fludarabine and pentostatin

fludarabine has been researched along with pentostatin in 76 studies

Research

Studies (76)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's40 (52.63)18.2507
2000's29 (38.16)29.6817
2010's6 (7.89)24.3611
2020's1 (1.32)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Benfenati, E; Raska, I; Toropov, AA; Toropova, AP1
Atalay, RC; Demir, Z; Guven, EB; Kazak, C; Ozbey, S; Tuncbilek, M1
Cheson, BD8
Kantarjian, H; Keating, MJ; Koller, C; O'Brien, S; Plunkett, W; Robertson, L1
Phyliky, RL; Tefferi, A1
Gribbin, TE1
Juliusson, G1
Dighiero, G2
Gollard, R; Lee, TC; Piro, LD; Saven, A1
Byrd, JC; Diehl, LF; Freiman, J; Hertler, AA; Kweder, SL; Weiss, RB1
Hiddemann, W; Pott-Hoeck, C1
Hakimian, D; Tallman, MS1
Estey, EH; Jaiyesimi, IA; Kantarjian, HM1
Benner, A; Bentz, M; Cabot, G; Coy, J; Diehl, D; Döhner, H; Fischer, K; Galle, PR; Hansen, K; Hunstein, W; Lichter, P; Poustka, A; Schlenk, R; Stilgenbauer, S; Volkmann, M1
Piro, LD; Saven, A2
Saven, A1
Cheson, BD; Foss, FM; Sorensen, JM; Vena, DA1
Bendandi, M; Buzzi, M; Farabegoli, P; Martinelli, G; Ottaviani, E; Salvucci, M; Tosi, P; Visani, G; Zaccaria, A; Zinzani, PL1
Beran, M; Estey, E; Kantarjian, H; Keating, MJ; Koller, C; O'Brien, S; Robertson, LB1
Bapat, A; Goldberg, J; Goldman, N; Gordon, R; Gryn, J1
Johnson, SA2
Adam, Z; Hejlová, N; Vorlícek, J1
Gandhi, V; Plunkett, W1
Beran, M; Cortes, J; Kantarjian, H; Keating, M; Koller, C; O'Brien, S; Talpaz, M1
Bergmann, L1
Petryshyn, RA; Slomiany, DJ; Woldehawariat, G1
Catovsky, D; Dyer, MJ; Emmett, E; Hale, G; Kelsey, SM; Mackay, HJ; Newland, AC; Thornton, P; Waldmann, H1
Bolam, S; Orchard, JA; Oscier, DG1
Christopherson, RI; Mulligan, SP; Szabados, E; Wilson, PK1
Flandrin, G; Maloisel, F; Troussard, X1
Machaczka, M; Rucińska, M; Skotnicki, AB; Załuska, A1
Barrett, J; Cheson, BD; Freidlin, B; Vena, DA1
Honma, Y; Niitsu, N; Umeda, M1
Bosanquet, AG; Bosanquet, MI1
Catovsky, D; Dearden, CE; Matutes, E1
Beer, M; Byrd, JC; Grever, MR; Lucas, MA; Waselenko, JK1
Foss, FM1
Johnson, SA; Thomas, W1
Weiss, MA1
Owen, RG1
Bashey, A1
Itälä, M; Remes, K1
Glasmacher, A; Gorschlüter, M; Mey, U; Pralle, H; Schmidt-Wolf, I; Strehl, J; Ziske, C1
Aliff, TB; Frankel, SR; Horgan, D; Jurcic, JG; Kossman, SE; Lamanna, N; Maslak, PG; Scheinberg, DA; Weiss, MA1
Robak, T1
Pettitt, AR1
Gartenhaus, RB; Nabhan, C; Tallman, MS1
Christopherson, RI; Mulligan, SP; Wilson, PK1
Lamanna, N; Weiss, M1
Culligan, DJ; Johnston, PW; Milner, BJ; Mittal, S1
Kay, NE1
Bohlius, J; Greil, R; Pall, G; Richards, S; Schwarzer, G; Steurer, M2
Aribi, A; Faderl, S; Ferrajoli, A; Huh, Y; Kantarjian, H; Keating, M; O'brien, S; Ravandi, F; Wierda, W1
Robak, P; Robak, T1
Christian, BA; Lin, TS1
Lamanna, N; Sauter, C; Weiss, MA1
Kay, NE; Lamanna, N1
Amarnath, S; Buxhoeveden, N; Felizardo, TC; Foley, J; Fowler, DH; Mariotti, J; Massey, PR; Mossoba, ME; Ryan, K; Taylor, J1
Asmar, L; Boehm, KA; Di Bella, N; Hyman, W; Lyons, RM; Reynolds, C; Richards, DA; Robbins, GJ; Vellek, M; Zhan, F1
Foltynski, P; Ladyzynski, P; Molik, M1
Hogan, JJ; Weiss, BM1
Dimitrova, D; Kanakry, JA1

