flumazenil has been researched along with pentobarbital in 94 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 48 (51.06) | 18.7374 |
| 1990's | 24 (25.53) | 18.2507 |
| 2000's | 10 (10.64) | 29.6817 |
| 2010's | 10 (10.64) | 24.3611 |
| 2020's | 2 (2.13) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Mody, I; Otis, TS | 1 |
| Gallaher, EJ; Phillips, TJ | 1 |
| Hales, TG; Lambert, JJ | 1 |
| Fukuda, N; Wada, T | 2 |
| Franklin, SR; Tang, AH | 1 |
| Farb, DH; Friedman, L; Gibbs, TT; Roca, DJ; Rozenberg, I; Schiller, GD | 1 |
| Blakeman, DP; Im, WB | 1 |
| Bing, LH; Matsumoto, K; Ohta, H; Satoh, T; Watanabe, H | 1 |
| Budhram, P; Deacon, RM; Gardner, CR; Thomson, TA | 1 |
| Morse, WH; Teeple, ES; Wettstein, JG | 1 |
| Koob, GF; Schreiber, JF; Weinger, MB | 1 |
| Pedemonte, M; Velluti, R | 1 |
| Biggio, G; Corda, MG; Giorgi, O; Longoni, B | 1 |
| Baur, R; Peter, AB; Sigel, E; Yao, Y | 1 |
| Balster, RL; Willetts, J | 1 |
| Evans, SM; Johanson, CE | 1 |
| Bizière, K; Fournier, M; Keane, P; Santucci, V; Worms, P | 1 |
| Hanada, S; Hashimoto, S; Tanaka, C; Taniyama, K | 1 |
| De Medici, D; Gatta, F; Longo, VG; Massotti, M | 1 |
| Leidenheimer, NJ; Schechter, MD | 1 |
| Gogolák, G; Huck, S; Stumpf, C | 1 |
| Harris, C; Lal, H | 1 |
| Garcha, HS; Rose, IC; Stolerman, IP | 2 |
| Ellis, S; Foltin, RW; Schuster, CR | 1 |
| Johanson, CE; Schuster, CR | 1 |
| de la Garza, R; Evans, S; Johanson, CE | 1 |
| Dewey, WL; Glennon, RA; Young, R | 2 |
| Deutsch, SI; Greenblatt, DJ; Miller, LG; Paul, SM; Shader, RI | 1 |
| Spealman, RD | 1 |
| Rastogi, SK; Ticku, MK | 1 |
| Barrett, JE; Brady, LS; Witkin, JM | 1 |
| Albrecht, RF; Cook, J; Hoffman, WE; Larscheid, P; Miletich, DJ; Naughton, N | 1 |
| Simmonds, MA | 1 |
| Cohen, RM; Havoundjian, H; Paul, SM; Skolnick, P | 1 |
| Sweetnam, PM; Tallman, JF | 1 |
| Barrett, JE; Cook, JM; Larscheid, P; Witkin, JM | 1 |
| De Vry, J; Slangen, JL | 1 |
| Havoundjian, H; Paul, SM; Reed, GF; Skolnick, P | 1 |
| Martin, WR; McNicholas, LF | 1 |
| Dhawan, BN; Gulati, A; Singh, HK; Srimal, RC | 1 |
| Biziere, K; Calassi, R; Chambon, JP; Heaulme, M; Perio, A | 1 |
| Majewska, MD; Mienville, JM; Vicini, S | 1 |
| Hiltunen, AJ; Järbe, TU | 1 |
| Longo, VG; Sagratella, S | 1 |
| Chiu, TH; Rosenberg, HC | 1 |
| Gherezghiher, T; Lal, H | 1 |
| Ator, NA; Griffiths, RR | 1 |
| Borea, PA; Karobath, M; Supavilai, P | 1 |
| Clark, JD; Hatch, RC; Kitzman, JV; Zahner, JM | 1 |
| Ashton, D | 1 |
| Mokler, DJ; Rech, RH | 1 |
| Elmesallamy, F; Emmett-Oglesby, M; Lal, H; Lewis, M; Spencer, D | 1 |
| Barzaghi, C; Marzanatti, M; Ongini, E | 1 |
| Emmett-Oglesby, MW; Lal, H; Lewis, MW; Spencer, DG | 1 |
| Schechter, MD | 1 |
| Herling, S; Shannon, HE | 1 |
| Ator, NA; Sannerud, CA | 1 |
| Crabbe, JC; Keith, LD; Roberts, AJ | 1 |
| Hu, XJ; Ticku, MK | 1 |
| Ator, NA; Griffiths, RR; Sannerud, CA | 1 |
| Alastra, AJ; Cohen, C; Goldberg, SR; Marley, RJ; Sannerud, CA; Serdikoff, SL | 1 |
| Abbott, FV; Franklin, KB | 1 |
| Carlen, PL; Weiner, JL; Zhang, L | 1 |
| Drewe, JA; Whittemore, ER; Woodward, RM; Yang, W | 1 |
| Matsumoto, K; Ojima, K; Watanabe, H | 1 |
| Davies, PA; Hales, TG; Hanna, MC; Kirkness, EF | 1 |
| Kohno, SI; Matsumoto, K; Ojima, K; Watanabe, H | 1 |
| Dong, E; Matsumoto, K; Tohda, M; Watanabe, H | 1 |
| Coop, A; France, CP; McMahon, LR; Winger, G; Woolverton, WL | 1 |
| Kulkarni, SK; Kumar, A | 1 |
| France, CP; Gerak, LR; McMahon, LR | 1 |
| Inoue, O; Saito, M; Sakiyama, Y | 1 |
| France, CP; Javors, MA; McMahon, LR | 1 |
| Chu, QP; Cui, XY; Fu, HZ; Lin, SQ; Lin, ZB; Wang, LE; Zhang, YH | 1 |
| Czajkowski, C; Sharkey, LM | 1 |
| Betts, BA; Gill, N; Griffith, TN; Hall, AC; Humbert, DJ; Jenkins, A; Kelly, EW; Kotey, FO; Rowan, KC; Veneskey, KC; Watt, EE | 1 |
| Grant, KA; Helms, CM; Rogers, LS | 1 |
