flumazenil and naloxone

flumazenil has been researched along with naloxone in 120 studies

Research

Studies (120)

Timeframe	Studies, this research(%)	All Research%
pre-1990	22 (18.33)	18.7374
1990's	47 (39.17)	18.2507
2000's	26 (21.67)	29.6817
2010's	23 (19.17)	24.3611
2020's	2 (1.67)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Durcan, MJ; Morgan, PF	1
McNamara, RK; Skelton, RW	1
Sim, MK; Tsoi, WF	1
Chakrabarti, MK; Galletly, DC; Wang, C; Whitwam, JG	1
Gent, JP; Goodchild, CS; Serrao, JM	1
Boulter, N; Gent, JP; Goodchild, CS; Serrao, JM	1
Kaniaris, PK; Sarlis, NJ	1
Cruccu, G; Fabbri, A; Ferracuti, S; Leardi, MG; Manfredi, M	1
Bing, LH; Matsumoto, K; Ohta, H; Satoh, T; Watanabe, H	1
Feuerstein, G; Paakkari, I; Paakkari, P; Sirén, AL	1
Burin, LJ; Cardinali, DP; De Brito Sánchez, MG; Escolar, E; Golombek, DA	1
Bilsky, EJ; Marglin, SH; Reid, LD	1
Achtari, R; Baasch, K; Schaer, H	1
Bianchi, M; Fumagalli, P; Mantegazza, P; Panerai, AE; Rovati, LC; Sacerdote, P	1
Sabbe, MB; Stevens, CW; Yaksh, TL; Yanez, A	1
Hall, RI; Hug, CC; Schwieger, IM; Szlam, F	1
Cappell, H; Knoke, DM; Lê, AD; Poulos, CX	1
Innes, DG; Kavaliers, M	2
Hofer, P; Scollo-Lavizzari, G	1
Kubota, K; Matsuda, I; Matsuoka, Y; Sugaya, K; Terawaki, Y	1
Kubota, K; Matsuda, I; Sugaya, K	1
Feuerstein, G; Paakkari, P	1
Barber, DJ; Cooper, SJ; Jackson, A; Moores, WR	1
Boeck, G; Ciaramelli, F; Freye, E; Schaal, M	1
Kulkarni, SK; Kunchandy, J	1
Buéno, L; Fargeas, MJ; Fioramonti, J	1
Freye, E; Schaal, M; Windelschmidt, R	1
Levin, ED; Liebeskind, JC; Morgan, MM	1
Kavaliers, M; Wiebe, JP	2
Davidovich, S; Geller, E; Niv, D; Urca, G	1
Kavaliers, M	1
Barrett, JE; Brady, LS; Mansbach, RS; Muldoon, SM; Skurdal, DN	1
Jackson, HC; Sewell, RD	1
Overstreet, D; Pilotto, R; Singer, G	1
Clark, JD; Hatch, RC; Kitzman, JV; Zahner, JM	1
Colwell, DD; Kavaliers, M	1
Goldfrank, LR; Hoffman, RS	1
Fujigaki, T; Makita, T; Nakamura, H; Shibata, O; Sumikawa, K; Tsujita, T	1
Hayashi, T; Hill, HF; Lorenz, IH; Luger, TJ	1
Cartmell, SM; Mitchell, D	2
Harris, JA; Westbrook, RF	1
Harris, JA; McGregor, IS; Westbrook, RF	1
Jeske, AH; Redden, RJ	1
Fernández-Guasti, A; Saldívar-González, A	1
Crosbie, GV; Grice, JE; Hockings, GI; Jackson, RV; Torpy, DJ; Walters, MM	1
Carr, SV; Frischer, M; Goldberg, DJ; Green, ST; Gruer, L; Taylor, A	1
Feuerstein, G; Landes, P; Paakkari, I; Paakkari, P; Sirén, AL	1
Doyon, S; Roberts, JR	1
Monotti, R	1
Jacobsen, D	1
Calaminus, JM; Lauven, PM	1
Proudfoot, AT	1
Benson, GJ; Lemke, KA; Olson, WA; Thurmon, JC; Tranquilli, WJ	1
Perry, HE; Shannon, MW	1
Brown, RE; Dastur, FN; McGregor, IS; McLellan, RA	1
Bowden, CA; Krenzelok, EP	1
Arias, C; Mondragón-Ceballos, R; Saldívar-González, A	1
Civeira, E; Ferrer, A; Lopez, P; Loren, B	1
Cooper, SJ; Higgs, S	1
Hesselbjerg, L; Koscielniak-Nielsen, ZJ; Stens-Pedersen, HL	1
Gobaille, S; Maitre, M; Pain, L; Sandner, G; Schmidt-Mutter, C	1
Kasaba, T; Takasaki, M; Takeshita, M	1
Fujimoto, JM; Holmes, BB; Rady, JJ	1
Cordero, JA; Durán-Herrera, C; Ramírez-Moreno, JM	1
Murata, Y	1
Büttner, T; Dworzak, H; Fuss, F	1
Buylaert, WA	1
Britton, KT; Southerland, S	1
Dawson, GR; Ferris, P; Seward, E	1
Cremades, A; Peñafiel, R; Pinilla, L; Tejada, F	1
Horne, WA; Kelly, BT; Larsen, RS; Loomis, MR; Sladky, KK; Stoskopf, MK	1
Bledsoe, BE	1
Jennings, CA; Siddiqi, M	1
Bartlett, D	1
Dehne, MG; Engel, J; Fuchs, M; Gonter, J; Hempelmann, G; Krüll, M; Matejec, R; Menges, T; Mühling, J; Nickolaus, KA; Sablotzki, A; Welters, ID; Wolff, M	1
Cappell, MS	1
Collier, CB	1
Breese, GR; Knapp, DJ; Overstreet, DH	1
Nassiri-Asl, M; Shariati-Rad, S; Zamansoltani, F	1
Dhir, A; Kaushal, A; Kulkarni, SK	1
Ozaki, S	1
Bjornas, MA; Ekeberg, O; Heyerdahl, F; Hovda, KE; Jacobsen, D; Opdahl, A; Skog, K; Wium, C	1
Abubakar, MS; Anuka, JA; Hussaini, IM; Ya'u, J; Yaro, AH	1
Béchir, M; Keel, M; Meierhans, R; Stocker, R; Stover, JF	1
Chiba, S; Nishiyama, T; Yamada, Y	1
Creighton, P; Heard, C; Lerman, J	1
Kunitake, T; Shirasaka, T; Tsuneyoshi, I	1
Facco, E; Favero, L; Manani, G; Zanette, G	1
Baud, FJ; Buisine, A; Chevillard, L; Jacobs, F; Mégarbane, B; Résière, D; Vicaut, E	1
Gerónimo Pardo, M; Mateo Cerdán, CM; Moreno Salcedo, JM	1
Bamias, G; Morse, J	1
Kanmura, Y; Moriyama, T; Tsuneyoshi, I	1
Fan, HG; Kun, M; Lu, DZ; Ming, YS; Sheng, J; Song, ZL; Wang, HB	1
Graubard, M; Jang, T; Rohdenberg, P	1
Akanmu, MA; Bamitale, KD; Ukponmwan, OE	1
Gruca, P; Lason-Tyburkiewicz, M; Litwa, E; Papp, M; Willner, P	1
Espinosa, JL; Martinez Miguel, P; Rodriguez Puyol, D; Samillán, K; Sencion Martinez, GL; Villa, P	1
Barnett, S; Falchuk, ZM; Hung, A; Leffler, DA; Marshall, J; Sawhney, M	1
Sivilotti, ML	1
Mehrzadi, S; Motevalian, M; Pur, SA; Shojaii, A	1
Arras, M; Cesarovic, N; Fleischmann, T; Henke, J; Jirkof, P	1
Vicari, JJ	1
Bailey, AM; Baum, RA; Horn, K; Justice, SN; Lewis, T; Morizio, K; Schultz, A; Weant, K	1
Caumo, W; Dos Santos, ARS; Martins, DF; Martins, TC; Medeiros, LF; Nucci-Martins, C; Siteneski, A; Souza, A; Torres, ILS	1
Augustino, M; Duncan, R; Feemster, A; Rowcliffe, M; Smith, J	1
Corrêa Benedet Baesso, K; De Sá Soares, A; Schuelter-Trevisol, F; Zapelini do Nascimento, D	1

Reviews

17 review(s) available for flumazenil and naloxone

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
The poisoned patient with altered consciousness. Controversies in the use of a 'coma cocktail'. JAMA, 1995, Aug-16, Volume: 274, Issue:7 Topics: Consciousness; Flumazenil; Glucose; Humans; Naloxone; Poisoning; Thiamine	1995
Narcotic/sedative receptor antagonists. The Journal of the Greater Houston Dental Society, 1993, Volume: 64, Issue:10 Topics: Anesthesia, Dental; Anti-Anxiety Agents; Binding, Competitive; Conscious Sedation; Drug Interactions; Emergencies; Flumazenil; Humans; Midazolam; Naloxone; Narcotic Antagonists; Receptors, GABA-A; Receptors, Opioid	1993
Reappraisal of the "coma cocktail". Dextrose, flumazenil, naloxone, and thiamine. Emergency medicine clinics of North America, 1994, Volume: 12, Issue:2 Topics: Animals; Coma; Emergencies; Flumazenil; Glucose; Humans; Naloxone; Thiamine	1994