Reviews

47 review(s) available for fludarabine and pentostatin

ArticleYear
New antimetabolites in the treatment of human malignancies.
    Seminars in oncology, 1992, Volume: 19, Issue:6

    Topics: Animals; Antimetabolites, Antineoplastic; Cladribine; Clinical Trials as Topic; Drugs, Investigational; Forecasting; Humans; Immunosuppression Therapy; Leukemia; Lymphoma; Pentostatin; Purines; Vidarabine

1992
A clinical update on chronic lymphocytic leukemia. II. Critical analysis of current chemotherapeutic modalities.
    Mayo Clinic proceedings, 1992, Volume: 67, Issue:5

    Topics: 2-Chloroadenosine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Chlorambucil; Deoxyadenosines; Dose-Response Relationship, Drug; Histocompatibility Testing; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Prednisone; Prognosis; Survival Rate; Vidarabine

1992
New purine analogues for the treatment of chronic B-cell malignancies.
    Henry Ford Hospital medical journal, 1991, Volume: 39, Issue:2

    Topics: 2-Chloroadenosine; Antineoplastic Agents; Cladribine; Clinical Trials as Topic; Deoxyadenosines; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Vidarabine

1991
Immunological and genetic abnormalities in chronic lymphocytic leukaemia. Impact of the purine analogues.
    Drugs, 1994, Volume: 47 Suppl 6

    Topics: Antineoplastic Agents; Chromosome Aberrations; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 13; Cladribine; Humans; Immunity, Cellular; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Vidarabine

1994
Potential immunological action of purine nucleoside analogues.
    Drugs, 1994, Volume: 47 Suppl 6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cladribine; Humans; Immunosuppressive Agents; Leukemia; Pentostatin; Purine Nucleosides; Vidarabine

1994
The optimal management of hairy cell leukaemia.
    Drugs, 1995, Volume: 49, Issue:6

    Topics: Antineoplastic Agents; Cladribine; Combined Modality Therapy; Granulocyte Colony-Stimulating Factor; Humans; Interferons; Leukemia, Hairy Cell; Pentostatin; Splenectomy; Vidarabine

1995
Infectious and immunosuppressive complications of purine analog therapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:9

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cladribine; Humans; Immune Tolerance; Infections; Pentostatin; Purines; Vidarabine

1995
Purine analogs in the treatment of low-grade lymphomas and chronic lymphocytic leukemias.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1995, Volume: 6, Issue:5

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Cladribine; Humans; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Pentostatin; Purines; Vidarabine

1995
Purine nucleoside analogs: emerging roles in indolent lymphoproliferative disorders.
    Blood, 1995, Oct-01, Volume: 86, Issue:7

    Topics: Antineoplastic Agents; Cladribine; Clinical Trials as Topic; Drug Resistance; Humans; Lymphoproliferative Disorders; Pentostatin; Purine Nucleosides; Vidarabine

1995
Advances in therapy for hairy cell leukemia. A review.
    Cancer, 1993, Jul-01, Volume: 72, Issue:1

    Topics: 2-Chloroadenosine; Deoxyadenosines; Forecasting; Granulocyte Colony-Stimulating Factor; Humans; Interferons; Leukemia, Hairy Cell; Male; Pentostatin; Splenectomy; Vidarabine