| Egashira, N; Fujiwara, M; Ishibashi, A; Iwasaki, K; Mishima, K; Nishimura, R; Nogami, A; Oishi, R; Takasaki, K; Uchida, N | 1 |
| Baek, NI; Cho, NC; Cho, S; Han, D; Kim, D; Lee, C; No, KT; Pae, AN; Park, JH; Shimizu, M; Yang, H; Yoon, M | 1 |
| Costa, EA; de Brito, AF; De Lima, TC; Fajemiroye, JO; Galdino, PM; Martins, JL; Menegatti, R | 1 |
| Dabole, B; Dawe, A; De Waard, M; Dimo, T; Djomeni Dzeufiet, PD; Ngo Bum, E; Okomolo Moto, FC; Sidiki, N; Sotoing Taïwe, G; Talla, E; Temkou Ngoupaye, G | 1 |
| Cho, S; Han, D; Jin, YH; Jin, Z; Kim, IH; Kim, S | 1 |
| Bi, K; Jia, Y; Li, H; Liu, B; Liu, Z; Mao, X; Zhang, C; Zhao, X | 1 |
| Bi, K; Jia, Y; Li, X; Liu, A; Liu, Z; Mao, X; Zhang, C; Zhao, X | 1 |
| Cho, NC; Cho, S; Kim, J; Lee, CJ; Pae, AN; Park, KD; Um, MY; Woo, J; Yang, H; Yoon, M | 1 |
| He, L; Luo, M; Yao, L; Zhang, N | 1 |
| Chai, X; Chen, S; Gao, X; Huang, L; Jiao, S; Li, J; Ma, X; Tu, P; Wuken, S | 1 |
1 review(s) available for flumazenil and pentobarbital
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
93 other study(ies) available for flumazenil and pentobarbital
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Modulation of decay kinetics and frequency of GABAA receptor-mediated spontaneous inhibitory postsynaptic currents in hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Anesthetics, Local; Animals; Calcium Channels; Evoked Potentials; Flumazenil; Hippocampus; Kinetics; Lidocaine; Mathematics; Meglumine; Membrane Potentials; Midazolam; Models, Neurological; Neurons; Pentobarbital; Probability; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA-A; Synapses; Tetrodotoxin | 1992 |
Locomotor responses to benzodiazepines, barbiturates and ethanol in diazepam-sensitive (DS) and -resistant (DR) mice.
Topics: Analysis of Variance; Animals; Diazepam; Dose-Response Relationship, Drug; Ethanol; Female; Flumazenil; Flunitrazepam; Male; Mice; Motor Activity; Pentobarbital; Phenobarbital | 1992 |
The actions of propofol on inhibitory amino acid receptors of bovine adrenomedullary chromaffin cells and rodent central neurones.
Topics: Adrenal Medulla; Animals; Cattle; Cells, Cultured; Cerebral Cortex; Chromaffin System; Electric Stimulation; Female; Flumazenil; GABA-A Receptor Antagonists; Ion Channel Gating; Mice; Neural Conduction; Neurons; Pentobarbital; Pregnancy; Propofol; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Glycine; Receptors, Neurotransmitter | 1991 |
Pharmacologic profile of a new anxiolytic, DN-2327: effect of Ro15-1788 and interaction with diazepam in rodents.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Conditioning, Operant; Conflict, Psychological; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Flumazenil; Isoindoles; Male; Mice; Mice, Inbred ICR; Muscle Relaxation; Naphthyridines; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Spiro Compounds | 1991 |
The discriminative stimulus effects of diazepam in rats at two training doses.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Buspirone; Carbolines; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Flumazenil; Male; Morphine; Pentobarbital; Pyrazoles; Pyridazines; Rats; Rats, Inbred Strains; Triazolam | 1991 |
gamma-Aminobutyric acidA receptor regulation in culture: altered allosteric interactions following prolonged exposure to benzodiazepines, barbiturates, and methylxanthines.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Allosteric Regulation; Animals; Barbital; Barbiturates; Brain; Caffeine; Cells, Cultured; Chick Embryo; Flumazenil; Flunitrazepam; Flurazepam; gamma-Aminobutyric Acid; Kinetics; Neurons; Pentobarbital; Receptors, GABA-A; Tetrodotoxin; Theophylline; Veratridine | 1990 |
Correlation between gamma-aminobutyric acidA receptor ligand-induced changes in t-butylbicyclophosphoro[35S]thionate binding and 36Cl- uptake in rat cerebrocortical membranes.
