marangos, PJ; Morgan, PF; Nakajima, T | 1 |
| File, SE; Pellow, S | 5 |
| Casals-Stenzel, J; Weber, KH | 1 |
| O'Regan, MH; Phillis, JW | 1 |
| Dubroeucq, MC; Gauthier, A; Guérémy, C; Le Fur, G; Mizoule, J; Renault, C; Uzan, A | 1 |
| Consolo, S; Forloni, G; Garattini, S; Kolasa, K; Ladinsky, H | 1 |
| Cooper, SJ; Gilbert, DB | 1 |
| Abraham, CJ; De Blas, AL; Haney, SA; Park, D; Rayner, CA; Sangameswaran, L | 1 |
| Cole, R; De Vellis, J; Noble, EP; Syapin, PJ | 1 |
| Fares, F; Gavish, M | 1 |
| Basile, AS; Skolnick, P | 1 |
| Simmonds, MA | 1 |
| Lingjaerde, O | 1 |
| Lucantoni, D; Massotti, M | 1 |
| Bryere, P; Naquet, R; Valin, A | 1 |
| Kunert-Radek, J; Pawlikowski, M; Stepień, H | 2 |
| Lafaille, F; Lal, S; Nair, NP; Quirion, R; Suranyi-Cadotte, B | 1 |
| Kulkarni, SK; Kunchandy, J | 1 |
| Teo, WL; Wong, PT | 1 |
| Glushakov, PG | 1 |
| Kunert-Radek, J; Pawlikowski, M; Radek, A; Stepien, H | 1 |
| Belin, C; Carriot, T; Dubroeucq, MC; Guérémy, C; Le Fur, G; Mestre, M; Renault, C; Uzan, A | 1 |
| Brown, C; Martin, IL | 1 |
| Phillis, JW | 1 |
| Chen Chow, S; Davies, LP; Johnston, GA; Skerritt, JH | 1 |
| Garattini, S; Mennini, T | 1 |
| File, SE; Green, AR; Nutt, DJ; Vincent, ND | 1 |
| Coffin, VL; Phillis, JW; Wu, PH | 1 |
| Lloyd, HG; Morgan, PF; Stone, TW | 1 |
| Ramanjaneyulu, R; Ticku, MK | 1 |
| Hirsch, JD | 1 |
| Cuparencu, B; Horák, J | 1 |
| Antonenko, YN; Kinnally, KW; McEnery, MW; Snyder, SH; Tedeschi, H; Zorov, DB | 1 |
| Chen, JS; Gee, KW; Johnson, D; Lan, NC | 1 |
| Matthews, EK; Ratcliffe, SL | 1 |
| Chang, CC; Chiou, LC | 1 |
| Lichtensteiger, W; Ramseier, H; Schlumpf, M | 1 |
| Neu, JM; Niles, LP; Tenn, CC | 1 |
| Cespuglio, R; Miachon, S | 1 |
| Leeuwin, RS; van Hamme, J; van Wilgenburg, H; Zeegers, A | 1 |
| Kulkarni, SK; Reddy, DS | 1 |
| Katukov, VIu; Lesnichuk, SA; Porodenko, NV; Severin, ES | 1 |
| Kawaguchi, M; Okubo, M | 1 |
| Bender, AS; Norenberg, MD | 1 |
| Kaur, G; Kulkarni, SK; Raghavendra, V | 1 |
| Bruni, F; Ciciani, G; Costa, B; Costagli, C; Costanzo, A; Guerrini, G; Martini, C; Selleri, S | 1 |
| Biggio, G; Latrofa, A; Papi, G; Pisu, MG; Porcu, P; Serra, M; Trapani, G | 1 |
| Dehne, MG; Engel, J; Fuchs, M; Gonter, J; Hempelmann, G; Krüll, M; Matejec, R; Menges, T; Mühling, J; Nickolaus, KA; Sablotzki, A; Welters, ID; Wolff, M | 1 |
| Chen, SL; Liu, XG; Wei, XH; Zang, Y; Zheng, WH | 1 |
5 review(s) available for flumazenil and ro 5-4864
| Article | Year |
|---|---|
Memory modulation by brain benzodiazepines.