[Drug emergencies]. Schweizerische medizinische Wochenschrift, 1993, May-01, Volume: 123, Issue:17 Topics: Acute Disease; Cocaine; Combined Modality Therapy; Critical Care; Drug Overdose; Flumazenil; Humans; Naloxone; Opioid-Related Disorders	1993
[Antagonists in anesthesia]. Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1995, Volume: 30, Issue:6 Topics: Anesthesia, General; Anesthetics; Anti-Anxiety Agents; Arousal; Flumazenil; Humans; Naloxone; Narcotic Antagonists; Neostigmine; Neuromuscular Blocking Agents; Physostigmine	1995
Antidotes: benefits and risks. Toxicology letters, 1995, Volume: 82-83 Topics: Acetylcysteine; Animals; Antidotes; Deferoxamine; Flumazenil; Humans; Naloxone	1995
Diagnosis and management of opioid- and benzodiazepine-induced comatose overdose in children. Current opinion in pediatrics, 1996, Volume: 8, Issue:3 Topics: Adolescent; Antidotes; Benzodiazepines; Child; Child, Preschool; Coma; Drug Overdose; Flumazenil; Humans; Infant; Infant, Newborn; Naloxone; Narcotics	1996
Clinical applications of commonly used contemporary antidotes. A US perspective. Drug safety, 1997, Volume: 16, Issue:1 Topics: Acetylcysteine; Antidotes; Antivenins; Atropine; Deferoxamine; Flumazenil; Humans; Hydroxocobalamin; Naloxone; Physostigmine; Poisoning; Succimer	1997
The use of antidotes in the management of central nervous system depression. Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1997, Volume: 19 Topics: Antidotes; Benzodiazepines; Central Nervous System Depressants; Central Nervous System Diseases; Emergency Medicine; Ethanol; Flumazenil; Humans; Naloxone; Narcotic Antagonists; Narcotics	1997
Coma induced by intoxication. Acta neurologica Belgica, 2000, Volume: 100, Issue:4 Topics: Accidental Falls; Alcohol-Induced Disorders, Nervous System; Alcoholic Intoxication; Antidotes; Brain Injuries; Coma; Diabetic Coma; Diagnosis, Differential; Diagnostic Tests, Routine; Drug Overdose; Emergencies; Ethanol; First Aid; Flumazenil; Glucagon; Glucose; Humans; Hypoglycemia; Hypoxia, Brain; Monitoring, Physiologic; Naloxone; Neurologic Examination; Stroke; Thiamine	2000
The coma cocktail: indications, contraindications, adverse effects, proper dose, and proper route. Journal of emergency nursing, 2004, Volume: 30, Issue:6 Topics: Adult; Antidotes; Child; Coma; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Overdose; Drug Therapy, Combination; Flumazenil; Glucose; Humans; Naloxone; Narcotic Antagonists; Oxygen; Poisoning; Suicide, Attempted; Thiamine	2004
Sedation and analgesia for gastrointestinal endoscopy during pregnancy. Gastrointestinal endoscopy clinics of North America, 2006, Volume: 16, Issue:1 Topics: Analgesia; Analgesics, Opioid; Cholangiopancreatography, Endoscopic Retrograde; Conscious Sedation; Diazepam; Endoscopy, Gastrointestinal; Female; Fentanyl; Fetus; Flumazenil; Humans; Hypnotics and Sedatives; Ketamine; Lidocaine; Meperidine; Naloxone; Pregnancy; Propofol; Risk Assessment; Triage	2006
[Drug dependence syndrome as a side effect of medical drug use]. Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8 Topics: Central Nervous System Agents; Clonidine; Flumazenil; Humans; Naloxone; Psychotherapy, Group; Self-Help Groups; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors	2007
Flumazenil, naloxone and the 'coma cocktail'. British journal of clinical pharmacology, 2016, Volume: 81, Issue:3 Topics: Analgesics, Opioid; Antidotes; Benzodiazepines; Coma; Drug Overdose; Flumazenil; Humans; Naloxone	2016
Sedation in the Ambulatory Endoscopy Center: Optimizing Safety, Expectations and Throughput. Gastrointestinal endoscopy clinics of North America, 2016, Volume: 26, Issue:3 Topics: Ambulatory Care Facilities; Analgesics, Opioid; Antidotes; Benzodiazepines; Conscious Sedation; Deep Sedation; Efficiency; Endoscopy, Gastrointestinal; Flumazenil; Humans; Hypnotics and Sedatives; Monitoring, Intraoperative; Naloxone; Narcotic Antagonists; Patient Safety; Propofol	2016
Review of Intranasally Administered Medications for Use in the Emergency Department. The Journal of emergency medicine, 2017, Volume: 53, Issue:1 Topics: Administration, Intranasal; Anesthetics, Dissociative; Anticonvulsants; Antidotes; Antipsychotic Agents; Dexmedetomidine; Emergency Service, Hospital; Fentanyl; Flumazenil; Haloperidol; Humans; Hydromorphone; Hypnotics and Sedatives; Ketamine; Lorazepam; Midazolam; Naloxone; Narcotic Antagonists; Narcotics	2017

Trials

7 trial(s) available for flumazenil and naloxone

Article	Year
Nociceptive quality of the orbicularis oculi reflexes as evaluated by distinct opiate- and benzodiazepine-induced changes in man. Brain research, 1991, Aug-16, Volume: 556, Issue:2 Topics: Adult; Blinking; Diazepam; Electric Stimulation; Electromyography; Fentanyl; Flumazenil; Humans; Naloxone; Nociceptors; Placebos	1991
[Antagonism of flunitrazepam and fentanyl by flumazenil, naloxone or nalbuphine]. Der Anaesthesist, 1990, Volume: 39, Issue:1 Topics: Adult; Double-Blind Method; Fentanyl; Flumazenil; Flunitrazepam; Humans; Middle Aged; Morphinans; Nalbuphine; Naloxone; Randomized Controlled Trials as Topic; Respiratory Insufficiency	1990
Effect of flumazenil on basal and naloxone-stimulated ACTH and cortisol release in humans. Clinical and experimental pharmacology & physiology, 1994, Volume: 21, Issue:2 Topics: Adrenocorticotropic Hormone; Aged; Double-Blind Method; Female; Flumazenil; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Middle Aged; Naloxone; Pituitary-Adrenal System	1994
Ability of flumazenil, butorphanol, and naloxone to reverse the anesthetic effects of oxymorphone-diazepam in dogs. Journal of the American Veterinary Medical Association, 1996, Aug-15, Volume: 209, Issue:4 Topics: Adjuvants, Anesthesia; Anesthetics, Combined; Animals; Butorphanol; Cross-Over Studies; Diazepam; Dogs; Drug Combinations; Female; Flumazenil; Male; Naloxone; Narcotic Antagonists; Oxymorphone; Time Factors	1996