1993
The newer purine analogs. Significant therapeutic advance in the management of lymphoid malignancies.
    Cancer, 1993, Dec-01, Volume: 72, Issue:11 Suppl

    Topics: Antineoplastic Agents; Cladribine; Humans; Leukemia; Lymphoma; Pentostatin; Vidarabine

1993
Purine analogs in lymphoproliferative disorders.
    Leukemia & lymphoma, 1993, Volume: 11 Suppl 2

    Topics: Antineoplastic Agents; Cladribine; Humans; Leukemia; Lymphoma, Non-Hodgkin; Lymphoproliferative Disorders; Multiple Myeloma; Pentostatin; Vidarabine

1993
Comparative efficacy of the newer nucleosides (fludarabine, 2'-deoxycoformycin, and 2-chlorodeoxyadenosine) in the treatment of indolent lymphoid malignancies.
    Seminars in hematology, 1993, Volume: 30, Issue:4 Suppl 6

    Topics: Antineoplastic Agents; Cladribine; Clinical Trials as Topic; Humans; Leukemia; Lymphoma; Molecular Structure; Pentostatin; Purine Nucleosides; Vidarabine

1993
Neurotoxicity of purine analogs: a review.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1994, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Female; Humans; Male; Middle Aged; Nervous System; Nervous System Diseases; Pentostatin; Purine Nucleosides; Vidarabine

1994
Nucleoside analogs in treatment of chronic lymphocytic leukemia.
    Leukemia & lymphoma, 1993, Volume: 10 Suppl

    Topics: Antineoplastic Agents; Cladribine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Survival Rate; Vidarabine

1993
Purine analogues in the management of lymphoproliferative diseases.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1996, Volume: 8, Issue:5

    Topics: Antineoplastic Agents; Cladribine; Humans; Lymphoproliferative Disorders; Pentostatin; Vidarabine

1996
[Treatment of chronic lymphatic leukemia].
    Vnitrni lekarstvi, 1996, Volume: 42, Issue:8

    Topics: Antineoplastic Agents; Cladribine; Humans; Interferon-alpha; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Prognosis; Vidarabine

1996
2-Chlorodeoxyadenosine treatment of lymphoma.
    Cancer treatment and research, 1996, Volume: 85

    Topics: Adenosine Deaminase; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cladribine; Humans; Lymphoma; Lymphoma, B-Cell; Lymphoma, T-Cell, Cutaneous; Pentostatin; Vidarabine; Waldenstrom Macroglobulinemia

1996
Pharmacology of purine nucleoside analogues.
    Hematology and cell therapy, 1996, Volume: 38 Suppl 2

    Topics: Animals; Antineoplastic Agents; Cladribine; Hematologic Neoplasms; Humans; Pentostatin; Purine Nucleosides; Vidarabine

1996
Adverse and beneficial immunological effects of purine nucleoside analogues.
    Hematology and cell therapy, 1996, Volume: 38 Suppl 2

    Topics: Animals; Antineoplastic Agents; Cladribine; Humans; Immunosuppressive Agents; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Purine Nucleosides; Vidarabine

1996
Perspectives on purine analogues.
    Hematology and cell therapy, 1996, Volume: 38 Suppl 2

    Topics: Antineoplastic Agents; Cladribine; Forecasting; Humans; Leukemia; Pentostatin; Purines; Vidarabine

1996
Present status of purine analogs in the therapy of chronic lymphocytic leukemias.
    Leukemia, 1997, Volume: 11 Suppl 2

    Topics: Antineoplastic Agents; Cladribine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Prognosis; Recurrence; Remission Induction; Vidarabine

1997
Therapy for previously untreated chronic lymphocytic leukemia: a reevaluation.
    Seminars in hematology, 1998, Volume: 35, Issue:3 Suppl 3

    Topics: Antineoplastic Agents; Cladribine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Randomized Controlled Trials as Topic; Vidarabine

1998
Hairy cell leukemia. What is new forty years after the first description?
    Hematology and cell therapy, 1998, Volume: 40, Issue:4