Topics: Animals; Avoidance Learning; Benzodiazepines; Benzodiazepinones; Brain; Brain Chemistry; Convulsants; Down-Regulation; Flumazenil; Habituation, Psychophysiologic; Memory; Muscimol; Rats | 1991 |
The role of adenosine in the central actions of the benzodiazepines.
Topics: Adenosine; Animals; Anti-Anxiety Agents; Arousal; Benzodiazepinones; Brain; Carbolines; Diazepam; Flumazenil; gamma-Aminobutyric Acid; Neural Inhibition; Neurons; Purkinje Cells; Rats; Receptors, GABA-A | 1988 |
Behavioural actions of Ro 5-4864: a peripheral-type benzodiazepine?
Topics: Animals; Behavior, Animal; Benzodiazepinones; Binding Sites; Brain; Convulsants; Drug Interactions; Flumazenil; Humans; Isoquinolines; Kidney; Phenytoin; Picrotoxin; Pyrazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1984 |
Multiple sites of action for anxiogenic drugs: behavioural, electrophysiological and biochemical correlations.
Topics: Action Potentials; Animals; Anxiety; Behavior, Animal; Benzodiazepinones; Binding Sites; Brain Chemistry; Carbolines; Cats; Flumazenil; Humans; Mice; Rats; Receptors, GABA-A | 1984 |
Adenosine's role in the central actions of the benzodiazepines.
Topics: Adenosine; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepinones; Brain; Cats; Cell Line; Cerebral Cortex; Diazepam; Flumazenil; Rats; Synaptosomes; Thioinosine | 1984 |
64 other study(ies) available for flumazenil and ro 5-4864
| Article | Year |
|---|---|
Synthesis and biological evaluation of 4-phenylquinazoline-2-carboxamides designed as a novel class of potent ligands of the translocator protein.
Topics: Animals; Binding, Competitive; Carrier Proteins; Cell Line, Tumor; Cell Survival; Inhibitory Concentration 50; Molecular Structure; Quinazolines; Rats; Receptors, GABA-A; Structure-Activity Relationship | 2012 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Effects of central and peripheral type benzodiazepine ligands on thyrotropin and prolactin secretion.
Topics: Animals; Benzodiazepinones; Carbolines; Clonazepam; Cold Temperature; Diazepam; Flumazenil; Hypothalamo-Hypophyseal System; Isoquinolines; Male; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Secretory Rate; Thyrotropin; Thyrotropin-Releasing Hormone | 1992 |
Modulation of noise-potentiated acoustic startle via the benzodiazepine--gamma-aminobutyric acid receptor complex.
Topics: Acoustic Stimulation; Animals; Auditory Perception; Benzodiazepinones; Brain; Convulsants; Diazepam; Flumazenil; GABA-A Receptor Antagonists; Male; Neurons; Rats; Receptors, GABA-A; Reflex, Startle | 1991 |
Benzodiazepine receptor ligand influences on acquisition: suggestion of an endogenous modulatory mechanism mediated by benzodiazepine receptors.
Topics: Animals; Anti-Anxiety Agents; Arousal; Avoidance Learning; Benzodiazepinones; Brain; Carbolines; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Exploratory Behavior; Female; Flumazenil; Habituation, Psychophysiologic; Memory; Mental Recall; Rats; Rats, Inbred Strains; Reaction Time; Receptors, GABA-A; Retention, Psychology | 1990 |
Relaxant effect of benzodiazepines on uterine rings isolated from estrogen-treated rats.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Bicuculline; Clonazepam; Convulsants; Diazepam; Estradiol; Estrogens; Female; Flumazenil; In Vitro Techniques; Isoquinolines; Muscle, Smooth; Potassium Chloride; Propranolol; Rats; Rats, Inbred Strains; Uterine Contraction | 1990 |
Diazepam-binding inhibitor: a neuropeptide and/or an acyl-CoA ester binding protein?
Topics: Acyl Coenzyme A; Adrenal Cortex; Amino Acid Sequence; Animals; Benzodiazepinones; Brain; Carboxylic Acids; Carrier Proteins; Cattle; Diazepam; Diazepam Binding Inhibitor; Esters; Flumazenil; Liver; Molecular Sequence Data; Nerve Tissue Proteins; Neuropeptides; Peptide Fragments; Rats | 1990 |
A natural processing product of rat diazepam binding inhibitor, triakontatetraneuropeptide (diazepam binding inhibitor 17-50) contains an alpha-helix, which allows discrimination between benzodiazepine binding site subtypes.
