flumazenil has been researched along with bicuculline in 117 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 47 (40.17) | 18.7374 |
| 1990's | 37 (31.62) | 18.2507 |
| 2000's | 19 (16.24) | 29.6817 |
| 2010's | 9 (7.69) | 24.3611 |
| 2020's | 5 (4.27) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Ohno, M; Watanabe, S; Yamamoto, T | 1 |
| Dubrovina, NI; Finkelberg, AL; Ilyutchenok, RY; Loskutova, LV | 1 |
| Ducić, I; Polc, P | 1 |
| Agmo, A; Fernández, H | 1 |
| Engel, JA; Söderpalm, B | 2 |
| Ichihara, K; Kameyama, T; Nabeshima, T; Tohyama, K | 2 |
| Airaksinen, MM; MacDonald, E; Rägo, L; Saano, V | 1 |
| Blakeman, DP; Im, WB | 1 |
| Leslie, JC; Shephard, RA; Toal, L | 1 |
| De Luca, C; De Medici, D; Massotti, M | 1 |
| Hicks, TP; Oka, JI | 1 |
| Elgoyhen, AB; Kazanietz, MG | 1 |
| Kameyama, T; Nabeshima, T; Tohyama, K | 1 |
| Edwards, M; Gent, JP; Goodchild, CS; Serrao, JM | 1 |
| Danielou, G; Lloyd, GK; Thuret, F | 1 |
| Costa, E; Mienville, JM; Vicini, S | 1 |
| Alpern, HP; McIntyre, TD | 1 |
| Hamilton, MS; Shephard, RA | 1 |
| Egbe, PC | 1 |
| Gallager, DW; Heninger, C; Hernandez, TD; Wilson, MA | 1 |
| Egbe, P; Engel, JA; Liljequist, S; Söderpalm, B | 1 |
| Kumasaka, Y; Ueki, S; Yamamoto, T | 1 |
| Bassett, ML; Jones, EA; Mullen, KD; Skolnick, P | 1 |
| Graeff, FG; Milani, H | 1 |
| Cox, DH; Guidotti, A; Santi, MR | 1 |
| McCabe, RT; Olsen, RW; Wamsley, JK; Yezuita, JP | 1 |
| De Medici, D; Gatta, F; Longo, VG; Massotti, M | 1 |
| Ennis, C; Minchin, MC | 1 |
| Greentree, SG; Pertwee, RG; Swift, PA | 1 |
| Molodavkin, GM; Ostrovskaia, RU | 1 |
| Akhundov, RA; Rozhanets, VV; Val'dman, AV; Voronina, TA | 1 |
| Danchev, N | 1 |
| Kuriyama, K; Taguchi, J | 1 |
| Hara, T; Kawazawa, S; Mizuki, Y; Ushijima, I; Yamada, M | 1 |
| Rastogi, SK; Ticku, MK | 1 |
| Bold, JM; Gardner, CR; Walker, RJ | 1 |
| Haefely, W; Möhler, H; Richards, JG; Schoch, P | 1 |
| Biggio, G; Corda, MG | 1 |
| Astier, H; Roussel, JP; Tapia-Arancibia, L | 1 |
| Kulkarni, SK; Kunchandy, J | 1 |
| Ferrario, P; Hafner, B; Mantegazza, P; Tammiso, R; Zambotti, F; Zonta, N | 1 |
| Alho, H; Costa, E; Mienville, JM; Santi, MR; Vaccarino, FM; Vicini, S | 1 |
| Kavaliers, M; Wiebe, JP | 2 |
| Gallager, DW; Gonsalves, SF | 1 |
| Idemudia, SO; Lal, H; Mathis, DA | 1 |
| Majewska, MD; Mienville, JM; Vicini, S | 1 |
| Little, HJ; Wardley-Smith, B | 1 |
| Bortolotto, ZA; Cavalheiro, EA; Ikonomidou, C; Mello, LE; Turski, L; Turski, WA | 1 |
| Little, HJ | 1 |
| Engel, JA; Liljequist, S | 2 |
| Overstreet, D; Pilotto, R; Singer, G | 1 |
| Janiszewski, W; Schwarz, M; Sontag, KH; Turski, L | 1 |
| Vellucci, SV; Webster, RA | 1 |
| Ashton, D | 1 |
| Ramanjaneyulu, R; Ticku, MK | 1 |
| Lee, EK; Ross, RJ; Walters, JR; Waszczak, BL | 1 |
| Clineschmidt, BV | 1 |
| Bichard, AR; Little, HJ | 1 |
| Kaneto, H; Rahman, AF; Takahashi, M | 1 |
| Colwell, DD; Kavaliers, M | 1 |
| Iwasaki, T; Nakagawa, Y | 1 |
| Niles, LP; Tenn, CC | 2 |
| Dubrovina, NI | 1 |
| Sanders, SK; Shekhar, A | 1 |
| Morel, E; Perrault, G; Sanger, DJ; Zivkovic, B | 1 |
| Ishima, T; Iwasaki, T; Kimura, K; Nakagawa, Y | 1 |
| Pericić, D; Pivac, N | 1 |
| Contarino, A; Giusti, P; Lipartiti, M; Mariot, R; Zanotti, A | 1 |
| Hansen, HC; Jackson, HC; Judge, ME; Klitgaard, H; Kristiansen, M; Suzdak, PD; Swedberg, MD | 1 |
| Feng, J; Kendig, JJ | 1 |
| Davies, PA; Hales, TG; Hanna, MC; Kirkness, EF | 1 |
| Bujas, M; Pericić, D | 1 |
| Kasaba, T; Takasaki, M; Takeshita, M | 1 |
| Fernández-Guasti, A; López-Rubalcava, C | 1 |
| Kuribara, H; Maruyama, Y; Stavinoha, WB | 1 |
| Del Río, J; Díez-Ariza, M; Lasheras, B; Ramírez, MJ | 1 |
| Contarino, A; Giusti, P; Lipartiti, M; Natolino, F; Zanotti, A | 1 |
| Baur, R; Buhr, A; Sigel, E | 1 |
| Crowe, SF; Farkas, L | 1 |
| Gillardin, J; Poisbeau, P; Rybalchenko, V; Schlichter, R; Verleye, M | 1 |
| Ansaldo, MA; Fedele, E; Raiteri, M; Varnier, G | 1 |
| Kaur, G; Kulkarni, SK; Raghavendra, V | 1 |
| Choi, YM; Huh, IH; Jeong, JH; Lee, BC; Lee, SY; Min, YS; Sohn, UD | 1 |
| Nemmani, KV; Ramarao, P | 1 |
| Hamann, M; Richter, A | 1 |
| Gatch, MB; Jung, ME; Lal, H; Wallis, CJ | 1 |
| Del Río, J; Diez-Ariza, M; García-Alloza, M; Lasheras, B; Ramírez, MJ | 1 |
| Masuzawa, M; Miyamoto, E; Murayama, T; Nagata, A; Nakao, S; Shingu, K | 1 |
| Molina-Hernández, M; Olivera Lopez, JI; Pérez García, J; Tellez-Alcántara, NP; Teresa Jaramillo, M | 1 |
| Hansen, SL; Sánchez, C; Sperling, BB | 1 |
| Choi, KB; Jeong, JH; Moon, NJ; Park, ES; Sohn, UD | 1 |
| Baur, R; Senn, M; Séquin, U; Sigel, E; Simmen, U | 1 |
| Carai, MA; Colombo, G; Gessa, GL | 1 |
| Hirano, S; Kamei, J; Miyata, S | 1 |
| Jang, CG; Lee, SY; Yu, HS | 1 |
| Cho, YW; Jang, CG; Jin, C; Jung, JW; Lee, JJ; Oh, TH; Ryu, JH; Yoon, BH | 1 |
| Furuyashiki, T; Miyamoto, C; Narumiya, S; Ohinata, K; Suzuki, C | 1 |
| Egashira, N; Fujiwara, M; Ishibashi, A; Iwasaki, K; Mishima, K; Nishimura, R; Nogami, A; Oishi, R; Takasaki, K; Uchida, N | 1 |
| Choi, HJ; Kim, DE; Kim, DH; Kim, NJ; Oh, HA | 1 |
| do Rego, JL; Vaudry, D; Vaudry, H | 1 |