    Topics: 2-Chloroadenosine; Antigens, CD; Antimetabolites, Antineoplastic; Antineoplastic Agents; B-Lymphocytes; Bone Marrow; Clinical Trials as Topic; Deoxyadenosines; Humans; Immunologic Factors; Interferon Type I; Leukemia, Hairy Cell; Neoplasm Proteins; Neoplasms, Second Primary; Neoplastic Stem Cells; Pentostatin; Receptors, Antigen, T-Cell, gamma-delta; Recombinant Proteins; Splenectomy; Vidarabine

1998
[Hairy cell leukemia--a potentially curable malignancy. Selected aspects of purine analog therapy].
    Przeglad lekarski, 1998, Volume: 55, Issue:7-8

    Topics: Antineoplastic Agents; Cladribine; Humans; Leukemia, Hairy Cell; Neoplasm, Residual; Pentostatin; Remission Induction; Splenectomy; Vidarabine

1998
Pentostatin (Nipent) and chlorambucil with granulocyte-macrophage colony-stimulating factor support for patients with previously untreated, treated, and fludarabine-refractory B-cell chronic lymphocytic leukemia.
    Seminars in oncology, 2000, Volume: 27, Issue:2 Suppl 5

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Clinical Trials, Phase II as Topic; Disease-Free Survival; Drug Resistance, Neoplasm; Drug Synergism; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Leukemia, B-Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Remission Induction; Vidarabine

2000
Combination therapy with purine nucleoside analogs.
    Oncology (Williston Park, N.Y.), 2000, Volume: 14, Issue:6 Suppl 2

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Deoxyadenosines; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Interferons; Lymphoma, B-Cell; Lymphoma, T-Cell; Male; Middle Aged; Pentostatin; Purine Nucleosides; Treatment Outcome; Vidarabine

2000
Therapeutic potential of purine analogue combinations in the treatment of lymphoid malignancies.
    Hematological oncology, 2000, Volume: 18, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cladribine; Clinical Trials as Topic; Drug Synergism; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Pentostatin; Purines; Vidarabine

2000
Novel treatment strategies in chronic lymphocytic leukemia.
    Current oncology reports, 2001, Volume: 3, Issue:3

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cladribine; Cyclophosphamide; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Pentostatin; Randomized Controlled Trials as Topic; Sex Factors; Vidarabine

2001
Nucleoside analogues in the treatment of haematological malignancies.
    Expert opinion on pharmacotherapy, 2001, Volume: 2, Issue:6

    Topics: Antimetabolites, Antineoplastic; Arabinonucleosides; Biological Transport; Cladribine; Clinical Trials as Topic; Cytarabine; Cytosine; Deoxycytidine; Dioxolanes; Economics, Pharmaceutical; Gemcitabine; Guidelines as Topic; Hematologic Neoplasms; Humans; Molecular Structure; Nucleosides; Pentostatin; Vidarabine

2001
Treatment options in Waldenström's macroglobulinaemia: the role of the purine analogues.
    Expert opinion on pharmacotherapy, 2001, Volume: 2, Issue:6

    Topics: Alkylating Agents; Antimetabolites; Chlorambucil; Cladribine; Clinical Trials as Topic; Drug Resistance; Drug Therapy, Combination; Guidelines as Topic; Humans; Middle Aged; Pentostatin; Plasmapheresis; Purine Nucleosides; Quality of Life; Vidarabine; Waldenstrom Macroglobulinemia

2001
Immunosuppression with limited toxicity: the characteristics of nucleoside analogs and anti-lymphocyte antibodies used in non-myeloablative hematopoietic cell transplantation.
    Cancer treatment and research, 2002, Volume: 110

    Topics: Animals; Antibodies, Monoclonal; Antilymphocyte Serum; Cladribine; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Pentostatin; Transplantation, Homologous; Vidarabine

2002
[Nucleoside analogues--new drugs for the treatment of lymphatic cancers].
    Duodecim; laaketieteellinen aikakauskirja, 2001, Volume: 117, Issue:2

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Cladribine; Clinical Trials as Topic; Humans; Leukemia, Lymphoid; Lymphoma; Nucleosides; Pentostatin; Vidarabine

