flumazenil has been researched along with isoniazid in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (32.00) | 18.7374 |
| 1990's | 4 (16.00) | 18.2507 |
| 2000's | 4 (16.00) | 29.6817 |
| 2010's | 9 (36.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Bernasconi, R; Leonhardt, T; Martin, P; Portet, C; Schmutz, M; Steulet, AF | 1 |
| Hellevuo, K; Kiianmaa, K; Korpi, ER | 1 |
| Biggio, G; Corda, MG; Giorgi, O; Longoni, B | 1 |
| Harris, C; Lal, H | 1 |
| Biry, P; Pieri, L | 1 |
| Costa, E; Ferrari, M; Ferrero, P; Guidotti, A | 1 |
| Costa, E | 1 |
| Corda, MG; Costa, E; Guidotti, A | 1 |
| Koe, BK; Lebel, LA | 1 |
| Morel, E; Perrault, G; Sanger, DJ; Zivkovic, B | 1 |
| Auta, J; Costa, E; Guidotti, A; Kozikowski, A; Ma, D; Romeo, E | 1 |
| Biggio, G; Cuccheddu, T; Floris, S; Ghiani, CA; Giusti, P; Motzo, C; Serra, M | 1 |
| Fushiki, T; Hanai, K; Imaizumi, M; Inoue, K; Kuroda, K; Manabe, Y; Sako, N; Yamamoto, T | 1 |
1 review(s) available for flumazenil and isoniazid
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
24 other study(ies) available for flumazenil and isoniazid
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Effects of benzodiazepine receptor ligands with different intrinsic activities on seizures induced by inhibition of GAD.
Topics: Animals; Anti-Anxiety Agents; Carbolines; Diazepam; Flumazenil; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippocampus; Isoniazid; Male; Mice; Mice, Inbred Strains; Pyrazoles; Reaction Time; Receptors, GABA-A; Seizures | 1992 |
Effect of GABAergic drugs on motor impairment from ethanol, barbital and lorazepam in rat lines selected for differential sensitivity to ethanol.
Topics: Animals; Barbital; Barbiturates; Dose-Response Relationship, Drug; Ethanol; Female; Flumazenil; GABA Antagonists; gamma-Aminobutyric Acid; Isoniazid; Lorazepam; Picrotoxin; Psychomotor Performance; Rats | 1989 |
Ro 15-4513, a partial inverse agonist for benzodiazepine recognition sites, has proconflict and proconvulsant effects in the rat.
Topics: Animals; Azides; Benzodiazepines; Carbolines; Conflict, Psychological; Convulsants; Flumazenil; Isoniazid; Male; Pentobarbital; Punishment; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1989 |
Interoceptive stimuli produced by an anxiogenic drug are mimicked by benzodiazepine antagonists in rats pretreated with isoniazid.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepinones; Brain Chemistry; Convulsants; Discrimination, Psychological; Flumazenil; gamma-Aminobutyric Acid; Humans; Isoniazid; Male; Pentobarbital; Pentylenetetrazole; Pyrazoles; Rats | 1985 |
Isoniazid-induced convulsions in rats: effects of Ro 15-1788 and beta-CCE.
Topics: Animals; Benzodiazepinones; Carbolines; Dose-Response Relationship, Drug; Drug Interactions; Flumazenil; Indoles; Isoniazid; Male; Rats; Rats, Inbred Strains; Seizures | 1985 |
Multiple signals in GABAergic transmission: pharmacological consequences.
Topics: Amino Acid Sequence; Animals; Benzodiazepinones; Brain Chemistry; Diazepam Binding Inhibitor; Electric Stimulation; Flumazenil; gamma-Aminobutyric Acid; Isoniazid; Nerve Tissue Proteins; Rats; Synaptic Membranes; Synaptic Transmission | 1984 |
Are benzodiazepine recognition sites functional entities for the action of endogenous effector(s) or merely drug receptor(s)?
Topics: Animals; Benzodiazepinones; Brain; Flumazenil; gamma-Aminobutyric Acid; Humans; Isoniazid; Neurotransmitter Agents; Receptors, Cell Surface; Receptors, GABA-A; Seizures; Synaptic Membranes; Synaptic Transmission | 1983 |
Specific proconvulsant action of an imidazobenzodiazepine (RO 15-1788) on isoniazid convulsions.
Topics: Animals; Benzodiazepinones; Brain; Convulsants; Drug Synergism; Flumazenil; gamma-Aminobutyric Acid; Isoniazid; Male; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter; Seizures | 1982 |
Contrasting effects of ethyl beta-carboline-3-carboxylate (beta CCE) and diazepam on cerebellar cyclic GMP content and antagonism of both effects by Ro 15-1788, a specific benzodiazepine receptor blocker.
Topics: Animals; Benzodiazepinones; Carbolines; Cerebellum; Cyclic GMP; Diazepam; Flumazenil; In Vitro Techniques; Indoles; Isoniazid; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Repeated treatment with alpidem, a new anxiolytic, does not induce tolerance or physical dependence.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Bicuculline; Carbolines; Convulsants; Diazepam; Drug Tolerance; Flumazenil; Imidazoles; Isoniazid; Male; Mice; Pentylenetetrazole; Pyridines; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders | 1993 |
Participation of mitochondrial diazepam binding inhibitor receptors in the anticonflict, antineophobic and anticonvulsant action of 2-aryl-3-indoleacetamide and imidazopyridine derivatives.
Topics: Aggression; Allosteric Regulation; Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Clonazepam; Desoxycorticosterone; Flumazenil; Imidazoles; Indoleacetic Acids; Isoniazid; Isoquinolines; Mitochondria; Phobic Disorders; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, GABA-A; Seizures; Zolpidem | 1993 |
Imidazenil, a new partial agonist of benzodiazepine receptors, reverses the inhibitory action of isoniazid and stress on gamma-aminobutyric acidA receptor function.
Topics: Animals; Benzodiazepines; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Convulsants; Flumazenil; GABA-A Receptor Antagonists; Imidazoles; Isoniazid; Male; Mice; Mice, Inbred Strains; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures; Stress, Physiological; Sulfur Radioisotopes; Tritium | 1994 |
Diazepam-binding inhibitor-like activity in rat cerebrospinal fluid after stimulation by an aversive quinine taste.
Topics: Animals; Cerebrospinal Fluid; Diazepam; Drinking; Flumazenil; GABA-A Receptor Antagonists; Glutathione; Hydra; Male; Mice; Peptide Fragments; Pronase; Quinine; Rats; Rats, Wistar; Sucrose; Taste | 2000 |