flumazenil and baclofen

flumazenil has been researched along with baclofen in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19905 (14.71)18.7374
1990's17 (50.00)18.2507
2000's8 (23.53)29.6817
2010's3 (8.82)24.3611
2020's1 (2.94)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Inano, S1
Coop, CF; McNaughton, N; Scott, DJ1
Demazière, J; Gaye, M; Marcoux, L; Ndiaye, M; Saissy, JM; Seck, M; Vitris, M1
File, SE; Hitchcott, PK; Zharkovsky, A1
Demazière, J; Gaye, M; Marcoux, L; Saissy, JM; Seck, M; Vitris, M1
Cremades, A; Del Rio-Garcia, J1
Greentree, SG; Pertwee, RG; Swift, PA1
Karobath, M; Supavilai, P1
Ciuffi, M; Franchi-Micheli, S; Luzzi, S; Rosi, E; Spagnesi, S; Zilletti, L1
Allikmets, LH; Rägo, LK1
Kaneto, H; Rahman, AF; Takahashi, M1
Lorini, FL; Sicignano, A1
Emerich, DF; Stackman, RW; Taylor, LA; Walsh, TJ1
Ishima, T; Iwasaki, T; Kimura, K; Nakagawa, Y1
Byrnes, SM; Hardy, PA; Watson, GW1
Berardelli, A; Inghilleri, M; Manfredi, M; Marchetti, P1
Chern, TL; Kwan, A1
Dressnandt, J; Klingelhöfer, J; Konstanzer, A; Pfab, R; Weinzierl, FX1
Celis, ME; Cremer, MC; De Barioglio, SR1
Katukov, VIu; Lesnichuk, SA; Porodenko, NV; Severin, ES1
Bowery, N; Castro, AR; Castro-Lopes, JM1
Abraini, JH; Balon, N; Kriem, B; Risso, JJ; Rostain, JC1
Choi, KB; Jeong, JH; Moon, NJ; Park, ES; Sohn, UD1
Carter, LP; Coop, A; France, CP; Koek, W; Wu, H1
de Tourtchaninoff, M; Goffin, E; Hantson, P; Laterre, PF; Lois, F; Vanbinst, R; Wallemacq, P1
Breese, GR; Knapp, DJ; Overstreet, DH1
McGregor, IS; van Nieuwenhuijzen, PS1
Chen, SY; Chu, FY; Tarng, DC; Yang, CY1

Reviews

2 review(s) available for flumazenil and baclofen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Intrathecal baclofen in tetanus: four cases and a review of reported cases.
    Intensive care medicine, 1997, Volume: 23, Issue:8

    Topics: Adult; Aged; Antidotes; Baclofen; Female; Flumazenil; GABA Agonists; Humans; Injections, Spinal; Male; Middle Aged; Spasm; Tetanus

1997

Other Studies

32 other study(ies) available for flumazenil and baclofen

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
[Effects of agonists and antagonists of benzodiazepine, GABA and NMDA receptors, on caffeine-induced seizures in mice].
    Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology, 1992, Volume: 12, Issue:4

    Topics: Animals; Baclofen; Benzodiazepines; Caffeine; Diazepam; Dizocilpine Maleate; Flumazenil; Male; Mice; Muscimol; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic; Seizures

1992
Pindolol antagonizes the effects on hippocampal rhythmical slow activity of clonidine, baclofen and 8-OH-DPAT, but not chlordiazepoxide and sodium amylobarbitone.
    Neuroscience, 1992, Volume: 46, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Amobarbital; Animals; Baclofen; Chlordiazepoxide; Clonidine; Electric Stimulation; Electrodes; Electroencephalography; Flumazenil; Hippocampus; Male; Pindolol; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes

1992
Treatment of severe tetanus by intrathecal injections of baclofen without artificial ventilation.
    Intensive care medicine, 1992, Volume: 18, Issue:4

    Topics: Adolescent; Adult; Africa; Age Factors; Aged; Baclofen; Blood Gas Analysis; Coma; Creatine Kinase; Developing Countries; Female; Flumazenil; Humans; Injections, Spinal; Male; Middle Aged; Prospective Studies; Respiration, Artificial; Respiratory Insufficiency; Tetanus

1992
Effects of nitrendipine, chlordiazepoxide, flumazenil and baclofen on the increased anxiety resulting from alcohol withdrawal.
    Progress in neuro-psychopharmacology & biological psychiatry, 1992, Volume: 16, Issue:1

    Topics: Animals; Anxiety; Baclofen; Chlordiazepoxide; Diazepam; Ethanol; Flumazenil; Interpersonal Relations; Male; Nitrendipine; Rats; Substance Withdrawal Syndrome; Tremor

