flumazenil has been researched along with physostigmine in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (28.57) | 18.7374 |
| 1990's | 6 (28.57) | 18.2507 |
| 2000's | 3 (14.29) | 29.6817 |
| 2010's | 6 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| McNamara, RK; Skelton, RW | 1 |
| Kaniaris, PK; Sarlis, NJ | 1 |
| Kulkarni, SK; Sharma, AC | 1 |
| Mok, MS; Steen, SN; Tu, KT; Wei, TT | 1 |
| Haigh, JR; Lines, CR; Poppleton, P; Preston, GC; Traub, M; Ward, C | 1 |
| Lauven, PM; Stoeckel, H | 1 |
| Bovill, JG; Breimer, LT; Hennis, PJ; Spierdijk, J | 1 |
| Bryere, P; Menini, C; Rektor, I; Silva-Barrat, C | 1 |
| Barbaz, BS; Bergen, KM; Bernard, PS; Boast, CA | 1 |
| Calaminus, JM; Lauven, PM | 1 |
| Bowden, CA; Krenzelok, EP | 1 |
| Fujimoto, JM; Holmes, BB; Rady, JJ | 1 |
| Ebert, U; Kirch, W; Oertel, R | 1 |
| Béchir, M; Keel, M; Meierhans, R; Stocker, R; Stover, JF | 1 |
5 review(s) available for flumazenil and physostigmine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Flumazenil (Ro 15-1788) and physostigmine.
Topics: Awareness; Benzodiazepines; Flumazenil; Humans; Intensive Care Units; Physostigmine | 1988 |
The neuropharmacology of various diazepam antagonists.
Topics: Animals; Benzodiazepinones; Caffeine; Carbolines; Diazepam; Flumazenil; Humans; Physostigmine; Pyrazoles; Receptors, Cell Surface; Receptors, GABA-A; Theophylline | 1983 |
[Antagonists in anesthesia].
Topics: Anesthesia, General; Anesthetics; Anti-Anxiety Agents; Arousal; Flumazenil; Humans; Naloxone; Narcotic Antagonists; Neostigmine; Neuromuscular Blocking Agents; Physostigmine | 1995 |
Clinical applications of commonly used contemporary antidotes. A US perspective.
Topics: Acetylcysteine; Antidotes; Antivenins; Atropine; Deferoxamine; Flumazenil; Humans; Hydroxocobalamin; Naloxone; Physostigmine; Poisoning; Succimer | 1997 |
3 trial(s) available for flumazenil and physostigmine
| Article | Year |
|---|---|
[Comparative study of the antagonizing effect to flunitrazepam between Ro 15-1788 and physostigmine].
Topics: Adult; Female; Flumazenil; Flunitrazepam; Humans; Male; Middle Aged; Physostigmine | 1989 |
The efficacy of flumazenil versus physostigmine after midazolam-alfentanil anaesthesia in man.
Topics: Adult; Alfentanil; Anesthesia; Anesthesia Recovery Period; Double-Blind Method; Female; Fentanyl; Flumazenil; Humans; Male; Midazolam; Nitrous Oxide; Physostigmine; Random Allocation; Vecuronium Bromide | 1988 |
Physostigmine reversal of midazolam-induced electroencephalographic changes in healthy subjects.
Topics: Adult; Analysis of Variance; Antidotes; Brain; Cholinesterase Inhibitors; Chromatography, Liquid; Cross-Over Studies; Double-Blind Method; Electroencephalography; Flumazenil; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Midazolam; Physostigmine; Reference Values | 2000 |
13 other study(ies) available for flumazenil and physostigmine
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors | 2012 |
Assessment of a cholinergic contribution to chlordiazepoxide-induced deficits of place learning in the Morris water maze.
Topics: Acetylcholine; Animals; Chlordiazepoxide; Drug Interactions; Flumazenil; Learning; Male; Memory; Physostigmine; Rats; Receptors, Cholinergic; Receptors, GABA-A; Scopolamine | 1992 |
Physostigmine is equipotent to flumazenil only in excessive doses, while naloxone is ineffective in reversing midazolam anesthesia.
Topics: Animals; Flumazenil; Male; Midazolam; Naloxone; Physostigmine; Rats; Rats, Inbred Strains | 1991 |
Evidence for GABA-BZ receptor modulation in short-term memory passive avoidance task paradigm in mice.
Topics: Animals; Avoidance Learning; Carbolines; Electroshock; Female; Flumazenil; gamma-Aminobutyric Acid; Male; Memory, Short-Term; Mice; Physostigmine; Receptors, GABA-A; Scopolamine | 1990 |
Scopolamine and benzodiazepine models of dementia: cross-reversals by Ro 15-1788 and physostigmine.
Topics: Acoustic Stimulation; Adult; Anti-Anxiety Agents; Attention; Cognition Disorders; Dementia; Disease Models, Animal; Female; Flumazenil; Humans; Male; Memory Disorders; Photic Stimulation; Physostigmine; Psychomotor Performance; Pupil; Reaction Time; Scopolamine | 1989 |
Stimulus-sensitive myoclonus of the baboon Papio papio: pharmacological studies reveal interactions between benzodiazepines and the central cholinergic system.
Topics: Animals; Atropine; Benzodiazepines; Benzodiazepinones; Clonazepam; Drug Interactions; Flumazenil; Myoclonus; Neostigmine; Papio; Parasympathetic Nervous System; Physostigmine; Quinuclidinyl Benzilate | 1986 |
Supraspinal flumazenil inhibits the antianalgesic action of spinal dynorphin A (1-17).
Topics: Analgesia; Analgesics; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Dynorphins; Flumazenil; GABA Agonists; GABA-A Receptor Agonists; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Naltrexone; Physostigmine | 1998 |
Reduced midazolam clearance must be considered in prolonged coma.
Topics: Adult; Anesthetics, Intravenous; Antidotes; Cholinesterase Inhibitors; Coma; Flumazenil; Humans; Male; Metabolic Clearance Rate; Midazolam; Naloxone; Narcotic Antagonists; Physostigmine; Time | 2008 |