flumazenil has been researched along with beta-carboline-3-carboxylic acid ethyl ester in 75 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 54 (72.00) | 18.7374 |
| 1990's | 13 (17.33) | 18.2507 |
| 2000's | 4 (5.33) | 29.6817 |
| 2010's | 4 (5.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Catarzi, D; Cecchi, L; Colotta, V; Costagli, C; Filacchioni, G; Galli, A; Varano, F | 1 |
| Cook, JM; Dayer, CA; He, X; Huang, Q; Liu, R; Ma, C; McKernan, R; Wenger, GR; Yu, S | 1 |
| Clayton, T; Cook, J; DeLorey, TM; Furtmüller, R; Halliwell, RF; Harris, D; Huck, S; Sahbaie, P; Sieghart, W | 1 |
| Clayton, T; Cook, JM; Cromer, BA; Ma, C; Majumder, S; Namjoshi, OA; Petrou, S; Platt, DM; Roth, BL; VanLinn, ML; Yin, W | 1 |
| Anzini, M; Betti, L; Biggio, G; Braile, C; Cappelli, A; Castriconi, F; Di Capua, A; Di Cesare Mannelli, L; Frosini, M; Ghelardini, C; Giannaccini, G; Giorgi, G; Giuliani, G; Grisci, G; Lucacchini, A; Mascia, MP; Paolino, M; Ricci, L; Valenti, S; Vomero, S | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Allen, MS; Barrett, JE; Cook, JM; Katz, JL; Takada, K | 1 |
| Allen, M; Cook, JM; Griffiths, RR; Sannerud, CA | 1 |
| Blakeman, DP; Im, WB | 1 |
| Morse, WH; Teeple, ES; Wettstein, JG | 2 |
| Cook, JM; Hagen, T; Katz, JL; Suzuki, T; Takada, K | 1 |
| DiMicco, JA; Hingtgen, JN; Shekhar, A | 1 |
| Ida, Y; Nishimura, H; Tanaka, M; Tsuda, A | 1 |
| Kaneto, H; Takahashi, M; Tokuyama, S | 1 |
| Cook, JM; Griffiths, RR; Sannerud, CA | 1 |
| Akaike, N; Fukuda, T; Oyama, Y; Yakushiji, T | 1 |
| Mos, J; Olivier, B; van der Poel, AM | 1 |
| Arbilla, S; Langer, SZ; Lista, A | 1 |
| File, SE | 1 |
| Barrett, JE; Brady, LS; Mansbach, RS; Stanley, JA; Witkin, JM | 1 |
| Cook, J; Larscheid, P; Takada, K; Winger, GD; Woods, JH | 1 |
| Dubroeucq, MC; Gauthier, A; Guérémy, C; Le Fur, G; Mizoule, J; Renault, C; Uzan, A | 1 |
| Böke-Kuhn, K; Danneberg, PB; Hommer, D; Kuhn, FJ; Lehr, E; Paul, SM; Skolnick, P; Weber, KH | 1 |
| Kempner, ES; Paul, SM; Schwartz, RD; Skolnick, P; Thomas, JW | 1 |
| Moura, D; Soares-da-Silva, P | 1 |
| Consolo, S; Forloni, G; Garattini, S; Kolasa, K; Ladinsky, H | 1 |
| Caporali, MG; Gatta, F; Lucantoni, D; Massotti, M; Mele, L | 1 |
| Hammond, JR | 1 |
| Paul, SM; Reed, GF; Skolnick, P | 1 |
| Cole, R; De Vellis, J; Noble, EP; Syapin, PJ | 1 |
| Cohen, RM; Havoundjian, H; Paul, SM; Skolnick, P | 1 |
| Cook, J; Larscheid, P; Takada, K; Winger, G; Woods, JH | 1 |
| Barrett, JE; Cook, JM; Larscheid, P; Witkin, JM | 1 |
| Glowa, JR; Paul, SM; Skolnick, P | 1 |
| Ciuffi, M; Franchi-Micheli, S; Luzzi, S; Rosi, E; Spagnesi, S; Zilletti, L | 1 |
| Biry, P; Pieri, L | 1 |
| File, SE; Pellow, S | 2 |
| Baldino, F; Geller, HM; Krespan, B | 1 |
| Kawasaki, K; Kodama, M; Matsushita, A | 1 |
| Little, HJ | 1 |
| Mendelson, WB | 1 |
