flumazenil and ro 15-4513

flumazenil has been researched along with ro 15-4513 in 93 studies

Research

Studies (93)

Timeframe	Studies, this research(%)	All Research%
pre-1990	17 (18.28)	18.7374
1990's	48 (51.61)	18.2507
2000's	23 (24.73)	29.6817
2010's	4 (4.30)	24.3611
2020's	1 (1.08)	2.80

Authors

Authors	Studies
Cook, JM; Harris, B; Liu, R; Skolnick, P; Zhang, P; Zhang, W	1
Lüddens, H; Wieland, HA	1
de Costa, BR; Dominguez, C; Gu, ZQ; Rice, KC; Skolnick, P; Wong, G	1
Ananthan, S; Cook, JM; Gu, ZQ; Hunkeler, W; Koehler, KF; Schönholzer, P; Skolnick, P; Wong, G; Zhang, W	1
Cook, JM; Hu, RJ; Liu, R; Skolnick, P; Zhang, P	1
Bennett, DW; Cook, JM; Gan, T; He, X; Huang, Q; Liu, R; McKernan, R; Zhang, P	1
Cook, JM; Dayer, CA; He, X; Huang, Q; Liu, R; Ma, C; McKernan, R; Wenger, GR; Yu, S	1
Baur, R; Ernst, M; Goeldner, M; Gonthier, A; Sigel, E; Tan, KR	1
Clayton, T; Cook, J; DeLorey, TM; Furtmüller, R; Halliwell, RF; Harris, D; Huck, S; Sahbaie, P; Sieghart, W	1
Czajkowski, C; Hanson, SM; Morlock, EV; Satyshur, KA	1
Colker, RE; Domangue, KR; Hicks, LH; June, HL; June, PL; Lewis, MJ; Perry, LE	1
Gibert-Rahola, J; Maldonado, R; Micó, JA; Valverde, O	1
Jackson, HC; Nutt, DJ	1
Mehta, AK; Mhatre, M; Ticku, MK	2
Inoue, O; Itoh, T; Kobayashi, K; Suhara, T; Suzuki, K; Tateno, Y	1
Forster, MJ; Lal, H; Prather, PL	1
Bosman, DK; Chamuleau, RA; de Haan, JG; Maas, MA; van den Buijs, CA	1
Jones, EA	1
Druml, W; Ferenci, P; Püspök, A; Steindl, P	1
Bottlaender, M; Brouillet, E; Chavoix, C; Dodd, RH; Fournier, D; Hantraye, P; Khalili-Varasteh, M; Mazière, M	1
Inoue, O; Itoh, T; Långström, B; Suhara, T; Tsukada, H; Yamasaki, T; Yonezawa, H	1
Engel, JA; Söderpalm, B	1
Budhram, P; Deacon, RM; Gardner, CR; Thomson, TA	1
Koob, GF; Schreiber, JF; Weinger, MB	1
Wettstein, JG	1
Basile, AS; Gammal, SH; Geller, D; Jones, EA; Skolnick, P	1
Alkana, RL; Finn, DA; Jones, BL; Kobayashi, LS; Syapin, PJ	1
Borden, LA; Gibbs, TT	1
Kulkarni, SK; Ticku, MK	1
Becker, HC	1
Mehta, AK; Ticku, MK	1
Haefely, W	1
Bishop, BE; Laverty, R	1
Becker, HC; Hale, RL	1
Biggio, G; Corda, MG; Giorgi, O; Longoni, B	1
Mhatre, M; Ticku, MK	1
Haraguchi, M; Sadeghi, KG; Samson, HH; Tolliver, GA	1
Lister, RG	1
Biggio, G; Corda, MG; Fernández, A; Giorgi, O	1
Moody, EJ; Skolnick, P	1
Bonetti, EP; Burkard, WP; Gabl, M; Hunkeler, W; Lorez, HP; Martin, JR; Moehler, H; Osterrieder, W; Pieri, L; Polc, P	1
Crawley, JN; Glowa, JR; Paul, SM; Schwartz, RD; Skolnick, P; Suzdak, PD	1
Kameyama, T; Nabeshima, T; Tohyama, K	1
Slangen, JL; Woudenberg, F	1
Hiltunen, AJ; Järbe, TU	1
Iwasaki, T; Nakagawa, Y	1
Pokk, P; Zharkovsky, A	2
Miczek, KA; Tornatzky, W; Weerts, EM	1
Hughes, RW; June, HL; Lewis, MJ; Spurlock, HL	1
June, HL; Lewis, MJ	1
Gardner, CR; Pringle, AK; Walker, RJ	1
Andrews, N; File, SE	1
Hu, XJ; Ticku, MK	1
Langeland, BT; McKinley-McKee, JS	1
Basile, AS; Jones, EA; Skolnich, P; Yurdaydin, C	1
Gillard, NP; McKernan, RM; Quirk, K; Ragan, CI; Whiting, PJ	1
Breese, GR; Criswell, HE	1
Khan, RM; Soliman, MR	1
Karim, KH; Najim, RA	1
Barber, DJ; Cooper, SJ	1
Mehta, AK; Shank, RP	1
Inoue, O; Långström, B; Nakanishi, S; Nishiyama, S; Onoe, H; Tsukada, H; Watanabe, Y	1
France, CP; Gerak, LR	2
Akwa, Y; Britton, KT; Brot, MD; Koob, GF; Purdy, RH	1
Benke, D; Michel, C; Mohler, H	1
Cason, CR; Cheatham, G; Cook, JM; Gan, T; June, HL; Lui, R	1
Boileau, AJ; Czajkowski, C; Kucken, AM; Teissére, JA; Wagner, DA; Ward, PR	1
Atack, JR; Bristow, L; Brown, N; Carling, RW; Castro, JL; Cook, G; Dawson, GR; Farrar, S; Ferris, P; Garrett, L; Howell, O; Macaulay, A; Marshall, G; McKernan, RM; Moore, KW; Myers, J; Ragan, CI; Reynolds, DS; Rosahl, TW; Street, LJ; Sur, C; Wafford, KA; Whiting, PJ	1
Firestone, LL; Homanics, GE; Quinlan, JJ	1
France, CP; Gerak, LR; Lelas, S	1
Bromidge, FA; Casula, MA; Hadingham, KL; Martin, K; Maubach, K; Pillai, GV; Seabrook, GR; Whiting, PJ; Wingrove, PB	1
Paz, L; Peter, Y; Pick, CG; Weizman, R	1
Cook, JM; DeLorey, TM; He, X; Lameh, J; Lin, RC; Loew, GH; McBrady, B	1
Al-Mulla Hummadi, YM; Farjou, IB; Najim, RA	1
Pokk, P; Väli, M	1
Atack, J; Banks, G; Kelly, MD; Maubach, KA; Seabrook, GR; Smith, A; Whiting, PW; Wingrove, P	1
Brooks, DJ; Cunningham, VJ; Feeney, A; Hirani, E; Hume, SP; Lingford-Hughes, A; Nutt, DJ; Osman, S; Pike, VW	1
Gatch, MB; Jung, ME; Lal, H; Wallis, CJ	1
Foster, AC; Grigoriadis, DE; Gross, RS; Petroski, RE; Sullivan, SK; Verge, G	1
Atack, JR; Cook, SM; McKernan, RM; Pym, LJ; Rosahl, T	1
Ahboucha, S; Butterworth, RF; Coyne, L; Halliwell, RF; Hirakawa, R	1
Hirano, S; Kamei, J; Miyata, S	1
Hanchar, HJ; Olsen, RW; Wallner, M	1
France, CP; Gerak, LR; McMahon, LR	1
Grant, KA; Helms, CM; Rogers, LS	1
Hellsten, KS; Hyde, TM; Kleinman, JE; Korpi, ER; Maksimow, A; Särkioja, T; Sinkkonen, ST; Uusi-Oukari, M	1
Abe, K; Hosoi, R; Inoue, O; Momosaki, S	1
Banks, ML; Shelton, KL; Tracy, ME	1
Andersson, M; Bölte, S; Borg, J; Cash, D; Farde, L; Gee, A; Halldin, C; Higgins, K; Horder, J; Howes, OD; Lingford-Hughes, A; Lundberg, J; Mendez, MA; Mick, I; Murphy, DG; Nutt, DJ; Selvaraj, S; Sementa, T; Singh, N; Spain, D; Tangen, Ä; Turkheimer, F; Veronese, M	1
Benkherouf, AY; Kortesniemi, M; Laaksonen, O; Logrén, N; Salo-Ahen, OMH; Soini, SL; Somborac, T; Uusi-Oukari, M; Yang, B	1

Reviews

1 review(s) available for flumazenil and ro 15-4513

Article	Year
Do benzodiazepine ligands contribute to hepatic encephalopathy? Advances in experimental medicine and biology, 1993, Volume: 341 Topics: Animals; Azides; Benzodiazepines; Benzodiazepinones; Disease Models, Animal; Flumazenil; GABA-A Receptor Antagonists; Hepatic Encephalopathy; Humans; Ligands; Receptors, GABA-A	1993

