flufenamic acid and diclofenac

flufenamic acid has been researched along with diclofenac in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19904 (11.76)18.7374
1990's3 (8.82)18.2507
2000's9 (26.47)29.6817
2010's15 (44.12)24.3611
2020's3 (8.82)2.80

Authors

AuthorsStudies
Chalmers, DK; Craik, DJ; Iskander, MN; Kolliniatis, E; Munro, SL; Scholz, GH; Stockigt, JR; Topliss, DJ1
Chang, TK; Ensom, MH; Kiang, TK1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Arsequell, G; Blasi, D; Bosch, L; Centeno, NB; Cotrina, EY; Pinto, M; Planas, A; Quintana, J; Valencia, G; Vilà, M1
Bellman, K; Knegtel, RM; Settimo, L1
Headey, SJ; Hughes, ML; Laguerre, A; Mohanty, B; Patil, R; Porter, CJ; Scanlon, MJ; Wielens, J; Williams, ML1
Maccari, R; Ottanà, R1
Kourounakis, PN; Kourti, M; Rekka, EA; Theodosis-Nobelos, P; Tziona, P1
Bennis, K; Ducki, S; Lesage, F; Vivier, D1
Gavalas, A; Kourti, M; Rekka, EA; Theodosis-Nobelos, P1
Boa, AN; Chandrabalan, A; McPhillie, MJ; Morice, AH; Sadofsky, LR1
Mizuguchi, M; Yokoyama, T1
Kawai, K; Kuzuna, S; Morimoto, S1
Pradalier, A; Vincent, D1
Stratz, T1
Cherevatov, BG; Cherevatova, SKh; Shelest, AN; Volnenko, NB1
Machtey, I1
Sigidin, IaA; Tsvetkova, ES1
Abdel-Hamid, ME; Hamza, H; Novotny, L1
Bevin, TH; Fuller, JR; Herbison, P; Molteno, AC; Vote, BJ1
Gao, F; Hirata, K; Horie, T; Sosogi, A; Tomimatsu, T2
Chen, YL; Chu, CY; Lin, LJ; Sun, CC1
Almeida, MR; Alves, I; Arsequell, G; Cardoso, I; Macedo, B; Planas, A; Saraiva, MJ; Valencia, G1
Iley, J; Järvinen, T; Mendes, E; Moreira, R; Mota-Filipe, H; Rautio, J; Ribeiro, L; Silva, N1
Atherton, J; Bauman, J; Kohl, C; Lam, W; Lou, Z; Mutlib, A; Reily, M; Walker, GS1
Domańska, U; Pelczarska, A; Pobudkowska, A1
Carvalho, G; Marques, R; Noronha, JP; Oehmen, A; Reis, MA; Salgado, R1
Arce-Franco, M; Armas-González, E; Cadenas, S; Díaz-González, F; Domínguez-Luis, M; Feria, M; Herrera-García, A; Lorenzo-Díaz, F; Rodríguez-Pardo, M; Sánchez-Madrid, F1
Kumar, KH; Lokanatha, V; Madhava, G; Raju, CN; Ramana, KV; Rani, AU; Rao, DS; Sudhana, SM1
Boncheva Bettex, M; Kopečná, M; Kováčik, A; Novák, P; Vávrová, K1
Ikushiro, S; Iwai, Y; Nishikawa, M; Sakaki, T; Sugimoto, H; Takita, T; Yasuda, K; Yasukawa, K; Yogo, Y1

Reviews

5 review(s) available for flufenamic acid and diclofenac

ArticleYear
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
    Journal of medicinal chemistry, 2016, 06-09, Volume: 59, Issue:11

    Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Structure; Neuroprotective Agents; Pain; Potassium Channels, Tandem Pore Domain; Structure-Activity Relationship

2016
Transthyretin Amyloidogenesis Inhibitors: From Discovery to Current Developments.
    Journal of medicinal chemistry, 2020, 12-10, Volume: 63, Issue:23

    Topics: Amyloid; Crystallography, X-Ray; Drug Discovery; Humans; Molecular Structure; Prealbumin

