flumazenil has been researched along with ro 16-0154 in 232 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.43) | 18.7374 |
| 1990's | 127 (54.74) | 18.2507 |
| 2000's | 47 (20.26) | 29.6817 |
| 2010's | 49 (21.12) | 24.3611 |
| 2020's | 8 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Buchali, K | 1 |
| Baldwin, RM; de Lanerolle, NC; Hoffer, PB; Johnson, EW; Kim, JH; Mattson, RH; Seibyl, JP; Spencer, DD; Sundaresan, S; Zoghbi, SS | 1 |
| Bicik, I; Haldemann, RC; Hasler, PH; Pfeiffer, A; Schubiger, P; von Schulthess, GK; Wieser, HG | 1 |
| Bartenstein, P; Lehmenkühler, C; Schuierer, G; Sciuk, J | 1 |
| al-Tikriti, MS; Baldwin, RM; Goddard, AW; Laruelle, M; Malison, RT; Seibyl, JP; Sybirska, EH; Woods, SW; Zea-Ponce, Y; Zoghbi, SS | 1 |
| Schubiger, PA | 1 |
| Bartenstein, P; Beer, HF; Lottes, G; Ludolph, A; Scheidhauer, K; Schober, O; Sciuk, J | 1 |
| al-Tikriti, M; Baldwin, R; Charney, D; Innis, R; Johnson, E; Malison, R; Seibyl, J; Woods, S; Zoghbi, S; Zubal, G | 1 |
| al-Tikriti, MS; Baldwin, RM; Innis, RB; Johnson, EW; Laruelle, MA; Malison, RT; Seibyl, JP; Sybirska, EH; Zimmermann, RC; Zoghbi, SS | 1 |
| Beer-Wohlfahrt, H; Bekier, A; Cordes, M; De Roo, M; Deisenhammer, E; Ferstl, F; Hasler, PH; Moser, E; Oettli, R; Schubiger, PA | 1 |
| Barzen, G; Christe, W; Cordes, I; Cordes, M; Eichstädt, H; Ferstl, FJ; Hasler, PH; Henkes, H; Schmitz, B; Schubiger, PA | 1 |
| Dive, D; Franck, G; Maquet, P; van Bentum, AM; van Emde Boas, W; van Huffelen, AC; van Isselt, JW; van Rijk, PP; van Veelen, CW; Velis, DN | 1 |
| Bangerl, I; Beer, HF; Bläuenstein, PA; Bonetti, EP; Delaloye, B; Hasler, PH; Hunkeler, W; Pieri, L; Riccabona, G; Richards, JG | 1 |
| Baldwin, RM; Innis, RB; Johnson, EW; McBride, BJ; Woods, SW; Zoghbi, S | 1 |
| Carmann, H; Dauth, J; Deisenhammer, E; Höll, K; Schubiger, PA | 1 |
| Hisada, K; Kuji, I; Matsuda, H; Mori, H; Shiba, K; Tsuji, S | 1 |
| Hatazawa, J; Kanno, I; Satoh, T; Shimosegawa, E; Uemura, K | 1 |
| Iida, Y; Konishi, J; Magata, Y; Nagata, T; Nishizawa, S; Saji, H; Serikawa, T; Yamamoto, I; Yokoyama, A; Yonekura, Y | 1 |
| Elmqvist, D; Rosén, I; Sjöholm, H | 1 |
| Baldwin, RM; Bremner, JD; Dannals, RF; Dey, HM; Horti, AG; Ng, CK; Ravert, HT; Soufer, R; Stratton, MD; Zea-Ponce, Y | 1 |
| Andersen, JV; Dalgaard, L; Foged, C; Lassen, AN; Paulson, OB; Videbaek, C | 1 |
| Bergström, KA; Kaiser, KP; Koponen, H; Kuikka, JT; Lepola, U; Mittelbach, L; Partanen, K; Pitkänen, A; Vainio, P; Wieler, HJ | 1 |
| Bartenstein, P; Koepp, M | 1 |
| Hokkanen, L; Iivanainen, M; Launes, J; Liewendahl, K; Nikkinen, P; Salonen, O; Sirén, J | 1 |
| Fujita, M; Ikuta, F; Minoshima, S; Miyashita, K; Nakajima, T; Odano, I; Takahashi, N | 1 |
| Busatto, GF; Costa, DC; Ell, PJ; Kerwin, RW; Lingford-Hughes, A; Pilowsky, LS | 1 |
| Kögler, A; Staedt, J; Steinhoff, BJ; Stoppe, G | 1 |
| Fujita, T; Ishizu, K; Konishi, J; Mukai, T; Nishizawa, S; Okazawa, H; Onishi, Y; Shibasaki, H; Tanaka, F; Yonekura, Y | 1 |
| Abi-Dargham, A; Baldwin, RM; Charney, DS; Gandelman, M; Hoffer, PB; Innis, RB; Laruelle, M; Randall, P; Zea-Ponce, Y; Zoghbi, SS | 1 |
| Fujita, T; Ishizu, K; Konishi, J; Nishizawa, S; Okazawa, H; Tanaka, F; Torizuka, K; Yonekura, Y | 1 |
| Benkert, O; Bockisch, A; Hahn, K; Schlegel, S; Schloesser, R; Steinert, H | 1 |
| Baldwin, RM; Gandelman, MS; Innis, RB; Zea-Ponce, Y; Zoghbi, SS | 1 |
| Cordes, M; Felix, R; Hierholzer, J; Meencke, H; Richter, W; Schmitz, B; Schröder, R; Straub, HB; Venz, S | 1 |
| Fukushima, T; Hisada, K; Jibiki, I; Kurokawa, K; Matsuda, H; Tsuji, S; Yamaguchi, N | 2 |
| Baldwin, RM; Charney, DS; Dey, HM; Olson, C; Seibyl, JP; Smith, EO; Stubbs, JB; Zea-Ponce, Y; Zoghbi, SS; Zubal, IG | 1 |
| Cordes, M; Eichstädt, H; Felix, R; Hierholzer, J; Keske, U; Richter, W; Schmitz, B; Siekmann, R; Venz, S | 1 |
| al-Tikriti, MS; Baldwin, RM; Charney, DS; Frost, JJ; Hoffer, PB; Laruelle, M; Price, JC; Rattner, Z; Zea-Ponce, Y; Zoghbi, SS | 1 |
| Abi-Dargham, A; al-Tikriti, MS; Baldwin, RM; Charney, DS; Hoffer, PB; Innis, RB; Laruelle, M; Zea-Ponce, Y; Zoghbi, SS | 1 |
| al-Tikriti, MS; Baldwin, RM; Dey, HM; Innis, RB; Zea-Ponce, Y; Zoghbi, SS | 1 |
| Hagspiel, KD; Hermes, M; Kujat, C; Neidl, KF; Voges, M | 1 |
| Andersen, JV; Dalgaard, L; Foged, C; Friberg, L; Holm, S; Lassen, NA; Videbaek, C; Wammen, S | 1 |
| Baldwin, RM; Innis, RB; Zea-Ponce, Y; Zoghbi, SS | 1 |
| Abi-Dargham, A; Baldwin, RM; Bremner, JD; Charney, DS; Hyde, TM; Laruelle, M; Rattner, Z; Seibyl, J; Zea-Ponce, Y; Zoghbi, SS | 1 |
| Brodie, MJ; Duncan, S; Gillen, GJ | 1 |
| Busemann Sokole, E; Hengst, D; Stubbs, JB; van Royen, EA; Verhoeff, NP | 1 |
| Abi-Dargham, A; al-Tikriti, MS; Charney, DS; Frost, JJ; Hoffer, PB; Laruelle, M; Price, J; Rattner, Z; Zea-Ponce, Y; Zoghbi, SS | 1 |
| Hisada, K; Kuji, I; Matsuda, H; Tsuji, S | 1 |
| al-Tikriti, MS; Baldwin, RM; Bradberry, C; Bremner, JD; During, M; Malison, RT; Seibyl, JP; Sybirska, E; Zea-Ponce, Y; Zoghbi, S | 1 |
| Blok, H; Busemann Sokole, E; Erbas, B; Kapucu, O; Van Royen, EA; Verhoeff, NP | 1 |
| Fujita, M; Furusawa, T; Hayashi, S; Miyashita, K; Nakajima, T; Naritomi, H; Odano, I; Sakai, K; Takahashi, N | 1 |
| Fujita, H; Hatazawa, J; Inugami, A; Kanno, I; Miura, S; Noguchi, K; Ogawa, T; Okudera, T; Satoh, T; Shimosegawa, E | 1 |
| Fujita, T; Ishizu, K; Konishi, J; Magata, Y; Mukai, T; Nishizawa, S; Pagani, M; Shibasaki, H; Tamaki, N; Yonekura, Y | 1 |
| Ida, K; Kurami, M; Matsumoto, H; Torizuka, K; Yanai, A; Yonekura, Y; Yoshimura, H | 1 |
| Lassen, NA | 1 |
| Buck, A; Burger, C; Leenders, KL; Schubiger, AP; von Schulthess, GK; Westera, G | 1 |
| Diehl, B; Kuwert, T; Puskás, C; Puskaś, Z; Schober, O; Schuierer, G; Stodieck, SR; Vollet, B | 1 |
| Fukuyama, H; Matsuda, H; Matsuda, K; Morimoto, K; Nakagawara, J; Nishimura, T; Sakai, F; Shinohara, Y; Torizuka, K; Toru, M; Uemura, K; Yonekura, Y | 4 |
| Fukuda, H; Goto, R; Ito, H; Kawashima, R; Koyama, M; Ono, S; Sato, K | 2 |
| Fujita, T; Ishizu, K; Konishi, J; Mukai, T; Nishizawa, S; Okazawa, H; Onishi, Y; Tanaka, F; Yonekura, Y | 3 |
| Fukuchi, M; Kawabata, K; Sugita, M; Tachibana, H | 1 |
| Buck, A; Burger, C; vonSchulthess, GK; Westera, G | 1 |
| Buck, A; Burger, C | 1 |
| Anezaki, T; Inuzuka, T; Odano, I; Ohkubo, M; Onishi, Y; Takahashi, M; Tsuji, S; Yonekura, Y | 1 |
| Fukuyama, H; Matsuda, K; Morimoto, K; Nakagawara, J; Tohru, M; Torizuka, K; Uemura, K; Yonekura, Y | 1 |
| Fukuyama, H; Matsuda, K; Morimoto, K; Nakagawara, J; Thoru, M; Torizuka, K; Uemura, K; Yonekura, Y | 1 |
| Fujita, M; Fukuchi, K; Hashikawa, K; Ishida, M; Matsumoto, M; Moriwaki, H; Nishimura, T; Oku, N; Seike, Y; Terakawa, H; Uehara, T; Watanabe, Y | 1 |
| Discepolo, A; Grivet-Fojaja, MR; Lassen, NA; Mainenti, PP; Postiglione, A; Salvatore, M; Soricelli, A; Varrone, A | 1 |
| Kitamura, S; Komaba, Y; Komiyama, T; Koshi, Y; Mishina, M; Ohyama, M; Sakayori, O; Terashi, A; Tsuganesawa, T | 1 |
| Hayashida, K; Hirose, Y; Ishida, Y; Miyake, Y; Miyashita, K; Nishimura, T; Tanaka, Y | 1 |
| Kaneko, K; Kuramaji, A; Nabeshima, T; Shibuya, H; Toru, M | 1 |
| Busatto, GF; Costa, DC; David, AS; Ell, PJ; Kerwin, RW; Lucey, JV; Pilowsky, LS | 1 |
| Lassen, NA; Nakagawara, J; Sperling, B | 1 |
| Kawabata, K; Tachibana, H | 1 |
| Fujita, M; Hashikawa, K; Kodaka, R; Nagai, T; Nishimura, T; Uehara, T | 1 |
| Fukumitsu, N; Kawakami, K; Mori, Y; Sue, H; Uchiyama, M | 2 |
| Hattori, N; Ikeda, A; Ishizu, K; Konishi, J; Mikuni, N; Nishizawa, S; Okazawa, H; Onishi, Y; Shibasaki, H; Tanaka, F; Terada, K; Yonekura, Y | 1 |
| Brekelmans, GJ; Debets, RM; Franck, G; Meiners, LC; Sadzot, B; van Huffelen, AO; van Isselt, JW; van Veelen, CW | 1 |
| Fujita, M; Fukuchi, K; Hashikawa, K; Ishida, M; Kusuoka, H; Moriwaki, H; Nishimura, T; Oku, N; Seike, Y; Tanabe, H; Uehara, T | 1 |
| Lassen, NA; Postiglione, A; Salvatore, M | 1 |
| Bubeck, B; Demisch, S; Sauer, H; Schröder, J | 1 |
| Fukunaga, M; Itaya, M; Kitayama, A; Mimura, H; Morita, K; Muranaka, A; Nagai, K; Ono, S; Otsuka, N; Sone, T; Tomomitsu, T; Yanagimoto, S | 1 |
| Iga, T; Ito, K; Katashima, M; Kojima, Y; Kotaki, H; Momose, T; Sasaki, Y; Sawada, Y; Yamamoto, K | 1 |
| Hamano, H; Ohnuki, Y; Ohta, T; Shinohara, Y; Takahashi, W; Yamamoto, M | 1 |
| Dong, Y; Fukuyama, H; Nabatame, H; Shibasaki, H; Yamauchi, H; Yonekura, Y | 1 |
| Fujita, S; Odano, I; Ohkubo, M; Takahashi, M | 1 |
| Verhoeff, NP | 1 |
| Fukumura, T; Ichiya, Y; Kuwabara, Y; Masuda, K; Sasaki, M; Yoshida, T | 1 |
| Bergman, J; Haaparanta, M; Härkönen, R; Jääskeläinen, S; Kälviäinen, R; Knuuti, J; Lamusuo, S; Mervaala, E; Nousiainen, U; Rinne, JK; Rinne, JO; Ruotsalainen, U; Ruottinen, HM; Solin, O; Vapalahti, M; Ylinen, A | 1 |
| Nakabeppu, Y; Nakajo, M; Naruo, T; Nozoe, S; Obo, Y; Takigawa, M; Tanaka, H; Tani, A; Tsuchimochi, S | 1 |
| Ball, S; Busatto, GF; Costa, DC; David, AS; Ell, PJ; Hemsley, DR; Jones, SH; Kerwin, RW; Pilowsky, LS | 1 |
| Cordes, M; Eichstädt, H; Felix, R; Hierholzer, J; Keske, U; Meencke, HJ; Straub, HB; Venz, S | 1 |
| Ishibashi, M; Kato, H; Kimura, A; Matsuishi, T; Onishi, Y; Yamashita, Y; Yonekura, Y | 1 |
| Prohovnik, I | 1 |
| Amano, T; Fukuuchi, Y; Hashimoto, J; Itoh, Y; Kubo, A; Nakamura, K; Sasaki, T | 1 |
| Fukuchi, K; Hashikawa, K; Hori, M; Ishida, M; Matsumoto, M; Moriwaki, H; Nishimura, T; Oku, N; Seike, Y | 1 |
| Abe, T; Hayabuchi, N; Ishibashi, M; Matsuishi, T; Ohnishi, Y; Sakai, T; Yamashita, Y; Yonekura, Y | 1 |
| Ichikawa, A; Kuji, I; Sumiya, H; Tonami, N; Tsuji, S | 1 |
| Hatazawa, J; Shimosegawa, E | 1 |
| Abi-Dargham, A; Anjilvel, S; Baldwin, RM; Charney, DS; Ellis, S; Innis, RB; Krystal, JH; Laruelle, M; Petrakis, IL; Rajeevan, N; Scanley, BE; Seibyl, JP; Zoghbi, S | 1 |
| Ichise, M; Koga, S; Matsumura, K; Nakashima, H; Takeda, K; Takeuchi, A; Toyama, H; Yoshida, T | 1 |
| Amano, T; Fukuuchi, Y; Hashimoto, J; Itoh, Y; Kubo, A; Shimizu, T | 1 |
| Maruoka, S; Sato, S; Shirane, R; Yoshimoto, T | 1 |
| Abi-Dargham, A; Baldwin, RM; Charney, DS; Fujita, M; Innis, RB; Jatlow, PA; Krystal, JH; Rajeevan, N; Seibyl, JP; Soares, JC; Verhoeff, NP; Woods, SW; Zoghbi, SS | 1 |
| Abi-Dargham, A; Baldwin, RM; Charney, D; D'Souza, C; de Erasquin, G; Innis, RB; Krystal, J; Laruelle, M; Mawlawi, O; Seibyl, J; Zoghbi, S | 1 |
| Cooper, MR | 1 |
| Morimoto, K | 1 |
| Hosoi, R; Inoue, O; Kobayashi, K; Watanabe, Y | 1 |
| Cho, IH; Fukuchi, K; Hasegawa, Y; Hayashida, K; Kume, N; Nishimura, T | 1 |
| Knudsen, GM; Ott, P; Paulson, OB; Videbaek, C | 1 |
| Postiglione, A; Salvatore, M; Soricelli, A; Varrone, A | 1 |
| Bogerts, B; Czcervenka, C; Danos, P; Krause, R; Kropf, D; Northoff, G; Otto, H; Steinke, R; Ulrich, S | 1 |
| Ishiwata, A; Katayama, Y; Kitamura, S; Komaba, Y; Komiyama, T; Koshi, Y; Mishina, M; Ohyama, M; Sakayori, O; Terashi, A | 1 |
| Gotoh, S; Kamiyama, H; Kobayashi, N; Makino, K; Takamura, H | 1 |
| Ishii, Y; Sadato, N; Takahashi, N; Tsuchida, T; Yamamoto, K; Yonekura, Y | 1 |
| Cluckie, A; Curran, HV; Fleminger, S; Kapczinski, F; Lader, M; Quevedo, J; Toone, B | 1 |