| Moncada, VY; Paul, SM; Schweri, MM; Skolnick, P; Williams, EF | 1 |
| Bonetti, EP; Haefely, W; Polc, P; Schaffner, R | 1 |
| Nutt, D | 1 |
| Haefely, W | 2 |
| Cowen, PJ; Little, HJ; Nutt, DJ | 1 |
| File, SE; Lister, RG; Nutt, DJ | 2 |
| Cohen, RM; Cook, JM; Insel, TM; Ninan, PT; Paul, SM; Skolnick, P | 1 |
| Vellucci, SV; Webster, RA | 1 |
| De Robertis, E; Medina, JH; Novas, ML | 1 |
| Koe, BK; Lebel, LA | 1 |
| File, SE; Lister, RG | 1 |
| Paul, SM; Skolnick, P | 1 |
| Corda, MG; Costa, E; Guidotti, A | 1 |
| Garattini, S; Mennini, T | 1 |
| Brown, CL; Martin, IL | 1 |
| Braestrup, C; Honoré, T; Jensen, LH; Nielsen, M; Petersen, EN | 1 |
| Barrett, JE; Mansbach, RS; Stanley, JA | 1 |
| Coffin, VL; Phillis, JW; Wu, PH | 1 |
| Minchin, MC; Nutt, DJ | 1 |
| Ramanjaneyulu, R; Ticku, MK | 1 |
| Kanayama, T; Kobayashi, M; Koshikawa, N; Murai, T; Takada, K; Tomiyama, K | 1 |
| Kawasaki, K; Matsushita, A; Satoh, M; Yasui, M | 1 |
| Jun, X; Katsura, M; Kuriyama, K; Ohkuma, S | 1 |
| Auta, J; Faust, WB; Lambert, P; Moerschbaecher, JM; Winsauer, PJ | 1 |
| Hosoi, R; Inoue, O; Kobayashi, K; Watanabe, Y | 1 |
| Rowlett, JK; Wilcox, KM; Woolverton, WL | 1 |
| France, CP; Gerak, LR | 1 |
| France, CP; Gerak, LR; Lelas, S | 1 |
| Akabas, MH; Williams, DB | 1 |
| Abe, K; Hosoi, R; Inoue, O; Momosaki, S | 1 |
5 review(s) available for flumazenil and beta-carboline-3-carboxylic acid ethyl ester
| Article | Year |
|---|---|
What can be learned from the effects of benzodiazepines on exploratory behavior?
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Carbolines; Environment; Exploratory Behavior; Flumazenil; Lorazepam; Mice; Motor Activity; Pyrazoles; Rats; Receptors, GABA-A | 1985 |
[Drug activation of GABAergic transmission in the central nervous system: benzodiazepines and GABAergic agonists].
Topics: Animals; Benzodiazepines; Benzodiazepinones; Brain; Carbolines; Chemical Phenomena; Chemistry; Cyclic GMP; Diazepam; Flumazenil; gamma-Aminobutyric Acid; Humans; Receptors, GABA-A; Synaptic Transmission; Valproic Acid | 1985 |
Multiple sites of action for anxiogenic drugs: behavioural, electrophysiological and biochemical correlations.
Topics: Action Potentials; Animals; Anxiety; Behavior, Animal; Benzodiazepinones; Binding Sites; Brain Chemistry; Carbolines; Cats; Flumazenil; Humans; Mice; Rats; Receptors, GABA-A | 1984 |
Antagonists of benzodiazepines.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Binding, Competitive; Carbolines; Flumazenil; gamma-Aminobutyric Acid; Humans; Models, Chemical; Molecular Conformation; Pyrazoles; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter; Synaptic Transmission | 1983 |
On a brain polypeptide functioning as a putative effector for the recognition sites of benzodiazepine and beta-carboline derivatives.
