flumazenil has been researched along with prazosin in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.56) | 18.7374 |
| 1990's | 3 (16.67) | 18.2507 |
| 2000's | 6 (33.33) | 29.6817 |
| 2010's | 8 (44.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Fujigaki, T; Makita, T; Nakamura, H; Shibata, O; Sumikawa, K; Tsujita, T | 1 |
| Breschi, MC; Cristofani, R; Giannaccini, G; Lucacchini, A; Martini, C; Martinotti, E; Scatizzi, R | 1 |
| Castro, JL; Ramirez, A; Ricci, D; Taira, CA | 1 |
| Kulkarni, SK; Naidu, PS; Raghavendra, V | 1 |
| Bourin, M; Dailly, E; Hascoët, M; Masse, F | 1 |
| Ishola, IO; Olayemi, SO; Umeh, EA; Yemitan, OK | 1 |
1 review(s) available for flumazenil and prazosin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
17 other study(ies) available for flumazenil and prazosin
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Effects of intravenous anesthetics on phosphatidylinositol turnover in rat cerebral cortical prisms.
Topics: Anesthetics, Intravenous; Animals; Cerebral Cortex; Diazepam; Dose-Response Relationship, Drug; Droperidol; Fentanyl; Flumazenil; Inositol Phosphates; Ketamine; Male; Naloxone; Norepinephrine; Phosphatidylinositols; Prazosin; Rats; Rats, Wistar; Thiamylal | 1994 |
Benzodiazepine agonists reverse the effects of noise exposure on central benzodiazepine receptors and cardiac responsiveness.
Topics: Animals; Brain; Clonazepam; Diazepam; Flumazenil; Imidazoles; Male; Myocardium; Noise; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, GABA-A; Stress, Psychological | 1995 |
Central benzodiazepine involvement in clonidine cardiovascular actions.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Atropine Derivatives; Blood Pressure; Carbolines; Cardiovascular Agents; Clonidine; Diazepam; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; Heart Rate; Infusions, Intravenous; Injections, Intraventricular; Male; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, GABA-A; Stereotaxic Techniques; Time Factors; Yohimbine | 1999 |
Reversal of reserpine-induced vacuous chewing movements in rats by melatonin: involvement of peripheral benzodiazepine receptors.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Interactions; Dyskinesia, Drug-Induced; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Isoquinolines; Male; Mastication; Melatonin; Neostriatum; Prazosin; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, GABA-A; Receptors, Melatonin; Reserpine; Tryptamines | 2001 |
Anxiolytic-like effect of milnacipran in the four-plate test in mice: mechanism of action.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Behavior, Animal; Benzylamines; Brain; Cyclopropanes; Dopamine; Dose-Response Relationship, Drug; Fenclonine; Flumazenil; Fluorobenzenes; Idazoxan; Indoles; Ketanserin; Male; Mice; Milnacipran; Motor Activity; Neurotransmitter Uptake Inhibitors; Norepinephrine; Phenols; Prazosin; Punishment; Pyridines; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists | 2005 |
Antidepressant and anxiolytic effects of the methanol root extract of Capparis thonningii: involvement of monoaminergic, cholinergic and GABAergic systems.
Topics: Adrenergic Antagonists; Animals; Anti-Anxiety Agents; Antidepressive Agents; Atropine; Behavior, Animal; Biogenic Monoamines; Capparis; Cholinergic Agents; Cholinergic Neurons; Cyproheptadine; Dopamine Antagonists; Female; Flumazenil; GABA Agents; gamma-Aminobutyric Acid; Immobility Response, Tonic; Male; Metergoline; Methanol; Mice; Muscarinic Antagonists; Plant Extracts; Plant Roots; Prazosin; Serotonin Antagonists; Sulpiride; Yohimbine | 2015 |