| Baldwin, R; Bremner, JD; Charney, DS; Horti, A; Innis, RB; Ng, CK; Seibyl, JP; Soufer, R; Staib, LH; Tan, PZ; Zea-Ponce, Y; Zoghbi, S | 1 |
| Fujita, M; Hyder, F; Innis, RB; Mattson, RH; Petroff, OA; Rajeevan, N; Rothman, DL; Seibyl, JP; Verhoeff, NP; Zoghbi, SS | 1 |
| Baldwin, R; Bremner, JD; Charney, DS; Horti, A; Soufer, R; Staib, LH; Zea-Ponce, Y | 1 |
| Ishii, K; Ishiwata, K; Katayama, Y; Kitamura, S; Mishina, M; Oda, K; Ohyama, M; Senda, M; Toyama, H | 1 |
| Abi-Dargham, A; Charney, DS; D'Souza, CD; Degen, K; Fujita, M; Gil, R; Innis, RB; Krystal, JH; Rajeevan, N; Seibyl, JP; Soares, JC; van Dyck, CH; Verhoeff, NP; Zoghbi, SS | 1 |
| Abe, Y; Kaneta, T; Maruoka, S; Takahashi, S; Yamada, S; Yamazaki, T | 1 |
| Baldwin, R; Bremner, JD; Cappiello, A; Charney, DS; Fujita, M; Goddard, AW; Innis, RB; Silbersweig, D; Staib, L; Stern, E; White, T; Woods, S | 1 |
| Iida, Y; Kitano, H; Konishi, J; Magata, Y; Nishizawa, S; Saji, H; Shiozaki, T | 1 |
| Kusuoka, H; Nakamura, H; Nakano, T; Nishimura, H; Nishimura, T; Watanabe, Y; Yutani, K | 1 |
| Bremner, JD; Charney, DS; Innis, RB; Southwick, SM; Staib, L; Zoghbi, S | 1 |
| Acton, PD; Boddington, SJ; Costa, DC; Ell, PJ; Gacinovic, S; Kerwin, RW; Lingford-Hughes, AR; Marshall, EJ; Pilowsky, LS | 1 |
| Arigoni, M; Bouras, C; Broggini, C; Buck, A; Graf, C; Ibáñez, V; Millet, P; Slosman, D; Walder, B; Westera, G | 1 |
| Hasselbalch, SG; Knudsen, GM; Paulson, OB; Pinborg, LH; Sørensen, SA; Videbaek, C; Wagner, A | 1 |
| Gee, A; Hosoi, R; Inoue, O; Itoh, T; Kobayashi, K; Suzuki, K | 1 |
| Diehl, B; Kellinghaus, C; Kuwert, T; Lüdemann, P; Matheja, P; Ringelstein, EB; Schober, O; Schuierer, G; Weckesser, M; Weitemeyer, L | 1 |
| Föhr, J; Husso-Saastamoinen, M; Könönen, M; Kuikka, JT; Lehtonen, J; Mervaala, E; Partanen, J; Tammi, AK; Tiihonen, J; Valkonen-Korhonen, M; Viinamäki, H | 1 |
| Borbély, K | 1 |
| Fukumitsu, N; Mori, Y; Ogi, S; Tsuchida, D; Uchiyama, M | 1 |
| Brooks, DJ; Cunningham, VJ; Feeney, A; Hirani, E; Hume, SP; Lingford-Hughes, A; Nutt, DJ; Osman, S; Pike, VW | 1 |
| Aihara, M; Matsuda, K; Mihara, T; Sata, Y; Yagi, K; Yonekura, Y | 1 |
| Buck, A; Graf, C; Ibáñez, V; Millet, P; Walder, B | 1 |
| Clausen, M; Klutmann, S; Müller, V; Röther, J; Saur, D; Weiller, C | 1 |
| Boon, P; Dierckx, R; Goethals, I; Van de Wiele, C | 1 |
| Hikosaka, K; Kaji, T; Kuge, Y; Nishijima, KC; Ohkura, K; Seki, K; Tamaki, N; Tsukamoto, E; Ueno, S | 1 |
| Inoue, H; Kaji, T; Kuge, Y; Minematsu, K; Shiga, T; Tagaya, M; Tamaki, N; Yokota, C | 1 |
| Anand, A; Baldwin, RM; Bozkurt, A; Charney, DS; Degen, K; Fujita, M; Innis, RB; Khan, SA; Kugaya, A; Mason, GF; Sanacora, G; Seibyl, JP; Seneca, NM; Verhoeff, NP; Zoghbi, SS | 1 |
| Fisch, HU; Kosel, M; Luginbühl, M; Rudolph, U; Schlaepfer, TE; Schmitt, W; Wielepp, P | 1 |
| Daftary, A; Goldstein, B; Seibyl, JP; Shulman, A; Strashun, AM | 1 |
| Fukumitsu, N; Mori, Y; Ogi, S; Uchiyama, M | 3 |
| Baldwin, RM; Bozkurt, A; Denucci, CC; Dillon, MS; Fujita, M; Innis, RB; Kugaya, A; Seibyl, JP; Southwick, SM; Verhoeff, NP; Zoghbi, SS | 1 |
| Daftary, A; Gottschalk, C; Seibyl, JP; Shulman, A; Strashun, AM; Zoghbi, SS | 1 |
| Aburano, T; Hashizume, K; Kiriyama, K; Nakai, H; Okizaki, A; Shuke, N; Tanaka, T; Yamamoto, W; Zhao, C | 1 |
| Fukuchi, K; Hashikawa, K; Hori, M; Matsumoto, M; Moriwaki, H; Nishimura, T; Oku, N; Seike, Y; Watanabe, Y; Yamamoto, H | 1 |
| Matsuda, K; Morimoto, K; Tamagami, H | 1 |
| Baldwin, R; Frohlich, E; Gottschalk, C; Gueorguieva, R; Innis, RB; Jatlow, P; Krystal, JH; O'Malley, S; Perry, E; Petrakis, IL; Ruff, E; Seibyl, JP; Staley, JK; van Dyck, CH; Verhoeff, NP; Weinzimmer, D | 1 |
| Boutros, NN; Cooper, T; D'Souza, DC; Donahue, L; Ebersole, JS; Gil, RB; Krystal, JH; MacDougall, LM; Seibyl, J; Zuzarte, E | 1 |
| Graf, C; Ibáñez, V; Millet, P; Moulin, M | 1 |
| Hashizume, K; Hodozuka, A; Tanaka, T; Tsuda, H | 1 |
| Ikeda, S; Kawawaki, H; Kuki, I; Okazaki, S; Tomiwa, K | 1 |
| Abe, K; Honda, H; Kaneko, K; Koga, H; Mihara, F; Morioka, T; Ohya, N; Sasaki, M; Sawamoto, H; Yoshiura, T | 1 |
| Buchert, R; Knab, R; Röther, J; Saur, D; Weiller, C | 1 |
| Baba, K; Fujiwara, T; Inoue, Y; Matsuda, K; Mihara, T; Nakamura, F; Terada, K; Tottori, T; Umeoka, S; Usui, K; Usui, N | 1 |
| Hirashima, Y; Morimoto, M; Nishimura, A; Osamura, T; Sugimoto, T | 1 |
| Ikeda, H; Kawawaki, H; Kuki, I; Oba, S; Okazaki, S; Tomiwa, K | 1 |
| Hatazawa, J; Kato, A; Kato, H; Kishima, H; Kitagawa, K; Oku, N; Saitoh, Y; Shimosegawa, E; Yoshimine, T | 1 |
| Amemiya, S; Hamamoto, M; Katayama, Y; Kumagai, T; Mishina, M; Nishiyama, Y; Ueda, M | 1 |
| Bogerts, B; Grosser, O; Heinzel, A; Northoff, G; Otto, H; Poeppel, TD; Steinke, R | 1 |
| Chida, K; Kobayashi, M; Ogasawara, K; Ogawa, A; Otawara, Y; Saito, H; Suga, Y; Yoshida, K | 1 |
| Atack, JR; Burns, HD; Dawson, GR; Eng, WS; Francis, B; Gibson, RE; Hargreaves, RJ; Ryan, C; Sohal, B | 1 |
| Batis, JC; Bois, F; Cosgrove, KP; Esterlis, I; Kloczynski, TA; Krishnan-Sarin, S; Makuch, R; O'Malley, S; Perry, E; Seibyl, JP; Staley, JK; Stiklus, SM; Tamagnan, GD | 1 |
| Aso, K; Chida, K; Kobayashi, M; Kuroda, H; Ogasawara, K; Ogawa, A; Yoshida, K | 1 |
| Aso, K; Beppu, T; Chida, K; Kobayashi, M; Kuroda, H; Ogasawara, K; Ogawa, A | 1 |
| Aso, K; Chida, K; Kobayashi, M; Ogasawara, K; Ogawa, A; Suga, Y; Terasaki, K; Tsushina, E; Yoshida, K | 1 |
| Baba, K; Inoue, Y; Matsuda, K; Matsuhashi, M; Nakamura, F; Nikaido, K; Terada, K; Tottori, T; Umeoka, S; Usui, K; Usui, N | 1 |
| Comerci, M; De Falco, C; Iavarone, A; Loré, E; Milan, G; Panico, MR; Pappatà, S; Postiglione, A; Quarantelli, M; Salvatore, M; Sansone, V; Varrone, A; Vicidomini, C | 1 |
| Cauli, A; Marrosu, F; Mathieu, A; Piga, M; Porru, G; Sanna, G; Serra, A; Vacca, A | 1 |
| Ishikawa, N; Kobayashi, M; Kobayashi, Y | 1 |
| Fujisawa, H; Iwanaga, H; Koizumi, H; Kurokawa, T; Nakagawara, J; Suehiro, E; Suzuki, M | 1 |
| Heiss, WD | 1 |
| Ahn, K; D'Souza, DC; Gil, R; Seibyl, J; Sewell, RA | 1 |
| Aso, K; Chida, K; Fujiwara, S; Kobayashi, M; Kuroda, H; Ogasawara, K; Ogawa, A; Terasaki, K; Yoshida, K | 1 |
| Aso, K; Chida, K; Kobayashi, M; Kuroda, H; Ogasawara, K; Ogawa, A; Saito, H; Yoshida, K | 1 |
| Hamano, S; Higurashi, N; Ida, H; Minamitani, M; Oritsu, T; Sasaki, M | 1 |
| Fujii, E; Harada, M; Kagami, S; Miyazaki, M; Mori, K; Mori, T; Toda, Y | 2 |
| Aso, K; Chida, K; Fujiwara, S; Kobayashi, M; Kuroda, H; Ogasawara, K; Ogawa, A; Suzuki, T; Terasaki, K; Yoshida, K | 1 |
| Fujii, E; Harada, M; Hashimoto, T; Kagami, S; Miyazaki, M; Mori, K; Mori, T; Toda, Y | 1 |
| Chida, K; Kobayashi, M; Kubo, Y; Kuroda, H; Ogasawara, K; Ogawa, A; Suzuki, T; Yamashita, T; Yoshida, K | 1 |
| Aso, K; Chida, K; Fujiwara, S; Kobayashi, M; Kubo, Y; Kuroda, H; Ogasawara, K; Ogawa, A; Suzuki, T; Terasaki, K; Yoshida, K | 1 |
| Amou, K; Inoue, T; Kawawaki, H; Kuki, I; Nukui, M; Okazaki, S; Shiomi, M; Togawa, M; Tomiwa, K | 1 |
| Bois, F; Cosgrove, KP; Esterlis, I; Kirk, K; Krishnan-Sarin, S; Lee, D; McKee, SA; O'Malley, SS; Seibyl, JP; Staley, JK; Stiklus, SM | 1 |
| Hatazawa, J; Isohashi, K; Kato, H; Kazui, H; Kimura, N; Shimosegawa, E | 1 |
| Houkin, K; Kawabori, M; Kurisu, K; Kuroda, S; Mabuchi, S; Nakayama, N; Niiya, Y; Ohta, Y | 1 |
| Baba, K; Hatazawa, J; Imaizumi, M; Isohashi, K; Kato, H; Matsuda, K; Shimosegawa, E | 1 |
| Fumoto, K; Honjo, K; Kamiyama, K; Murahashi, T; Nakagawara, J; Nakamura, H; Osato, T; Sugio, H; Takada, H; Watanabe, T | 1 |
| Hatazawa, J; Hirata, M; Hosomi, K; Kato, A; Khoo, HM; Kishima, H; Maruo, T; Oshino, S; Shimosegawa, E; Tani, N; Yoshimine, T | 1 |
| Hanyu, H; Hirao, K; Iwamoto, T; Kanetaka, H; Kume, K; Sakurai, H; Sato, T | 1 |
| Fujisawa, H; Iwanaga, H; Koizumi, H; Nakagawara, J; Suehiro, E; Suzuki, M | 1 |
| Kamiyama, K; Nakagawara, J; Nakamura, H; Takahashi, M | 1 |
| Endo, K; Shibata, Y | 1 |
| Baba, K; Fujitani, S; Inoue, Y; Kajita, Y; Matsuda, K; Mihara, T; Nakamura, F; Terada, K; Tottori, T; Usui, K; Usui, N; Wakabayashi, T | 1 |
| Houkin, K; Kubo, N; Kuge, Y; Kuroda, S; Magota, K; Saito, H; Shichinohe, H; Tamaki, N; Zhao, S | 1 |
| Noguchi, K; Taguchi, Y; Takashima, S; Tanaka, K | 1 |
| Charnay, Y; Dumas, N; Ghezzi, C; Ginovart, N; Millet, P; Moulin-Sallanon, M; Tournier, BB; Tsartsalis, S | 1 |
| Ideguchi, M; Ishihara, H; Iwanaga, H; Koizumi, H; Nomura, S; Oka, F; Sadahiro, H; Shirao, S; Suehiro, E; Suzuki, M; Yoneda, H | 1 |
| Bois, F; Carson, RE; Cosgrove, KP; Esterlis, I; Glahn, DC; Kloczynski, T; Krystal, JH; Lancaster, J; McKay, R; O'Malley, S; Perkins, E; Pittman, B | 1 |
| Bois, F; Cahill, J; Carbuto, M; Cortes-Briones, J; D'Souza, DC; Gunduz-Bruce, H; Pittman, B; Radhakrishnan, R; Ranganathan, M; Schnakenberg, A; Sewell, RA; Skosnik, PD | 1 |
| Ahn, KH; D'Souza, DC; Elander, J; Gunduz-Bruce, H; Krystal, J; Pittman, B; Ranganathan, M; Sewell, A | 1 |
| Fukuoka, M; Hattori, Y; Hirose, S; Horino, A; Inoue, T; Kawawaki, H; Kuki, I; Nukui, M; Okazaki, S; Tomiwa, K; Tsuji, H | 1 |
| Kiya, H; Koizumi, H; Nomura, S; Suehiro, E; Suzuki, M | 1 |
| Aida, I; Higuchi, S; Nakada, T; Nakajima, T; Suzuki, Y | 1 |
| Hatazawa, J; Isohashi, K; Kato, H; Shimosegawa, E | 1 |
| Fujiwara, S; Kobayashi, M; Kojima, D; Komoribayashi, N; Kubo, Y; Ogasawara, K; Oikawa, K; Omama, S; Terasaki, K | 1 |
| Hamano, SI; Hirata, Y; Ikemoto, S; Kikuchi, K; Matsuura, R | 1 |
| Baba, S; Enoki, H; Fujimoto, A; Itamura, S; Kanai, S; Masui, T; Nishimura, M; Okanishi, T; Sato, K | 1 |
| Fujita, KI; Fukuchi, K; Hokama, T; Kawai, K; Kobayashi, M; Mizutani, A; Nishi, K; Nishii, R; Shikano, N; Takahashi, K; Takasu, H | 1 |
| Ginovart, N; Graf, CE; Ibáñez, V; Millet, P; Tournier, BB; Tsartsalis, S | 1 |
| Kojima, D; Komoribayashi, N; Ogasawara, K; Ohmama, S; Oikawa, K; Shimada, Y; Yoshida, J | 1 |
| Ahmed, T; Arndt, MB; Gazi, MA; Haque, MA; Haque, NMS; Haque, R; Hasan, MM; Hossain, M; Mahfuz, M; Mondal, D; Nahar, B; Naila, NN; Walson, JL | 1 |
| Hashimoto, K; Horiuchi, R; Kanemaru, K; Kinouchi, H; Murayama, H; Yagi, T; Yoshioka, H | 1 |
| Hashimoto, K; Kanemaru, K; Kinouchi, H; Senbokuya, N; Yagi, T; Yamasaki, M; Yoshioka, H | 1 |
| Koji, T; Kubo, Y; Matsumoto, Y; Murakami, T; Ogasawara, K; Yoshida, K | 1 |
| Chida, K; Fujiwara, S; Kobayashi, M; Kubo, Y; Miyoshi, K; Ogasawara, K; Sato, S; Terasaki, K; Yoshida, K | 1 |
| Ando, Y; Funayama, N; Kawai, K; Minezumi, T; Sawada, M; Sehara, Y | 1 |
| Acar, N; Ajana, S; Berdeaux, O; Bretillon, L; Bron, AM; Buaud, B; Creuzot-Garcher, CP; Delcourt, C; Grégoire, S; He, Z; Hejblum, BP; Jacqmin-Gadda, H; Korobelnik, JF; Martine, L; Merle, BMJ | 1 |
| Akamatsu, Y; Chida, K; Dobashi, K; Fujiwara, S; Katakura, Y; Kimura, K; Kobayashi, M; Kubo, Y; Ogasawara, K; Terasaki, K; Yasuda, S; Yoshida, K | 1 |
| Hattori, T; Horino, A; Inoue, T; Kawawaki, H; Kuki, I; Nagase, S; Nukui, M; Okazaki, S; Sakuma, H; Yamada, N; Yamamoto, N | 1 |
9 review(s) available for flumazenil and ro 16-0154
| Article | Year |
|---|---|
[New receptor ligands for single-photon emission tomography of the brain].