2020
[Migraine and non-steroidal anti-inflammatory agents].
    Pathologie-biologie, 1992, Volume: 40, Issue:4

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Ergotamine; Flufenamic Acid; Flurbiprofen; Humans; Metoclopramide; Migraine Disorders; Naproxen; ortho-Aminobenzoates; Randomized Controlled Trials as Topic

1992
Allergic contact dermatitis from etofenamate without cross-sensitization to other anthranilic acid derivatives.
    Dermatology (Basel, Switzerland), 2003, Volume: 206, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross Reactions; Dermatitis, Allergic Contact; Diclofenac; Flufenamic Acid; Humans; Ketoprofen; Male; Patch Tests; Thigh

2003

Trials

3 trial(s) available for flufenamic acid and diclofenac

ArticleYear
[Migraine and non-steroidal anti-inflammatory agents].
    Pathologie-biologie, 1992, Volume: 40, Issue:4

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Ergotamine; Flufenamic Acid; Flurbiprofen; Humans; Metoclopramide; Migraine Disorders; Naproxen; ortho-Aminobenzoates; Randomized Controlled Trials as Topic

1992
[Intramuscular etofenamate in the treatment of acute lumbago. Effectiveness and tolerance in comparison with intramuscular diclofenac-Na].
    Fortschritte der Medizin, 1990, Apr-30, Volume: 108, Issue:13

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Diclofenac; Female; Flufenamic Acid; Humans; Injections, Intramuscular; Male; Middle Aged; Randomized Controlled Trials as Topic; Single-Blind Method

1990
[Comparative effectiveness of new antirheumatic drugs].
    Terapevticheskii arkhiv, 1980, Volume: 52, Issue:11

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; Flufenamic Acid; Humans; Indomethacin; Naproxen

1980

Other Studies

27 other study(ies) available for flufenamic acid and diclofenac

ArticleYear
Thyroid hormone uptake by hepatocytes: structure-activity relationships of phenylanthranilic acids with inhibitory activity.
    Journal of medicinal chemistry, 1993, Apr-30, Volume: 36, Issue:9

    Topics: Animals; Chemical Phenomena; Chemistry, Physical; Flufenamic Acid; Liver; Liver Neoplasms, Experimental; Meclofenamic Acid; Mefenamic Acid; Molecular Structure; ortho-Aminobenzoates; Rats; Structure-Activity Relationship; Triiodothyronine; Tumor Cells, Cultured

1993
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Modulation of the fibrillogenesis inhibition properties of two transthyretin ligands by halogenation.
    Journal of medicinal chemistry, 2013, Nov-27, Volume: 56, Issue:22

    Topics: Diflunisal; Flufenamic Acid; Halogenation; Humans; Kinetics; Ligands; Models, Molecular; Prealbumin; Protein Multimerization; Protein Structure, Secondary; Structure-Activity Relationship

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Characterization of two distinct modes of drug binding to human intestinal fatty acid binding protein.
    ACS chemical biology, 2014, Nov-21, Volume: 9, Issue:11

    Topics: Fatty Acid-Binding Proteins; Fluorescent Dyes; Humans; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Spectrometry, Fluorescence

2014
Targeting aldose reductase for the treatment of diabetes complications and inflammatory diseases: new insights and future directions.
    Journal of medicinal chemistry, 2015, Mar-12, Volume: 58, Issue:5

    Topics: Aldehyde Reductase; Aldo-Keto Reductases; Diabetes Complications; Diabetes Mellitus; Enzyme Inhibitors; Humans; Inflammation

2015
Esters of some non-steroidal anti-inflammatory drugs with cinnamyl alcohol are potent lipoxygenase inhibitors with enhanced anti-inflammatory activity.
    Bioorganic & medicinal chemistry letters, 2015, Nov-15, Volume: 25, Issue:22

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cinnamates; Edema; Esters; Glycine max; Hyperlipidemias; Indoleacetic Acids; Lipoxygenase Inhibitors; Polyethylene Glycols; Propanols; Propionates; Rats; Thioctic Acid