Topics: Animals; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Cerebral Cortex; Chloride Channels; Chlorides; Desoxycorticosterone; Diazepam; Ethanol; Flumazenil; gamma-Aminobutyric Acid; In Vitro Techniques; Ligands; Membrane Proteins; Pentobarbital; Pregnanolone; Rats; Receptors, GABA-A; Synaptosomes | 1991 |
Effects of forced shaking stress at low temperature on pentobarbital-induced sleeping in mice.
Topics: Animals; Cold Temperature; Diazepam; Drug Resistance; Flumazenil; Male; Mice; Naloxone; Nociceptors; Pentobarbital; Sleep; Stress, Physiological | 1991 |
Differential interactions of Ro 15-4513 with benzodiazepines, ethanol and pentobarbital.
Topics: Anesthesia; Animals; Anti-Anxiety Agents; Azides; Behavior, Animal; Benzodiazepines; Diazepam; Drug Interactions; Ethanol; Female; Flumazenil; Male; Muscle Contraction; Muscles; Pentobarbital; Rats; Rats, Inbred Strains; Urethane; Vocalization, Animal | 1990 |
Respiratory effects of benzodiazepine-related drugs in awake rhesus monkeys.
Topics: Administration, Inhalation; Alprazolam; Animals; Anti-Anxiety Agents; Appetite Depressants; Benzodiazepines; Buspirone; Carbolines; Carbon Dioxide; Drug Therapy, Combination; Female; Flumazenil; Lorazepam; Macaca mulatta; Male; Pentobarbital; Plethysmography; Pyrazoles; Respiration | 1990 |
Effects of two benzodiazepine inverse agonists, RO 15-4513 and FG 7142, on recovery from pentobarbital and halothane anesthesia in the rat.
Topics: Anesthesia Recovery Period; Animals; Azides; Benzodiazepines; Carbolines; Flumazenil; Halothane; Male; Pentobarbital; Random Allocation; Rats; Rats, Inbred Strains; Reflex | 1990 |
Differential effects of benzodiazepines on cochlear and auditory nerve responses.
Topics: Action Potentials; Animals; Chlordiazepoxide; Cochlear Microphonic Potentials; Evoked Potentials, Auditory; Flumazenil; Guinea Pigs; Midazolam; Pentobarbital; Vestibulocochlear Nerve | 1986 |
Ro 15-4513, a partial inverse agonist for benzodiazepine recognition sites, has proconflict and proconvulsant effects in the rat.
Topics: Animals; Azides; Benzodiazepines; Carbolines; Conflict, Psychological; Convulsants; Flumazenil; Isoniazid; Male; Pentobarbital; Punishment; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1989 |
The tremorigen aflatrem is a positive allosteric modulator of the gamma-aminobutyric acidA receptor channel expressed in Xenopus oocytes.
Topics: Allosteric Regulation; Animals; Chloride Channels; Chlorides; Dose-Response Relationship, Drug; Flumazenil; gamma-Aminobutyric Acid; Indoles; Membrane Proteins; Mycotoxins; Oocytes; Pentobarbital; Picrotoxin; Receptors, GABA-A; Xenopus | 1989 |
Pentobarbital-like discriminative stimulus effects of N-methyl-D-aspartate antagonists.
Topics: Animals; Aspartic Acid; Dibenzocycloheptenes; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Flumazenil; Generalization, Psychological; Male; N-Methylaspartate; Pentobarbital; Phencyclidine; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Discriminative stimulus properties of midazolam in the pigeon.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Buspirone; Columbidae; Discrimination Learning; Dose-Response Relationship, Drug; Flumazenil; Midazolam; Pentobarbital; Pyridazines | 1989 |
Cerebral-activating (EEG) properties of two inverse agonists and of an antagonist at the benzodiazepine receptor in the rat.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Central Nervous System Stimulants; Chlorpromazine; Diazepam; Electroencephalography; Flumazenil; Imipramine; Male; Pentobarbital; Pyrazoles; Pyridazines; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1989 |
Benzodiazepines and barbiturate potentiate the pre- and postsynaptic gamma-aminobutyric acid (GABA)A receptor-mediated response in the enteric nervous system of guinea pig small intestine.
Topics: Acetylcholine; Animals; Barbiturates; Benzodiazepines; Clonazepam; Diazepam; Female; Flumazenil; Guinea Pigs; Intestine, Small; Male; Muscimol; Pentobarbital; Potassium; Receptors, GABA-A | 1988 |
Effects of drugs on the electrical activity of the red nucleus in the rabbit. Activation of benzodiazepine and barbiturate receptors.
Topics: Animals; Bicuculline; Carbolines; Diazepam; Drug Interactions; Electroencephalography; Flumazenil; Muscle Relaxation; Pentobarbital; Pyridazines; Rabbits; Receptors, GABA-A; Receptors, Neurotransmitter; Red Nucleus | 1988 |
Discriminative stimulus properties of CGS 9896: interactions within the GABA/benzodiazepine receptor complex.