1992
Flumazenil counteracts intrathecal baclofen-induced central nervous system depression in tetanus.
    Anesthesiology, 1992, Volume: 76, Issue:6

    Topics: Adult; Baclofen; Central Nervous System; Depression, Chemical; Female; Flumazenil; Humans; Injections, Spinal; Male; Middle Aged; Tetanus

1992
GABAergic mechanisms in morphine-induced hypothermia.
    European journal of pharmacology, 1990, Oct-23, Volume: 187, Issue:3

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Baclofen; Body Temperature; Female; Flumazenil; gamma-Aminobutyric Acid; Male; Morphine; Rats; Rats, Inbred Strains

1990
Drugs which stimulate or facilitate central GABAergic transmission interact synergistically with delta-9-tetrahydrocannabinol to produce marked catalepsy in mice.
    Neuropharmacology, 1988, Volume: 27, Issue:12

    Topics: Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Catalepsy; Dronabinol; Drug Synergism; Flumazenil; Flupenthixol; Flurazepam; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Nipecotic Acids; Receptors, GABA-A; Strychnine; Taurine; Tiagabine

1988
Modulation of acetylcholine release from rat striatal slices by the GABA/benzodiazepine receptor complex.
    Life sciences, 1985, Feb-04, Volume: 36, Issue:5

    Topics: Acetylcholine; Animals; Atropine; Baclofen; Benzodiazepinones; Clonazepam; Corpus Striatum; Electric Stimulation; Flumazenil; gamma-Aminobutyric Acid; Haloperidol; In Vitro Techniques; Isoxazoles; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A

1985
Diazepam potentiates GABA-contraction in guinea-pig ileum.
    Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 279, Issue:1

    Topics: Animals; Baclofen; Benzodiazepinones; Carbolines; Diazepam; Drug Synergism; Electric Stimulation; Flumazenil; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth

1986
The action of benzodiazepine antagonist Ro 15-1788 on the effects of GABA-ergic drugs.
    Naunyn-Schmiedeberg's archives of pharmacology, 1983, Volume: 324, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aggression; Animals; Baclofen; Benzodiazepines; Benzodiazepinones; Brain Chemistry; Flumazenil; gamma-Aminobutyric Acid; Humans; Male; Motor Activity; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A

1983
Role of GABAergic systems in the development of morphine tolerance in formalin-treated mice.
    Japanese journal of pharmacology, 1995, Volume: 68, Issue:2

    Topics: Analgesics, Opioid; Animals; Baclofen; Bicuculline; Diazepam; Drug Tolerance; Flumazenil; Formaldehyde; GABA Agonists; GABA Antagonists; Male; Mice; Mice, Inbred Strains; Morphine; Muscimol; Pain; Pain Measurement; Receptors, GABA

1995
Does flumazenil antagonize baclofen?
    Intensive care medicine, 1994, Volume: 20, Issue:7

    Topics: Baclofen; Flumazenil; Humans; Tetanus

1994
Intraseptal injection of GABA and benzodiazepine receptor ligands alters high-affinity choline transport in the hippocampus.
    Brain research bulletin, 1993, Volume: 31, Issue:3-4

    Topics: Acetylcholinesterase; Animals; Baclofen; Brain; Carbolines; Chlordiazepoxide; Choline; Convulsants; Flumazenil; gamma-Aminobutyric Acid; Hippocampus; Injections; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptosomes

1993
Interaction between benzodiazepine and GABA-A receptors in state-dependent learning.
    Life sciences, 1993, Volume: 52, Issue:24

    Topics: Animals; Avoidance Learning; Baclofen; Bicuculline; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Male; Muscimol; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Reference Values

1993
Flumazenil: an unreliable antagonist in baclofen overdose.
    Anaesthesia, 1996, Volume: 51, Issue:5

    Topics: Adult; Antidotes; Baclofen; Coma; Female; Flumazenil; GABA Modulators; Humans; Muscle Relaxants, Central

1996
Effects of diazepam, baclofen and thiopental on the silent period evoked by transcranial magnetic stimulation in humans.
    Experimental brain research, 1996, Volume: 109, Issue:3

    Topics: Adult; Baclofen; Diazepam; Electric Stimulation; Evoked Potentials; Flumazenil; GABA Agonists; GABA Modulators; Humans; Middle Aged; Motor Cortex; Neural Inhibition; Thiopental; Transcranial Magnetic Stimulation

1996
Flumazenil-induced seizure accompanying benzodiazepine and baclofen intoxication.
    The American journal of emergency medicine, 1996, Volume: 14, Issue:2

    Topics: Adult; Antidotes; Baclofen; Benzodiazepines; Drug Interactions; Drug Overdose; Female; Flumazenil; Humans; Muscle Relaxants, Central; Seizures; Suicide, Attempted

