flumazenil and haloperidol

flumazenil has been researched along with haloperidol in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19907 (21.88)18.7374
1990's3 (9.38)18.2507
2000's10 (31.25)29.6817
2010's12 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Topliss, JG; Yoshida, F1
Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Engel, JA; Hulthe, P; Johannessen, K; Söderpalm, B; Svensson, L1
Allikmets, L; Lang, A; Soosaar, A; Vasar, E1
O'Brien, DP; White, FJ1
Karobath, M; Supavilai, P1
Allikmets, LKh; Maĭmets, MO; Nurk, AM; Soosaar, AKh; Vasar, EE1
Cagiano, R; Cuomo, V; De Salvia, MA; Maselli, MA; Racagni, G; Renna, G1
Overstreet, D; Pilotto, R; Singer, G1
Allikmets, LKh; Maĭmets, MO; Nurk, AM; Riago, LK; Vasar, EE1
Arnsten, AF; Goldman-Rakic, PS; Murphy, BL; Roth, RH1
Breese, GR; Knapp, DJ; Overstreet, DH1
Dean, B; McLeod, MC; Sundram, S1
Eyanagi, R; Imoto, M; Kuroki, H; Nishimura, S; Shimeno, H; Soeda, S; Toda, A; Uchiyama, H; Watanabe, S1
Reti, IM; Wachtel, LE; Ying, H1
Bispo-da-Silva, LB; da Silveira, NS; de Oliveira-Silva, GL; Lamanes, Bde F; Prado, LC1
Bailey, AM; Baum, RA; Horn, K; Justice, SN; Lewis, T; Morizio, K; Schultz, A; Weant, K1

Reviews

2 review(s) available for flumazenil and haloperidol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Review of Intranasally Administered Medications for Use in the Emergency Department.
    The Journal of emergency medicine, 2017, Volume: 53, Issue:1

    Topics: Administration, Intranasal; Anesthetics, Dissociative; Anticonvulsants; Antidotes; Antipsychotic Agents; Dexmedetomidine; Emergency Service, Hospital; Fentanyl; Flumazenil; Haloperidol; Humans; Hydromorphone; Hypnotics and Sedatives; Ketamine; Lorazepam; Midazolam; Naloxone; Narcotic Antagonists; Narcotics

2017

Other Studies

30 other study(ies) available for flumazenil and haloperidol

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Evidence for a role for dopamine in the diazepam locomotor stimulating effect.
    Psychopharmacology, 1991, Volume: 104, Issue:1

    Topics: alpha-Methyltyrosine; Animals; Benzazepines; Diazepam; Dopamine; Flumazenil; Haloperidol; Male; Methyltyrosines; Mice; Motor Activity; Spiperone; Stimulation, Chemical; Tyrosine 3-Monooxygenase

1991
Similar behavioral and biochemical effects of long-term haloperidol and caerulein treatment in albino mice.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 35, Issue:4

    Topics: Amphetamine; Animals; Brain; Ceruletide; Drug Interactions; Exploratory Behavior; Flumazenil; Haloperidol; Male; Mice; Muscimol; Time Factors

1990
Inhibition of non-dopamine cells in the ventral tegmental area by benzodiazepines: relationship to A10 dopamine cell activity.
    European journal of pharmacology, 1987, Oct-27, Volume: 142, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Diazepam; Flumazenil; Haloperidol; Iontophoresis; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Tegmentum Mesencephali

1987
Modulation of acetylcholine release from rat striatal slices by the GABA/benzodiazepine receptor complex.
    Life sciences, 1985, Feb-04, Volume: 36, Issue:5

    Topics: Acetylcholine; Animals; Atropine; Baclofen; Benzodiazepinones; Clonazepam; Corpus Striatum; Electric Stimulation; Flumazenil; gamma-Aminobutyric Acid; Haloperidol; In Vitro Techniques; Isoxazoles; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A

1985
[Nonuniform effect of prolonged haloperidol administration on the GABA(A) and benzodiazepine receptors in different parts of the brain].
    Biulleten' eksperimental'noi biologii i meditsiny, 1986, Volume: 101, Issue:4

    Topics: Animals; Behavior, Animal; Benzodiazepinones; Brain; Flumazenil; Haloperidol; Male; Mice; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Time Factors

1986
Ultrasonic vocalization in response to unavoidable aversive stimuli in rats: effects of benzodiazepines.
    Life sciences, 1988, Volume: 43, Issue:6