Midazolam-flumazenil versus propofol anaesthesia for scoliosis surgery with wake-up tests. Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:1 Topics: Adolescent; Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Intravenous; Antidotes; Arousal; Child; Drug Costs; Evoked Potentials, Somatosensory; Female; Flumazenil; Humans; Intraoperative Care; Intubation, Intratracheal; Male; Memory; Midazolam; Monitoring, Intraoperative; Naloxone; Narcotic Antagonists; Pain; Postoperative Care; Propofol; Prospective Studies; Psychomotor Performance; Scoliosis; Spinal Cord; Wakefulness	1998
Antagonistic effect of atipamezole, flumazenil and naloxone following anaesthesia with xylazine, tramadol and tiletamine/zolazepam combinations in pigs. Veterinary anaesthesia and analgesia, 2011, Volume: 38, Issue:4 Topics: Adrenergic alpha-2 Receptor Antagonists; Anesthesia Recovery Period; Anesthetics; Animals; Cross-Over Studies; Drug Antagonism; Drug Combinations; Female; Flumazenil; GABA Modulators; Imidazoles; Male; Naloxone; Narcotic Antagonists; Prospective Studies; Swine; Tiletamine; Tramadol; Xylazine; Zolazepam	2011
Injection anaesthesia with fentanyl-midazolam-medetomidine in adult female mice: importance of antagonization and perioperative care. Laboratory animals, 2016, Volume: 50, Issue:4 Topics: Analgesics; Anesthetics, Combined; Animals; Body Temperature; Female; Fentanyl; Flumazenil; Heart Rate; Imidazoles; Injections, Intraperitoneal; Medetomidine; Mice; Mice, Inbred C57BL; Midazolam; Naloxone; Narcotic Antagonists; Neurotransmitter Agents; Perioperative Care	2016

Other Studies

96 other study(ies) available for flumazenil and naloxone

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Opioid receptor mediation of the hypothermic response to caffeine. European journal of pharmacology, 1992, Dec-02, Volume: 224, Issue:2-3 Topics: Animals; Body Temperature; Caffeine; Dose-Response Relationship, Drug; Drug Interactions; Flumazenil; Male; Metergoline; Mice; Naloxone; Receptors, Opioid; Sympatholytics	1992
Pharmacological dissociation between the spatial learning deficits produced by morphine and diazepam. Psychopharmacology, 1992, Volume: 108, Issue:1-2 Topics: Animals; Cues; Diazepam; Flumazenil; Learning; Male; Morphine; Naloxone; Rats; Space Perception	1992
The effects of centrally acting drugs on the EEG correlates of meditation. Biofeedback and self-regulation, 1992, Volume: 17, Issue:3 Topics: Adult; Computers; Diazepam; Electroencephalography; Flumazenil; Humans; Male; Naloxone; Relaxation Therapy	1992
Relative effects of intrathecal administration of fentanyl and midazolam on A delta and C fibre reflexes. Neuropharmacology, 1992, Volume: 31, Issue:5 Topics: Anesthesia, Spinal; Animals; Dogs; Electric Stimulation; Fentanyl; Flumazenil; Kidney; Midazolam; Naloxone; Nerve Fibers; Nerve Fibers, Myelinated; Reflex; Sympathetic Nervous System; Tibial Nerve	1992
Reversal by naloxone of spinal antinociceptive effects of fentanyl, ketocyclazocine and midazolam. European journal of anaesthesiology, 1991, Volume: 8, Issue:5 Topics: Analgesia, Epidural; Animals; Catheters, Indwelling; Dose-Response Relationship, Drug; Drug Tolerance; Electric Stimulation; Ethylketocyclazocine; Fentanyl; Flumazenil; Injections, Spinal; Lumbar Vertebrae; Male; Midazolam; Naloxone; Nociceptors; Pain; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Opioid; Sensory Thresholds	1991
Spinally mediated antinociception following intrathecal chlordiazepoxide--further evidence for a benzodiazepine spinal analgesic effect. European journal of anaesthesiology, 1991, Volume: 8, Issue:5 Topics: Analgesia, Epidural; Animals; Catheters, Indwelling; Chlordiazepoxide; Dose-Response Relationship, Drug; Electric Stimulation; Fentanyl; Flumazenil; Injections, Spinal; Male; Naloxone; Nociceptors; Pain; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sensory Thresholds	1991
Physostigmine is equipotent to flumazenil only in excessive doses, while naloxone is ineffective in reversing midazolam anesthesia. Middle East journal of anaesthesiology, 1991, Volume: 11, Issue:3 Topics: Animals; Flumazenil; Male; Midazolam; Naloxone; Physostigmine; Rats; Rats, Inbred Strains	1991
Effects of forced shaking stress at low temperature on pentobarbital-induced sleeping in mice. General pharmacology, 1991, Volume: 22, Issue:4 Topics: Animals; Cold Temperature; Diazepam; Drug Resistance; Flumazenil; Male; Mice; Naloxone; Nociceptors; Pentobarbital; Sleep; Stress, Physiological	1991
Respiratory and locomotor stimulation by low doses of dermorphin, a mu1 receptor-mediated effect. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:1 Topics: Analgesics, Opioid; Animals; Flumazenil; Male; Motor Activity; Naloxone; Oligopeptides; Opioid Peptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Respiration	1990
Time-dependent melatonin analgesia in mice: inhibition by opiate or benzodiazepine antagonism. European journal of pharmacology, 1991, Feb-26, Volume: 194, Issue:1 Topics: Analgesics; Animals; Benzodiazepines; Circadian Rhythm; Flumazenil; Kinetics; Light; Male; Melatonin; Mice; Naloxone; Narcotic Antagonists; Pain Measurement; Reaction Time; Time Factors	1991
Using antagonists to assess neurochemical coding of a drug's ability to establish a conditioned place preference. Pharmacology, biochemistry, and behavior, 1990, Volume: 37, Issue:3 Topics: Analgesics; Animals; Brain Chemistry; Conditioning, Operant; Flumazenil; Habituation, Psychophysiologic; Male; Morphine; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Scopolamine	1990
Benzodiazepines and their antagonists interfere with opioid-dependent stress-induced analgesia. Pharmacology, biochemistry, and behavior, 1990, Volume: 36, Issue:1 Topics: Analgesia; Animals; Benzodiazepines; Drug Interactions; Electroshock; Flumazenil; In Vitro Techniques; Male; Mesencephalon; Naloxone; Pain; Pyrazoles; Rats; Rats, Inbred Strains; Sensory Thresholds; Stress, Physiological	1990
Interaction of midazolam and morphine in the spinal cord of the rat. Neuropharmacology, 1990, Volume: 29, Issue:4 Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Interactions; Electromyography; Flumazenil; Injections, Spinal; Male; Midazolam; Morphine; Naloxone; Rats; Rats, Inbred Strains; Reaction Time; Receptors, GABA-A; Spinal Cord	1990