Topics: Animals; Carbolines; Chlordiazepoxide; Discrimination, Psychological; Dose-Response Relationship, Drug; Flumazenil; gamma-Aminobutyric Acid; Male; Pentobarbital; Pentylenetetrazole; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1988 |
Differentiation of drug-induced rhythmical activities in the rabbit's brain by a benzodiazepine antagonist.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Brain; Cerebral Cortex; Drug Interactions; Electroencephalography; Flumazenil; Male; Medazepam; Pentobarbital; Purkinje Cells; Rabbits; Red Nucleus | 1985 |
Interoceptive stimuli produced by an anxiogenic drug are mimicked by benzodiazepine antagonists in rats pretreated with isoniazid.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepinones; Brain Chemistry; Convulsants; Discrimination, Psychological; Flumazenil; gamma-Aminobutyric Acid; Humans; Isoniazid; Male; Pentobarbital; Pentylenetetrazole; Pyrazoles; Rats | 1985 |
Midazolam cue in rats: generalization tests with anxiolytic and other drugs.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Cues; Dose-Response Relationship, Drug; Flumazenil; Generalization, Stimulus; Male; Midazolam; Pentobarbital; Rats | 1985 |
Specific antagonism by RO 15-1788 of benzodiazepine-induced increases in food intake in rhesus monkeys.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Bromazepam; Convulsants; Diazepam; Dose-Response Relationship, Drug; Feeding Behavior; Female; Flumazenil; Macaca mulatta; Male; Pentobarbital | 1985 |
The effects of Ro 15-1788 on anxiolytic self-administration in the rhesus monkey.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Drug Interactions; Female; Flumazenil; Flurazepam; Lorazepam; Macaca mulatta; Male; Pentobarbital; Reinforcement, Psychology; Self Administration | 1986 |
Discriminative stimulus properties of oxazepam in the pigeon.
Topics: Animals; Anti-Anxiety Agents; Columbidae; Discrimination Learning; Flumazenil; Oxazepam; Pentobarbital; Pyridazines | 1987 |
Effects of pyrazolopyridines and a triazolopyridazine on the pentobarbital discriminative stimulus.
Topics: Animals; Anti-Anxiety Agents; Discrimination Learning; Discrimination, Psychological; Flumazenil; Generalization, Stimulus; Male; Pentobarbital; Pyrazoles; Pyridazines; Rats; Rats, Inbred Strains | 1987 |
Acute barbiturate administration increases benzodiazepine receptor binding in vivo.
Topics: Animals; Anti-Anxiety Agents; Barbiturates; Brain Chemistry; Clonazepam; Flumazenil; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Male; Mice; Pentobarbital; Receptors, GABA-A | 1988 |
Discriminative-stimulus effects of midazolam in squirrel monkeys: comparison with other drugs and antagonism by Ro 15-1788.
Topics: Animals; Azabicyclo Compounds; Barbital; Benzodiazepines; Benzodiazepinones; Buspirone; Caffeine; Chlordiazepoxide; Cinanserin; Clozapine; Conditioning, Operant; Cyproheptadine; Diazepam; Diphenhydramine; Discrimination Learning; Electroshock; Flumazenil; Male; Midazolam; Muscimol; Nordazepam; Pentobarbital; Piperazines; Pyridazines; Pyrimidines; Saimiri; Tripelennamine | 1985 |
Involvement of a GABAergic mechanism in the anticonvulsant effect of pentobarbital against maximal electroshock-induced seizures in rats.
Topics: Animals; Anticonvulsants; Benzodiazepinones; Bicuculline; Drug Interactions; Electroshock; Ethanol; Flumazenil; GABA Antagonists; gamma-Aminobutyric Acid; Male; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Sleep | 1985 |
Behavioral studies with anxiolytic drugs. I. Interactions of the benzodiazepine antagonist Ro 15-1788 with chlordiazepoxide, pentobarbital and ethanol.
Topics: Animals; Behavior, Animal; Benzodiazepines; Benzodiazepinones; Chlordiazepoxide; Dose-Response Relationship, Drug; Electroshock; Ethanol; Female; Flumazenil; Food; Male; Pentobarbital; Punishment; Receptors, GABA-A; Reinforcement, Psychology; Saimiri | 1985 |
The interaction between benzodiazepine antagonists and barbiturate-induced cerebrovascular and cerebral metabolic depression.
Topics: Animals; Barbiturates; Benzodiazepinones; Brain; Carbolines; Cerebrovascular Circulation; Flumazenil; Male; Oxygen Consumption; Pentobarbital; Phenobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
Antagonism of flurazepam and other effects of Ro15-1788, PK8165 and Ro5-4864 on the GABA-A receptor complex in rat cuneate nucleus.
Topics: Animals; Anticonvulsants; Benzodiazepinones; Drug Synergism; Flumazenil; Flurazepam; In Vitro Techniques; Male; Medulla Oblongata; Muscimol; Pentobarbital; Picrotoxin; Quinolines; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
Differential sensitivity of "central" and "peripheral" type benzodiazepine receptors to phospholipase A2.
Topics: Animals; Benzodiazepinones; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Cerebral Cortex; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Kidney; Male; Myocardium; Pentobarbital; Phospholipases; Phospholipases A; Phospholipases A2; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1986 |
Regional difference in brain benzodiazepine receptor carbohydrates.
Topics: Acetylglucosaminidase; Animals; Asparagine; Benzodiazepinones; Brain Chemistry; Carbohydrates; Electrophoresis, Polyacrylamide Gel; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Male; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Molecular Weight; Muscimol; Neuraminidase; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sialic Acids; Tritium | 1986 |
Differential antagonism of diazepam-induced loss of the righting response.
Topics: Animals; Benzodiazepinones; Carbolines; Columbidae; Diazepam; Flumazenil; Inosine; Male; Pentobarbital; Posture; Receptors, GABA-A; Reflex; Saimiri | 1986 |
Differential interactions between chlordiazepoxide, pentobarbital and benzodiazepine antagonists Ro 15-1788 and CGS 8216 in a drug discrimination procedure.