Topics: Animals; Benzodiazepinones; Brain Chemistry; Carbolines; Carrier Proteins; Chlorides; Flumazenil; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Humans; Ionophores; Ligands; Membrane Proteins; Membrane Transport Proteins; Nerve Tissue Proteins; Organic Anion Transporters; Peptides; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
70 other study(ies) available for flumazenil and beta-carboline-3-carboxylic acid ethyl ester
| Article | Year |
|---|---|
Synthesis and binding activity of some pyrazolo[1,5-c]quinazolines as tools to verify an optional binding site of a benzodiazepine receptor ligand.
Topics: Animals; Binding Sites; Flunitrazepam; Hydrogen Bonding; Male; Pyrazoles; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Structure-Activity Relationship; Tritium | 1996 |
Pharmacophore/receptor models for GABA(A)/BzR subtypes (alpha1beta3gamma2, alpha5beta3gamma2, and alpha6beta3gamma2) via a comprehensive ligand-mapping approach.
Topics: Animals; Benzodiazepines; Carbolines; Cell Line; Columbidae; Conditioning, Operant; Crystallography, X-Ray; Humans; Indoles; Ligands; Male; Models, Molecular; Pyrimidines; Quinolones; Radioligand Assay; Receptors, GABA-A; Saimiri; Stereoisomerism; Structure-Activity Relationship | 2000 |
Selective influence on contextual memory: physiochemical properties associated with selectivity of benzodiazepine ligands at GABAA receptors containing the alpha5 subunit.
Topics: Animals; Behavior, Animal; Benzodiazepines; Chemical Phenomena; Chemistry, Physical; Computer Simulation; Databases, Factual; Electrophysiology; Female; Ligands; Male; Memory; Mice; Models, Molecular; Molecular Structure; Oocytes; Protein Isoforms; Protein Subunits; Quantitative Structure-Activity Relationship; Receptors, GABA-A; Structure-Activity Relationship; Xenopus laevis | 2008 |
Design, synthesis, and subtype selectivity of 3,6-disubstituted β-carbolines at Bz/GABA(A)ergic receptors. SAR and studies directed toward agents for treatment of alcohol abuse.
Topics: Alcoholism; Animals; Benzodiazepines; Binding Sites; Carbolines; Cell Line; Computer Simulation; GABA-A Receptor Antagonists; Humans; Protein Subunits; Rats; Receptors, GABA-A; Stereoisomerism; Structure-Activity Relationship | 2010 |
Design, Synthesis, and Biological Evaluation of Imidazo[1,5-a]quinoline as Highly Potent Ligands of Central Benzodiazepine Receptors.
Topics: Amnesia; Animals; Anti-Anxiety Agents; Behavior, Animal; Benzodiazepines; Binding Sites; Brain; Cattle; Drug Design; Humans; Ischemia; Ligands; Male; Mice; Models, Molecular; Neuroprotective Agents; Quinolines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Structure-Activity Relationship; Synaptosomes | 2016 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Punishment of schedule-controlled behavior with beta-carboline injections: antagonism and comparisons with other compounds.
Topics: Animals; Behavior, Animal; Carbolines; Conditioning, Operant; Electroshock; Flumazenil; Histamine; Injections, Intravenous; Male; Punishment; Saimiri | 1992 |
Behavioral effects of benzodiazepine ligands in non-dependent, diazepam-dependent and diazepam-withdrawn baboons.
Topics: Animals; Behavior, Animal; Benzodiazepines; Carbolines; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Flumazenil; Ligands; Male; Midazolam; Papio; Receptors, GABA-A; Social Behavior; Substance Withdrawal Syndrome; Substance-Related Disorders | 1991 |
Correlation between gamma-aminobutyric acidA receptor ligand-induced changes in t-butylbicyclophosphoro[35S]thionate binding and 36Cl- uptake in rat cerebrocortical membranes.
Topics: Animals; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Cerebral Cortex; Chloride Channels; Chlorides; Desoxycorticosterone; Diazepam; Ethanol; Flumazenil; gamma-Aminobutyric Acid; In Vitro Techniques; Ligands; Membrane Proteins; Pentobarbital; Pregnanolone; Rats; Receptors, GABA-A; Synaptosomes | 1991 |
Respiratory effects of benzodiazepine-related drugs in awake rhesus monkeys.