Anesthetic interactions of midazolam and fentanyl: is there acute tolerance to the opioid? Anesthesiology, 1989, Volume: 70, Issue:4 Topics: Anesthesia, Inhalation; Animals; Dogs; Drug Interactions; Enflurane; Fentanyl; Flumazenil; Male; Midazolam; Naloxone; Pulmonary Alveoli; Respiration	1989
Naloxone-induced analgesia: effects of the benzodiazepine antagonist Ro 15-1788. Pharmacology, biochemistry, and behavior, 1989, Volume: 34, Issue:1 Topics: Analgesia; Animals; Drug Interactions; Flumazenil; Male; Naloxone; Pain; Rats; Rats, Inbred Strains; Sensory Thresholds; Stress, Physiological	1989
Population differences in benzodiazepine sensitive male scent-induced analgesia in the deer mouse, Peromyscus maniculatus. Pharmacology, biochemistry, and behavior, 1989, Volume: 32, Issue:3 Topics: Analgesia; Animals; Central Nervous System; Diazepam; Flumazenil; Male; Mice; Naloxone; Olfactory Pathways; Peromyscus; Receptors, GABA-A; Receptors, Opioid	1989
Male scent-induced analgesia in the deer mouse, Peromyscus maniculatus: involvement of benzodiazepine systems. Physiology & behavior, 1988, Volume: 42, Issue:2 Topics: Aggression; Analgesia; Animals; Diazepam; Female; Flumazenil; Male; Naloxone; Nociceptors; Peromyscus; Receptors, GABA-A; Smell	1988
Benzodiazepine antagonist Ro 15-1788 in self-poisoning. Diagnostic and therapeutic use. Archives of internal medicine, 1985, Volume: 145, Issue:4 Topics: Adult; Aged; Anti-Anxiety Agents; Antidotes; Benzodiazepinones; Coma; Diazepam; Electroencephalography; Female; Flumazenil; Flunitrazepam; Humans; Male; Middle Aged; Naloxone; Suicide, Attempted	1985
Reversal of antinociceptive effect of cholecystokinin by benzodiazepines and a benzodiazepine antagonist, Ro 15-1788. Japanese journal of pharmacology, 1985, Volume: 37, Issue:1 Topics: Analgesics; Animals; Anti-Anxiety Agents; Benzodiazepinones; Chlordiazepoxide; Cholecystokinin; Diazepam; Flumazenil; Flurazepam; Male; Mice; Morphine; Naloxone; Pain; Sensory Thresholds; Time Factors	1985
Inhibition of hypothermic effect of cholecystokinin by benzodiazepines and a benzodiazepine antagonist, Ro 15-1788, in mice. Japanese journal of pharmacology, 1985, Volume: 39, Issue:2 Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Body Temperature; Cholecystokinin; Flumazenil; Injections, Intraperitoneal; Male; Mice; Naloxone; Proglumide; Time Factors	1985
Antagonism of dermorphin-induced catalepsy with naloxone, TRH-analog CG3703 and the benzodiazepine antagonist, Ro 15-1788. Neuropharmacology, 1988, Volume: 27, Issue:10 Topics: Alprazolam; Analgesics, Opioid; Animals; Catalepsy; Flumazenil; Injections, Intraventricular; Male; Naloxone; Oligopeptides; Opioid Peptides; Rats; Rats, Inbred Strains; Thyrotropin-Releasing Hormone	1988
Effects of tifluadom on food consumption compared with chlordiazepoxide and kappa agonists in the rat. Neuropharmacology, 1985, Volume: 24, Issue:9 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzodiazepines; Benzodiazepinones; Benzomorphans; Chlordiazepoxide; Convulsants; Cyclazocine; Drug Interactions; Eating; Ethylketocyclazocine; Flumazenil; Male; Naloxone; Pyrazoles; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa	1985
The benzodiazepine (+)-tifluadom (KC-6128), but not its optical isomer (KC-5911) induces opioid kappa receptor-related EEG power spectra and evoked potential changes. Pharmacology, 1986, Volume: 33, Issue:5 Topics: Animals; Benzodiazepines; Benzomorphans; Dogs; Electroencephalography; Evoked Potentials; Flumazenil; Naloxone; Receptors, Opioid; Receptors, Opioid, kappa; Stereoisomerism	1986
Naloxone-sensitive and GABAA receptor mediated analgesic response of benzodiazepines in mice. Methods and findings in experimental and clinical pharmacology, 1987, Volume: 9, Issue:2 Topics: Analgesics; Animals; Benzodiazepines; Benzodiazepinones; Bicuculline; Female; Flumazenil; Male; Mice; Naloxone; Phenytoin; Reaction Time; Receptors, GABA-A	1987
Reversal of the effects of centrally-administered morphine on colonic motility in dogs by the benzodiazepine receptor antagonist RO 15-1788. Life sciences, 1987, Sep-21, Volume: 41, Issue:12 Topics: Animals; Colon; Dogs; Flumazenil; Gastrointestinal Motility; Injections, Intraventricular; Morphine; Naloxone; Receptors, GABA-A	1987
[Tifluadom, a benzodiazepine with opioid-like activity: study of its central mechanism of action in conscious dogs]. EEG-EMG Zeitschrift fur Elektroenzephalographie, Elektromyographie und verwandte Gebiete, 1986, Volume: 17, Issue:1 Topics: Animals; Benzodiazepines; Benzodiazepinones; Benzomorphans; Brain; Dogs; Dose-Response Relationship, Drug; Electroencephalography; Evoked Potentials, Somatosensory; Flumazenil; Naloxone	1986
Characterization of the analgesic effects of the benzodiazepine antagonist, Ro 15-1788. Brain research, 1987, Jul-14, Volume: 415, Issue:2 Topics: Analgesics; Animals; Diazepam; Flumazenil; Male; Naloxone; Rats; Rats, Inbred Strains	1987
Analgesic effects of the progesterone metabolite, 3 alpha-hydroxy-5 alpha-pregnan-20-one, and possible modes of action in mice. Brain research, 1987, Jul-14, Volume: 415, Issue:2 Topics: Analgesics; Animals; Bicuculline; Brain; Calcium Channel Blockers; Flumazenil; Injections, Intraventricular; Male; Mice; Naloxone; Picrotoxin; Progesterone	1987
RO 15-1788 produces naloxone-reversible analgesia in the rat. European journal of pharmacology, 1988, Jan-27, Volume: 146, Issue:1 Topics: Analgesics; Animals; Flumazenil; Injections, Intraperitoneal; Injections, Intraventricular; Male; Midazolam; Naloxone; Pain; Rats	1988
Brief exposure to a natural predator, the short-tailed weasel, induces benzodiazepine-sensitive analgesia in white-footed mice. Physiology & behavior, 1988, Volume: 43, Issue:2 Topics: Analgesia; Animals; Appetitive Behavior; Diazepam; Flumazenil; Handling, Psychological; Hot Temperature; Male; Naloxone; Pain; Peromyscus; Predatory Behavior; Rabbits; Reference Values; Rodentia	1988