Topics: Brain; Brain Mapping; Flumazenil; Humans; Radioligand Assay; Receptors, Cholinergic; Receptors, GABA-A; Receptors, Opioid; Receptors, Serotonin; Tomography, Emission-Computed, Single-Photon | 1992 |
[Benzodiazepine receptor imaging with positron emission tomography and single photon emission tomography].
Topics: Brain; Brain Damage, Chronic; Brain Mapping; Cerebral Cortex; Epilepsies, Partial; Epilepsy, Temporal Lobe; Flumazenil; Humans; Image Processing, Computer-Assisted; Iodine Radioisotopes; Receptors, GABA-A; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1995 |
[Single photon emission tomography (SPECT). Cerebral function diagnosis for the clinical routine. Indications and radiotracers].
Topics: Benzamides; Brain Diseases; Flumazenil; Humans; Iodine Radioisotopes; Organotechnetium Compounds; Oximes; Pyrrolidines; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon | 1993 |
[Evaluation of benzodiazepine receptor in the cerebral cortex of Parkinson's disease using 123I-iomazenil SPECT].
Topics: Amphetamines; Animals; Cerebral Cortex; Flumazenil; Humans; Iodine Radioisotopes; Iofetamine; Parkinson Disease; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1997 |
Imaging neurochemistry of cerebrovascular disease with PET and SPECT.
Topics: Brain; Carbon Radioisotopes; Cerebrovascular Disorders; Flumazenil; Humans; Receptors, GABA-A; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1998 |
[Benzodiazepine receptor imaging in the brain: recent developments and clinical validity].
Topics: Brain; Carbon Radioisotopes; Epilepsy, Temporal Lobe; Flumazenil; Humans; Iodine Radioisotopes; Panic Disorder; Radiopharmaceuticals; Receptors, GABA-A; Reproducibility of Results; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1999 |
[Functional imaging (PET and SPECT) in epilepsy].
Topics: Animals; Brain; Cerebrovascular Circulation; Epilepsy; Flumazenil; Fluorodeoxyglucose F18; GABA Modulators; Humans; Iodine Radioisotopes; Radiopharmaceuticals; Receptors, Cholinergic; Receptors, GABA; Receptors, GABA-A; Receptors, Histamine H1; Receptors, Opioid; Seizures; Sensitivity and Specificity; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 2001 |
Is central benzodiazepine receptor imaging useful for the identification of epileptogenic foci in localization-related epilepsies?
Topics: Brain; Epilepsies, Partial; Flumazenil; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Iodine Radioisotopes; Radiopharmaceuticals; Receptors, GABA-A; Temporal Lobe; Tomography, Emission-Computed | 2003 |
[Usefulness of 123I-iomazenil SPECT in pediatric patients with neurological disease].
Topics: Brain; Epilepsy; Flumazenil; Humans; Iodine Radioisotopes; Nervous System Diseases; Radiopharmaceuticals; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 2012 |
32 trial(s) available for flumazenil and ro 16-0154
| Article | Year |
|---|---|
Evaluation of a multicentre study with Iomazenil--a benzodiazepine receptor ligand.
Topics: Adult; Alzheimer Disease; Brain Chemistry; Epilepsies, Partial; Evaluation Studies as Topic; Female; Flumazenil; Humans; Iodine Radioisotopes; Male; Middle Aged; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1991 |
123-I-iomazenil-SPECT in patients with focal epilepsies--a comparative study with 99mTc-HMPAO-SPECT, CT and MR.
Topics: Adult; Epilepsies, Partial; Female; Flumazenil; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; Male; Middle Aged; Organotechnetium Compounds; Oximes; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed | 1991 |
Synthesis and PET imaging of the benzodiazepine receptor tracer [N-methyl-11C]iomazenil.
Topics: Adult; Animals; Carbon Radioisotopes; Female; Flumazenil; Humans; Iodine Radioisotopes; Isotope Labeling; Ligands; Male; Papio; Receptors, GABA-A; Spectrophotometry, Ultraviolet; Tissue Distribution; Tomography, Emission-Computed; Whole-Body Counting | 1995 |
[Phase 1 clinical study of 123I-iomazenil: a new probe to evaluate central-type benzodiazepine receptor with SPECT].
Topics: Adult; Brain; Flumazenil; Humans; Iodine Radioisotopes; Male; Middle Aged; Receptors, GABA-A; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 1995 |
[Preoperative evaluation of drug resistant focal epilepsies with 123I-iomazenil SPECT. Comparison with vidio/EEG monitoring and postoperative results].
Topics: Adolescent; Adult; Brain; Child; Electroencephalography; Epilepsies, Partial; Female; Flumazenil; Follow-Up Studies; Humans; Iodine Radioisotopes; Male; Middle Aged; Monitoring, Physiologic; Organotechnetium Compounds; Oximes; Postoperative Period; Predictive Value of Tests; Technetium Tc 99m Exametazime; Time Factors; Tomography, Emission-Computed, Single-Photon; Video Recording | 1994 |
Lack of effect of concomitant clobazam on interictal 123I-iomazenil SPECT.
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Brain; Clobazam; Epilepsy; Female; Flumazenil; Humans; Iodine Radioisotopes; Male; Tomography, Emission-Computed, Single-Photon | 1993 |
[A phase 3 clinical trial of 123I-iomazenil, a new central-type benzodiazepine receptor imaging agent (Part 1)--report on clinical usefulness in diagnosis of various brain diseases].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain; Brain Diseases; Flumazenil; GABA-A Receptor Agonists; Humans; Iodine Radioisotopes; Japan; Middle Aged; Predictive Value of Tests; Tomography, Emission-Computed, Single-Photon | 1996 |
[A phase 3 clinical trial of 123I-iomazenil, a new central-type benzodiazepine receptor imaging agent (Part 2)--Report on clinical usefulness in diagnosis of degenerative neurological diseases and mental disorders].
Topics: Adult; Aged; Brain; Female; Flumazenil; GABA-A Receptor Agonists; Humans; Iodine Radioisotopes; Japan; Male; Mental Disorders; Middle Aged; Nerve Degeneration; Nervous System Diseases; Predictive Value of Tests; Tomography, Emission-Computed, Single-Photon | 1996 |
[A phase 3 clinical trial of 123I-iomazenil, a new central-type benzodiazepine receptor imaging agent (Part 3)--Report on clinical usefulness in epilepsy].
Topics: Adult; Brain; Epilepsy; Female; Flumazenil; GABA-A Receptor Agonists; Humans; Iodine Radioisotopes; Japan; Male; Predictive Value of Tests; Tomography, Emission-Computed, Single-Photon | 1996 |
[A phase 3 clinical trial of 123I-iomazenil, a new central-type benzodiazepine receptor imaging agent (Part 4)--Report on clinical usefulness in diagnosis of cerebrovascular diseases].
Topics: Brain; Cerebrovascular Disorders; Flumazenil; GABA-A Receptor Agonists; Humans; Iodine Radioisotopes; Japan; Male; Middle Aged; Predictive Value of Tests; Tomography, Emission-Computed, Single-Photon | 1996 |
[Impairment of benzodiazepine receptor in Parkinson's disease evaluated by 123I-iomazenil SPECT].
Topics: Aged; Aged, 80 and over; Cerebral Cortex; Female; Flumazenil; Humans; Iodine Radioisotopes; Male; Middle Aged; Parkinson Disease; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1996 |
[Phase 2 clinical study of 123I-iomazenil in various cerebral diseases: part 1--examination of injection dose and clinical indications].
Topics: Adult; Brain Diseases; Female; Flumazenil; Humans; Iodine Radioisotopes; Male; Mental Disorders; Middle Aged; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1996 |
[Phase 2 clinical study of 123I-iomazenil in various cerebral diseases: part 2--clinical evaluation of central-type benzodiazepine receptor imaging with 123I-iomazenil SPECT].
Topics: Adult; Brain Diseases; Female; Flumazenil; Humans; Iodine Radioisotopes; Male; Mental Disorders; Middle Aged; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1996 |
[Evaluation of 123I-iomazenil SPECT in patients with ischemic cerebrovascular disease: comparative study with 123I-IMP SPECT].
Topics: Adult; Aged; Amphetamines; Brain; Cerebrovascular Disorders; Female; Flumazenil; Humans; Iodine Radioisotopes; Iofetamine; Male; Middle Aged; Nerve Degeneration; Neurons; Radionuclide Imaging; Regional Blood Flow | 1996 |
[Assessment of cerebral benzodiazepine receptor distribution in anxiety disorders by 123I-iomazenil-SPECT: comparison to cerebral perfusion scintigraphy by 123I-IMP].
Topics: Amphetamines; Anxiety Disorders; Brain; Cerebrovascular Circulation; Female; Flumazenil; Humans; Iodine Radioisotopes; Iofetamine; Male; Middle Aged; Perfusion; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1997 |
[Assessment of cerebral benzodiazepine receptor distribution in epilepsy by 123I-iomazenil-SPECT].
Topics: Adult; Amphetamines; Brain; Cerebrovascular Circulation; Epilepsy; Female; Flumazenil; Humans; Iodine Radioisotopes; Iofetamine; Male; Middle Aged; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1997 |
Comparison of [18F]FDG-PET, [99mTc]-HMPAO-SPECT, and [123I]-iomazenil-SPECT in localising the epileptogenic cortex.
Topics: Adolescent; Adult; Atrophy; Cerebral Cortex; Electroencephalography; Epilepsy; Female; Flumazenil; Fluorodeoxyglucose F18; Glucose; Humans; Magnetic Resonance Imaging; Male; Radiopharmaceuticals; Technetium Tc 99m Exametazime; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1997 |
Cognitive functioning and GABAA/benzodiazepine receptor binding in schizophrenia: a 123I-iomazenil SPET study.
Topics: Adult; Cognition; Female; Flumazenil; Humans; Image Processing, Computer-Assisted; Iodine Radioisotopes; Male; Neuropsychological Tests; Psychiatric Status Rating Scales; Psychomotor Performance; Receptors, GABA-A; Schizophrenia; Schizophrenic Psychology; Tomography, Emission-Computed, Single-Photon | 1998 |
Changes of benzodiazepine receptors during chronic benzodiazepine administration in humans.
Topics: Administration, Oral; Adult; Alprazolam; Anti-Anxiety Agents; Female; Flumazenil; Humans; Iodine Radioisotopes; Male; Middle Aged; Neuropsychological Tests; Receptors, GABA-A; Reproducibility of Results; Tomography, Emission-Computed, Single-Photon; Treatment Outcome; Verbal Learning | 1999 |
Brain uptake of iomazenil in cirrhotic patients: a single photon emission tomography study.
Topics: Adult; Brain; Female; Flumazenil; Humans; Iodine Radioisotopes; Liver Cirrhosis; Liver Function Tests; Male; Tomography, Emission-Computed, Single-Photon | 1999 |
Evaluation of the reference tissue models for PET and SPECT benzodiazepine binding parameters.