Topics: Animals; Benzodiazepinones; Chlordiazepoxide; Conditioning, Operant; Cues; Discrimination Learning; Drug Interactions; Flumazenil; Generalization, Stimulus; Male; Pentobarbital; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1986 |
Midazolam cue in rats: effects of Ro 15-1788 and picrotoxin.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Discrimination, Psychological; Dose-Response Relationship, Drug; Flumazenil; gamma-Aminobutyric Acid; Male; Midazolam; Nicotine; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A | 1986 |
Protection against the lethal effects of pentobarbital in mice by a benzodiazepine receptor inverse agonist, 6,7-dimethoxy-4-ethyl-3-carbomethoxy-beta-carboline.
Topics: Animals; Carbolines; Flumazenil; Male; Mice; Mice, Inbred Strains; Pentobarbital; Receptors, GABA-A | 1987 |
Benzodiazepine antagonist, CGS-8216, in diazepam- or pentobarbital-dependent and non-dependent rats.
Topics: Animals; Arousal; Diazepam; Dose-Response Relationship, Drug; Female; Flumazenil; Pentobarbital; Pyrazoles; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Substance-Related Disorders | 1986 |
Effect of RO 15-1788 on diazepam, GABA & pentobarbitone induced EEG changes in rabbits.
Topics: Animals; Cerebral Cortex; Diazepam; Electroencephalography; Electromyography; Female; Flumazenil; gamma-Aminobutyric Acid; Male; Pentobarbital; Rabbits | 1986 |
Evaluation of two anticonvulsant amino-pyridazine derivatives in the conflict test in rats.
Topics: Animals; Anticonvulsants; Conflict, Psychological; Diazepam; Flumazenil; Meprobamate; Mice; Papio; Pentobarbital; Pyrazoles; Pyridazines; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Valproic Acid | 1986 |
Neurosteroid pregnenolone sulfate antagonizes electrophysiological responses to GABA in neurons.
Topics: Action Potentials; Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Cerebral Cortex; Flumazenil; gamma-Aminobutyric Acid; Pentobarbital; Pregnenolone; Rats; Steroids | 1988 |
Effects of Ro 15-4513, alone or in combination with ethanol, Ro 15-1788, diazepam, and pentobarbital on instrumental behaviors of rats.
Topics: Animals; Azides; Behavior, Animal; Benzodiazepines; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Female; Flumazenil; Pentobarbital; Rats; Rats, Inbred Strains; Time Factors | 1988 |
An EEG investigation on the role of cerebello-rubral system in the effects of diazepam and pentobarbital.
Topics: Animals; Benzodiazepinones; Cerebellum; Diazepam; Electroencephalography; Female; Flumazenil; Male; Pentobarbital; Pentylenetetrazole; Picrotoxin; Rabbits; Red Nucleus | 1985 |
Comparison of the kinetics of [3H]diazepam and [3H]flunitrazepam binding to cortical synaptosomal membranes.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Cerebral Cortex; Diazepam; Filtration; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Male; Pentobarbital; Rats; Rats, Inbred Strains; Sodium Chloride; Synaptic Membranes | 1982 |
RO 15-1788 selectively reverses antagonism of pentylenetetrazol-induced discriminative stimuli by benzodiazepines but not by barbiturates.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Benzodiazepinones; Diazepam; Flumazenil; Male; Pentobarbital; Pentylenetetrazole; Rats; Stimulation, Chemical | 1982 |
Lorazepam and pentobarbital drug discrimination in baboons: cross-drug generalization and interaction with Ro 15-1788.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Drug Interactions; Flumazenil; Generalization, Response; Lorazepam; Male; Papio; Pentobarbital | 1983 |
Differential modulation of etazolate or pentobarbital enhanced [3H] muscimol binding by benzodiazepine agonists and inverse agonists.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Binding, Competitive; Carbolines; Cell Membrane; Cerebral Cortex; Convulsants; Etazolate; Flumazenil; Flunitrazepam; Kinetics; Muscimol; Nicotinic Acids; Oxazoles; Pentobarbital; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Comparison of five preanesthetic medicaments in thiopental-anesthetized cats: antagonism by selected compounds.
Topics: 4-Aminopyridine; Acepromazine; Aminopyridines; Anesthesia, General; Animals; Arousal; Benzodiazepinones; Cats; Central Nervous System Stimulants; Convulsants; Diazepam; Drug Antagonism; Female; Flumazenil; Ketamine; Male; Meperidine; Naloxone; Pentobarbital; Preanesthetic Medication; Sodium Chloride; Xylazine; Yohimbine | 1984 |
Diazepam, pentobarbital and D-etomidate produced increases in bicuculline seizure threshold; selective antagonism by RO15-1788, picrotoxin and (+/-)-DMBB.
Topics: Animals; Barbiturates; Benzodiazepinones; Bicuculline; Diazepam; Etomidate; Flumazenil; Imidazoles; Male; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Seizures | 1983 |
Stereoselective stimulus effects of 3-methylflunitrazepam and pentobarbital.
Topics: Animals; Benzodiazepinones; Discrimination Learning; Flumazenil; Generalization, Stimulus; Male; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Stereoisomerism | 1984 |
Diazepam, pentobarbital, and methaqualone effects on several behaviors in the rat and antagonism by Ro 15-1788.
Topics: Animals; Behavior, Animal; Benzodiazepinones; Diazepam; Female; Flumazenil; Methaqualone; Pentobarbital; Postural Balance; Rats; Rats, Inbred Strains | 1983 |
Anxiogenic aspects of diazepam withdrawal can be detected in animals.