| Allio, A; Calorio, C; Carbone, E; Franchino, C; Gavello, D; Marcantoni, A | 1 |
| Egashira, N; Iba, H; Iwasaki, K; Katsurabayashi, S; Kawanaka, R; Kubota, K; Kuwano, H; Moriyama, H; Nagao, M; Watanabe, T | 1 |
| Covolan, L; de Castro, AC; de Oliveira, JA; de Souza, AS; Del Bel, EA; Mograbi, KM; Sales, PJ | 1 |
| Josiane Ojong, L; Jules Fifen, J; Kameni Njapdounke, JS; Kavaye Kandeda, A; Ngo Bum, E; Nkamguie Nkantchoua, GC; Sotoing Taiwe, G | 1 |
| Hibbs, RE; Kim, JJ; Noviello, CM; Teng, J; Walsh, RM; Zhu, S | 1 |
| da Silva Oliveira, GL; da Silva, JCCL; de Castro Almeida, FR; Dos Santos C L da Silva, AP; Feitosa, CM | 1 |
| Gharpure, A; Hibbs, RE; Howard, RJ; Kim, JJ; Lindahl, E; Noviello, CM; Teng, J; Walsh, RM; Zhu, S; Zhuang, Y | 1 |
| Esumi, S; Izushi, Y; Kitamura, Y; Matsumoto, D; Noda, Y; Sendo, T; Ushio, S; Wada, Y | 1 |
| Chen, D; Guo, W; Hu, H; Jiang, W; Li, J; Li, Y; Liu, H; Mu, K; Ning, N; Yu, X; Zhang, C; Zheng, J; Zhou, Y | 1 |
| Chai, X; Chen, S; Gao, X; Huang, L; Jiao, S; Li, J; Ma, X; Tu, P; Wuken, S | 1 |
1 review(s) available for flumazenil and bicuculline
| Article | Year |
|---|---|
Benzodiazepine receptors resolved.
Topics: Animals; Antibodies, Monoclonal; Autoradiography; Benzodiazepines; Benzodiazepinones; Bicuculline; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Chlorides; Clonazepam; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Histocytochemistry; Humans; Immunologic Techniques; Ionophores; Muscimol; Neurons; Radioisotopes; Radioligand Assay; Receptors, GABA-A; Spinal Cord; Synapses; Tissue Distribution | 1986 |
116 other study(ies) available for flumazenil and bicuculline
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Intrahippocampal injections of benzodiazepine and muscimol impair working memory but not reference memory of rats in the three-panel runway task.
Topics: Animals; Bicuculline; Chlordiazepoxide; Flumazenil; Hippocampus; Male; Memory; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A | 1992 |
Neurochemical mechanisms of memory control.
Topics: Amnesia; Animals; Bicuculline; Brain; Cats; Dopamine; Evoked Potentials; Flumazenil; GABA-A Receptor Antagonists; Male; Memory; Mice; Mice, Inbred BALB C; Neurotransmitter Agents; Norepinephrine; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A | 1992 |
Benzodiazepine antagonist flumazenil reduces bicuculline-induced enhancement of neuronal activity in the spinal cord.
Topics: Animals; Bicuculline; Cats; Epilepsy; Evoked Potentials; Flumazenil; Male; Motor Neurons; Receptors, GABA-A; Spinal Cord | 1991 |
Benzodiazepine receptor ligands and sexual behavior in the male rat: the role of GABAergic mechanisms.
Topics: Animals; Bicuculline; Carbolines; Chlordiazepoxide; Diazepam; Flumazenil; gamma-Aminobutyric Acid; Male; Motor Activity; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sexual Behavior, Animal | 1991 |
Involvement of the GABAA/benzodiazepine chloride ionophore receptor complex in the 5,7-DHT Induced anticonflict effect.
Topics: 5,7-Dihydroxytryptamine; Animals; Anti-Anxiety Agents; Azides; Benzodiazepines; Bicuculline; Diazepam; Drinking Behavior; Electroshock; Flumazenil; Hippocampus; Injections, Intraventricular; Limbic System; Male; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin | 1991 |
Involvement of GABAergic systems in benzodiazepine-induced impairment of passive avoidance learning in mice.
Topics: Animals; Anti-Anxiety Agents; Avoidance Learning; Bicuculline; Chlordiazepoxide; Drug Interactions; Flumazenil; GABA Antagonists; gamma-Aminobutyric Acid; Male; Memory; Mice; Mice, Inbred Strains; Muscimol; Picrotoxin | 1991 |
The effect of medetomidine on GABA and benzodiazepine receptors in vivo: lack of anxiolytic but some evidence of possible stress-protective activity.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Bicuculline; Brain; Cerebral Cortex; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Imidazoles; Kidney; Male; Medetomidine; Muscimol; Myocardium; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Stimulation, Chemical; Stress, Physiological; Tritium | 1991 |
Correlation between gamma-aminobutyric acidA receptor ligand-induced changes in t-butylbicyclophosphoro[35S]thionate binding and 36Cl- uptake in rat cerebrocortical membranes.
Topics: Animals; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Cerebral Cortex; Chloride Channels; Chlorides; Desoxycorticosterone; Diazepam; Ethanol; Flumazenil; gamma-Aminobutyric Acid; In Vitro Techniques; Ligands; Membrane Proteins; Pentobarbital; Pregnanolone; Rats; Receptors, GABA-A; Synaptosomes | 1991 |
Effects of chlordiazepoxide and putative anxiogenics on conditioned suppression in rats.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Arousal; Avoidance Learning; Bicuculline; Chlordiazepoxide; Conditioning, Classical; Dose-Response Relationship, Drug; Electroshock; Fear; Flumazenil; Male; Picrotoxin; Rats; Rats, Inbred Strains | 1991 |
Relative efficacies of benzodiazepine receptor agonists in affecting red nucleus electrical activity in rabbits.