2015
Amides of non-steroidal anti-inflammatory drugs with thiomorpholine can yield hypolipidemic agents with improved anti-inflammatory activity.
    Bioorganic & medicinal chemistry letters, 2016, Feb-01, Volume: 26, Issue:3

    Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cholesterol; Cholesterol, LDL; Edema; Hyperlipidemias; Hypolipidemic Agents; Morpholines; Rats; Triglycerides

2016
N-Cinnamoylanthranilates as human TRPA1 modulators: Structure-activity relationships and channel binding sites.
    European journal of medicinal chemistry, 2019, May-15, Volume: 170

    Topics: Animals; Calcium Signaling; Cinnamates; Guinea Pigs; HEK293 Cells; Humans; Male; Molecular Docking Simulation; ortho-Aminobenzoates; Structure-Activity Relationship; TRPA1 Cation Channel

2019
Effects of some anti-rheumatic agents on copper-catalyzed thermal aggregation of gamma globulin.
    Agents and actions, 1979, Volume: 9, Issue:4

    Topics: Anti-Inflammatory Agents; Aspirin; Copper; Dexamethasone; Diclofenac; Flufenamic Acid; gamma-Globulins; Gold Sodium Thiomalate; Hot Temperature; Humans; Ibuprofen; Indans; Indomethacin; Penicillamine; Phenylbutazone; Prednisolone

1979
[Topical use of Rheumon-Gel in the combined treatment of patients with rheumatoid arthritis].
    Terapevticheskii arkhiv, 1987, Volume: 59, Issue:12

    Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Diclofenac; Drug Evaluation; Drug Therapy, Combination; Female; Flufenamic Acid; Humans; Male; Middle Aged; Prednisolone

1987
Diclofenac in the treatment of painful joints and traumatic tendinitis (including strains and sprains): a brief review.
    Seminars in arthritis and rheumatism, 1985, Volume: 15, Issue:2 Suppl 1

    Topics: Diclofenac; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Joint Diseases; Ketoprofen; Naproxen; Pain; Sprains and Strains; Tendinopathy

1985
Determination of diclofenac sodium, flufenamic acid, indomethacin and ketoprofen by LC-APCI-MS.
    Journal of pharmaceutical and biomedical analysis, 2001, Volume: 24, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Capsules; Chromatography, High Pressure Liquid; Diclofenac; Flufenamic Acid; Indomethacin; Ketoprofen; Mass Spectrometry; Sensitivity and Specificity; Tablets

2001
Anti-inflammatory fibrosis suppression in threatened trabeculectomy bleb failure produces good long term control of intraocular pressure without risk of sight threatening complications.
    The British journal of ophthalmology, 2002, Volume: 86, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Colchicine; Diclofenac; Drug Therapy, Combination; Female; Fibrosis; Flufenamic Acid; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Piroxicam; Prednisone; Prospective Studies; Trabecular Meshwork; Trabeculectomy; Treatment Outcome; Vision Disorders

2002
Effects of non-steroidal anti-inflammatory drugs on the methotrexate transport in rat small intestine.
    Scandinavian journal of gastroenterology, 2003, Volume: 38, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport, Active; Diclofenac; Flufenamic Acid; Folic Acid Antagonists; Indomethacin; Intestine, Small; Male; Methotrexate; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase

2003
Non-steroidal anti-inflammatory drugs affect the methotrexate transport in IEC-6 cells.
    Life sciences, 2003, Jun-13, Volume: 73, Issue:4

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cell Line; Coloring Agents; Diclofenac; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flufenamic Acid; Hydrogen-Ion Concentration; Indomethacin; Intestine, Small; Intestines; Methotrexate; Phosphorylation; Rats; Tetrazolium Salts; Thiazoles; Time Factors

2003
Selective binding to transthyretin and tetramer stabilization in serum from patients with familial amyloidotic polyneuropathy by an iodinated diflunisal derivative.
    The Biochemical journal, 2004, Jul-15, Volume: 381, Issue:Pt 2