1996
Interaction between alpha-MSH and gabaergic agents upon striatal cAMP levels: an in vitro model.
    Peptides, 1998, Volume: 19, Issue:2

    Topics: alpha-MSH; Animals; Baclofen; Benzazepines; Corpus Striatum; Cyclic AMP; Diazepam; Drug Interactions; Flumazenil; GABA Agents; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; In Vitro Techniques; Male; Models, Neurological; Rats; Rats, Wistar; Receptors, Dopamine D1

1998
[Characteristics of human lymphocyte benzodiazepine receptors].
    Biulleten' eksperimental'noi biologii i meditsiny, 1998, Volume: 126, Issue:10

    Topics: Adult; Baclofen; Benzodiazepinones; Binding, Competitive; Diazepam; Flumazenil; GABA Agonists; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Ligands; Lymphocytes; Male; Receptors, GABA-A

1998
Baclofen and midazolam alter c-fos induction by peripheral noxious or innocuous stimulation in the spinal cord of normal and monoarthritic rats.
    Neuropharmacology, 1999, Volume: 38, Issue:11

    Topics: Animals; Arthritis, Experimental; Baclofen; Flumazenil; GABA Agonists; GABA Antagonists; GABA Modulators; Genes, fos; Male; Midazolam; Organophosphorus Compounds; Physical Stimulation; Rats; Rats, Wistar; Spinal Cord; Stimulation, Chemical

1999
Gamma-aminobutyric acid neuropharmacological investigations on narcosis produced by nitrogen, argon, or nitrous oxide.
    Anesthesia and analgesia, 2003, Volume: 96, Issue:3

    Topics: Anesthesia, Inhalation; Animals; Argon; Baclofen; Flumazenil; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Motor Activity; Nitrogen; Nitrous Oxide; Pyridazines; Rats; Rats, Sprague-Dawley

2003
Benzodiazepine system is involved in hyperalgesia in rats induced by the exposure to extremely low frequency magnetic fields.
    Archives of pharmacal research, 2005, Volume: 28, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Baclofen; Bicuculline; Diazepam; Electromagnetic Fields; Flumazenil; GABA Antagonists; GABA Modulators; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Hot Temperature; Hyperalgesia; Injections, Intraventricular; Male; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, GABA-A

2005
Discriminative stimulus effects of flumazenil: perceptual masking by baclofen, and lack of substitution with gamma-hydroxybutyrate and its precursors 1,4-butanediol and gamma-butyrolactone.
    Behavioural pharmacology, 2006, Volume: 17, Issue:3

    Topics: 4-Butyrolactone; Animals; Baclofen; Benzocycloheptenes; Butylene Glycols; Columbidae; Discrimination, Psychological; Dose-Response Relationship, Drug; Flumazenil; GABA Agonists; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Organophosphorus Compounds; Sodium Oxybate

2006
Prolonged unconsciousness in a patient on automated peritoneal dialysis.
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2006, Volume: 13, Issue:6

    Topics: Aged; Antidotes; Automation; Baclofen; Chromatography, High Pressure Liquid; Critical Care; Electroencephalography; Emergency Treatment; Flumazenil; Fluorescence Polarization Immunoassay; GABA Agonists; Humans; Kidney Failure, Chronic; Male; Medication Errors; Metabolic Clearance Rate; Muscle Relaxants, Central; Peritoneal Dialysis; Respiration, Artificial; Self Administration; Substance Abuse Detection; Unconsciousness

2006
Baclofen blocks expression and sensitization of anxiety-like behavior in an animal model of repeated stress and ethanol withdrawal.
    Alcoholism, clinical and experimental research, 2007, Volume: 31, Issue:4

    Topics: Alcohol Drinking; Animals; Anxiety; Baclofen; Body Weight; Central Nervous System Depressants; Diet; Ethanol; Flumazenil; GABA Agonists; GABA Modulators; Interpersonal Relations; Male; Rats; Rats, Sprague-Dawley; Restraint, Physical; Stress, Psychological; Substance Withdrawal Syndrome

2007
Sedative and hypothermic effects of gamma-hydroxybutyrate (GHB) in rats alone and in combination with other drugs: assessment using biotelemetry.
    Drug and alcohol dependence, 2009, Aug-01, Volume: 103, Issue:3

    Topics: Animals; Baclofen; Benzazepines; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Flumazenil; Hypothermia; Illicit Drugs; Male; Methamphetamine; Morpholines; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Naltrexone; Rats; Rats, Wistar; Ritanserin; Sodium Oxybate; Telemetry

2009
Flumazenil partially reverses gamma-hydroxybutyrate (GHB)-induced coma: a case report.
    The American journal of drug and alcohol abuse, 2022, 09-03, Volume: 48, Issue:5

    Topics: Baclofen; Coma; Flumazenil; Humans; Sodium Oxybate

2022