2001
Advances in the treatment of hairy-cell leukaemia.
    The Lancet. Oncology, 2003, Volume: 4, Issue:2

    Topics: Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antigens, CD; Antigens, Differentiation, B-Lymphocyte; Antineoplastic Agents; Cell Adhesion Molecules; Cladribine; Humans; Interferon-alpha; Lectins; Leukemia, Hairy Cell; Neoplasm, Residual; Neoplasms, Second Primary; Pancytopenia; Pentostatin; Receptors, Interleukin-2; Rituximab; Sialic Acid Binding Ig-like Lectin 2; Spleen; Splenectomy; Splenomegaly; Treatment Outcome; Vidarabine

2003
Purine nucleoside analogues in the treatment of myleoid leukemias.
    Leukemia & lymphoma, 2003, Volume: 44, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cladribine; Clinical Trials as Topic; Cytarabine; Drug Synergism; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Humans; Infant; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Male; Middle Aged; Pentostatin; Peripheral Blood Stem Cell Transplantation; Remission Induction; Salvage Therapy; Transplantation Conditioning; Transplantation, Autologous; Transplantation, Homologous; Treatment Outcome; Vidarabine

2003
Mechanism of action of purine analogues in chronic lymphocytic leukaemia.
    British journal of haematology, 2003, Volume: 121, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Caspases; Cell Division; Cladribine; DNA Damage; Drug Resistance, Neoplasm; Drug Synergism; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Phosphorylation; Tumor Suppressor Protein p53; Vidarabine

2003
Purine nucleoside analogues and combination therapies in B-cell chronic lymphocytic leukemia: dawn of a new era.
    Leukemia research, 2004, Volume: 28, Issue:5

    Topics: Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antibodies, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Rituximab; Vidarabine

2004
Purine analogs in leukemia.
    Advances in pharmacology (San Diego, Calif.), 2004, Volume: 51

    Topics: Antineoplastic Agents; Cladribine; Humans; Leukemia; Pentostatin; Purines; Stem Cell Transplantation; Vidarabine

2004
Purine analogue-based chemotherapy regimens for patients with previously untreated B-chronic lymphocytic leukemia.
    Seminars in hematology, 2006, Volume: 43, Issue:2 Suppl 2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Purine Nucleosides; Risk Assessment; Treatment Outcome; Vidarabine

2006
Single-agent purine analogues for the treatment of chronic lymphocytic leukaemia: a systematic review and meta-analysis.
    Cancer treatment reviews, 2006, Volume: 32, Issue:5

    Topics: Anemia, Hemolytic; Antineoplastic Agents; Cladribine; Disease-Free Survival; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Randomized Controlled Trials as Topic; Survival Analysis; Treatment Outcome; Vidarabine

2006
Purine antagonists for chronic lymphocytic leukaemia.
    The Cochrane database of systematic reviews, 2006, Jul-19, Issue:3

    Topics: Antineoplastic Agents; Chlorambucil; Cladribine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Randomized Controlled Trials as Topic; Vidarabine

2006
Current treatment options in prolymphocytic leukemia.
    Medical science monitor : international medical journal of experimental and clinical research, 2007, Volume: 13, Issue:4

    Topics: Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antibodies, Neoplasm; Cladribine; Drug Therapy; Humans; Leukemia, Prolymphocytic; Pentostatin; Purine Nucleosides; Rituximab; Splenectomy; Stem Cell Transplantation; Vidarabine

2007
Antibody therapy for chronic lymphocytic leukemia.
    Seminars in hematology, 2008, Volume: 45, Issue:2

    Topics: Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antibodies, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophosphamide; Disease Progression; Disease-Free Survival; Drugs, Investigational; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Mutation; Pentostatin; Rituximab; Vidarabine

2008
Pentostatin in chronic lymphocytic leukemia.
    Expert opinion on drug metabolism & toxicology, 2008, Volume: 4, Issue:9

    Topics: Adenosine Deaminase Inhibitors; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Vidarabine

2008
Pentostatin treatment combinations in chronic lymphocytic leukemia.
    Clinical advances in hematology & oncology : H&O, 2009, Volume: 7, Issue:6