Analgesic effects of the putative FSH-suppressing gonadal steroid, 3 alpha-hydroxy-4-pregnen-20-one: possible modes of action. Brain research, 1988, Sep-27, Volume: 461, Issue:1 Topics: 20-alpha-Dihydroprogesterone; Analgesia; Analgesics; Animals; Bicuculline; Calcium Channel Blockers; Cerebral Ventricles; Flumazenil; Follicle Stimulating Hormone; Injections, Intraventricular; Male; Mice; Naloxone; Progesterone; Reference Values	1988
Reversal of the antinociceptive effects of centrally-administered morphine by the benzodiazepine receptor antagonist Ro 15-1788. Life sciences, 1984, Dec-24, Volume: 35, Issue:26 Topics: Animals; Benzodiazepinones; Dose-Response Relationship, Drug; Flumazenil; GABA-A Receptor Antagonists; Male; Mice; Morphine; Naloxone; Saimiri	1984
The role of opioid receptor sub-types in tifluadom-induced feeding. The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:10 Topics: Animals; Benzodiazepines; Benzodiazepinones; Benzomorphans; Convulsants; Eating; Enkephalin, Leucine; Flumazenil; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Stereoisomerism	1984
Self-injection of diazepam in naive rats: effects of dose, schedule and blockade of different receptors. Psychopharmacology, 1984, Volume: 84, Issue:2 Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Bicuculline; Diazepam; Dose-Response Relationship, Drug; Extinction, Psychological; Flumazenil; Haloperidol; Male; Naloxone; Rats; Receptors, Drug; Reinforcement Schedule; Self Administration	1984
Comparison of five preanesthetic medicaments in thiopental-anesthetized cats: antagonism by selected compounds. American journal of veterinary research, 1984, Volume: 45, Issue:11 Topics: 4-Aminopyridine; Acepromazine; Aminopyridines; Anesthesia, General; Animals; Arousal; Benzodiazepinones; Cats; Central Nervous System Stimulants; Convulsants; Diazepam; Drug Antagonism; Female; Flumazenil; Ketamine; Male; Meperidine; Naloxone; Pentobarbital; Preanesthetic Medication; Sodium Chloride; Xylazine; Yohimbine	1984
Decreased predator avoidance in parasitized mice: neuromodulatory correlates. Parasitology, 1995, Volume: 111 ( Pt 3) Topics: Animals; Anxiety; Avoidance Learning; Bicuculline; Cats; Coccidiosis; Dizocilpine Maleate; Eimeria; Flumazenil; GABA Antagonists; GABA-A Receptor Antagonists; Male; Mice; N-Methylaspartate; Naloxone; Odorants; Picrotoxin; Predatory Behavior; Receptors, GABA-A	1995
Effects of intravenous anesthetics on phosphatidylinositol turnover in rat cerebral cortical prisms. Anesthesia and analgesia, 1994, Volume: 79, Issue:2 Topics: Anesthetics, Intravenous; Animals; Cerebral Cortex; Diazepam; Dose-Response Relationship, Drug; Droperidol; Fentanyl; Flumazenil; Inositol Phosphates; Ketamine; Male; Naloxone; Norepinephrine; Phosphatidylinositols; Prazosin; Rats; Rats, Wistar; Thiamylal	1994
Mechanisms of the influence of midazolam on morphine antinociception at spinal and supraspinal levels in rats. European journal of pharmacology, 1994, Dec-27, Volume: 271, Issue:2-3 Topics: Analgesia; Animals; Drug Interactions; Flumazenil; Injections, Intraventricular; Male; Midazolam; Morphine; Naloxone; Rats; Rats, Sprague-Dawley; Reaction Time; Spinal Cord	1994
Diazepam attenuates hyperexcitability and mechanical hypersensitivity of dorsal horn convergent neurones during reperfusion of the rat's tail following ischaemia. Brain research, 1994, Oct-03, Volume: 659, Issue:1-2 Topics: Animals; Diazepam; Electrophysiology; Flumazenil; Ischemia; Male; Naloxone; Neurons; Physical Stimulation; Rats; Rats, Sprague-Dawley; Reperfusion; Spinal Cord; Tail	1994
Effects of midazolam and naloxone in rats tested for sensitivity/reactivity to formalin pain in a familiar, novel or aversively conditioned environment. Psychopharmacology, 1994, Volume: 115, Issue:1-2 Topics: Analgesia; Animals; Conditioning, Operant; Conditioning, Psychological; Environment; Extinction, Psychological; Flumazenil; Formaldehyde; Male; Midazolam; Naloxone; Pain Measurement; Rats; Rats, Wistar; Reaction Time; Reinforcement, Psychology	1994
Low and high doses of midazolam differentially affect hypoalgesia in rats conditioned to a heat stressor. Psychopharmacology, 1993, Volume: 111, Issue:1 Topics: Analgesia; Animals; Behavior, Animal; Conditioning, Psychological; Dose-Response Relationship, Drug; Fear; Flumazenil; Hot Temperature; Male; Midazolam; Naloxone; Pain Measurement; Rats; Rats, Wistar; Stress, Psychological	1993
Ejaculation induced changes in escape latency in the hot plate test: pharmacological analysis of anxiolytic versus analgesic effect. Behavioural brain research, 1994, Feb-28, Volume: 60, Issue:2 Topics: Animals; Arousal; Copulation; Diazepam; Ejaculation; Escape Reaction; Female; Flumazenil; Habituation, Psychophysiologic; Male; Morphine; Naloxone; Pain Threshold; Rats; Rats, Wistar; Reaction Time; Thermosensing; Vocalization, Animal	1994
The value of acute medical services sited adjacent to areas of high drug-injecting activity. Addiction (Abingdon, England), 1994, Volume: 89, Issue:6 Topics: Adult; Female; Flumazenil; Health Services; Humans; Illicit Drugs; Naloxone; Sex Factors; Sex Work; Substance Abuse, Intravenous; United Kingdom	1994
Respiratory mu-opioid and benzodiazepine interactions in the unrestrained rat. Neuropharmacology, 1993, Volume: 32, Issue:4 Topics: Alprazolam; Analgesics, Opioid; Animals; Benzodiazepines; Dose-Response Relationship, Drug; Flumazenil; Injections, Intraventricular; Male; Naloxone; Oligopeptides; Opioid Peptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Respiration; Respiratory System	1993
Attenuation of reperfusion hyperalgesia in the rat by systemic administration of benzodiazepines. British journal of pharmacology, 1993, Volume: 110, Issue:3 Topics: Animals; Behavior, Animal; Benzodiazepines; Chlordiazepoxide; Depression, Chemical; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Hyperalgesia; Ischemia; Male; Motor Activity; Naloxone; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Reperfusion Injury; Tail	1993
