flucytosine and rifampin

flucytosine has been researched along with rifampin in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199015 (39.47)18.7374
1990's8 (21.05)18.2507
2000's6 (15.79)29.6817
2010's8 (21.05)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M1
Ekins, S; Williams, AJ; Xu, JJ1
Chovatia, PT; Parekh, HH; Pathak, RB1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Alexandrova, LA; Avdanina, DA; Boykova, YV; Efimenko, TA; Efremenkova, OV; Glukhova, AA; Jasko, MV; Karpenko, IL; Kochetkov, SN; Kolonitskaya, DP; Kost, NV; Negrya, SD; Nuraeva, GK; Shevchenko, OV; Solodinin, AP; Solyev, PN; Volkov, IA; Zhgun, AA1
Fieker, DH; McHenry, MC1
Arroyo, J; Kobayashi, GS; Medoff, G1
O'Morain, C1
Hanna, BA; Keusch, GT; Perloff, M; Ribner, B1
Piersantelli, N; Robert, L1
Kitahara, M; Kobayashi, GS; Medoff, G; Seth, VK1
Pien, FD1
Gittes, RF; Keiller, D; Warshawsky, AB1
Flynn, PM; Hughes, WT; Marina, NM; Rivera, GK1
Polak, A1
Crist, WM; Flynn, PM; Hughes, WT; Jenkins, JJ; Magill, HL; Pearson, T1
Bacher, J; O'Leary, T; Pizzo, PA; Thaler, M1
Araviĭskiĭ, RA; Potyl'chanskaia, OL1
Smith, JW1
Corrado, ML; Cummings, M; Eng, RH; Kramer, M1
Gerding, DN; Harris, C; Hughes, CE; Moody, JA; Peterson, LR1
Frick, P; Oelz, O; Schaer, G; Schaffner, A1
Dupont, B1
Denning, DW1
Hunt, SJ; Mathews, WC; Reed, SL; Torian, B1
Blétry, O; Cassoux, N; Kemali, Z; Le Hoang, P; Le Thi Huong, D; Piette, JC; Wechsler, B1
Guarro, J; Mayayo, E; Pujol, I1
Cahn, P; Canteros, C; Córdoba, S; Davel, G; Guelfand, L; Hochenfellner, F; Kaufman, S; Rodero, L1

Reviews

6 review(s) available for flucytosine and rifampin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Newer antibacterial and antimycotic drugs. Critical appraisal.
    The Medical clinics of North America, 1978, Volume: 62, Issue:5

    Topics: Amikacin; Anti-Bacterial Agents; Antifungal Agents; Cephalosporins; Clindamycin; Flucytosine; Humans; Imidazoles; Penicillins; Rifampin; Spectinomycin; Sulfamethoxazole; Tetracyclines; Tobramycin; Trimethoprim

1978
[Special therapeutic aspects of cryptococcal meningoencephalitis].
    La Clinica terapeutica, 1976, Dec-31, Volume: 79, Issue:6

    Topics: Amphotericin B; Antifungal Agents; Child; Clotrimazole; Cryptococcosis; Cryptococcus neoformans; Drug Therapy, Combination; Estrogens; Female; Flucytosine; Humans; Immunologic Techniques; Male; Meningoencephalitis; Miconazole; Middle Aged; Phagocytosis; Rifampin; Transfer Factor

1976
Combination therapy in systemic mycosis.
    Journal of chemotherapy (Florence, Italy), 1990, Volume: 2, Issue:4

    Topics: Amphotericin B; Aspergillosis; Candidiasis; Cryptococcosis; Drug Synergism; Drug Therapy, Combination; Flucytosine; Humans; Mycoses; Prospective Studies; Rifampin

1990
[Curative treatment of invasive aspergillosis].
    Pathologie-biologie, 1994, Volume: 42, Issue:7

    Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Drug Therapy, Combination; Flucytosine; Humans; Itraconazole; Lung Diseases, Fungal; Rifampin

1994
Treatment of invasive aspergillosis.
    The Journal of infection, 1994, Volume: 28 Suppl 1

    Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Aspergillosis; Cholesterol Esters; Drug Carriers; Drug Therapy, Combination; Flucytosine; Humans; Immunocompromised Host; Infusions, Intravenous; Itraconazole; Liposomes; Opportunistic Infections; Rifampin