Topics: Amino Acid Sequence; Animals; Benzodiazepinones; Binding, Competitive; Circular Dichroism; Flumazenil; In Vitro Techniques; Models, Molecular; Molecular Sequence Data; Neuropeptides; Peptide Fragments; Protein Conformation; Rats; Receptors, GABA-A; Structure-Activity Relationship | 1990 |
Pharmacological inhibition of forskolin-stimulated adenylate cyclase activity in rat brain by melatonin, its analogs, and diazepam.
Topics: Adenylyl Cyclases; Animals; Benzodiazepinones; Brain; Brain Mapping; Cell Membrane; Colforsin; Corpus Striatum; Diazepam; Dose-Response Relationship, Drug; Enzyme Activation; Flumazenil; In Vitro Techniques; Male; Melatonin; Rats; Rats, Inbred Strains | 1990 |
Diminution by benzodiazepines of the chronotropic responses to noradrenaline in rat isolated atria.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anti-Anxiety Agents; Benzodiazepinones; Clonazepam; Colforsin; Cyclic AMP; Diazepam; Female; Flumazenil; Heart; Heart Rate; In Vitro Techniques; Isoquinolines; Male; Myocardium; Norepinephrine; Rats; Rats, Inbred Strains | 1989 |
Anticonvulsant activity of the diaryltriazine, LY81067: studies using electroencephalographic recording and positron emission tomography.
Topics: Animals; Anticonvulsants; Behavior, Animal; Benzodiazepinones; Brain; Convulsants; Electroencephalography; Epilepsy; Flumazenil; Injections, Intravenous; Male; Papio; Tomography, Emission-Computed; Triazines | 1989 |
The benzodiazepine receptor ligands RO 5-4864 and RO 15-1788 do not block the inhibition of PAF-induced platelet aggregation seen with the hetrazepine WEB2086.
Topics: Adenosine Triphosphate; Animals; Azepines; Benzodiazepinones; Blood Platelets; Female; Flumazenil; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, GABA-A; Triazines; Triazoles | 1989 |
Relaxation of rat vascular muscle by peripheral benzodiazepine modulators.
Topics: Animals; Benzodiazepinones; Calcium; Calcium Channel Blockers; Flumazenil; Guanylate Cyclase; In Vitro Techniques; Isoquinolines; Potassium; Rats; Rats, Inbred WKY; Receptors, GABA-A; Vasodilation | 1989 |
Benzodiazepine interactions with GABAA receptors on chick ciliary ganglion neurons.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Cell Membrane; Cells, Cultured; Chick Embryo; Flumazenil; Flunitrazepam; Ganglia, Parasympathetic; Membrane Potentials; Receptors, GABA-A; Spinal Cord | 1988 |
Regional ontogenetic profile of central and peripheral benzodiazepine receptors in the guinea pig brain.
Topics: Aging; Animals; Benzodiazepinones; Brain; Flumazenil; Guinea Pigs; Receptors, GABA-A | 1988 |
Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: a novel test of anxiety in the rat.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Benzodiazepinones; Buspirone; Carbolines; Convulsants; Exploratory Behavior; Flumazenil; Male; Pyrazoles; Pyridazines; Pyrimidines; Quinolines; Rats | 1986 |
Triazolodiazepines: dissociation of their Paf (platelet activating factor) antagonistic and CNS activity.
Topics: Animals; Anti-Anxiety Agents; Azepines; Benzodiazepinones; Central Nervous System; Flumazenil; Guinea Pigs; Humans; Hypnotics and Sedatives; In Vitro Techniques; Platelet Activating Factor; Platelet Aggregation; Receptors, GABA-A; Tidal Volume; Triazolam | 1987 |
Opposite effects of two ligands for peripheral type benzodiazepine binding sites, PK 11195 and RO5-4864, in a conflict situation in the rat.
Topics: Animals; Benzodiazepinones; Carbolines; Conditioning, Operant; Conflict, Psychological; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Flumazenil; Isoquinolines; Ligands; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
The anxiogenic action of RO 5-4864 in the social interaction test: effect of chlordiazepoxide, RO 15-1788 and CGS 8216.
