flumazenil has been researched along with clonidine in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (26.09) | 18.7374 |
| 1990's | 6 (26.09) | 18.2507 |
| 2000's | 8 (34.78) | 29.6817 |
| 2010's | 3 (13.04) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Coop, CF; McNaughton, N; Scott, DJ | 1 |
| Elsworth, JD; Ida, Y; Roth, RH | 1 |
| Baldwin, HA; File, SE | 1 |
| De Souza, RJ; Goodwin, GM; Green, AR | 1 |
| Chopin, P; File, SE; Pellow, S | 2 |
| Spealman, RD; Wettstein, JG | 1 |
| Emmett-Oglesby, MW; Lal, H; Lewis, MW; Spencer, DG | 1 |
| Chapouthier, G; Jacquot, F; Sara, S; Save, E; Venault, P | 1 |
| Matsumoto, K; Nguyen, TT; Watanabe, H; Yamasaki, K | 1 |
| Fujimoto, JM; Holmes, BB; Rady, JJ | 1 |
| Castro, JL; Ramirez, A; Ricci, D; Taira, CA | 1 |
| Choi, YM; Huh, IH; Jeong, JH; Lee, BC; Lee, SY; Min, YS; Sohn, UD | 1 |
| Ozaki, S | 1 |
2 review(s) available for flumazenil and clonidine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Drug dependence syndrome as a side effect of medical drug use].
Topics: Central Nervous System Agents; Clonidine; Flumazenil; Humans; Naloxone; Psychotherapy, Group; Self-Help Groups; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors | 2007 |
21 other study(ies) available for flumazenil and clonidine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Pindolol antagonizes the effects on hippocampal rhythmical slow activity of clonidine, baclofen and 8-OH-DPAT, but not chlordiazepoxide and sodium amylobarbitone.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Amobarbital; Animals; Baclofen; Chlordiazepoxide; Clonidine; Electric Stimulation; Electrodes; Electroencephalography; Flumazenil; Hippocampus; Male; Pindolol; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes | 1992 |
Anxiogenic beta-carboline FG 7142 produces activation of noradrenergic neurons in specific brain regions of rats.
Topics: Animals; Brain Chemistry; Carbolines; Clonidine; Flumazenil; Male; Methoxyhydroxyphenylglycol; Neurons; Norepinephrine; Rats; Rats, Inbred Strains; Sympathetic Nervous System | 1991 |
Caffeine-induced anxiogenesis: the role of adenosine, benzodiazepine and noradrenergic receptors.
Topics: 2-Chloroadenosine; Adenosine; Alprazolam; Anxiety; Caffeine; Chlordiazepoxide; Clonidine; Flumazenil; Motor Activity; Muscle Relaxants, Central; Norepinephrine; Propranolol; Receptors, Adrenergic; Receptors, GABA-A; Receptors, Purinergic; Social Behavior | 1989 |
The pharmacology of the hypothermic response in mice to 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT). A model of presynaptic 5-HT1 function.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Apomorphine; Benzodiazepinones; Body Temperature; Clonidine; Fenclonine; Flumazenil; Injections, Intraventricular; Male; Mice; Mice, Inbred C57BL; Naphthalenes; Tetrahydronaphthalenes; Time Factors | 1985 |
The effects of yohimbine on exploratory and locomotor behaviour are attributable to its effects at noradrenaline and not at benzodiazepine receptors.
Topics: Adrenergic alpha-Antagonists; Animals; Benzodiazepinones; Chlordiazepoxide; Clonidine; Drug Interactions; Exploratory Behavior; Flumazenil; Male; Motor Activity; Rats; Receptors, GABA-A; Yohimbine | 1986 |
Are the anxiogenic effects of yohimbine mediated by its action at benzodiazepine receptors?
Topics: Animals; Arousal; Benzodiazepinones; Brain; Chlordiazepoxide; Clonidine; Dose-Response Relationship, Drug; Flumazenil; Male; Rats; Receptors, Adrenergic, alpha; Receptors, GABA-A; Social Behavior; Social Environment; Yohimbine | 1985 |
Distinctive behavioral effects of the pyrazoloquinoline CGS 8216 in squirrel monkeys.
Topics: Animals; Behavior, Animal; Benzodiazepines; Clonidine; Diazepam; Flumazenil; Male; Pyrazoles; Saimiri | 1988 |
Bioassay of subjective effects associated with benzodiazepine withdrawal in animals: a novel direction in dependence research.
Topics: Animals; Benzodiazepinones; Biological Assay; Clonidine; Conditioning, Operant; Diazepam; Discrimination Learning; Flumazenil; Generalization, Stimulus; Humans; Male; Pentobarbital; Pentylenetetrazole; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders | 1984 |
Anxiogenic-like effects of yohimbine and idazoxan in two behavioral situations in mice.
Topics: Adrenergic alpha-Antagonists; Animals; Anxiety; Behavior, Animal; Choice Behavior; Clonidine; Conditioning, Classical; Conflict, Psychological; Dioxanes; Flumazenil; Idazoxan; Male; Mice; Yohimbine | 1993 |
Involvement of supraspinal GABA receptors in majonoside-R2 suppression of clonidine-induced antinociception in mice.
Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Clonidine; Flumazenil; GABA Antagonists; GABA Modulators; Ginsenosides; Idazoxan; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Spinal; Male; Mice; Pain Measurement; Picrotoxin; Receptors, GABA-A; Saponins; Spinal Cord | 1997 |
Supraspinal flumazenil inhibits the antianalgesic action of spinal dynorphin A (1-17).
Topics: Analgesia; Analgesics; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Dynorphins; Flumazenil; GABA Agonists; GABA-A Receptor Agonists; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Naltrexone; Physostigmine | 1998 |
Central benzodiazepine involvement in clonidine cardiovascular actions.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Atropine Derivatives; Blood Pressure; Carbolines; Cardiovascular Agents; Clonidine; Diazepam; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; Heart Rate; Infusions, Intravenous; Injections, Intraventricular; Male; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, GABA-A; Stereotaxic Techniques; Time Factors; Yohimbine | 1999 |
The influences of extremely low frequency magnetic fields on clonidine-induced sleep in 2-day-old chicks.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Animals, Newborn; Bicuculline; Brain Chemistry; Chickens; Chromatography, High Pressure Liquid; Clonidine; Dose-Response Relationship, Drug; Electrochemistry; Electromagnetic Fields; Flumazenil; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Norepinephrine; Sleep; Tyrosine | 2001 |