    Topics: Age Factors; Aged; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antibodies, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase II as Topic; Cyclophosphamide; Drug Administration Schedule; Forecasting; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Middle Aged; Mitoxantrone; Multicenter Studies as Topic; Pentostatin; Rituximab; Salvage Therapy; Treatment Outcome; Vidarabine

2009
A network meta-analysis of progression free survival and overall survival in first-line treatment of chronic lymphocytic leukemia.
    Cancer treatment reviews, 2015, Volume: 41, Issue:2

    Topics: Age Factors; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Bayes Theorem; Bendamustine Hydrochloride; Chlorambucil; Cyclophosphamide; Disease-Free Survival; Humans; Kaplan-Meier Estimate; Leukemia, Lymphocytic, Chronic, B-Cell; Markov Chains; Nitrogen Mustard Compounds; Pentostatin; Physical Fitness; Proportional Hazards Models; Randomized Controlled Trials as Topic; Rituximab; Vidarabine

2015
Bridging the Divide: An Onco-Nephrologic Approach to the Monoclonal Gammopathies of Renal Significance.
    Clinical journal of the American Society of Nephrology : CJASN, 2016, 09-07, Volume: 11, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Bortezomib; Cyclophosphamide; Dexamethasone; Humans; Immunoglobulins; Immunosuppressive Agents; Kidney Diseases; Lenalidomide; Melphalan; Oligopeptides; Paraproteinemias; Pentostatin; Rituximab; Thalidomide; Vidarabine

2016

Trials

3 trial(s) available for fludarabine and pentostatin

ArticleYear
Treatment of chronic myelogenous leukemia with nucleoside analogs deoxycoformycin and fludarabine.
    Leukemia, 1997, Volume: 11, Issue:6

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Drug Administration Schedule; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukocyte Count; Middle Aged; Pentostatin; Vidarabine

1997
T-cell large granular lymphocytic (T-LGL) leukemia: experience in a single institution over 8 years.
    Leukemia research, 2007, Volume: 31, Issue:7

    Topics: Adult; Aged; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antineoplastic Agents; Cyclosporine; Female; Flow Cytometry; Humans; Immunophenotyping; Leukemia, Lymphoid; Leukemia, T-Cell; Male; Middle Aged; Pentostatin; Retrospective Studies; Vidarabine

2007
A Phase III trial of fludarabine, cyclophosphamide, and rituximab vs. pentostatin, cyclophosphamide, and rituximab in B-cell chronic lymphocytic leukemia.
    Investigational new drugs, 2012, Volume: 30, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Pentostatin; Rituximab; Treatment Outcome; Vidarabine

2012

Other Studies

26 other study(ies) available for fludarabine and pentostatin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:4

    Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water

2010
Synthesis of novel substituted purine derivatives and identification of the cell death mechanism.
    European journal of medicinal chemistry, 2015, Jan-07, Volume: 89

    Topics: Antineoplastic Agents; Cell Death; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HCT116 Cells; Hep G2 Cells; Humans; Models, Molecular; Molecular Structure; Purines; Structure-Activity Relationship; Tumor Cells, Cultured

2015
The purine analogs--a therapeutic beauty contest.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1992, Volume: 10, Issue:3

    Topics: 2-Chloroadenosine; Antineoplastic Agents; Cladribine; Deoxyadenosines; Humans; Leukemia; Lymphoma, Non-Hodgkin; Pentostatin; Vidarabine

1992
The purine analogs--a therapeutic beauty contest.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1992, Volume: 10, Issue:5

    Topics: 2-Chloroadenosine; Antineoplastic Agents; Cladribine; Deoxyadenosines; Humans; Leukemia; Pentostatin; Vidarabine

1992
Pentostatin and 2-chlorodeoxyadenosine for hairy-cell leukemia.
    The Medical letter on drugs and therapeutics, 1992, Sep-18, Volume: 34, Issue:879

    Topics: 2-Chloroadenosine; Antineoplastic Agents; Cladribine; Clinical Trials as Topic; Deoxyadenosines; Humans; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Pentostatin; Vidarabine

1992
New drugs in the treatment of chronic lymphocytic leukemia.
    Leukemia, 1992, Volume: 6 Suppl 4

    Topics: Antineoplastic Agents; Cladribine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Vidarabine