Topics: Adult; Algorithms; Brain; Brain Chemistry; Computer Simulation; Female; Flumazenil; Humans; Image Interpretation, Computer-Assisted; Image Processing, Computer-Assisted; Iodine Radioisotopes; Ligands; Male; Pons; Radiopharmaceuticals; Receptors, GABA-A; Reference Standards; Reference Values; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 2002 |
Experience with 123I-iomazenil SPECT in acute cerebral infarction.
Topics: Adult; Aged; Aged, 80 and over; Cerebral Infarction; Data Interpretation, Statistical; Female; Flumazenil; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Radiopharmaceuticals; Receptors, GABA-A; Sterilization, Reproductive; Stroke; Thrombolytic Therapy; Tomography, Emission-Computed, Single-Photon | 2002 |
Central type benzodiazepine receptors in Gulf War veterans with posttraumatic stress disorder.
Topics: Adult; Combat Disorders; Female; Flumazenil; Humans; Iodine Radioisotopes; Life Change Events; Male; Matched-Pair Analysis; Prefrontal Cortex; Receptors, GABA-A; Reference Values; Stress Disorders, Post-Traumatic; Tomography, Emission-Computed, Single-Photon; United States; Veterans | 2004 |
Evaluation of the use of a standard input function for compartment analysis of [123I]iomazenil data: factors influencing the quantitative results.
Topics: Adolescent; Adult; Aged; Algorithms; Alzheimer Disease; Brain; Cerebrovascular Disorders; Epilepsy; Female; Flumazenil; Humans; Image Interpretation, Computer-Assisted; Male; Middle Aged; Radioisotope Dilution Technique; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon | 2004 |
gamma-Aminobutyric acid-serotonin interactions in healthy men: implications for network models of psychosis and dissociation.
Topics: Analysis of Variance; Anxiety; Cross-Over Studies; Dissociative Disorders; Double-Blind Method; Drug Synergism; Flumazenil; GABA Modulators; gamma-Aminobutyric Acid; Humans; Male; Models, Neurological; Perceptual Disorders; Piperazines; Psychoses, Substance-Induced; Receptors, GABA-A; Receptors, Serotonin, 5-HT2; Reference Values; Serotonin; Serotonin Receptor Agonists | 2006 |
Pre-surgical identification of epileptogenic areas in temporal lobe epilepsy by 123I-iomazenil SPECT: a comparison with IMP SPECT and FDG PET.
Topics: Adolescent; Adult; Epilepsy, Temporal Lobe; Female; Flumazenil; Fluorodeoxyglucose F18; Humans; Iodine Radioisotopes; Iofetamine; Male; Positron-Emission Tomography; Preoperative Care; Prognosis; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon | 2006 |
S-ketamine and GABA-A-receptor interaction in humans: an exploratory study with I-123-iomazenil SPECT.
Topics: Adult; Analysis of Variance; Anesthetics, Dissociative; Brain Mapping; Brief Psychiatric Rating Scale; Case-Control Studies; Cerebral Cortex; Female; Flumazenil; Humans; Hydrocortisone; Iodine Radioisotopes; Ketamine; Male; Prolactin; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon; Young Adult | 2008 |
Probing GABA receptor function in schizophrenia with iomazenil.
Topics: Adult; Analysis of Variance; Anxiety; Brief Psychiatric Rating Scale; Double-Blind Method; Flumazenil; Humans; Iodine Radioisotopes; Male; Middle Aged; Receptors, GABA; Schizophrenia | 2011 |
Combination of preoperative cerebral blood flow and 123I-iomazenil SPECT imaging predicts postoperative cognitive improvement in patients undergoing uncomplicated endarterectomy for unilateral carotid stenosis.
Topics: Adult; Aged; Carotid Stenosis; Cerebrovascular Circulation; Cognition; Combined Modality Therapy; Endarterectomy, Carotid; Female; Flumazenil; Humans; Iodine Radioisotopes; Male; Middle Aged; Postoperative Care; Preoperative Care; Stereotaxic Techniques; Tomography, Emission-Computed, Single-Photon | 2012 |
Diagnostic imaging of higher brain dysfunction in patients with adult moyamoya disease using statistical imaging analysis for [123I]iomazenil single photon emission computed tomography.
Topics: Adult; Brain Infarction; Cerebral Cortex; Data Interpretation, Statistical; Female; Flumazenil; Humans; Image Processing, Computer-Assisted; Iodine Radioisotopes; Male; Middle Aged; Moyamoya Disease; Pilot Projects; Tomography, Emission-Computed, Single-Photon | 2012 |
GABA Deficits Enhance the Psychotomimetic Effects of Δ9-THC.
Topics: Adolescent; Adult; Brain Mapping; Dissociative Disorders; Double-Blind Method; Dronabinol; Electroencephalography; Event-Related Potentials, P300; Flumazenil; gamma-Aminobutyric Acid; Humans; Male; Pain Measurement; Psychiatric Status Rating Scales; Psychotic Disorders; Psychotropic Drugs; Young Adult | 2015 |
Role of GABA Deficit in Sensitivity to the Psychotomimetic Effects of Amphetamine.
Topics: Adolescent; Adult; Amphetamine; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Flumazenil; gamma-Aminobutyric Acid; Hallucinogens; Healthy Volunteers; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Psychotic Disorders; Time Factors; Visual Analog Scale; Young Adult | 2015 |
191 other study(ies) available for flumazenil and ro 16-0154
| Article | Year |
|---|---|
[Results of displacement studies on benzodiazepine receptors (123I-iomazenil and flumazenil)].
Topics: Flumazenil; Hepatic Encephalopathy; Humans; Iodine Radioisotopes; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1992 |
"Central" and "peripheral" benzodiazepine receptors: opposite changes in human epileptogenic tissue.
Topics: Adult; Autoradiography; Epilepsy, Temporal Lobe; Female; Flumazenil; Hippocampus; Humans; Male; Receptors, GABA-A; Sclerosis; Tomography, Emission-Computed, Single-Photon | 1992 |
123I-iomazenil: a quantitative study of the central benzodiazepine receptor distribution.
Topics: Adult; Aged; Amygdala; Epilepsy, Temporal Lobe; Female; Flumazenil; Hippocampus; Humans; Iodine Radioisotopes; Male; Middle Aged; Organotechnetium Compounds; Oximes; Receptors, GABA-A; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon | 1992 |
[Cortical dysplasia as an epileptogenic focus: reduced binding of 123I-iomezanil with barely perceptible 99mTc-HMPAO SPECT].
Topics: Cerebral Cortex; Epilepsies, Partial; Female; Flumazenil; Humans; Iodine Radioisotopes; Middle Aged; Organotechnetium Compounds; Oximes; Receptors, GABA-A; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon | 1992 |
Pharmacokinetics of the SPECT benzodiazepine receptor radioligand [123I]iomazenil in human and non-human primates.
Topics: Adult; Animals; Female; Flumazenil; Humans; Iodine Radioisotopes; Male; Papio; Protein Binding; Receptors, GABA-A; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 1992 |
Benzodiazepine receptors and cerebral blood flow in partial epilepsy.
Topics: Adult; Brain; Cerebrovascular Circulation; Epilepsy, Temporal Lobe; Female; Flumazenil; Humans; Iodine Radioisotopes; Male; Organotechnetium Compounds; Oximes; Receptors, GABA-A; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon | 1991 |
SPECT imaging of the benzodiazepine receptor in non-human primate brain with [123I]Ro 16-0154.
Topics: Animals; Brain; Female; Flumazenil; Injections, Intravenous; Iodine Radioisotopes; Kinetics; Macaca mulatta; Male; Papio; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1991 |
SPECT imaging of the benzodiazepine receptor: feasibility of in vivo potency measurements from stepwise displacement curves.
Topics: Alprazolam; Animals; Benzodiazepines; Brain; Brain Chemistry; Clonazepam; Diazepam; Female; Flumazenil; Injections, Intravenous; Macaca mulatta; Male; Papio; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1991 |
Identification of the side of epileptic focus with 123I-Iomazenil SPECT. A comparison with 18FDG-PET and ictal EEG findings in patients with medically intractable complex partial seizures.
Topics: Adult; Blood Glucose; Deoxyglucose; Dominance, Cerebral; Electroencephalography; Epilepsy, Temporal Lobe; Evoked Potentials; Female; Flumazenil; Fluorodeoxyglucose F18; Humans; Iodine Radioisotopes; Male; Receptors, GABA-A; Temporal Lobe; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1990 |
In vitro and in vivo evaluation of iodine-123-Ro 16-0154: a new imaging agent for SPECT investigations of benzodiazepine receptors.
Topics: Animals; Brain; Cerebrovascular Circulation; Drug Stability; Epilepsy; Female; Flumazenil; Humans; In Vitro Techniques; Iodine Radioisotopes; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 1990 |
Receptor binding characterization of the benzodiazepine radioligand 125I-Ro16-0154: potential probe for SPECT brain imaging.
Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Cerebral Cortex; Flumazenil; gamma-Aminobutyric Acid; Humans; Iodine Radioisotopes; Kidney; Kinetics; Macaca mulatta; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sodium Chloride; Tomography, Emission-Computed, Single-Photon | 1990 |
Imaging benzodiazepine receptors in the human brain by single photon emission computed tomography (SPECT).
Topics: Adult; Animals; Brain; Female; Flumazenil; Humans; Iodine Radioisotopes; Male; Middle Aged; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 1989 |
Dual-tracer autoradiography using 125I-iomazenil and 99Tcm-HMPAO in experimental brain ischaemia.
Topics: Acute Disease; Animals; Autoradiography; Brain; Brain Ischemia; Chronic Disease; Flumazenil; Functional Laterality; Iodine Radioisotopes; Male; Organ Specificity; Organotechnetium Compounds; Oximes; Radionuclide Imaging; Rats; Rats, Inbred Strains; Receptors, GABA-A; Technetium Tc 99m Exametazime | 1995 |
Central benzodiazepine receptor distribution after subcortical hemorrhage evaluated by means of [123I]iomazenil and SPECT.
Topics: Cerebral Cortex; Cerebral Hemorrhage; Female; Flumazenil; Humans; Iodine Radioisotopes; Male; Middle Aged; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1995 |
[125I]iomazenil binding in the brains of spontaneously epileptic rats: an ex vivo quantitative autoradiographic study.
Topics: Animals; Autoradiography; Brain; Cerebrovascular Circulation; Epilepsy; Flumazenil; Iodine Radioisotopes; Kinetics; Male; Organ Specificity; Rats; Rats, Inbred WKY; Rats, Mutant Strains; Receptors, GABA-A; Species Specificity; Time Factors | 1995 |
Role of I-123-iomazenil SPECT imaging in drug resistant epilepsy with complex partial seizures.
Topics: Adolescent; Adult; Anticonvulsants; Cerebral Cortex; Drug Therapy, Combination; Electroencephalography; Epilepsy, Complex Partial; Evoked Potentials; Female; Flumazenil; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Iodine Radioisotopes; Male; Middle Aged; Receptors, GABA-A; Temporal Lobe; Tomography, Emission-Computed, Single-Photon | 1995 |
Neuroreceptor quantification in vivo by the steady state principle and [123I]iomazenil in rats.
Topics: Animals; Blood; Brain; Flumazenil; Male; Mathematics; Neurons; Rats; Rats, Wistar; Receptors, GABA-A | 1995 |
Abnormal regional benzodiazepine receptor uptake in the prefrontal cortex in patients with panic disorder.
Topics: Female; Flumazenil; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; Male; Panic Disorder; Prefrontal Cortex; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1995 |
Hyperfixation of 99mTc-HMPAO and hypofixation of 123I-iomazenil in acute herpes encephalitis.
Topics: Brain; Encephalitis; Encephalitis Viruses; Female; Flumazenil; Herpes Simplex; Humans; Iodine Radioisotopes; Middle Aged; Organotechnetium Compounds; Oximes; Receptors, GABA-A; Technetium Tc 99m Exametazime; Temporal Lobe; Tomography, Emission-Computed, Single-Photon | 1995 |
A potential use of a 123I-labelled benzodiazepine receptor antagonist as a predictor of neuronal cell viability: comparisons with 14C-labelled 2-deoxyglucose autoradiography and histopathological examination.
Topics: Animals; Autoradiography; Brain; Carbon Radioisotopes; Cell Survival; Cerebral Infarction; Cerebrovascular Disorders; Deoxyglucose; Flumazenil; Gerbillinae; Humans; Iodine Radioisotopes; Neurons; Predictive Value of Tests; Receptors, GABA-A; Tomography, Emission-Computed | 1995 |
In vivo imaging of GABAA receptors using sequential whole-volume iodine-123 iomazenil single-photon emission tomography.
Topics: Adult; Brain; Brain Chemistry; Feasibility Studies; Female; Flumazenil; Humans; Image Processing, Computer-Assisted; Iodine Radioisotopes; Male; Pilot Projects; Receptors, GABA-A; Time Factors; Tomography, Emission-Computed, Single-Photon | 1995 |
Changes of central benzodiazepine receptor density in the course of anticonvulsant treatment in temporal lobe epilepsy.
Topics: Adult; Brain Mapping; Carbamazepine; Epilepsy, Temporal Lobe; Female; Flumazenil; Humans; Image Processing, Computer-Assisted; Radioligand Assay; Receptors, GABA-A; Temporal Lobe; Tomography, Emission-Computed, Single-Photon | 1995 |
Simple quantification of benzodiazepine receptor binding and ligand transport using iodine-123-iomazenil and two SPECT scans.
Topics: Adult; Benzodiazepines; Brain; Flumazenil; Humans; Iodine Radioisotopes; Male; Middle Aged; Receptors, Drug; Tomography, Emission-Computed, Single-Photon | 1995 |
Reproducibility of SPECT measurement of benzodiazepine receptors in human brain with iodine-123-iomazenil.
Topics: Adult; Brain; Female; Flumazenil; Humans; Iodine Radioisotopes; Male; Receptors, GABA-A; Reproducibility of Results; Tomography, Emission-Computed, Single-Photon | 1995 |
Decreased benzodiazepine receptor binding in panic disorder measured by IOMAZENIL-SPECT. A preliminary report.
Topics: Adult; Cerebral Ventricles; Female; Flumazenil; Frontal Lobe; Humans; Male; Occipital Lobe; Panic Disorder; Psychiatric Status Rating Scales; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1994 |
Evaluation of ultrafiltration for the free-fraction determination of single photon emission computed tomography (SPECT) radiotracers: beta-CIT, IBF, and iomazenil.
Topics: Adsorption; Benzofurans; Blood Proteins; Cocaine; Dialysis; Evaluation Studies as Topic; Flumazenil; Humans; Iodine Radioisotopes; Membranes, Artificial; Protein Binding; Pyrrolidines; Reproducibility of Results; Temperature; Tomography, Emission-Computed, Single-Photon; Ultrafiltration | 1994 |
Comparison of benzodiazepine receptor and regional cerebral blood flow imaging of epileptiform foci in hippocampal kindled rabbits: a study with in vivo double tracer autoradiography using 125I-iomazenil and 99mTc-HMPAO.
Topics: Animals; Autoradiography; Cerebrovascular Circulation; Flumazenil; Hippocampus; Iodine Radioisotopes; Kindling, Neurologic; Male; Organotechnetium Compounds; Oximes; Rabbits; Receptors, GABA-A; Technetium Tc 99m Exametazime | 1994 |
Comparison of benzodiazepine receptor and regional cerebral blood flow imaging of epileptiform foci in hippocampal kindled rabbits: a preliminary report.
Topics: Animals; Autoradiography; Cerebrovascular Circulation; Epilepsy; Flumazenil; Hippocampus; Iodine Radioisotopes; Kindling, Neurologic; Male; Rabbits; Receptors, GABA-A; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1994 |
Human biodistribution and dosimetry of the SPECT benzodiazepine receptor radioligand iodine-123-iomazenil.