1994

Trials

1 trial(s) available for flucytosine and rifampin

ArticleYear
Combination therapy in systemic mycosis.
    Journal of chemotherapy (Florence, Italy), 1990, Volume: 2, Issue:4

    Topics: Amphotericin B; Aspergillosis; Candidiasis; Cryptococcosis; Drug Synergism; Drug Therapy, Combination; Flucytosine; Humans; Mycoses; Prospective Studies; Rifampin

1990

Other Studies

32 other study(ies) available for flucytosine and rifampin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:11

    Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Synthesis, antitubercular and antimicrobial evaluation of 3-(4-chlorophenyl)-4-substituted pyrazole derivatives.
    Bioorganic & medicinal chemistry letters, 2012, Aug-01, Volume: 22, Issue:15

    Topics: Anti-Infective Agents; Antitubercular Agents; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazoles; Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Discovery of novel N
    European journal of medicinal chemistry, 2021, Apr-05, Volume: 215

    Topics: A549 Cells; Animals; Anti-Bacterial Agents; Antifungal Agents; Bacteria; Cytidine; Drug Discovery; Fungi; Humans; Microbial Sensitivity Tests

2021
Therapy of murine aspergillosis with amphotericin B in combination with rifampin of 5-fluorocytosine.
    Antimicrobial agents and chemotherapy, 1977, Volume: 11, Issue:1

    Topics: Amphotericin B; Animals; Aspergillosis; Aspergillus fumigatus; Cytosine; Drug Therapy, Combination; Female; Flucytosine; Mice; Mice, Inbred AKR; Rifampin

1977
Elemental diets in the treatment of Crohn's disease.
    The Proceedings of the Nutrition Society, 1979, Volume: 38, Issue:3

    Topics: Adolescent; Adult; Body Height; Body Weight; Child; Crohn Disease; Female; Flucytosine; Humans; Male; Middle Aged; Prednisone; Rifampin; Tetracycline

1979
Drugs for the treatment of systemic fungal infections.
    The Medical letter on drugs and therapeutics, 1978, Jul-28, Volume: 20, Issue:15

    Topics: Amphotericin B; Clotrimazole; Drug Therapy, Combination; Flucytosine; Humans; Kidney Diseases; Meningitis; Miconazole; Mycoses; Rifampin; Thrombophlebitis

1978
Combination amphotericin B-rifampin therapy for pulmonary aspergillosis in a leukemic patient.
    Chest, 1976, Volume: 70, Issue:5

    Topics: Amphotericin B; Aspergillosis; Aspergillus fumigatus; Drug Synergism; Flucytosine; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Lung Diseases, Fungal; Male; Middle Aged; Radiography; Rifampin

1976
Activity of amphotericin B, 5-fluorocytosine, and rifampin against six clinical isolates of Aspergillus.
    Antimicrobial agents and chemotherapy, 1976, Volume: 9, Issue:6

    Topics: Amphotericin B; Aspergillus; Aspergillus flavus; Aspergillus fumigatus; Cytosine; Flucytosine; Microbial Sensitivity Tests; Rifampin; RNA; Uridine

1976
Treatment of candiduria.
    The Journal of urology, 1977, Volume: 117, Issue:6

    Topics: Amphotericin B; Candidiasis; Cytosine; Drug Resistance, Microbial; Flucytosine; Humans; Rifampin; Urinary Tract Infections

1977
Bilateral renal aspergillosis.
    The Journal of urology, 1975, Volume: 113, Issue:1

    Topics: Adult; Amphotericin B; Aspergillosis; Drug Synergism; Flucytosine; Humans; Kidney Diseases; Male; Rifampin; Therapeutic Irrigation

1975
Candida tropicalis and Candida albicans fungemia in children with leukemia.
    Cancer, 1991, Aug-01, Volume: 68, Issue:3

    Topics: Adolescent; Adult; Amphotericin B; Candida; Candida albicans; Candidiasis; Child; Child, Preschool; Flucytosine; Humans; Infant; Pediatrics; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Rifampin; Risk Factors; Tomography, X-Ray Computed

