Compounds > flumazenil

flumazenil and clobazam

flumazenil has been researched along with clobazam in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's5 (50.00)18.2507
2000's2 (20.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Tietz, EI1
Löscher, W; Rundfeldt, C1
Porter, RJ1
Schmidt, D1
Brodie, MJ; Duncan, S; Gillen, GJ1
Nakamura, F; Nishimura, S; Seino, M; Suzuki, S; Yagi, K1
Li, M; Rosenberg, HC; Szabo, A1

Reviews

1 review(s) available for flumazenil and clobazam

ArticleYear
Clobazam for treatment of intractable epilepsy: a critical assessment.
    Epilepsia, 1994, Volume: 35 Suppl 5

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Clinical Trials as Topic; Clobazam; Double-Blind Method; Drug Administration Schedule; Drug Tolerance; Epilepsy; Flumazenil; Humans; Meta-Analysis as Topic; Placebos

1994

Trials

1 trial(s) available for flumazenil and clobazam

ArticleYear
Lack of effect of concomitant clobazam on interictal 123I-iomazenil SPECT.
    Epilepsy research, 1993, Volume: 15, Issue:1

    Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Brain; Clobazam; Epilepsy; Female; Flumazenil; Humans; Iodine Radioisotopes; Male; Tomography, Emission-Computed, Single-Photon

1993

Other Studies

8 other study(ies) available for flumazenil and clobazam

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Repeated anticonvulsant testing: contingent tolerance to diazepam and clobazam in kindled rats.
    Epilepsy research, 1992, Volume: 11, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Clobazam; Diazepam; Drug Tolerance; Flumazenil; Kindling, Neurologic; Male; Radioligand Assay; Rats; Rats, Inbred Strains; Seizures

1992
Development of tolerance to clobazam in fully kindled rats: effects of intermittent flumazenil administration.
    European journal of pharmacology, 1990, May-16, Volume: 180, Issue:2-3

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Benzodiazepines; Benzodiazepinones; Clobazam; Drug Tolerance; Electric Stimulation; Electrodes, Implanted; Female; Flumazenil; Half-Life; Hypnotics and Sedatives; Injections, Intraperitoneal; Kindling, Neurologic; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome

1990
Mechanisms of action of new antiepileptic drugs.
    Epilepsia, 1989, Volume: 30 Suppl 1

    Topics: Acetamides; Acetates; Amines; Aminocaproates; Aminopyridines; Anti-Anxiety Agents; Anticonvulsants; Aspartic Acid; Benzodiazepines; Benzodiazepinones; Clobazam; Cyclohexanecarboxylic Acids; Dibenzocycloheptenes; Dizocilpine Maleate; Epilepsy; Felbamate; Flumazenil; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Imidazoles; Lamotrigine; Phenylcarbamates; Propylene Glycols; Receptors, GABA-A; Triazines; Vigabatrin

1989
Effects of clobazam and its active metabolite on GABA-activated currents in rat cerebral neurons in culture.
    Epilepsia, 1996, Volume: 37, Issue:8

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Cells, Cultured; Cerebral Cortex; Chloride Channels; Clobazam; Dose-Response Relationship, Drug; Epilepsy; Flumazenil; gamma-Aminobutyric Acid; Humans; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, GABA; Synaptic Transmission

1996
Evaluation of native GABA(A) receptors containing an alpha 5 subunit.
    European journal of pharmacology, 2001, Feb-09, Volume: 413, Issue:1

    Topics: Alkynes; Animals; Anti-Anxiety Agents; Anticonvulsants; Autoradiography; Benzodiazepines; Cerebellum; Clobazam; Clonazepam; Diazepam; Flumazenil; Flunitrazepam; GABA-A Receptor Agonists; Hippocampus; Imidazoles; Male; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, GABA-A

2001