Topics: Animals; Anxiety; Benzodiazepinones; Chlordiazepoxide; Convulsants; Drug Interactions; Flumazenil; Humans; Male; Motor Activity; Pyrazoles; Rats; Receptors, GABA-A; Social Behavior | 1985 |
Blockade of the diazepam-induced increase in rat striatal acetylcholine content by the specific benzodiazepine antagonists ethyl-beta-carboline-3-carboxylate and Ro 15-1788.
Topics: Acetylcholine; Animals; Benzodiazepines; Benzodiazepinones; Brain Chemistry; Carbolines; Corpus Striatum; Diazepam; Female; Flumazenil; Indoles; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
Clonazepam-induced hyperphagia in nondeprived rats: tests of pharmacological specificity with Ro5-4864, Ro5-3663, Ro15-1788 and CGS 9896.
Topics: Animals; Benzodiazepinones; Clonazepam; Drug Interactions; Feeding Behavior; Flumazenil; Humans; Hyperphagia; Male; Pyrazoles; Rats; Receptors, GABA-A | 1985 |
Monoclonal antibodies to benzodiazepines.
Topics: Animals; Anti-Anxiety Agents; Antibodies, Monoclonal; Benzodiazepines; Benzodiazepinones; Diazepam; Flumazenil; Flunitrazepam; Flurazepam; Mice; Mice, Inbred BALB C; Receptors, GABA-A; Structure-Activity Relationship | 1985 |
Benzodiazepine binding characteristics of embryonic rat brain neurons grown in culture.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Brain; Carbolines; Cells, Cultured; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Flumazenil; gamma-Aminobutyric Acid; Neurons; Pyridazines; Rats; Receptors, GABA-A | 1985 |
Solubilization of peripheral benzodiazepine-binding sites from rat kidney.
Topics: Animals; Benzodiazepinones; Binding, Competitive; Carbolines; Chlordiazepoxide; Clonazepam; Diazepam; Digitonin; Flumazenil; Flurazepam; Guanidine; Guanidines; Hot Temperature; Isoquinolines; Kidney; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Solubility; Time Factors; Urea | 1985 |
Subcellular localization of "peripheral-type" binding sites for benzodiazepines in rat brain.
Topics: Animals; Benzodiazepinones; Binding Sites; Brain; Cell Nucleus; Flumazenil; Male; Mitochondria; Myelin Sheath; Rats; Rats, Inbred Strains; Receptors, GABA-A; Subcellular Fractions; Synaptosomes | 1986 |
Antagonism of flurazepam and other effects of Ro15-1788, PK8165 and Ro5-4864 on the GABA-A receptor complex in rat cuneate nucleus.
Topics: Animals; Anticonvulsants; Benzodiazepinones; Drug Synergism; Flumazenil; Flurazepam; In Vitro Techniques; Male; Medulla Oblongata; Muscimol; Pentobarbital; Picrotoxin; Quinolines; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
Effects of the benzodiazepine receptor ligands midazolam, Ro 15-1788, and Ro 5-4864, alone and in combinations, on platelet serotonin uptake.
Topics: Benzodiazepines; Benzodiazepinones; Blood Platelets; Dose-Response Relationship, Drug; Drug Interactions; Flumazenil; Humans; In Vitro Techniques; Kinetics; Midazolam; Receptors, GABA-A; Serotonin | 1986 |
The peripheral benzodiazepine receptor ligand Ro 5-4864 induces supraspinal convulsions in rabbits. Reversal by the central benzodiazepine antagonist Ro 15-1788.
Topics: Animals; Benzodiazepinones; Convulsants; Electrodes, Implanted; Electroencephalography; Flumazenil; Male; Rabbits; Receptors, GABA-A; Seizures | 1986 |
Convulsant effect of Ro 5-4864, a peripheral type benzodiazepine, on the baboon (Papio papio).
Topics: Animals; Benzodiazepines; Benzodiazepinones; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Isoquinolines; Papio; Receptors, GABA-A; Seizures | 1986 |
Rat hypothalamus contains an antimitogenic factor acting via benzodiazepine receptors.
Topics: Animals; Benzodiazepinones; Flumazenil; Hypothalamus; Ligands; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Mitogens; Peptides; Rats; Receptors, GABA-A; Tissue Extracts | 1986 |
Coexistence of central and peripheral benzodiazepine binding sites in the human pineal gland.