    Topics: Alprazolam; Animals; Benzodiazepines; Desipramine; Diazepam; Electroshock; Flumazenil; Haloperidol; Male; Rats; Rats, Inbred Strains; Ultrasonics; Vocalization, Animal

1988
Self-injection of diazepam in naive rats: effects of dose, schedule and blockade of different receptors.
    Psychopharmacology, 1984, Volume: 84, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Bicuculline; Diazepam; Dose-Response Relationship, Drug; Extinction, Psychological; Flumazenil; Haloperidol; Male; Naloxone; Rats; Receptors, Drug; Reinforcement Schedule; Self Administration

1984
[Effect of an imidazobenzodiazepine (RO 15-1788) on aggressive behavior in mice].
    Biulleten' eksperimental'noi biologii i meditsiny, 1984, Volume: 98, Issue:10

    Topics: Aggression; Animals; Apomorphine; Benzodiazepinones; Brain; Catalepsy; Dose-Response Relationship, Drug; Flumazenil; Haloperidol; Humans; Hydroxyindoleacetic Acid; Male; Mice; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Serotonin

1984
Increased dopamine turnover in the prefrontal cortex impairs spatial working memory performance in rats and monkeys.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Feb-06, Volume: 93, Issue:3

    Topics: Analysis of Variance; Animals; Benzazepines; Carbolines; Clozapine; Dopamine; Dopamine Antagonists; Female; Flumazenil; GABA Modulators; GABA-A Receptor Antagonists; Haloperidol; Macaca mulatta; Male; Maze Learning; Memory; Motor Activity; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Space Perception; Stress, Psychological

1996
Drug challenges reveal differences in mediation of stress facilitation of voluntary alcohol drinking and withdrawal-induced anxiety in alcohol-preferring P rats.
    Alcoholism, clinical and experimental research, 2007, Volume: 31, Issue:9

    Topics: Alcohol Drinking; Aminopyridines; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Benzodiazepines; Buspirone; Dopamine Antagonists; Ethanol; Flumazenil; GABA Modulators; Haloperidol; Indoles; Naloxone; Narcotic Antagonists; Olanzapine; Rats; Rats, Inbred Strains; Restraint, Physical; Serotonin Receptor Agonists; Stress, Physiological; Substance Withdrawal Syndrome

2007
Treatment with haloperidol and diazepam alters GABA(A) receptor density in the rat brain.
    Progress in neuro-psychopharmacology & biological psychiatry, 2008, Feb-15, Volume: 32, Issue:2

    Topics: Animals; Antipsychotic Agents; Autoradiography; Benzodiazepines; Binding Sites; Brain; Diazepam; Disease Models, Animal; Drug Combinations; Flumazenil; Haloperidol; Hippocampus; Humans; Injections, Intraperitoneal; Muscimol; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Schizophrenia; Thalamus; Tissue Distribution

2008
The stimulatory effects of caffeine with oseltamivir (Tamiflu) on light-dark behavior and open-field behavior in mice.
    Neuroscience letters, 2010, Jan-22, Volume: 469, Issue:2

    Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Antiviral Agents; Caffeine; Darkness; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Exploratory Behavior; Flumazenil; GABA Modulators; GABA-A Receptor Antagonists; Haloperidol; Male; Mice; Motor Activity; Neurotransmitter Agents; Oseltamivir; Pyrimidines; Random Allocation; Triazoles; Xanthines

2010
Stability of intraocular pressure after retinal reattachment surgery during electroconvulsive therapy for intractable self-injury in a 12-year-old autistic boy.
    The journal of ECT, 2014, Volume: 30, Issue:1

    Topics: Aggression; Anticonvulsants; Antipsychotic Agents; Autistic Disorder; Child; Electroconvulsive Therapy; Flumazenil; GABA Modulators; Haloperidol; Humans; Hypnotics and Sedatives; Intraocular Pressure; Lorazepam; Male; Ophthalmologic Surgical Procedures; Psychomotor Agitation; Retinal Detachment; Self-Injurious Behavior

2014
The aversive, anxiolytic-like, and verapamil-sensitive psychostimulant effects of pulegone.
    Biological & pharmaceutical bulletin, 2014, Volume: 37, Issue:5

    Topics: Animals; Anti-Anxiety Agents; Central Nervous System Stimulants; Choice Behavior; Conditioning, Psychological; Cyclohexane Monoterpenes; Diltiazem; Drug Interactions; Flumazenil; Grooming; Haloperidol; Hand Strength; Male; Maze Learning; Menthol; Mice; Monoterpenes; Motor Activity; Picrotoxin; Reinforcement, Psychology; Rotarod Performance Test; Verapamil

2014