flumazenil has been researched along with phenobarbital in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (44.83) | 18.7374 |
| 1990's | 4 (13.79) | 18.2507 |
| 2000's | 6 (20.69) | 29.6817 |
| 2010's | 5 (17.24) | 24.3611 |
| 2020's | 1 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Gallaher, EJ; Phillips, TJ | 1 |
| Commissaris, RL; Ellis, DM; Fontana, DJ; McCloskey, TC | 1 |
| Alpern, HP; McIntyre, TD | 1 |
| Nagatani, T; Sugihara, T; Ueki, S; Yamamoto, T | 1 |
| Bonetti, EP; Burkard, WP; Gabl, M; Hunkeler, W; Lorez, HP; Martin, JR; Moehler, H; Osterrieder, W; Pieri, L; Polc, P | 1 |
| Klockgether, T; Schwarz, M; Sontag, KH; Turski, L | 1 |
| Albrecht, RF; Cook, J; Hoffman, WE; Larscheid, P; Miletich, DJ; Naughton, N | 1 |
| Kawasaki, K; Kodama, M; Matsushita, A | 1 |
| Daniel, M; Dubroeucq, MC; Gauthier, A; Gueremy, C; Mazadier, M; Mizoule, J; Ollat, C; Rataud, J; Renault, C; Uzan, A | 1 |
| Mendelson, WB | 1 |
| Bonetti, EP; Haefely, W; Polc, P; Schaffner, R | 1 |
| De Bonnel, G; De Montigny, C | 1 |
| Vellucci, SV; Webster, RA | 1 |
| Clineschmidt, BV | 1 |
| Steinhoff, BJ; Stodieck, SR | 1 |
| Covey, DF; Ferrendelli, JA; Krause, JE; Rothman, SM; Tucker, JB; Weiss, DS; White, G; Williams, KL | 1 |
| Hamann, M; Richter, A | 1 |
| Groenink, L; Maes, RA; Olivier, B; Oosting, RS; Pattij, T; van der Gugten, J | 1 |
| Löscher, W; Potschka, H; Rieck, S; Rundfeldt, C; Tipold, A | 1 |
| Nordstrom, K; Puening, SE; Wilson, MP | 1 |
| Gharpure, A; Hibbs, RE; Howard, RJ; Kim, JJ; Lindahl, E; Noviello, CM; Teng, J; Walsh, RM; Zhu, S; Zhuang, Y | 1 |
1 review(s) available for flumazenil and phenobarbital
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
28 other study(ies) available for flumazenil and phenobarbital
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Locomotor responses to benzodiazepines, barbiturates and ethanol in diazepam-sensitive (DS) and -resistant (DR) mice.
Topics: Analysis of Variance; Animals; Diazepam; Dose-Response Relationship, Drug; Ethanol; Female; Flumazenil; Flunitrazepam; Male; Mice; Motor Activity; Pentobarbital; Phenobarbital | 1992 |
Chronic anxiolytic treatment effects on conflict behavior in the rat.
Topics: Alprazolam; Animals; Behavior, Animal; Chlordiazepoxide; Conflict, Psychological; Dose-Response Relationship, Drug; Female; Flumazenil; Panic; Phenobarbital; Prohibitins; Rats; Rats, Inbred Strains | 1990 |
Patterns of convulsive susceptibility in the long-sleep and short-sleep selected mouse lines.
Topics: Animals; Anticonvulsants; Bicuculline; Convulsants; Female; Flumazenil; Male; Mice; Pentylenetetrazole; Phenobarbital; Reaction Time; Seizures; Sleep | 1989 |
The effect of agonists at the GABA-benzodiazepine-receptor-complex on the proconflict effect induced by beta-CCM and pentetrazol in rats.
Topics: Aminooxyacetic Acid; Animals; Azabicyclo Compounds; Carbolines; Conflict, Psychological; Convulsants; Diazepam; Flumazenil; Hypnotics and Sedatives; Male; Pentylenetetrazole; Phenobarbital; Piperazines; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1988 |
Ro 15-4513: partial inverse agonism at the BZR and interaction with ethanol.
Topics: Animals; Azides; Behavior, Animal; Benzodiazepines; Brain; Brain Chemistry; Cats; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Ethanol; Flumazenil; Meta-Analysis as Topic; Mice; Phenobarbital; Rats; Receptors, GABA-A | 1988 |
ZK 91296, an anticonvulsant beta-carboline which lacks muscle relaxant properties.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepinones; Carbolines; Convulsants; Diazepam; Electromyography; Electroshock; Flumazenil; Indoles; Male; Mice; Mice, Inbred Strains; Muscle Contraction; Muscle Relaxants, Central; Muscle Tonus; Phenobarbital; Rats; Rats, Inbred Strains | 1985 |
The interaction between benzodiazepine antagonists and barbiturate-induced cerebrovascular and cerebral metabolic depression.
Topics: Animals; Barbiturates; Benzodiazepinones; Brain; Carbolines; Cerebrovascular Circulation; Flumazenil; Male; Oxygen Consumption; Pentobarbital; Phenobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
An imidazodiazepine derivative, Ro 15-1788, behaves as a weak partial agonist in the crossed extensor reflex.
Topics: Animals; Benzodiazepinones; Carbolines; Chlorpromazine; Diazepam; Flumazenil; Male; Phenobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Reflex | 1984 |
Pharmacological evidence that PK 8165 behaves as a partial agonist of brain type benzodiazepine receptors.