The relative efficacy of antidotes. Journal of toxicology. Clinical toxicology, 1995, Volume: 33, Issue:6 Topics: Antidotes; Atropine; Chelating Agents; Diazepam; Flumazenil; Humans; Naloxone; Poisoning	1995
Cannabinoid modulation of rat pup ultrasonic vocalizations. European journal of pharmacology, 1996, Oct-10, Volume: 313, Issue:1-2 Topics: Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Benzazepines; Body Temperature; Cannabinoids; Cyclohexanols; Dopamine Antagonists; Dose-Response Relationship, Drug; Flumazenil; GABA Modulators; Hypothermia; Motor Activity; Naloxone; Narcotic Antagonists; Piperidines; Pyrazoles; Rats; Rimonabant; Vocalization, Animal	1996
Transient emotional changes elicited by intraperitoneal saline injection: effect of naloxone and flumazenil. Pharmacology, biochemistry, and behavior, 1997, Volume: 56, Issue:2 Topics: Animals; Fear; Flumazenil; GABA-A Receptor Antagonists; Injections, Intraperitoneal; Male; Motor Activity; Naloxone; Narcotic Antagonists; Rats; Rats, Wistar; Sodium Chloride; Stress, Psychological	1997
Midazolam-induced rapid changes in licking behaviour: evidence for involvement of endogenous opioid peptides. Psychopharmacology, 1997, Volume: 131, Issue:3 Topics: Animals; Drug Interactions; Feeding Behavior; Flumazenil; Male; Midazolam; Naloxone; Opioid Peptides; Rats	1997
The anxiolytic effect of gamma-hydroxybutyrate in the elevated plus maze is reversed by the benzodiazepine receptor antagonist, flumazenil. European journal of pharmacology, 1998, Jan-19, Volume: 342, Issue:1 Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Benzocycloheptenes; Diazepam; Dose-Response Relationship, Drug; Flumazenil; GABA Modulators; Male; Motor Activity; Naloxone; Narcotic Antagonists; Rats; Sodium Oxybate	1998
[The effects of flumazenil or bicuculline on the respiratory depression by morphine]. Masui. The Japanese journal of anesthesiology, 1998, Volume: 47, Issue:4 Topics: Action Potentials; Animals; Bicuculline; Depression, Chemical; Flumazenil; GABA Antagonists; GABA Modulators; Morphine; Naloxone; Narcotic Antagonists; Phrenic Nerve; Rats; Respiration; Respiratory Insufficiency	1998
Supraspinal flumazenil inhibits the antianalgesic action of spinal dynorphin A (1-17). Pharmacology, biochemistry, and behavior, 1998, Volume: 60, Issue:1 Topics: Analgesia; Analgesics; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Dynorphins; Flumazenil; GABA Agonists; GABA-A Receptor Agonists; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Naltrexone; Physostigmine	1998
[Transitory comatose situation secondary to an infarction of the posterior circulation, reversed by naloxone?]. Revista de neurologia, 1998, Volume: 26, Issue:154 Topics: Adult; Brain Ischemia; Cerebral Infarction; Coma; Drug Therapy, Combination; Emergency Medical Services; Female; Flumazenil; GABA Modulators; Glucose; Humans; Hypertonic Solutions; Naloxone; Narcotic Antagonists; Thiamine; Vasodilator Agents	1998
[Effects of anesthetics on somatosensory evoked potentials by median nerve stimulation in human--analyses after single administration in volunteers]. Masui. The Japanese journal of anesthesiology, 1998, Volume: 47, Issue:8 Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Electric Stimulation; Evoked Potentials, Somatosensory; Flumazenil; Humans; Male; Median Nerve; Midazolam; Naloxone; Nitrous Oxide; Propofol; Reaction Time; Thiopental	1998
[Persisting respiratory depression following intrathecal administration of morphine and simultaneous sedation with midazolam]. Der Anaesthesist, 1999, Volume: 48, Issue:9 Topics: Aged; Analgesics, Opioid; Flumazenil; Humans; Hypnotics and Sedatives; Injections, Spinal; Intubation, Intratracheal; Male; Midazolam; Morphine; Naloxone; Narcotic Antagonists; Respiration, Artificial; Respiratory Insufficiency	1999
Naloxone blocks 'anxiolytic' effects of neuropeptide Y. Peptides, 2001, Volume: 22, Issue:4 Topics: Animals; Anti-Anxiety Agents; Chlordiazepoxide; Conflict, Psychological; Dose-Response Relationship, Drug; Flumazenil; Male; Naloxone; Narcotic Antagonists; Neuropeptide Y; Rats; Rats, Wistar	2001
Interactions between LY354740, a group II metabotropic agonist and the GABA(A)-benzodiazepine receptor complex in the rat elevated plus-maze. Journal of psychopharmacology (Oxford, England), 2001, Volume: 15, Issue:2 Topics: Animals; Anti-Anxiety Agents; Anxiety; Bridged Bicyclo Compounds; Chlordiazepoxide; Dose-Response Relationship, Drug; Exploratory Behavior; Flumazenil; GABA Modulators; Male; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Metabotropic Glutamate	2001
Influence of different neural systems on the secretion of sex hormones in potassium deficient mice. Life sciences, 2002, Aug-16, Volume: 71, Issue:13 Topics: Animals; Drug Therapy, Combination; Estradiol; Estrous Cycle; Female; Flumazenil; GABA Modulators; Gonadotropin-Releasing Hormone; Hypokalemia; Hypothalamus; Luteinizing Hormone; Mice; Naloxone; Narcotic Antagonists; Neurotransmitter Agents; Norepinephrine; Potassium Deficiency; Synaptic Transmission; Testosterone	2002
Cardiorespiratory effects of medetomidine-butorphanol, medetomidine-butorphanol-diazepam, and medetomidine-butorphanol-ketamine in captive red wolves (Canis rufus). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2002, Volume: 33, Issue:2 Topics: Adrenergic alpha-Antagonists; Anesthetics, Dissociative; Animals; Animals, Zoo; Blood Pressure; Body Temperature; Butorphanol; Diazepam; Drug Combinations; Female; Flumazenil; GABA Modulators; Heart Rate; Hypertension; Hypnotics and Sedatives; Imidazoles; Immobilization; Ketamine; Male; Medetomidine; Muscle Relaxation; Naloxone; Narcotic Antagonists; Narcotics; Respiration; Wolves	2002
No more coma cocktails. Using science to dispel myths & improve patient care. JEMS : a journal of emergency medical services, 2002, Volume: 27, Issue:11 Topics: Coma; Drug Combinations; Emergency Medical Services; Evidence-Based Medicine; Flumazenil; GABA Modulators; Glucose; Humans; Hypoglycemia; Naloxone; Narcotic Antagonists; Quality Assurance, Health Care; Thiamine; United States	2002
