flumazenil and gabapentin

flumazenil has been researched along with gabapentin in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.76)18.7374
1990's0 (0.00)18.2507
2000's8 (38.10)29.6817
2010's11 (52.38)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Choi, Y; Raymer, BK1
Porter, RJ1
Paz, L; Peter, Y; Pick, CG; Toren, P; Weizman, R1
Amsden, GW; Butler, TC; Rosen, RM; Wallace, AL1
Baron, M; Gromov, I; Hanselka, LL; Urschel, HC; White, L1
Anton, RF; Baros, AM; Latham, PK; Malcolm, R; Myrick, H; Randall, PK; Stewart, SH; Waid, R; Wright, TM1
Baron, M; Hanselka, LL; Urschel, HC1
Anton, RF; Baros, AM; Latham, PK; Myrick, H; Randall, PK; Schacht, JP; Waid, LR; Wright, TM1
Annon, J; Bholat, MA; Charuvastra, C; Chim, D; Doraimani, G; Dowling, PT; Heinzerling, K; Hillhouse, M; Ling, W; Shoptaw, S1
Anton, RF; Henderson, S; Li, X; Myrick, H; Randall, PK; Schacht, JP1
Foti, C; Masciullo, M; Molinari, M; Pichiorri, F; Scivoletto, G1

Reviews

2 review(s) available for flumazenil and gabapentin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Sleep modulating agents.
    Bioorganic & medicinal chemistry letters, 2019, 08-15, Volume: 29, Issue:16

    Topics: Animals; Humans; Sleep; Sleep Aids, Pharmaceutical; Sleep Wake Disorders; Wakefulness-Promoting Agents

2019

Trials

5 trial(s) available for flumazenil and gabapentin

ArticleYear
Efficacy of a combination of flumazenil and gabapentin in the treatment of alcohol dependence: relationship to alcohol withdrawal symptoms.
    Journal of clinical psychopharmacology, 2009, Volume: 29, Issue:4

    Topics: Administration, Oral; Adult; Alcohol Drinking; Alcoholism; Amines; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Female; Flumazenil; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Infusions, Intravenous; Logistic Models; Male; Medication Adherence; Middle Aged; Patient Selection; Sleep; Substance Withdrawal Syndrome; Temperance; Time Factors; Treatment Outcome

2009
A controlled trial of flumazenil and gabapentin for initial treatment of methylamphetamine dependence.
    Journal of psychopharmacology (Oxford, England), 2011, Volume: 25, Issue:2

    Topics: Adolescent; Adult; Amines; Amphetamine-Related Disorders; Anticonvulsants; Behavior, Addictive; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Female; Flumazenil; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Patient Compliance

2011
Neurocognitive performance, alcohol withdrawal, and effects of a combination of flumazenil and gabapentin in alcohol dependence.
    Alcoholism, clinical and experimental research, 2011, Volume: 35, Issue:11

    Topics: Adult; Alcohol Drinking; Alcoholism; Amines; Cognition; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Flumazenil; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; Middle Aged; Recurrence; Substance Withdrawal Syndrome; Treatment Outcome

2011
Double-blind placebo-controlled evaluation of the PROMETAâ„¢ protocol for methamphetamine dependence.
    Addiction (Abingdon, England), 2012, Volume: 107, Issue:2

    Topics: Adult; Amines; Amphetamine-Related Disorders; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Combinations; Female; Flumazenil; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Histamine Agonists; Humans; Hydroxyzine; Infusions, Intravenous; Male; Medication Adherence; Methamphetamine; Self Report

2012
Effects of a GABA-ergic medication combination and initial alcohol withdrawal severity on cue-elicited brain activation among treatment-seeking alcoholics.
    Psychopharmacology, 2013, Volume: 227, Issue:4

    Topics: Adult; Alcohol Drinking; Alcoholism; Amines; Brain; Cues; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Female; Flumazenil; Follow-Up Studies; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Secondary Prevention; Severity of Illness Index; Substance Withdrawal Syndrome; Treatment Outcome

2013

Other Studies

14 other study(ies) available for flumazenil and gabapentin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Mechanisms of action of new antiepileptic drugs.
    Epilepsia, 1989, Volume: 30 Suppl 1

    Topics: Acetamides; Acetates; Amines; Aminocaproates; Aminopyridines; Anti-Anxiety Agents; Anticonvulsants; Aspartic Acid; Benzodiazepines; Benzodiazepinones; Clobazam; Cyclohexanecarboxylic Acids; Dibenzocycloheptenes; Dizocilpine Maleate; Epilepsy; Felbamate; Flumazenil; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Imidazoles; Lamotrigine; Phenylcarbamates; Propylene Glycols; Receptors, GABA-A; Triazines; Vigabatrin

1989
Behavioral effects of agents active at the gamma-aminobutyric acid receptor complex in the staircase paradigm.
    Brain research, 2001, May-18, Volume: 901, Issue:1-2

    Topics: Acetates; Adjuvants, Immunologic; Amines; Animals; Anti-Anxiety Agents; Anxiety; Azabicyclo Compounds; Behavior, Animal; Brain; Clonazepam; Cyclohexanecarboxylic Acids; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Exploratory Behavior; Flumazenil; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Mice; Mice, Inbred ICR; Motor Activity; Neurons; Piperazines; Receptors, GABA-A

2001
Flumazenil and dialysis for gabapentin-induced coma.
    The Annals of pharmacotherapy, 2003, Volume: 37, Issue:1

    Topics: Acetates; Aged; Aged, 80 and over; Amines; Analgesics; Antidotes; Coma; Cyclohexanecarboxylic Acids; Flumazenil; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Phantom Limb; Renal Dialysis

2003
Open-label study of a proprietary treatment program targeting type A gamma-aminobutyric acid receptor dysregulation in methamphetamine dependence.
    Mayo Clinic proceedings, 2007, Volume: 82, Issue:10

    Topics: Adolescent; Adult; Aged; Amines; Cyclohexanecarboxylic Acids; Female; Flumazenil; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydroxyzine; Male; Methamphetamine; Middle Aged; Patient Dropouts; Prospective Studies; Receptors, GABA; Substance-Related Disorders

2007
Flumazenil therapy for a gabapentin-induced coma: a case report.
    Journal of medical case reports, 2021, May-09, Volume: 15, Issue:1

    Topics: Aged; Antidotes; Coma; Flumazenil; Gabapentin; Humans; Male; Quality of Life

2021