Other Studies

92 other study(ies) available for flumazenil and ro 15-4513

Article	Year
Synthesis of novel imidazobenzodiazepines as probes of the pharmacophore for "diazepam-insensitive" GABAA receptors. Journal of medicinal chemistry, 1995, May-12, Volume: 38, Issue:10 Topics: Affinity Labels; Animals; Azides; Benzodiazepines; Diazepam; Male; Molecular Probes; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Structure-Activity Relationship	1995
Four amino acid exchanges convert a diazepam-insensitive, inverse agonist-preferring GABAA receptor into a diazepam-preferring GABAA receptor. Journal of medicinal chemistry, 1994, Dec-23, Volume: 37, Issue:26 Topics: Amino Acid Sequence; Azides; Base Sequence; Benzodiazepines; Binding Sites; Diazepam; GABA Agonists; Humans; Molecular Sequence Data; Mutation; Receptors, GABA-A; Structure-Activity Relationship	1994
Synthesis and evaluation of imidazo[1,5-a][1,4]benzodiazepine esters with high affinities and selectivities at "diazepam-insensitive" benzodiazepine receptors. Journal of medicinal chemistry, 1993, Apr-16, Volume: 36, Issue:8 Topics: Animals; Benzodiazepines; Binding Sites; Brain; Esters; Imidazoles; Male; Rats; Rats, Sprague-Dawley; Receptors, GABA-A	1993
Synthetic and computer-assisted analysis of the structural requirements for selective, high-affinity ligand binding to diazepam-insensitive benzodiazepine receptors. Journal of medicinal chemistry, 1993, Jun-25, Volume: 36, Issue:13 Topics: Animals; Azepines; Benzodiazepines; Cerebellum; Computer Simulation; Diazepam; In Vitro Techniques; Ligands; Male; Models, Molecular; Molecular Conformation; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Structure-Activity Relationship; X-Ray Diffraction	1993
Synthesis and pharmacological properties of novel 8-substituted imidazobenzodiazepines: high-affinity, selective probes for alpha 5-containing GABAA receptors. Journal of medicinal chemistry, 1996, Apr-26, Volume: 39, Issue:9 Topics: Animals; Benzodiazepines; Cerebellum; Flunitrazepam; Hippocampus; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Molecular Probes; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Structure-Activity Relationship	1996
Predictive models for GABAA/benzodiazepine receptor subtypes: studies of quantitative structure-activity relationships for imidazobenzodiazepines at five recombinant GABAA/benzodiazepine receptor subtypes [alphaxbeta3gamma2 (x = 1-3, 5, and 6)] via compar Journal of medicinal chemistry, 1998, Oct-08, Volume: 41, Issue:21 Topics: Animals; Benzodiazepines; Cell Line; Crystallography, X-Ray; Humans; Ligands; Mice; Models, Molecular; Radioligand Assay; Receptors, GABA-A; Recombinant Proteins; Regression Analysis; Structure-Activity Relationship	1998
Pharmacophore/receptor models for GABA(A)/BzR subtypes (alpha1beta3gamma2, alpha5beta3gamma2, and alpha6beta3gamma2) via a comprehensive ligand-mapping approach. Journal of medicinal chemistry, 2000, Jan-13, Volume: 43, Issue:1 Topics: Animals; Benzodiazepines; Carbolines; Cell Line; Columbidae; Conditioning, Operant; Crystallography, X-Ray; Humans; Indoles; Ligands; Male; Models, Molecular; Pyrimidines; Quinolones; Radioligand Assay; Receptors, GABA-A; Saimiri; Stereoisomerism; Structure-Activity Relationship	2000
Proximity-accelerated chemical coupling reaction in the benzodiazepine-binding site of gamma-aminobutyric acid type A receptors: superposition of different allosteric modulators. The Journal of biological chemistry, 2007, Sep-07, Volume: 282, Issue:36 Topics: Allosteric Regulation; Allosteric Site; Amino Acid Substitution; Benzodiazepines; Central Nervous System Agents; Cysteine; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Humans; Ligands; Models, Molecular; Mutation, Missense; Protein Isoforms; Receptors, GABA-A; Structure-Activity Relationship	2007
Selective influence on contextual memory: physiochemical properties associated with selectivity of benzodiazepine ligands at GABAA receptors containing the alpha5 subunit. Journal of medicinal chemistry, 2008, Jul-10, Volume: 51, Issue:13 Topics: Animals; Behavior, Animal; Benzodiazepines; Chemical Phenomena; Chemistry, Physical; Computer Simulation; Databases, Factual; Electrophysiology; Female; Ligands; Male; Memory; Mice; Models, Molecular; Molecular Structure; Oocytes; Protein Isoforms; Protein Subunits; Quantitative Structure-Activity Relationship; Receptors, GABA-A; Structure-Activity Relationship; Xenopus laevis	2008
Structural requirements for eszopiclone and zolpidem binding to the gamma-aminobutyric acid type-A (GABAA) receptor are different. Journal of medicinal chemistry, 2008, Nov-27, Volume: 51, Issue:22 Topics: Azabicyclo Compounds; Benzodiazepines; Binding Sites; Cell Line; Computer Simulation; Cysteine; DNA Mutational Analysis; Eszopiclone; GABA-A Receptor Agonists; Humans; Hydrogen Bonding; Ligands; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Piperazines; Pyridines; Receptors, GABA-A; Structure-Activity Relationship; Zolpidem	2008
Ethanol self-administration in deprived rats: effects of Ro15-4513 alone, and in combination with flumazenil (Ro15-1788). Alcoholism, clinical and experimental research, 1992, Volume: 16, Issue:1 Topics: Alcohol Drinking; Animals; Azides; Benzodiazepines; Brain; Flumazenil; Male; Motivation; Rats; Rats, Inbred Strains; Receptors, GABA-A; Self Administration; Taste	1992