Topics: Animals; Bicuculline; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Flunitrazepam; Imidazoles; Isoquinolines; Male; Pentylenetetrazole; Pyridazines; Pyridines; Rabbits; Receptors, GABA-A; Red Nucleus; Zolpidem | 1990 |
Benzodiazepines and synaptic processing in the spatial domain within the cat's primary somatosensory cortex.
Topics: Animals; Anti-Anxiety Agents; Bicuculline; Cats; Diazepam; Electric Stimulation; Electrophysiology; Female; Flumazenil; Fluphenazine; gamma-Aminobutyric Acid; Male; Midazolam; Physical Stimulation; Somatosensory Cortex; Space Perception; Synapses | 1990 |
Attenuation of benzodiazepine-induced passive avoidance deficit by post-training administration of muscimol: interaction with the cholinergic neuronal system.
Topics: Animals; Anti-Anxiety Agents; Avoidance Learning; Bicuculline; Chlordiazepoxide; Flumazenil; Male; Mice; Mice, Inbred Strains; Muscimol; Neurons; Parasympathetic Nervous System; Receptors, Cholinergic; Receptors, GABA-A; Scopolamine | 1990 |
Relaxant effect of benzodiazepines on uterine rings isolated from estrogen-treated rats.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Bicuculline; Clonazepam; Convulsants; Diazepam; Estradiol; Estrogens; Female; Flumazenil; In Vitro Techniques; Isoquinolines; Muscle, Smooth; Potassium Chloride; Propranolol; Rats; Rats, Inbred Strains; Uterine Contraction | 1990 |
Effects of DM-9384, a pyrrolidone derivative, on alcohol- and chlordiazepoxide-induced amnesia in mice.
Topics: Amnesia; Animals; Avoidance Learning; Bicuculline; Central Nervous System Agents; Chlordiazepoxide; Drug Interactions; Ethanol; Flumazenil; Male; Mice; Pyrrolidinones; Retention, Psychology; Scopolamine | 1990 |
On the mechanism by which midazolam causes spinally mediated analgesia.
Topics: Analgesia, Epidural; Animals; Bicuculline; Cyclazocine; Dose-Response Relationship, Drug; Electric Stimulation; Ethylketocyclazocine; Fentanyl; Flumazenil; Male; Midazolam; Pain; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sensory Thresholds | 1990 |
The activity of zolpidem and other hypnotics within the gamma-aminobutyric acid (GABAA) receptor supramolecular complex, as determined by 35S-t-butylbicyclophosphorothionate (35S-TBPS) binding to rat cerebral cortex membranes.
Topics: Animals; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Hypnotics and Sedatives; In Vitro Techniques; Male; Pyridines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Zolpidem | 1990 |
Chloride channel modulation through the benzodiazepine recognition site.
Topics: Animals; Bicuculline; Carbolines; Cells, Cultured; Chlorides; Convulsants; Flumazenil; Flunitrazepam; Ion Channels; Neurons; Receptors, GABA-A | 1988 |
Patterns of convulsive susceptibility in the long-sleep and short-sleep selected mouse lines.
Topics: Animals; Anticonvulsants; Bicuculline; Convulsants; Female; Flumazenil; Male; Mice; Pentylenetetrazole; Phenobarbital; Reaction Time; Seizures; Sleep | 1989 |
Chlordiazepoxide and valproate enhancement of saline drinking by nondeprived rats: effects of bicuculline, picrotoxin and Ro15-1788.
Topics: Animals; Bicuculline; Chlordiazepoxide; Dose-Response Relationship, Drug; Drinking Behavior; Drug Combinations; Drug Interactions; Flumazenil; Male; Picrotoxin; Rats; Rats, Inbred Strains; Sodium Chloride; Valproic Acid | 1989 |
Locomotor effects of amperozide. Antagonism of amphetamine-induced locomotor stimulation.
Topics: Animals; Bicuculline; Dextroamphetamine; Dose-Response Relationship, Drug; Flumazenil; Male; Mice; Motor Activity; Piperazines; Psychotropic Drugs | 1989 |
Relationship of agonist efficacy to changes in GABA sensitivity and anticonvulsant tolerance following chronic benzodiazepine ligand exposure.
Topics: Animals; Anticonvulsants; Behavior, Animal; Benzodiazepines; Benzodiazepinones; Bicuculline; Brain Chemistry; Diazepam; Drug Tolerance; Electrophysiology; Flumazenil; gamma-Aminobutyric Acid; Male; Raphe Nuclei; Rats; Rats, Inbred Strains; Seizures | 1989 |
Does the PCPA induced anticonflict effect involve activation of the GABAA/benzodiazepine chloride ionophore receptor complex?
Topics: Animals; Anxiety; Bicuculline; Brain; Dose-Response Relationship, Drug; Fenclonine; Flumazenil; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin | 1989 |
Effects of amperozide in two animal models of anxiety.
Topics: Animals; Anti-Anxiety Agents; Bicuculline; Brain Chemistry; Conflict, Psychological; Disease Models, Animal; Drinking Behavior; Electroshock; Flumazenil; Male; Piperazines; Psychotropic Drugs; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1989 |
Behavioral analysis of zopiclone on the basis of their discriminative stimulus properties in the rat.
Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Behavior, Animal; Benzodiazepines; Bicuculline; Discrimination Learning; Dose-Response Relationship, Drug; Flumazenil; Hypnotics and Sedatives; Male; Muscimol; Naphthyridines; Pentylenetetrazole; Piperazines; Piperidines; Rats; Rats, Inbred WKY; Ritanserin; Serotonin Antagonists; Sulfur Compounds | 1989 |
Amelioration of hepatic encephalopathy by pharmacologic antagonism of the GABAA-benzodiazepine receptor complex in a rabbit model of fulminant hepatic failure.
Topics: Animals; Bicuculline; Evoked Potentials, Visual; Flumazenil; Hepatic Encephalopathy; Organophosphorus Compounds; Rabbits; Receptors, GABA-A; Synaptic Transmission | 1987 |
GABA-benzodiazepine modulation of aversion in the medial hypothalamus of the rat.
Topics: Animals; Avoidance Learning; Bicuculline; Dose-Response Relationship, Drug; Electric Stimulation; Electrodes, Implanted; Flumazenil; Hypothalamus, Middle; Isoxazoles; Male; Microinjections; Midazolam; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1987 |
Heterogeneity of gamma-aminobutyric acid/benzodiazepine/beta-carboline receptor complex in rat spinal cord.
Topics: Animals; Bicuculline; Binding, Competitive; Carbolines; Cerebellum; Diazepam; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Receptors, GABA-A; Spinal Cord; Synaptic Membranes | 1988 |
Osmotic shock: a method to eliminate endogenous gamma-aminobutyric acid and account for the influence on benzodiazepine binding affinity in autoradiographic studies.