Topics: Administration, Inhalation; Alprazolam; Animals; Anti-Anxiety Agents; Appetite Depressants; Benzodiazepines; Buspirone; Carbolines; Carbon Dioxide; Drug Therapy, Combination; Female; Flumazenil; Lorazepam; Macaca mulatta; Male; Pentobarbital; Plethysmography; Pyrazoles; Respiration | 1990 |
Behavioral effects of benzodiazepine antagonists in chlordiazepoxide tolerant and non-tolerant rats.
Topics: Animals; Behavior, Animal; Benzodiazepines; Carbolines; Chlordiazepoxide; Dose-Response Relationship, Drug; Drug Tolerance; Flumazenil; Male; Pyrazoles; Rats; Rats, Inbred F344 | 1989 |
Anxiogenic effects of noreleagnine, a water soluble beta-carboline in rats.
Topics: Animals; Anxiety; Carbolines; Chlordiazepoxide; Conflict, Psychological; Flumazenil; Male; Rats; Rats, Inbred Strains; Reinforcement, Psychology | 1989 |
Opposite effects of diazepam and beta-CCE on immobility and straw-climbing behavior of rats in a modified forced-swim test.
Topics: Animals; Carbolines; Diazepam; Flumazenil; Male; Motor Activity; Rats; Rats, Inbred Strains; Stress, Psychological; Swimming | 1989 |
Blockade of the development of analgesic tolerance to morphine by psychological stress through benzodiazepine receptor mediated mechanism.
Topics: Analgesia; Animals; Carbolines; Diazepam; Drug Tolerance; Flumazenil; Male; Mice; Morphine; Receptors, GABA-A; Stress, Psychological | 1989 |
Behavioral differentiation of benzodiazepine ligands after repeated administration in baboons.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Carbolines; Drug Tolerance; Flumazenil; Injections, Intramuscular; Male; Midazolam; Papio; Substance Withdrawal Syndrome | 1989 |
Effects of benzodiazepines and non-benzodiazepine compounds on the GABA-induced response in frog isolated sensory neurones.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Carbolines; Drug Synergism; Flumazenil; gamma-Aminobutyric Acid; In Vitro Techniques; Neurons, Afferent; Rana catesbeiana | 1989 |
Modulatory actions of benzodiazepine receptor ligands on agonistic behaviour.
Topics: Aggression; Agonistic Behavior; Animals; Behavior, Animal; Carbolines; Chlordiazepoxide; Female; Flumazenil; Maternal Behavior; Mice; Predatory Behavior; Rats; Receptors, GABA-A | 1987 |
Modulation of the electrically evoked release of 5-[3H]hydroxytryptamine from rat cerebral cortex: effects of alpidem, CL 218872, and diazepam.
Topics: Animals; Benzodiazepines; Carbolines; Cerebral Cortex; Diazepam; Electric Stimulation; Flumazenil; gamma-Aminobutyric Acid; Imidazoles; Male; Monoamine Oxidase Inhibitors; Pargyline; Pyrazoles; Pyridazines; Pyridines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin | 1988 |
Behavioral studies with anxiolytic drugs. II. Interactions of zopiclone with ethyl-beta-carboline-3-carboxylate and Ro 15-1788 in squirrel monkeys.
Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Behavior, Animal; Benzodiazepinones; Carbolines; Chlordiazepoxide; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Female; Flumazenil; Food; Male; Piperazines; Punishment; Receptors, GABA-A; Saimiri | 1986 |
Discriminative and aversive stimulus effects of beta-carboline ethyl ester in rhesus monkeys.
Topics: Animals; Avoidance Learning; Benzodiazepines; Benzodiazepinones; Carbolines; Discrimination Learning; Dose-Response Relationship, Drug; Flumazenil; Macaca mulatta; Methohexital; Midazolam | 1986 |
Opposite effects of two ligands for peripheral type benzodiazepine binding sites, PK 11195 and RO5-4864, in a conflict situation in the rat.
Topics: Animals; Benzodiazepinones; Carbolines; Conditioning, Operant; Conflict, Psychological; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Flumazenil; Isoquinolines; Ligands; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
Pharmacological and neurochemical properties of 1,4-diazepines with two annelated heterocycles ('hetrazepines').