Topics: Animals; Anxiety; Benzodiazepinones; Diazepam; Discrimination Learning; Flumazenil; Humans; Male; Pentobarbital; Pentylenetetrazole; Rats; Substance Withdrawal Syndrome | 1983 |
Intrinsic and antagonistic effects of beta-carboline FG 7142 on behavioral and EEG actions of benzodiazepines and pentobarbital in cats.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Benzodiazepines; Benzodiazepinones; Carbolines; Cats; Diazepam; Drug Interactions; Electroencephalography; Flumazenil; Indoles; Male; Pentobarbital | 1983 |
Bioassay of subjective effects associated with benzodiazepine withdrawal in animals: a novel direction in dependence research.
Topics: Animals; Benzodiazepinones; Biological Assay; Clonidine; Conditioning, Operant; Diazepam; Discrimination Learning; Flumazenil; Generalization, Stimulus; Humans; Male; Pentobarbital; Pentylenetetrazole; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders | 1984 |
Specific antagonism of the behavioral effects of chlordiazepoxide and pentobarbital in the rat.
Topics: Animals; Bemegride; Benzodiazepinones; Chlordiazepoxide; Cues; Discrimination Learning; Dose-Response Relationship, Drug; Flumazenil; Male; Pentobarbital; Rats; Rats, Inbred Strains; Transfer, Psychology | 1984 |
Ro 15-1788 antagonizes the discriminative stimulus effects of diazepam in rats but not similar effects of pentobarbital.
Topics: Animals; Benzodiazepinones; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Flumazenil; Kinetics; Male; Pentobarbital; Rats; Rats, Inbred F344 | 1982 |
Drug discrimination analysis of midazolam under a three-lever procedure: I. Dose-dependent differences in generalization and antagonism.
Topics: Animals; Caffeine; Cocaine; Dextroamphetamine; Discrimination Learning; Dose-Response Relationship, Drug; Flumazenil; Male; Methocarbamol; Midazolam; Morphine; Pentobarbital; Rats; Rats, Sprague-Dawley | 1995 |
Discriminative stimulus properties of a new anxiolytic, DN-2327, in rats.
Topics: Animals; Anti-Anxiety Agents; Buspirone; Cues; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Flumazenil; Generalization, Stimulus; Isoindoles; Male; Naphthyridines; Pentobarbital; Pentylenetetrazole; Rats; Rats, Wistar; Spiro Compounds | 1993 |
Corticosterone increases severity of acute withdrawal from ethanol, pentobarbital, and diazepam in mice.
Topics: Animals; Behavior, Animal; Corticosterone; Diazepam; Ethanol; Female; Flumazenil; Handling, Psychological; Mice; Mice, Inbred Strains; Pentobarbital; Seizures; Substance Withdrawal Syndrome | 1994 |
Chronic flurazepam treatment produces decreased efficacy of the benzodiazepine ligands and pentobarbital with gamma-aminobutyric acidA receptors in cortical neurons.
Topics: Animals; Benzodiazepines; Biological Transport; Cells, Cultured; Cerebral Cortex; Chlorides; Female; Flumazenil; Flurazepam; Ligands; Male; Mice; Mice, Inbred C57BL; Neurons; Pentobarbital; Receptors, GABA | 1994 |
Behavioral pharmacology of tandospirone in baboons: chronic administration and withdrawal, self-injection and drug discrimination.
Topics: Animals; Anti-Anxiety Agents; Arousal; Buspirone; Cocaine; Discrimination Learning; Dose-Response Relationship, Drug; Eating; Flumazenil; Isoindoles; Lorazepam; Male; Motor Skills; Neurologic Examination; Papio; Pentobarbital; Piperazines; Pyrimidines; Reinforcement Schedule; Self Administration; Serotonin Receptor Agonists; Substance Withdrawal Syndrome; Substance-Related Disorders | 1993 |
Tolerance to the behavioral effects of chlordiazepoxide: pharmacological and biochemical selectivity.
Topics: Amphetamine; Animals; Behavior, Animal; Caffeine; Carbolines; Chlordiazepoxide; Chlorides; Chlorine; Dose-Response Relationship, Drug; Drug Tolerance; Flumazenil; gamma-Aminobutyric Acid; Male; Midazolam; Morphine; Pentobarbital; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sensitivity and Specificity; Stimulation, Chemical | 1993 |
Pentobarbital, diazepam, and ethanol abolish the interphase diminution of pain in the formalin test: evidence for pain modulation by GABAA receptors.
Topics: Analgesics; Animals; Chloride Channels; Diazepam; Ethanol; Flumazenil; Formaldehyde; Male; Pain Measurement; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A | 1993 |
Potentiation of gamma-aminobutyric acid type A receptor-mediated synaptic currents by pentobarbital and diazepam in immature hippocampal CA1 neurons.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Diazepam; Drug Synergism; Flumazenil; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Neurons; Pentobarbital; Rats; Rats, Wistar; Receptors, GABA-A; Synapses | 1993 |
Pharmacology of the human gamma-aminobutyric acidA receptor alpha 4 subunit expressed in Xenopus laevis oocytes.
Topics: Animals; Benzodiazepines; Binding Sites; Diazepam; Electrophysiology; Flumazenil; GABA Agonists; GABA Antagonists; GABA Modulators; Humans; Macromolecular Substances; Pentobarbital; Receptors, GABA-A; Sensitivity and Specificity; Xenopus laevis | 1996 |
Flumazenil reverses the decrease in the hypnotic activity of pentobarbital by social isolation stress: are endogenous benzodiazepine receptor ligands involved?