Topics: Animals; Autoradiography; Benzodiazepines; Bicuculline; Binding Sites; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Male; Osmotic Pressure; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1988 |
Effects of drugs on the electrical activity of the red nucleus in the rabbit. Activation of benzodiazepine and barbiturate receptors.
Topics: Animals; Bicuculline; Carbolines; Diazepam; Drug Interactions; Electroencephalography; Flumazenil; Muscle Relaxation; Pentobarbital; Pyridazines; Rabbits; Receptors, GABA-A; Receptors, Neurotransmitter; Red Nucleus | 1988 |
Modulation of the GABA autoreceptor by benzodiazepine receptor ligands.
Topics: Animals; Bicuculline; Carbolines; Clonazepam; Flumazenil; Ligands; Male; Muscimol; Rats; Receptors, GABA-A | 1988 |
Drugs which stimulate or facilitate central GABAergic transmission interact synergistically with delta-9-tetrahydrocannabinol to produce marked catalepsy in mice.
Topics: Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Catalepsy; Dronabinol; Drug Synergism; Flumazenil; Flupenthixol; Flurazepam; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Nipecotic Acids; Receptors, GABA-A; Strychnine; Taurine; Tiagabine | 1988 |
[Antagonism of RO 15-1788 with benzodiazepines in the effect on motivated aggression and the action of analgesics].
Topics: Aggression; Analgesics; Animals; Anti-Anxiety Agents; Benzodiazepinones; Bicuculline; Electric Stimulation; Escape Reaction; Flumazenil; Humans; Male; Motivation; Rats; Receptors, GABA-A | 1985 |
[Mechanism of the tranquilizing action of electron structural analogs of nicotinamide].
Topics: Animals; Benzodiazepinones; Bicuculline; Brain; Conflict, Psychological; Flumazenil; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Inosine; Male; Niacinamide; Radioligand Assay; Rats; Receptors, GABA-A; Serotonin; Synaptosomes; Tranquilizing Agents; Valproic Acid | 1986 |
[Benzodiazepines and benzodiazepine receptors].
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Bicuculline; Brain; Flumazenil; gamma-Aminobutyric Acid; Mice; Muscle Relaxants, Central; Pyrazoles; Rats; Receptors, GABA-A; Receptors, Neurotransmitter; Synaptic Transmission | 1986 |
Functional coupling of gamma-aminobutyric acid (GABA)A and benzodiazepine type II receptors: analysis using purified GABA/benzodiazepine receptor complex from bovine cerebral cortex.
Topics: Animals; Antipsychotic Agents; Bicuculline; Cattle; Cerebral Cortex; Flumazenil; Flunitrazepam; In Vitro Techniques; Kinetics; Muscimol; Pyridazines; Receptors, GABA-A | 1987 |
Benzodiazepines increase tonic component of postdecapitation convulsions in mice.
Topics: Animals; Anti-Anxiety Agents; Bicuculline; Decerebrate State; Flumazenil; Male; Mice; Mice, Inbred Strains; Picrotoxin; Receptors, GABA-A; Seizures | 1988 |
Involvement of a GABAergic mechanism in the anticonvulsant effect of pentobarbital against maximal electroshock-induced seizures in rats.
Topics: Animals; Anticonvulsants; Benzodiazepinones; Bicuculline; Drug Interactions; Electroshock; Ethanol; Flumazenil; GABA Antagonists; gamma-Aminobutyric Acid; Male; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Sleep | 1985 |
Central effects of nicotinamide and inosine which are not mediated through benzodiazepine receptors.
Topics: Action Potentials; Animals; Benzodiazepinones; Bicuculline; Binding, Competitive; Brain; Chlordiazepoxide; Convulsants; Female; Flumazenil; Flunitrazepam; In Vitro Techniques; Inosine; Male; Membranes; Niacinamide; Purkinje Cells; Rats; Rats, Inbred Strains; Receptors, GABA-A; Social Behavior | 1985 |
Proconflict effect of GABA receptor complex antagonists. Reversal by diazepam.
Topics: Animals; Benzodiazepinones; Bicuculline; Conflict, Psychological; Diazepam; Flumazenil; Male; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1986 |
Benzodiazepines inhibit thyrotropin (TSH)-releasing hormone-induced TSH and growth hormone release from perifused rat pituitaries.
Topics: Animals; Benzodiazepines; Bicuculline; Diazepam; Flumazenil; Growth Hormone; Growth Hormone-Releasing Hormone; In Vitro Techniques; Isoquinolines; Male; Picrotoxin; Pituitary Gland, Anterior; Rats; Receptors, GABA-A; Secretory Rate; Thyrotropin; Thyrotropin-Releasing Hormone | 1986 |
Naloxone-sensitive and GABAA receptor mediated analgesic response of benzodiazepines in mice.
Topics: Analgesics; Animals; Benzodiazepines; Benzodiazepinones; Bicuculline; Female; Flumazenil; Male; Mice; Naloxone; Phenytoin; Reaction Time; Receptors, GABA-A | 1987 |
Reversal of the effect of centrally-administered diazepam on morphine antinociception by specific (Ro 15-1788 and Ro 15-3505) and non-specific (bicuculline and caffeine) benzodiazepine antagonists.
Topics: Animals; Benzodiazepinones; Bicuculline; Caffeine; Diazepam; Flumazenil; Injections, Intraventricular; Male; Morphine; Pain; Rats; Rats, Inbred Strains | 1986 |
Modulation of gamma-aminobutyric acid-mediated inhibitory synaptic currents in dissociated cortical cell cultures.
Topics: Animals; Bicuculline; Carbolines; Cells, Cultured; Cerebral Cortex; Electric Conductivity; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Membrane Potentials; Neural Inhibition; Rats; Synapses | 1986 |
Analgesic effects of the progesterone metabolite, 3 alpha-hydroxy-5 alpha-pregnan-20-one, and possible modes of action in mice.
Topics: Analgesics; Animals; Bicuculline; Brain; Calcium Channel Blockers; Flumazenil; Injections, Intraventricular; Male; Mice; Naloxone; Picrotoxin; Progesterone | 1987 |
Persistent reversal of tolerance to anticonvulsant effects and GABAergic subsensitivity by a single exposure to benzodiazepine antagonist during chronic benzodiazepine administration.
Topics: Animals; Behavior, Animal; Benzodiazepines; Bicuculline; Drug Tolerance; Flumazenil; gamma-Aminobutyric Acid; Iontophoresis; Male; Neurons; Raphe Nuclei; Rats; Rats, Inbred Strains; Seizures | 1988 |
Enhancement of a diazepam withdrawal symptom by bicuculline and yohimbine.
Topics: Animals; Bicuculline; Diazepam; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Flumazenil; Male; Rats; Substance Withdrawal Syndrome; Yohimbine | 1987 |
Neurosteroid pregnenolone sulfate antagonizes electrophysiological responses to GABA in neurons.
Topics: Action Potentials; Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Cerebral Cortex; Flumazenil; gamma-Aminobutyric Acid; Pentobarbital; Pregnenolone; Rats; Steroids | 1988 |
Analgesic effects of the putative FSH-suppressing gonadal steroid, 3 alpha-hydroxy-4-pregnen-20-one: possible modes of action.