Changes in benzodiazepine-receptor activity modify morphine withdrawal syndrome in mice. Drug and alcohol dependence, 1992, Volume: 30, Issue:3 Topics: Animals; Azides; Behavior, Animal; Benzodiazepines; Benzodiazepinones; Flumazenil; Flunitrazepam; Male; Mice; Morphine; Receptors, GABA-A; Substance Withdrawal Syndrome	1992
Effects of benzodiazepine receptor inverse agonists on locomotor activity and exploration in mice. European journal of pharmacology, 1992, Oct-20, Volume: 221, Issue:2-3 Topics: Animals; Azepines; Azides; Benzodiazepines; Benzodiazepinones; Exploratory Behavior; Flumazenil; Male; Mice; Motor Activity; Receptors, GABA-A	1992
Modulation of GABAergic transmission by ethanol. Advances in biochemical psychopharmacology, 1992, Volume: 47 Topics: Animals; Anticonvulsants; Azides; Benzodiazepines; Brain Chemistry; Ethanol; Female; Flumazenil; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Ion Channels; Male; Mice; Mice, Inbred C57BL; Pentylenetetrazole; Rats; Rats, Inbred Strains; RNA, Messenger; Seizures; Synaptic Transmission	1992
In vivo binding of [11C]Ro15-4513 in human brain measured with PET. Neuroscience letters, 1992, Oct-12, Volume: 145, Issue:2 Topics: Adult; Azides; Benzodiazepines; Brain; Flumazenil; Humans; Ligands; Male; Tomography, Emission-Computed	1992
Learning and memory-enhancing effects of Ro 15-4513: a comparison with flumazenil. Neuropharmacology, 1992, Volume: 31, Issue:3 Topics: Amnesia; Animals; Avoidance Learning; Azides; Benzodiazepines; Discrimination Learning; Flumazenil; Learning; Memory; Mice; Mice, Inbred ICR; Scopolamine; Stimulation, Chemical	1992
The effects of benzodiazepine-receptor antagonists and partial inverse agonists on acute hepatic encephalopathy in the rat. Gastroenterology, 1991, Volume: 101, Issue:3 Topics: Animals; Azides; Benzodiazepines; Benzodiazepinones; Electroencephalography; Evoked Potentials, Visual; Flumazenil; Hepatic Encephalopathy; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A	1991
Benzodiazepine receptor ligands and hepatic encephalopathy: further unfolding of the GABA story. Hepatology (Baltimore, Md.), 1991, Volume: 14, Issue:6 Topics: Animals; Azides; Benzodiazepines; Benzodiazepinones; Brain; Central Nervous System; Flumazenil; gamma-Aminobutyric Acid; Hepatic Encephalopathy; Humans; Ligands; Neurons; Receptors, GABA-A; Synaptic Transmission	1991
Beneficial effect of pharmacological modulation of the GABAA-benzodiazepine receptor on hepatic encephalopathy in the rat: comparison with uremic encephalopathy. Hepatology (Baltimore, Md.), 1991, Volume: 14, Issue:6 Topics: Animals; Azides; Behavior, Animal; Benzodiazepines; Benzodiazepinones; Coma; Flumazenil; Hepatic Encephalopathy; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, GABA-A; Uremia	1991
In vivo bidirectional modulatory effect of benzodiazepine receptor ligands on GABAergic transmission evaluated by positron emission tomography in non-human primates. Brain research, 1991, Aug-23, Volume: 557, Issue:1-2 Topics: Animals; Azides; Benzodiazepines; Benzodiazepinones; Binding, Competitive; Carbolines; Cerebral Cortex; Diazepam; Electroencephalography; Flumazenil; gamma-Aminobutyric Acid; Ligands; Male; Papio; Pentylenetetrazole; Receptors, GABA-A; Seizures; Synaptic Transmission; Tomography, Emission-Computed	1991
Differences of distribution between RO 15-1788 and RO 15-4513 in vivo. Acta radiologica. Supplementum, 1991, Volume: 376 Topics: Animals; Azides; Benzodiazepines; Brain; Flumazenil; Male; Mice	1991
Involvement of the GABAA/benzodiazepine chloride ionophore receptor complex in the 5,7-DHT Induced anticonflict effect. Life sciences, 1991, Volume: 49, Issue:2 Topics: 5,7-Dihydroxytryptamine; Animals; Anti-Anxiety Agents; Azides; Benzodiazepines; Bicuculline; Diazepam; Drinking Behavior; Electroshock; Flumazenil; Hippocampus; Injections, Intraventricular; Limbic System; Male; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin	1991
Differential interactions of Ro 15-4513 with benzodiazepines, ethanol and pentobarbital. European journal of pharmacology, 1990, May-16, Volume: 180, Issue:2-3 Topics: Anesthesia; Animals; Anti-Anxiety Agents; Azides; Behavior, Animal; Benzodiazepines; Diazepam; Drug Interactions; Ethanol; Female; Flumazenil; Male; Muscle Contraction; Muscles; Pentobarbital; Rats; Rats, Inbred Strains; Urethane; Vocalization, Animal	1990
Effects of two benzodiazepine inverse agonists, RO 15-4513 and FG 7142, on recovery from pentobarbital and halothane anesthesia in the rat. Pharmacology, biochemistry, and behavior, 1990, Volume: 35, Issue:4 Topics: Anesthesia Recovery Period; Animals; Azides; Benzodiazepines; Carbolines; Flumazenil; Halothane; Male; Pentobarbital; Random Allocation; Rats; Rats, Inbred Strains; Reflex	1990
Unusual behavioral profile of alprazolam in squirrel monkeys. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:3 Topics: Alprazolam; Animals; Azides; Benzodiazepines; Dose-Response Relationship, Drug; Electroshock; Flumazenil; Injections, Intravenous; Lorazepam; Male; Psychomotor Performance; Saimiri	1990
Reversal of the behavioral and electrophysiological abnormalities of an animal model of hepatic encephalopathy by benzodiazepine receptor ligands. Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:3 Topics: Animals; Azides; Benzodiazepines; Disease Models, Animal; Electrophysiology; Evoked Potentials, Visual; Flumazenil; Hepatic Encephalopathy; Ligands; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, GABA-A	1990