1992
Fatal recurrence of autoimmune hemolytic anemia following pentostatin therapy in a patient with a history of fludarabine-associated hemolytic anemia.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1995, Volume: 6, Issue:3

    Topics: Anemia, Hemolytic; Antineoplastic Agents; Autoimmune Diseases; Fatal Outcome; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Pentostatin; Recurrence; Vidarabine

1995
p53 gene deletion predicts for poor survival and non-response to therapy with purine analogs in chronic B-cell leukemias.
    Blood, 1995, 03-15, Volume: 85, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Base Sequence; Chromosome Aberrations; Chromosomes, Human, Pair 17; Female; Gene Deletion; Genes, p53; Humans; In Situ Hybridization, Fluorescence; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Molecular Sequence Data; Pentostatin; Polymorphism, Single-Stranded Conformational; Survival Rate; Vidarabine

1995
Apoptosis induction with three nucleoside analogs on freshly isolated B-chronic lymphocytic leukemia cells.
    American journal of hematology, 1994, Volume: 47, Issue:4

    Topics: Aged; Apoptosis; Cladribine; DNA Damage; Female; Humans; In Vitro Techniques; Interferon-alpha; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Pentostatin; Tumor Cells, Cultured; Vidarabine

1994
Pentostatin increases the acute toxicity of high dose cyclophosphamide.
    Bone marrow transplantation, 1993, Volume: 12, Issue:3

    Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Carmustine; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Synergism; Etoposide; Fatal Outcome; Female; Humans; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Methylprednisolone; Pentostatin; Prednisone; Rats; Rats, Inbred Lew; Salvage Therapy; Shock, Cardiogenic; Ventricular Fibrillation; Vidarabine; Vincristine

1993
Chemotherapeutic purine analogs alter the level of interferon-beta mRNA induced by poly I-poly C in cultured osteosarcoma cells.
    Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 1997, Volume: 17, Issue:5

    Topics: Antineoplastic Agents; Cladribine; Dose-Response Relationship, Drug; eIF-2 Kinase; Gene Expression; Humans; Interferon-beta; Neoplastic Stem Cells; Pentostatin; Poly I-C; Protein Serine-Threonine Kinases; RNA, Messenger; Vidarabine

1997
In vivo 'purging' of residual disease in CLL with Campath-1H.
    British journal of haematology, 1997, Volume: 97, Issue:3

    Topics: Adult; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Neoplasm, Residual; Pentostatin; Vidarabine

1997
Association of myelodysplastic changes with purine analogues.
    British journal of haematology, 1998, Volume: 100, Issue:4

    Topics: 2-Chloroadenosine; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Deoxyadenosines; Female; Humans; Lymphoproliferative Disorders; Male; Myelodysplastic Syndromes; Pentostatin; Vidarabine

1998
New prospects in the treatment of indolent lymphomas with purine analogues.
    The cancer journal from Scientific American, 1998, Volume: 4 Suppl 2

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Deoxycytidine; Drug Resistance, Neoplasm; Gemcitabine; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Pentostatin; Vidarabine

1998
Comparative effects of cladribine, fludarabine and pentostatin on nucleotide metabolism in T- and B-cell lines.
    The international journal of biochemistry & cell biology, 1998, Volume: 30, Issue:7

    Topics: Adenosine Deaminase Inhibitors; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Division; Cladribine; Deoxyribonucleotides; Enzyme Inhibitors; Humans; Kinetics; Leukemia, T-Cell; Lymphoma, B-Cell; Pentostatin; Ribonucleotides; Tumor Cells, Cultured; Vidarabine

1998
Second malignancies as a consequence of nucleoside analog therapy for chronic lymphoid leukemias.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:8

    Topics: Aged; Antineoplastic Agents; Cladribine; Female; Follow-Up Studies; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Neoplasms, Second Primary; Pentostatin; Vidarabine

1999
Myeloid and monocytoid leukemia cells have different sensitivity to differentiation-inducing activity of deoxyadenosine analogs.
    Leukemia research, 2000, Volume: 24, Issue:1