Topics: 20-alpha-Dihydroprogesterone; Analgesia; Analgesics; Animals; Bicuculline; Calcium Channel Blockers; Cerebral Ventricles; Flumazenil; Follicle Stimulating Hormone; Injections, Intraventricular; Male; Mice; Naloxone; Progesterone; Reference Values | 1988 |
In vivo interactions between the benzodiazepine antagonist Ro 15-1788 and the steroid anaesthetic althesin in rats.
Topics: Alfaxalone Alfadolone Mixture; Anesthetics; Animals; Benzodiazepinones; Bicuculline; Drug Synergism; Drug Therapy, Combination; Female; Flumazenil; Pregnanediones; Rats; Rats, Inbred Strains; Seizures | 1985 |
Effects of aminophylline and 2-chloroadenosine on seizures produced by pilocarpine in rats: morphological and electroencephalographic correlates.
Topics: 2-Chloroadenosine; Adenosine; Aminophylline; Animals; Benzodiazepinones; Bicuculline; Brain; Carbolines; Convulsants; Electroencephalography; Flumazenil; Male; Motor Activity; Pilocarpine; Rats; Rats, Inbred Strains; Seizures | 1985 |
The effects of benzodiazepine agonists, inverse agonists and Ro 15-1788 on the responses of the superior cervical ganglion to GABA in vitro.
Topics: Animals; Barbiturates; Benzodiazepinones; Bicuculline; Carbolines; Chlordiazepoxide; Flumazenil; Flurazepam; gamma-Aminobutyric Acid; Ganglia, Sympathetic; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1984 |
The effects of GABA and benzodiazepine receptor antagonists on the anti-conflict actions of diazepam or ethanol.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Bicuculline; Conflict, Psychological; Diazepam; Dose-Response Relationship, Drug; Ethanol; Flumazenil; Male; Picrotoxin; Punishment; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1984 |
Self-injection of diazepam in naive rats: effects of dose, schedule and blockade of different receptors.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Bicuculline; Diazepam; Dose-Response Relationship, Drug; Extinction, Psychological; Flumazenil; Haloperidol; Male; Naloxone; Rats; Receptors, Drug; Reinforcement Schedule; Self Administration | 1984 |
Is the muscle relaxant effect of diazepam in spastic mutant rats mediated through GABA-independent benzodiazepine receptors?
Topics: Animals; Benzodiazepinones; Bicuculline; Diazepam; Electromyography; Female; Flumazenil; Male; Muscle Contraction; Muscle Relaxation; Picrotoxin; Rats; Rats, Mutant Strains; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Is Ro15-1788 a partial agonist at benzodiazepine receptors?
Topics: Animals; Benzodiazepinones; Bicuculline; Convulsants; Diazepam; Flumazenil; Male; Mice; Mice, Inbred C3H; Phenobarbital; Pyridazines; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Diazepam, pentobarbital and D-etomidate produced increases in bicuculline seizure threshold; selective antagonism by RO15-1788, picrotoxin and (+/-)-DMBB.
Topics: Animals; Barbiturates; Benzodiazepinones; Bicuculline; Diazepam; Etomidate; Flumazenil; Imidazoles; Male; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Seizures | 1983 |
Reversal of the anti-conflict action of valproate by various GABA and benzodiazepine antagonists.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Bicuculline; Conflict, Psychological; Flumazenil; GABA Antagonists; Male; Motor Activity; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Valproic Acid | 1984 |
RO5-4864 inhibits the binding of [35S]t-butylbicyclophosphorothionate to rat brain membranes.
Topics: Androstanes; Animals; Azasteroids; Benzodiazepinones; Bicuculline; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Carbolines; Cell Membrane; Cerebellum; Cerebral Cortex; Dose-Response Relationship, Drug; Flumazenil; Hippocampus; Male; Picrotoxin; Radioligand Assay; Rats | 1984 |
Effects of benzodiazepines on single unit activity in the substantia nigra pars reticulata.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Bicuculline; Caffeine; Diazepam; Dose-Response Relationship, Drug; Electric Conductivity; Flumazenil; Flurazepam; Male; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Substantia Nigra; Theophylline | 1982 |
Effect of the benzodiazepine receptor antagonist Ro 15-1788 on the anticonvulsant and anticonflict actions of MK-801.
Topics: Animals; Anticonvulsants; Behavior, Animal; Benzodiazepinones; Bicuculline; Chlordiazepoxide; Clonazepam; Conflict, Psychological; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Interactions; Female; Flumazenil; Mice; Phenobarbital; Rats; Rats, Inbred Strains | 1982 |
The benzodiazepine antagonist, Ro 15-1788, prevents the effects of flurazepam on the high pressure neurological syndrome.
Topics: Animals; Benzodiazepinones; Bicuculline; Flumazenil; Flurazepam; Male; Mice; Nervous System Diseases; Pressure; Seizures; Tremor | 1982 |
Role of GABAergic systems in the development of morphine tolerance in formalin-treated mice.
Topics: Analgesics, Opioid; Animals; Baclofen; Bicuculline; Diazepam; Drug Tolerance; Flumazenil; Formaldehyde; GABA Agonists; GABA Antagonists; Male; Mice; Mice, Inbred Strains; Morphine; Muscimol; Pain; Pain Measurement; Receptors, GABA | 1995 |
Decreased predator avoidance in parasitized mice: neuromodulatory correlates.
Topics: Animals; Anxiety; Avoidance Learning; Bicuculline; Cats; Coccidiosis; Dizocilpine Maleate; Eimeria; Flumazenil; GABA Antagonists; GABA-A Receptor Antagonists; Male; Mice; N-Methylaspartate; Naloxone; Odorants; Picrotoxin; Predatory Behavior; Receptors, GABA-A | 1995 |
Involvement of benzodiazepine/GABA-A receptor complex in ethanol-induced state-dependent learning in rats.
Topics: Animals; Avoidance Learning; Azides; Benzodiazepines; Bicuculline; Diazepam; Ethanol; Evaluation Studies as Topic; Flumazenil; Male; Muscimol; Picrotoxin; Rats; Rats, Wistar; Reaction Time; Receptors, GABA-A | 1995 |
Central-type benzodiazepine receptors mediate the antidopaminergic effect of clonazepam and melatonin in 6-hydroxydopamine lesioned rats: involvement of a GABAergic mechanism.
Topics: Animals; Apomorphine; Behavior, Animal; Bicuculline; Clonazepam; Corpus Striatum; Dopamine Agonists; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Isoquinolines; Male; Melatonin; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1995 |
Effect of Leu-enkephalin on the memory reactivation produced by blockade of the benzodiazepine/GABA-chloride ionophore receptor complex.