Topics: Aged; Benzodiazepinones; Binding, Competitive; Cell Membrane; Clonazepam; Female; Flumazenil; Flunitrazepam; Humans; Isoquinolines; Male; Middle Aged; Pineal Gland; Receptors, GABA-A | 1987 |
Naloxone-sensitive and GABAA receptor mediated analgesic response of benzodiazepines in mice.
Topics: Analgesics; Animals; Benzodiazepines; Benzodiazepinones; Bicuculline; Female; Flumazenil; Male; Mice; Naloxone; Phenytoin; Reaction Time; Receptors, GABA-A | 1987 |
Enhancement of estradiol-induced DNA synthesis in the anterior pituitary gland by the peripheral-type benzodiazepine receptor ligand Ro 5-4864.
Topics: Animals; Benzodiazepinones; DNA; Drug Synergism; Estradiol; Flumazenil; Male; Mitosis; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Valproic Acid | 1986 |
Diazepam-sensitive specific binding of phenytoin in rat brain.
Topics: Animals; Benzodiazepinones; Binding Sites; Cell Membrane; Cerebral Cortex; Clonazepam; Diazepam; Flumazenil; Male; Phenytoin; Rats; Rats, Inbred Strains | 1986 |
[Effect of RO 15-1788 and RO 5-4684 on the evoked activity of neurons in hippocampal sections].
Topics: Animals; Benzodiazepinones; Evoked Potentials; Flumazenil; Hippocampus; In Vitro Techniques; Rats | 1987 |
Inhibition of cell proliferation of human gliomas by benzodiazepines in vitro.
Topics: Astrocytoma; Benzodiazepines; Benzodiazepinones; Cell Division; Clonazepam; Diazepam; Female; Flumazenil; Glioma; Humans; Male; Middle Aged; Thymidine; Tumor Cells, Cultured | 1988 |
Electrophysiological and pharmacological characterization of peripheral benzodiazepine receptors in a guinea pig heart preparation.
Topics: Action Potentials; Animals; Benzodiazepinones; Clonazepam; Convulsants; Diazepam; Dose-Response Relationship, Drug; Electric Stimulation; Flumazenil; Guinea Pigs; Heart; In Vitro Techniques; Isoquinolines; Myocardial Contraction; Myocardium; Receptors, Cell Surface; Receptors, GABA-A | 1984 |
Autoradiographic localisation of benzodiazepine receptors in the rat pituitary gland.
Topics: Animals; Autoradiography; Benzodiazepinones; Clonazepam; Flumazenil; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Pituitary Gland; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1984 |
Purines interact with 'central' but not 'peripheral' benzodiazepine binding sites.
Topics: Animals; Benzodiazepinones; Binding, Competitive; Brain; Diazepam; Flumazenil; Purines; Rats; Receptors, Cell Surface; Receptors, GABA-A; Synaptosomes | 1982 |
RO5-4864, a ligand for benzodiazepine micromolar and peripheral binding sites: antagonism and enhancement of behavioural effects.
Topics: Animals; Behavior, Animal; Benzodiazepinones; Drug Interactions; Flumazenil; Male; Motor Activity; Phenytoin; Picrotoxin; Pyrazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Benzodiazepines receptor binding in vivo: pharmacokinetic and pharmacological significance.
Topics: Adrenal Glands; Animals; Benzodiazepinones; Brain; Carbolines; Corticosterone; Diazepam; Flumazenil; Flunitrazepam; Kinetics; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
On the convulsant action of Ro 5-4864 and the existence of a micromolar benzodiazepine binding site in rat brain.
Topics: Animals; Benzodiazepinones; Binding Sites; Brain; Convulsants; Diazepam; Electroshock; Flumazenil; Male; Mice; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Seizures | 1984 |
Inhibition of adenosine uptake into rat brain synaptosomes by prostaglandins, benzodiazepines and other centrally active compounds.
Topics: Adenosine; Animals; Benzodiazepines; Benzodiazepinones; Brain; Calmodulin; Carbolines; Flumazenil; Hydroxyzine; Imidazoles; Male; Prostaglandins; Pyrazoles; Rats; Rats, Inbred Strains; Sulfonamides; Synaptosomes | 1983 |
Inhibition of adenosine accumulation by a CNS benzodiazepine antagonist (Ro 15-1788) and a peripheral benzodiazepine receptor ligand (Ro 05-4864).