Interactions between benzodiazepine antagonists, inverse agonists, and acute behavioral effects of ethanol in mice. Brain research bulletin, 1990, Volume: 24, Issue:5 Topics: Animals; Azides; Benzodiazepines; Dose-Response Relationship, Drug; Ethanol; Flumazenil; GABA-A Receptor Antagonists; Hypothermia; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Receptors, GABA-A; Reflex	1990
Flunitrazepam photoaffinity labeling of the GABA(A) receptor reduces inhibition of [3H]Ro15-4513 binding by GABA. European journal of pharmacology, 1990, Jun-12, Volume: 188, Issue:6 Topics: Affinity Labels; Animals; Azides; Benzodiazepines; Brain; Chick Embryo; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Membranes; Photochemistry; Receptors, GABA-A	1990
Chronic benzodiazepine antagonist treatment and its withdrawal upregulates components of GABA-benzodiazepine receptor ionophore complex in cerebral cortex of rat. Brain research, 1990, Jun-11, Volume: 519, Issue:1-2 Topics: Affinity Labels; Animals; Azides; Benzodiazepines; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Convulsants; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, GABA-A; Reference Values; Up-Regulation	1990
Effects of the imidazobenzodiazepine RO15-4513 on the stimulant and depressant actions of ethanol on spontaneous locomotor activity. Life sciences, 1988, Volume: 43, Issue:7 Topics: Animals; Azides; Benzodiazepines; Carbolines; Chlorides; Ethanol; Flumazenil; Ion Channels; Male; Mice; Mice, Inbred C3H; Motor Activity; Receptors, GABA-A	1988
Ethanol potentiation of GABAergic transmission in cultured spinal cord neurons involves gamma-aminobutyric acidA-gated chloride channels. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:2 Topics: Animals; Azides; Benzodiazepines; Carbolines; Cells, Cultured; Chlorine; Ethanol; Female; Flumazenil; GABA Antagonists; gamma-Aminobutyric Acid; Ion Channels; Male; Mice; Mice, Inbred C57BL; Neurons; Radioisotopes; Spinal Cord	1988
Partial agonists of the benzodiazepine receptor: from animal data to results in patients. Advances in biochemical psychopharmacology, 1988, Volume: 45 Topics: Affinity Labels; Allosteric Site; Animals; Azides; Benzodiazepines; Benzodiazepinones; Chlordiazepoxide; Chlorides; Clonazepam; Diazepam; Drug Interactions; Ethanol; Flumazenil; Flurazepam; Humans; Ion Channels; Ligands; Models, Neurological; Neurons; Receptors, GABA-A	1988
Dose-dependent reduction by Ro 15-4513 in mice of the effects of ethanol and some other general depressant drugs. European journal of pharmacology, 1989, Mar-21, Volume: 162, Issue:2 Topics: Anesthetics; Animals; Azides; Benzodiazepines; Central Nervous System Depressants; Dose-Response Relationship, Drug; Ethanol; Flumazenil; Mice; Sleep; Time Factors	1989
Ethanol-induced locomotor stimulation in C57BL/6 mice following RO15-4513 administration. Psychopharmacology, 1989, Volume: 99, Issue:3 Topics: Animals; Azides; Benzodiazepines; Carbolines; Ethanol; Flumazenil; Male; Mice; Mice, Inbred C57BL; Motor Activity	1989
Ro 15-4513, a partial inverse agonist for benzodiazepine recognition sites, has proconflict and proconvulsant effects in the rat. European journal of pharmacology, 1989, Jan-17, Volume: 159, Issue:3 Topics: Animals; Azides; Benzodiazepines; Carbolines; Conflict, Psychological; Convulsants; Flumazenil; Isoniazid; Male; Pentobarbital; Punishment; Rats; Rats, Inbred Strains; Receptors, GABA-A	1989
Chronic ethanol treatment selectively increases the binding of inverse agonists for benzodiazepine binding sites in cultured spinal cord neurons. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:1 Topics: Alcoholism; Animals; Azides; Benzodiazepines; Cells, Cultured; Female; Flumazenil; Flunitrazepam; Male; Mice; Mice, Inbred C57BL; Neurons; Receptors, GABA-A; Spinal Cord	1989
Antagonism of ethanol-reinforced behavior by the benzodiazepine inverse agonists Ro15-4513 and FG 7142: relation to sucrose reinforcement. Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:3 Topics: Animals; Azides; Behavior, Animal; Benzodiazepines; Carbolines; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Flumazenil; Male; Rats; Receptors, GABA-A; Reinforcement, Psychology; Self Administration; Sucrose	1989
Reversal of the intrinsic effects of Ro 15-4513 on exploratory behavior by two benzodiazepine receptor antagonists. Neuroscience letters, 1987, Aug-31, Volume: 79, Issue:3 Topics: Animals; Azides; Benzodiazepines; Carbolines; Exploratory Behavior; Flumazenil; Male; Mice; Motor Activity; Receptors, GABA-A	1987
The abstinence syndrome in diazepam-dependent cats is precipitated by Ro 15-1788 and Ro 15-4513 but not by the benzodiazepine receptor antagonist ZK 93426. Neuroscience letters, 1988, May-26, Volume: 88, Issue:2 Topics: Animals; Azides; Benzodiazepines; Carbolines; Cats; Diazepam; Flumazenil; Receptors, GABA-A; Substance Withdrawal Syndrome	1988
The imidazobenzodiazepine Ro 15-4513 antagonizes methoxyflurane anesthesia. Life sciences, 1988, Volume: 43, Issue:16 Topics: Anesthesia, General; Animals; Azides; Benzodiazepines; Carbolines; Flumazenil; Male; Methoxyflurane; Mice; Receptors, GABA-A; Sleep	1988
Chronic ethanol administration increases the binding of the benzodiazepine inverse agonist and alcohol antagonist [3H]RO15-4513 in rat brain. European journal of pharmacology, 1988, Aug-09, Volume: 153, Issue:1 Topics: Acoustic Stimulation; Animals; Azides; Benzodiazepines; Body Temperature; Brain Chemistry; Diazepam; Ethanol; Flumazenil; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures	1988