Topics: Aggression; Animals; Anticonvulsants; Benzodiazepinones; Conflict, Psychological; Diazepam; Drinking; Flumazenil; Humans; Male; Mice; Mice, Inbred Strains; Phenobarbital; Quinolines; Receptors, GABA-A; Reflex | 1984 |
The benzodiazepine receptor and sleep.
Topics: Animals; Barbiturates; Benzodiazepines; Benzodiazepinones; Calcium; Carbolines; Diazepam; Flumazenil; Flurazepam; Humans; Motor Activity; Nifedipine; Phenobarbital; Pyrazoles; Rats; Receptors, GABA-A; Sleep; Synaptosomes | 1984 |
A three-state model of the benzodiazepine receptor explains the interactions between the benzodiazepine antagonist Ro 15-1788, benzodiazepine tranquilizers, beta-carbolines, and phenobarbitone.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Carbolines; Cats; Female; Flumazenil; Hippocampus; In Vitro Techniques; Indoles; Male; Mice; Models, Biological; Phenobarbital; Rats; Receptors, Cell Surface; Receptors, GABA-A; Spinal Cord | 1982 |
Benzodiazepine selectively antagonize kainate-induced activation in the rat hippocampus.
Topics: Acetylcholine; Animals; Anti-Anxiety Agents; Benzodiazepinones; Chlorpromazine; Diazepam; Flumazenil; Glutamates; Hippocampus; Injections, Intravenous; Iontophoresis; Kainic Acid; Lorazepam; Male; Phenobarbital; Pyramidal Tracts; Pyrrolidines; Rats; Rats, Inbred Strains | 1983 |
Is Ro15-1788 a partial agonist at benzodiazepine receptors?
Topics: Animals; Benzodiazepinones; Bicuculline; Convulsants; Diazepam; Flumazenil; Male; Mice; Mice, Inbred C3H; Phenobarbital; Pyridazines; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Effect of the benzodiazepine receptor antagonist Ro 15-1788 on the anticonvulsant and anticonflict actions of MK-801.
Topics: Animals; Anticonvulsants; Behavior, Animal; Benzodiazepinones; Bicuculline; Chlordiazepoxide; Clonazepam; Conflict, Psychological; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Interactions; Female; Flumazenil; Mice; Phenobarbital; Rats; Rats, Inbred Strains | 1982 |
Temporary abolition of seizure activity by flumazenil in a case of valproate-induced non-convulsive status epilepticus.
Topics: Adult; Anticonvulsants; Drug Therapy, Combination; Electroencephalography; Evoked Potentials; Female; Flumazenil; Humans; Midazolam; Phenobarbital; Seizures; Status Epilepticus; Valproic Acid | 1993 |
Lactone modulation of the gamma-aminobutyric acid A receptor: evidence for a positive modulatory site.
Topics: 4-Butyrolactone; Animals; Chlordiazepoxide; Female; Flumazenil; gamma-Aminobutyric Acid; Lactones; Phenobarbital; Picrotoxin; Receptors, GABA-A; Xenopus laevis | 1997 |
Effects of striatal injections of GABA(A) receptor agonists and antagonists in a genetic animal model of paroxysmal dystonia.
Topics: Animals; Bicuculline; Binding Sites; Corpus Striatum; Cricetinae; Dystonia; Female; Flumazenil; Flurazepam; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Male; Mesocricetus; Microinjections; Muscimol; Pentylenetetrazole; Phenobarbital | 2002 |
GABA(A)-benzodiazepine receptor complex sensitivity in 5-HT(1A) receptor knockout mice on a 129/Sv background.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Diazepam; Ethanol; Fever; Flumazenil; GABA Antagonists; Hypnotics and Sedatives; Male; Maze Learning; Mice; Mice, Knockout; Pentylenetetrazole; Phenobarbital; Receptors, GABA-A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reflex; Species Specificity; Stress, Physiological | 2002 |
Anticonvulsant efficacy of the low-affinity partial benzodiazepine receptor agonist ELB 138 in a dog seizure model and in epileptic dogs with spontaneously recurrent seizures.
Topics: Animals; Anticonvulsants; Bromides; Chronic Disease; Disease Models, Animal; Dog Diseases; Dogs; Drug Therapy, Combination; Epilepsy; Flumazenil; GABA Agonists; GABA-A Receptor Agonists; Imidazoles; Pentylenetetrazole; Phenobarbital; Potassium Compounds; Primidone; Receptors, GABA-A; Seizures; Substance Withdrawal Syndrome; Treatment Outcome | 2004 |
Psychiatric Emergencies for Clinicians: Emergency Department Management of Benzodiazepine Withdrawal.
Topics: Aged; Benzodiazepines; Emergency Service, Hospital; Emergency Services, Psychiatric; Female; Flumazenil; Humans; Phenobarbital; Psychoses, Substance-Induced; Substance Withdrawal Syndrome | 2017 |
Shared structural mechanisms of general anaesthetics and benzodiazepines.
Topics: Allosteric Regulation; Anesthetics, General; Barbiturates; Benzodiazepines; Bicuculline; Binding Sites; Binding, Competitive; Cryoelectron Microscopy; Diazepam; Electrophysiology; Etomidate; Flumazenil; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Ligands; Models, Molecular; Molecular Conformation; Molecular Dynamics Simulation; Phenobarbital; Picrotoxin; Propofol; Receptors, GABA-A | 2020 |