Topics: Adenosine; Animals; Benzodiazepines; Benzodiazepinones; Central Nervous System; Diazepam; Flumazenil; Flurazepam; Hexobendine; Male; Rats; Synaptosomes; Time Factors | 1983 |
RO5-4864 inhibits the binding of [35S]t-butylbicyclophosphorothionate to rat brain membranes.
Topics: Androstanes; Animals; Azasteroids; Benzodiazepinones; Bicuculline; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Carbolines; Cell Membrane; Cerebellum; Cerebral Cortex; Dose-Response Relationship, Drug; Flumazenil; Hippocampus; Male; Picrotoxin; Radioligand Assay; Rats | 1984 |
Peripheral and central-type benzodiazepine binding sites in mammalian ocular tissues.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Binding Sites; Eye; Female; Flumazenil; Flunitrazepam; Macaca mulatta; Male; Rabbits; Rats; Rats, Inbred Strains | 1984 |
Effects of 4'-chlordiazepam on glycemia and serum lipids in hyperlipidemic rats: interactions with PK 11195 and flumazenil.
Topics: Animals; Benzodiazepinones; Blood Glucose; Dose-Response Relationship, Drug; Drug Interactions; Flumazenil; Hypolipidemic Agents; Isoquinolines; Lipids; Male; Rats; Rats, Wistar; Receptors, GABA-A | 1995 |
Mitochondrial benzodiazepine receptor linked to inner membrane ion channels by nanomolar actions of ligands.
Topics: Animals; Benzodiazepinones; Clonazepam; Convulsants; Flumazenil; Intracellular Membranes; Ion Channels; Isoquinolines; Male; Membrane Potentials; Mitochondria, Heart; Protoporphyrins; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Submitochondrial Particles | 1993 |
Differential effects of 4'-chlorodiazepam on expressed human GABAA receptors.
Topics: Benzodiazepinones; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Clonazepam; Flumazenil; Humans; Quinolines; Receptors, GABA; Transfection | 1995 |
Modification of the photodynamic action of delta-aminolaevulinic acid (ALA) on rat pancreatoma cells by mitochondrial benzodiazepine receptor ligands.
Topics: Aminolevulinic Acid; Animals; Benzodiazepines; Benzodiazepinones; Cell Division; Cell Survival; Clonazepam; Flumazenil; Isoquinolines; Ligands; Mitochondria; Oxygen; Pancreatic Neoplasms; Photochemotherapy; Protoporphyrins; Radiation-Protective Agents; Radiation-Sensitizing Agents; Rats; Receptors, GABA-A; Singlet Oxygen; Tumor Cells, Cultured | 1995 |
Pharmacological relevance of peripheral type benzodiazepine receptors on motor nerve and skeletal muscle.
Topics: Animals; Benzodiazepinones; Diaphragm; Electric Stimulation; Electrophysiology; Female; Flumazenil; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Microelectrodes; Motor Endplate; Motor Neurons; Muscle Contraction; Muscles; Neostigmine; Phrenic Nerve | 1994 |
In vitro inhibition of cellular immune responses by benzodiazepines and PK 11195. Effects on mitogen- and alloantigen-driven lymphocyte proliferation and on IL-1, IL-2 synthesis and IL-2 receptor expression.
Topics: Animals; B-Lymphocytes; Benzodiazepines; Benzodiazepinones; Clonazepam; Diazepam; Female; Flumazenil; Immunity, Cellular; In Vitro Techniques; Interleukin-1; Interleukin-2; Isoquinolines; Lymphocyte Activation; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Neuroimmunomodulation; Receptors, GABA-A; T-Lymphocytes | 1993 |
PK 11195 blockade of benzodiazepine-induced inhibition of forskolin-stimulated adenylate cyclase activity in the striatum.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Benzodiazepines; Benzodiazepinones; Colforsin; Corpus Striatum; Diazepam; Drug Interactions; Flumazenil; GABA-A Receptor Antagonists; Guanosine Triphosphate; Indoles; Isoquinolines; Kinetics; Male; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Virulence Factors, Bordetella | 1996 |
Prevention of ACTH- and adrenalectomy-induced muricidal behavior: by benzodiazepinic ligands.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Aggression; Animals; Benzodiazepinones; Clonazepam; Flumazenil; GABA Modulators; Isoquinolines; Male; Mice; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Time Factors | 1997 |
Modification of cardiac actions of RO 05-4864 by PK 11195 and flumazenil in the perfused rat heart.