Ro 15-4513: partial inverse agonism at the BZR and interaction with ethanol. Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:3 Topics: Animals; Azides; Behavior, Animal; Benzodiazepines; Brain; Brain Chemistry; Cats; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Ethanol; Flumazenil; Meta-Analysis as Topic; Mice; Phenobarbital; Rats; Receptors, GABA-A	1988
A selective imidazobenzodiazepine antagonist of ethanol in the rat. Science (New York, N.Y.), 1986, Dec-05, Volume: 234, Issue:4781 Topics: Animals; Anxiety; Azides; Benzodiazepines; Chlorides; Ethanol; Flumazenil; Male; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes	1986
Reversal of alcohol-induced amnesia by the benzodiazepine inverse agonist Ro 15-4513. European journal of pharmacology, 1988, Oct-18, Volume: 155, Issue:3 Topics: Amnesia; Animals; Avoidance Learning; Azides; Benzodiazepines; Carbolines; Dose-Response Relationship, Drug; Ethanol; Flumazenil; Male; Mice; Time Factors	1988
Ethanol suppression of schedule-controlled responding: interactions with Ro 15-4513, Ro 15-1788 and CGS 8216. Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:2 Topics: Alcohol Deterrents; Animals; Azides; Behavior, Animal; Benzodiazepines; Drug Interactions; Ethanol; Flumazenil; Male; Pyrazoles; Rats; Rats, Inbred Strains	1988
Effects of Ro 15-4513, alone or in combination with ethanol, Ro 15-1788, diazepam, and pentobarbital on instrumental behaviors of rats. Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:3 Topics: Animals; Azides; Behavior, Animal; Benzodiazepines; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Female; Flumazenil; Pentobarbital; Rats; Rats, Inbred Strains; Time Factors	1988
Involvement of benzodiazepine/GABA-A receptor complex in ethanol-induced state-dependent learning in rats. Brain research, 1995, Jul-17, Volume: 686, Issue:1 Topics: Animals; Avoidance Learning; Azides; Benzodiazepines; Bicuculline; Diazepam; Ethanol; Evaluation Studies as Topic; Flumazenil; Male; Muscimol; Picrotoxin; Rats; Rats, Wistar; Reaction Time; Receptors, GABA-A	1995
The effects of drugs acting at GABA-benzodiazepine-barbiturate receptor complex on the behaviour of sleep-deprived mice. Pharmacology & toxicology, 1995, Volume: 76, Issue:1 Topics: Analysis of Variance; Animals; Azides; Behavior, Animal; Benzodiazepines; Convulsants; Diazepam; Flumazenil; Male; Mice; Receptors, GABA-A; Sleep Deprivation	1995
"Anxiolytic" and "anxiogenic" benzodiazepines and beta-carbolines: effects on aggressive and social behavior in rats and squirrel monkeys. Psychopharmacology, 1993, Volume: 110, Issue:4 Topics: Aggression; Animals; Anti-Anxiety Agents; Anxiety; Azides; Benzodiazepines; Carbolines; Dose-Response Relationship, Drug; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Male; Motor Activity; Rats; Saimiri; Social Behavior; Species Specificity	1993
Ethanol self-administration in freely feeding and drinking rats: effects of Ro15-4513 alone, and in combination with Ro15-1788 (flumazenil). Psychopharmacology, 1994, Volume: 115, Issue:3 Topics: Alcohol Drinking; Animals; Azides; Benzodiazepines; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Flumazenil; GABA-A Receptor Agonists; Male; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology	1994
Interactions of Ro15-4513, Ro15-1788 (flumazenil) and ethanol on measures of exploration and locomotion in rats. Psychopharmacology, 1994, Volume: 116, Issue:3 Topics: Animals; Anti-Anxiety Agents; Azides; Benzodiazepines; Dose-Response Relationship, Drug; Environment; Ethanol; Exploratory Behavior; Flumazenil; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, GABA-A	1994
Different functional effect of Ro 15-4513 and Ro 19-4603 on synaptic responses of Purkinje cells in the rat cerebellar slice. Brain research, 1994, Dec-05, Volume: 665, Issue:2 Topics: Animals; Azepines; Azides; Benzodiazepines; Cerebellum; Diazepam; Electrophysiology; Flumazenil; In Vitro Techniques; Male; Neural Inhibition; Purkinje Cells; Rats; Rats, Wistar; Receptors, GABA-A; Synapses	1994
F 2692: flumazenil-reversible anxiolytic effects but inactive on [3H]-Ro 15-4513 binding. Pharmacology, biochemistry, and behavior, 1994, Volume: 48, Issue:1 Topics: Affinity Labels; Animals; Anti-Anxiety Agents; Azides; Benzodiazepines; Binding, Competitive; Carbolines; Cerebellum; Diazepam; Flumazenil; GABA-A Receptor Antagonists; In Vitro Techniques; Interpersonal Relations; Male; Membranes; Motor Activity; Pyridazines; Rats; Receptors, GABA-A	1994
Development pattern of the GABAA-benzodiazepine receptor ionophore complex in primary cultures of cortical neurons. Brain research. Developmental brain research, 1994, Jul-15, Volume: 80, Issue:1-2 Topics: Affinity Labels; Animals; Azides; Benzodiazepines; Cells, Cultured; Cerebral Cortex; Chlorides; Flumazenil; Flunitrazepam; Mice; Mice, Inbred C57BL; Muscimol; Neurons; Receptors, GABA-A	1994
Inhibition and inactivation of horse liver alcohol dehydrogenase with the imidazobenzodiazepine Ro 15-4513. Archives of biochemistry and biophysics, 1994, Feb-01, Volume: 308, Issue:2 Topics: Affinity Labels; Alcohol Dehydrogenase; Animals; Azides; Benzodiazepines; Flumazenil; Horses; Hydrogen-Ion Concentration; Kinetics; Liver; Mathematics; Molecular Structure; NAD	1994