Topics: Action Potentials; Aggression; Animals; Anticonvulsants; Azepines; Behavior, Animal; Benzodiazepinones; Brain Chemistry; Carbolines; Cerebral Cortex; Conflict, Psychological; Diazepam; Flumazenil; Heterocyclic Compounds; Humans; Hypnotics and Sedatives; Male; Mice; Motor Activity; Neurons; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sleep; Social Isolation; Wakefulness | 1985 |
Radiation inactivation studies of the benzodiazepine/gamma-aminobutyric acid/chloride ionophore receptor complex.
Topics: Animals; Barbiturates; Benzodiazepines; Benzodiazepinones; Binding Sites; Brain; Carbolines; Cell Membrane; Chlorides; Diazepam; Flumazenil; Flunitrazepam; Ionophores; Male; Molecular Weight; Muscimol; Picrotoxin; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
Blockade of the diazepam-induced increase in rat striatal acetylcholine content by the specific benzodiazepine antagonists ethyl-beta-carboline-3-carboxylate and Ro 15-1788.
Topics: Acetylcholine; Animals; Benzodiazepines; Benzodiazepinones; Brain Chemistry; Carbolines; Corpus Striatum; Diazepam; Female; Flumazenil; Indoles; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
Supraspinal convulsions induced by inverse benzodiazepine agonists in rabbits.
Topics: Animals; Benzodiazepinones; Carbolines; Diazepam; Electroencephalography; Flumazenil; Male; Pyrazoles; Rabbits; Receptors, GABA-A; Seizures | 1985 |
Photoaffinity labelling of benzodiazepine receptors: lack of effect on ligand binding to the nucleoside transport system.
Topics: Affinity Labels; Animals; Benzodiazepinones; Biological Transport, Active; Carbolines; Cerebral Cortex; Dipyridamole; Flumazenil; Flunitrazepam; Guinea Pigs; Nucleosides; Photochemistry; Receptors, GABA-A; Thioinosine | 1985 |
Benzodiazepine-receptor mediated inhibition of isolation-induced aggression in mice.
Topics: Aggression; Animals; Benzodiazepinones; Carbolines; Diazepam; Flumazenil; Humans; Indoles; Male; Mice; Receptors, GABA-A; Social Isolation | 1985 |
Benzodiazepine binding characteristics of embryonic rat brain neurons grown in culture.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Brain; Carbolines; Cells, Cultured; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Flumazenil; gamma-Aminobutyric Acid; Neurons; Pyridazines; Rats; Receptors, GABA-A | 1985 |
Differential sensitivity of "central" and "peripheral" type benzodiazepine receptors to phospholipase A2.
Topics: Animals; Benzodiazepinones; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Cerebral Cortex; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Kidney; Male; Myocardium; Pentobarbital; Phospholipases; Phospholipases A; Phospholipases A2; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1986 |
Discriminative and aversive properties of beta-carboline-3-carboxylic acid ethyl ester, a benzodiazepine receptor inverse agonist, in rhesus monkeys.
Topics: Animals; Avoidance Learning; Benzodiazepines; Benzodiazepinones; Carbolines; Discrimination Learning; Flumazenil; Histamine; Macaca mulatta; Methohexital; Midazolam; Receptors, GABA-A | 1986 |
Differential antagonism of diazepam-induced loss of the righting response.
Topics: Animals; Benzodiazepinones; Carbolines; Columbidae; Diazepam; Flumazenil; Inosine; Male; Pentobarbital; Posture; Receptors, GABA-A; Reflex; Saimiri | 1986 |
Effects of beta-carboline-3-carboxylic acid ethyl ester on suppressed and non-suppressed responding in the rhesus monkey.
Topics: Adrenocorticotropic Hormone; Animals; Blood Pressure; Carbolines; Conditioning, Operant; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Heart Rate; Macaca mulatta; Male; Punishment; Reinforcement Schedule | 1986 |
Diazepam potentiates GABA-contraction in guinea-pig ileum.
Topics: Animals; Baclofen; Benzodiazepinones; Carbolines; Diazepam; Drug Synergism; Electric Stimulation; Flumazenil; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth | 1986 |
Isoniazid-induced convulsions in rats: effects of Ro 15-1788 and beta-CCE.
Topics: Animals; Benzodiazepinones; Carbolines; Dose-Response Relationship, Drug; Drug Interactions; Flumazenil; Indoles; Isoniazid; Male; Rats; Rats, Inbred Strains; Seizures | 1985 |
Chlordiazepoxide enhances the anxiogenic action of CGS 8216 in the social interaction test: evidence for benzodiazepine withdrawal?