Topics: Analysis of Variance; Animals; Avoidance Learning; Bicuculline; Enkephalin, Leucine; Flumazenil; GABA-A Receptor Antagonists; Male; Memory Disorders; Mice; Mice, Inbred BALB C; Picrotoxin; Receptors, Opioid, delta | 1995 |
Anxiolytic effects of chlordiazepoxide blocked by injection of GABAA and benzodiazepine receptor antagonists in the region of the anterior basolateral amygdala of rats.
Topics: Amygdala; Animals; Arousal; Bicuculline; Brain Mapping; Chlordiazepoxide; Flumazenil; GABA-A Receptor Antagonists; Male; Rats; Rats, Wistar; Receptors, GABA-A; Social Behavior | 1995 |
Repeated treatment with alpidem, a new anxiolytic, does not induce tolerance or physical dependence.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Bicuculline; Carbolines; Convulsants; Diazepam; Drug Tolerance; Flumazenil; Imidazoles; Isoniazid; Male; Mice; Pentylenetetrazole; Pyridines; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders | 1993 |
Interaction between benzodiazepine and GABA-A receptors in state-dependent learning.
Topics: Animals; Avoidance Learning; Baclofen; Bicuculline; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Male; Muscimol; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Reference Values | 1993 |
Inhibitory effect of diazepam on the activity of the hypothalamic-pituitary-adrenal axis in female rats.
Topics: Adrenocorticotropic Hormone; Animals; Bicuculline; Corticosterone; Depression, Chemical; Diazepam; Female; Flumazenil; GABA-A Receptor Antagonists; Hypothalamo-Hypophyseal System; Isoquinolines; Picrotoxin; Pituitary-Adrenal System; Rats; Receptors, GABA-A | 1993 |
Lack of anticonvulsant tolerance and benzodiazepine receptor down regulation with imidazenil in rats.
Topics: Animals; Anticonvulsants; Benzodiazepines; Bicuculline; Diazepam; Down-Regulation; Drug Tolerance; Flumazenil; GABA Modulators; Imidazoles; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures; Tritium | 1996 |
Anticonvulsant profile of the imidazoquinazolines NNC 14-0185 and NNC 14-0189 in rats and mice.
Topics: Acoustic Stimulation; Amygdala; Animals; Anticonvulsants; Bicuculline; Carbolines; Clonazepam; Diazepam; Electroshock; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; Kindling, Neurologic; Male; Mice; Mice, Inbred DBA; Mice, Inbred Strains; Pentylenetetrazole; Quinazolines; Rats; Rats, Wistar; Seizures | 1996 |
Synergistic interactions between midazolam and alfentanil in isolated neonatal rat spinal cord.
Topics: Alfentanil; Analgesics, Opioid; Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Synergism; Evoked Potentials; Flumazenil; Hypnotics and Sedatives; Midazolam; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Spinal Cord | 1996 |
Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit.
Topics: Amino Acid Sequence; Anesthetics, Intravenous; Animals; Bicuculline; Brain; Cell Line; Consensus Sequence; DNA, Complementary; Flumazenil; Flunitrazepam; GABA Agents; gamma-Aminobutyric Acid; Humans; Molecular Sequence Data; Muscimol; Pentobarbital; Picrotoxin; Pregnanolone; Propofol; Rats; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Transfection | 1997 |
Sex differences in bicuculline-induced convulsions: interaction with stress and ligands of benzodiazepine binding sites.
Topics: Animals; Benzodiazepines; Bicuculline; Binding Sites; Cold Temperature; Diazepam; Differential Threshold; Dose-Response Relationship, Drug; Female; Flumazenil; Handling, Psychological; Ligands; Male; Rats; Rats, Wistar; Seizures; Sex Characteristics; Stress, Physiological; Swimming | 1997 |
The antidopaminergic action of S-20098 is mediated by benzodiazepine/GABA(A) receptors in the striatum.
Topics: Acetamides; Animals; Bicuculline; Corpus Striatum; Dopamine Antagonists; Flumazenil; GABA Antagonists; GABA Modulators; Injections; Injections, Intraperitoneal; Male; Melatonin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1997 |
[The effects of flumazenil or bicuculline on the respiratory depression by morphine].
Topics: Action Potentials; Animals; Bicuculline; Depression, Chemical; Flumazenil; GABA Antagonists; GABA Modulators; Morphine; Naloxone; Narcotic Antagonists; Phrenic Nerve; Rats; Respiration; Respiratory Insufficiency | 1998 |
Modification of the anxiolytic action of 5-HT1A compounds by GABA-benzodiazepine agents in rats.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Anxiety; Bicuculline; Buspirone; Diazepam; Drug Interactions; Flumazenil; GABA Agonists; Male; Psychomotor Performance; Pyrimidines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1 | 1998 |
Behavioural pharmacological characteristics of honokiol, an anxiolytic agent present in extracts of Magnolia bark, evaluated by an elevated plus-maze test in mice.
Topics: Administration, Oral; Animals; Anti-Anxiety Agents; Bicuculline; Biphenyl Compounds; Caffeine; Central Nervous System Depressants; Central Nervous System Stimulants; Diazepam; Dose-Response Relationship, Drug; Flumazenil; GABA Antagonists; GABA Modulators; Injections, Subcutaneous; Lignans; Male; Maze Learning; Mice; Mice, Inbred BALB C; Motor Activity; Tetragastrin; Therapeutic Equivalency | 1998 |
Differential interaction between 5-HT3 receptors and GABAergic neurons inhibiting acetylcholine release in rat entorhinal cortex slices.
Topics: Acetylcholine; Animals; Barium; Bicuculline; Chloride Channels; Culture Techniques; Entorhinal Cortex; Flumazenil; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Neurons; Ondansetron; Perfusion; Potassium Channel Blockers; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Tetraethylammonium; Tropanes | 1998 |
Abecarnil enhances recovery from diazepam tolerance.
Topics: Animals; Anticonvulsants; Benzodiazepines; Bicuculline; Carbolines; Cell Membrane; Cerebral Cortex; Clonazepam; Diazepam; Drug Interactions; Drug Tolerance; Flumazenil; Imidazoles; Ligands; Male; Mice; Receptors, GABA-A; Seizures; Tritium | 1999 |
Role of the conserved lysine residue in the middle of the predicted extracellular loop between M2 and M3 in the GABA(A) receptor.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Bicuculline; Binding, Competitive; Cell Line; Conserved Sequence; Female; Flumazenil; gamma-Aminobutyric Acid; Humans; Kinetics; Lysine; Muscimol; Mutagenesis, Site-Directed; Oocytes; Protein Structure, Secondary; Radioligand Assay; Rats; Receptors, GABA-A; Recombinant Proteins; Sequence Alignment; Transfection; Xenopus laevis | 1999 |
The role of the benzodiazepine-GABA system in the memory processes of the day-old chick.
Topics: Animals; Animals, Newborn; Bicuculline; Chickens; Diazepam; Discrimination, Psychological; Flumazenil; GABA Antagonists; GABA Modulators; Male; Memory; Receptors, GABA-A; Reinforcement, Psychology | 2000 |
Modulation of GABAergic synaptic transmission by the non-benzodiazepine anxiolytic etifoxine.