Topics: Animals; Carbolines; Chlorides; Diazepam; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; Hypnotics and Sedatives; In Vitro Techniques; Ligands; Male; Mice; Mice, Inbred Strains; Pentobarbital; Receptors, GABA-A; Sleep; Social Isolation; Stress, Psychological; Synaptosomes | 1997 |
Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit.
Topics: Amino Acid Sequence; Anesthetics, Intravenous; Animals; Bicuculline; Brain; Cell Line; Consensus Sequence; DNA, Complementary; Flumazenil; Flunitrazepam; GABA Agents; gamma-Aminobutyric Acid; Humans; Molecular Sequence Data; Muscimol; Pentobarbital; Picrotoxin; Pregnanolone; Propofol; Rats; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Transfection | 1997 |
Flumazenil but not FG7142 reverses the decrease in pentobarbital sleep caused by activation of central noradrenergic systems in mice.
Topics: Animals; Appetite Depressants; Carbolines; Cerebral Ventricles; Flumazenil; Injections, Intravenous; Injections, Intraventricular; Male; Methoxamine; Mice; Mice, Inbred Strains; Pentobarbital; Sleep; Yohimbine | 1997 |
Involvement of diazepam binding inhibitor and its fragment octadecaneuropeptide in social isolation stress-induced decrease in pentobarbital sleep in mice.
Topics: Animals; Carrier Proteins; Diazepam Binding Inhibitor; Flumazenil; Hypnotics and Sedatives; Male; Mice; Neuropeptides; Pentobarbital; Peptide Fragments; Sleep; Social Isolation; Stress, Psychological | 1999 |
Evaluation of the reinforcing and discriminative stimulus effects of 1,4-butanediol and gamma-butyrolactone in rhesus monkeys.
Topics: 4-Butyrolactone; Animals; Butylene Glycols; Discrimination Learning; Flumazenil; GABA Modulators; Injections, Intravenous; Macaca mulatta; Male; Midazolam; Pentobarbital; Receptors, GABA-A; Reinforcement, Psychology; Self Administration | 2003 |
Protective effect of BR-16A, a polyherbal preparation against social isolation stress: possible GABAergic mechanism.
Topics: Animals; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Female; Flumazenil; GABA Agonists; gamma-Aminobutyric Acid; Male; Mice; Motor Activity; Pain; Pentobarbital; Phytotherapy; Plant Extracts; Social Isolation; Stress, Psychological | 2006 |
Efficacy and the discriminative stimulus effects of negative GABAA modulators, or inverse agonists, in diazepam-treated rhesus monkeys.
Topics: Animals; Azides; Benzodiazepines; Conditioning, Operant; Cues; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Agonists; GABA Modulators; Hypnotics and Sedatives; Macaca mulatta; Male; Pentobarbital; Pregnanolone; Receptors, GABA-A | 2006 |
Acute treatment with pentobarbital alters the kinetics of in vivo receptor binding in the mouse brain.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Flumazenil; GABA-A Receptor Antagonists; Hypnotics and Sedatives; Kinetics; Male; Metabolic Clearance Rate; Mice; Mice, Inbred Strains; Pentobarbital; Protein Binding; Radioisotope Dilution Technique; Radionuclide Imaging; Radiopharmaceuticals; Receptors, GABA-A; Tissue Distribution; Tritium | 2006 |
Changes in relative potency among positive GABA(A) receptor modulators upon discontinuation of chronic benzodiazepine treatment in rhesus monkeys.
Topics: Animals; Behavior, Animal; Benzodiazepines; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Modulators; Lorazepam; Macaca mulatta; Male; Midazolam; Pentobarbital; Pregnanediones; Pregnanolone; Receptors, GABA-A; Substance Withdrawal Syndrome | 2007 |
Extract of Ganoderma lucidum potentiates pentobarbital-induced sleep via a GABAergic mechanism.
Topics: Animals; Drug Synergism; Drugs, Chinese Herbal; Flumazenil; GABA Modulators; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Mice; Mice, Inbred ICR; Motor Activity; Pentobarbital; Rats; Rats, Sprague-Dawley; Reishi; Sleep; Sleep, REM | 2007 |
Individually monitoring ligand-induced changes in the structure of the GABAA receptor at benzodiazepine binding site and non-binding-site interfaces.
Topics: Animals; Benzodiazepines; Binding Sites; Cysteine; Dose-Response Relationship, Drug; Electrophysiology; Female; Flumazenil; Flurazepam; GABA Agonists; GABA Antagonists; GABA Modulators; Inhibitory Concentration 50; Ligands; Microinjections; Muscimol; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Pentobarbital; Pyridazines; Rats; Receptors, GABA-A; Xenopus | 2008 |
Menthol shares general anesthetic activity and sites of action on the GABA(A) receptor with the intravenous agent, propofol.
Topics: Anesthetics, General; Anesthetics, Intravenous; Animals; Cyclohexanols; Flumazenil; Flunitrazepam; Menthol; Pentobarbital; Pregnanolone; Propofol; Receptors, GABA-A; Xenopus | 2008 |
Antagonism of the ethanol-like discriminative stimulus effects of ethanol, pentobarbital, and midazolam in cynomolgus monkeys reveals involvement of specific GABA(A) receptor subtypes.