Model of subunit composition of gamma-aminobutyric acid A receptor subtypes expressed in rat cerebellum with respect to their alpha and gamma/delta subunits. The Journal of biological chemistry, 1994, Jun-10, Volume: 269, Issue:23 Topics: Animals; Azides; Base Sequence; Benzodiazepines; Cerebellum; Escherichia coli; Flumazenil; Molecular Sequence Data; Muscimol; Precipitin Tests; Protein Conformation; Rats; Receptors, GABA-A; Recombinant Proteins	1994
Similar effects of ethanol and flumazenil on acquisition of a shuttle-box avoidance response during withdrawal from chronic ethanol treatment. British journal of pharmacology, 1993, Volume: 110, Issue:2 Topics: Animals; Avoidance Learning; Azides; Benzodiazepines; Chlordiazepoxide; Conflict, Psychological; Dose-Response Relationship, Drug; Ethanol; Flumazenil; Male; Postural Balance; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome	1993
Effects of benzodiazepine agonist, antagonist and inverse agonist on ethanol-induced changes in beta-endorphin levels in specific rat brain regions. Pharmacology, 1993, Volume: 47, Issue:6 Topics: Affinity Labels; Animals; Azides; Benzodiazepines; beta-Endorphin; Brain Chemistry; Cerebral Cortex; Diazepam; Ethanol; Flumazenil; Hippocampus; Hypothalamus; Male; Rats; Rats, Sprague-Dawley	1993
Prevention of ethanol-induced gastric damage by the imidazobenzodiazepines Ro 15-4513 and Ro 15-3505 in rats. Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:3 Topics: Animals; Azides; Benzodiazepines; Benzodiazepinones; Ethanol; Flumazenil; Male; Rats; Rats, Wistar; Stomach Ulcer	1993
The benzodiazepine receptor partial agonist bretazenil and the partial inverse agonist Ro 15-4513: effects on salt preference and aversion in the rat. Brain research, 1993, May-28, Volume: 612, Issue:1-2 Topics: Animals; Azides; Benzodiazepines; Benzodiazepinones; Flumazenil; Food Preferences; Male; Rats; Receptors, GABA-A; Saline Solution, Hypertonic; Sodium Chloride; Taste	1993
Characterization of a benzodiazepine receptor site with exceptionally high affinity for Ro 15-4513 in the rat CNS. Brain research, 1995, Dec-18, Volume: 704, Issue:2 Topics: Affinity Labels; Animals; Anti-Anxiety Agents; Azides; Benzodiazepines; Binding Sites; Binding, Competitive; Central Nervous System; Cerebellum; Chlorides; Dose-Response Relationship, Drug; Flumazenil; Flunitrazepam; GABA Modulators; Hippocampus; Imidazoles; Male; Pyridines; Rats; Rats, Wistar; Receptors, GABA-A; Spinal Cord; Tritium	1995
A subclass of GABAA/benzodiazepine receptor exclusively localized in the limbic system. Neuroreport, 1996, Dec-20, Volume: 8, Issue:1 Topics: Affinity Labels; Animals; Autoradiography; Azides; Benzodiazepines; Carbon Radioisotopes; Female; Flumazenil; GABA Modulators; Image Processing, Computer-Assisted; Isotope Labeling; Limbic System; Macaca mulatta; Receptors, GABA-A; Tomography, Emission-Computed	1996
Discriminative stimulus effects of flumazenil in rhesus monkeys treated chronically with chlordiazepoxide. Pharmacology, biochemistry, and behavior, 1997, Volume: 56, Issue:3 Topics: Animals; Anti-Anxiety Agents; Avoidance Learning; Azides; Benzodiazepines; Chlordiazepoxide; Discrimination Learning; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Antagonists; Macaca mulatta; Pharmaceutical Vehicles; Time Factors	1997
The anxiolytic-like effects of the neurosteroid allopregnanolone: interactions with GABA(A) receptors. European journal of pharmacology, 1997, Apr-23, Volume: 325, Issue:1 Topics: Affinity Labels; Animals; Anti-Anxiety Agents; Anxiety; Azides; Behavior, Animal; Benzodiazepines; Binding Sites; Chloride Channels; Conflict, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Organophosphorus Compounds; Pregnanolone; Rats; Rats, Wistar; Receptors, GABA-A	1997
The effects of flumazenil, Ro 15-4513 and beta-CCM on the behaviour of control and stressed mice in the plus-maze test. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1997, Volume: 48, Issue:2 Topics: Animals; Anxiety; Azides; Behavior, Animal; Benzodiazepines; Carbolines; Dose-Response Relationship, Drug; Flumazenil; GABA Modulators; Ligands; Male; Mice; Stress, Psychological	1997
GABA(A) receptors containing the alpha4-subunit: prevalence, distribution, pharmacology, and subunit architecture in situ. Journal of neurochemistry, 1997, Volume: 69, Issue:2 Topics: Animals; Azides; Benzodiazepines; Benzodiazepinones; Brain; Cell Membrane; Cerebellum; Diazepam; Flumazenil; Immunohistochemistry; Immunosorbent Techniques; Macromolecular Substances; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recombinant Proteins	1997
GABAA-benzodiazepine receptors in the striatum are involved in the sedation produced by a moderate, but not an intoxicating ethanol dose in outbred Wistar rats. Brain research, 1998, May-25, Volume: 794, Issue:1 Topics: Alcoholic Intoxication; Analysis of Variance; Animals; Azides; Benzodiazepines; Corpus Striatum; Ethanol; Flumazenil; GABA Agents; GABA-A Receptor Agonists; Hypnotics and Sedatives; Male; Oocytes; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A; Xenopus	1998
Discriminative stimulus effects of flumazenil in untreated and in diazepam-treated rhesus monkeys. Psychopharmacology, 1999, Volume: 146, Issue:3 Topics: Animals; Azides; Benzodiazepines; Carbolines; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Modulators; Macaca mulatta; Male; Receptors, GABA-A	1999
Identification of benzodiazepine binding site residues in the gamma2 subunit of the gamma-aminobutyric acid(A) receptor. Molecular pharmacology, 2000, Volume: 57, Issue:5 Topics: Amino Acid Sequence; Azides; Benzodiazepines; Binding Sites; Cells, Cultured; Cloning, Molecular; Flumazenil; Flunitrazepam; Humans; Molecular Sequence Data; Point Mutation; Receptors, GABA-A; Recombinant Fusion Proteins; Sequence Homology, Amino Acid	2000
Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype. Nature neuroscience, 2000, Volume: 3, Issue:6 Topics: Allosteric Site; Animals; Anti-Anxiety Agents; Anticonvulsants; Azides; Benzodiazepines; Binding, Competitive; Brain; Cell Line; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Fluorobenzenes; GABA-A Receptor Antagonists; Hypnotics and Sedatives; Ligands; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Motor Activity; Patch-Clamp Techniques; Receptors, GABA-A; Reflex, Startle; Triazoles	2000
Mice lacking the long splice variant of the gamma 2 subunit of the GABA(A) receptor are more sensitive to benzodiazepines. Pharmacology, biochemistry, and behavior, 2000, Volume: 66, Issue:2 Topics: Alternative Splicing; Animals; Azides; Benzodiazepines; Brain; Carbolines; Diazepam; Drug Resistance; Female; Flumazenil; GABA Modulators; Genetic Variation; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Midazolam; Pyridines; Receptors, GABA-A; Sleep; Zolpidem	2000
Antagonism of the discriminative stimulus effects of positive gamma-aminobutyric acid(A) modulators in rhesus monkeys discriminating midazolam. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:3 Topics: Animals; Azides; Benzodiazepines; Carbolines; Diazepam; Discrimination Learning; Drug Antagonism; Female; Flumazenil; GABA Modulators; Macaca mulatta; Male; Midazolam; Receptors, GABA-A	2000
Identification of amino acid residues responsible for the alpha5 subunit binding selectivity of L-655,708, a benzodiazepine binding site ligand at the GABA(A) receptor. Journal of neurochemistry, 2001, Volume: 77, Issue:2 Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Anti-Anxiety Agents; Azides; Benzodiazepines; Binding Sites; Binding, Competitive; Carbolines; DNA, Complementary; Female; Flumazenil; Flunitrazepam; GABA-A Receptor Agonists; Humans; Imidazoles; Isoleucine; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Protein Binding; Protein Structure, Tertiary; Protein Subunits; Pyridazines; Pyridines; Receptors, GABA-A; Recombinant Fusion Proteins; Sequence Alignment; Structure-Activity Relationship; Threonine; Transfection; Xenopus laevis; Zolpidem	2001
Mice performance on the staircase test following acute ethanol administration. Pharmacology, biochemistry, and behavior, 2001, Volume: 68, Issue:3 Topics: Animals; Azides; Benzodiazepines; Central Nervous System Depressants; Diazepam; Dose-Response Relationship, Drug; Ethanol; Flumazenil; GABA Modulators; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred ICR; Psychomotor Performance	2001
Influence of benzodiazepine binding site ligands on fear-conditioned contextual memory. European journal of pharmacology, 2001, Aug-24, Volume: 426, Issue:1-2 Topics: Animals; Azides; Benzodiazepines; Binding Sites; Binding, Competitive; Carbolines; Conditioning, Psychological; Convulsants; Fear; Flumazenil; GABA Antagonists; GABA Modulators; Imidazoles; Ligands; Male; Memory; Mice; Mice, Inbred C57BL; Motor Activity; N-Methylscopolamine; Piperazines; Quinolines; Receptors, GABA-A; Scopolamine; Silanes; Tritium	2001
Benzodiazepines protect against ethanol-induced gastric mucosal damage in vitro. Fundamental & clinical pharmacology, 2001, Volume: 15, Issue:4 Topics: Affinity Labels; Animals; Azides; Benzodiazepines; Central Nervous System Depressants; Clonazepam; Ethanol; Flumazenil; GABA Modulators; Gastric Mucosa; In Vitro Techniques; Male; Rats; Rats, Wistar; Stomach Ulcer	2001
The effects of flumazenil, Ro 154513 and beta-CCM on the behaviour of control and stressed mice in the staircase test. Journal of psychopharmacology (Oxford, England), 2001, Volume: 15, Issue:3 Topics: Animals; Arousal; Azides; Benzodiazepines; Carbolines; Dose-Response Relationship, Drug; Escape Reaction; Exploratory Behavior; Fear; Flumazenil; Immobilization; Male; Mice; Mice, Inbred BALB C; Sleep Deprivation; Sleep, REM; Social Isolation; Stress, Psychological	2001
Role of the histidine residue at position 105 in the human alpha 5 containing GABA(A) receptor on the affinity and efficacy of benzodiazepine site ligands. British journal of pharmacology, 2002, Volume: 135, Issue:1 Topics: Anticonvulsants; Arginine; Azides; Benzodiazepines; Benzodiazepinones; Binding Sites; Binding, Competitive; Cell Line; Cells, Cultured; Flumazenil; GABA Modulators; gamma-Aminobutyric Acid; Histidine; Humans; Ligands; Mutation; Protein Subunits; Receptors, GABA-A	2002
Imaging the GABA-benzodiazepine receptor subtype containing the alpha5-subunit in vivo with [11C]Ro15 4513 positron emission tomography. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2002, Volume: 22, Issue:7 Topics: Animals; Azides; Benzodiazepines; Binding, Competitive; Carbon Radioisotopes; Cerebellum; Cerebral Cortex; Flumazenil; Hippocampus; Humans; Kinetics; Male; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Tissue Distribution; Tomography, Emission-Computed	2002
Effects of GABA(A) compounds on mCPP drug discrimination in rats. Life sciences, 2002, Oct-18, Volume: 71, Issue:22 Topics: Alprazolam; Animals; Azides; Benzodiazepines; Bicuculline; Conditioning, Operant; Discrimination, Psychological; Flumazenil; GABA Agonists; GABA Antagonists; Male; Pentylenetetrazole; Piperazines; Rats; Rats, Long-Evans; Receptors, GABA-A	2002