Topics: Animals; Behavior, Animal; Bicuculline; Binding, Competitive; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Dose-Response Relationship, Drug; Drinking Behavior; Flumazenil; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Isoquinolines; Male; Membrane Potentials; Membranes; Neurons; Oxazines; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, GABA-A; Sulfur Radioisotopes; Synaptic Transmission; Tetrodotoxin; Tranquilizing Agents | 2000 |
Benzodiazepine-sensitive GABA(A) receptors limit the activity of the NMDA/NO/cyclic GMP pathway: a microdialysis study in the cerebellum of freely moving rats.
Topics: Animals; Anti-Anxiety Agents; Bicuculline; Cerebellum; Cyclic GMP; Diazepam; Flumazenil; Infusions, Parenteral; Kinetics; Male; Microdialysis; Muscimol; N-Methylaspartate; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Zolpidem | 2000 |
Anti-depressant action of melatonin in chronic forced swimming-induced behavioral despair in mice, role of peripheral benzodiazepine receptor modulation.
Topics: Alprazolam; Analysis of Variance; Animals; Anti-Anxiety Agents; Antioxidants; Benzodiazepinones; Bicuculline; Convulsants; Depression; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Flumazenil; GABA Agents; Immobilization; Isoquinolines; Male; Melatonin; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Receptors, GABA-A; Swimming; Time Factors | 2000 |
The influences of extremely low frequency magnetic fields on clonidine-induced sleep in 2-day-old chicks.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Animals, Newborn; Bicuculline; Brain Chemistry; Chickens; Chromatography, High Pressure Liquid; Clonidine; Dose-Response Relationship, Drug; Electrochemistry; Electromagnetic Fields; Flumazenil; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Norepinephrine; Sleep; Tyrosine | 2001 |
Role of benzodiazepine-GABAA receptor complex in attenuation of U-50,488H-induced analgesia and inhibition of tolerance to its analgesia by ginseng total saponin in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Animals; Bicuculline; Diazepam; Dose-Response Relationship, Drug; Drug Antagonism; Drug Tolerance; Drugs, Chinese Herbal; Flumazenil; Ginsenosides; Injections, Intraperitoneal; Male; Mice; Pain; Pain Threshold; Panax; Picrotoxin; Receptors, GABA-A; Receptors, Opioid, kappa; Saponins; Tail | 2002 |
Effects of striatal injections of GABA(A) receptor agonists and antagonists in a genetic animal model of paroxysmal dystonia.
Topics: Animals; Bicuculline; Binding Sites; Corpus Striatum; Cricetinae; Dystonia; Female; Flumazenil; Flurazepam; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Male; Mesocricetus; Microinjections; Muscimol; Pentylenetetrazole; Phenobarbital | 2002 |
Effects of GABA(A) compounds on mCPP drug discrimination in rats.
Topics: Alprazolam; Animals; Azides; Benzodiazepines; Bicuculline; Conditioning, Operant; Discrimination, Psychological; Flumazenil; GABA Agonists; GABA Antagonists; Male; Pentylenetetrazole; Piperazines; Rats; Rats, Long-Evans; Receptors, GABA-A | 2002 |
GABA(A) receptor antagonists enhance cortical acetylcholine release induced by 5-HT(3) receptor blockade in freely moving rats.
Topics: Acetylcholine; Animals; Bicuculline; Drug Synergism; Flumazenil; Frontal Lobe; GABA Antagonists; GABA-A Receptor Antagonists; Male; Microdialysis; Movement; Ondansetron; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists | 2002 |
Inhibitory effect of propofol on ketamine-induced c-Fos expression in the rat posterior cingulate and retrosplenial cortices is mediated by GABAA receptor activation.
Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Animals; Bicuculline; Cerebral Cortex; Electroencephalography; Excitatory Amino Acid Antagonists; Flumazenil; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; Gene Expression Regulation; Genes, fos; Gyrus Cinguli; Hemodynamics; Image Processing, Computer-Assisted; Immunohistochemistry; Ketamine; Male; Propofol; Rats; Rats, Wistar | 2003 |
Anti-conflict-like actions of intralateral septal infusions of allopregnanolone in Wistar rats.
Topics: Animals; Behavior, Animal; Bicuculline; Conflict, Psychological; Dose-Response Relationship, Drug; Female; Flumazenil; Functional Laterality; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Gonadal Steroid Hormones; Ovariectomy; Pregnanolone; Rats; Rats, Wistar; Septum of Brain; Stereotaxic Techniques | 2003 |
Anticonvulsant and antiepileptogenic effects of GABAA receptor ligands in pentylenetetrazole-kindled mice.
Topics: Animals; Anticonvulsants; Bicuculline; Convulsants; Dehydroepiandrosterone Sulfate; Diazepam; Dose-Response Relationship, Drug; Epilepsy; Flumazenil; GABA Agonists; GABA Antagonists; GABA Modulators; Isoxazoles; Kindling, Neurologic; Ligands; Mice; Pentylenetetrazole; Pregnanediones; Receptors, GABA-A | 2004 |
Benzodiazepine system is involved in hyperalgesia in rats induced by the exposure to extremely low frequency magnetic fields.
Topics: Animals; Anti-Anxiety Agents; Baclofen; Bicuculline; Diazepam; Electromagnetic Fields; Flumazenil; GABA Antagonists; GABA Modulators; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Hot Temperature; Hyperalgesia; Injections, Intraventricular; Male; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, GABA-A | 2005 |
Novel plant substances acting as beta subunit isoform-selective positive allosteric modulators of GABAA receptors.
Topics: Allosteric Regulation; Animals; Araliaceae; Bicuculline; Flumazenil; Flunitrazepam; GABA Modulators; Picrotoxin; Plant Extracts; Receptors, GABA-A; Xenopus laevis | 2005 |
Resuscitative effect of a gamma-aminobutyric acid B receptor antagonist on gamma-hydroxybutyric acid mortality in mice.
Topics: Animals; Benzocycloheptenes; Bicuculline; Drug Overdose; Flumazenil; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Morpholines; Naltrexone; Neuroprotective Agents; Neurotransmitter Agents; Survival Rate; Taurine | 2005 |
Involvement of diazepam-insensitive benzodiazepine receptors in the suppression of DOI-induced head-twitch responses in diabetic mice.
Topics: Amphetamines; Animals; Azides; Behavior, Animal; Benzodiazepines; Bicuculline; Diabetes Mellitus, Experimental; Diazepam; Flumazenil; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Male; Mice; Mice, Inbred ICR; Receptors, GABA-A; Serotonin Receptor Agonists | 2006 |
Involvement of 5-HT1A and GABAA receptors in the anxiolytic-like effects of Cinnamomum cassia in mice.