Topics: Animals; Azides; Benzodiazepines; Discrimination Learning; Dose-Response Relationship, Drug; Ethanol; Female; Flumazenil; Macaca fascicularis; Male; Midazolam; Pentobarbital; Protein Subunits; Receptors, GABA-A | 2009 |
Yokukansan enhances pentobarbital-induced sleep in socially isolated mice: possible involvement of GABA(A)-benzodiazepine receptor complex.
Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Synergism; Drugs, Chinese Herbal; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Hypnotics and Sedatives; Male; Medicine, Kampo; Mice; Mice, Inbred Strains; Pentobarbital; Receptors, GABA-A; Sleep; Sleep Wake Disorders; Social Isolation; Stress, Psychological | 2011 |
Hypnotic effects and GABAergic mechanism of licorice (Glycyrrhiza glabra) ethanol extract and its major flavonoid constituent glabrol.
Topics: Animals; Dose-Response Relationship, Drug; Ethanol; Eye Movements; Flavanones; Flavonoids; Flumazenil; GABA-A Receptor Antagonists; Glycyrrhiza; Hypnotics and Sedatives; Ligands; Mice; Mice, Inbred C57BL; Molecular Structure; Pentobarbital; Plant Extracts; Plant Preparations; Receptors, GABA-A; Sleep | 2012 |
Central pharmacological activity of a new piperazine derivative: 4-(1-phenyl-1h-pyrazol-4-ylmethyl)-piperazine-1-carboxylic acid ethyl ester.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Dose-Response Relationship, Drug; Flumazenil; Male; Maze Learning; Mice; Pentobarbital; Piperazines; Pyrazoles; Serotonin; Sleep; Time Factors | 2012 |
Antipsychotic and sedative effects of the leaf extract of Crassocephalum bauchiense (Hutch.) Milne-Redh (Asteraceae) in rodents.
Topics: Animals; Antipsychotic Agents; Apomorphine; Asteraceae; Behavior, Animal; Body Temperature; Brain; Catalepsy; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Agents; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Medicine, African Traditional; Mice; Mice, Inbred Strains; Motor Activity; Pentobarbital; Phytotherapy; Plant Extracts; Plant Leaves; Psychotic Disorders; Rats, Sprague-Dawley; Receptors, GABA-A; Sleep; Valproic Acid | 2012 |
Potentiating effect of glabridin on GABAA receptor-mediated responses in dorsal raphe neurons.
Topics: Animals; Anti-Anxiety Agents; Brain; Diazepam; Dose-Response Relationship, Drug; Flumazenil; GABA Agents; gamma-Aminobutyric Acid; Glycyrrhiza; Hypnotics and Sedatives; Isoflavones; Neurons; Pentobarbital; Phenols; Plant Extracts; Plant Roots; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Zolpidem | 2013 |
Gomisin N isolated from Schisandra chinensis augments pentobarbital-induced sleep behaviors through the modification of the serotonergic and GABAergic system.
Topics: Animals; Behavior, Animal; Cyclooctanes; Disease Models, Animal; Drug Synergism; Flumazenil; Fruit; GABA Agents; Hypnotics and Sedatives; Lignans; Male; Mice; Pentobarbital; Polycyclic Compounds; Schisandra; Serotonin Agents; Sleep; Sleep Initiation and Maintenance Disorders | 2014 |
Pharmacological evaluation of sedative and hypnotic effects of schizandrin through the modification of pentobarbital-induced sleep behaviors in mice.
Topics: 5-Hydroxytryptophan; Animals; Caffeine; Cyclooctanes; Fenclonine; Flumazenil; Fruit; GABA Antagonists; Hypnotics and Sedatives; Lignans; Locomotion; Male; Mice; Pentobarbital; Polycyclic Compounds; Sleep | 2014 |
α-Pinene, a Major Constituent of Pine Tree Oils, Enhances Non-Rapid Eye Movement Sleep in Mice through GABAA-benzodiazepine Receptors.
Topics: Animals; Benzodiazepines; Bicyclic Monoterpenes; Binding Sites; Eye Movements; Flumazenil; Inhibitory Postsynaptic Potentials; Male; Mice, Inbred C57BL; Mice, Inbred ICR; Models, Molecular; Monoterpenes; Pentobarbital; Pinus; Plant Oils; Pyridines; Receptors, GABA-A; Sleep; Sleep, REM; Time Factors; Wakefulness; Zolpidem | 2016 |
Chemical Composition of Essential Oil from Flower of 'Shanzhizi' (
Topics: Administration, Inhalation; Animals; Anti-Anxiety Agents; Biogenic Monoamines; Cyclohexanes; Disease Models, Animal; Drugs, Chinese Herbal; Elevated Plus Maze Test; Flumazenil; Gardenia; Gas Chromatography-Mass Spectrometry; Hypnotics and Sedatives; Male; Mice, Inbred ICR; Oils, Volatile; Pentobarbital; Piperazines; Prefrontal Cortex; Receptors, Neurotransmitter; Sleep; Sulpiride; Synaptic Transmission | 2020 |
Zerumbone, a major sesquiterpene from Syringa pinnatifolia Hemsl., exerts the sedative effect by regulating GABAergic nervous system.
Topics: Animals; Bicuculline; Chlorides; Flumazenil; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Mice; Molecular Docking Simulation; Nervous System; Pentobarbital; Plant Extracts; Rats; Receptors, GABA-A; Sesquiterpenes; Syringa | 2023 |