Topics: Animals; Anxiety; Benzodiazepinones; Carbolines; Chlordiazepoxide; Flumazenil; Humans; Male; Pyrazoles; Rats; Social Behavior; Species Specificity; Substance Withdrawal Syndrome | 1985 |
Anticonvulsant actions of fominoben: possible involvement of benzodiazepine receptors.
Topics: 3-Mercaptopropionic Acid; Aminophylline; Animals; Anticonvulsants; Benzodiazepinones; Binding, Competitive; Brain Chemistry; Carbolines; Flumazenil; Male; Mice; Morpholines; Pentylenetetrazole; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Seizures; Synaptosomes | 1984 |
An imidazodiazepine derivative, Ro 15-1788, behaves as a weak partial agonist in the crossed extensor reflex.
Topics: Animals; Benzodiazepinones; Carbolines; Chlorpromazine; Diazepam; Flumazenil; Male; Phenobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Reflex | 1984 |
The effects of benzodiazepine agonists, inverse agonists and Ro 15-1788 on the responses of the superior cervical ganglion to GABA in vitro.
Topics: Animals; Barbiturates; Benzodiazepinones; Bicuculline; Carbolines; Chlordiazepoxide; Flumazenil; Flurazepam; gamma-Aminobutyric Acid; Ganglia, Sympathetic; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1984 |
The benzodiazepine receptor and sleep.
Topics: Animals; Barbiturates; Benzodiazepines; Benzodiazepinones; Calcium; Carbolines; Diazepam; Flumazenil; Flurazepam; Humans; Motor Activity; Nifedipine; Phenobarbital; Pyrazoles; Rats; Receptors, GABA-A; Sleep; Synaptosomes | 1984 |
An in vitro binding assay which differentiates benzodiazepine 'agonists' and 'antagonists'.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Binding, Competitive; Carbolines; Flumazenil; gamma-Aminobutyric Acid; Indoles; Male; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, GABA-A | 1982 |
A three-state model of the benzodiazepine receptor explains the interactions between the benzodiazepine antagonist Ro 15-1788, benzodiazepine tranquilizers, beta-carbolines, and phenobarbitone.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Carbolines; Cats; Female; Flumazenil; Hippocampus; In Vitro Techniques; Indoles; Male; Mice; Models, Biological; Phenobarbital; Rats; Receptors, Cell Surface; Receptors, GABA-A; Spinal Cord | 1982 |
Pharmacological and behavioural studies of benzodiazepine antagonists and contragonists.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Benzodiazepinones; Carbolines; Conditioning, Operant; Conflict, Psychological; Flumazenil; Ganglia, Spinal; Hippocampus; Male; Rats; Seizures; Social Behavior | 1983 |
Antagonists of benzodiazepines: functional aspects.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Carbolines; Chlorides; Flumazenil; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Ion Channels; Narcotic Antagonists; Parasympathomimetics; Pyrazoles; Receptors, Cell Surface; Receptors, GABA-A; Substance-Related Disorders; Xanthines | 1983 |
Unusual interactions of benzodiazepine receptor antagonists.
Topics: Animals; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Biological Assay; Carbolines; Flumazenil; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Indoles; Rats; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter; Seizures | 1982 |
Intrinsic actions of benzodiazepine antagonists.
Topics: Animals; Benzodiazepinones; Brain; Carbolines; Chlordiazepoxide; Dose-Response Relationship, Drug; Exploratory Behavior; Flumazenil; Indoles; Male; Motor Activity; Muridae; Receptors, Drug; Receptors, GABA-A | 1982 |
Benzodiazepine receptor-mediated experimental "anxiety" in primates.
Topics: Animals; Anxiety; Benzodiazepinones; Blood Pressure; Carbolines; Disease Models, Animal; Epinephrine; Flumazenil; Heart Rate; Humans; Hydrocortisone; Macaca mulatta; Male; Norepinephrine; Receptors, Drug; Receptors, GABA-A | 1982 |
Antagonism of the anticonflict effects of chlordiazepoxide by beta-carboline carboxylic acid ethyl ester, Ro 15-1788 and ACTH(4--10).