Topics: Animals; Anti-Anxiety Agents; Bicuculline; Cinnamomum; Ethanol; Flumazenil; GABA Antagonists; GABA Modulators; Male; Mice; Mice, Inbred ICR; Motor Activity; Muscle Relaxants, Central; Piperazines; Plant Extracts; Postural Balance; Pyridines; Receptor, Serotonin, 5-HT1A; Receptors, GABA-A; Serotonin Antagonists; Solvents | 2007 |
Anxiolytic-like effects of sinapic acid in mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Bicuculline; Cerebral Cortex; Chloride Channels; Coumaric Acids; Diazepam; Electrophysiology; Flumazenil; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred ICR; Motor Activity; Muscle Relaxation; Muscle, Smooth; Neurons; Neurotransmitter Agents; Piperazines; Postural Balance; Pyridines; Serotonin Antagonists | 2007 |
Central PGE2 exhibits anxiolytic-like activity via EP1 and EP4 receptors in a manner dependent on serotonin 5-HT1A, dopamine D1 and GABAA receptors.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Benzazepines; Bicuculline; Brain; Dinoprostone; Flumazenil; GABA Modulators; GABA-A Receptor Antagonists; Male; Mice; Mice, Knockout; Neuropsychological Tests; Piperazines; Receptor, Serotonin, 5-HT1A; Receptors, Dopamine D1; Receptors, GABA-A; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Serotonin Antagonists | 2011 |
Yokukansan enhances pentobarbital-induced sleep in socially isolated mice: possible involvement of GABA(A)-benzodiazepine receptor complex.
Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Synergism; Drugs, Chinese Herbal; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Hypnotics and Sedatives; Male; Medicine, Kampo; Mice; Mice, Inbred Strains; Pentobarbital; Receptors, GABA-A; Sleep; Sleep Wake Disorders; Social Isolation; Stress, Psychological | 2011 |
Anti-stress effects of 20(S)-protopanaxadiol and 20(S)-protopanaxatriol in immobilized mice.
Topics: Animals; Anti-Anxiety Agents; Anti-Inflammatory Agents; Bicuculline; Corticosterone; Flumazenil; GABA Modulators; GABA-A Receptor Antagonists; Interleukin-6; Male; Mice, Inbred ICR; Piperazines; Pyridines; Receptors, GABA-A; Receptors, Serotonin; Restraint, Physical; Sapogenins; Serotonin Antagonists; Stress, Psychological | 2015 |
The non-benzodiazepine anxiolytic drug etifoxine causes a rapid, receptor-independent stimulation of neurosteroid biosynthesis.
Topics: 17-alpha-Hydroxypregnenolone; 20-alpha-Dihydroprogesterone; Animals; Anti-Anxiety Agents; Bicuculline; Complex Mixtures; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Flumazenil; GABA Modulators; GABA-A Receptor Antagonists; Gene Expression; Hypothalamus; Isoquinolines; Male; Neuropeptides; Oxazines; Peptide Fragments; Pregnanolone; Progesterone; Rana esculenta; Receptors, GABA-A; Tissue Culture Techniques | 2015 |
Bud extracts from Tilia tomentosa Moench inhibit hippocampal neuronal firing through GABAA and benzodiazepine receptors activation.
Topics: Animals; Anti-Anxiety Agents; Bicuculline; Dose-Response Relationship, Drug; Flumazenil; gamma-Aminobutyric Acid; Hippocampus; Hypnotics and Sedatives; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Picrotoxin; Plant Extracts; Receptors, GABA-A; Tilia | 2015 |
Kamishoyosan reduces conditioned fear-induced freezing behavior in socially isolated ovariectomized rats.
Topics: Animals; Bicuculline; Conditioning, Psychological; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Fear; Female; Flumazenil; Herb-Drug Interactions; Immobility Response, Tonic; Ovariectomy; Rats; Social Isolation | 2016 |
Effects of GABAa receptor antagonists on motor behavior in pharmacological Parkinson's disease model in mice.
Topics: Animals; Behavior, Animal; Bicuculline; Disease Models, Animal; Flumazenil; GABA-A Receptor Antagonists; Gait; Mice; Motor Activity; Parkinsonian Disorders | 2017 |
Anticonvulsant effects of Senna spectabilis on seizures induced by chemicals and maximal electroshock.
Topics: Animals; Anticonvulsants; Bicuculline; Convulsants; Electric Stimulation; Flumazenil; Male; Mice; Pentylenetetrazole; Pilocarpine; Plant Extracts; Plant Leaves; Plants, Medicinal; Random Allocation; Seizures; Senna Plant | 2018 |
Structure of a human synaptic GABA
Topics: Benzodiazepines; Bicuculline; Binding, Competitive; Brain Chemistry; Cell Membrane; Cryoelectron Microscopy; Flumazenil; GABA Modulators; gamma-Aminobutyric Acid; Glycosylation; HEK293 Cells; Humans; Immunoglobulin Fab Fragments; Ligands; Models, Molecular; Receptors, GABA-A | 2018 |
Anticonvulsant, Anxiolytic and Antidepressant Properties of the β-caryophyllene in Swiss Mice: Involvement of Benzodiazepine-GABAAergic, Serotonergic and Nitrergic Systems.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents; Arginine; Behavior, Animal; Benzodiazepines; Bicuculline; Female; Flumazenil; GABA-A Receptor Antagonists; Humans; Maze Learning; Mice; Nitric Oxide; Polycyclic Sesquiterpenes; Receptors, GABA-A; Seizures; Signal Transduction | 2021 |
Shared structural mechanisms of general anaesthetics and benzodiazepines.
Topics: Allosteric Regulation; Anesthetics, General; Barbiturates; Benzodiazepines; Bicuculline; Binding Sites; Binding, Competitive; Cryoelectron Microscopy; Diazepam; Electrophysiology; Etomidate; Flumazenil; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Ligands; Models, Molecular; Molecular Conformation; Molecular Dynamics Simulation; Phenobarbital; Picrotoxin; Propofol; Receptors, GABA-A | 2020 |
Bumetanide prevents diazepam-modified anxiety-like behavior in lipopolysaccharide-treated mice.
Topics: Animals; Anti-Anxiety Agents; Anti-Bacterial Agents; Anxiety; Behavior, Animal; Bicuculline; Bumetanide; Diazepam; Emotions; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Inflammation; Lipopolysaccharides; Male; Mice, Inbred ICR; Minocycline; Motor Activity; Sodium Potassium Chloride Symporter Inhibitors | 2021 |
Inhibition of GABAA receptors in intestinal stem cells prevents chemoradiotherapy-induced intestinal toxicity.
Topics: Animals; Bicuculline; Calcium; Chemoradiotherapy; Flumazenil; gamma-Aminobutyric Acid; Humans; Intestines; Mice; Reactive Oxygen Species; Receptors, GABA-A; Stem Cells; Tumor Suppressor Protein p53; United States | 2022 |
Zerumbone, a major sesquiterpene from Syringa pinnatifolia Hemsl., exerts the sedative effect by regulating GABAergic nervous system.
Topics: Animals; Bicuculline; Chlorides; Flumazenil; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Mice; Molecular Docking Simulation; Nervous System; Pentobarbital; Plant Extracts; Rats; Receptors, GABA-A; Sesquiterpenes; Syringa | 2023 |