Topics: Animals; Benzodiazepinones; Drug Interactions; Female; Flumazenil; Heart; Isoquinolines; Myocardial Contraction; Rats; Rats, Wistar; Regional Blood Flow | 1997 |
Reversal of benzodiazepine inverse agonist FG 7142-induced anxiety syndrome by neurosteroids in mice.
Topics: Animals; Anxiety; Benzodiazepines; Benzodiazepinones; Carbolines; Flumazenil; GABA Antagonists; GABA-A Receptor Antagonists; Isoquinolines; Male; Maze Learning; Mice; Mice, Inbred BALB C; Motor Activity; Progesterone; Receptors, GABA-A; Steroids | 1997 |
[Characteristics of human lymphocyte benzodiazepine receptors].
Topics: Adult; Baclofen; Benzodiazepinones; Binding, Competitive; Diazepam; Flumazenil; GABA Agonists; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Ligands; Lymphocytes; Male; Receptors, GABA-A | 1998 |
Inhibitory regulation of amylase release in rat parotid acinar cells by benzodiazepine receptors.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Amylases; Animals; Atropine; Benzodiazepinones; Carbachol; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Isoproterenol; Male; Muscarinic Agonists; Muscarinic Antagonists; Parotid Gland; Propranolol; Rats; Rats, Wistar; Receptors, GABA-A | 1998 |
Effect of benzodiazepines and neurosteroids on ammonia-induced swelling in cultured astrocytes.
Topics: Ammonia; Astrocytes; Atrial Natriuretic Factor; Benzodiazepines; Benzodiazepinones; Brain Edema; Cell Size; Clonazepam; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Diazepam; Diazepam Binding Inhibitor; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Isoquinolines; Nerve Tissue Proteins; Neuropeptides; Peptide Fragments; Pregnanolone; Pregnenolone; Protoporphyrins; Receptors, GABA-A; Steroids; Up-Regulation | 1998 |
Anti-depressant action of melatonin in chronic forced swimming-induced behavioral despair in mice, role of peripheral benzodiazepine receptor modulation.
Topics: Alprazolam; Analysis of Variance; Animals; Anti-Anxiety Agents; Antioxidants; Benzodiazepinones; Bicuculline; Convulsants; Depression; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Flumazenil; GABA Agents; Immobilization; Isoquinolines; Male; Melatonin; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Receptors, GABA-A; Swimming; Time Factors | 2000 |
2-Arylpyrazolo[1,5-a]pyrimidin-3-yl acetamides. New potent and selective peripheral benzodiazepine receptor ligands.
Topics: Acetamides; Animals; Benzodiazepinones; Binding Sites; Cerebral Cortex; Clonazepam; Flumazenil; Glioma; Intracellular Membranes; Isoquinolines; Kidney; Ligands; Magnetic Resonance Spectroscopy; Molecular Structure; Pyrazoles; Pyrimidines; Rats; Receptors, GABA-A; Structure-Activity Relationship; Thermodynamics; Tumor Cells, Cultured | 2001 |
Binding of [3H]CB 34, a selective ligand for peripheral benzodiazepine receptors, to rat brain membranes.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Female; Flumazenil; Imidazoles; Indoleacetic Acids; Isoquinolines; Ligands; Membrane Proteins; Membranes; Nordazepam; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Tritium | 2001 |
Benzodiazepine receptor-dependent modulation of neutrophil (PMN) free amino- and alpha-keto acid profiles or immune functions.
Topics: Adult; Amino Acids; Benzodiazepinones; Cells, Cultured; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Humans; Hydrogen Peroxide; Isoquinolines; Keto Acids; Male; Midazolam; Naloxone; Neutrophils; Peroxidase; Receptors, GABA-A; Superoxides | 2005 |
Inhibition of Neuropathic Pain by a Single Intraperitoneal Injection of Diazepam in the Rat: Possible Role of Neurosteroids.
Topics: Animals; Benzodiazepinones; Carrier Proteins; Diazepam; Flumazenil; Injections, Intraperitoneal; Interleukin-1beta; Male; Neuralgia; Neurotransmitter Agents; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2016 |