A near-fatal overdose of carisoprodol (SOMA): case report. Journal of toxicology. Clinical toxicology, 2004, Volume: 42, Issue:2 Topics: Adult; Antidotes; Carisoprodol; Charcoal; Chlordiazepoxide; Clindamycin; Drug Overdose; Drug Therapy, Combination; Flumazenil; Gastric Lavage; Humans; Male; Muscle Relaxants, Central; Naloxone; Sodium Bicarbonate; Sorbitol; Temazepam; Treatment Outcome	2004
Benzodiazepine receptor-dependent modulation of neutrophil (PMN) free amino- and alpha-keto acid profiles or immune functions. Amino acids, 2005, Volume: 28, Issue:1 Topics: Adult; Amino Acids; Benzodiazepinones; Cells, Cultured; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Humans; Hydrogen Peroxide; Isoquinolines; Keto Acids; Male; Midazolam; Naloxone; Neutrophils; Peroxidase; Receptors, GABA-A; Superoxides	2005
Unplanned 'unconsciousness' at Caesarean section: hysteria or drug reaction? International journal of obstetric anesthesia, 2007, Volume: 16, Issue:2 Topics: Adult; Amides; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthetics, Intravenous; Anesthetics, Local; Antidotes; Blood Pressure; Central Nervous System Stimulants; Cesarean Section; Diagnosis, Differential; Elective Surgical Procedures; Ephedrine; Female; Flumazenil; Humans; Hysteria; Meperidine; Midazolam; Naloxone; Narcotic Antagonists; Pregnancy; Ropivacaine; Unconsciousness	2007
Drug challenges reveal differences in mediation of stress facilitation of voluntary alcohol drinking and withdrawal-induced anxiety in alcohol-preferring P rats. Alcoholism, clinical and experimental research, 2007, Volume: 31, Issue:9 Topics: Alcohol Drinking; Aminopyridines; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Benzodiazepines; Buspirone; Dopamine Antagonists; Ethanol; Flumazenil; GABA Modulators; Haloperidol; Indoles; Naloxone; Narcotic Antagonists; Olanzapine; Rats; Rats, Inbred Strains; Restraint, Physical; Serotonin Receptor Agonists; Stress, Physiological; Substance Withdrawal Syndrome	2007
Anticonvulsant effects of aerial parts of Passiflora incarnata extract in mice: involvement of benzodiazepine and opioid receptors. BMC complementary and alternative medicine, 2007, Aug-08, Volume: 7 Topics: Animals; Anticonvulsants; Antidotes; Convulsants; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy, Absence; Flumazenil; Injections, Intraperitoneal; Male; Mice; Mice, Inbred BALB C; Naloxone; Narcotic Antagonists; Passiflora; Pentylenetetrazole; Phytotherapy; Plant Components, Aerial; Plant Extracts; Receptors, GABA-A; Receptors, Opioid; Sodium Chloride; Treatment Outcome	2007
Effect of withdrawal of diazepam or morphine treatment on gastric motility (charcoal meal test) in mice: possible role of different central and peripheral receptors. Indian journal of experimental biology, 2007, Volume: 45, Issue:7 Topics: Analgesics; Analgesics, Opioid; Animals; Central Nervous System; Chemistry, Pharmaceutical; Diazepam; Drug Evaluation, Preclinical; Flumazenil; Gastric Mucosa; Male; Mice; Morphine; Naloxone; Peripheral Nervous System; Stomach; Substance Withdrawal Syndrome	2007
Acute poisonings treated in hospitals in Oslo: a one-year prospective study (II): clinical outcome. Clinical toxicology (Philadelphia, Pa.), 2008, Volume: 46, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidotes; Coma; Cross-Sectional Studies; Ethanol; Female; Flumazenil; Hospital Mortality; Hospitalization; Humans; Illicit Drugs; Male; Middle Aged; Naloxone; Norway; Poisoning; Prospective Studies; Severity of Illness Index; Treatment Outcome	2008
Anticonvulsant activity of Carissa edulis (Vahl) (Apocynaceae) root bark extract. Journal of ethnopharmacology, 2008, Nov-20, Volume: 120, Issue:2 Topics: Administration, Oral; Animals; Anticonvulsants; Apocynaceae; Chickens; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Flumazenil; Injections, Intraperitoneal; Lethal Dose 50; Male; Mice; Naloxone; Phenytoin; Plant Bark; Plant Extracts; Plant Roots; Seizures; Toxicity Tests, Acute	2008
Reduced midazolam clearance must be considered in prolonged coma. Anaesthesia and intensive care, 2008, Volume: 36, Issue:6 Topics: Adult; Anesthetics, Intravenous; Antidotes; Cholinesterase Inhibitors; Coma; Flumazenil; Humans; Male; Metabolic Clearance Rate; Midazolam; Naloxone; Narcotic Antagonists; Physostigmine; Time	2008
The antinociceptive effects and pharmacological properties of JM-1232(-): a novel isoindoline derivative. Anesthesia and analgesia, 2009, Volume: 108, Issue:3 Topics: Acetic Acid; Analgesics; Animals; Dose-Response Relationship, Drug; Flumazenil; GABA Modulators; Hot Temperature; Hypnotics and Sedatives; Isoindoles; Male; Mice; Motor Activity; Naloxone; Narcotic Antagonists; Pain Measurement; Physical Stimulation; Piperazines; Pressure; Reaction Time	2009
Intranasal flumazenil and naloxone to reverse over-sedation in a child undergoing dental restorations. Paediatric anaesthesia, 2009, Volume: 19, Issue:8 Topics: Adjuvants, Anesthesia; Administration, Intranasal; Anesthesia, Dental; Antidotes; Child, Preschool; Dental Restoration, Temporary; Female; Flumazenil; Humans; Laryngismus; Midazolam; Naloxone; Narcotic Antagonists; Oxygen; Sufentanil; Treatment Outcome	2009
Cardiovascular responses to intravenous injection of a novel isoindolin-1-one derivate in conscious rats. Brain research, 2009, Dec-01, Volume: 1300 Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Atropine; Baroreflex; Blood Pressure; Catecholamines; Catheters, Indwelling; Dose-Response Relationship, Drug; Flumazenil; GABA Modulators; Heart Conduction System; Heart Rate; Isoindoles; Male; Naloxone; Narcotic Antagonists; Parasympatholytics; Piperazines; Propranolol; Rats; Rats, Wistar; Sinoatrial Node; Sympathetic Nervous System; Time Factors	2009