Characterization of the interaction of indiplon, a novel pyrazolopyrimidine sedative-hypnotic, with the GABAA receptor. The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:2 Topics: Acetamides; Animals; Azides; Benzodiazepines; Binding Sites; Brain; Cell Membrane; Cerebellum; Cerebral Cortex; Chloride Channels; Flumazenil; GABA Modulators; gamma-Aminobutyric Acid; Kinetics; Male; Pyridines; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Thiophenes; Triazolam; Tritium; Zolpidem	2004
Selective labelling of diazepam-insensitive GABAA receptors in vivo using [3H]Ro 15-4513. British journal of pharmacology, 2005, Volume: 146, Issue:6 Topics: Animals; Azides; Benzodiazepines; Benzodiazepinones; Binding, Competitive; Cerebellum; Flumazenil; Humans; Isotope Labeling; Ligands; Lorazepam; Male; Mice; Mice, Transgenic; Prosencephalon; Receptors, GABA-A; Receptors, GABA-B; Tritium	2005
An interaction between benzodiazepines and neuroactive steroids at GABA A receptors in cultured hippocampal neurons. Neurochemistry international, 2006, Volume: 48, Issue:8 Topics: Affinity Labels; Allosteric Regulation; Animals; Azides; Benzodiazepines; Cells, Cultured; Chloride Channels; Dose-Response Relationship, Drug; Drug Interactions; Female; Flumazenil; GABA Modulators; Hepatic Encephalopathy; Hippocampus; Male; Neural Inhibition; Neurons; Patch-Clamp Techniques; Pregnanolone; Rats; Rats, Wistar; Receptors, GABA-A; Synaptic Transmission	2006
Involvement of diazepam-insensitive benzodiazepine receptors in the suppression of DOI-induced head-twitch responses in diabetic mice. Psychopharmacology, 2006, Volume: 186, Issue:1 Topics: Amphetamines; Animals; Azides; Behavior, Animal; Benzodiazepines; Bicuculline; Diabetes Mellitus, Experimental; Diazepam; Flumazenil; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Male; Mice; Mice, Inbred ICR; Receptors, GABA-A; Serotonin Receptor Agonists	2006
Low-dose alcohol actions on alpha4beta3delta GABAA receptors are reversed by the behavioral alcohol antagonist Ro15-4513. Proceedings of the National Academy of Sciences of the United States of America, 2006, May-30, Volume: 103, Issue:22 Topics: Animals; Azides; Benzodiazepines; Carbolines; Electrophysiology; Esters; Ethanol; Flumazenil; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Molecular Structure; Mutation; Oocytes; Patch-Clamp Techniques; Protein Subunits; Receptors, GABA-A; Xenopus laevis	2006
Efficacy and the discriminative stimulus effects of negative GABAA modulators, or inverse agonists, in diazepam-treated rhesus monkeys. The Journal of pharmacology and experimental therapeutics, 2006, Volume: 318, Issue:2 Topics: Animals; Azides; Benzodiazepines; Conditioning, Operant; Cues; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Agonists; GABA Modulators; Hypnotics and Sedatives; Macaca mulatta; Male; Pentobarbital; Pregnanolone; Receptors, GABA-A	2006
Antagonism of the ethanol-like discriminative stimulus effects of ethanol, pentobarbital, and midazolam in cynomolgus monkeys reveals involvement of specific GABA(A) receptor subtypes. The Journal of pharmacology and experimental therapeutics, 2009, Volume: 331, Issue:1 Topics: Animals; Azides; Benzodiazepines; Discrimination Learning; Dose-Response Relationship, Drug; Ethanol; Female; Flumazenil; Macaca fascicularis; Male; Midazolam; Pentobarbital; Protein Subunits; Receptors, GABA-A	2009
Human locus coeruleus neurons express the GABA(A) receptor gamma2 subunit gene and produce benzodiazepine binding. Neuroscience letters, 2010, Jun-21, Volume: 477, Issue:2 Topics: Adult; Autoradiography; Azides; Benzodiazepines; Female; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Humans; Locus Coeruleus; Male; Melanins; Neurons; Pyridines; Radioligand Assay; Receptors, GABA-A; Tyrosine 3-Monooxygenase; Zolpidem	2010
Remarkable selectivity of the in vivo binding of [3H]Ro15-4513 to α5 subtype of benzodiazepine receptor in the living mouse brain. Synapse (New York, N.Y.), 2010, Volume: 64, Issue:12 Topics: Affinity Labels; Animals; Azides; Benzodiazepines; Binding, Competitive; Brain; Carbolines; Dose-Response Relationship, Drug; Flumazenil; Flunitrazepam; Male; Mice; Protein Subunits; Receptors, GABA-A; Tritium	2010
Negative allosteric modulation of GABAA receptors inhibits facilitation of brain stimulation reward by drugs of abuse in C57BL6/J mice. Psychopharmacology, 2016, Volume: 233, Issue:4 Topics: Allosteric Regulation; Animals; Azides; Benzodiazepines; Brain; Diazepam; Dose-Response Relationship, Drug; Flumazenil; GABA Modulators; gamma-Aminobutyric Acid; Illicit Drugs; Male; Mice; Mice, Inbred C57BL; Microdialysis; Receptors, GABA-A; Reward; Self Stimulation	2016
GABA Science translational medicine, 2018, 10-03, Volume: 10, Issue:461 Topics: Adult; Animals; Autism Spectrum Disorder; Azides; Behavior; Benzodiazepines; Carbon Radioisotopes; Case-Control Studies; Disease Models, Animal; Female; Flumazenil; Gray Matter; Humans; Male; Mice; Motion Perception; Positron-Emission Tomography; Protein Subunits; Receptors, GABA-A; Task Performance and Analysis	2018
Hops compounds modulatory effects and 6-prenylnaringenin dual mode of action on GABA European journal of pharmacology, 2020, Apr-15, Volume: 873 Topics: Animals; Azides; Benzodiazepines; Binding, Competitive; Cyclohexenes; Dose-Response Relationship, Drug; Flavonoids; Flumazenil; Flunitrazepam; GABA Modulators; Humulus; Male; Molecular Docking Simulation; Plant Extracts; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Terpenes	2020