flumazenil and butorphanol

flumazenil has been researched along with butorphanol in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (16.67)18.2507
2000's6 (50.00)29.6817
2010's3 (25.00)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Benson, GJ; Gross, ME; Olson, WA; Thurmon, JC; Tranquilli, WJ1
Benson, GJ; Lemke, KA; Olson, WA; Thurmon, JC; Tranquilli, WJ1
Horne, WA; Kelly, BT; Larsen, RS; Loomis, MR; Sladky, KK; Stoskopf, MK1
Spelman, LH1
Amari, M; Bonato, F; Brioschi, FA; Di Cesare, F; Giordano, A; Magnone, W; Moretti, P; Pecile, A; Rabbogliatti, V; Ravasio, G1

Reviews

1 review(s) available for flumazenil and butorphanol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for flumazenil and butorphanol

ArticleYear
Ability of flumazenil, butorphanol, and naloxone to reverse the anesthetic effects of oxymorphone-diazepam in dogs.
    Journal of the American Veterinary Medical Association, 1996, Aug-15, Volume: 209, Issue:4

    Topics: Adjuvants, Anesthesia; Anesthetics, Combined; Animals; Butorphanol; Cross-Over Studies; Diazepam; Dogs; Drug Combinations; Female; Flumazenil; Male; Naloxone; Narcotic Antagonists; Oxymorphone; Time Factors

1996

Other Studies

10 other study(ies) available for flumazenil and butorphanol

ArticleYear
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Yohimbine/flumazenil antagonism of hemodynamic alterations induced by a combination of midazolam, xylazine, and butorphanol in dogs.
    Journal of the American Veterinary Medical Association, 1992, Dec-15, Volume: 201, Issue:12

    Topics: Anesthesia; Anesthetics; Animals; Blood Pressure; Butorphanol; Cardiac Output; Dogs; Female; Flumazenil; Heart Rate; Hemodynamics; Male; Midazolam; Stroke Volume; Vascular Resistance; Xylazine; Yohimbine

1992
Cardiorespiratory effects of medetomidine-butorphanol, medetomidine-butorphanol-diazepam, and medetomidine-butorphanol-ketamine in captive red wolves (Canis rufus).
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2002, Volume: 33, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthetics, Dissociative; Animals; Animals, Zoo; Blood Pressure; Body Temperature; Butorphanol; Diazepam; Drug Combinations; Female; Flumazenil; GABA Modulators; Heart Rate; Hypertension; Hypnotics and Sedatives; Imidazoles; Immobilization; Ketamine; Male; Medetomidine; Muscle Relaxation; Naloxone; Narcotic Antagonists; Narcotics; Respiration; Wolves

2002
Reversible anesthesia of captive California sea lions (Zalophus californianus) with medetomidine, midazolam, butorphanol, and isoflurane.
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2004, Volume: 35, Issue:1

    Topics: Anesthetics, Combined; Anesthetics, Inhalation; Animals; Antidotes; Butorphanol; Dose-Response Relationship, Drug; Female; Flumazenil; Heart Rate; Hypnotics and Sedatives; Imidazoles; Immobilization; Isoflurane; Medetomidine; Midazolam; Naltrexone; Narcotic Antagonists; Narcotics; Respiration; Sea Lions; Time Factors

2004
Comparison of two injectable anaesthetic protocols in Egyptian fruit bats (Rousettus aegyptiacus) undergoing gonadectomy.
    Scientific reports, 2022, 09-24, Volume: 12, Issue:1

    Topics: Anesthetics; Animals; Butorphanol; Castration; Chiroptera; Chlorides; Dexmedetomidine; Flumazenil; Hypnotics and Sedatives; Isoflurane; Ketamine; Midazolam; Sodium

2022