    Topics: Acute Disease; Adenosine Deaminase Inhibitors; Antimetabolites, Antineoplastic; Calcitriol; Cell Differentiation; Cladribine; Deoxyadenosines; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; HL-60 Cells; Humans; K562 Cells; Leukemia, Myeloid; Monocytes; Neoplasm Proteins; Neoplastic Stem Cells; Pentostatin; Tretinoin; Tumor Cells, Cultured; U937 Cells; Vidarabine

2000
Ex vivo assessment of drug response by differential staining cytotoxicity (DiSC) assay suggests a biological basis for equality of chemotherapy irrespective of age for patients with chronic lymphocytic leukaemia.
    Leukemia, 2000, Volume: 14, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Chlorambucil; Cladribine; Comorbidity; Cyclophosphamide; Doxorubicin; Drug Resistance, Neoplasm; Epirubicin; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Methylprednisolone; Middle Aged; Neoplastic Stem Cells; Palliative Care; Pentostatin; Prednisolone; Prognosis; Staining and Labeling; Tumor Cells, Cultured; Vidarabine; Vincristine

2000
Clinical overview of pentostatin (Nipent) use in lymphoid malignancies.
    Seminars in oncology, 2000, Volume: 27, Issue:2 Suppl 5

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Drug Resistance, Neoplasm; Follow-Up Studies; Humans; Immunosuppressive Agents; Leukemia; Leukemia, B-Cell; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Prolymphocytic; Leukemia, T-Cell; Lymphoma; Lymphoma, B-Cell; Lymphoma, T-Cell; Pentostatin; Sezary Syndrome; Survival Rate; Vidarabine

2000
Pentostatin and cyclophosphamide: an effective new regimen in previously treated patients with chronic lymphocytic leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Apr-01, Volume: 21, Issue:7

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cyclophosphamide; Drug Administration Schedule; Drug Resistance; Female; Humans; Immunosuppressive Agents; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Neutropenia; Pentostatin; Thrombocytopenia; Treatment Outcome; Vidarabine

2003
Metabolic response patterns of nucleotides in B-cell chronic lymphocytic leukaemias to cladribine, fludarabine and deoxycoformycin.
    Leukemia research, 2004, Volume: 28, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Humans; Ionomycin; Kinetics; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Nucleotides; Pentostatin; Prognosis; Tumor Cells, Cultured; Vidarabine

2004
A case of hepatosplenic gamma-delta T-cell lymphoma with a transient response to fludarabine and alemtuzumab.
    European journal of haematology, 2006, Volume: 76, Issue:6

    Topics: Adolescent; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Crohn Disease; Cytarabine; Epirubicin; Epstein-Barr Virus Infections; Etoposide; Fatal Outcome; Gene Rearrangement, delta-Chain T-Cell Antigen Receptor; Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor; Hematopoietic Stem Cell Transplantation; Humans; Ifosfamide; Immunosuppressive Agents; Liver; Lymphoma, T-Cell, Peripheral; Lymphoproliferative Disorders; Male; Methylprednisolone; Pentostatin; Receptors, Antigen, T-Cell, gamma-delta; Remission Induction; Spleen; Transplantation, Homologous; Vidarabine

2006
The pentostatin plus cyclophosphamide nonmyeloablative regimen induces durable host T cell functional deficits and prevents murine marrow allograft rejection.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2011, Volume: 17, Issue:5

    Topics: Animals; Antineoplastic Agents; Bone Marrow Transplantation; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cyclophosphamide; Drug Synergism; Female; Graft Survival; Graft vs Host Disease; Immunosuppressive Agents; Interferon-gamma; Interleukin-2; Lymphocyte Depletion; Mice; Mice, Inbred BALB C; Pentostatin; Transplantation Chimera; Transplantation, Homologous; Vidarabine

2011
Beyond fludarabine: pentostatin plus cyclophosphamide are a well-tolerated alternative in reduced intensity conditioning.
    Bone marrow transplantation, 2022, Volume: 57, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Hematopoietic Stem Cell Transplantation; Humans; Pentostatin; Transplantation Conditioning; Vidarabine

2022