Topics: Adult; Brain; Female; Flumazenil; Humans; Image Processing, Computer-Assisted; Iodine Radioisotopes; Male; Radiation Dosage; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 1994 |
[123I-iomazenil- and 99mTc-HMPAO in the diagnosis of focal epilepsies: a comparison of untreated and treated patients].
Topics: Adolescent; Adult; Epilepsies, Partial; Female; Flumazenil; Humans; Iodine Radioisotopes; Male; Middle Aged; Organotechnetium Compounds; Oximes; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon | 1994 |
SPECT quantification of [123I]iomazenil binding to benzodiazepine receptors in nonhuman primates: I. Kinetic modeling of single bolus experiments.
Topics: Animals; Blood; Brain; Computer Simulation; Flumazenil; Iodine Radioisotopes; Kinetics; Models, Biological; Papio; Receptors, GABA-A; Reproducibility of Results; Time Factors; Tomography, Emission-Computed, Single-Photon | 1994 |
SPECT quantification of [123I]iomazenil binding to benzodiazepine receptors in nonhuman primates: II. Equilibrium analysis of constant infusion experiments and correlation with in vitro parameters.
Topics: Animals; Blood; Female; Flumazenil; Homeostasis; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Papio; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1994 |
Dual-isotope autoradiographic measurement of regional blood flow and benzodiazepine receptor availability following unilateral middle cerebral artery occlusion.
Topics: Amphetamines; Animals; Autoradiography; Brain; Brain Ischemia; Cerebral Arteries; Flumazenil; Iodine Radioisotopes; Iofetamine; Radiography; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Regional Blood Flow; Tomography, Emission-Computed, Single-Photon | 1994 |
Benzodiazepine receptor equilibrium constants for flumazenil and midazolam determined in humans with the single photon emission computer tomography tracer [123I]iomazenil.
Topics: Adolescent; Adult; Binding Sites; Blood Proteins; Chromatography, High Pressure Liquid; Flumazenil; Humans; Male; Midazolam; Protein Binding; Receptors, GABA-A | 1993 |
Formation of 1-[123I]iodobutane in labeling [123I]iomazenil by iododestannylation: implications for the reaction mechanism.
Topics: Butanes; Flumazenil; Iodine Radioisotopes; Isotope Labeling | 1994 |
SPECT measurement of benzodiazepine receptors in human brain with iodine-123-iomazenil: kinetic and equilibrium paradigms.
Topics: Adult; Brain Chemistry; Female; Flumazenil; Humans; Iodine Radioisotopes; Kinetics; Male; Receptors, GABA-A; Reference Values; Tomography, Emission-Computed, Single-Photon | 1994 |
Dosimetry of iodine-123 iomazenil in humans.
Topics: Adult; Epilepsies, Partial; Flumazenil; Humans; Iodine Radioisotopes; Male; Middle Aged; Radiometry; Radionuclide Imaging; Tissue Distribution | 1993 |
Single photon emission tomography measurement of benzodiazepine receptor number and affinity in primate brain: a constant infusion paradigm with [123I]iomazenil.
Topics: Animals; Brain Chemistry; Flumazenil; In Vitro Techniques; Iodine Radioisotopes; Papio; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1993 |
[Central type benzodiazepine receptor and cerebral blood flow in experimental chronic brain infarction--evaluation using a double-tracer autoradiography technique].
Topics: Animals; Autoradiography; Brain; Cerebral Infarction; Cerebrovascular Circulation; Chronic Disease; Flumazenil; Iodine Radioisotopes; Male; Organotechnetium Compounds; Oximes; Radionuclide Imaging; Rats; Rats, Inbred Strains; Receptors, GABA-A; Technetium Tc 99m Exametazime | 1993 |
[123I]iomazenil SPECT imaging demonstrates significant benzodiazepine receptor reserve in human and nonhuman primate brain.
Topics: Adult; Animals; Binding, Competitive; Brain; Dialysis; Female; Flumazenil; gamma-Aminobutyric Acid; Half-Life; Humans; Hypnotics and Sedatives; Iodine Radioisotopes; Lorazepam; Male; Nipecotic Acids; Ovariectomy; Papio; Receptors, GABA-A; Tiagabine; Tomography, Emission-Computed, Single-Photon | 1993 |
Quantification of central benzodiazepine receptor binding potential in the brain with 123I-iomazenil SPECT: technical and interobserver variability.
Topics: Adult; Brain; Female; Flumazenil; Humans; Iodine Radioisotopes; Male; Middle Aged; Models, Structural; Observer Variation; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1993 |
[In vivo autoradiographic benzodiazepine receptor imaging with 125I-iomazenil (Ro 16-0154)].
Topics: Animals; Autoradiography; Binding, Competitive; Brain; Flumazenil; Gerbillinae; Iodine Radioisotopes; Male; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1993 |
Evaluation of cerebral infarction with iodine 123-iomazenil SPECT.
Topics: Aphasia, Broca; Aphasia, Wernicke; Brain; Cerebral Infarction; Cerebrovascular Circulation; Female; Flumazenil; Humans; Iodine Radioisotopes; Male; Middle Aged; Oxygen Consumption; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1995 |
Ultra-high resolution SPECT system using four pinhole collimators for small animal studies.
Topics: Animals; Animals, Laboratory; Brain; Equipment Design; Flumazenil; Heart; Image Processing, Computer-Assisted; Iodine Radioisotopes; Male; Organotechnetium Compounds; Oximes; Phantoms, Imaging; Rats; Rats, Wistar; Technetium Tc 99m Exametazime; Technetium Tc 99m Sestamibi; Tomography, Emission-Computed, Single-Photon | 1995 |
[Pharmacokinetics of 123I-iomazenil, a benzodiazepine receptor seeker].
Topics: Animals; Flumazenil; Humans; Iodine Radioisotopes; Male; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Tissue Distribution | 1995 |
A reappraisal of the relative merits of SPET and PET in the quantitation of neuroreceptors: the advantage of a longer half-life!
Topics: Animals; Brain; Carbon Radioisotopes; Flumazenil; GABA Modulators; Half-Life; Humans; Iodine Radioisotopes; Receptors, GABA-A; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1996 |
Carbon-11 and iodine-123 labelled iomazenil: a direct PET-SPET compari son.
Topics: Adult; Brain; Carbon Radioisotopes; Flumazenil; GABA Modulators; Humans; Iodine Radioisotopes; Receptors, GABA-A; Time Factors; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1996 |
Reduced GABAA receptor density contralateral to a potentially epileptogenic MRI abnormality in a patient with complex partial seizures.
Topics: Adult; Arachnoid Cysts; Electroencephalography; Epilepsy, Complex Partial; Female; Flumazenil; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; Receptors, GABA-A; Temporal Lobe; Tomography, Emission-Computed, Single-Photon | 1996 |
A simple method for the quantification of benzodiazepine receptors using iodine-123 iomazenil and single-photon emission tomography.
Topics: Brain; Brain Neoplasms; Cerebrovascular Disorders; Computer Simulation; Dementia; Flumazenil; Humans; Iodine Radioisotopes; Middle Aged; Receptors, GABA-A; Reproducibility of Results; Tomography, Emission-Computed, Single-Photon | 1996 |
Noninvasive quantification of iodine-123-iomazenil SPECT.
Topics: Adult; Blood Specimen Collection; Brain; Feasibility Studies; Flumazenil; Humans; Iodine Radioisotopes; Male; Middle Aged; Receptors, GABA-A; Reference Values; Time Factors; Tomography, Emission-Computed, Single-Photon | 1996 |
Modeling alternatives for cerebral carbon-11-iomazenil kinetics.
Topics: Adult; Brain; Carbon Radioisotopes; Flumazenil; Humans; Models, Theoretical; Receptors, GABA-A; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1996 |
Tracer kinetic modelling of receptor data with mathematical metabolite correction.
Topics: Adult; Brain; Carbon Radioisotopes; Computer Simulation; Feasibility Studies; Flumazenil; Humans; Models, Theoretical; Monte Carlo Method; Receptors, GABA-A; Tomography, Emission-Computed | 1996 |
Decrease in benzodiazepine receptor binding in a patient with Angelman syndrome detected by iodine-123 iomazenil and single-photon emission tomography.
Topics: Adult; Amphetamines; Angelman Syndrome; Brain; Cerebrovascular Circulation; Female; Flumazenil; Humans; Iodine Radioisotopes; Iofetamine; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1996 |
Reduced cortical distribution volume of iodine-123 iomazenil in Alzheimer's disease as a measure of loss of synapses.
Topics: Alzheimer Disease; Case-Control Studies; Cerebral Cortex; Female; Flumazenil; Humans; Iodine Radioisotopes; Male; Middle Aged; Pilot Projects; Receptors, GABA-A; Synapses; Tomography, Emission-Computed, Single-Photon | 1996 |
[Benzodiazepine receptor and cerebral blood flow in early Alzheimer's disease--SPECT study using 123I-iomazenil and 123I-IMP].
Topics: Aged; Alzheimer Disease; Amphetamines; Brain; Cerebrovascular Circulation; Female; Flumazenil; Humans; Iodine Radioisotopes; Iofetamine; Middle Aged; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1996 |
Delayed image of iodine-123 iomazenil as a relative map of benzodiazepine receptor binding: the optimal scan time.
Topics: Alzheimer Disease; Brain; Case-Control Studies; Cerebral Infarction; Computer Simulation; Dementia, Vascular; Flumazenil; Humans; Iodine Radioisotopes; Male; Parkinson Disease; Receptors, GABA-A; Time Factors; Tomography, Emission-Computed, Single-Photon | 1996 |
Reduction of 123I-iomazenil uptake in haemodynamically and metabolically impaired brain areas in patients with cerebrovascular disease.
Topics: Aged; Cerebrovascular Circulation; Cerebrovascular Disorders; Flumazenil; Humans; Iodine Radioisotopes; Ligands; Male; Middle Aged; Oxygen Consumption; Receptors, GABA-A; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1996 |
The effects of single and repeated phencyclidine administration on [125I] iomazenil binding in the rat brain.
Topics: Animals; Autoradiography; Brain; Excitatory Amino Acid Antagonists; Flumazenil; Iodine Radioisotopes; Male; Phencyclidine; Rats; Rats, Wistar; Synaptic Transmission | 1996 |
[Parametric images of central-type benzodiazepine receptor binding and ligand transport by two SPECT scans of 123I-iomazenil: relative quantification without blood data].
Topics: Biological Transport; Brain; Flumazenil; Humans; Iodine Radioisotopes; Ligands; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1996 |
Correlation between reduced in vivo benzodiazepine receptor binding and severity of psychotic symptoms in schizophrenia.
Topics: Adolescent; Adult; Cerebral Cortex; Female; Flumazenil; Frontal Lobe; gamma-Aminobutyric Acid; Humans; Male; Psychiatric Status Rating Scales; Receptors, GABA-A; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index; Temporal Lobe; Tomography, Emission-Computed, Single-Photon | 1997 |
Incomplete brain infarction of reperfused cortex may be quantitated with iomazenil.
Topics: Aged; Cerebellum; Cerebral Cortex; Cerebral Infarction; Cerebrovascular Circulation; Female; Flumazenil; Humans; Intracranial Embolism and Thrombosis; Iodine Radioisotopes; Magnetic Resonance Imaging; Male; Middle Aged; Models, Theoretical; Organotechnetium Compounds; Oximes; Receptors, GABA-A; Reperfusion; Technetium Tc 99m Exametazime; Time Factors; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; Xenon Radioisotopes | 1997 |
Decrease of the central type benzodiazepine receptor in cortical tubers in a patient with tuberous sclerosis.
Topics: Adolescent; Cerebral Cortex; Flumazenil; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; Male; Radiopharmaceuticals; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon; Tuberous Sclerosis | 1997 |
Presurgical identification of epileptic foci with iodine-123 iomazenil SPET: comparison with brain perfusion SPET and FDG PET.
Topics: Adult; Brain; Deoxyglucose; Electroencephalography; Epilepsy, Frontal Lobe; Epilepsy, Temporal Lobe; Feasibility Studies; Female; Flumazenil; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; Male; Middle Aged; Preoperative Care; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1997 |
Is 11C-flumazenil PET superior to 18FDG PET and 123I-iomazenil SPECT in presurgical evaluation of temporal lobe epilepsy?
Topics: Adolescent; Adult; Carbon Radioisotopes; Deoxyglucose; Electroencephalography; Epilepsy, Temporal Lobe; Female; Flumazenil; Fluorine Radioisotopes; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; Male; Middle Aged; Preoperative Care; Temporal Lobe; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1997 |
Comparison of iodine-123-iomazenil SPECT and technetium-99m-HMPAO-SPECT in Alzheimer's disease.
Topics: Alzheimer Disease; Brain; Female; Flumazenil; Humans; Image Processing, Computer-Assisted; Iodine Radioisotopes; Male; Middle Aged; Organotechnetium Compounds; Oximes; Technetium Tc 99m Exametazime; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 1997 |
123I-iomazenil as a clinical tool for studying neuronal loss.
Topics: Alzheimer Disease; Cerebral Cortex; Flumazenil; Humans; Iodine Radioisotopes; Male; Middle Aged; Receptors, GABA-A; Synapses; Tomography, Emission-Computed, Single-Photon | 1997 |
Benzodiazepine receptor distribution and diazepam binding in schizophrenia: an exploratory study.
Topics: Adult; Benzodiazepines; Binding Sites; Chronic Disease; Diazepam; Flumazenil; Frontal Lobe; Growth Hormone; Humans; Hydrocortisone; Occipital Lobe; Receptors, GABA-A; Schizophrenia; Temporal Lobe; Tomography, Emission-Computed, Single-Photon | 1997 |
A method for the quantification of benzodiazepine receptors by using 123I-iomazenil and SPECT with one scan and one blood sampling.
Topics: Adult; Aged; Autoradiography; Brain; Brain Neoplasms; Cerebrovascular Disorders; Computer Simulation; Dementia; Evaluation Studies as Topic; Flumazenil; Humans; Iodine Radioisotopes; Middle Aged; Models, Biological; Nonlinear Dynamics; Receptors, GABA-A; Reproducibility of Results; Tomography, Emission-Computed, Single-Photon | 1997 |
[Compartment analysis of 123I-iomazenil brain on early and delayed SPECT].
Topics: Adult; Brain; Brain Diseases; Cerebrovascular Circulation; Female; Flumazenil; Humans; Iodine Radioisotopes; Male; Middle Aged; Models, Biological; Radiopharmaceuticals; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1997 |
Pharmacokinetic analysis of benzodiazepine receptor binding of [123I]iomazenil in human brain.
Topics: Blood-Brain Barrier; Brain; Brain Diseases; Flumazenil; Humans; Injections, Intravenous; Iodine Radioisotopes; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1997 |
Mechanism of reduction of cortical blood flow in striatocapsular infarction: studies using [123I]iomazenil SPECT.
Topics: Aphasia; Basal Ganglia; Cerebral Cortex; Cerebral Infarction; Cerebrovascular Circulation; Female; Flumazenil; Hemiplegia; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; Male; Middle Aged; Neostriatum; Radionuclide Imaging; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon | 1997 |
Assessment of benzodiazepine receptors using iodine-123-labeled iomazenil single-photon emission computed tomography in patients with ischemic cerebrovascular disease. A comparison with PET study.
