flumazenil and etomidate

flumazenil has been researched along with etomidate in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.25)18.7374
1990's1 (6.25)18.2507
2000's5 (31.25)29.6817
2010's8 (50.00)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Sun, H1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cheng, CR; Chuang, JY; Lai, KB; Lee, Y; Mok, MS; Sit, KF; Steen, SN; Wei, TT; Wong, KL; Wu, KH1
Ashton, D1
Fisch, HU; Kosel, M; Luginbühl, M; Rudolph, U; Schlaepfer, TE; Schmitt, W; Wielepp, P1
Bragulat, E; Coll-Vinent, B; Espinosa, G; Fernández, C; Millá, J; Miró, O; Sala, X; Sánchez, M1
Bailine, SH; Russ, MJ1
Cao, CH; Li, YW; Liu, XD; Ma, L; Sui, B1
Absalom, NL; Chebib, M; Chua, HC; Hanrahan, JR; Viswas, R1
Absalom, NL; Chebib, M; Christensen, ET; Chua, HC; Hartiadi, LY; Hoestgaard-Jensen, K; Jensen, AA; Ramzan, I1
Gharpure, A; Hibbs, RE; Howard, RJ; Kim, JJ; Lindahl, E; Noviello, CM; Teng, J; Walsh, RM; Zhu, S; Zhuang, Y1

Reviews

1 review(s) available for flumazenil and etomidate

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for flumazenil and etomidate

ArticleYear
[Does flumazenil antagonize the anesthetic effect of ketamine, etomidate or thiopental?].
    Ma zui xue za zhi = Anaesthesiologica Sinica, 1990, Volume: 28, Issue:4

    Topics: Adult; Etomidate; Female; Flumazenil; Humans; Ketamine; Male; Thiopental

1990
Sedation for cardioversion in the emergency department: analysis of effectiveness in four protocols.
    Annals of emergency medicine, 2003, Volume: 42, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia Recovery Period; Clinical Protocols; Conscious Sedation; Drug Therapy, Combination; Electric Countershock; Emergency Medical Services; Etomidate; Female; Flumazenil; GABA Modulators; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Myoclonus; Outcome and Process Assessment, Health Care; Propofol; Prospective Studies; Treatment Outcome

2003
Etomidate with or without flumazenil anesthesia for stem cell transplantation in autistic children.
    Drug metabolism and drug interactions, 2014, Volume: 29, Issue:1

    Topics: Anesthetics, Intravenous; Antidotes; Autistic Disorder; Blood Pressure; Child; Child, Preschool; Deep Sedation; Double-Blind Method; Etomidate; Female; Flumazenil; Heart Rate; Humans; Male; Pain, Postoperative; Postoperative Care; Spinal Puncture; Stem Cell Transplantation

2014

Other Studies

12 other study(ies) available for flumazenil and etomidate

ArticleYear
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Capture hydrolysis signals in the microsomal stability assay: molecular mechanisms of the alkyl ester drug and prodrug metabolism.
    Bioorganic & medicinal chemistry letters, 2012, Jan-15, Volume: 22, Issue:2

    Topics: Carboxylic Acids; Cytochrome P-450 Enzyme System; Esters; Humans; Hydrolysis; Microsomes; Models, Molecular; Molecular Structure; Prodrugs; Quantum Theory; Signal Transduction

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Diazepam, pentobarbital and D-etomidate produced increases in bicuculline seizure threshold; selective antagonism by RO15-1788, picrotoxin and (+/-)-DMBB.
    European journal of pharmacology, 1983, Oct-28, Volume: 94, Issue:3-4

    Topics: Animals; Barbiturates; Benzodiazepinones; Bicuculline; Diazepam; Etomidate; Flumazenil; Imidazoles; Male; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Seizures

1983
Diminished GABA(A) receptor-binding capacity and a DNA base substitution in a patient with treatment-resistant depression and anxiety.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2004, Volume: 29, Issue:2

    Topics: Adult; Anxiety Disorders; Binding Sites; Brain Mapping; Cerebral Cortex; Depression; Electroconvulsive Therapy; Etomidate; Exons; Flumazenil; Gene Silencing; Humans; Hypnotics and Sedatives; Iodine Isotopes; Male; Point Mutation; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon

2004
Asystole and bradycardia related to anesthetic induction during ECT: a case report.
    The journal of ECT, 2004, Volume: 20, Issue:3

    Topics: Adult; Anesthesia, General; Antidepressive Agents; Bradycardia; Depressive Disorder; Electroconvulsive Therapy; Etomidate; Female; Flumazenil; Glycopyrrolate; Heart Arrest; Humans; Succinylcholine

2004
The Direct Actions of GABA, 2'-Methoxy-6-Methylflavone and General Anaesthetics at β3γ2L GABAA Receptors: Evidence for Receptors with Different Subunit Stoichiometries.
    PloS one, 2015, Volume: 10, Issue:10

    Topics: Anesthetics, Intravenous; Animals; Cells, Cultured; Chlorides; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Etomidate; Female; Flavones; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; Humans; Propofol; Protein Subunits; Receptors, GABA-A; Xenopus laevis; Zinc Compounds

2015
Kavain, the Major Constituent of the Anxiolytic Kava Extract, Potentiates GABAA Receptors: Functional Characteristics and Molecular Mechanism.
    PloS one, 2016, Volume: 11, Issue:6

    Topics: Anesthetics; Animals; Anti-Anxiety Agents; Benzodiazepines; Diazepam; Drug Interactions; Drug Synergism; Etomidate; Flumazenil; Humans; Kava; Mutation; Propofol; Protein Subunits; Pyrones; Receptors, GABA-A; Xenopus laevis

2016
Shared structural mechanisms of general anaesthetics and benzodiazepines.
    Nature, 2020, Volume: 585, Issue:7824

    Topics: Allosteric Regulation; Anesthetics, General; Barbiturates; Benzodiazepines; Bicuculline; Binding Sites; Binding, Competitive; Cryoelectron Microscopy; Diazepam; Electrophysiology; Etomidate; Flumazenil; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Ligands; Models, Molecular; Molecular Conformation; Molecular Dynamics Simulation; Phenobarbital; Picrotoxin; Propofol; Receptors, GABA-A

2020