    Topics: Amyloid Neuropathies; Diclofenac; Diflunisal; Flufenamic Acid; Humans; Iodine; Iodobenzoates; Molecular Structure; Prealbumin; Protein Binding; Thyroxine

2004
Aminocarbonyloxymethyl ester prodrugs of flufenamic acid and diclofenac: suppressing the rearrangement pathway in aqueous media.
    Archiv der Pharmazie, 2007, Volume: 340, Issue:1

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Buffers; Carboxylic Acids; Chromatography, High Pressure Liquid; Diclofenac; Drug Stability; Esters; Flufenamic Acid; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Male; Molecular Structure; Prodrugs; Rats; Rats, Wistar; Water

2007
Determination of degradation pathways and kinetics of acyl glucuronides by NMR spectroscopy.
    Chemical research in toxicology, 2007, Volume: 20, Issue:6

    Topics: Acylation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bile; Chromatography, Liquid; Cyclooxygenase Inhibitors; Diclofenac; Drug Stability; Flufenamic Acid; Glucuronides; Half-Life; Ibuprofen; Indomethacin; Kinetics; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mefenamic Acid; Molecular Structure; Rats; Rats, Sprague-Dawley; Stereoisomerism; Technology, Pharmaceutical; Tolmetin

2007
Solubility of sparingly soluble drug derivatives of anthranilic acid.
    The journal of physical chemistry. B, 2011, Mar-24, Volume: 115, Issue:11

    Topics: 1-Octanol; Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Diclofenac; Ethanol; Flufenamic Acid; Hydrogen Bonding; Hydrogen-Ion Concentration; Models, Chemical; Molecular Structure; Niflumic Acid; ortho-Aminobenzoates; Solubility; Solvents; Spectrophotometry, Ultraviolet; Thermodynamics; Transition Temperature; Water

2011
Assessing the removal of pharmaceuticals and personal care products in a full-scale activated sludge plant.
    Environmental science and pollution research international, 2012, Volume: 19, Issue:5

    Topics: Adsorption; Diclofenac; Flufenamic Acid; Gas Chromatography-Mass Spectrometry; Hydroxyzine; Ibuprofen; Indapamide; Perfume; Pharmaceutical Preparations; Sewage; Solid Phase Extraction; Ultraviolet Rays; Waste Disposal, Fluid; Water Pollutants, Chemical

2012
Superoxide anion mediates the L-selectin down-regulation induced by non-steroidal anti-inflammatory drugs in human neutrophils.
    Biochemical pharmacology, 2013, Jan-15, Volume: 85, Issue:2

    Topics: ADAM Proteins; ADAM17 Protein; Adolescent; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Communication; Cell Line, Transformed; Cell Membrane; Cell Movement; Cells, Cultured; Child; Diclofenac; Down-Regulation; Flufenamic Acid; Granulomatous Disease, Chronic; Human Umbilical Vein Endothelial Cells; Humans; L-Selectin; Male; Mice; Mice, Mutant Strains; NADPH Oxidases; Neutrophils; Superoxides

2013
Aryl/heteroaryl Substituted Celecoxib Derivatives as COX-2 Inhibitors: Synthesis, Anti-inflammatory Activity and Molecular Docking Studies.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2017, Volume: 13, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Flufenamic Acid; Male; Molecular Docking Simulation; Rats, Wistar

2017
Transdermal Permeation and Skin Retention of Diclofenac and Etofenamate/Flufenamic Acid From Over-the-Counter Pain Relief Products.
    Journal of pharmaceutical sciences, 2021, Volume: 110, Issue:6

    Topics: Administration, Cutaneous; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Flufenamic Acid; Gels; Humans; Pain; Permeability; Skin Absorption

2021
Metabolism of non-steroidal anti-inflammatory drugs (NSAIDs) by Streptomyces griseolus CYP105A1 and its variants.
    Drug metabolism and pharmacokinetics, 2022, Volume: 45

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Bacterial Proteins; Cytochrome P-450 Enzyme System; Diclofenac; Flufenamic Acid; Humans; Ibuprofen; Meclofenamic Acid; Mefenamic Acid; Streptomyces

2022