Topics: Aged; Brain; Brain Ischemia; Flumazenil; Humans; Iodine Radioisotopes; Male; Middle Aged; Radiography; Receptors, GABA-A; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1997 |
125I-iomazenil binding shows stress- and/or diazepam-induced reductions in mouse brain: supporting data for 123I-iomazenil SPECT study of anxiety disorders.
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Autoradiography; Brain; Diazepam; Flumazenil; Iodine Radioisotopes; Male; Mice; Mice, Inbred ICR; Stress, Physiological; Tomography, Emission-Computed, Single-Photon | 1997 |
Benzodiazepine receptor binding and schizophrenia.
Topics: Flumazenil; Frontal Lobe; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Prefrontal Cortex; Receptors, GABA-A; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index; Tomography, Emission-Computed, Single-Photon | 1997 |
Benzodiazepine receptors in chronic cerebrovascular disease: comparison with blood flow and metabolism.
Topics: Brain; Cerebral Infarction; Cerebrovascular Circulation; Female; Flumazenil; Humans; Iodine Radioisotopes; Male; Middle Aged; Moyamoya Disease; Radiopharmaceuticals; Receptors, GABA-A; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon | 1997 |
I-123 iomazenil SPECT in patients with mental disorders.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Brain; Female; Flumazenil; Humans; Iodine Radioisotopes; Male; Mental Disorders; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon | 1997 |
Quantitative estimation of I-123-Iomazenil receptor binding in temporal lobe epilepsies using two SPECT acquisitions--comparison with the regional cerebral blood flow and a compartment model.
Topics: Adult; Brain; Cerebrovascular Circulation; Electroencephalography; Epilepsy, Temporal Lobe; Female; Flumazenil; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; Male; Models, Neurological; Radiopharmaceuticals; Receptors, GABA-A; Regression Analysis; Technetium Tc 99m Exametazime; Temporal Lobe; Tomography, Emission-Computed, Single-Photon; Video Recording | 1998 |
Decrease in benzodiazepine receptor binding in the brains of adult patients with Rett syndrome.
Topics: Adult; Brain; Case-Control Studies; Female; Flumazenil; Humans; Male; Radioligand Assay; Receptors, GABA-A; Rett Syndrome; Synaptic Transmission; Tomography, Emission-Computed, Single-Photon | 1998 |
Iodine-123-iomazenil SPECT in Alzheimer's disease.
Topics: Alzheimer Disease; Flumazenil; Humans; Iodine Radioisotopes; Radiopharmaceuticals; Sensitivity and Specificity; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon | 1998 |
Brain SPECT imaging using three different tracers in subacute cerebral infarction.
Topics: Adult; Brain; Cerebellum; Cerebral Infarction; Cerebrovascular Circulation; Cysteine; Female; Flumazenil; Humans; Iodine Radioisotopes; Male; Middle Aged; Organotechnetium Compounds; Radiopharmaceuticals; Receptors, GABA-A; Technetium Tc 99m Exametazime; Temporal Lobe; Tissue Survival; Tomography, Emission-Computed, Single-Photon | 1998 |
Iodine-123-iomazenil and iodine-123-iodoamphetamine SPECT in major cerebral artery occlusive disease.
Topics: Amphetamines; Brain; Brain Ischemia; Carotid Stenosis; Case-Control Studies; Cerebrovascular Circulation; Cerebrovascular Disorders; Feasibility Studies; Female; Flumazenil; Humans; Iodine Radioisotopes; Iofetamine; Magnetic Resonance Imaging; Male; Middle Aged; Tomography, Emission-Computed, Single-Photon | 1998 |
Decreased benzodiazepine receptor binding in Machado-Joseph disease.
Topics: Adult; Brain; Case-Control Studies; Flumazenil; Humans; Iodine Radioisotopes; Machado-Joseph Disease; Male; Middle Aged; Radiopharmaceuticals; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1998 |
Asymmetries of benzodiazepine receptor binding potential in the inferior medial temporal lobe and cerebellum detected with 123I-iomazenil SPECT in comparison with 99mTc-HMPAO SPECT in patients with partial epilepsy.
Topics: Adult; Cerebellum; Epilepsies, Partial; Female; Flumazenil; Humans; Iodine Radioisotopes; Male; Middle Aged; Radiopharmaceuticals; Receptors, GABA-A; Technetium Tc 99m Exametazime; Temporal Lobe; Tomography, Emission-Computed, Single-Photon | 1998 |
Alterations of benzodiazepine receptors in type II alcoholic subjects measured with SPECT and [123I]iomazenil.
Topics: Adult; Alcoholism; Brain; Cerebellum; Cerebral Cortex; Flumazenil; Frontal Lobe; Gyrus Cinguli; Humans; Image Processing, Computer-Assisted; Iodine Radioisotopes; Magnetic Resonance Imaging; Male; Receptors, GABA-A; Risk Factors; Tomography, Emission-Computed, Single-Photon | 1998 |
Characterization of neuronal damage by iomazenil binding and cerebral blood flow in an ischemic rat model.
Topics: Animals; Brain; Cerebrovascular Circulation; Disease Models, Animal; Flumazenil; Iodine Radioisotopes; Ischemic Attack, Transient; Male; Necrosis; Neurons; Rats; Rats, Sprague-Dawley; Time Factors; Tomography, Emission-Computed, Single-Photon | 1998 |
Single-photon emission computed tomography image of benzodiazepine receptors in a patient with Creutzfeldt-Jakob disease.
Topics: Brain; Brain Chemistry; Cerebellar Ataxia; Creutzfeldt-Jakob Syndrome; Female; Flumazenil; Humans; Middle Aged; Myoclonus; Nerve Degeneration; Nerve Tissue Proteins; Point Mutation; PrPC Proteins; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1998 |
Evaluation of neuronal loss in adult moyamoya disease by 123I-iomazenil SPECT.
Topics: Adolescent; Adult; Brain; Female; Flumazenil; Humans; Iodine Radioisotopes; Male; Middle Aged; Moyamoya Disease; Neurons; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1999 |
No evidence of altered in vivo benzodiazepine receptor binding in schizophrenia.
Topics: Adult; Flumazenil; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; Male; Middle Aged; Outcome Assessment, Health Care; Receptors, GABA-A; Schizophrenia; Tomography, Emission-Computed, Single-Photon | 1999 |
Re: I-123 iomazenil SPECT in patients with mental disorders.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Brain; Female; Flumazenil; Humans; Iodine Radioisotopes; Mental Disorders; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon | 1999 |
Discrepancy of benzodiazepine receptor occupancy between 3H-flumazenil and 125I-iomazenil in intact mouse brain.
Topics: Animals; Binding, Competitive; Brain; Carbolines; Flumazenil; Flunitrazepam; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Male; Mice; Nitrazepam; Receptors, GABA-A; Triazolam; Tritium | 1999 |
Viable tissue in an area of severely reduced perfusion demonstrated with I-123 iomazenil brain SPECT imaging of benzodiazepine receptors.
Topics: Acetazolamide; Aged; Angiography, Digital Subtraction; Brain; Carotid Artery, Internal; Carotid Stenosis; Cerebrovascular Circulation; Female; Flumazenil; Humans; Iodine Radioisotopes; Oxygen Consumption; Radiopharmaceuticals; Receptors, GABA-A; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1999 |
Blood-brain barrier transport and protein binding of flumazenil and iomazenil in the rat: implications for neuroreceptor studies.
Topics: Animals; Biological Transport; Blood-Brain Barrier; Cerebrovascular Circulation; Flumazenil; GABA Modulators; GABA-A Receptor Antagonists; Ligands; Male; Rats; Rats, Wistar | 1999 |
Comparison between cortical distribution of I-123 iomazenil and Tc-99m HMPAO in patients with Alzheimer's disease using SPECT.
Topics: Alzheimer Disease; Brain; Female; Flumazenil; Humans; Iodine Radioisotopes; Male; Middle Aged; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon | 1999 |
Decreased density of GABA-A receptors in the left sensorimotor cortex in akinetic catatonia: investigation of in vivo benzodiazepine receptor binding.
Topics: Adult; Analysis of Variance; Binding, Competitive; Catatonia; Female; Flumazenil; Humans; Male; Motor Cortex; Psychiatric Status Rating Scales; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1999 |
Benzodiazepine receptor imaging with iomazenil SPECT in aphasic patients with cerebral infarction.
Topics: Aged; Aphasia; Brain; Cerebrovascular Circulation; Female; Flumazenil; Functional Laterality; Humans; Infarction, Middle Cerebral Artery; Iodine Radioisotopes; Magnetic Resonance Imaging; Male; Middle Aged; Receptors, GABA-A; Regional Blood Flow; Tomography, Emission-Computed, Single-Photon | 1999 |
Assessment of outcome by EC/IC bypass with 123I-iomazenil brain SPECT.
Topics: Aged; Arterial Occlusive Diseases; Brain; Carotid Artery, Internal; Carotid Stenosis; Cerebral Arterial Diseases; Cerebral Infarction; Cerebral Revascularization; Flumazenil; Humans; Iodine Radioisotopes; Male; Middle Aged; Middle Cerebral Artery; Radiopharmaceuticals; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; Treatment Outcome | 1999 |
Prediction of improvement of cerebral perfusion with I-123 iomazenil SPECT.
Topics: Arterial Occlusive Diseases; Brain; Carotid Artery, Internal; Carotid Stenosis; Cerebral Arterial Diseases; Cerebral Infarction; Cerebrovascular Circulation; Endarterectomy, Carotid; Female; Flumazenil; Functional Laterality; Humans; Iodine Radioisotopes; Male; Middle Aged; Paresis; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 1999 |
Quantitation of benzodiazepine receptor binding with PET [11C]iomazenil and SPECT [123I]iomazenil: preliminary results of a direct comparison in healthy human subjects.
Topics: Adult; Binding, Competitive; Biological Assay; Brain; Flumazenil; Health Status; Humans; Male; Radioligand Assay; Radiopharmaceuticals; Receptors, GABA-A; Time Factors; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1999 |
Effects of vigabatrin on the GABAergic system as determined by [123I]iomazenil SPECT and GABA MRS.
Topics: Adult; Anticonvulsants; Female; Flumazenil; Humans; Iodine Radioisotopes; Magnetic Resonance Spectroscopy; Male; Middle Aged; Occipital Lobe; Receptors, GABA; Tomography, Emission-Computed, Single-Photon; Vigabatrin | 1999 |
Kinetic modeling of benzodiazepine receptor binding with PET and high specific activity [(11)C]Iomazenil in healthy human subjects.
Topics: Adolescent; Adult; Brain; Carbon Radioisotopes; Flumazenil; Humans; Kinetics; Male; Radioligand Assay; Receptors, GABA-A; Tomography, Emission-Computed | 2000 |
Preserved benzodiazepine receptors in Alzheimer's disease measured with C-11 flumazenil PET and I-123 iomazenil SPECT in comparison with CBF.
Topics: Aged; Alzheimer Disease; Carbon Radioisotopes; Case-Control Studies; Cerebrovascular Circulation; Evaluation Studies as Topic; Female; Flumazenil; Humans; Iodine Radioisotopes; Middle Aged; Radiopharmaceuticals; Receptors, GABA-A; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1999 |
[123I]Iomazenil SPECT benzodiazepine receptor imaging in schizophrenia.
Topics: Adult; Brain; Brain Mapping; Cerebral Cortex; Dominance, Cerebral; Female; Flumazenil; Frontal Lobe; Humans; Iodine Radioisotopes; Male; Middle Aged; Psychiatric Status Rating Scales; Receptors, GABA-A; Schizophrenia; Tomography, Emission-Computed, Single-Photon | 1999 |
[Compartment analysis of 123I-iomazenil brain SPECT in patients with moyamoya disease].
Topics: Adult; Brain; Female; Flumazenil; Humans; Male; Middle Aged; Moyamoya Disease; Tomography, Emission-Computed, Single-Photon | 1999 |
SPECT [I-123]iomazenil measurement of the benzodiazepine receptor in panic disorder.
Topics: Adolescent; Adult; Aged; Female; Flumazenil; GABA Modulators; Hippocampus; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; Male; Middle Aged; Panic Disorder; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 2000 |
Effect of chronic (-)-nicotine treatment on rat cerebral benzodiazepine receptors.
Topics: Animals; Anticonvulsants; Cerebral Cortex; Diazepam; Flumazenil; Iodine Radioisotopes; Male; Nicotine; Nicotinic Agonists; Radionuclide Imaging; Rats; Rats, Wistar; Receptors, GABA-A; Tissue Distribution | 2000 |
Detection of viable cortical neurons using benzodiazepine receptor imaging after reversible focal ischaemia in rats: comparison with regional cerebral blood flow.
Topics: Animals; Autoradiography; Brain; Brain Chemistry; Cerebrovascular Circulation; Flumazenil; Iodine Radioisotopes; Iofetamine; Ischemic Attack, Transient; Male; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Wistar; Receptors, GABA-A | 2000 |
Decreased benzodiazepine receptor binding in prefrontal cortex in combat-related posttraumatic stress disorder.
Topics: Adult; Brief Psychiatric Rating Scale; Combat Disorders; Flumazenil; Hippocampus; Humans; Iodine Radioisotopes; Male; Mesencephalon; Middle Aged; Pons; Prefrontal Cortex; Receptors, GABA-A; Thalamus; Tomography, Emission-Computed, Single-Photon; Veterans; Vietnam | 2000 |
Levels of gamma-aminobutyric acid-benzodiazepine receptors in abstinent, alcohol-dependent women: preliminary findings from an 123I-iomazenil single photon emission tomography study.
Topics: Adult; Alcoholism; Brain; Brain Chemistry; Cerebellum; Female; Flumazenil; Humans; Male; Middle Aged; Monte Carlo Method; Normal Distribution; Occipital Lobe; Parietal Lobe; Receptors, GABA-A; Sex Factors; Temperance; Tomography, Emission-Computed, Single-Photon | 2000 |
Similarity and robustness of PET and SPECT binding parameters for benzodiazepine receptors.
Topics: Adult; Brain Chemistry; Carbon Radioisotopes; Flumazenil; GABA Modulators; Humans; Iodine Radioisotopes; Models, Biological; Receptors, GABA-A; Reproducibility of Results; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 2000 |
Benzodiazepine receptor quantification in Huntington's disease with [(123)I]omazenil and SPECT.
Topics: Adult; Female; Flumazenil; Humans; Huntington Disease; Iodine Radioisotopes; Male; Middle Aged; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 2001 |
Different sensitivities to competitive inhibition of benzodiazepine receptor binding of 11C-iomazenil and 11C-flumazenil in rhesus monkey brain.
Topics: Animals; Binding, Competitive; Brain; Carbon Radioisotopes; Flumazenil; GABA-A Receptor Antagonists; Kinetics; Macaca mulatta; Radioligand Assay; Radiopharmaceuticals; Receptors, GABA-A; Tissue Distribution; Tomography, Emission-Computed | 2001 |
Disturbed benzodiazepine receptor function at the onset of temporal lobe epilepsy--lomanzenil-binding in de-novo TLE.
Topics: Adolescent; Adult; Binding Sites; Disease Progression; Epilepsy, Temporal Lobe; Female; Flumazenil; Functional Laterality; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; Male; Middle Aged; Radionuclide Imaging; Receptors, GABA-A; Seizures; Time Factors | 2001 |
SPECT and neuropsychological performance in severe depression treated with ECT.
Topics: Adult; Brain; Cerebral Cortex; Depressive Disorder, Major; Dominance, Cerebral; Electroconvulsive Therapy; Female; Flumazenil; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuropsychological Tests; Radioligand Assay; Receptors, GABA-A; Regional Blood Flow; Synaptic Transmission; Temporal Lobe; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2001 |
125I-iomazenil-benzodiazepine receptor binding during psychological stress in rats.