Intranasal flumazenil and naloxone to reverse over-sedation in a child undergoing dental restorations: comment. Paediatric anaesthesia, 2010, Volume: 20, Issue:1 Topics: Administration, Intranasal; Antidotes; Child; Child Behavior; Conscious Sedation; Deep Sedation; Dental Restoration, Permanent; Flumazenil; Humans; Hypnotics and Sedatives; Midazolam; Naloxone; Narcotic Antagonists	2010
Prospective comparative assessment of buprenorphine overdose with heroin and methadone: clinical characteristics and response to antidotal treatment. Journal of substance abuse treatment, 2010, Volume: 38, Issue:4 Topics: Adult; Antidotes; Buprenorphine; Drug Overdose; Female; Flumazenil; Heroin; Heroin Dependence; Humans; Intensive Care Units; Male; Methadone; Middle Aged; Naloxone; Narcotic Antagonists; Narcotics; Prospective Studies; Suicide, Attempted	2010
[Transient decerebrate rigidity from hypoxemia during administration of propofol, midazolam-flumazenil, and remifentanil-naloxone]. Revista espanola de anestesiologia y reanimacion, 2010, Volume: 57, Issue:2 Topics: Airway Obstruction; Anesthetics, Intravenous; Bradycardia; Cardiotonic Agents; Cholangiopancreatography, Endoscopic Retrograde; Choledocholithiasis; Decerebrate State; Flumazenil; GABA Agonists; Humans; Hypnotics and Sedatives; Hypoxia; Intraoperative Complications; Intubation, Intratracheal; Male; Midazolam; Middle Aged; Naloxone; Piperidines; Propofol; Remifentanil; Sleep Apnea, Obstructive	2010
Ability to reverse deeper levels of unintended sedation. Digestion, 2010, Volume: 82, Issue:2 Topics: Analgesics, Opioid; Benzodiazepines; Conscious Sedation; Deep Sedation; Endoscopy, Gastrointestinal; Flumazenil; Humans; Naloxone	2010
Effects of a novel benzodiazepine derivative, JM-1232(-), on human gastroepiploic artery in vitro. Journal of cardiothoracic and vascular anesthesia, 2011, Volume: 25, Issue:1 Topics: Dose-Response Relationship, Drug; Endothelium, Vascular; Flumazenil; GABA Modulators; Gastroepiploic Artery; Humans; In Vitro Techniques; Isoindoles; Midazolam; Muscle Contraction; Muscle, Smooth, Vascular; Naloxone; Narcotic Antagonists; Norepinephrine; Piperazines; Potassium; Propofol; Structure-Activity Relationship; Vasoconstrictor Agents	2011
Short answer question case series: the perils of urine toxicology testing. Emergency medicine journal : EMJ, 2011, Volume: 28, Issue:11 Topics: Adult; Analgesics, Opioid; Antidotes; Flumazenil; Humans; Hypnotics and Sedatives; Male; Naloxone; Narcotic Antagonists; Substance Abuse Detection; Substance-Related Disorders; Toxicity Tests; Urine	2011
Neuropharmacological profile of aqueous extract of Anaphe venata larva (Notondotidae) in rats. African journal of traditional, complementary, and alternative medicines : AJTCAM, 2011, Volume: 8, Issue:3 Topics: Amphetamine; Animals; Ataxia; Behavior, Animal; Dose-Response Relationship, Drug; Flumazenil; Grooming; Injections, Intraperitoneal; Larva; Locomotion; Moths; Naloxone; Neuropharmacology; Neurotransmitter Agents; Rats; Scopolamine; Stereotyped Behavior; Thiamine; Water	2011
Effects of chronic mild stress on the development of drug dependence in rats. Behavioural pharmacology, 2014, Volume: 25, Issue:5-6 Topics: Animals; Chronic Disease; Citalopram; Depressive Disorder; Diazepam; Disease Models, Animal; Flumazenil; GABA Modulators; Male; Mecamylamine; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Stress, Psychological; Substance Withdrawal Syndrome; Substance-Related Disorders	2014
[Hemoperfusion with activated charcoal on valproic acid poisoning. A case report]. Medicina intensiva, 2015, Volume: 39, Issue:7 Topics: Benzodiazepines; Charcoal; Combined Modality Therapy; Depressive Disorder; Drug Overdose; Female; Flumazenil; Hemoperfusion; Humans; Hyperammonemia; Middle Aged; Naloxone; Olanzapine; Paranoid Disorders; Psychotropic Drugs; Respiration, Artificial; Suicide, Attempted; Valproic Acid	2015
Risk Factors and Outcomes of Reversal Agent Use in Moderate Sedation During Endoscopy and Colonoscopy. Journal of clinical gastroenterology, 2016, Volume: 50, Issue:3 Topics: Age Factors; Anti-Arrhythmia Agents; Antidotes; Atropine; Body Mass Index; Bradycardia; Case-Control Studies; Colonoscopy; Conscious Sedation; Female; Fentanyl; Flumazenil; Health Status; Humans; Hypnotics and Sedatives; Hypotension; Hypoxia; Male; Midazolam; Middle Aged; Naloxone; Narcotic Antagonists; Sex Factors; Treatment Outcome	2016
Anticonvulsant Activity of Hydroalcoholic Extract of Citrullus colocynthis Fruit: Involvement of Benzodiazepine and Opioid Receptors. Journal of evidence-based complementary & alternative medicine, 2016, Volume: 21, Issue:4 Topics: Animals; Anticonvulsants; Benzodiazepines; Citrullus colocynthis; Flavonoids; Flumazenil; Fruit; Herb-Drug Interactions; Male; Medicine, Arabic; Mice; Naloxone; Pentylenetetrazole; Plant Extracts; Receptors, Opioid; Seizures	2016
Neurobiological mechanisms of antiallodynic effect of transcranial direct current stimulation (tDCS) in a mice model of neuropathic pain. Brain research, 2018, 03-01, Volume: 1682 Topics: Adenosine A1 Receptor Antagonists; Animals; Caffeine; Central Nervous System Stimulants; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Flumazenil; GABA Modulators; Hyperalgesia; Male; Mice; Morpholines; Naloxone; Narcotic Antagonists; Neuralgia; Pain Threshold; Physical Stimulation; Pyrazoles; Transcranial Direct Current Stimulation; Xanthines	2018
Analysis of medication-related triggers to determine adverse drug events. European journal of hospital pharmacy : science and practice, 2023, Volume: 30, Issue:2 Topics: Adverse Drug Reaction Reporting Systems; Drug-Related Side Effects and Adverse Reactions; Flumazenil; Glucose; Humans; Medication Errors; Naloxone; Retrospective Studies	2023
Use of tracking drugs for the search of intra-hospital adverse reactions: a pharmacovigilance study. Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria, 2022, 04-26, Volume: 46, Issue:3 Topics: Adverse Drug Reaction Reporting Systems; Cross-Sectional Studies; Diphenhydramine; Drug-Related Side Effects and Adverse Reactions; Flumazenil; Hospitals; Humans; Loperamide; Naloxone; Pharmacovigilance; Promethazine	2022