1991
Aspergillus osteomyelitis in a child treated for acute lymphoblastic leukemia.
    The Pediatric infectious disease journal, 1990, Volume: 9, Issue:10

    Topics: Amphotericin B; Aspergillosis; Child; Femur; Flucytosine; Humans; Male; Osteomyelitis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Rifampin

1990
Evaluation of single-drug and combination antifungal therapy in an experimental model of candidiasis in rabbits with prolonged neutropenia.
    The Journal of infectious diseases, 1988, Volume: 158, Issue:1

    Topics: Agranulocytosis; Amphotericin B; Animals; Antifungal Agents; Candidiasis; Cytarabine; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Flucytosine; Ketoconazole; Neutropenia; Rabbits; Rifampin

1988
[Combined chemotherapy of experimental generalized candidiasis].
    Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology, 1987, Volume: 32, Issue:10

    Topics: Amphotericin B; Animals; Candidiasis; Drug Evaluation, Preclinical; Drug Therapy, Combination; Flucytosine; Methacycline; Mice; Rifampin

1987
Synergism of amphotericin B with other antimicrobial agents.
    Annals of internal medicine, 1973, Volume: 78, Issue:3

    Topics: Amphotericin B; Antifungal Agents; Cytosine; Drug Synergism; Flucytosine; Humans; Mycoses; Rifampin

1973
Susceptibility of dermatiaceous fungi to amphotericin B, miconazole, ketoconazole, flucytosine and rifampin alone and in combination.
    Sabouraudia, 1982, Volume: 20, Issue:2

    Topics: Amphotericin B; Antifungal Agents; Cladosporium; Drug Synergism; Flucytosine; Imidazoles; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Mitosporic Fungi; Piperazines; Rifampin

1982
In vitro activities of amphotericin B in combination with four antifungal agents and rifampin against Aspergillus spp.
    Antimicrobial agents and chemotherapy, 1984, Volume: 25, Issue:5

    Topics: Amphotericin B; Antifungal Agents; Aspergillus; Flucytosine; Ketoconazole; Microbial Sensitivity Tests; Rifampin; Triazoles

1984
Trichosporon capitatum: thrush-like oral infection, local invasion, fungaemia and metastatic abscess formation in a leukaemic patient.
    The Journal of infection, 1983, Volume: 6, Issue:2

    Topics: Abscess; Adult; Amphotericin B; Blood; Female; Flucytosine; Humans; Leukemia, Myeloid, Acute; Mitosporic Fungi; Mycoses; Rifampin; Splenic Diseases

1983
Cutaneous Acanthamoeba infection in the acquired immunodeficiency syndrome: response to multidrug therapy.
    Cutis, 1995, Volume: 56, Issue:5

    Topics: Acanthamoeba; Adult; AIDS-Related Opportunistic Infections; Amebiasis; Amebicides; Amphotericin B; Animals; Anti-Bacterial Agents; Antimetabolites; Antiparasitic Agents; Drug Therapy, Combination; Flucytosine; Humans; Male; Rifampin

1995
[Endogenous infectious endophthalmitis].
    La Revue de medecine interne, 1998, Volume: 19, Issue:9

    Topics: Aged; Amphotericin B; Antifungal Agents; Candidiasis; Drug Therapy, Combination; Endophthalmitis; Flucytosine; Humans; Male; Middle Aged; Ofloxacin; Oxacillin; Rifampin; Staphylococcal Infections; Vitrectomy

1998
In vitro and in vivo experimental activities of antifungal agents against Fusarium solani.
    Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:5

    Topics: Amphotericin B; Animals; Antibiotics, Antitubercular; Antifungal Agents; Drug Therapy, Combination; Flucytosine; Fusarium; Male; Mice; Mycoses; Rifampin

1999
In vitro susceptibility studies of Cryptococcus neoformans isolated from patients with no clinical response to amphotericin B therapy.
    The Journal of antimicrobial chemotherapy, 2000, Volume: 45, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Amphotericin B; Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; Drug Interactions; Drug Resistance, Microbial; Fluconazole; Flucytosine; Humans; Leprostatic Agents; Rifampin; Time Factors

2000