Topics: Animals; Brain; Electroshock; Flumazenil; Male; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Wistar; Receptors, GABA-A; Reference Values; Stress, Psychological | 2002 |
Imaging the GABA-benzodiazepine receptor subtype containing the alpha5-subunit in vivo with [11C]Ro15 4513 positron emission tomography.
Topics: Animals; Azides; Benzodiazepines; Binding, Competitive; Carbon Radioisotopes; Cerebellum; Cerebral Cortex; Flumazenil; Hippocampus; Humans; Kinetics; Male; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Tissue Distribution; Tomography, Emission-Computed | 2002 |
Quantitative analysis of benzodiazepine receptor in temporal lobe epilepsy: [(125)I]iomazenil autoradiographic study of surgically resected specimens.
Topics: Adolescent; Adult; Autoradiography; Benzodiazepines; Cell Count; Child; Child, Preschool; Epilepsy, Temporal Lobe; Female; Flumazenil; Hippocampus; Humans; Iodine Radioisotopes; Male; Receptors, GABA-A; Sclerosis; Temporal Lobe; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2002 |
Characteristic brain distribution of 1-(14)C-octanoate in a rat model of focal cerebral ischemia in comparison with those of (123)I-IMP and (123)I-iomazenil.
Topics: Animals; Autoradiography; Brain; Brain Ischemia; Caprylates; Disease Models, Animal; Flumazenil; Iofetamine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2003 |
Characterisation of [123I]iomazenil distribution in a rat model of focal cerebral ischaemia in relation to histopathological findings.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Flumazenil; Iodine Radioisotopes; Male; Metabolic Clearance Rate; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2004 |
Cerebral benzodiazepine receptors in depressed patients measured with [123I]iomazenil SPECT.
Topics: Adult; Binding Sites; Brain; Depressive Disorder, Major; Female; Flumazenil; gamma-Aminobutyric Acid; Humans; Male; Occipital Lobe; Receptors, GABA; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 2003 |
Diminished GABA(A) receptor-binding capacity and a DNA base substitution in a patient with treatment-resistant depression and anxiety.
Topics: Adult; Anxiety Disorders; Binding Sites; Brain Mapping; Cerebral Cortex; Depression; Electroconvulsive Therapy; Etomidate; Exons; Flumazenil; Gene Silencing; Humans; Hypnotics and Sedatives; Iodine Isotopes; Male; Point Mutation; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 2004 |
Benzodiazepine receptor deficiency and tinnitus.
Topics: Adult; Aged; Brain; Female; Flumazenil; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Receptors, GABA-A; Surveys and Questionnaires; Tinnitus; Tomography, Emission-Computed, Single-Photon | 2000 |
125I-iomazenil - benzodiazepine receptor binding and serum corticosterone level during psychological stress in a rat model.
Topics: Animals; Brain; Corticosterone; Flumazenil; Male; Protein Binding; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Wistar; Receptors, GABA-A; Severity of Illness Index; Statistics as Topic; Stress, Psychological; Tissue Distribution | 2004 |
Benzodiazepine receptor distribution in severe intractable tinnitus.
Topics: Adult; Aged; Brain; Brain Mapping; Case-Control Studies; Female; Flumazenil; Humans; Image Processing, Computer-Assisted; Iodine Radioisotopes; Male; Middle Aged; Receptors, GABA-A; Tinnitus; Tomography, Emission-Computed, Single-Photon | 2004 |
Correct localization of epileptogenic focus with I-123 iomazenil cerebral benzodiazepine receptor imaging: a case report of temporal lobe epilepsy with discordant ictal cerebral blood flow SPECT.
Topics: Adult; Brain Mapping; Cerebrovascular Circulation; Epilepsy, Temporal Lobe; Female; Flumazenil; Humans; Radiopharmaceuticals; Receptors, GABA-A; Temporal Lobe; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2004 |
Benzodiazepine effect of (125)I-iomazenil-benzodiazepine receptor binding and serum corticosterone level in a rat model.
Topics: Animals; Brain; Corticosterone; Diazepam; Disease Models, Animal; Flumazenil; Male; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Wistar; Receptors, GABA-A; Statistics as Topic; Stress, Psychological; Tissue Distribution | 2005 |
Central-type benzodiazepine receptors and epileptogenesis: basic mechanisms and clinical validity.
Topics: Adult; Amygdala; Animals; Autoradiography; Cerebral Cortex; Dentate Gyrus; Disease Models, Animal; Epilepsies, Partial; Epilepsy, Temporal Lobe; Female; Flumazenil; Hippocampus; Humans; Iodine Radioisotopes; Kainic Acid; Kindling, Neurologic; Magnetic Resonance Imaging; Male; Neocortex; Rats; Receptors, GABA-A; Regional Blood Flow; Tomography, Emission-Computed, Single-Photon | 2005 |
Cortical gamma-aminobutyric acid type A-benzodiazepine receptors in recovery from alcohol dependence: relationship to features of alcohol dependence and cigarette smoking.
Topics: Adult; Alcoholism; Cerebral Cortex; Comorbidity; Ethanol; Flumazenil; Humans; Iodine Radioisotopes; Male; Receptors, GABA-A; Smoking; Substance Withdrawal Syndrome; Temperance; Tomography, Emission-Computed, Single-Photon | 2005 |
SPECT quantification of benzodiazepine receptor concentration using a dual-ligand approach.
Topics: Adult; Female; Flumazenil; Humans; Image Processing, Computer-Assisted; Ligands; Magnetic Resonance Imaging; Male; Middle Aged; Models, Theoretical; Positron-Emission Tomography; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 2006 |
Focal cortical dysplasia: pathophysiological approach.
Topics: Adolescent; Animals; Animals, Newborn; Autoradiography; Behavior, Animal; Brain Diseases; Brain Mapping; Cerebral Cortex; Child; Electroencephalography; Epilepsy; Female; Flumazenil; gamma-Aminobutyric Acid; Humans; Immunohistochemistry; Iodine Radioisotopes; Kainic Acid; Male; Nervous System Malformations; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2006 |
[Influence of benzodiazepines on 123I iomazenil SPECT].
Topics: Adolescent; Benzodiazepines; Child; Child, Preschool; Epilepsy; Female; Flumazenil; Humans; Infant; Male; Tomography, Emission-Computed, Single-Photon | 2006 |
Iomazenil-single-photon emission computed tomography reveals selective neuronal loss in magnetic resonance-defined mismatch areas.
Topics: Adult; Aged; Cell Count; Cerebral Infarction; Female; Flumazenil; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neurons; Stroke; Tomography, Emission-Computed, Single-Photon | 2006 |
Effects of diazepam on 125I-iomazenil-benzodiazepine receptor binding and epileptic seizures in the El mouse.
Topics: Animals; Anticonvulsants; Autoradiography; Brain; Diazepam; Disease Models, Animal; Epilepsy; Flumazenil; Iodine Radioisotopes; Mice; Protein Binding; Receptors, GABA-A; Seizures; Time Factors | 2006 |
Usefulness of 123I-iomazenil single-photon emission computed tomography in discriminating between mesial and lateral temporal lobe epilepsy in patients in whom magnetic resonance imaging demonstrates normal findings.
Topics: Adult; Electroencephalography; Epilepsy, Temporal Lobe; Female; Flumazenil; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; Male; Middle Aged; Predictive Value of Tests; Retrospective Studies; Tomography, Emission-Computed, Single-Photon | 2007 |
Alternative psychosis and dysgraphia accompanied by forced normalization in a girl with occipital lobe epilepsy.
Topics: Agraphia; Anticonvulsants; Carbamazepine; Child; Electroencephalography; Epilepsies, Partial; Female; Flumazenil; Humans; Psychotic Disorders; Tomography, Emission-Computed, Single-Photon | 2008 |
[123I iomazenil SPECT and identification of the epileptogenic tubers in patients with tuberous sclerosis].
Topics: Adolescent; Adult; Cerebral Cortex; Child; Child, Preschool; Epilepsies, Partial; Female; Flumazenil; Humans; Infant; Male; Tomography, Emission-Computed, Single-Photon; Tuberous Sclerosis | 2008 |
MRI-based correction for partial-volume effect improves detectability of intractable epileptogenic foci on 123I-iomazenil brain SPECT images.
Topics: Adult; Artifacts; Brain; Epilepsy; Female; Flumazenil; Humans; Image Enhancement; Imaging, Three-Dimensional; Iodine Radioisotopes; Magnetic Resonance Imaging; Male; Reproducibility of Results; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon | 2008 |
Short-term plasticity of central benzodiazepine receptors in status epilepticus: case report.
Topics: Aged; Biomarkers; Brain; Brain Mapping; Down-Regulation; Female; Flumazenil; gamma-Aminobutyric Acid; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; Neural Inhibition; Neuronal Plasticity; Predictive Value of Tests; Receptors, GABA-A; Status Epilepticus; Synaptic Transmission; Time Factors; Tomography, Emission-Computed, Single-Photon | 2008 |
Postoperative cortical neural loss associated with cerebral hyperperfusion and cognitive impairment after carotid endarterectomy: 123I-iomazenil SPECT study.
Topics: Adult; Aged; Analysis of Variance; Carotid Stenosis; Cerebral Cortex; Cerebrovascular Circulation; Cerebrovascular Disorders; Cognition Disorders; Endarterectomy, Carotid; Female; Flumazenil; Humans; Iofetamine; Male; Middle Aged; Neurons; Neuropsychological Tests; Postoperative Complications; Radiopharmaceuticals; Stereotaxic Techniques; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed | 2009 |
The plasma-occupancy relationship of the novel GABAA receptor benzodiazepine site ligand, alpha5IA, is similar in rats and primates.
Topics: Administration, Oral; Animals; Benzodiazepines; Binding Sites; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Flumazenil; GABA-A Receptor Antagonists; Infusions, Intravenous; Injections, Intravenous; Iodine Radioisotopes; Ligands; Macaca mulatta; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 2009 |
GABAA-benzodiazepine receptor availability in smokers and nonsmokers: relationship to subsyndromal anxiety and depression.
Topics: Adult; Anxiety; Brain; Brain Mapping; Depression; Female; Flumazenil; Humans; Magnetic Resonance Imaging; Male; Pain; Pain Measurement; Psychiatric Status Rating Scales; Receptors, GABA-A; Smoking; Surveys and Questionnaires; Tomography, Emission-Computed, Single-Photon | 2009 |
Interesting image. I-123 iomazenil SPECT imaging in a patient with hemispheric brain damage due to cerebral ischemia during carotid endarterectomy.
Topics: Brain Damage, Chronic; Brain Ischemia; Endarterectomy, Carotid; Flumazenil; Humans; Male; Middle Aged; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon | 2010 |
Spontaneous recovery of reduced cortical central benzodiazepine receptor binding potential on I-123 Iomazenil SPECT in a patient with status epilepticus.
Topics: Adult; Cerebral Cortex; Female; Flumazenil; Humans; Receptors, GABA-A; Remission, Spontaneous; Status Epilepticus; Tomography, Emission-Computed, Single-Photon | 2010 |
Postcarotid endarterectomy improvement in cognition is associated with resolution of crossed cerebellar hypoperfusion and increase in 123I-iomazenil uptake in the cerebral cortex: a SPECT study.
Topics: Adult; Afferent Pathways; Aged; Carotid Artery, Internal; Carotid Stenosis; Cerebellum; Cerebral Cortex; Cognition Disorders; Dominance, Cerebral; Down-Regulation; Endarterectomy, Carotid; Female; Flumazenil; Humans; Iodine Radioisotopes; Ischemia; Male; Middle Aged; Neuropsychological Tests; Receptors, GABA-A; ROC Curve; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2010 |
Epileptic negative myoclonus: a combined study of EEG and [123I]iomazenil (123I-IMZ) single photon emission computed tomography indicating involvement of medial frontal area.
Topics: Electroencephalography; Epilepsies, Myoclonic; Flumazenil; Frontal Lobe; Humans; Iodine Radioisotopes; Male; Reaction Time; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon; Young Adult | 2010 |
SPECT imaging of GABA(A)/benzodiazepine receptors and cerebral perfusion in mild cognitive impairment.
Topics: Aged; Alzheimer Disease; Case-Control Studies; Cerebrovascular Circulation; Cognition Disorders; Female; Flumazenil; Humans; Male; Middle Aged; Receptors, GABA-A; Synapses; Tomography, Emission-Computed, Single-Photon | 2010 |
Defective cerebral gamma-aminobutyric acid-A receptor density in patients with systemic lupus erythematosus and central nervous system involvement. An observational study.
Topics: Adult; Central Nervous System; Cerebral Cortex; Cerebrovascular Circulation; Cognition Disorders; Electroencephalography; Female; Flumazenil; Humans; Iodine Radioisotopes; Lupus Erythematosus, Systemic; Magnetic Resonance Imaging; Middle Aged; Pregnancy; Radiopharmaceuticals; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 2010 |
A case of frontal lobe epilepsy in which amplitude-integrated EEG combined with conventional EEG was useful for evaluating clusters of seizures.
Topics: Child; Cluster Analysis; Electroencephalography; Epilepsy, Frontal Lobe; Flumazenil; Humans; Iodine Isotopes; Magnetic Resonance Imaging; Male; Seizures; Tomography, Emission-Computed, Single-Photon | 2010 |
Recovered neuronal viability revealed by Iodine-123-iomazenil SPECT following traumatic brain injury.
Topics: Adult; Aged; Brain; Brain Injuries; Cell Survival; Female; Flumazenil; Humans; Iodine Radioisotopes; Male; Middle Aged; Neurons; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 2010 |
Reversible dysfunction of receptors in traumatic brain injury?
Topics: Brain Injuries; Flumazenil; Humans; Iodine Radioisotopes; Neurons; Receptors, GABA-A | 2010 |
Central benzodiazepine receptor binding potential and CBF images on SPECT correlate with oxygen extraction fraction images on PET in the cerebral cortex with unilateral major cerebral artery occlusive disease.
Topics: Adult; Aged; Arterial Occlusive Diseases; Basal Ganglia; Carotid Stenosis; Cerebellum; Cerebral Cortex; Cerebrovascular Circulation; Female; Flumazenil; Humans; Image Processing, Computer-Assisted; Infarction, Middle Cerebral Artery; Intracranial Arterial Diseases; Iofetamine; Magnetic Resonance Imaging; Male; Middle Aged; Oxygen Consumption; Oxygen Radioisotopes; Positron-Emission Tomography; Radiopharmaceuticals; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 2011 |
Postoperative resolution of 123I-iomazenil uptake and metabolic rate of oxygen in the cerebral cortex accompanied by postoperative improvement of cognition in a patient undergoing extracranial-intracranial arterial bypass surgery for internal carotid arte
Topics: Biological Transport; Carotid Stenosis; Cerebral Cortex; Cerebral Revascularization; Cognition; Flumazenil; Humans; Male; Middle Aged; Oxygen; Tomography, Emission-Computed, Single-Photon | 2011 |
Iomazenil hyperfixation in single photon emission computed tomography study of malformations of cortical development during infancy.
Topics: Cerebral Cortex; Child, Preschool; Epilepsy; Flumazenil; Humans; Infant; Iodine Radioisotopes; Male; Nervous System Malformations; Tomography, Emission-Computed, Single-Photon | 2011 |
Decreased benzodiazepine receptor and increased GABA level in cortical tubers in tuberous sclerosis complex.