Topics: Adrenocorticotropic Hormone; Animals; Arousal; Benzodiazepinones; Carbolines; Chlordiazepoxide; Conditioning, Operant; Conflict, Psychological; Fear; Flumazenil; Indoles; Male; Muridae; Peptide Fragments; Receptors, Cell Surface; Receptors, GABA-A; Reinforcement Schedule | 1982 |
Chronic RO 15-1788 treatment increases the number of benzodiazepine receptors in rat cerebral cortex and hippocampus.
Topics: Animals; Benzodiazepinones; Carbolines; Cerebral Cortex; Female; Flumazenil; Flunitrazepam; Hippocampus; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Contrasting effects of ethyl beta-carboline-3-carboxylate (beta CCE) and diazepam on cerebellar cyclic GMP content and antagonism of both effects by Ro 15-1788, a specific benzodiazepine receptor blocker.
Topics: Animals; Benzodiazepinones; Carbolines; Cerebellum; Cyclic GMP; Diazepam; Flumazenil; In Vitro Techniques; Indoles; Isoniazid; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Interactions of ethyl-beta-carboline-3-carboxylate and Ro 15-1788 with CGS 8216 in an animal model of anxiety.
Topics: Animals; Anxiety; Benzodiazepinones; Carbolines; Disease Models, Animal; Drug Interactions; Flumazenil; Humans; Indoles; Male; Pyrazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A; Social Behavior | 1983 |
New concepts in the neurobiology of anxiety.
Topics: Animals; Anxiety; Barbiturates; Behavior; Behavior, Animal; Benzodiazepines; Benzodiazepinones; Carbolines; Central Nervous System; Flumazenil; Humans; Macaca mulatta; Pyrazoles; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Benzodiazepines receptor binding in vivo: pharmacokinetic and pharmacological significance.
Topics: Adrenal Glands; Animals; Benzodiazepinones; Brain; Carbolines; Corticosterone; Diazepam; Flumazenil; Flunitrazepam; Kinetics; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Interactions of different ligand classes with the benzodiazepine receptor.
Topics: Affinity Labels; Animals; Benzodiazepinones; Binding, Competitive; Carbolines; Flumazenil; gamma-Aminobutyric Acid; Humans; Ligands; Membranes; Rats; Receptors, Cell Surface; Receptors, GABA-A; Sodium Chloride | 1983 |
Ligands for benzodiazepine receptors with positive and negative efficacy.
Topics: Animals; Benzodiazepinones; Carbolines; Flumazenil; Humans; Ligands; Radioligand Assay; Receptors, Cell Surface; Receptors, GABA-A | 1984 |
Ro 15-1788 and beta-CCE selectively eliminate diazepam-induced feeding in the rabbit.
Topics: Animals; Benzodiazepinones; Carbolines; Chlorpromazine; Cyproheptadine; Diazepam; Eating; Flumazenil; Indoles; Rabbits; Receptors, Cell Surface; Receptors, GABA-A; Water Deprivation | 1984 |
Inhibition of adenosine uptake into rat brain synaptosomes by prostaglandins, benzodiazepines and other centrally active compounds.
Topics: Adenosine; Animals; Benzodiazepines; Benzodiazepinones; Brain; Calmodulin; Carbolines; Flumazenil; Hydroxyzine; Imidazoles; Male; Prostaglandins; Pyrazoles; Rats; Rats, Inbred Strains; Sulfonamides; Synaptosomes | 1983 |
Studies on [3H]diazepam and [3H]ethyl-beta-carboline carboxylate binding to rat brain in vivo. I. Regional variations in displacement.
Topics: Animals; Benzodiazepinones; Brain; Carbolines; Convulsants; Diazepam; Flumazenil; Flurazepam; Indoles; Male; Rats; Rats, Inbred Strains; Tissue Distribution | 1983 |
RO5-4864 inhibits the binding of [35S]t-butylbicyclophosphorothionate to rat brain membranes.
Topics: Androstanes; Animals; Azasteroids; Benzodiazepinones; Bicuculline; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Carbolines; Cell Membrane; Cerebellum; Cerebral Cortex; Dose-Response Relationship, Drug; Flumazenil; Hippocampus; Male; Picrotoxin; Radioligand Assay; Rats | 1984 |
The anxiogenic action of benzodiazepine antagonists.
