flumazenil and carbamazepine

flumazenil has been researched along with carbamazepine in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19904 (16.67)18.7374
1990's3 (12.50)18.2507
2000's6 (25.00)29.6817
2010's11 (45.83)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Topliss, JG; Yoshida, F1
Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Ahman, M; Holmén, AG; Wan, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Backus, KH; Pflimlin, P; Trube, G1
Benkert, O; Heuser, I; Wetzel, H1
Elsasser, S; Ritz, R; Scollo-Lavizzari, G; Zuber, M1
Chen Chow, S; Johnston, GA; Skerritt, JH1
Kögler, A; Staedt, J; Steinhoff, BJ; Stoppe, G1
Chodorowski, Z; Sein Anand, J1
Hirashima, Y; Morimoto, M; Nishimura, A; Osamura, T; Sugimoto, T1
Hoffmann, K; Janhsen, K; Roser, P1
Baandrup, L; Ebdrup, BH; Glenthøj, BY; Gluud, C; Lindschou, J; Rasmussen, JØ1

Reviews

3 review(s) available for flumazenil and carbamazepine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The problems of long-term treatment with benzodiazepines and related substances.
    Deutsches Arzteblatt international, 2015, Jan-05, Volume: 112, Issue:1-2

    Topics: Benzodiazepines; Carbamazepine; Flumazenil; Germany; Humans; Prevalence; Risk Factors; Substance Withdrawal Syndrome; Substance-Related Disorders; Valproic Acid

2015
Pharmacological interventions for benzodiazepine discontinuation in chronic benzodiazepine users.
    The Cochrane database of systematic reviews, 2018, Mar-15, Volume: 3

    Topics: Adult; Antidepressive Agents; Aspartic Acid; Benzodiazepines; Buspirone; Carbamazepine; Ethylamines; Flumazenil; Homeopathy; Humans; Imidazoles; Lithium Compounds; Melatonin; Paroxetine; Pregabalin; Progesterone; Pyridines; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome; Sulfides; Withholding Treatment

2018

Other Studies

21 other study(ies) available for flumazenil and carbamazepine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations

2002
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Action of diazepam on the voltage-dependent Na+ current. Comparison with the effects of phenytoin, carbamazepine, lidocaine and flumazenil.
    Brain research, 1991, May-10, Volume: 548, Issue:1-2

    Topics: Action Potentials; Animals; Carbamazepine; Cell Line; Cells, Cultured; Diazepam; Embryo, Mammalian; Flumazenil; Kinetics; Lidocaine; Mice; Neuroblastoma; Neurons; Phenytoin; Sodium Channels; Spinal Cord

1991
Stupor and affective state: alleviation of psychomotor disturbances by lorazepam and recurrence of symptoms after Ro 15-1788.
    The Journal of nervous and mental disease, 1987, Volume: 175, Issue:4

    Topics: Adult; Carbamazepine; Coma; Depressive Disorder; Drug Interactions; Drug Therapy, Combination; Female; Flumazenil; Humans; Lorazepam; Mutism

1987
Flumazenil (Anexate) in severe intoxication with carbamazepine (Tegretol).
    European neurology, 1988, Volume: 28, Issue:3

    Topics: Adult; Carbamazepine; Drug Interactions; Electroencephalography; Female; Flumazenil; Humans; Injections, Intravenous

1988
Interactions of carbamazepine with benzodiazepine receptors.
    The Journal of pharmacy and pharmacology, 1983, Volume: 35, Issue:7

    Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Binding, Competitive; Brain; Carbamazepine; Flumazenil; In Vitro Techniques; Kinetics; Male; Mice; Rats; Receptors, Cell Surface; Receptors, GABA-A; Synaptosomes

1983
Changes of central benzodiazepine receptor density in the course of anticonvulsant treatment in temporal lobe epilepsy.
    Seizure, 1995, Volume: 4, Issue:1

    Topics: Adult; Brain Mapping; Carbamazepine; Epilepsy, Temporal Lobe; Female; Flumazenil; Humans; Image Processing, Computer-Assisted; Radioligand Assay; Receptors, GABA-A; Temporal Lobe; Tomography, Emission-Computed, Single-Photon

1995
[Suicidal poisoning with benzodiazepines].
    Przeglad lekarski, 1997, Volume: 54, Issue:6

    Topics: Adolescent; Adult; Aged; Alcoholism; Benzodiazepines; Carbamazepine; Coma; Ethanol; Female; Flumazenil; Humans; Male; Mental Disorders; Middle Aged; Poland; Substance-Related Disorders; Suicide, Attempted

1997
Alternative psychosis and dysgraphia accompanied by forced normalization in a girl with occipital lobe epilepsy.
    Epilepsy & behavior : E&B, 2008, Volume: 12, Issue:3

    Topics: Agraphia; Anticonvulsants; Carbamazepine; Child; Electroencephalography; Epilepsies, Partial; Female; Flumazenil; Humans; Psychotic Disorders; Tomography, Emission-Computed, Single-Photon

2008