Topics: Aspartic Acid; Brain; Case-Control Studies; Child; Child, Preschool; Female; Flumazenil; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Inositol; Iodine Radioisotopes; Magnetic Resonance Spectroscopy; Male; Protons; Radiopharmaceuticals; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon; Tuberous Sclerosis | 2012 |
Comparison of early and late images on 123I-iomazenil SPECT with cerebral blood flow and oxygen extraction fraction images on PET in the cerebral cortex of patients with chronic unilateral major cerebral artery occlusive disease.
Topics: Adult; Aged; Arterial Occlusive Diseases; Carotid Artery, Internal; Cerebral Arterial Diseases; Cerebral Cortex; Cerebrovascular Circulation; Female; Flumazenil; Humans; Male; Middle Aged; Middle Cerebral Artery; Positron-Emission Tomography; Tomography, Emission-Computed, Single-Photon | 2012 |
Evaluation of the GABAergic nervous system in autistic brain: (123)I-iomazenil SPECT study.
Topics: Adolescent; Brain; Child; Child Development Disorders, Pervasive; Child, Preschool; Flumazenil; gamma-Aminobutyric Acid; Humans; Iodine Radioisotopes; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon | 2012 |
Neuroradiological and neurofunctional examinations for patients with 22q11.2 deletion.
Topics: Case-Control Studies; Child; Child, Preschool; DiGeorge Syndrome; Electroencephalography; Epilepsy; Female; Flumazenil; gamma-Aminobutyric Acid; Humans; Hydrogen; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Malformations of Cortical Development; Radiography; Tomography, Emission-Computed, Single-Photon | 2011 |
Accuracy of central benzodiazepine receptor binding potential/cerebral blood flow SPECT imaging for detecting misery perfusion in patients with unilateral major cerebral artery occlusive diseases: comparison with cerebrovascular reactivity to acetazolamid
Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Area Under Curve; Arterial Occlusive Diseases; Carbonic Anhydrase Inhibitors; Cerebral Angiography; Cerebral Arterial Diseases; Cerebrovascular Circulation; Female; Flumazenil; Humans; Iofetamine; Magnetic Resonance Imaging; Male; Middle Aged; Oxygen Radioisotopes; Positron-Emission Tomography; Predictive Value of Tests; Radiopharmaceuticals; Receptors, GABA-A; ROC Curve; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon | 2012 |
Sex-specific differences in GABA(A) -benzodiazepine receptor availability: relationship with sensitivity to pain and tobacco smoking craving.
Topics: Adult; Affective Symptoms; Analysis of Variance; Animals; Brain; Female; Flumazenil; GABA Modulators; Humans; Male; Middle Aged; Nicotine; Pain Perception; Receptors, GABA-A; Sex Characteristics; Smoking Cessation; Substance Withdrawal Syndrome; Tobacco Use Disorder; Tomography, Emission-Computed, Single-Photon; Young Adult | 2013 |
Distribution of cortical benzodiazepine receptor binding in right-handed healthy humans: a voxel-based statistical analysis of iodine 123 iomazenil SPECT with partial volume correction.
Topics: Adult; Aged; Aged, 80 and over; Aging; Brain; Female; Flumazenil; Functional Laterality; Humans; Image Processing, Computer-Assisted; Iodine Radioisotopes; Magnetic Resonance Imaging; Male; Middle Aged; Radiopharmaceuticals; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 2012 |
Experience of (123)I-iomazenil SPECT study for crossed cerebellocerebral diaschisis: report of two cases.
Topics: Aged; Cerebellar Ataxia; Cerebellar Diseases; Cerebral Angiography; Flumazenil; Headache; Humans; Magnetic Resonance Imaging; Male; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed | 2012 |
MR imaging-based correction for partial volume effect improves detectability of intractable epileptogenic foci on iodine 123 iomazenil brain SPECT images: an extended study with a larger sample size.
Topics: Adult; Algorithms; Artifacts; Brain; Epilepsy; False Negative Reactions; Female; Flumazenil; Humans; Image Enhancement; Magnetic Resonance Imaging; Male; Radiopharmaceuticals; Reproducibility of Results; Sample Size; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon | 2012 |
Altered extrafocal iomazenil activity in mesial temporal lobe epilepsy.
Topics: Adult; Epilepsy, Temporal Lobe; Female; Flumazenil; Follow-Up Studies; Functional Laterality; Humans; Iodine Radioisotopes; Male; Tomography, Emission-Computed, Single-Photon; Young Adult | 2013 |
Regional differences in cortical benzodiazepine receptors of Alzheimer, vascular, and mixed dementia patients.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Brain Mapping; Cerebral Cortex; Cerebrovascular Circulation; Dementia, Vascular; Female; Flumazenil; Frontal Lobe; Humans; Imaging, Three-Dimensional; Iodine Radioisotopes; Iofetamine; Male; Nerve Tissue Proteins; Organ Specificity; Parietal Lobe; Radiography; Radiopharmaceuticals; Receptors, GABA-A; Temporal Lobe; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2012 |
Cortical damage following traumatic brain injury evaluated by iomazenil SPECT and in vivo microdialysis.
Topics: Brain Injuries; Cerebral Cortex; Female; Flumazenil; Humans; Middle Aged; Time Factors; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed | 2013 |
Cortical neuron loss in post-traumatic higher brain dysfunction using (123)I-iomazenil SPECT.
Topics: Adult; Aged; Brain; Brain Injuries; Brain Mapping; Cell Death; Female; Flumazenil; Humans; Male; Middle Aged; Neurons; Tomography, Emission-Computed, Single-Photon | 2013 |
Evaluation of cerebral function using iomazenil SPECT for patients with traumatic brain injury.
Topics: Adolescent; Aged; Brain Injuries; Brain Mapping; Flumazenil; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Tomography, Emission-Computed, Single-Photon | 2013 |
Statistical parametric mapping of interictal 123I-iomazenil SPECT in temporal lobe epilepsy surgery.
Topics: Adolescent; Adult; Brain Mapping; Drug Resistance; Epilepsy, Temporal Lobe; Female; Flumazenil; Functional Laterality; Humans; Image Interpretation, Computer-Assisted; Male; Middle Aged; Neurosurgical Procedures; Radiopharmaceuticals; Retrospective Studies; Seizures; Tomography, Emission-Computed, Single-Photon; Treatment Outcome; Young Adult | 2013 |
123I-iomazenil single photon emission computed tomography visualizes recovery of neuronal integrity by bone marrow stromal cell therapy in rat infarct brain.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Brain Infarction; Flumazenil; Iodine Radioisotopes; Male; Neocortex; Neurons; Radiography; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Recovery of Function; Stromal Cells; Time Factors; Tomography, Emission-Computed, Single-Photon; Transplantation, Homologous | 2013 |
Findings of 123I-iomazenil SPECT during and after stroke-like episodes in a patient with MELAS.
Topics: Adult; Female; Flumazenil; Humans; Iodine Radioisotopes; MELAS Syndrome; Stroke; Tomography, Emission-Computed, Single-Photon | 2014 |
Quantification of GABAA receptors in the rat brain with [(123)I]Iomazenil SPECT from factor analysis-denoised images.
Topics: Animals; Brain; Factor Analysis, Statistical; Flumazenil; Image Processing, Computer-Assisted; Kinetics; Male; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Signal-To-Noise Ratio; Tomography, Emission-Computed, Single-Photon | 2014 |
Cognitive dysfunction might be improved in association with recovered neuronal viability after intracranial meningioma resection.
Topics: Aged; Aged, 80 and over; Brain; Brain Neoplasms; Cell Survival; Cerebrovascular Circulation; Cognition Disorders; Female; Flumazenil; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; Male; Meningioma; Mental Status Schedule; Middle Aged; Neurons; Radiopharmaceuticals; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2014 |
Tobacco smoking interferes with GABAA receptor neuroadaptations during prolonged alcohol withdrawal.
Topics: Analysis of Variance; Animals; Carbon Radioisotopes; Craving; Female; Flumazenil; Humans; Iodine Radioisotopes; Macaca mulatta; Male; Nicotine; Positron-Emission Tomography; Receptors, GABA-A; Smoking; Substance Withdrawal Syndrome; Tomography, Emission-Computed, Single-Photon | 2014 |
A case of succinic semialdehyde dehydrogenase deficiency with status epilepticus and rapid regression.
Topics: Amino Acid Metabolism, Inborn Errors; Atrophy; Brain; Developmental Disabilities; Diffusion Magnetic Resonance Imaging; Disease Progression; Electroencephalography; Flumazenil; Humans; Infant; Male; Radiopharmaceuticals; Status Epilepticus; Succinate-Semialdehyde Dehydrogenase; Tomography, Emission-Computed, Single-Photon | 2016 |
Unique Distribution of Benzodiazepine Receptors in the Brain during the First Two Years of Life.
Topics: Autoradiography; Benzodiazepines; Brain; Child, Preschool; Female; Flumazenil; Frontal Lobe; Humans; Infant; Iodine Radioisotopes; Male; Occipital Lobe; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 2016 |
Abnormal distribution of GABA
Topics: Adolescent; Adult; Age Factors; Brain; Case-Control Studies; Female; Flumazenil; Humans; Male; Muscular Dystrophy, Duchenne; Neuropsychological Tests; Receptors, GABA-A; Retrospective Studies; Tomography, Emission-Computed, Single-Photon; Young Adult | 2017 |
Increase in extraction of I-123 iomazenil in patients with chronic cerebral ischemia.
Topics: Aged; Brain Ischemia; Cerebrovascular Circulation; Chronic Disease; Female; Flumazenil; Humans; Iodine Radioisotopes; Male | 2018 |
Crossed Cerebellar Tracer Uptake on Acute-Stage 123I-Iomazenil SPECT Imaging Predicts 3-Month Functional Outcome in Patients With Nonfatal Hypertensive Putaminal or Thalamic Hemorrhage.
Topics: Aged; Cerebral Hemorrhage; Female; Flumazenil; Humans; Male; Middle Aged; Putamen; Radiopharmaceuticals; Thalamus; Tomography, Emission-Computed, Single-Photon | 2018 |
Maturational Changes of Gamma-Aminobutyric Acid A Receptors Measured With Benzodiazepine Binding of Iodine 123 Iomazenil Single-Photon Emission Computed Tomography.
Topics: Adolescent; Brain; Brain Mapping; Child; Child, Preschool; Epilepsies, Partial; Female; Flumazenil; Humans; Infant; Infant, Newborn; Iodine Radioisotopes; Male; Radiopharmaceuticals; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 2018 |
Double match of
Topics: Adolescent; Adult; Child; Epilepsy; Female; Flumazenil; Fluorodeoxyglucose F18; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neurosurgical Procedures; Positron-Emission Tomography; Postoperative Complications; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon | 2018 |
123I-iomazenil whole-body imaging to detect hepatic carboxylesterase drug-metabolizing enzyme activity.
Topics: Animals; Carboxylesterase; Flumazenil; Liver; Male; Mice; Nitrophenols; Whole Body Imaging | 2018 |
Dynamic image denoising for voxel-wise quantification with Statistical Parametric Mapping in molecular neuroimaging.
Topics: Adult; Algorithms; Flumazenil; Humans; Male; Neuroimaging; Positron Emission Tomography Computed Tomography; Tomography, Emission-Computed, Single-Photon; Young Adult | 2018 |
[
Topics: Aged; Aphasia; Female; Flumazenil; Hematoma, Subdural; Humans; Iodine Radioisotopes; Tomography, Emission-Computed, Single-Photon | 2018 |
Serum Adipokines, Growth Factors, and Cytokines Are Independently Associated with Stunting in Bangladeshi Children.
Topics: Adipokines; Bangladesh; Biomarkers; Body Mass Index; Cytokines; Dietary Supplements; Feces; Female; Flumazenil; Growth Disorders; Growth Substances; Humans; Infant; Male; Poverty Areas; Psychology | 2019 |
Iodine-123-Iomazenil SPECT Revealed Recovery of Neuronal Viability in Association with Improvement in Symptoms Following Treatment for Obstructive Hydrocephalus due to a Giant Posterior Cerebral Artery Aneurysm.
Topics: Aged; Cell Survival; Cerebrovascular Circulation; Cognitive Dysfunction; Female; Flumazenil; Frontal Lobe; Gait Disorders, Neurologic; Humans; Hydrocephalus; Intracranial Aneurysm; Magnetic Resonance Imaging; Neurons; Thrombosis; Tomography, Emission-Computed, Single-Photon; Urinary Incontinence | 2020 |
Detection of Transient Increase of Cerebral Blood Flow and Reversible Neuronal Dysfunction by Iodine-123-Iomazenil Single Photon Emission Computed Tomography After Cerebral Hyperperfusion Syndrome After Revascularization Surgery for Moyamoya Disease.
Topics: Anastomosis, Surgical; Brain; Cerebral Angiography; Cerebral Revascularization; Cerebrovascular Circulation; Female; Flumazenil; Humans; Magnetic Resonance Imaging; Middle Aged; Moyamoya Disease | 2020 |
Long-Term Outcomes of Cerebral Blood Flow and Neurotransmitter Receptor Function on Iodine-123-Iomazenil Single-Photon Emission Computed Tomography and Cognitive Assessments After Parent Artery Occlusion Combined with Cerebral Revascularization for Intern
Topics: Aged; Aged, 80 and over; Brain; Carotid Artery Diseases; Carotid Artery, Internal; Cerebral Revascularization; Cerebrovascular Circulation; Cognition; Female; Flumazenil; Humans; Intracranial Aneurysm; Longitudinal Studies; Middle Aged; Middle Cerebral Artery; Prospective Studies; Receptors, GABA-A; Saphenous Vein; Temporal Arteries; Tomography, Emission-Computed, Single-Photon; Treatment Outcome; Vascular Grafting | 2020 |
Improvement in gait function after carotid endarterectomy is associated with postoperative recovery in perfusion and neurotransmitter receptor function in the motor-related cerebral cortex: a 123I-iomazenil SPECT study.
Topics: Aged; Cerebral Cortex; Cerebrovascular Circulation; Endarterectomy, Carotid; Female; Flumazenil; Gait; Humans; Male; Middle Aged; Motor Activity; Postoperative Period; Receptors, Neurotransmitter; Recovery of Function; Tomography, Emission-Computed, Single-Photon | 2020 |
[123I]Iomazenil SPECT Detects a Reversible Lesion of the Left Medial Temporal Lobe in a Case of Global Autobiographical Amnesia.
Topics: Amnesia; Female; Flumazenil; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; Middle Aged; Temporal Lobe; Tomography, Emission-Computed, Single-Photon | 2021 |
Predicting the retinal content in omega-3 fatty acids for age-related macular-degeneration.
Topics: Aged; Aged, 80 and over; Case-Control Studies; Cholesterol Esters; Dietary Supplements; Discriminant Analysis; Fatty Acids, Omega-3; Female; Flumazenil; Humans; Macular Degeneration; Male; Middle Aged; Retina; Risk Factors | 2021 |
Recovery of Cortical Neurotransmitter Receptor Function and Its Impact on Cognitive Improvement after Indirect Revascularization Surgery Alone for Adult Patients with Ischemic Moyamoya Disease:
Topics: Adult; Cerebral Cortex; Cerebral Revascularization; Cerebrovascular Circulation; Cognition; Flumazenil; Humans; Iodine Radioisotopes; Ischemia; Moyamoya Disease; Prospective Studies; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 2022 |
Late relapse of anti-N-methyl-d-aspartate receptor encephalitis with amusia and transiently reduced uptake in
Topics: Adolescent; Adult; Anti-N-Methyl-D-Aspartate Receptor Encephalitis; Female; Flumazenil; Humans; Iodine Radioisotopes; Neoplasm Recurrence, Local; Receptors, N-Methyl-D-Aspartate; Seizures; Tomography, Emission-Computed, Single-Photon; Young Adult | 2022 |