Topics: Animals; Anxiety; Benzodiazepines; Benzodiazepinones; Carbolines; Flumazenil; Humans; Indoles; Interpersonal Relations; Ligands; Male; Rats | 1982 |
Opposite effects of midazolam and beta-carboline-3-carboxylate ethyl ester on the release of dopamine from rat nucleus accumbens measured by in vivo microdialysis.
Topics: Adenosine; Animals; Carbolines; Dopamine; Dose-Response Relationship, Drug; Flumazenil; Ligands; Male; Microdialysis; Midazolam; Nucleus Accumbens; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Tetrodotoxin; Theobromine; Xanthines | 1994 |
Combination of buspirone and other drugs with beta-CCE in monkeys: effects on respiration and behavior.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Buspirone; Carbolines; Carbon Dioxide; Conditioning, Operant; Drug Interactions; Female; Flumazenil; Lorazepam; Macaca mulatta; Male; Pyridazines; Respiration; Respiratory Mechanics; Tidal Volume | 1993 |
Benzodiazepine inverse agonists augment long-term potentiation in CA1 and CA3 of guinea pig hippocampal slices.
Topics: Animals; Benzodiazepines; Carbolines; Electric Stimulation; Evoked Potentials; Flumazenil; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Neuronal Plasticity; Psychotropic Drugs; Pyrazoles; Quinolones | 1993 |
Down-regulation of benzodiazepine receptors by ethyl beta-carboline-3-carboxylate in cerebrocortical neurons.
Topics: Animals; Carbolines; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Down-Regulation; Flumazenil; Flunitrazepam; Mice; Receptors, GABA-A | 1996 |
Effects of negative allosteric modulators of gamma-aminobutyric acidA receptors on complex behavioral processes in monkeys.
Topics: Allosteric Regulation; Alprazolam; Animals; Carbolines; Conditioning, Psychological; Discrimination Learning; Dose-Response Relationship, Drug; Erythrocebus patas; Female; Flumazenil; Receptors, GABA-A | 1997 |
Discrepancy of benzodiazepine receptor occupancy between 3H-flumazenil and 125I-iomazenil in intact mouse brain.
Topics: Animals; Binding, Competitive; Brain; Carbolines; Flumazenil; Flunitrazepam; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Male; Mice; Nitrazepam; Receptors, GABA-A; Triazolam; Tritium | 1999 |
Discriminative stimulus effects of ethyl-beta-carboline-3-carboxylate at two training doses in rats.
Topics: Animals; Carbolines; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Male; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1999 |
Discriminative stimulus effects of flumazenil in untreated and in diazepam-treated rhesus monkeys.
Topics: Animals; Azides; Benzodiazepines; Carbolines; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Modulators; Macaca mulatta; Male; Receptors, GABA-A | 1999 |
Antagonism of the discriminative stimulus effects of positive gamma-aminobutyric acid(A) modulators in rhesus monkeys discriminating midazolam.
Topics: Animals; Azides; Benzodiazepines; Carbolines; Diazepam; Discrimination Learning; Drug Antagonism; Female; Flumazenil; GABA Modulators; Macaca mulatta; Male; Midazolam; Receptors, GABA-A | 2000 |
Benzodiazepines induce a conformational change in the region of the gamma-aminobutyric acid type A receptor alpha(1)-subunit M3 membrane-spanning segment.
Topics: 4-Chloromercuribenzenesulfonate; Amino Acid Substitution; Animals; Benzodiazepines; Carbolines; Cysteine; Diazepam; Flumazenil; GABA Modulators; Membrane Proteins; Oocytes; Protein Conformation; Rats; Receptors, GABA-A; Xenopus laevis | 2000 |
Remarkable selectivity of the in vivo binding of [3H]Ro15-4513 to α5 subtype of benzodiazepine receptor in the living mouse brain.
Topics: Affinity Labels; Animals; Azides; Benzodiazepines; Binding, Competitive; Brain; Carbolines; Dose-Response Relationship, Drug; Flumazenil; Flunitrazepam; Male; Mice; Protein Subunits; Receptors, GABA-A; Tritium | 2010 |