flumazenil has been researched along with lidocaine in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.17) | 18.7374 |
| 1990's | 7 (29.17) | 18.2507 |
| 2000's | 7 (29.17) | 29.6817 |
| 2010's | 9 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Bagal, SK; Brown, AD; Cox, PJ; Omoto, K; Owen, RM; Pryde, DC; Sidders, B; Skerratt, SE; Stevens, EB; Storer, RI; Swain, NA | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Arakawa, K; Benson, KT; Goto, H; Yokoyama, M | 1 |
| Mody, I; Otis, TS | 1 |
| Bruguerolle, B; Emperaire, N | 2 |
| Backus, KH; Pflimlin, P; Trube, G | 1 |
| Birch, BR; Chave, H; Gelister, JS; Miller, RA; Parker, CJ | 1 |
| Anson, KM; Birch, BR; Clifford, E; Miller, RA | 1 |
| Cappell, MS | 1 |
| Trailović, SM; Varagić, VM | 1 |
3 review(s) available for flumazenil and lidocaine
| Article | Year |
|---|---|
Ion channels as therapeutic targets: a drug discovery perspective.
Topics: Drug Discovery; Humans; Ion Channels; Models, Molecular; Phylogeny | 2013 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Sedation and analgesia for gastrointestinal endoscopy during pregnancy.
Topics: Analgesia; Analgesics, Opioid; Cholangiopancreatography, Endoscopic Retrograde; Conscious Sedation; Diazepam; Endoscopy, Gastrointestinal; Female; Fentanyl; Fetus; Flumazenil; Humans; Hypnotics and Sedatives; Ketamine; Lidocaine; Meperidine; Naloxone; Pregnancy; Propofol; Risk Assessment; Triage | 2006 |
1 trial(s) available for flumazenil and lidocaine
| Article | Year |
|---|---|
Day-case surgery: enhanced recovery with flumazenil.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Female; Flumazenil; Humans; Lidocaine; Male; Midazolam; Middle Aged; Postoperative Period; Randomized Controlled Trials as Topic; Urologic Diseases | 1990 |
20 other study(ies) available for flumazenil and lidocaine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Effects of flumazenil on intravenous lidocaine-induced convulsions and anticonvulsant property of diazepam in rats.
Topics: Animals; Anticonvulsants; Bicarbonates; Blood Pressure; Carbon Dioxide; Convulsants; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Heart Rate; Hydrogen-Ion Concentration; Infusions, Intravenous; Lidocaine; Male; Oxygen; Partial Pressure; Rats; Rats, Inbred Strains; Seizures | 1992 |
Modulation of decay kinetics and frequency of GABAA receptor-mediated spontaneous inhibitory postsynaptic currents in hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Anesthetics, Local; Animals; Calcium Channels; Evoked Potentials; Flumazenil; Hippocampus; Kinetics; Lidocaine; Mathematics; Meglumine; Membrane Potentials; Midazolam; Models, Neurological; Neurons; Pentobarbital; Probability; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA-A; Synapses; Tetrodotoxin | 1992 |
Local anesthetic-induced toxicity may be modified by low doses of flumazenil.
Topics: Anesthesia, Local; Animals; Drug Overdose; Etidocaine; Flumazenil; Lidocaine; Male; Mepivacaine; Mice; Motor Activity; Seizures | 1992 |
Action of diazepam on the voltage-dependent Na+ current. Comparison with the effects of phenytoin, carbamazepine, lidocaine and flumazenil.
Topics: Action Potentials; Animals; Carbamazepine; Cell Line; Cells, Cultured; Diazepam; Embryo, Mammalian; Flumazenil; Kinetics; Lidocaine; Mice; Neuroblastoma; Neurons; Phenytoin; Sodium Channels; Spinal Cord | 1991 |
Transurethral resection of prostate under sedation and local anesthesia (sedoanalgesia). Experience in 100 patients.
Topics: Aged; Anesthesia, Local; Conscious Sedation; Flumazenil; Humans; Lidocaine; Male; Midazolam; Prostatectomy; Prostatic Hyperplasia; Time Factors; Urethral Obstruction; Urinary Retention | 1991 |
Flumazenil and lignocaine-induced toxicity: is the inverse agonist type activity circadian-time dependent?
Topics: Animals; Circadian Rhythm; Drug Interactions; Flumazenil; Lidocaine; Male; Mice; Seizures | 1993 |
The effect of ivermectin on convulsions in rats produced by lidocaine and strychnine.
Topics: Anesthetics, Local; Animals; Anticonvulsants; Antiparasitic Agents; Convulsants; Dose-Response Relationship, Drug; Flumazenil; GABA Modulators; Ivermectin; Lethal Dose 50; Lidocaine; Male; Rats; Rats, Wistar; Receptors, Glycine; Seizures; Strychnine | 2007 |